Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

Cyclopentanone

    • Product Name Cyclopentanone
    • Alias CYCLOPEN
    • Einecs 203-631-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    521560

    Chemicalname Cyclopentanone
    Molecularformula C5H8O
    Molarmass 84.12 g/mol
    Casnumber 120-92-3
    Appearance Colorless liquid
    Odor Peppermint-like odor
    Boilingpoint 130.4 °C
    Meltingpoint -51 °C
    Density 0.948 g/cm³ at 20 °C
    Solubilityinwater 15 g/L at 20 °C
    Flashpoint 35 °C (closed cup)
    Vaporpressure 8.8 mmHg at 25 °C

    As an accredited Cyclopentanone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Cyclopentanone is packaged in a 500 mL amber glass bottle with a secure screw cap, labeled with hazard and handling information.
    Shipping Cyclopentanone should be shipped in tightly sealed containers, clearly labeled, and compliant with all local and international transport regulations. It must be protected from physical damage and stored in a cool, well-ventilated area away from sources of ignition, as it is flammable. Appropriate hazard communication and documentation are required during shipping.
    Storage Cyclopentanone should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from heat, sparks, open flames, and direct sunlight. Keep it separate from oxidizing agents and acids. Ensure containers are clearly labeled and protected from physical damage. Use explosion-proof equipment in storage areas, and avoid inhalation or prolonged skin contact with vapors.
    Application of Cyclopentanone

    Applications of Cyclopentanone in Industrial Manufacturing

    Cyclopentanone serves as a high-value intermediate across several chemical sectors, supporting downstream synthesis in specialty, pharmaceutical, and polymer industries. As a manufacturer, we address technical requirements aligned with industry compliance, process formulation, and end-use utility for each real-world application outlined below.

    1. Production of Jasmonate Fragrance Compounds

    Manufacturers employ cyclopentanone as a foundational ketone in the synthesis of methyl jasmonate and related jasmonate derivatives, widely used in perfumery and aroma chemical industries. Due to strict olfactory requirements in fine fragrance formulation, companies rely on its reactivity and purity. Controlled reduction and condensation routes use cyclopentanone for high structural specificity in aroma actives.

    Industry compliance standards

    • IFRA (International Fragrance Association) guidelines for purity and trace materials
    • EU Regulation (EC) No 1223/2009 for cosmetic ingredients, specific to fragrance allergens
    • Good Manufacturing Practice (GMP) for cosmetic ingredients (ISO 22716)
    • REACH registration for substance use in European markets

    Typical usage ratio

    • 10–30% molar ratio as core carbonyl feedstock in cyclopentanone-to-jasmonate synthesis, adjusted based on yield and contamination thresholds

    Downstream process integration

    • Cyclopentanone enters at the condensation and subsequent esterification stages to create the jasmonate skeleton; all critical control points monitor residual solvents and by-products before refinement

    Final product types

    • Methyl jasmonate (aroma chemical)
    • Cyclopentadecanone (macrolide musk)
    • Specialty fragrance ingredients for fine fragrances
    • Flavor ingredients for food essences (with additional regulatory checks)

    2. Agrochemical Intermediate Synthesis

    Agrochemical producers incorporate cyclopentanone in multi-step synthesis to access active pharmaceutical ingredients (APIs) for plant protection compounds, particularly certain herbicides and insecticides. Its cyclic ketone structure allows tailored functionalization, enabling the formation of niche actives with selective mode(s) of action. Purity control and reaction parameters are strictly monitored to minimize impurity carryover in final crop protection agents.

    Industry compliance standards

    • FAO/WHO Specifications and Evaluations for Agricultural Pesticides
    • China GB2763-2023 Maximum Residue Limits for Pesticides in Food
    • ISO 9001 certified quality management for agrochemical precursors
    • GMP for API manufacturing (if further processed to pharmaceutical-use intermediate)

    Typical usage ratio

    • Ranges from 5–40% by weight in the initial condensation or cyclization reactor, based on the specific molecular backbone of the downstream pesticide

    Downstream process integration

    • Cyclopentanone is charged into the early cyclization, acylation, or alkylation step, followed by transformation via chlorination or nitration based on the target molecule; in-line QC ensures minimal residual solvent/matrix interaction.

