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Benzoyl Chloride

    • Product Name Benzoyl Chloride
    • Alias Benzoyl chloride
    • Einecs 204-188-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    479436

    Cas Number 98-88-4
    Molecular Formula C7H5ClO
    Molecular Weight 140.57 g/mol
    Appearance Colorless to slightly yellow liquid
    Odor Pungent, irritating odor
    Melting Point -1°C
    Boiling Point 197°C
    Density 1.212 g/cm³ at 20°C
    Solubility In Water Reacts violently
    Flash Point 72°C (closed cup)
    Vapor Pressure 1 mmHg at 29°C
    Autoignition Temperature 500°C

    As an accredited Benzoyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Benzoyl Chloride is packaged in a 500 mL amber glass bottle with a secure, chemical-resistant cap and clear hazard labeling.
    Shipping Benzoyl chloride should be shipped in tightly sealed, corrosion-resistant containers, clearly labeled as a hazardous material. It must be transported under cool, dry conditions, away from moisture, heat, and incompatible substances. Shipping must comply with local and international regulations, such as UN 1736, and only trained personnel should handle its transportation.
    Storage Benzoyl chloride should be stored in a cool, dry, and well-ventilated area, away from moisture, heat, and direct sunlight. It must be kept in tightly sealed containers made of compatible materials such as glass. Avoid storing near acids, bases, alcohols, or oxidizing agents. Clearly label containers and use appropriate safety precautions due to its corrosive and fuming nature.
    Application of Benzoyl Chloride

    Applications of Benzoyl Chloride in Industrial Manufacturing

    As a chemical raw material manufacturer, we supply Benzoyl Chloride to a range of established industrial customers. Our product supports specific downstream processes where tight quality control and precise material integration are critical. Below, we outline the main application routes, highlighting compliance standards, process parameters, and target end products unique to each sector.

    1. Synthesis of Pharmaceutical Intermediates (Benzyl Penicillin and Derivatives)

    Pharmaceutical manufacturers use Benzoyl Chloride primarily for the synthesis of penicillin derivatives and other active pharmaceutical ingredient (API) intermediates. In the benzylation of 6-aminopenicillanic acid (6-APA), Benzoyl Chloride acts as an acylating agent to introduce the benzoyl group, forming key structures like benzylpenicillin (Penicillin G). The process demands stringent impurity control, minimal residual solvents, and batch-to-batch consistency. Our production maintains ultra-low levels of trace metals, and every lot includes full documentation for pharmacopeial compliance and traceability.

    Industry compliance standards

    • USP, EP, JP monographs for APIs and penicillins
    • ICH Q3A/B (Impurities in New Drug Substances/Products)
    • Current Good Manufacturing Practice (cGMP)
    • EU REACH Registration for chemical handling

    Typical usage ratio

    • 1.0–1.1 molar equivalents relative to 6-APA per batch
    • Adjustments based on real-time HPLC monitoring for complete acylation

    Downstream process integration

    • Direct addition to acylation reactors before neutralization step
    • Controlled dosing under alkaline conditions, monitored for by-product minimization
    • Followed by aqueous extraction and purification of API intermediate

    Final product types

    • Benzylpenicillin sodium
    • Benzylpenicillin procaine
    • Benzylpenicillin potassium
    • Other penicillin or cephalosporin derivatives

    2. Manufacture of Benzoyl Peroxide for Polymer and Adhesive Sectors

    Producers of polymerization initiators rely on Benzoyl Chloride to synthesize benzoyl peroxide, a critical catalyst for thermoset resins, acrylics, and unsaturated polyester composites. The chlorination and subsequent reaction with hydrogen peroxide require precise stoichiometry and rigorous safety controls because of the sensitivity of organic peroxides. High-purity feedstocks and continuous process monitoring reduce unwanted side reactions, ensuring reliable initiator activity for downstream compounders and formulators.

