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4-Nitroso-N,N-Diethylaniline

    • Product Name 4-Nitroso-N,N-Diethylaniline
    • Alias N,N-Diethyl-4-nitrosoaniline
    • Einecs 211-248-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    262116

    Chemical Name 4-Nitroso-N,N-Diethylaniline
    Cas Number 1126-19-6
    Molecular Formula C10H14N2O
    Molecular Weight 178.23 g/mol
    Appearance Green to dark green crystals or powder
    Melting Point 85-88°C
    Boiling Point 324°C
    Solubility Slightly soluble in water; soluble in alcohol and ether
    Density 1.11 g/cm3
    Synonyms N,N-Diethyl-4-nitrosoaniline
    Pubchem Cid 13493
    Inchi Key LZELERKGTDGJEP-UHFFFAOYSA-N

    As an accredited 4-Nitroso-N,N-Diethylaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Brown glass bottle, 25 grams, tightly sealed with a screw cap, features hazard labeling, product name, and supplier information prominently displayed.
    Shipping 4-Nitroso-N,N-Diethylaniline should be shipped in tightly sealed containers, away from light, heat, and incompatible substances. It must be labeled as a hazardous chemical and handled with appropriate safety precautions. Typically, it is shipped via ground transport under regulations for toxic, organic compounds, ensuring protection against leaks, spills, and environmental contamination.
    Storage 4-Nitroso-N,N-Diethylaniline should be stored in a tightly sealed container, kept in a cool, dry, and well-ventilated area away from light and incompatible materials like strong oxidizers and acids. It should be protected from moisture and sources of ignition, and access should be restricted to trained personnel. Proper labeling and compliance with local chemical storage regulations are essential.
    Application of 4-Nitroso-N,N-Diethylaniline

    Applications of 4-Nitroso-N,N-Diethylaniline in Industrial Manufacturing

    As a direct manufacturing supplier, we support global chemical companies with 4-Nitroso-N,N-Diethylaniline, a key intermediate for specialty synthesis across multiple industrial downstream markets. Below, we detail real, compliance-driven sectors utilizing our material and the exact integration points supporting process efficiency and product quality.

    1. Dye Intermediates for Organic Pigment Synthesis

    Pigment manufacturers use this compound as a coupling component during the production of azo and anthraquinone dyes. The material enables controlled nitroso reactions to form color bodies with high tinctorial strength and stability, mainly for plastics, coatings, and textile coloration. Handling requires calibrated dosing to maintain consistent color shades, minimal impurities, and robust lightfastness, particularly when scaling batch production lines.

    Industry compliance standards

    • OEKO-TEX STANDARD 100 – Restricted Substances for Textile Dyeing
    • REACH Regulation (EC) No 1907/2006 – Substances Registration and Use
    • ISO 9001:2015 Quality Management for Specialty Chemicals
    • ISO 1833-11:2019 – Analysis of Textile Colorants

    Typical usage ratio

    • 0.5%–2.5% w/w relative to diazo component; adjust based on target shade intensity and substrate reactivity

    Downstream process integration

    • Charged to nitrosation vessel after formation of diazotized aromatic amine, reacts under controlled pH and temperature to yield pigment precursor

    Final product types

    • Azo pigments for plastics
    • Anthraquinone dyes for industrial coatings
    • Sulfonated dispersions for textile dyeing
    • Masterbatch colorants for fibers

    2. Analytical Reagents and Colorimetric Sensors Manufacturing

    Specialty chemical and laboratory supply companies employ this raw material in the synthesis of colorimetric reagents, especially for trace metal ion analysis. It forms deeply colored complexes with transition metals, enabling sensitive visual and instrumental detection in industrial water treatment, clinical diagnostics, and environmental QA labs. Controlled purity minimizes background interference in analytical protocols.

