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4-Phenyl-1-Butene

    • Product Name 4-Phenyl-1-Butene
    • Alias 4-Phenyl-1-butylene
    • Einecs 211-130-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    546541

    name 4-Phenyl-1-Butene
    cas_number 104-67-6
    molecular_formula C10H12
    molecular_weight 132.20 g/mol
    appearance Colorless liquid
    boiling_point 193-195 °C
    melting_point -87 °C
    density 0.91 g/mL at 25 °C
    refractive_index 1.531
    flash_point 78 °C
    solubility_in_water Insoluble
    pubchem_cid 7495

    As an accredited 4-Phenyl-1-Butene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500 mL amber glass bottle with screw cap, chemical label displaying "4-Phenyl-1-Butene," hazard warnings, and manufacturer details.
    Shipping 4-Phenyl-1-Butene is shipped in tightly sealed containers under ambient conditions. It should be stored in a cool, well-ventilated area away from sources of ignition. Transport must comply with local, national, and international regulations for flammable liquids. Appropriate hazard labeling and documentation are required to ensure safe handling during transit.
    Storage 4-Phenyl-1-Butene should be stored in a cool, dry, well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizers. It should be kept tightly sealed in a chemically resistant container, protected from light and moisture. Proper labeling is essential, and access should be limited to trained personnel using appropriate personal protective equipment.
    Application of 4-Phenyl-1-Butene

    Applications of 4-Phenyl-1-Butene in Industrial Manufacturing

    4-Phenyl-1-Butene is a key specialty olefin used as a building block in the production of advanced materials and performance chemicals across multiple industrial sectors. As a direct manufacturer, we supply this compound to global clients involved in established value chains where reliability, traceability, and compliance with stringent industry protocols are essential. The following application scenarios highlight specific downstream pathways where this material enables the synthesis of differentiated end products under compliance with current international standards.

    1. Pharmaceutical Intermediate Synthesis

    Pharmaceutical manufacturers use 4-Phenyl-1-Butene as a crucial intermediate in the multi-step organic synthesis of active pharmaceutical ingredients, particularly in the development of cardiovascular agents and certain antihypertensive compounds. The compound introduces a phenylbutyl moiety, facilitating later-stage functionalization via hydroformylation, oxidation, or amination. Precise control of input ratios and contaminant tracking is required to meet regulatory batch traceability and to prevent by-product formation influencing API purity profiles.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • European Pharmacopoeia Monograph 2034
    • United States Pharmacopeia (USP) compliance (for APIs)
    • FDA 21 CFR Part 211 for finished pharmaceuticals

    Typical usage ratio

    • Utilized at 0.2-2.3 molar equivalents relative to the specific API precursor, adjusted according to reaction yield efficiency and desired batch scale.

    Downstream process integration

    • Fed into Grignard, hydroformylation, or Friedel-Crafts alkylation stages as the key alkene source after pre-activation and solvent conditioning.

    Final product types

    • Cardiovascular pharmaceuticals (e.g., β-blockers, angiotensin receptor antagonists)
    • Antihypertensive agents
    • Structure-validating pharmaceutical intermediates

    2. Synthesis of Aromatic Resin Monomers

    Specialty resin producers implement 4-Phenyl-1-Butene as a functionalized monomer or comonomer in the synthesis of aromatic resins for adhesives, coatings, and high-performance thermosets. By introducing phenylalkyl linkers, manufacturers tune the balance of rigidity and flexibility in the final polymer matrix. Additive ratios require optimization against viscosity control, shelf stability, and downstream reactivity in catalytic copolymerization operations.

    Industry compliance standards

    • ISO 9001:2015 Certified Quality Management for Chemical Manufacturing
    • REACH (EC 1907/2006) compliance for EU imports
    • BGBl. I S. 436, German Chemicals Act safety documentation
    • ASTM D4242 for monomer purity in resin production

    Typical usage ratio

    • Added at 0.5–7.0 wt% in prepolymer blends, with ratio fine-tuned to meet target molecular weight and glass transition temperature based on application demand.

    Downstream process integration

    • Incorporated during the prepolymerization feed of bulk, solution, or emulsion polymerization reactors under inert gas atmospheres to prevent oxidation.