    Industry compliance standards

    • ISO 9001 Quality Management for chemical manufacturing
    • OSHA Process Safety Management for peroxides
    • GHS/CLP Regulation for storage and transport of hazardous materials
    • FDA 21 CFR 177.2420 (for food-contact polymer applications)

    Typical usage ratio

    • 2.0 molar equivalents per mole of hydrogen peroxide in batch synthesis
    • Ratio adjusted for reaction completeness and minimal residual chloride

    Downstream process integration

    • Batch or continuous synthesis in jacketed, temperature-controlled vessels
    • Stagewise addition to prevent runaway reactions
    • Filtration and micronization for delivery to polymerization kettle or compound mixer

    Final product types

    • Benzoyl peroxide paste for composite curing
    • Benzoyl peroxide powders for thermoplastic and thermosetting resins
    • Acrylic emulsions and adhesives
    • Dental bleaching compounds

    3. Production of Agrochemical Intermediates (Herbicide Synthesis)

    The agrochemical sector employs Benzoyl Chloride in the synthesis of key phenoxy and benzoic acid-based herbicide intermediates, such as dicamba and MCPA derivatives. Manufacturers require high assay content and strict control over chlorinated by-products to meet environmental and crop safety regulations. Reactors must enable precise feed control, while downstream purification steps eliminate process residues before formulation into technical grade active ingredients.

    Industry compliance standards

    • FAO/WHO Specification 235/DS for pesticide technical material
    • ISO 9001 and ISO 14001 (Environmental Management) certification
    • REACH Regulation (EU) for chemical safety reporting
    • US EPA active ingredient registration requirements

    Typical usage ratio

    • 1.05–1.12 molar equivalents, depending on substrate hydroxyl content
    • Ratio based on quantitative GC analysis to assure technical specification

    Downstream process integration

    • Charged into acylation stages during the condensation of phenoxyacetic acids
    • Followed by neutralization, extraction, and purification steps
    • Yields concentrated agrochemical intermediates for formulation

    Final product types

    • Technical dicamba (3,6-dichloro-o-anisic acid)
    • MCPA derivatives (phenoxyacetic acids)
    • Other benzoic herbicide active ingredients
    • Post-emergence weed control formulations

    4. Dye and Pigment Synthesis (Azo and Anthraquinone Chromophores)

    Colorant and pigment factories use Benzoyl Chloride for introducing benzoyl functional groups and activating aromatic substrates in the production of vibrant azo and anthraquinone dyes. During the dye coupling and acylation stages, material purity — especially regarding free acid and moisture — affects hue brightness and product stability. Synthetic batches use high-purity reactants with carefully sequenced additions to develop colorfast outputs for coatings, textiles, and plastics.

    Industry compliance standards

    • ISO 9001:2015 for colorant manufacturing
    • Oeko-Tex 100 Annex 4 (for textile applications, banned amines)
    • EN 71-3 for pigments in toys and consumer goods
    • REACH Annex XVII for analytical verification of hazardous contaminant levels

    Typical usage ratio

    • 0.8–1.0 molar equivalents for aromatic acylation in dye intermediates
    • Adjusted based on UV/Vis analytical color endpoint

    Downstream process integration

    • Added during key acylation steps in closed reactors
    • In-line monitoring of reaction progress
    • Subsequent neutralization, filtration, and drying to yield pure chromophore powders

    Final product types

    • Azo dyes for textile and leather finishing
    • Anthraquinone pigments for plastics and paints
    • Specialty organic pigments for printing ink
    • Technical grade colorants for industrial finishes

    5. Fragrance and Flavor Intermediates in Fine Chemicals

    Producers of aromatic aldehydes and esters integrate Benzoyl Chloride to generate benzyl derivatives used as fragrance and flavor precursors. The synthesis typically involves Friedel–Crafts acylation and transesterification in batch reactors. Strict documentation and process analytical controls are required, as food or cosmetic applications introduce extra safety and traceability reliance. Our deliveries support consistent product profiles with validated absence of undesirable residues or solvent contaminants.

    Industry compliance standards

    • IFRA Code of Practice for fragrance ingredients
    • FEMA GRAS list (US), JECFA Guidelines (Codex Alimentarius)
    • US FDA 21 CFR 172 (food additives) and 21 CFR 182 (flavorings)
    • ISO 22716:2007 for cosmetic manufacturing (GMP)

    Typical usage ratio

    • 1.0–1.2 molar equivalents during esterification and acylation reactions
    • Adjusted per analytical titration to achieve specified aromatic content

    Downstream process integration

    • Dosed at Friedel–Crafts acylation stage to obtain benzyl (and substituted benzyl) intermediates
    • Followed by distillation and purification under reduced pressure
    • Quality-controlled prior to blending in final fragrance or flavor batches

    Final product types

    • Benzyl benzoate: fragrance fixative, flavoring agent
    • Benzaldehyde derivatives for fruit and floral notes
    • Cinnamic acid esters for fine fragrance blends
    • Aromatic chemicals for food, beverage, and cosmetic industries

    6. Performance Coatings and Resin Additives

    In specialty resin and surface coatings production, Benzoyl Chloride aids in introducing benzoyl functionalization to enhance UV stability, hardness, and gloss. Manufacturers often employ it in the preparation of alkyd, acrylic, and polyester resins where controlling molecular architecture directly impacts resistance and long-term performance. Batch records emphasize complete conversion with minimal unreacted acid chloride, and product sampling checks for crosslinking performance in target applications.