    Industry compliance standards

    • ISO/IEC 17025:2017 Laboratory Accreditation
    • EPA Method 200.7 for Water Analysis
    • USP General Chapter <231> for Heavy Metals (if used in pharma analysis)
    • RoHS 2 Directive 2011/65/EU (for electronics grade reagents)

    Typical usage ratio

    • 10–40 mg/L in working solution, adjusted for detection limit and matrix composition

    Downstream process integration

    • Added to reagent formulation tank during batch preparation, then blended with buffer and auxiliary complexing agents

    Final product types

    • Pre-packed analytical test kits for spectrophotometry
    • Strip-based colorimetric sensor cards
    • Lab-grade metal ion detecting solutions
    • Ready-to-use water quality screening reagents

    3. Pharmaceutical Intermediate for API Synthesis

    Pharmaceutical manufacturers require this molecule as a building block for certain active ingredient syntheses. It participates in specific nitroso coupling or reduction steps, contributing to molecular frameworks with pharmacologically relevant functionalities. Guarantees on trace impurity levels and complete batch traceability are central for regulatory submissions and downstream compliance.

    Industry compliance standards

    • Good Manufacturing Practice (GMP), ICH Q7 and EU GMP Parts I, II
    • 21 CFR Part 211 – FDA cGMP for Finished Pharmaceuticals
    • EDQM CEP for excipient/intermediate registration
    • USP, Ph. Eur. where relevant

    Typical usage ratio

    • 1.2–3 molar equivalents relative to amine or reactant; determined by process yield optimization and impurity limits

    Downstream process integration

    • Dosed into the intermediate synthesis stage by automated metering system, often followed by subsequent reduction/hydrolysis steps

    Final product types

    • Intermediate compounds for antihistamine APIs
    • Pharmaceutical fine chemical building blocks
    • Key advanced intermediates for custom drug synthesis
    • Process-controlled bulk drug substances (for later reaction steps)

    4. Rubber Chemicals and Vulcanization Accelerator Production

    Producers of rubber additives incorporate this specialty nitroso compound during synthesis of accelerators used for vulcanizing natural and synthetic elastomers. The compound acts as a precursor within multi-step chained reactions, influencing cure time, crosslink structure, and final mechanical properties. Consistent lot purity ensures reliable process reproducibility in continuous and batch rubber compounding.

    Industry compliance standards

    • ASTM D4678 – Practice for Rubber Chemicals in Compounding
    • ISO 9001:2015 for Production Traceability
    • REACH Regulation (EC) No 1907/2006 – Registered Substances
    • China GB/T 21867-2008 for Rubber Additives

    Typical usage ratio

    • 0.1–0.5 phr (parts per hundred rubber) as a reaction intermediate, calculated by downstream accelerator synthesis route

    Downstream process integration

    • Fed to pre-reactor for nitrosation step, then post-processed to yield sulfenamide or thiazole accelerator compounds

    Final product types

    • MBTS and CBS class vulcanization accelerators
    • Blended rubber additive masterbatches
    • Industrial tires and automotive hoses components
    • Technical rubber goods (seals, belts, conveyor compounds)

    5. Photographic Chemical Formulations

    Photographic chemical suppliers use this material during the manufacture of developers and stabilizers for analog film processing. Its precise interaction with silver halides aids controlled image formation, anti-haze functions, and speed regulation in black-and-white and color applications. Reliable color formation and minimal process-induced fog are achieved through careful raw material screening and batch QC.

    Industry compliance standards

    • ISO 9001 for Production Batch Control
    • ANSI/NAPM IT9.2-1991 – Imaging Material Stability
    • REACH and TSCA Inventory Listing
    • Japan JIS K0120:2013 for Photographic Chemicals

    Typical usage ratio

    • 0.05–0.3% w/w in developer concentrate, based on required development speed and anti-fogging performance

    Downstream process integration

    • Added to developer blending tank after dilution of main developing agents, followed by filtration and packaging for end-users

    Final product types

    • Photographic film developing solutions
    • Stabilizers for silver halide emulsions
    • Commercial image processing kits
    • Archival treatment chemicals (analog photo storage)
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    Certification & Compliance
    More Introduction

