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HS Code |
286982 |
| Cas Number | 603-87-8 |
| Molecular Formula | C8H9NO2 |
| Molecular Weight | 151.17 g/mol |
| Iupac Name | 1,3-dimethyl-5-nitrobenzene |
| Appearance | Yellow crystalline solid |
| Melting Point | 52-54 °C |
| Boiling Point | 261-263 °C |
| Density | 1.16 g/cm³ |
| Solubility In Water | Insoluble |
| Refractive Index | 1.571 |
As an accredited 5-Nitro-1,3-Xylene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 250g amber glass bottle with a screw cap, labeled “5-Nitro-1,3-Xylene,” featuring hazard symbols and product details. |
| Shipping | **Shipping for 5-Nitro-1,3-Xylene** should comply with local, national, and international regulations. The chemical must be securely packaged, properly labeled as hazardous, and accompanied by a Safety Data Sheet (SDS). It should be shipped in tightly sealed containers, away from incompatible substances, and transported by certified carriers authorized to handle hazardous materials. |
| Storage | 5-Nitro-1,3-xylene should be stored in a tightly sealed container, in a cool, dry, well-ventilated area away from heat, open flames, and direct sunlight. Keep it separate from incompatible substances such as oxidizers and strong acids. Store at room temperature and avoid moisture. Clearly label all containers, ensure secondary containment, and follow all relevant safety and regulatory guidelines for storage. |
Applications of 5-Nitro-1,3-Xylene in Industrial Manufacturing5-Nitro-1,3-Xylene serves as a key intermediate for multiple downstream chemical industries, particularly within advanced dye synthesis, agrochemical intermediates, and specialized polymers. The following application scenarios reflect current, field-validated end-use sectors and specific integration into manufacturing processes, including regulatory, operational, formulation, and commercial contexts. 1. Synthetic Dye and Pigment Intermediates for Textile and Leather IndustryAs a nitrated aromatic compound, 5-Nitro-1,3-Xylene functions as a direct intermediate in synthesizing azo and anthraquinone dyes, widely utilized in textile and leather coloration. Downstream manufacturers optimize coupling and diazotization protocols, relying on the high purity of incoming nitro-xylene to achieve consistent color strength and fastness. Stringent effluent controls and by-product management remain crucial to meet industrial discharge standards during scale-up, particularly during subsequent hydrogenation and coupling steps. Industry compliance standards
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2. Agrochemical Intermediate for Herbicide SynthesisDownstream agrochemical manufacturers use 5-Nitro-1,3-Xylene in multi-step syntheses of heterocyclic herbicides and crop protection ingredients. Its nitro functionality permits selective nitration followed by cyclization, contributing to molecular structures with targeted weed suppression capabilities. Stringent monitoring and traceability requirements apply due to the regulatory context of pesticide manufacturing, especially with regards to intermediates bearing nitroaromatic structures, governed by both domestic and international standards to control residuals and environmental release. Industry compliance standards
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3. Pharmaceutical Intermediate in Antimicrobial API SynthesisManufacturers of antibacterial agents employ 5-Nitro-1,3-Xylene as a functionalized aromatic starting material in the synthesis of nitroaromatic drug intermediates, particularly for the preparation of certain nitrofuran and nitroimidazole APIs. Strict in-process monitoring is mandatory due to bioactive residue thresholds, and handling procedures require validated cleaning and segregation protocols under GMP systems. The process must maintain low impurity profiles and strict batch traceability in line with market authorization and pharmacopoeia submission requirements. Industry compliance standards
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4. Precursor for High-Performance Polymer AdditivesCompanies engaged in specialty plastics and coatings manufacture utilize 5-Nitro-1,3-Xylene within the synthesis of performance-boosting polymer additives. Its structure allows integration into plasticizer or UV-absorber compounds, imparting enhanced stability to engineering polymers and coatings under UV exposure and high temperatures. Applications particularly target electronic and automotive components, where compliance with precise performance and regulatory standards is critical for final commercial acceptance. Industry compliance standards
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5. Intermediate in Rubber Chemical Synthesis5-Nitro-1,3-Xylene enters the industrial rubber sector as a critical step intermediate in synthesizing antioxidant and antiozonant chemicals. These downstream chemicals extend the service life of rubber goods, especially in tire and belt manufacturing, by inhibiting degradation from ozone, UV light, and oxygen exposure. Manufacturing processes in this sector prioritize formulation traceability as well as compliance with international safety, migration, and toxicity limits set for rubber articles and automotive goods. Industry compliance standards
Typical usage ratio
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For decades, chemists in our plant have kept their focus on getting the details right. Small adjustments in the addition rates, constant monitoring of temperature during nitration, and careful purification—these steps define the difference between a clean batch and one the team rejects. Producing 5-Nitro-1,3-Xylene isn’t a matter of following steps by rote. Each run asks us to bring technical judgment and the discipline that only experience in chemical manufacturing supplies. We see what works by looking at every dataset from every batch, from color values to impurity profiles. The result: a material relied on by industries that value consistency as much as chemistry.
