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Benzyl Mercaptan

    • Product Name Benzyl Mercaptan
    • Alias Thiophenol
    • Einecs 202-843-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    604727

    Chemical Name Benzyl Mercaptan
    Molecular Formula C7H8S
    Molecular Weight 124.20 g/mol
    CAS Number 100-53-8
    Appearance Colorless to pale yellow liquid
    Odor Strong and unpleasant, skunk-like
    Boiling Point 194°C (381°F)
    Melting Point -29°C (-20°F)
    Density 1.049 g/cm³ at 20°C
    Solubility in Water Slightly soluble
    Refractive Index 1.589 at 20°C
    Flash Point 77°C (171°F)
    Vapor Pressure 0.2 mmHg at 25°C
    PubChem CID 7506
    UN Number 1992

    As an accredited Benzyl Mercaptan factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Benzyl Mercaptan, 100 mL, is packaged in an amber glass bottle with a secure screw cap and clear hazard labeling.
    Shipping Benzyl Mercaptan should be shipped in tightly sealed containers, protected from light and moisture. It is classified as a hazardous material and must be clearly labeled. Ship in accordance with local, national, and international regulations for toxic and flammable substances, typically under UN1993, class 3, packing group III, using appropriate protective measures.
    Storage Benzyl mercaptan should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from heat, sparks, and open flames. It must be kept away from oxidizing agents and strong acids. Use corrosion-resistant containers, and protect from light. Proper labeling is essential, and the storage area should have appropriate spill containment measures in place.
    Application of Benzyl Mercaptan

    Applications of Benzyl Mercaptan in Industrial Manufacturing

    Benzyl Mercaptan plays a targeted role as a key sulfur-containing intermediate in multiple specialty chemicals and fine chemical manufacturing routes. Below, we detail real-world downstream scenarios where this compound is essential, describing its industrial use, regulatory benchmarks, precise formulation considerations, integration into finished goods production, and resulting end products.

    1. Pharmaceutical Intermediates Synthesis

    In active pharmaceutical ingredient (API) production, benzyl mercaptan serves as a nucleophilic-thiol reagent or protected sulfur source during the multi-step synthesis of cephalosporin antibiotics and select organosulfur pharmaceuticals. Our material supports sulfenylation and thioetherification stages under controlled conditions, maintaining batch consistency in cGMP-compliant facilities. Its inclusion hinges on required yield and impurity profiles aligned with regulatory standards for human therapeutics.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • US FDA 21 CFR Part 211
    • European Pharmacopoeia (Ph. Eur.) and United States Pharmacopeia (USP) monographs
    • REACH (EC 1907/2006) for handling and safety

    Typical usage ratio

    • 0.5–2.5 molar equivalents per targeted reaction, specifically adjusted to substrate reactivity and desired substitution level in penicillin and cephalosporin synthesis steps

    Downstream process integration

    • Charged neat or pre-dissolved in compatible organic solvents to the reaction vessel at nucleophilic substitution or thiol-activation stages, followed by purification and isolation of pharmaceutical intermediates

    Final product types

    • Cephalosporin and penicillin antibiotic derivatives
    • Thioether-containing APIs
    • Intermediate building blocks for advanced pharmaceutical molecules

    2. Agrochemical Synthesis

    Benzyl mercaptan functions as a sulfurizing agent in agrochemical active ingredient synthesis, particularly in constructing sulfur-bridged structures found in certain insecticides and fungicides. Its performance directly influences reaction selectivity and crop protection efficacy, with controlled dosing essential to achieving the required chemical characteristics demanded by agricultural regulatory authorities worldwide.

    Industry compliance standards

    • FAO and WHO specifications for pesticides
    • OECD Good Laboratory Practice (GLP)
    • EU Regulation (EC) No 1107/2009 concerning the placing of plant protection products on the market
    • China GB/T and Industry Standards for agrochemical formulation

    Typical usage ratio

    • 0.8–2.0 molar equivalents in active ingredient synthesis steps, with precise adjustment based on targeted sulfur incorporation in molecular skeletons

    Downstream process integration

    • Added at defined reaction stages to introduce thiol or sulfide functional groups via nucleophilic substitution or as a reducing agent for precursor compounds; followed by product work-up and formulation

    Final product types

    • Sulfur-containing insecticide intermediates
    • Thioether fungicide molecules
    • Plant protection active substances for field formulations

    3. Polymer and Resin Modification

    Benzyl mercaptan acts as a controlled-chain transfer agent and functional end-group modifier in the custom synthesis of specialty polymers such as polyacrylates and epoxy resins. By providing a reactive thiol group, it helps tailor polymer molecular weight distribution and introduces desired functionalization for advanced coatings, adhesives, and composite matrix resins.