    Final product types

    • Pyrethroid intermediates
    • Cyclopentanoid herbicides
    • Plant growth regulator APIs
    • Final formulated plant protection products (once further processed and formulated)

    3. Pharmaceutical API Building Block

    Pharmaceutical companies use cyclopentanone as a core five-membered ring building block in complex API synthesis, including antivirals and antihypertensive agents. Through controlled hydrogenation and nucleophilic addition, process chemists create high-value chiral intermediates. Batch-to-batch traceability is maintained under pharmaceutical GMPs, and all input material testing meets pharmacopeial purity benchmarks to safeguard downstream drug substance quality.

    Industry compliance standards

    • ICH Q7 - Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP/NF Monograph compliance for intermediates (where relevant)
    • EDQM TSE (transmissible spongiform encephalopathy) guidelines for European supply
    • 21 CFR Part 211 - US FDA GMP for finished pharmaceuticals (applicable at API stage)

    Typical usage ratio

    • 3–15% by mol in multi-step synthesis, with ratio customized according to route efficiency, impurity profile, and enantiomeric purity requirements

    Downstream process integration

    • Cyclopentanone is added at ring formation or as a precursor to chiral alcohol/amine intermediates; rigorous in-process analytical testing includes GC-MS and NMR finished intermediate analyses.

    Final product types

    • API intermediates for antiviral drugs
    • Chiral synthons for ACE inhibitors
    • Corticosteroid core structures (with further cyclization/hydroxylation)
    • Final pharmaceutical forms after successive downstream processing

    4. Polyamide and Polyester Polymer Production

    Polymer manufacturers use cyclopentanone as a monomer co-feed or reactive diluent, particularly in polyamide and specialty polyester manufacturing. As a strong solvent for certain specialty polymers, it promotes even polymerization and precise control of molecular weight distribution. During melt-phase or solution polymerization, cyclopentanone ensures high dispersion of monomers. Solvent recovery and RTU (ready-to-use) quality checks are maintained to satisfy high-end application demands such as automotive plastics and performance fibers.

    Industry compliance standards

    • ISO 9001 certified QA/QC for engineering plastics
    • RoHS (Restriction of Hazardous Substances Directive) for polymers in electronics
    • FDA 21 CFR 177.1500, if polymer used in food contact applications
    • REACH compliance for use as processing aid in EU markets

    Typical usage ratio

    • 1–10% by weight as co-monomer or chain extender, process-specific adjustment required for viscosity target and polymer backbone type

    Downstream process integration

    • Material is introduced in the initial monomer blend, acting as a polarity-balancing agent and processing solvent; RTO exhaust systems control VOC emissions throughout batch or continuous production

    Final product types

    • Engineering polyamides (for gears, bearings, electronic housings)
    • Specialty polyesters used in high-performance fibers
    • Copolymers for flexible packaging
    • Automotive and appliance plastics

    5. Solvent and Extraction Agent for Specialty Coatings

    Coatings manufacturers and processors use cyclopentanone as a strong polar solvent and carrier in the formulation of resins and high-performance surface coatings. Due to its moderate evaporation rate and solvency power, it supports uniform application in formulations for polyurethane, epoxy, and PVDF-based coatings. During the blending phase, batch control specialists monitor HAP (hazardous air pollutants) thresholds, especially for production of coatings intended for regulatory-volatile markets such as aerospace and electronics.

    Industry compliance standards

    • US EPA 40 CFR Part 63 (NESHAP) for surface coating operations
    • EU VOC Directive (2004/42/EC) for coatings and paints
    • UL GREENGUARD Certification for indoor air emissions (if applied for)
    • ISO 12944 for corrosive protection coatings performance validation

    Typical usage ratio

    • 5–18% by total formulation weight, adjusted for targeted resin compatibility and drying profile

    Downstream process integration

    • Material feeds into pigment dispersion and resin solubilization stages, then maintained in blending tanks prior to filtering and filling; in-line monitoring ensures VOC and odor release parameters remain in specification