    Industry compliance standards

    • ISO 9001:2015 for coating system manufacturers
    • ASTM D16 Terminology for Paint, Related Coatings, and Materials
    • EU RoHS and REACH for heavy metal and SVHC control in industrial coatings
    • EN 1504-2 for protective coatings in construction

    Typical usage ratio

    • 0.5–1.0 molar equivalents, depending on backbone polyol content
    • Adjusted based on viscosity and crosslink density targets

    Downstream process integration

    • Metered addition during pre-polymer formation or resin modification stage
    • Followed by chain extension and removal of residual HCl via scrubbing or inert gas purging
    • Sampling for resin acid value and molecular weight distribution

    Final product types

    • Acrylic resins for automotive finishes
    • Anhydride-modified alkyd resins for wood and metal coatings
    • Polyester dispersions used in architectural formulations
    • Industrial protective topcoats
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    Certification & Compliance
    More Introduction

    Benzoyl Chloride: Practical Insights from the Production Line

    Direct from the Source: Our Take on Benzoyl Chloride

    Benzoyl chloride shows up at the core of everyday industry in a way lab textbooks rarely capture. At our manufacturing plant, we see it roll off the reactors every day. From the pungent, unmistakable aroma that fills the air in the processing hall to the careful sampling and testing that defines each batch, there’s no mistaking whether it’s a good run. Successful batches let our partners in pharmaceuticals, polymers, and dyes meet their targets, because this intermediate keeps entire value chains moving forward.

    Specifications Built on Real-World Experience

    We produce benzoyl chloride with a minimum assay of 99%, colorless or sometimes faintly yellow at the highest grades. Any experienced operator in bulk chemicals will tell you how a few stray impurities can throw off downstream reactions. Whether it’s residual benzoic acid or traces of chlorinated byproducts, end users notice quickly. This is why our team monitors every fraction. Real specs aren’t just numbers you find in a reference book—they’re the difference between a product batch that polymerizes as expected and a shipment that stalls at the customer’s quality check.

    Moisture content, for example, needs serious attention. Water in the product—even at trace levels—brings hydrolysis. That forms benzoic acid and hydrochloric acid, and in production that means corroded valves, fouled pipes, and a bad smell that lingers long after the drum is emptied. Our filling lines run with nitrogen blanketing, and we seal packaging immediately on fill, keeping product dry from line to drum. To cutting costs by skipping these steps is to risk downtime and lost business, and we’ve learned this firsthand through hard-earned lessons over the years.

    Applications: A Closer Look Beyond Textbook Use

    It’s easy to gloss over what benzoyl chloride does, but on the factory floor, its roles are plain to see. In the pharmaceutical industry, our customers rely on its acylating ability to synthesize benzoyl derivatives for drugs, from antihistamines to antibiotics. They depend on it for purity and batch consistency. A five-figure block of drug substance can fall out of spec thanks to a contaminated intermediate, and the stakes are high for both patient safety and regulatory compliance.

    In agrochemicals, benzoyl chloride permits the creation of benzamide and benzoate structures necessary for modern pesticides. We watch the agricultural cycle closely, since growing seasons directly affect our demand. In the world of perfumery and dyes, its reactivity lets chemists build colorants and fragrances that withstand sunlight and sweat. Water treatment and photoinitiators for UV-cured coatings likewise call for steady supply and tight quality control.

    Each application tells us something about handling and purity. Pharmaceutical customers have no interest in visible color or off-odor. Dye and pigment producers running continuous processes want drums that don’t bake in the sun and degrade their raw materials in transit. Over many years, we have adjusted filtration, packing, and dispatch routines to avoid these headaches, learning where shortcuts lead and how to avoid mixing issues that cause downstream chaos.

    Real Differences: Benzoyl Chloride Versus Other Acyl Chlorides

    Few intermediates compete directly with benzoyl chloride, but acyl chlorides share some basic handling hazards. Acetyl chloride, for example, is lighter and more volatile, with a tendency to drift off and hydrolyze even in damp air. That makes it harder to keep stable in bulk storage. Benzoyl chloride runs heavier, with a higher boiling point and less vapor loss, so it moves better in bulk transfer setups.