    Final product types

    • Solvent-resistant epoxy resins
    • Aromatic polyurethane adhesives
    • Film-forming binder systems for specialty coatings
    • Cross-linked phenolic engineering plastics

    3. Production of Fragrance and Flavor Intermediates

    The compound serves as a chain-elongating intermediate for the synthesis of fragrance and flavor ingredients within the specialty chemicals sector. Through controlled olefin functionalization, downstream manufacturers convert it into high-value molecules with sweet, floral, or woody notes for use in consumer products. The processing stages require precise stoichiometry to maintain consistency in olfactory character and meet food safety and allergen declaration standards.

    Industry compliance standards

    • IFRA (International Fragrance Association) Code of Practice
    • FDA 21 CFR 172.515 (Flavoring Substances and Adjuvants, US)
    • EU Food Additives Regulation 1334/2008 (for flavorings)
    • ISO 9235:2013 (Aromatic Natural Raw Materials and Derivatives)

    Typical usage ratio

    • Charged at 1–8% content in the catalytic functionalization mixture, with adjustment for target concentration and product yield in batch or continuous syntheses.

    Downstream process integration

    • Introduced at the initial hydroformylation or alkylation stage, enabling side-chain extension before further oxidation or esterification to form desired perfumery ingredients.

    Final product types

    • Musk- and amber-type synthetic fragrances
    • Alkyl-substituted benzene flavor compounds
    • Aromatic alcohols for fine fragrance blends

    4. Advanced Polymer Additive Manufacturing

    Manufacturers producing specialty thermoplastics and elastomers employ 4-Phenyl-1-Butene as a functional chain modifier to improve polymer processing performance and end-use mechanical properties. The compound acts as a reactive diluent or impact modifier, introducing aromaticity and controlled flexibility. Addition levels are carefully set to influence melt index, stress resistance, and product clarity, complying with precise input specifications of technical compounders.

    Industry compliance standards

    • ASTM D1238 for melt flow index testing
    • ISO 1133 for thermoplastics – Flow rates of melted materials
    • RoHS (EU Directive 2011/65/EU) substance restrictions
    • UL 94 Flame Class (where applicable)

    Typical usage ratio

    • Introduced at 0.1–4.5 wt% based on the specific polymer system, adjusted for target tensile strength, elasticity, and optical parameters as specified in formulation tables.

    Downstream process integration

    • Dispensed directly into extruder or compounding mixer prior to pelletizing, with in-line monitoring for consistent dispersion and reactivity with the backbone polymer.

    Final product types

    • High-impact polystyrene (HIPS) compounds
    • Polyolefin-based automotive trims
    • Flexible packaging films
    • Technical thermoplastic masterbatches

    5. Synthesis of Fine Chemical Intermediates for Agrochemicals

    Agrochemical formulators utilize 4-Phenyl-1-Butene as a precursor for generating specialty intermediates used in the construction of select herbicides and plant growth regulators. The structure offers unique accessibility for catalytic functionalization, facilitating the assembly of molecules with controlled volatility and targeted bioactivity. Production operations require validated handling and precise feed rates to maintain product identity and meet agrochemical quality requirements.

    Industry compliance standards

    • FAO/WHO Joint Meeting on Pesticide Specifications (JMPS)
    • ISO 9001 for agrochemical manufacturing
    • REACH Annex II for substance safety information
    • EPA 40 CFR Part 158 (US) for pesticide chemical data requirements

    Typical usage ratio

    • Metered in at 0.3–5.0 mol% related to active compound synthesis, inlet amount set by stoichiometry and reaction selectivity demands.

    Downstream process integration

    • Introduced in the initial alkylation or cross-coupling step for fine chemical intermediate assembly ahead of subsequent derivatization and formulation.

    Final product types

    • Phenylbutyl-substituted herbicides
    • Growth-modulating plant regulators
    • Crop protection intermediate blends

    6. Synthesis of Surfactant Precursors

    4-Phenyl-1-Butene is incorporated by oleochemical manufacturers as an aromatic hydrophobe precursor in the synthesis of specialty nonionic and anionic surfactants. Its controlled incorporation regulates surface tension properties and compatibility profiles in applications requiring robust solubilizing power and performance under harsh conditions. Accurate measurement and integration into sulfonation or ethoxylation processes determine the structure–performance relationship critical to finished surfactant quality.

