Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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Bromine

    • Product Name Bromine
    • Alias Br
    • Einecs 231-778-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    530654

    name Bromine
    symbol Br
    appearance reddish-brown liquid
    state_at_room_temperature liquid
    oxidation_states -1, +1, +3, +4, +5, +7
    solubility_in_water slightly soluble
    CAS_number 7726-95-6

    As an accredited Bromine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Bromine is packaged in 500 mL amber glass bottles, tightly sealed, with corrosive and toxic hazard labels, and secure leak-proof outer casing.
    Shipping Bromine is shipped in approved, corrosion-resistant containers such as glass bottles, ampoules, or steel drums with inner linings. The containers must be tightly sealed and clearly labeled as hazardous. Transport requires secondary containment, proper ventilation, and temperature control. Strict regulations ensure safety due to its toxic and corrosive nature.
    Storage Bromine should be stored in tightly sealed glass containers, preferably with ground-glass stoppers, in a cool, well-ventilated, and dry area away from direct sunlight and incompatible substances such as organic materials and reducing agents. The storage area must have secondary containment to prevent leaks or spills, and containers should be clearly labeled and handled using appropriate chemical safety protocols.
    Application of Bromine

    Applications of Bromine in Industrial Manufacturing

    Bromine serves as a pivotal raw material across several industrial sectors, facilitating advanced synthesis and process optimization. As a direct manufacturer, we supply high-purity bromine tailored to each industry's regulatory frameworks, formulation requirements, and integration criteria—enabling efficient and compliant production for global producers.

    1. Flame Retardant Synthesis for Plastics and Electronics

    Leading manufacturers utilize bromine to synthesize brominated flame retardants (BFRs), which improve the fire resistance of polymers used in construction, automotive, and electronic applications. Bromine reacts with specific organic molecules to form compounds such as tetrabromobisphenol A (TBBPA) and hexabromocyclododecane (HBCD), each subject to precise quality and purity parameters. The industry closely manages process control systems for safe halogenation, ensuring consistent halogen content as per device and panel specifications. Plant QC labs monitor batch uniformity and HBr emissions per workplace requirements.

    Industry compliance standards

    • IEC 60695-11-10 (Flammability testing)
    • UL 94 (Plastics Flammability Standard)
    • REACH Regulation (EU) 1907/2006 on BFRs
    • RoHS Directive (EU) 2011/65/EU Annex II exemptions for BFRs

    Typical usage ratio

    • 10–17% by weight in TBBPA for printed circuit boards
    • 5–10% in HIPS plastics (varied according to polymer matrix and regulatory limits)
    • Ratio adjustments depend on flammability rating (V-0, V-1) and mechanical properties of end polymer

    Downstream process integration

    • Bromination of bisphenol-A or cyclododecane with elemental bromine at elevated temperatures
    • Inline addition to polyolefin or polyester streams during compounding
    • Real-time monitoring for halogen content prior to pelletization

    Final product types

    • Printed circuit board laminates (FR4, CEM-3)
    • TV and monitor housings
    • Automotive dashboards
    • Enclosures for household electrical devices

    2. Synthesis of Active Pharmaceutical Intermediates (APIs)

    Bromine acts as a critical halogenating agent in the synthesis of active intermediates for pharmaceuticals—including pain relievers, antihistamines, and anti-infectives. It introduces bromine atoms into aromatic rings or aliphatic compounds, allowing targeted functional transformations. Process engineers control stoichiometry and temperature profiles in batch reactors, facilitating high selectivity and minimal by-product formation. GMP standards mandate traceability for bromine batches and residual testing in API output.

    Industry compliance standards

    • ICH Q7A GMP Guidelines for APIs
    • USP–NF Monographs relevant to individual intermediates
    • 21 CFR Part 211 (cGMP for Finished Pharmaceuticals)
    • European Pharmacopoeia monographs

    Typical usage ratio

    • 0.8–1.2 molar equivalents per substrate in bromination stages
    • Optimized based on substrate reactivity and downstream purification complexity
    • Excess bromine scavenged and neutralized post-reaction

    Downstream process integration

    • Charged to jacketed glass-lined reactors or flow systems for controlled bromination
    • Offline and online HPLC monitoring for reaction completion
    • Integration with continuous or batch workup and isolation by crystallization or extraction

    Final product types

    • Brominated pharmaceutical intermediates (e.g., 4-bromobenzoic acid, bromoacetophenone derivatives)
    • Antihistaminic API precursors
    • Cephalosporin side-chains
    • Pain medication building blocks

    3. Water Treatment Chemicals Production

    Water treatment facilities and industrial chemical plants use bromine to formulate hydrobromous acid and bromine-based biocides that control microbial activity in cooling towers, process water loops, and recreational water systems. Bromine's high oxidation potential allows it to act effectively in a broad pH range, especially in high-chloride environments. Material handling protocols emphasize closed-system dosing and corrosion monitoring. Blending accuracy and QA procedures ensure correct bromine residuals in finished biocide concentrates, in line with environmental and safety requirements.