    In reactions, our in-house trials and countless customer feedback rounds show that benzoyl chloride’s selective reactivity gives more predictable yields in Friedel–Crafts acylations and amidations. This matters for consistency, because plant operators dislike reaction chains with a mind of their own. Suppliers who switch out benzoyl chloride for alternatives often find shifts in product properties downstream—a difference evident in yields, color, or purification demands.

    We take pride in offering a product that fits high-pressure continuous reactors as reliably as it does in small-batch development labs. Not all acyl chlorides can say the same. Bulk users in resin and coating industries report trouble with lower-boiling substitutes, especially where plant design gives room for fugitive emissions. We spent years tweaking our production and packaging for these realities, making sure our product behaves as needed regardless of process scale.

    Handling: Practical Know-How from Plant to Warehouse

    Every container of benzoyl chloride demands real respect. Staff in our plant suit up in chemical resistant gear daily, and our packaging team has encountered every scenario from sweating drums in a humid summer to emergency venting after poor storage elsewhere. There’s a right way and a wrong way to handle this product, and we’ve seen both.

    In the plant, we install acid scrubbers and dry nitrogen purges to control fumes and prevent contact with water. When loading and unloading, our crew checks seal integrity with visual inspections and pressure checks. Bulk tank transfers require constant supervision, not just for regulatory reasons, but because we know from experience that one slip-up creates a persistent odor and corrosion problem in a matter of minutes.

    Transportation is another focus. We’ve tailored drum liners and use high-density polyethylene or steel drums, always checking for compatibility with aggressive acyl chlorides. Over the years, we have seen leakers from neglected old barrels teach costly lessons. Our operations crew learned to document every batch’s chain of custody, and we engage with logistics partners who understand why late delivery in hot weather spells disaster for this product.

    Emergency response isn’t theoretical. We run real drills with our staff: cleaning hydrolyzed spills, neutralizing acidic vapor clouds, and disposing of contaminated packing safely. Our locality partners respect our preparedness and we teach our processes to every new hire. This dedication comes from years of practical experience and a real understanding that safety is not a box on a checklist.

    Market Pressures, Real Costs, and the Road Ahead

    Benzoyl chloride production often reacts to global shifts faster than some might expect. Sharp spikes in chlorination costs, stricter emissions regulations, and cross-border logistics hurdles all impact product availability. Over the last decade, supply constraints from upstream benzene price swings and environmental crackdowns have squeezed both margins and delivery reliability. In years with more trade restrictions, capacity in one region dries up and global spot prices jump.

    We keep close ties to our benzene and chlorine suppliers, working relationships years in the making. Experienced purchasing teams on both sides compare notes not just on price, but also on purity, annual contracts, and plant reliability. We avoid the temptation to chase every short-term market win, preferring to invest in our own plant improvements and client retention. Delivering on time and in full brings more value over the years than gambling on volatile price spikes.

    Keeping pace with regulatory changes is another task we face head-on. Benzoyl chloride is classified as hazardous not without reason—improper handling causes public health and environmental incidents. We invest every year in emissions controls and train our operators in accident response. Our facilities are regularly audited by local authorities, and we welcome honest critique. These safeguards come as an added cost, but any manufacturer serious about long-term survival chooses compliance and ethical practices over cut corners.

    Customers remind us why these steps matter. Downtime on a downstream product line over tainted intermediates means lost production, late shipments, and a scramble to find solutions. Years of feedback taught us where weak points exist, and so we build each improvement into the process: tighter loading supervision, smarter sampling, faster response to out-of-spec notifications. The cycle of continuous improvement isn’t an abstract idea—it’s a habit grounded in respecting every customer.

    Sustainability, Innovation, and Responsible Growth

    In our corner of the chemical industry, sustainability is less about public relations and more about day-to-day survival. We invest in scrubbing emissions, recycling byproduct hydrogen chloride, and optimizing our chlorination efficiency, so less raw material ends up as waste. Teams on the production floor make suggestions for process tweaks, and many of their ideas have prevented untold gallons of off-spec or waste product from ever leaving the plant.

    New regulations mean that future benzoyl chloride plants must adapt. Pressure for lower emissions and greener chemistry continues to grow. We follow research into alternative acylating agents and reactivity modifiers closely. For now, few substitutes match the balance of cost, reactivity, and supply reach that benzoyl chloride offers. Our approach is to participate in industry consortia, review our own impacts critically, and upgrade as technology allows. We avoid greenwashing and talk straight with our clients about what we are doing and what problems still need answers.

