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Cymene

    • Product Name Cymene
    • Alias isopropyltoluene
    • Einecs 202-796-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    515581

    chemical_name Cymene
    molecular_formula C10H14
    molar_mass 134.22 g/mol
    appearance Colorless to pale yellow liquid
    density 0.857 g/cm³
    boiling_point 177°C
    melting_point -68°C
    solubility_in_water Insoluble
    odor Pleasant, aromatic
    flash_point 54°C
    refractive_index 1.491
    cas_number 527-84-4
    main_isomers p-Cymene (para), m-Cymene (meta), o-Cymene (ortho)
    vapor_pressure 0.28 kPa at 25°C
    uses Fragrances, solvents, and chemical intermediate

    As an accredited Cymene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Cymene is packaged in a 500 mL amber glass bottle with a secure screw cap and detailed hazard labeling for safe handling.
    Shipping Cymene should be shipped in tightly sealed containers to prevent leakage and evaporation. It must be stored in a cool, well-ventilated area, away from heat, sparks, and open flames. Ensure proper labeling and adherence to local, national, and international transport regulations for flammable liquids. Handle with appropriate protective equipment.
    Storage Cymene should be stored in a cool, dry, and well-ventilated area, away from heat sources, open flames, and direct sunlight. Keep the container tightly closed and clearly labeled. Store away from strong oxidizing agents, acids, or bases to prevent reactions. Use containers made of compatible materials and avoid prolonged exposure to air to minimize risk of decomposition and flammability.
    Application of Cymene

    Applications of Cymene in Industrial Manufacturing

    As a direct manufacturer with extensive production experience, we support industrial partners worldwide in leveraging cymene’s unique properties in validated downstream sectors. Our quality systems and technical teams work closely with customers to ensure controlled integration of our material into complex industry processes. The following scenarios detail real-world applications, compliance frameworks, practical production rates, and finished product examples enabled by our cymene.

    1. Synthesis of Synthetic Resins and Alkyds for Industrial Coatings

    Manufacturers in the coatings and resins sector use cymene as a starting material and reactive solvent in the synthesis of phenolic and alkyd resins. These resins form critical binders for marine, automotive, and industrial protective coatings. Process engineers value cymene for its aromatic structure, stabilizing polymer chain propagation during batch or continuous alkylation reactions. Batch records and in-process controls track exact introduction rates relative to the selected oil length and phthalic anhydride ratio, with downstream emphasis on purity and by-product minimization. When validating new formulas or adjusting catalyst systems, specifications for cymene input are adjusted within a prescribed window to optimize final resin molecular weight and flow characteristics.

    Industry compliance standards

    • ISO 12944 for coatings corrosion protection
    • ASTM D5643 and ASTM D1640 for resin production and performance testing
    • REACH (EC 1907/2006) registration and assessment in the EU for raw materials
    • US EPA TSCA risk evaluation for substances used in industrial paints

    Typical usage ratio

    • Resin synthesis: 5–18% of reaction mass, adjusted by alkyd chain length and desired volatility

    Downstream process integration

    • Direct addition to alkylation reactors alongside phthalic anhydride and polyols
    • Devolatilization and filtration during batch endpoint
    • Intermediate storage prior to resin blending for paint formulations

    Final product types

    • High-durability marine coatings
    • Automotive top coats and primers
    • Machinery enamel paints
    • Industrial varnishes

    2. Production of Agrochemical Intermediates and Actives

    Agrochemical processors employ cymene as an intermediate, particularly in the synthesis of herbicide and insecticide molecules such as permethrin, cyfluthrin, and knockdown agents where p-cymene’s aromatic ring participates in selective functionalization. The input quantity of cymene is precisely controlled according to batch size, conversion efficiency, and downstream purification requirements, with full traceability maintained from raw material intake through final QC release. Compliance with national and international chemical substance regulations forms a critical foundation; all material lots are accompanied by certificates of analysis and supporting trace documents. Variations in addition rates can arise from the reactivity with halogenation or nitration agents selected by the end user.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • EU Regulation (EC) No 1107/2009 (placing plant protection products on the market)
    • Chinese “Industrial Product Safety Production License” standards for agrochemical manufacturing
    • ISO 9001:2015 for process controls in chemical raw material supply

    Typical usage ratio

    • Intermediate syntheses: 3–12% w/w, tuned by the target active strength and reaction yield targets