    Industry compliance standards

    • NSF/ANSI 60 (Drinking Water Treatment Chemicals—Health Effects)
    • U.S. EPA FIFRA regulations for biocidal products
    • EN 12671 (European Standard for Aquatic Biocides)
    • OSHA 29 CFR 1910.1200 (Hazard Communication Standard)

    Typical usage ratio

    • Typically 10–20% by weight in sodium bromide biocide concentrates
    • Direct dosing at 1–5 ppm active bromine for cooling tower maintenance
    • Adjusted based on system volume, biofouling level, and local discharge regulations

    Downstream process integration

    • Continuous mixing with NaOH or NaOCl to produce active bromine compounds
    • Integration with digital dosing pumps for real-time addition in water treatment systems
    • Final batch testing for available halogen content and impurity profile

    Final product types

    • Sodium bromide solutions
    • Bromine tablets for pools and spas
    • Bromochlorodimethylhydantoin (BCDMH) blends
    • Industrial water conditioning agents

    4. Oil & Gas Drilling Fluid Additives

    In oil and gas exploration, bromine converts to bromide salts, notably calcium bromide and zinc bromide, for use as dense completion and workover fluids. These bromide brines balance hydrostatic pressure, stabilize wellbores, and suppress formation fluids without solid-phase bridging. Production protocols prioritize low insoluble content and clear brine quality. On-site engineers blend and adjust brine density to match reservoir gradients, accounting for temperature and formation characteristics. Our supply chain meets modular logistics and batch certification requirements for global drilling contractors.

    Industry compliance standards

    • API RP 13J (Testing Brines Used in Oil and Gas Well Drilling and Completion)
    • ISO 13500 (International Standard for Barite and Brines)
    • OSHA 29 CFR 1910.120 (Hazardous Waste Operations and Emergency Response)
    • REACH registered substances requirements (EU)

    Typical usage ratio

    • 30–50% w/w concentration in clear brine fluids (CaBr2 or ZnBr2)
    • Ratio determined by required fluid density (up to 19.2 lb/gal for HPHT wells)
    • Adjustments based on depth, temperature, and well design

    Downstream process integration

    • Direct dissolution and clarification in mobile mixing units
    • Inline specific gravity measurement and filtration before field application
    • Top-up and reclamation stages monitored during well completion

    Final product types

    • Calcium bromide brines
    • Zinc bromide brines
    • Clear brine packer fluids
    • Completion and workover fluid blends

    5. Agricultural Fumigant and Soil Sterilization Agent Manufacturing

    Major agrochemical producers use bromine to manufacture methyl bromide and other fumigants for soil sterilization, quarantine treatment, and post-harvest pest control. Manufacturing involves high-purity reaction with methanol or other alcohols in pressurized reactors. Strict environmental and batch safety guidelines apply, especially considering usage restrictions and required handling protocols to minimize emissions. Quality assurance teams monitor purity, stabilizer content, and absence of contaminants in each lot shipped to downstream formulation plants.

    Industry compliance standards

    • FAO Specifications for Plant Protection Products
    • U.S. EPA Restricted Use Pesticide (RUP) Program under FIFRA
    • International Plant Protection Convention (IPPC) ISPM No. 15 for wood packaging
    • Rotterdam Convention Prior Informed Consent (PIC) Procedure

    Typical usage ratio

    • Stoichiometric conversion (1:1 molar) with methanol for methyl bromide synthesis
    • Final product formulated between 98–99.5% purity by volume
    • Blend ratios for soil use vary by crop, soil type, and national regulations

    Downstream process integration

    • Batch-reacted with alcohols under inert conditions for high conversion
    • Integrated gas condensation and distillation systems for purification
    • Packed in pressure-rated cylinders for supply chain safety compliance

    Final product types

    • Methyl bromide bulk liquid
    • Specialty soil fumigant blends
    • Quarantine pest control agents
    • Wood packaging sterilization chemicals

    6. Synthesis of Specialty Dyes and Pigments

    Bromine supports the fine chemicals industry as an essential brominating reagent in the production of specialty dyes and pigments, especially vat and azo dye intermediates. It enables precise bromo-substitution on complex aromatic structures, which leads to improved color fastness, hue intensity, and compatibility with textile substrates. Synthetic chemists manage reaction parameters and purification to ensure target bromine incorporation without by-products that could affect dispersion or tone. Batch traceability and contaminant residue testing support both export and regulatory qualification for textile applications.