    Final product types

    • High-performance polyurethane coatings
    • Epoxy-based protective finishes
    • PVDF specialty architectural coatings
    • Aerospace and electronics-grade lacquers
    Free Quote

    Competitive Cyclopentanone prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Cyclopentanone: Core Insights from the Manufacturing Floor

    Our Commitment to Quality and Consistency

    Cyclopentanone stands out as more than a mid-tier chemical building block. Over decades on the manufacturing floor, we have learned that behind every drum lies precise control, trusted knowhow, and respect for both end users and the chemistry itself. Each lot rolling out from our reactor has undergone deep scrutiny—consistent density, clarity, water content, and purity define every shipment. The difference between lab-grade and actual production quality is rarely visible on a certificate. After years refining reaction conditions and scaling, we reach a Cyclopentanone that offers stable, predictable performance every time a process engineer lifts the lid.

    Purity and Reliable Supply Chains

    No one wants to halt a plant run due to variable solvent residue or off-grade product. Modern industries demand reliable chemical feeds—the tighter the tolerance, the fewer headaches downstream. Our team analyzes for GC purity beyond industry minimums, and we catch trace impurities others might overlook. Even small changes in feedstock or reaction pathway can introduce isomers or water that cause headaches in syntheses or polymerizations. We don’t cut corners with washing, distillation, or packaging, and this diligence means our Cyclopentanone supports precision in sensitive reactions, not disruption.

    Cyclopentanone has a faint camphor odor and a boiling point grouped comfortably in the mid-hundred Celsius range. This profile, tighter than similar ketone solvents, gives better recovery in closed systems. Reactors stay cleaner, and waste disposal decreases. Over time, these characteristics have made our Cyclopentanone a preferred choice when cyclic ketone performance matters.

    Applications—From Pharmaceuticals to Polymers

    Most professionals meet Cyclopentanone through two doors: pharmaceuticals and polymer intermediates. Countless plant tours, and a fair bit of spilled solvent, have taught us how varied those processes can be. In one corridor, it acts as a solvent for active pharmaceutical ingredient synthesis, where unchecked moisture or trace byproducts can compromise a whole batch. In a neighboring hall, it serves as a precursor in the manufacture of adhesives, flavors, and specialty polymers. Consistent composition matters up and down that chain. When manufacturers call us late at night, it’s rarely about price—more often, someone is troubleshooting unexpected reactivity or viscosity issues. Unpacking the problem, we trace it to minor batch variation or contaminant. From these calls, we sharpen our process controls even further.

    What keeps Cyclopentanone reliable isn’t just the hardware or lab spectra. Our people understand its role in cracking cyclopentanol, oxidizing feedstock, and keeping pilot blends on spec. When a facility scales up to thousand-liter reactors, it counts on physical and chemical consistency. Each year brings new technical demands—whether tighter water limits for electronics, or lower aldehyde residues for flavor industries. We adjust our operations, not the burden of compliance, so customers never find themselves revalidating a process just because a shipment changed.

    Sensible Specification: Real Details That Make a Difference

    Specifications for Cyclopentanone mean more than just numbers. Our product typically reaches 99.5% minimum purity by GC, with residual water held under 0.2% by Karl Fischer titration. Density and refractive index hover in the established ranges of 0.948 to 0.950 g/cm³ and 1.436 to 1.438, checked batch by batch. Color standards—haziness or yellow cast—matter most to folks in resin or lacquer synthesis who worry about downstream clarity.

    Packaging may look like an afterthought, but improper sealing leads to ambient moisture uptake. Some global customers request lined steel drums, while domestic buyers prefer high-density polyethylene containers for ease of handling. Shipment timing is often critical. Our inventory system and local storage guarantees orders go out fresh—never product that’s sat idle or weathered.

    Comparisons: Cyclopentanone Beside the Usual Suspects

    In practice, plant chemists consider Cyclopentanone in a family with methyl ethyl ketone, cyclohexanone, and even acetone for certain blends. The key difference turns on reactivity and volatility. Cyclopentanone evaporates slower than acetone, but gives a tighter, more stable reaction profile during condensation or polymerization. Compared to cyclohexanone, Cyclopentanone’s five-membered ring introduces less steric hindrance, giving an edge in some specialty syntheses. In adhesives and coatings, this translates into a more controlled curing process and less odor. Disposing of leftovers is simpler too, since the chemical oxygen demand is lower.