    Industry compliance standards

    • ISO 14001 and 9001 Quality Management Systems for chemical manufacturing
    • EU REACH compliance for monomer/reactant safety
    • EPA TSCA Inventory Listing for industrial polymer applications (US)
    • RoHS Directive (2011/65/EU) for electronics-related resin uses

    Typical usage ratio

    • Typically 0.02–0.15% by weight of total monomer charge; adjusted lower for narrow molecular weight control, higher for terminal functionalization requirements

    Downstream process integration

    • Introduced during batch or continuous polymerization steps, dissolved in monomer or solvent phase, driving end-group incorporation and inhibiting uncontrolled chain propagation

    Final product types

    • Thiol-terminated polyacrylates for coatings
    • Epoxy resins with controlled end functionalities for electrical laminates
    • Specialty adhesives with improved substrate adhesion profiles

    4. Odorant Formulation for Natural Gas and LPG

    Its highly characteristic, detectable mercaptan odor profile makes this compound a technical choice for use in specific tailored odorant mixtures for natural gas and liquefied petroleum gas distribution. Its dosing carefully balances detectability for safety with compliance to government-mandated odorization thresholds, preventing gas leaks without altering downstream combustion or corrosion characteristics.

    Industry compliance standards

    • EN 13725 for olfactometry and odor determination
    • US DOT 49 CFR Part 192.625 for natural gas odorization
    • ANSI B149.1-5 for Canada gas safety odorization standards
    • API 2510 for LPG systems

    Typical usage ratio

    • 1–5 ppm (parts per million) by gas volume; tuned based on gas composition and pipeline material factors

    Downstream process integration

    • Metered injection into main gas lines or bottling stations using precision dosing equipment; consistently monitored to align with olfactory detection requirements and regional mandates

    Final product types

    • Treated natural gas distributed for residential and industrial use
    • Odorized LPG cylinders and bulk supply streams
    • Gas leak detection system calibration standards

    5. Aroma and Flavor Ingredient Synthesis (Trace Use Only)

    In the fine chemicals and flavor industry, this sulfur compound serves in micro-quantities as a precursor or modifying agent during the synthesis of character impact aroma molecules, notably for recreating meat, onions, or roasted profiles. Industry practice mandates tight impurity and dosing control to avoid overpowering sensory characteristics, and only permitted levels as a processing aid or intermediate—never as a direct additive in consumer food products.

    Industry compliance standards

    • IFRA Standards (International Fragrance Association)
    • US FDA 21 CFR 172.515 (Food Flavorings - limitations as processing aid only)
    • EU Commission Regulation (EC) No 1334/2008 on flavorings and food ingredients with flavoring properties
    • ISO 9001:2015 for flavor and fragrance production control systems

    Typical usage ratio

    • Typically <0.001% in batch; used strictly as a chemical intermediate, not as an end-use additive, with residual levels minimized through downstream purification (GCMS verification)

    Downstream process integration

    • Applied in the first step of multi-stage aroma molecule synthesis routes via alkylation or oxidation reactions, followed by rigorous downstream removal and quality testing to meet food safety limits

    Final product types

    • Sulfur-imparted aroma intermediates (e.g., methional, sulfurous esters)
    • Key impact flavor and fragrance molecules for industrial further processing
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    Certification & Compliance
    More Introduction

    Benzyl Mercaptan: A Chemist’s Perspective on a Vital Reagent

    In the world of specialty chemicals, Benzyl Mercaptan stands out with its distinctive profile. Our team has produced this compound for years, walking through every phase—from raw material sourcing, synthesis, and purification to packaging. You come across its strong aroma in the plant and instantly recognize its presence. The chemical formula, C7H8S, says little about its practical value on the manufacturing floor, but in the laboratory, chemists see something different. A benzene ring with a thiol group attached brings unique reactivity and handles a surprising number of industrial demands.

    What Sets Benzyl Mercaptan Apart In Our Lineup

    We know from daily practice that not all thiols behave the same. Benzyl Mercaptan’s combination of aromatic and sulfur chemistry gives it properties that window open broad applications, especially where nucleophilic substitution or reduction plays a vital role. Lab specialists look for this molecule when they need a selective sulfur source—its reactivity often helps tackle synthesis challenges other organosulfur compounds can’t.

    Density and boiling point stand out as practical specs—Benzyl Mercaptan averages a density near 1.06 g/cm3 and its boiling point hovers around 195°C, which means it can handle a range of processing conditions without unwanted losses. We always take care with storage and transport; its volatility and aroma ensure attention to safety and handling. Don’t forget the stench: one spilled bottle can turn a warehouse into a skunk pit, a reminder that chemists must weigh practical logistics alongside chemistry.