    Industry compliance standards

    • OECD Guidelines for the Testing of Chemicals
    • ISO 9001:2015 for chemical specialty manufacturing
    • EU Detergents Regulation (EC No 648/2004)
    • Globally Harmonized System (GHS) for labeling and safety

    Typical usage ratio

    • Blended in at 1.5–6.0% w/w of the hydrophobe component, determined by the desired HLB value and target end-use sector (industrial, institutional, consumer).

    Downstream process integration

    • Dosed at the alkylation or ethoxylation reactor feed, with real-time process analytical technology (PAT) controls for chain length and aromatic substitution degree.

    Final product types

    • Nonionic surfactants for metal cleaning solutions
    • Anionic surfactant bases for emulsifiers
    • Aromatic-structured detergents
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    Certification & Compliance
    More Introduction

    Introducing 4-Phenyl-1-Butene: A Versatile Platform Chemical

    Direct from the Factory Floor

    4-Phenyl-1-Butene stands out in specialty chemicals, but for us as the team that actually synthesizes, purifies, and drums this material, it’s not only about its chemical structure. We have followed the production of this molecule from the first raw material delivery to the final QC inspection. In our shop, 4-Phenyl-1-Butene goes by CAS number 104-67-6, though the work begins long before any shipping label gets printed. Our technical staff built up the confidence to scale it to industrial amounts, not just lab samples. Each batch gets run through chromatography, GC purity checks, moisture tests, and every step in between. Over time, that kind of repetitive care brings out a clear sense for the features that really matter to end users in both research and manufacturing.

    What Makes 4-Phenyl-1-Butene Distinct

    In terms of structure, 4-Phenyl-1-Butene blends a straightforward linear butene backbone with a phenyl ring at the tail. We do not pull those details out just because they read well in catalogs. In practical use, that combination influences reactivity and function. The terminal double bond means 4-Phenyl-1-Butene handles as an effective alkene partner for many addition reactions, giving it more value in synthesis routes for specialty polymers, flavors, and pharmaceuticals. Our team has supported customers developing new synthetic rubbers, agrochemical intermediates, and designer molecules where a stable, aromatic alkene keeps the project on track.

    We have seen customers come to us with a spectrum of requests, from precise stabilization requirements for storage, to the need for both glass and steel-compatible packaging. Because 4-Phenyl-1-Butene holds onto both alkene and aromatic reactivity, its shelf life comes down to quality handling and packaging more than for some more robust hydrocarbons. Each specification upgrade—from stabilizer addition to inert atmosphere packaging—draws directly from customer feedback and real-world degradation trials in our own lab.

    Model and Specifications from an Operator’s Perspective

    4-Phenyl-1-Butene flows through our production division in lots typically ranging from 20 kg lab-scale to metric ton lots for major projects. As chemists know, not all samples are equal. Over the years, we designed our plant streams for high-purity, low-moisture output. GC analysis regularly shows purity upwards of 99 percent, but full certification digs deeper: water content, color index, and trace impurities like residual toluene or styrene derivatives get tracked by our in-house quality team. Our reactors are calibrated for consistent conversion, cutting side product formation that complicates downstream processing.

    Thanks to that tight process, customers receive 4-Phenyl-1-Butene with a light, clear appearance and no sharp odor, which operators in flavor and fragrance lines have cited as critical. We follow up with monitoring how our drums and intermediate bulk containers perform across international shipments. Packaging gets reviewed with every major order—it does no good to ship high-purity product if it oxidizes before reaching a plant four weeks later. Direct feedback has pushed us to stock both standard steel drums and fluoropolymer-lined containers for extra sensitive customers.

    Applications Rooted in User Needs

    From our experience, 4-Phenyl-1-Butene gets the most interest in two areas: intermediate synthesis and polymer modification. In the pharmaceutical sector, chemists value the non-activated double bond paired with a phenyl group because it opens access to unique carbon backbones. We have seen production requests for custom cyclization reactions, Grignard additions, and even selective functionalization where steric hindrance helps guide regioselectivity. Some clients bring in their own catalyst systems, others probe for advice on handling scale-out. Either way, we have observed that the reliability of our material shapes their success rate.