    Exploring the Distinctions of 4-Nitroso-N,N-Diethylaniline: Experience from the Production Floor

    Understanding 4-Nitroso-N,N-Diethylaniline from a Manufacturer’s Perspective

    As a chemical producer who works closely with 4-Nitroso-N,N-Diethylaniline each week, I appreciate how this compound shapes both lab work and industrial processes. Anyone who has stood over a reactor vessel, watching the subtle color change as the nitroso group forms, starts to see the real nature of this specialty chemical. Its production may seem straightforward to an outsider: starting from N,N-diethylaniline, controlling temperature, humidity, and feed rates, and monitoring purity levels — but every batch brings its own small set of challenges. A mistake in raw material quality or timing won’t just alter yield, it can create impurities that are hard to spot and harder to remove.

    Our facilities keep a close eye on specs because consistency matters more than any certificate or brochure suggests. 4-Nitroso-N,N-Diethylaniline requires tight analytical standards, particularly for industries that demand extended traceability and analytical data. Purity is no marketing term; it means a difference between a clear result and a batch headed for rework. For most of our long-term buyers, value isn’t found in a product’s technical sheet but in a transparent production record, batch after batch, year over year.

    The Tangible Qualities: Model and Specifications That Truly Count

    We manufacture 4-Nitroso-N,N-Diethylaniline primarily in powder form, maintaining strict moisture and particle size control. Each batch receives a unique identifier, and we track analytical values for nitroso content, total moisture, and related impurities with validated in-process testing routines. Our internal model divides product grades by intended end use. For example, material destined for spectrophotometric analysis often carries a tighter threshold for trace contaminants compared to grades used in dye intermediate production.

    Some customers look for bulk supply with a clean nitroso signal on their HPLC scans, while smaller orders may request double-staged filtration. Every requirement comes with its own impact on cycle time and logistics. Honestly, the paperwork and record-keeping for these grades often consume as much effort as synthesis itself. Over years in this facility, side-by-side specification reviews have become second nature. We never draw lines between technical and analytical grades based simply on what’s written in an industry manual — experience taught us that the subtleties in raw material selection or water quality in a particular batch can define the product just as much as formal purity numbers.

    Differences That Affect Daily Operations

    Among related aromatic nitroso compounds, subtle distinctions in molecule structure change everything: application, handling, and storage all shift based on factors beyond a single functional group. 4-Nitroso-N,N-Diethylaniline wears its own identity in the lab and in the warehouse. By comparison, mono-alkylaniline nitroso derivatives show different solubility profiles and volatility. Even in storage, our team keeps 4-Nitroso-N,N-Diethylaniline drums away from heat and direct sunlight, as even slight temperature excesses promote slow degradation. The powder itself clumps or compacts easily if humidity climbs too high for too long, which requires vigilant warehouse tracking.

    Another related point: while many nitroso-aromatic intermediates drive colorant work, only the diethylaniline derivative gives certain color properties essential for the manufacture of azo dyes and pigment precursors. That sharp separation, which may look like a subtlety to an end user, runs deep for those measuring shade, intensity, and batch repeatability. If you blend the wrong grade or substitute a similar compound, entire downstream lots of pigment or indicator solution may turn out unacceptably — we’ve seen production holds from just a trace contaminant in a supposedly equivalent grade from outside vendors.

    This Compound in Practice: Value Beyond the Lab Bench

    From my perspective on the shop floor, 4-Nitroso-N,N-Diethylaniline mostly exits our plant for use as a diagnostic reagent and in dye manufacture. Academic and clinical research groups often use it for diazotization studies, while pigment houses require stable lots for chromatic consistency. Our own end-use experience taught us not to downplay details during order planning. Every packaging decision — double-sealing, inert gas purging, or robust batch documentation — takes cues from either a client’s previous issues or our team’s own findings.