Every batch of 5-Nitro-1,3-Xylene manufactured here comes from a tightly controlled process, using refined xylenes as a base. Quality starts with raw material; we screen incoming xylene for the right isomeric ratios and minimal contaminant load. We’ve seen how shortcutting any of these preliminary steps affects downstream color and odor, which can, in turn, alter how end-users apply the product, especially in pigment or dye synthesis. With decades running continuous and batch nitration lines, our team has learned not to take raw material purity for granted. It affects everything that follows.
From the moment nitric and sulfuric acid meet the xylene feed, everything depends on precise control. The nitration creates a mixture of products, but our process focuses on maximizing output of the meta isomer, which directly gives 5-Nitro-1,3-Xylene. Isolation requires vigilant fractionation and constant analytical checks—our in-line GC and HPLC systems catch subtle spikes in by-products before these reach a level that triggers rework or scrap decisions. Over the years, tweaking the workup and purification has led to improvements in particle behavior, reduced color bodies, and a product that handles consistently in downstream synthesis. Through all of this, hands-on know-how matters as much as automated control. A few tenths of a degree make the difference and trained eyes spot inconsistencies that machines do not.
Our 5-Nitro-1,3-Xylene comes out as a pale yellow solid, typically shipped in drums or bags suited for the customer’s operation scale. Moisture content runs low—routine Karl Fischer titrations demonstrate values under 0.2% as a matter of course. This may seem trivial, but we know from customer feedback how excessive moisture can interfere with finely balanced chemical syntheses or storage stability. As nitrated aromatics go, our product runs to a melting point well matched to published values, which points to minimal contamination by higher or lower melting by-products. Even a single batch drifting outside accepted temperature range prompts immediate root cause analysis; no one here wants a production run held up by a slight process slip.
We pay close attention to the odor profile. A faint aromatic character signals a well-made lot. Residues of dinitro derivatives or unreacted material produce unmistakable off-notes. Our QA averages over 20 analyses on a single lot before shipping any significant volume. Laboratory and production teams know what a good product smells and appears like; it’s part of the accumulated knowledge base. It’s routine to see chemists taking quick melting point samples off daily output and running them alongside standard references from past high performers. Over time, this habit builds confidence that each batch meets the standards we aim for, and our partners in downstream processing notice the difference.
5-Nitro-1,3-Xylene has carved out roles in dye manufacturing and specialty chemical synthesis. As a key intermediate, it bridges simpler aromatic chemistry and high-value pigments, plasticizers, or specialty agents in agricultural formulations. Our clients treat it as more than just a reagent—it’s a piece of a larger puzzle in color formulation, polymer modification, and complex molecule construction. In dye synthesis, for instance, 5-Nitro-1,3-Xylene acts as a stable platform for further substitutions, enabling the creation of vivid, durable colors desired in printing inks and specialized tapes. Our technical liaisons work with clients’ R&D groups to optimize reactivity, solubility, and compatibility, often running side-by-side application trials and jointly troubleshooting anomalous results.
In polymers, 5-Nitro-1,3-Xylene finds use as a monomer modifier or in cross-linking schemes. Years ago, several partners in the plastics sector faced issues with batch-to-batch variances that threw off polymerization rates. By working directly with their technical specialists, adjusting our purification protocols, and providing consistent certificates of analysis, these issues dropped off. That interaction taught us the true value of listening to partners, because laboratory reality sometimes runs counter to textbook expectation.
Scaling nitration of aromatics looks straightforward on paper, but in reality, seasoned operators watch for subtle cues that raw data can’t always reveal. The stability of the mixed acid layer, foaming behavior, or color shifts in washed product each hint at deeper process issues. Years spent troubleshooting everything from acid carryover to uncharacteristic exotherms have shaped procedures that keep our output predictable and, more importantly, safe. This isn’t just about internal metrics—it bears directly on the product performance further down the supply chain.
Often, our customers come to us referencing a specific color index number or a critical impurity threshold. We respond not simply by reading a spec sheet, but by drawing on every recorded instance where that requirement clashed with process limitations then solving it through small, deliberate process changes. Every new requirement teaches us something, and each fix becomes part of our standard operating procedure. Whether it’s tuning droplet size in extraction or extending water wash times, these changes ripple outward, delivering the reliability that our partners depend on.
Many aromatic nitro compounds circulate through industrial chemistry, but having processed them side by side, we’ve observed practical differences. 5-Nitro-1,3-Xylene delivers better performance in reactions demanding a meta-positioned nitro group—not just for steric reasons, but because it proves less reactive under accidental reduction and shows cleaner product profiles compared to ortho or para analogs. In pigment synthesis, this is critical; side reactions from other isomers introduce unwanted color notes and drop fastness. We back these observations with both production experience and published literature—side-by-side analyses done in our lab have shown yield boosts and cleaner filtrate profiles when customers switch from mixed nitroxylene grades to our high-purity 5-Nitro-1,3-Xylene.
Comparative testing also revealed storage advantages. While some nitroaromatics can pick up minor discoloration or caking in storage, our process yields a crop that remains free-flowing and keeps color within narrow limits. This cuts losses caused by reprocessing material that fails appearance or handling checks. Our packaging line keeps moisture below the threshold where clumping occurs, giving our partners more time and flexibility in managing inventory.
