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HS Code |
832499 |
| Name | 4-Hydroxy-4-Methyl-2-Pentanone |
| Synonyms | Diacetone alcohol |
| Cas Number | 123-42-2 |
| Molecular Formula | C6H12O2 |
| Molar Mass | 116.16 g/mol |
| Appearance | Colorless liquid |
| Boiling Point | 166-167 °C |
| Melting Point | -47 °C |
| Density | 0.938 g/cm³ at 20 °C |
| Solubility In Water | Miscible |
| Flash Point | 58 °C (closed cup) |
| Refractive Index | 1.423 (20 °C) |
| Odor | Mild, menthol-like |
| Vapor Pressure | 0.49 kPa at 20 °C |
| Pubchem Cid | 31254 |
As an accredited 4-Hydroxy-4-Methyl-2-Pentanone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250 mL amber glass bottle with a tamper-evident cap, labeled “4-Hydroxy-4-Methyl-2-Pentanone, CAS 123-42-2, analytical grade.” |
| Shipping | 4-Hydroxy-4-methyl-2-pentanone (also known as diacetone alcohol) should be shipped in tightly sealed containers, protected from sunlight, ignition sources, and moisture. It is classified as a flammable liquid and may require labeling under relevant transport regulations. Appropriate safety documentation and compliance with local, national, and international shipping laws are necessary. |
| Storage | 4-Hydroxy-4-methyl-2-pentanone should be stored in a cool, dry, well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizers and acids. Keep the container tightly closed when not in use. Store in a chemical-compatible container, clearly labeled, and protect from direct sunlight and moisture to prevent degradation and maintain chemical stability. |
Applications of 4-Hydroxy-4-Methyl-2-Pentanone in Industrial ManufacturingAs a direct manufacturer of 4-Hydroxy-4-Methyl-2-Pentanone (also known as Diacetone Alcohol, DAA), we focus our supply chain integration on proven, high-volume downstream applications. This material serves as a critical intermediate and solvent across several specialized sectors. The following sections detail real industrial deployment, covering compliance regimen, formulation use level, production process interface, and resulting downstream products. 1. Industrial Coatings and Paint FormulationManufacturers formulate industrial coatings and paints with DAA to achieve controlled evaporation rates and enhanced flow characteristics, especially in water-based systems where solubility in both water and organic solvents is required. Its high-purity grade reduces blush in automotive and general industrial topcoats, aligning with regulated VOC content. DAA typically enters the production process during the resin dissolution stage, acting as a co-solvent and viscosity regulator for acrylic, nitrocellulose, or polyurethane-based systems. End users rely on stringent batch control for compatibility with pigment dispersions, targeting performance on steel, aluminum, and engineered plastics. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
2. Solvent for Adhesives and SealantsAdhesive and sealant manufacturers use DAA to balance solubility and open time in complex polymer systems, such as polyurethane, acrylic, and vinyl emulsions. Its controlled evaporation rate supports smooth application and minimization of air bubbles during film formation. DAA is typically incorporated during the intermediate or final solvent charging step in industrial mixers to optimize rheology and facilitate uniform dispersion of reactive resins, plasticizers, and functional fillers. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Chemical Intermediate for Solvent SynthesisDAA functions as a primary feedstock in industrial synthesis routes for methyl isobutyl ketone (MIBK) and methyl isobutylcarbinol (MIBC), both important solvents in paints, extracting industries, and rubber. Chemical producers hydrogenate or dehydrate DAA in catalytic reactors under controlled pressure and temperature, requiring consistent purity for high conversion rate and minimal by-product formation. Integration with in-line analytical control ensures compliance with downstream product quality for export and domestic use. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Solvent for Printing InksThe printing ink industry adopts DAA as an active component of solvent blends to fine-tune drying rates, maintain pigment dispersion stability, and boost gloss, particularly in flexographic and gravure processes. Its application targets high-speed web printing, where rapid solvency is essential for sharp image transfer on flexible packaging films, foils, and labels. Quality control teams monitor residual solvent content to comply with migration limits, incorporating DAA during pre-mix and letdown stages. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
5. Cleaning Agent in Electronics and Precision EquipmentCleaning systems in electronics manufacture utilize DAA for removing flux residues, particulates, and processing oils due to its high solvency and relative compatibility with sensitive plastic and metal surfaces. ESD-controlled environments require residue-free performance and full conformity to restricted substance protocols. Operators introduce this solvent during ultrasonic bath or wipe-clean procedures, monitoring for quick evaporation and non-aggressive material compatibility in component cleaning and final assembly. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
6. Intermediate for Pharmaceutical SynthesisThe pharmaceutical sector relies on DAA as a building block in the synthesis of active pharmaceutical ingredients via aldol condensation or protective group strategies. Its control-grade quality supports high-yield reactions and meets strict impurity and residual solvent thresholds in GMP manufacturing. Chemists feed DAA into reaction vessels during the intermediate step of multi-stage processes, ensuring in-process verification and compliance with monograph limits for finished API. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
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Many years on the chemical production floor have taught us that customers don’t just want a label or a batch number. They’re looking for reliability batch after batch, and with 4-Hydroxy-4-Methyl-2-Pentanone, often abbreviated as diacetone alcohol, we’ve seen what it means to deliver a product that holds its value across industries. The process doesn’t start in a boardroom or with a brochure. It starts at the reactor, where quality controls drive every stage – from raw material selection to purification. We build our processes around consistency because a single impurity shifts paint formulations, coatings, or adhesives far from specification.