    Downstream process integration

    • Addition in controlled reactors prior to catalytic halogenation or nitration steps
    • Intermediate isolation through distillation and crystallization
    • Formulation directly into wettable powders or emulsifiable concentrates

    Final product types

    • Pyrethroid-based pesticide actives (e.g., permethrin, cyfluthrin)
    • Crop protection herbicides (e.g., certain phenoxy acid derivatives)
    • Agrochemical intermediates for downstream functionalization

    3. Aroma and Fragrance Ingredient Manufacturing

    Aroma chemical manufacturers utilize cymene for controlled isomerization and further transformation into aromatic compounds with citrus, mint, or pine olfactory profiles. Enclosed batch or continuous reactors convert cymene to key intermediates for flavor and fragrance compounds such as thymol and carvacrol. Stringent adherence to food and cosmetic safety frameworks guides raw material qualification—the addition ratio depends on targeted conversion efficiency and selected downstream catalytic protocols. Operators monitor exhaustive sensory and purity testing at each stage, suited to global ingredient compliance requirements. Full traceability is enforced through in-process documentation and cross-referencing against food safety standards.

    Industry compliance standards

    • IFRA Standards and EU Cosmetics Regulation (EC) No 1223/2009
    • Food Chemicals Codex (FCC), USP-NF standards for flavor ingredients
    • ISO 9235 for natural aromatic raw materials (applies to extracted/coupled aromatics)
    • Hazard Analysis and Critical Control Points (HACCP) for food-grade manufacturing

    Typical usage ratio

    • Feedstock input: 15–38% per batch, determined by catalyst efficacy and conversion completeness

    Downstream process integration

    • Continuous flow addition to isomerization or oxidation reactors
    • Distillation and fractionation post-reactor
    • Chemical work-up and rectification before compounding or blending

    Final product types

    • Thymol and carvacrol crystals
    • Food flavor enhancers (spice extracts, minty blends)
    • Personal care fragrances (soaps, detergents, air fresheners)
    • Seasoning and beverage flavor bases

    4. Fine Chemicals and Pharmaceutical Intermediate Synthesis

    Cymene supports pharmaceutical manufacturers by enabling aromatic substitution and functionalization, serving as a substrate in the preparation of bulk drug intermediates, such as those for mucolytics or expectorants derived from p-cymene motifs. Qualification of incoming cymene focuses on impurity profiles relevant to ICH Q3A (R2) and region-specific pharmacopoeias. The exact feed percentage is governed by the synthesis path, the required active pharmaceutical ingredient (API) grade, and yield optimization in the main ring transformation sequence. Production managers implement batch documentation protocols throughout, supported by periodic validation and change controls as dictated by regulatory filings.

    Industry compliance standards

    • Good Manufacturing Practice (GMP), ICH Q7 guidelines
    • United States Pharmacopeia (USP), European Pharmacopoeia (EP)
    • ICH Q3A (R2) for impurity limits in pharmaceutical ingredients
    • China Pharmacopeia for APIs and intermediates (CP 2020)

    Typical usage ratio

    • API intermediate synthesis: 6–22% of charge weight, precisely established during process validation and scale-up

    Downstream process integration

    • Dosing into jacketed reactors prior to aromatic substitution, sulfonation, or oxidation steps
    • Solid-liquid separation following crystallization
    • In-process QC sampling at each reaction stage

    Final product types

    • API intermediates for mucolytic and expectorant drugs
    • Synthetic building blocks for over-the-counter pharmaceuticals
    • Fine chemical intermediates for further derivatization

    5. Manufacture of Industrial Solvents and Diluents

    Producers in the paint, adhesive, and specialty fluids sectors select cymene for its controlled volatility, aromatic solvency power, and compatibility with hydrocarbon formulations. Material handlers regulate the mass fraction introduced into solvent blends by tracking batch viscosity, flash point, and evaporation rate—variables critical to meeting user or regulatory requirements in various jurisdictions. Documentation systems and product stewardship programs verify that all additions fulfill environmental and workplace safety mandates, particularly for airborne emissions and solvent recovery processes. Input levels are fine-tuned to application: thinner or cleaning solvent grades demand higher cymene ratios, while adhesive carriers use lower levels to control open time.