    Clients in applied chemistry often mention the compound for its use in photometric detection methods. The interaction of this molecule with various oxidizers or reducing agents gives quantifiable, reliable results in the right matrix. If a batch comes out with small impurity spikes or visible microclumps, assay accuracy falls off. We’ve fielded troubleshooting requests from labs seeing out-of-spec results, only to track findings back to unnoticed microvariations in our own grind size or container material. That kind of feedback loop earns its place on our shop floor; every time we improve a procedure, we see fewer problems down the line.

    The bulk market for 4-Nitroso-N,N-Diethylaniline in dye chemistry proves equally sensitive. The final color strength of many pigments depends not just on core chemical content, but on how the precursor behaves during blending, heating, and formulation. A drop in stability or a subtle shift in the solubility curve can require reformulation work for downstream partners. Color houses will sit with us for hours reviewing pilot lots and side-by-side mixing tests. They rightfully demand a product that moves continuously, without batch-to-batch drift, and a supplier who understands the feedback they bring from their own quality labs.

    Challenges in Reliable Supply and Process Variability

    Production teams confront regular hurdles, not all of which show up in textbooks or standard operating procedures. Over my years on this line, I have tracked more delays due to raw material sourcing changes than plant mechanical faults. Small changes in aniline derivative supply or shifts in transportation timelines can break an otherwise seamless production week. Careful follow-up with every upstream partner is crucial. Misjudged shipping windows or a missed impurity peak in a supplier’s lot can bring headaches back to our own operation, turning simple synthesis into a balancing act.

    Our solution has always involved direct sourcing relationships and a readiness to validate every incoming drum with our own in-house tests, even when a paper certificate claims full compliance. Running comparative blends and back-to-back batches lets us see small differences before they expand into bigger problems, especially as repeat clients rely on us to flag variation. We neither chase rock-bottom input pricing nor turn a blind eye to batch-to-batch variation in raw stock.

    Operator training ranks right at the top of our priorities each quarter. A skilled production team picks up on subtle clues: unexpected color before filtration, odd residue on the reactor wall, a change in the way material handles on discharge. No batch management system can replace a team used to spotting these outliers or making quick adjustments. This day-to-day vigilance keeps product recalls less likely, and gives us early warning long before an issue reaches our logistics department or end user’s bench.

    Keeping Purity and Traceability Center Stage

    Most 4-Nitroso-N,N-Diethylaniline users ask tough questions about batch traceability. Experience at the manufacturing level has taught us to expect such audits — not just from regulatory auditors, but from every sharp formulator and procurement specialist who has been burned by inconsistency elsewhere in the supply chain. Though analytical reports travel with every shipment, our own plant logs cover more than simple titrations. We hold onto trend charts of temperatures, pH settings, and batch weights, marking all deviations or operator-led interventions.

    While these records demand painstaking attention, the payoff arrives with trust. Over time, the accumulation of data from upstream and downstream lets us spot seasonal trends in raw materials, or see long-term shifts that might threaten specification compliance. The value in those archives grows with each new audit request or formulation review. Consistency arises not from lucky batches, but from hundreds of controlled adjustments and careful retraining every year.

    This attention to record-keeping and background data extends to our approach with clients. During specification meetings, we routinely review both hits and misses with buying teams—an approach that builds loyalty rather than simple transaction-based supply. Any blip in assay results, even if within reported tolerance, prompts us to pull back and look at procedural drift or supplier issues. Rejection rates, while low compared to industry average, drop further as we tackle root causes openly alongside our partners.

    Strategies for Improving Value and Performance

    While production formulas for 4-Nitroso-N,N-Diethylaniline often date back decades, steady improvement and learning never stop. We don’t just memorize decades-old directions; every process control improvement grows out of a history of both avoidable and unpreventable mistakes. Cooling time adjustments reduce byproduct formation, tighter particle size screening stops dusting at the filling station, and better storage guidelines cut down on caking or slow oxidation.

    Maximum value, both for us and our customers, comes from dialogue with those who put this compound to actual use. Long-term buyers never hesitate to give us feedback about handling results, spectral clarity, or packaging flaws. Formal complaints rarely provide as much improvement as daily informal notes and phone calls from the lab team at a pigment company or a chemistry professor attempting to use a new chemical standard.