    We’ve investigated substitute routes, but for several downstream customers, switching to other ketones means either a regulatory overhaul or a whole new series of product validations. Few are willing to take on that cost, so consistency in Cyclopentanone quality sits near the top of many raw material lists.

    Some commodity manufacturers lean on methyl ethyl ketone or acetone for price advantages, but this cost saving often evaporates in loss of yield, rising waste, or failed quality checks. Cyclopentanone’s unique structure—a five-membered ring ketone—reacts differently in aldol reactions, ring-opening syntheses, and specific pharmaceutical intermediates. For these applications, nothing else steps into its role.

    Health, Safety, and Regulatory Commitment

    Every factory veteran knows that safety isn’t a paperwork exercise. Cyclopentanone presents moderate flammability and a distinct odor profile—enough to alert operators to leaks but not to overwhelm a workspace. Proper ventilation, closed handling, and spill response are all regular training topics here on the floor. Regulations worldwide keep tightening, especially around VOC emissions and workplace exposure. Our bulk tanks, seals, and vapor recovery systems—designed and executed by engineers who’ve worked decades with this molecule—keep not only our staff but also end-users’ facilities in compliance.

    Each country brings its own paperwork. Europe, the United States, China, and several ASEAN nations now require hazard compliance paperwork and environmental documentation down to the lot level. We provide verified batch certificates, upstream traceability, and can support registration for new markets. This direct link saves our downstream partners weeks of regulatory audit. When the inevitable site inspector questions batch origins or analytical methodology, our technical team is ready with the right documentation.

    Our own packaging team follows strict protocols to avoid cross-contamination. We run periodic third-party audits to make sure every operation aligns with evolving expectations from not just regulators, but the customers themselves. The differences may look small—a new drum liner, updated ventilation, or revised analytical method—but these changes have come about from direct customer conversations. In some cases, they have caught emerging contaminants or flagged batch variation before end-users ever spotted issues in their formulations.

    Solutions for Process Challenges

    Every manufacturer faces production hurdles. One common issue is cyclopentanone’s sensitivity to oxidation. Even trace oxygen ingress during storage can lead to peroxides or subtle product degradation. To counteract this, our storage and loading systems use nitrogen blanketing and rapid drum filling. After seeing real-life instances of peroxide buildup in customer facilities, we adjusted our shelf-life guarantees and inspection program—catching and resolving small issues before they ever reach a customer’s dock.

    Odor control ranks high for many applications, especially flavor and fragrance sectors. Routine headspace GC analysis and sensory checks at critical points in the process catch deviations. If solvents offload above a predetermined odor threshold, we investigate upstream feedstock, reactor operation, and every valve along the transfer line. Over the years, attention to seemingly minor details—gasket material, drum torque, air exposure—has drastically reduced customer complaints.

    Trace water can trouble high-precision syntheses, especially in pharmaceuticals. In one notable case, a client’s yield loss traced back to drum vent design on their line. After site visits and joint troubleshooting, we found the weak link and updated our delivery specs to eliminate similar risk in future batches. Those direct, boots-on-the-ground experiences shape every step of our process.

    Not all solutions are technical. Logistics—something as mundane as drum orientation, weather exposure, or shipment timing—play a significant role in consistent quality. Cyclopentanone can batch degrade if left in sunlit yards or improperly stacked in ocean transit. Our global footprint allows us to plan routes and carrier contracts for both minimum delay and environmental control. Winter shipment? We adjust insulation. Summer? We reinforce cooling. These aren’t afterthoughts, but daily operating realities confronted by those who’ve seen poorly treated shipments ruin months of meticulous production planning.

    Product Integrity from Source to Delivery

    A key advantage for direct manufacturers like us is line-of-sight accountability. Control over precursor selection, continuous process improvement, and employee training delivers measurable differences in final product. We run robust raw material screening before any new supplier enters our system. Each shipment comes directly from where it was made, not repackaged or relabeled by intermediaries. When equipment upgrades improve reproducibility—be it digital temperature controls, better column packing, or faster online monitoring—we roll out changes systematically, then share the technical impact with our customer base. Transparent, traceable improvements foster trust.