    Industry compliance standards

    • VOC compliance under US EPA 40 CFR Part 59 and EU Decopaint Directive 2004/42/EC
    • OSHA regulations for flammable and aromatic hydrocarbon processing
    • EN 16516:2017 for emissions from construction solvent products
    • GHS/CLP labeling under UN regulations

    Typical usage ratio

    • Paint thinner blends: 8–24% by weight, modulated by target evaporation and solvency rates
    • Adhesive solvent: 3–12% by formulation specification

    Downstream process integration

    • Metered addition to bulk blending vessels
    • QC-monitored formulation adjustment for viscosity and VOC targets
    • Storage in dedicated solvent tanks prior to canning or drum filling

    Final product types

    • Paint thinners and brush cleaners
    • Industrial adhesives and sealant carriers
    • Degreasing solvent products
    • Custom blend diluents for specialty coatings
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    Certification & Compliance
    More Introduction

    Cymene: Our Perspective as a Direct Chemical Manufacturer

    Bringing Experience and Quality to Industry

    Cymene stands out for us not because of marketing buzz or vague claims, but because we know every step of its production, right from the selection of raw aromatic feedstock to the rigorous controls in fractionation, purification, and final packaging. In our industry circle, people recognize that pushing the limits on purity and traceability secures better performance where it counts—the user’s processes.

    We produce cymene in both the p-cymene and m-cymene isomeric forms, though the p-form remains our core offering due to its favorable odor, clean profile, and higher performance in applications where aroma and solvency really matter. We regularly analyze and monitor lot consistency above 99% purity, typically achieved by precise distillation and advanced chromatographic controls. Our in-house GC-MS panel runs each batch, not just for assurance but because impurities here throw downstream processes off track.

    Chemical Identity and Manufacturing Consistency

    Cymene, chemically known as 1-methyl-4-(1-methylethyl)benzene in the para isomer, arises from methylation of either toluene or direct isopropylation of benzene, depending on required volumes and feedstock pricing curves. While some operators cut corners on feedstock or residuals, we source our base aromatics directly from trusted global vendors with whom we maintain multi-year contracts. This procurement discipline increases cost but it means fewer headaches in our reactors and less cleanup in our distillation columns.

    Batch-to-batch consistency becomes crucial for large-volume users in fragrances, resins, and agricultural intermediates. We've learned over the years that resin cookers and fragrance blenders can trace every minor deviation. Cymene might seem like just another aromatic hydrocarbon on paper but its isomeric purity and residual sulfur—or absence thereof—spell reliability or trouble, especially at volumes exceeding five tons per run. Downstream problems at the customer site, such as yellowing or unpredictable gelling, nearly always trace to poor isomer control or missed residuals in manufacturing. Case histories from our technical support confirm this time and again.

    Why Cymene Matters Across Sectors

    Industrially, cymene carries a strong demand in the synthesis of p-cresol, herbicidal precursors, and as an intermediate in the formulation of fragrances and disinfectants. Pharmaceutical manufacturers draw on our product when they require a relatively nontoxic solvent with low volatility, suitable for active ingredient isolation. Our technical team gets detailed questions from extractors regarding solubility limits, phase behavior, and compatibility with stainless and glass-lined vessels. Nothing in these inquiries surprises us, as customers expect answers drawn from direct hands-on handling, not generic formulas from a brochure.

    In the coatings world, some customers look for alternatives to xylenes due to regulatory or odor constraints. Cymene’s naturally mild, citrus-like scent often pushes it into specialty paints, cleaners, or ink formulations where a less aggressive profile is a commercial edge. We don’t simply tout low toxicity or high flash point as bullet points; we give direct feedback based on field trials, such as how cymene handles in automated blending plants with variable agitation and filtration. Our own logistics staff shares input on storage stability, noting that cymene resists peroxide formation and shelf degradation when barrel-handled using standard protocols.

    Technical Specifications: Less Hype, More Reality

    For us, “model numbers” don’t translate to a catalog abstraction but mean a strict internal recipe with assigned identifier codes. We produce grades optimized for different end-uses: the Fragrance/Flavor grade with the lowest sulfur and peroxide impurities, the Industrial grade focused on p-cymene isomer, and Custom grades matching your own process spec. Instead of relying on vague purity ranges, we keep everything benchmarked to the methylethylbenzene content via direct GC, rather than indirect titration or paper specs.