    In polymer science, 4-Phenyl-1-Butene serves as a functional comonomer for introducing rigidity and aromatic content to new materials. Process engineers report that small additions (sometimes less than 5 percent by mol) change the glass transition temperature of polyolefins and can adjust sticking points in extrusion. Our technical division regularly supports bench scale applications, from compatibility tests in solution polymerization to batch trials with post-polymerization blending. We hear back about lot-to-lot uniformity and contamination risks; that data feeds into the future design of our in-process controls.

    We do not only focus on established markets. Emerging research in specialty surfactants, fine fragrance molecules, and advanced lubricants takes advantage of the structural features in 4-Phenyl-1-Butene. Perfume and aroma manufacturers look for the clean, phenyl-based motifs in this molecule, especially when synthetic restrictions prevent natural extraction. The tight control over trace byproducts—like removing any sulfur-based impurities—serves these industries particularly well.

    What Sets Our Process Apart

    Not all manufacturers use the same route or care for product finish. Some competitors offer 4-Phenyl-1-Butene reprocessed from crude distillates, introducing minor isomers or trace tars. We have witnessed how sensitive downstream chemistry can be. Our plant employs a dedicated synthesis pathway based on selective alkylation and high-vacuum distillation. Years of investment in corrosion-resistant reactors and analytical support show up not only in the main assay readings but also in diminished batch variability. That means fewer surprises in both lab discovery and full-scale production.

    By maintaining in-house tracing on every raw material and batch, our QC teams pick up trends in impurity drift or container contamination quickly. When we field questions about color shifts or unexpected side products, there is no wait for an overseas factory reply—we have the runs, logs, and analytical screens in our own archives going back years. Our technical team engages with researchers both before and after procurement, aiming for an ongoing problem-solving relationship, not just commodity transactions.

    Direct feedback from research and industrial partners pointed us toward continuous reactor upgrades and process tweaks. One project led to double-filtration to cut haze, another spurred us to offer ultrapure, inhibitor-free grades tailored for sensitive hydrogenation work. We do this not because it looks good in brochures, but because troubleshooting for actual customers led to that solution. Those changes stay in place after each successful run, lifting the baseline quality for the next round.

    Comparing 4-Phenyl-1-Butene to Related Products

    We often get questions on how 4-Phenyl-1-Butene stacks up against similar or adjacent molecules. Some researchers start with 1-Butene or alpha-olefins, figuring the substitution won’t make much difference. From practical experience on the bench and in large reactors, we have seen how the bulky phenyl group fundamentally shifts both reactivity and physical properties. For instance, while simple butenes may undergo polymerization or addition smoothly, the aromatic ring in 4-Phenyl-1-Butene introduces both pi-stacking and added electron density, which can slow or alter typical alkene reactions. For polymer scientists, this means the copolymer will often display noticeably higher rigidity and altered optical properties compared with non-aromatic analogs.

    Cinnamyl derivatives appear similar at first glance, but the position of the double bond relative to the aromatic ring makes a real difference. In our hands, 4-Phenyl-1-Butene stays much more stable under standard storage and shipping conditions than cinnamyl-based compounds, which often show polymerization or color shift unless strictly inhibited. In processes like metathesis or cross-coupling, the position of the alkene controls regioselectivity, which shapes yield and purity in later steps. These are not vague differences—they play out in real-world batch successes and troubleshooting sessions.

    Styrene stands apart as both a commodity and specialty aromatic monomer, but it polymerizes far more easily than 4-Phenyl-1-Butene and suffers from rapid oxidation and yellowing without inhibitors. Clients who come to us after working with styrene appreciate the much higher storage stability, lower reactivity toward air, and easier handling characteristics. There is less need for complex inhibitor management or environment controls across the warehousing and transit chain.

    Real-World Production Challenges and Solutions

    Manufacturing 4-Phenyl-1-Butene at scale does not only hinge on balancing a reaction equation. Plant engineers monitor temperature and pressure regimes that trade off between reaction yield and impurity formation. Our pipelines were designed to prevent static buildup and oxygen ingress—details that cut down on off-odors or peroxide formation in the final product. On the shop floor, we keep a close eye on pumping rates to avoid vacuum losses that would otherwise spike impurity profiles.