    We have also learned that batch segmentation — effectively, running parallel lots for particularly sensitive downstream blends — prevents cross-contamination and supports traceability for users working under regulatory supervision. Splitting production and packaging by end use category keeps us one step ahead when responding to new regulatory requests, unforeseen supply issues, or an end user’s sudden shift in specification.

    In practical terms, every tweak to the workflow and analytical routine happens because someone further down the supply chain communicates openly. A nod from a project leader at a dye synthesis plant, flagging a slight drift in their output, can trigger valuable changes in our process. We make every procedural change with an eye not on the short-term metric but on long-term partnership.

    Why 4-Nitroso-N,N-Diethylaniline Remains Essential for Industry Professionals

    The specific features of 4-Nitroso-N,N-Diethylaniline make it more than a commodity for most professionals in dyes and analytical chemistry. The stable nitroso group, predictable reaction profile, and defined impurity range help build confidence in process and final product. Unlike similar nitrosoanilines, which often show erratic responses in photometric applications, the diethylaniline derivative’s structure provides reliable color development, critical for calibrating complex laboratory equipment and producing consistent pigment batches.

    We regularly hear from engineers and chemists who rely on sharp batch definition. They don’t just buy quantity; they demand performance. A minor impurity or drift in spectral response means costly retesting and reworking in their own plants. That’s a consequence that hits home for us as much as for them. We respond by tuning our process in real time, maintaining continuous dialogue with our clients so their needs inform our next round of improvements.

    Mid-size pigment manufacturers and research teams regularly join us for technical reviews, discussing product performance at a granular level. Their reports highlight which process variables require more control, which raw material sources merit reconsideration, and where our technical data may help answer regulatory queries. This collaborative review process strengthens trust and keeps our output keenly matched to changing industry targets.

    Commitment to Long-Term Improvement and Partnership

    No production line or plant team can promise perfection. What we offer is transparency, accumulated experience, and a direct connection to those who choose us for their 4-Nitroso-N,N-Diethylaniline needs. In the rare event a client finds a quality concern, our whole operation treats the finding as actionable knowledge. By working openly with external auditors, regulatory agencies, and downstream technical staff, each issue, large or small, strengthens our process moving forward.

    Long-term process improvement means far more than keeping pace with competitors or chasing certifications. We see it in sharper crystal clarity, less shipment spoilage, faster batch transitions, and lower rates of on-site troubleshooting. Our partners, with their own industries to serve, rely on us to keep up not only with published specification sheets, but with practical demands that emerge around the corner — a new photometric method, a tighter dye shade parameter, or greener packaging requirements.

    We invest in our team, our plant, and our data infrastructure. This isn’t just about staying current; it builds resilience for all partners in the chain. As industry moves further toward digitalization and greater transparency, our plant’s readiness only grows. I’ve watched new generations of chemists join our staff and client base, bringing sharper questions and fresh demands. We take those demands as prompts for education and continued evolution.

    The Direct Manufacturer’s Approach: More Than a Product, a Partnership

    4-Nitroso-N,N-Diethylaniline, from our vantage point on the production side, represents both challenge and opportunity. We embrace the detailed requirements of our partners in pigment and analytical chemistry, translating each feedback point into concrete improvements. Far from a generic raw material, its production and supply demand hands-on attention, smart sourcing, and continuous mutual engagement with every end user — a process as open-ended as applied chemistry itself.

    Anyone searching for shallow "me-too" chemistry or box-pushing distribution channels will find our approach refreshingly different. Every order, whether for a few hundred grams or a truckload, carries the backing of decades in the field and a belief in long-term, fact-based solutions. While the chemistry behind 4-Nitroso-N,N-Diethylaniline runs deep, what matters most is the ongoing connection between those who produce it and those who rely on precise, reliable results every day. For us, that relationship defines real value — not just for today’s marketplace, but for years of shared growth and continuous improvement ahead.