Other xylene-based nitro products may offer advantages depending on the target chemistry, but they rarely capture the same balance of reactivity, physical stability, and cost efficiency. We often discuss these trade-offs openly with downstream chemists searching for ways to substitute materials, making sure that practicality takes precedence over theory. In several cases, shifting to 5-Nitro-1,3-Xylene has delivered process efficiency or simplified waste management due to its cleaner reaction profile.
We believe years of consistent supply matter more than any stack of technical claims. Any minor disruption in schedule—an errant drum, an unexpected color change—triggers rescheduling in our customers’ operations, which reverberates through their processes and, ultimately, the products their clients receive. By keeping a tight grip on our own maintenance, raw material vetting, and in-process testing, we stand behind our commitments. The discipline of preventative maintenance in the plant—the habit of testing not just final product, but every intermediate as it runs—keeps both reliability and product purity on target.
Past experience with force majeure events, unforeseen regulatory changes, and supply chain shocks has taught us all the importance of stocking raw materials, judicious scheduling, and keeping backup utilities. Each time circumstances force a change, the plant teams regroup, sort through delivery schedules and production forecasts, and ensure finished goods keep flowing. It’s not just about avoiding lost sales—it’s about keeping trust with partners who rely on our product for their own manufacturing. Our job means managing the details, always with the end use in mind.
Research and development groups at our clients value predictability, but sometimes they push the boundaries of how 5-Nitro-1,3-Xylene serves their formulas. We often get calls or emails from chemists running new reactions or scaling bench work to pilot scale. Sharing what we’ve seen at commercial scale—such as how subtle changes in acidity influence side formation, or which solvents minimize waste—helps our partners avoid dead ends. Our technical staff shares observations, even from “near-miss” batches or off-spec runs, when those details carry lessons for ongoing work. This ongoing exchange with formulation chemists and process engineers helps push synthetic chemistry forward while avoiding unnecessary risk.
From time to time, our R&D group gets direct feedback about troublesome reaction sequences. These real-world stories shape next-generation product lines and even inspire incremental tweaks to bulk process streams. In one recent case, a customer’s need to cut out certain trace amines led us to refine a step in water washing, which, after much trial and error, now gives lower impurity spikes and smoother blending downstream. This is the essence of chemical manufacturing as we practice it—always tuning, always adapting, never done learning from experience.
Shelf life, regulatory compliance, and analytical verification—these are reality, not paperwork. Our QC program traces every lot, not just to the critical process stages, but right down to the hourly logs of physical properties. Maintaining this discipline means anyone in our operation can answer questions with facts, not guesswork. Year after year, regulatory audits pass routinely. Wherever new industry requirements or local regulations emerge, we adapt processes rather than looking for shortcuts. Sometimes those changes challenge established workflows, but institutional knowledge in the plant guides the best way forward.
We know that information transparency is now the expectation, not a bonus. Customers ask for full impurity disclosure, storage data, and origin tracking, and we provide it—sometimes going beyond what the letter of the law requires. The value of an open, evidence-driven approach shows itself every time a customer parses another supplier’s ambiguous analysis and then finds ours straightforward and detailed.
Handling nitrated aromatics comes with challenges—safety, accident prevention, and responsible waste management top the list. Our staff receives extensive training, not just on standard protocols, but through drills and scenario planning. Over a decade of production, we’ve reduced process water acidification and captured more spent acids for recycle, streamlining both cost and environmental impact. Fume management and personal protective measures build upon continual monitoring, with every process upgrade targeting both emission drops and worker comfort. At every annual audit, results show falls in hazardous waste output and process losses.
On the product side, lower residual acid levels and a firm grasp on dust and vapor mitigation keep our clients’ facilities safer and less prone to runaway incident risk. For partners needing help with safe handling and fire prevention, our plant engineers advise on best practices grounded in what works at scale, avoiding theoretical advice in favor of tested solutions. No one wins by hiding flaws or downplaying risks—clear dialogue about process hazards and how we cope with them offers the best learning ground for improvement throughout the industry.
This compound remains a vital cog in the machinery of specialty chemicals, dyes, and plastics. We see its central role only expanding as industries demand both reliability and greater environmental care from their materials. Within our own operation, plant upgrades and automation projects target lower resource use and higher purity output—but we never lose sight of the hands-on skills that matter for true process mastery. New regulations arrive, supply chains grow more complex, but our focus holds steady on delivering what customers need.
Each year brings technical and practical questions about how 5-Nitro-1,3-Xylene can better fit evolving applications. Instead of treating these as hurdles, we welcome the collaboration. Our door stays open to any customer or partner looking for practical, field-tested knowledge about making the most from their chemical inputs. Reliability, safety, and adaptability—these values shape how we make 5-Nitro-1,3-Xylene and how we support our partners across the world. The story of this compound is, in many ways, the story of tireless, behind-the-scenes progress that keeps both industries and the products everyone counts on moving forward.