    One thing we don’t gloss over: users should know that trace residuals—chlorides, peroxides, and sulfur organics—impact downstream oxidation and polymerization in resin production. We keep total sulfur below 1 ppm by feeding our process columns only with low-sulfur aromatics, and our custom filtration design removes particulate and organics far beyond regulatory minimums. Our technical support can provide actual analysis reports from archived batches, not just on request but routinely for contract clients.

    Real-World Usage and Process Feedback

    Cymene enters industrial use as a process solvent, aroma carrier, agricultural chemical intermediate, and occasionally as a non-traditional cleaning agent. We often get requests from production managers in resin facilities looking for robust alternatives to denser, more toxic aromatics. For those shifting away from volatile or regulated solvents, cymene finds a home in closed-loop blending systems because it doesn’t foul filters or corrode transfer lines when handled with the right materials (Teflon, stainless 316, and compatible elastomers).

    What we hear from fragrance and flavor users: the true value in our cymene isn’t always obvious from the certificate of analysis. Instead, end users working with citrus or pine oil derivatives report how poor cymene grades throw off top-note balance, while our cymene integrates cleanly with patchouli, tangerine, and cedar, thanks to isomer specificity and absence of interfering aromatics. In resin and polymer production, plant chemists tell us inconsistent flash points and rapid yellowing make other suppliers’ cymene a risk, but our line meets all key flash point specs over repeated batches.

    For agricultural uses, our clients don’t want dramatics about “green chemistry,” but they do want assurances that no off-odors or slow biodegradation will complicate their formulations. Cymene’s biodegradable profile and low aquatic toxicity, confirmed by independent testing, allow integration into various pest control products, albeit with the need for safe storage practices due to flammability.

    Handling, Storage, and Logistics—Lessons Learned the Hard Way

    Not every supplier faces the pains of moving actual drum and bulk loads, but as a manufacturer with direct shipping lines, we’ve dealt with the headaches of condensation, drum expansion, and offloading hazards. Over the years, we’ve shifted most drum product into lined drums with nitrogen blanketing. That move slashed oxidation risk and improved stability over longer warehouses stays, which our clients in tropical regions noticed immediately.

    Large-volume customers moving cargo via ISO tanks or bulk rail often ask about moisture pickup and contamination. Our SOPs rely on closed fill, non-return valves, and regular cargo tank cleaning for every shipment, not just outbound but on the return run. That sets us apart from spot shippers who rent tonnage tanks from anyone with a low quote; our in-house logistics team oversees every tank movement. Customers in the Southeast Asian and Middle Eastern markets have asked about product performance over six-month sea crossings. Our own warehouse samples, tested post-transport, show no significant deterioration in density, color, or odor under these real-world transport durations, assuming correct tank prep up front.

    Comparisons to Other Aromatic Hydrocarbons: Knowledge from Standing at the Reactors

    People often throw cymene into the same bucket as xylenes, ethylbenzene, or trimethylbenzenes. We know the reality diverges once you get into actual plant use. Cymene delivers a higher flash point (typically above 50℃), a hallmark for process safety in high-volume reactors or pilot lines where overpressure and thermal risk can cascade. In contrast, technical xilene grades from some plants bring headaches with higher volatility and inconsistent odor profiles.

    p-Cymene holds a subtle lemon-pine aroma, making it a favorite when product odor affects the marketing shelf (think consumer cleaners, air care, or automotive polishes). Bulk aromatics like toluene or benzene can never fill this slot due to regulatory and sensory constraints. Cymene’s moderate solvency, measured via Hildebrand parameter, matches closely to non-polar carriers, so it blends well with botanical oils, making it viable for both fragrance and extraction tasks. Our technical group regularly advises on cymene-rosin blend ratios in adhesive and tackifier developments—insights we draw from not just lab trials but also feedback from our partners’ production staff after facility scale-ups.

    In the paint and coatings industry, switching from xylene or TMB to cymene gives customers a less aggressive solvent option, though they take note of a slightly slower evaporation rate. We’ve run direct comparison trials to document the impact on drying speed, film gloss, and VOC profiles. A direct benefit comes up in storage: cymene’s greater resistance to oxidation and polymerization, coupled with our filtration, means shelf life extends well beyond one year under standard indoor conditions. Users less familiar with the subtleties may overlook this advantage until they face customer complaints over off-spec paint batches tied to solvent degradation.

