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Actinomycin

    • Product Name Actinomycin
    • Alias Dactinomycin
    • Einecs 200-063-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    789274

    Generic Name Actinomycin
    Other Names Dactinomycin
    Drug Class Antineoplastic antibiotic
    Chemical Formula C62H86N12O16
    Molecular Weight 1255.42 g/mol
    Mechanism Of Action Inhibits DNA-dependent RNA synthesis
    Route Of Administration Intravenous
    Therapeutic Uses Cancer chemotherapy (Wilms tumor, rhabdomyosarcoma, testicular cancer, Ewing’s sarcoma)
    Appearance Orange-yellow crystalline powder
    Storage Conditions Store at 2°C to 8°C (refrigerated)
    Solubility Slightly soluble in water, freely soluble in methanol
    Cas Number 50-76-0

    As an accredited Actinomycin factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for Actinomycin features a sealed amber glass vial containing 5 mg of lyophilized powder, labeled with handling instructions.
    Shipping Actinomycin is shipped as a hazardous substance under regulated conditions. It must be securely packaged in leak-proof, labeled containers and transported at controlled room or cold temperatures, as per safety and regulatory requirements. Shipping involves compliance with IATA, DOT, and other guidelines to ensure safe, compliant delivery and protection from light and moisture.
    Storage Actinomycin should be stored at 2–8°C in a tightly closed container, protected from light and moisture. The chemical should be kept in a designated, well-ventilated chemical storage area, away from incompatible substances. For long-term storage, refrigeration is recommended to maintain stability. Proper labeling and secure containment are essential to avoid contamination or accidental exposure, as Actinomycin is hazardous.
    Application of Actinomycin

    Purity 98%: Actinomycin with a purity of 98% is used in oncology research, where it ensures reliable inhibition of RNA synthesis for cytotoxicity evaluation.

    Molecular weight 1255.45 Da: Actinomycin with molecular weight 1255.45 Da is used in gene expression studies, where it provides consistent transcriptional blocking efficiency.

    Melting point 225°C: Actinomycin with a melting point of 225°C is used in formulation stability testing, where it allows for thermal stability under processing conditions.

    Stability temperature 2-8°C: Actinomycin with a stability temperature range of 2-8°C is used in extended storage protocols, where it maintains biological activity over prolonged periods.

    Solubility in water 0.5 mg/mL: Actinomycin with solubility of 0.5 mg/mL in water is used in in vitro assay preparations, where it facilitates homogeneous solution preparation for accurate dosing.

    Light sensitivity high: Actinomycin with high light sensitivity is used in photosensitivity assessments, where it demonstrates the need for protected handling to preserve activity.

    Endotoxin level <0.1 EU/mg: Actinomycin with endotoxin level less than 0.1 EU/mg is used in cell culture applications, where it reduces the risk of endotoxin-induced effects on cell behavior.

    pH stability range 5-7: Actinomycin with a pH stability range of 5-7 is used in buffer optimization studies, where it ensures consistent molecular integrity during experimental procedures.

    Particle size <10 µm: Actinomycin with particle size less than 10 µm is used in injectable formulation development, where it promotes uniform dispersion and accuracy in dosing.

    HPLC assay ≥99%: Actinomycin with HPLC assay of 99% or higher is used in pharmaceutical quality control, where it assures product purity and compliance with regulatory standards.

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