    Real-World Uses and Daily Relevance

    Benzyl Mercaptan plays a crucial role as a building block in organic synthesis. In pharmaceuticals, we hear from partners who rely on its thiol group to introduce sulfur in specialty intermediates. Our technical team consults frequently with clients developing custom molecules—Benzyl Mercaptan’s reactivity delivers, especially for those working on complex heterocycles or fine chemicals. It slips into the synthesis path of certain fungicides, corrosion inhibitors, polymer additives, and photographic chemicals.

    Its applications in flavor and fragrance testing sometimes surprise customers—chemists use trace levels to replicate unusual natural aromas. On the plant floor, it’s easy to underestimate these niche uses. Over years of manufacturing, we find that its presence in custom synthesis—particularly where controlled sulfur insertion is critical—makes Benzyl Mercaptan hard to substitute.

    Key Differences From Other Mercaptans and Similar Compounds

    Industry knowledge and hands-on mixing reveal the sharpest differences. Compared to simple alkyl mercaptans, Benzyl Mercaptan’s structure balances improved reactivity with a less offensive—though still potent—aroma profile. It isn’t as volatile as methyl or ethyl mercaptan, so losses to evaporation during open processes are less severe. The benzyl group lends more weight and less physical hazard, though chemical reactivity runs high. Unlike some thiophenols, it stays liquid under standard conditions and blends into organic solvents easily.

    As long-time producers, we can trace where Benzyl Mercaptan shines and where it should step back. If you need a sulfur source with high nucleophilicity and manageability in bulk, Benzyl Mercaptan leads over lighter mercaptans. It resists rapid oxidation better than open-chain analogs, letting it survive rigorous synthesis steps that might waste other thiols. Yet, it’s unsuitable where low odor or high volatility are essential, pointing buyers toward lower-molecular-weight options or those with masked thiol groups.

    From our production experience, quality means more than a single purity number. We emphasize chloroform and benzaldehyde content, as trace contaminants challenge downstream processes. For customers synthesizing pharmaceuticals, even minor impurities can cause headaches, so our protocols hammer away at consistency—years of batch data show how critical fine-tuned purification becomes.

    Handling Challenges Unique to Benzyl Mercaptan

    Benzyl Mercaptan’s handling hazards shouldn’t get downplayed. The notorious stench seeps through seals if not managed right. Experienced processors use thick PTFE gaskets, limit transfer steps, and strictly enforce ventilation. We invested early in odor control, with closed systems and specialty carbon filters, after just a few lessons learned from “aromatic incidents.” Chemists new to thiols sometimes underestimate these hazards—warehouse managers never forget.

    Its liquid state eases pumping and metering compared to crystalline thiols, and it dissolves smoothly in common organic solvents, including dichloromethane, toluene, and THF. Field engineers report time saved during bulk loading, as Benzyl Mercaptan minimizes clogging and doesn’t need pre-melting steps that slow production lines using solid alternatives. Beyond logistics, the strong sulfur presence demands chemical-compatible piping and gaskets; a lesson learned from early corrosion surprises.

    Raw Material Sourcing, Quality, and Traceability

    Quality raw benzyl chloride and sodium hydrosulfide drive our Benzyl Mercaptan synthesis. We recognized long ago that off-spec feedstocks lead to downstream purification headaches—removing off-odors, tar, or colored byproducts can kill batch yield. Direct relationships with chlorinated intermediates suppliers let us control quality without middlemen. Our procurement team monitors each shipment with cross-verified instruments before the reactors start up.

    Traceability matters even more for pharmaceutical and food chain clients. We document every lot, logging analytical data, storage conditions, and production notes. Years of audits made us realize that comprehensive records save time during regulatory reviews. For end users, this means no unpleasant surprises in high-spec applications, and a smoother time passing internal or external inspections. To outsiders, this looks like “nice paperwork”—for chemists on tight deadlines, it can mean the difference between project completion and delays.

    Insights Into Manufacturing: From Reactor to Final Packaging

    Every Benzyl Mercaptan batch begins in stainless steel reactors designed for exothermic control. Temperature and pressure influence reaction profiles—uncontrolled, side-products bloom. Early in our plant’s history, we saw the importance of high-volume vent scrubbing. Chlorinated byproducts and mercaptan vapors both call for robust containment to keep both staff and community relations smooth.

    Purification steps process the crude Benzyl Mercaptan through vacuum distillation. Close monitoring of head and tail cut points matters; a few stray fractions in an under-refined product can taint an entire drum. Routine QA/QC samples run through GC-MS and HPLC standards, developed over years of tough customer demands, help fine-tune the approach. Our operators tweak distillation rates depending on the campaign—heavier solvents in winter, lighter rinses in summer—balancing yield and purity batch by batch.

    Final packaging uses steel drums or HDPE containers with lined closures, since sulfur compounds can soften or discolor cheaper plastics. Small lot packaging, aimed at research labs, sits behind proper ventilation and odor barriers, keeping our shipping team on their toes and our customers happy. The lessons from one bad seal—dozens of boxes flagged by couriers for “odors”—led us to triple-check container integrity.