    Specialty Applications Built on Direct Input

    Product development teams come to us for cymene support in high-end fragrance molecules, custom polymers, and agricultural intermediates. That’s more than a sales pitch: working hands-on with these development scientists, we see the downstream impacts of minute process changes.

    One R&D partner in the flavors business ran test blends comparing cymene purity across multiple lots. Their results echoed ours: only the batches sourced from feedstock with tight aromatic spec delivered unvarying top notes and a clean blend with no tail-off or off-odors on storage. In resin applications for electronics and adhesives, the team needed cymene with low total halides and peroxides to prevent premature curing and yellowing—criteria we meet with tailored process controls on our lines, not after-the-fact remediation.

    Bio-based chemical innovators sometimes request a sustainability profile for cymene. Our response: the carbon content derives from fossil aromatics, as biomass-based sources lack scalability and price stability right now. Still, cymene’s readily biodegradable under aerobic conditions, which matters for final product regulatory clearance in the EU and US markets.

    Choosing the Right Grade and Unpacking Customer Requirements

    Through long-term contracts and frequent interaction with technical managers, we’ve honed our product grades not as a marketing exercise but as a response to recurring customer issues. We offer three principal formulations:

    We provide full technical documentation, actual batch certificates, and reference samples on request. Our technical staff can visit your site for trials or troubleshooting, ensuring the grade matches process requirements from the ground up. These collaborations rarely end after a single delivery; steady communication and incremental specification tuning keep our partners’ plants running smoothly.

    Opportunities and Hurdles: A Grounded Assessment

    Recent years brought renewed demand in eco-friendly cleaning and agrochemical applications, where customers face stricter regulatory controls on solvent emissions, persistence, and human exposure. From our standpoint, cymene offers a lower-toxicity, biodegradable option compared to chlorinated and some oxygenated solvents. Clients in the EU request full REACH documentation and extended shelf-life test data, which our regulatory affairs team provides based on extensive stability studies. These requests don’t always align with “by-the-book” safety data; they reflect real-world needs for traceability in an era where recalls and audit trails matter.

    A challenge remains in the price and supply volatility for aromatic feedstock. Direct producers like us face rising costs for benzene and toluene, which reverberate through the market. We address this by maintaining multiple site sourcing, hedging purchase contracts, and qualifying at least two upstream feedstock partners. Some smaller traders cut quality to hold prices, but our clients value supply assurance enough to pay for this protection.

    The Role of Manufacturing Expertise in Product Performance

    Hands-on experience gives us an appreciation for how minute changes in feedstock, column operation, or even ambient weather during purification alter cymene output. Operators recognize that day-to-day discipline in temperature control and fractionation produces lots within spec, while shortcuts show up as customer complaints, off-odors, or process failures.

    Over the years, our in-plant quality team has traced every serious customer claim back to actual production deviations. One electronics adhesive client found yellowing in a cured batch after running their line on competitor cymene. Our root cause analysis linked it to trace peroxides and halides, confirmed by cross-checking production notes and shipment history. Our direct response to these issues—closed-loop control, double-stream purification, and ongoing operator retraining—creates consistency at scale.

    Competitors relying on repackaging or bulk imports often face trace contamination, odor variability, or off-spec physicochemical properties. We believe the answer lies not in layers of paperwork, but in direct manufacturing exposure, continuous process investment, and customer-facing transparency.

    Final Thoughts from a Direct Cymene Producer

    Our perspective draws on daily production, process troubleshooting, and direct customer relationships stretching back decades. We have watched cymene evolve from a commodity aromatic into a specialized component for fragrance, resin, and “green” chemistry innovations. Each advancement depended as much on manufacturing rigor as on creative applications by our clients’ R&D teams.

    Offering cymene tested to the tightest impurity and isomer controls, backed by hands-on technical support and credible supply history, means we carry genuine responsibility to those using it in their process lines. Our story as a cymene manufacturer revolves not around abstract formula sheets, but around operational discipline, raw material discernment, and the patience to develop true partnerships with end users.

    In every shipment, we deliver more than just a product code—what reaches your plant results from layered expertise and shared trust built over years of real-world experience. That’s the difference a producer brings to the market, and that’s what keeps us focused on refining product and process, shipment after shipment.