    Direct feedback loops matter. A customer’s atypical test result can be investigated three ways: reviewing internal lab logs, checking batch process analytics, or dispatching an expert on-site. Each option draws on years of hands-on problem solving. No handoffs, no trying to retrace steps through a trader. This has become especially critical with increasing supply chain scrutiny, and in sectors like pharmaceuticals or advanced materials, where documentation and repeatable results are audited down to the smallest anomaly.

    In our own facility, we operate continuous-process reactors, not batch operations, for the majority of Cyclopentanone output. Continuous manufacturing brings tighter control over residence time, temperature, and impurity rejection. The result is smoother, more uniform chemical properties. Some partners switching away from batch-based suppliers have reported fewer end-of-line interventions, less scrap, and greater product consistency. The cost of a plant intervention or lost end-batch can dwarf any small price differential on the raw material—it is this perspective that defines our focus.

    Key Considerations Upstream and Down

    Feedstock volatility sometimes gets overlooked by non-manufacturers. Our attention goes beyond the synthetic route itself—we monitor global price and supply trends for precursors like cyclopentene and cyclopentanol. When shortages or volatility hit, we buffer inventory and, if necessary, reroute process schedules. It is an expensive move, but one that prevents customer projects from going dark mid-way through a campaign.

    We keep an eye on environmental factors as well. Any process change—switching from traditional oxidation to catalytic alternatives, for instance—means qualifying both output and downstream compatibility. Regulatory shifts, especially in Europe and North America, keep pushing us to reduce resource use, solvent waste, and potential emissions. Wherever possible, we recover and recycle spent solvents from our own processes, lowering both carbon footprint and waste stream costs. Partners adopting green chemistry protocols can draw on not just marketing claims, but documented process improvements.

    Future Developments and Industry Insight

    Markets and chemistry progress together. Over the past ten years, we have seen increasing demand for high-purity, low-residue Cyclopentanone from electronics and advanced polymer sectors. As design tolerances tighten and final products become more sensitive to trace contaminants, we invest in refining purification, analytical methods, and packaging innovation.

    As research expands possible applications—such as next-generation electrolytes, battery materials, and fine chemical intermediates—the role of reliable, directly sourced Cyclopentanone grows. Rather than speculating on distant innovations, we focus on building a solid, scalable capacity and transparent process chain. Our technical liaisons frequently join customer development teams to offer advice on new application protocols, matching upstream capabilities with the evolving needs of high-tech industries. Through lab-scale sampling, pilot trials, and routine quality communication, we support these new fields by sharing accumulated manufacturing knowledge.

    Close contact with application chemists continues to highlight new requirements, whether anti-yellowing in film applications or ultra-low odor for personal care formulation. Many production improvements come from these ongoing dialogues. The separation from speculative or trader-driven sourcing gives us agility—if a customer brings a new constraint or challenge, we can adapt process steps, adjust analytical focus, or target production scale shifts without third-party bottlenecks. This alignment underwrites years of successful partnerships, proved batch by batch.

    What Sets Direct Manufacturing Apart

    Over time, the real differences between chemical manufacturers and traders come to the surface. From reacting to a subtle change in spec, to answering direct questions about how a material was made, only those who run the reactors know the answers beneath the data sheet. We stand behind every shipment, not from a distance, but with field technicians, plant history, and technical records to back it up. Each inquiry, every technical demand, builds on a foundation of hands-on chemical production and real-world experience.

    With Cyclopentanone, the margin for error is slim. No amount of paperwork substitutes for daily vigilance across the operation. Direct production creates a living connection from process bench to delivery dock, from early supplier discussions to frontline customer feedback. The learning cut over decades filters into every update and batch, making our Cyclopentanone not just a commodity, but a reliable asset in any synthesis or application relying on it.

    As the industry keeps evolving, and quality standards climb, we remain focused on advancing our process, listening to customer needs, and delivering on promises. This approach to manufacturing—as a continuous dialogue, not a static commodity trade—keeps Cyclopentanone a vital component in downstream innovation and everyday production success.