    Addressing Sustainability and Compliance

    Waste and environmental controls make a real difference. The biggest lesson from our early years was that thiol-laden effluents, if handled without care, create regulatory and neighbor problems. We engineered our wastewater streams to neutralize sulfur content before release and invested in closed-loop vapor recovery, so complaints and surprise inspections faded over time. Resource conservation strategies—solvent recovery, heat exchange networks—emerged slowly, nudged along by both cost savings and regulatory incentives.

    Industry regulations and certifications shape every aspect of Benzyl Mercaptan’s journey, from storage through global transit. We spend significant resources every year meeting and exceeding standards like REACH, TSCA, and quality benchmarks expected by pharma and food clients. Staff undergo refresher training on hazardous material handling, not out of formal need, but because our team knows small lapses lead to real safety or compliance issues.

    Supporting Our Partners in R&D and Production

    Many of our relationships begin with a question—can Benzyl Mercaptan help solve a specific synthesis problem? Often, it boils down to a tough nucleophilic substitution where other thiols react too slowly or with poor yield. We offer both technical know-how and logistical support, helping partners find the optimal way to integrate Benzyl Mercaptan into their process, suggesting compatible solvents, temperatures, and reagents based on the results we see at scale.

    Chemical research rarely moves as planned, so our model flexibility helps customers run small-lot trials, then scale up production without disrupting supply. Pharmaceutical developers working to shift a precursor or tweak an API process reach out, sometimes asking for custom purity levels or unusual packaging. Our willingness to collaborate on analytical testing, impurity profiling, and new production batch sizes has yielded deep partnerships and repeat business.

    When someone in the field gets stuck on a scale-up problem, we field calls about everything from solubility to odor shield solutions. We share what we’ve learned—sometimes a checklist for cleaning transfer lines, sometimes a pointer to the right filtration method. Several clients, particularly those moving from kilo lab to pilot plant, say they value real-world guidance more than technical brochures.

    Common Challenges and Our Approach to Solutions

    Off-odors and cross-contamination may not sound like headline issues to outsiders, but they can stall production for hours. A faint trace of Benzyl Mercaptan anywhere in the plant can lead to product recalls in industries like flavoring or advanced materials. We introduced isolation protocols, running designated cleaning cycles and tracking drum life, to keep other product lines uncontaminated. Specialized absorbent mats and local exhausts help, but the key remains respect for the volatility and persistence of organosulfur compounds.

    Unexpected process upsets—blocked transfer lines or clogged filters—trace back, more often than not, to rough joints or slow drains. Early in our experience, we designed line purges and cleaning solutions to keep everything moving. We pass these solutions to our users and routinely update our handling guides as new challenges appear. Continuously improving both product and process means customers avoid costly shut-downs and lost raw materials.

    Building Trust and Earning Confidence

    We view every shipment not as a simple business transaction, but as a trust exercise. Decades of work have taught us why a missed purity mark or delayed delivery triggers real concerns—not just financial, but in downstream production schedules, internal audits, and even end-user safety. By keeping clear communication, supplying in-depth Certificate of Analysis data, and offering flexible logistics, we keep client teams moving forward without undue risk or worry.

    Chemists, plant managers, and R&D staff want partners who understand the real-world pressures of chemical manufacturing. We take every feedback point seriously, logging complaints and following up on batch histories for the rare issues we encounter. Quarterly reviews with our top clients let us re-examine everything from drum sizes to analytical limits and process upsets, cementing the reliability expected of direct manufacturers.

    Looking Ahead: Meeting Evolving Industry Demands

    Changes in environmental standards, supply chain transparency, and technological advances keep the landscape shifting. Our team constantly reviews greener process aids, new odor control media, and analytical techniques for better impurity identification. We experiment with sampling devices, container improvements, and digital traceability so end users never lose sight of the origins or handling story of what they receive.

    Industry expectations no longer stop at material quality—they demand visible engagement with environmental stewardship and safety. Benzyl Mercaptan teaches constant vigilance and a willingness to adapt as both industries and regulations change. Years of hands-on experimentation, troubleshooting, and customer support foster a culture that values expertise and practical knowledge over theory and abstraction.

    Final Thoughts from the Manufacturing Floor

    No matter how advanced synthesis tools become, Benzyl Mercaptan keeps its place as a core specialty reagent. Its specific physical and chemical properties address target reactions that need both high performance and reliability. Day in, day out, our journey with this compound reminds us that making specialty organosulfur chemicals is as much about discipline and attention to detail as it is about pure chemistry. For every batch that leaves our warehouse, the fingerprints of our team—decades of experience and focused care—travel with it to labs and plants around the world.