    Digital systems also play their part. Sensor networks in our storage yards warn when drum temperatures start to move out of the safe range, and digital inventory systems help spot potential delivery bottlenecks before they cascade into stockouts. This kind of data-driven vigilance didn’t exist a decade ago, but today it gives us the edge in preventing the old problems—spoiled drums, lost shipments, and unexpected shortfalls—that used to plague the industry. Our own operational experience underscores how a few hours of rapid intervention often prevent a whole chain of downstream complaints.

    Choosing Benzoyl Chloride: Why Producers and Engineers Return Year After Year

    Customers choosing our benzoyl chloride aren’t shopping for the lowest number on a quote sheet. They seek partners who know the difference between commodity trading and responsible production. We’ve had clients share their own plant stories over the years—missed production quotas, regulatory fines, or customer complaints—because the basic building blocks didn’t show up to specification. In each case, we sat down and dug into batch records, shipment logs, and storage conditions until every question was answered and problems traced back to the root.

    Some return because we stick by repeatable quality, shipment after shipment. Some value that they see the same names and faces dealing with orders and questions, not a revolving door of unfamiliar sales reps or distant intermediaries. We believe the real backbone of specialty chemicals is not only about technical data—though that always matters—but about trust built on years of experience making and shipping the material itself. Each improvement, each new process tweak, comes from hard days spent problem-solving, not from theory or generic copy.

    What our plant crews understand is that manufacturers bear the weight of market swings, regulatory tightening, and ever-increasing performance expectations. Benzoyl chloride isn’t forgiving. It shows up the weaknesses in your supply chain, your storage protocols, and even your staffing. We know this firsthand because we have worked through every season of the market downturn, regulatory surprise, and technical hiccup.

    Every person who handles, packs, ships, or stores benzoyl chloride at our sites understands the risks and rewards of a well-run operation. These lessons aren’t found in brochures. They grow out of production mishaps, crisis calls from a customer site, and late-night troubleshooting sessions when specifications don’t line up. That’s how we keep building not just a reputation, but a non-stop cycle of learning and improvement that helps both our own team and every customer who comes to us.

    Practical Solutions to Persistent Challenges

    Bottlenecks in benzoyl chloride supply lines regularly trace back to overlooked basics: moisture ingress, delayed shipments, or misunderstood packaging limits. We have spent years retraining loading operators after summer storms, refining moisture-barrier packaging, and working with logistics firms who invest in their own staff training. Every improvement comes out of a root-cause analysis, never a guess or shortcut.

    Short-term fixes, like pushing shipments out the door with minimal checks or relying on subpar containers, never pay off over time. They simply defer problems downstream, usually onto the same team that tried to cut corners in the first place. Our philosophy turns on attention to detail at every stage, from bulk storage maintenance to inventory rotation that cuts the chance of old drums swelling. Regular plant audits, ongoing operator training, and even simple steps like consistent labeling and batch tracking offer outsized returns in reliability.

    Major clients often ask about process changes or suggested efficiencies. Sometimes these are worth considering—adjusting a filtration step for a new application, tweaking synthesis rates for a large order, or co-investing in new transport equipment. Through experience we’ve learned to weigh the upfront investment against the recurring headaches of breakdowns, poor yields, or recurring non-conformance. We share research findings openly and build practical solutions together, rather than leaning on buzzwords or masking problems.

    Downstream, we advocate for open communication. If a customer’s application changes or new impurity limits arise, we encourage rapid feedback, so we can tweak production or handling before those challenges snowball. Sharing data, test results, and experience builds resilience on both sides, making crisis response smoother and partnerships more secure.

    Trust Forged in the Realities of Chemical Manufacturing

    What separates one benzoyl chloride supplier from the rest isn’t just technical data but hard-won reliability that comes from daily production realities. We never stop adjusting procedures, questioning old habits, and investing the time to perfect each shipment. Our customers teach us something new every year, whether it’s a subtle shift in regulatory compliance, a new loading protocol that saves hours, or a lesson learned from a close call with moisture exposure.

    Benzoyl chloride is demanding: it reveals weaknesses fast but rewards careful stewardship over time. We are proud of the long-term relationships we have built on the back of experience, accountability, and genuine care for both product and people. Each drum and each tanker tells a story of the hard work, knowledge, and perseverance that go into making quality possible, shipment after shipment.

    This grounded approach to benzoyl chloride, shaped by people who live the realities of its creation every day, informs how we do business, support our customers, and keep pushing forward in an ever-changing chemical world. Our commitment stands: value built from experience, practical improvement, and steady trust—qualities you can depend on in every drum that leaves our plant.