    Industry compliance standards

    • OEKO-TEX Standard 100 annexes (Hazardous Substances Restrictions)
    • REACH Regulation (EU) 1907/2006 concerning dye intermediates
    • EN ISO 105 (Textile Colorfastness Tests)
    • ZDHC Manufacturing Restricted Substances List (MRSL)

    Typical usage ratio

    • 0.7–1.5 molar equivalents per target aromatic substrate
    • Varies with substituent reactivity and desired substitution pattern
    • Precision based on spectrophotometric assay and customer specifications

    Downstream process integration

    • Bromination executed in batch reactors or continuous flow for high-throughput production
    • Multi-stage workup for isomer purification
    • Filtration, drying, and micronization form downstream intermediates ready for formulation

    Final product types

    • Brominated azo dye intermediates
    • Brominated vat dyes
    • Reactive bromine pigments for synthetic fibers
    • Dispersion dyes for polyester and nylon textiles
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    Certification & Compliance
    More Introduction

    Bromine: Our Perspective as a Chemical Manufacturer

    Decades in Bromine Production: Practical Knowledge, Real-World Challenges

    Bromine holds a unique place in the world of elements. Having produced bromine for over thirty years, our team sees this element not as a commodity, but as a driver for innovation across industries. Every batch we manufacture tells a story of careful handling, precise distillation, and rigorous quality control. We have learned why small differences in purity, trace metals, or packaging change the entire downstream application for everyone from water treatment operators to agrochemical synthesis teams.

    Physical and Chemical Properties Matter

    Our standard technical-grade bromine features a purity not less than 99.5% by mass, minimal water content, and iron measured in the single-digit parts-per-million (ppm) range. Reaching these standards consistently challenges even experienced plant operators, especially since bromine exists as a highly volatile reddish-brown liquid at room temperature. We use dry, super-clean reactors and storage tanks lined with corrosion-resistant alloys. Stainless steel fittings and Teflon gaskets are necessities, not luxuries. This protects product quality and safeguards our operators, as bromine’s reactivity can corrode lesser materials overnight.

    We package bromine in welded steel drums and ISO tanks designed for international shipping. Each vessel passes leak integrity tests far stricter than minimum regulatory norms. Experience has shown that any weakness in the packaging not only risks loss but threatens worker safety and can bring an entire production schedule to a halt. We never cut corners on packaging, because we know first-hand how unforgiving bromine can be when allowed to escape containment.

    Beyond the Basics: Purity and Trace Impurities

    Many buyers ask us why two drums of bromine with the same purity by assay sometimes perform differently in their processes. We see this question arise most often from pharmaceutical formulators and specialty flame retardant producers. Bromine’s reactivity means even trace contaminants can catalyze unwanted side reactions or affect color stability in finished goods. Through years of root cause investigations, we found that, for many applications, what sets one supplier’s bromine apart from another’s isn’t only the assay value, but the careful exclusion of organic and metallic residues. Our process minimizes these, not only through upstream controls but with a custom-designed multi-stage distillation train.

    We repeatedly hear from clients who require bromine below 0.05 ppm iron, or who want certified absence of organic halides. Some ask for bromine that exceeds commercial purity standards—more typical in electronics and pharmaceuticals. In these cases, we implement additional quality control protocols, including residual gas analysis and high-sensitivity wet chemistry. Our plant laboratory runs batch-by-batch checks for sulfur, phosphorus, and even mercury, following up with customers if an outlier comes up. This level of precision defines the difference between plain chemical-grade output and bromine tailored for exacting tasks.

    Where Bromine Goes: Water Disinfection, Agrochemicals, Polymers

    Bromine acts as a critical building block for biocides, flame retardants, dyes, and photographic chemicals. In water treatment, bromine-based disinfectants such as sodium bromide or bromochlorodimethylhydantoin need base bromine that’s low in trace organics and halogens. Decades of supply to municipal treatment plants and industrial cooling towers have taught us how subtle product variation ripples through to disinfection results.