    One common concern raised by partners is cumulative low-level contamination from repeated drum reuse. In response, our facility implemented a replacement schedule for all storage containers that handle high-value grades. Labs visiting to audit our process have cited our container tagging and historical batch tracking as a key quality assurance point. These are not just technical details: failed batches and unpleasant surprises often come down to overlooked handling practices rather than the chemical formula itself.

    Packaging choices arise from practical experience. We regularly ship to locations ranging from humid port cities to dry inland hubs. Each shipment must stand up to variable climate and transit times. Our team cycles through packaging formats, gaskets, and liners to prevent leaks or internal buildup, discussing container performance with logistic and receiving staff after every major delivery. Even small feedback such as a slightly sticky drum or change in odor can clue us in to process adjustments.

    Sustainability and Regulatory Focus

    The push for greener chemical synthesis impacts everything from our reagent selection to our off-gas treatment. 4-Phenyl-1-Butene sits at an intersection between fossil-derived feedstocks and tailored molecular architecture. Plant operators and process engineers have worked to cut input waste and capture solvent emissions during every run. Our internal initiative led to solvent recovery systems and high-efficiency chillers that trim both input costs and environmental impact. It is clear from regulatory updates that trace volatile organics and waste tracking will keep tightening, especially for aromatic production chains. We have moved ahead with emission controls even before mandates, learning from previous infractions that drove corrective investments upstream.

    On the registration front, our compliance team checks that every outgoing batch meets not only internal testing but also registration numbers and region-specific compositional guidelines for import or local use. We build documentation packages from raw data at the reactor, not reverse-engineered after the fact for paperwork. This heads off many costly rejections or slowdowns at customs, which frustrate both buyers and manufacturers alike.

    Advice and Learning from Industry

    Years of producing and refining 4-Phenyl-1-Butene have taught our staff that even small formulation differences can lead to outsized effects for formulators and end users. We invest in knowledge transfer, sharing impurity profiles and detailed process documentation with development partners so changes in synthesis don’t backfire downstream. More than once, a technical exchange on alkene handling has prevented costly reformulation or saved a client a lost production run.

    Any researcher or production lead considering 4-Phenyl-1-Butene should weigh the importance of system compatibility, especially if trying to swap it against similar chemicals like cinnamyl analogs or basic butenes. Our technical service group maintains case notes on successful and failed switches across a range of applications, with clear detail on purification, blending, and shipment performance. This experience turns into up-front project advice, not merely a quality spec on a one-page flyer.

    End users in pharmaceutical, polymer, and specialty chemical research sometimes request custom lots with tight impurity and packaging standards. From in-house runs, our team can recommend realistic windows for batch variability based on actual plant performance, avoiding overpromising on specs that can’t be met at scale. Input on these topics has prompted upgrades and process redesigns that continue cycling back to better performance and greater reliability with every new order.

    Growth and Future Opportunities

    We keep a close watch on new application fields that draw from the unique features of 4-Phenyl-1-Butene. A recent uptick in demand came from advanced polymer blends and green chemistry projects aiming to replace legacy aromatic inputs with more stable and tunable molecules. Early-stage researchers often reach for traditional hydrocarbons, but collaborative efforts have proven that reactivity and long-term stability matter as much as base price and supply rate. By remaining open to feedback—both good and constructive—we have been able to support growing fields that value both chemical design and practical delivery.

    Our lab and pilot plant have begun extending work on enantioselective functionalization and catalysis using 4-Phenyl-1-Butene as a versatile starting point. Chemists and process engineers work together to ensure that we can translate successful bench chemistry to the drum and truckload scale, maintaining consistency alongside innovation. Some of the most promising new uses involve engineered materials and fine chemical derivatization, where risks of byproduct formation are especially critical.

    Looking at shifting market requirements, from global flavors to precision pharmaceutical synthesis, the simple decision to invest in better analytical support and operational traceability often unlocks greater confidence for all partners in the supply chain.

    Rooted in Experience, Committed to Progress

    As the chemical industry shifts toward higher complexity and accountability, the difference between a commodity source and direct manufacturer becomes clearer. Experience has shown us that plant floor know-how, tight process feedback, and genuine customer dialogue make all the difference. 4-Phenyl-1-Butene may sound niche, but the lessons learned from years of hands-on production, troubleshooting, and continuous improvement pay dividends for every new batch, industry partnership, and emerging use case developed together.