    In agrochemicals, ethylene dibromide and methyl bromide once dominated, though regulatory changes have phased out or restricted many older products. Still, brominated herbicides, fumigants, and fungicides depend on bromine free of iron, arsenic, and sulfur. During seasonal production peaks, our quality team pulls samples every four hours and cross-checks batch records, knowing even marginal shifts in feedstock quality can ruin a finished formulation.

    Polymer producers rely on bromine for a variety of brominated flame retardants. Here, color and trace metals dictate commercial acceptance. If a batch picks up color bodies, this downstream turns into off-spec finished polymer batches costing thousands to replace. This link between upstream bromine quality and end-use delivery has made us obsessive about contaminant monitoring—skills we did not acquire from textbooks, but from loss on the plant floor and the demands of technical users.

    Comparisons: Bromine Versus Other Halogens

    Newer entrants to the chemical field often ask why bromine, with its toxic and challenging handling requirements, remains the reagent of choice for so many reactions. Chlorine, for example, is cheaper and widely available. Yet bromine displays a distinct balance between oxidizing power and selectivity. In organic synthesis, it reacts less aggressively than chlorine, which means fewer over-reactions and higher product yields, especially in the delicate alkylation and bromination steps commonly used in pharmaceuticals or specialty polymers.

    Iodine, on the other hand, brings even higher selectivity but at a much steeper price and with less consistent global supply. Our customers find bromine offers the sweet spot between cost, availability, and functional performance. Chlorine’s reactivity often demands extra safety mechanisms in the plant. Bromine lets operators run some processes under milder conditions, reducing corrosion and extending equipment life, as we have seen across dozens of customer pilot plants.

    Modern Bromine Production: Scale, Sustainability, and Supply Security

    Most of the world’s bromine comes from brine deposits—natural underground water with very high bromide content. Extraction involves oxidation and stripping steps that pull elemental bromine from the solution, then detailed purification. We have shifted toward closed-loop water and chemical recovery systems, limiting environmental impact and minimizing hazardous waste. Plant upgrades mean nearly 95% of process effluent is now reprocessed or neutralized on site.

    Recycling side streams, such as bromine-derived spent catalysts or process off-gas, has become standard practice—not just for environmental compliance but also for long-term supply stability. As bromine supply tightens in certain geographies and new applications, such as brominated battery electrolytes, gain traction, these sustainability practices help keep our production costs stable even in periods of feedstock price swings. Regular review of production methods with outside auditors assures us that both safety and environmental records reflect the seriousness with which we approach responsible manufacturing.

    Worker Safety: Lessons Learned and Practices Refined

    Years spent handling bromine have shown us the importance of rigorous safety routines. From full-face respirators to remote-control filling operations, each safety measure draws from direct experience, not just regulatory codes. Personnel go through quarterly safety drills coordinated with local fire departments. All plant team members learn leak containment, emergency neutralization, and first-responder techniques. We have upgraded our alarm systems after past incidents, moving from manual gas detectors to continuous real-time monitors with automatic valve shut-off features.

    Occasionally, customers ask about the difference between bulk bromine and bromine supplied in ampoules or small containers. The handling risks remain the same—the hazards scale with the volume and pressure. Accidental exposure, even from a single cracked ampoule, can cause respiratory issues, burns, or environmental release. We use extensive ventilation and have engineered spill containment trenches into all storage areas. All these features arise from hard-learned lessons, not just good intentions, and are validated after every production run with post-shipment integrity checks.

    Global Supply Chain and Customer Engagement

    Our clients range from multinationals to regional formulators, but for every customer, traceability stands at the center of our value proposition. We keep batch-level records, sample archives, and shipment data for at least a decade. This approach emerged after an international recall years ago, when a customer traced a quality concern to a single drum. An unbroken chain of custody settled the issue and saved all parties costly litigation and lost trust.

    We communicate supply challenges transparently—discussing plant turnarounds, force majeure events, or maritime shipping congestion. COVID-19 and its aftermath reinforced the necessity for open dialogue about commercial commitments. We manage long-term supply contracts and spot orders differently, setting firm production calendars to match the needs of key customers in flame retardants or water treatment. Proactive supply management limits disruption when brine feedstock runs thin or logistics delays pile up.

    Regulatory Pressures and Industry Trends

    Bromine’s profile has changed over the years. Regulations governing both manufacture and end uses have tightened steadily, driving us to reduce discharge, re-engineer processes, and constantly update hazard communication. Our compliance team expected the phasing out of certain brominated flame retardants after the Stockholm Convention. We shifted production into new grades and applications, such as polymeric flame retardants and novel biocides, where bromine remains irreplaceable.

    Environmental and workplace safety audits now span not only local authorities but transnational frameworks. We must certify REACH and GHS compliance, and now navigate emerging PFAS-related regulations, as certain downstream bromine applications overlap with restricted materials. This regulatory focus pushes us toward cleaner, more transparent operations. Technical support staff routinely advise customers on new labeling and downstream compliance issues, recognizing how even small regulatory changes propagate through the supply chain.

    Research, Innovation, and the Future of Bromine Applications

    We see new uses for bromine emerging every year. Recent work in energy storage, for example, spotlights the role of brominated electrolytes in flow batteries for grid-scale power. Our technical team collaborates with R&D labs and product developers, fine-tuning grades for ultra-pure, water-white bromine essential in these applications. Pharmaceutical teams request bromine for innovative intermediates and building blocks in next-generation drugs, where purity and batch consistency drive regulatory acceptance and patent success.

    Over time, even traditional applications such as photographic film chemistry or organic synthesis present new demands, with customers seeking micro-contaminant analysis or documentation of every quality control step. We respond with open records, detailed certificates, and continuous process upgrades. No week passes without a review of technical bulletins, customer feedback, and sample testing. That cycle of feedback spurs improvements in manufacturing, documentation, and shipping logistics.

    Customer Experience: What Sets Our Bromine Apart

    Customer after customer tells us that the difference between suppliers isn’t only cost, but how a team responds when problems arise. Our technical staff stay available for field-support calls and troubleshooting, whether it’s a plant trial gone wrong or a transit delay requiring alternate packaging. We have modified production schedules, expedited air shipments, and arranged joint tank samplings—practices developed not in isolation, but through years of partnership with downstream operators who depend on timely, on-spec product.

    Handling complaints with genuine engagement—delving into lab records, reviewing sample chain, and offering quick replacement loads—makes a difference. We hear from clients who remember how we identified contamination issues, provided solutions, and prevented millions in revenue loss. Successful technical partnerships depend heavily on trust, transparency, and accountability, values steadily forged through every shipment cycle.

    Continuous Improvement—Driven By Operator Experience

    Every improvement in our bromine comes from direct operator feedback combined with plant engineer insight. If drum gaskets fail under specific storage conditions, we upgrade them. If residue builds up during rail shipping in winter, we enhance insulation and add tracing. This flexible response isn’t theoretical; it emerges from daily walkarounds, night shift logs, and safety committee meetings.

    We process continuous input by meeting each month to look for trends in customer returns, out-of-spec notifications, and field failures. A new drum design or specification can arise from a single lost shipment or a customer’s observation about handling ease during plant offloading. These changes show up in specifications, yes, but they arise from the ground-level reality of handling, not bureaucratic product management sheets.

    Differences From Other Products: Real Manufacturing Insights

    Some chemical manufacturers treat bromine as interchangeable with commodity-grade outputs. We see the differences firsthand. Our standard bromine undergoes extended distillation, not because it’s “required by regulation,” but because we’ve measured how each impurity complicates downstream blending, especially for liquid-phase or pharmaceutical syntheses. The upstream control over feedstock purity, adherence to rigorous impurity exclusion, and packaging integrity differentiate our product from lower-cost competitors, and that separation is traceable in how rarely customers find shipment discrepancies or handling incidents. In flame retardant or biocide production, these small distinctions determine whether a formulation takes days or weeks to stabilize. Our team knows that no shortcut in bromine manufacturing comes without a downstream cost—usually paid by the next plant along the chain, sometimes by the ecosystem, occasionally in regulatory fines. We take pride in halting those shortcuts before they reach our customers.

    Closing Thoughts: The Manufacturer’s Outlook

    Our experience in manufacturing and supplying bromine has shaped our approach not only to the product itself but to how we serve our customers and the broader chemical industry. We view every kilogram produced as a testament to both technical skill and hard-earned lessons, built from decades of real-world experience. The uses for bromine continue to expand, but the core of its value remains rooted in transparency, quality, safety, and responsive manufacturing practices. Everything we do comes back to these principles, helping ensure that each drum we ship plays its part in creating safer, more effective, and more sustainable chemical solutions worldwide.