As a direct producer, we don’t approach 4-Hydroxy-4-Methyl-2-Pentanone as a broad commodity to blend into anonymous lots. We ask what matters. Precision in purity stands at the front. We track levels of water, acidity, and aldehydes, and we’ve learned from customers who run high-precision synthesizing operations that even minor byproducts can interfere with reactivity or shelf stability. Usually, our material reaches above 99.0% purity, and we see requests for this grade from coatings and pharmaceutical intermediates.
This liquid brings a mild, pleasant odor, with solvent properties that have yet to be fully matched by other mid-length ketones. We’ve put in hours testing its performance in resins and coatings, where its high boiling point of around 166°C stands out. Not all solvents evaporate at the right pace for lacquer or ink applications, but here we see a smooth, controlled drying time that manufacturers value. That lets formulators avoid issues like “blush” or uneven coatings. Compared with lower-boiling ketones like methyl ethyl ketone (MEK) or acetone, diacetone alcohol lingers, allowing more working time, which matters in spray and dip applications, especially when humidity swings with the season.
We’ve heard it said that chemical identity is only half the story. The other half lies in the trust built with users who have come to us after inconsistent results with traders or middlemen. By controlling the entire manufacturing loop, and not just filling barrels, we carry out lot-by-lot analysis for peroxides, moisture, and residual starting materials.
Dealing with our own process means we hold our ground against common pitfalls: contamination from bio-feedstocks, trace metals, even minor esters that find their way in if cleaning steps come up short. A purification bottleneck early on taught us the hard lesson that customers don’t just buy a percentage; they buy a performance promise. Miss that, and coatings turn cloudy or shelf stability drops. We’d rather lose a sale than ship something unfit for end-use.
Painters, ink makers, and adhesive formulators rely on more than a boiling point for selection. They look for miscibility with both water and oil – a trait not common with many solvent classes. We watch our product work to its strengths when blended with water-based acrylics. It tames the blend, reducing tackiness while helping pigments spread evenly. A pure grade leaves fewer yellowing residues over time, making it a go-to solvent for finishes that will stretch across years of exposure.
Customers in synthetic resin production explain that the low rate of side reactions keeps curing times consistent. We’ve reviewed hundreds of feedback notes highlighting its clear advantage over straight acetone, which flashes off too fast and can drag defects into the final product. Technicians working with UV-curable lacquers confirm the same – nothing beats the slow, even evaporation in terms of surface finish.
The market is full of cheaper, lower-specification solvents. Methyl isobutyl ketone (MIBK) and methyl ethyl ketone (MEK) sometimes serve as substitutes, but they don’t bring the balanced volatility that users ask from diacetone alcohol. MIBK evaporates rapidly; it helps with fast drying but leaves little working window and often boosts solvent odors in ambient environments. MEK brings a lower boiling point and a fast-acting solvent punch, but that’s a double-edged sword in varnishes and lacquers, where controlling open time matters.
We’ve sat with R&D leads who tried to reformulate with those options, only to hit unforeseen hurdles: pigment flotation, orange peel surfaces, or excessive cost from added retarders. Switching back to diacetone alcohol, those problems faded. Its unique structure – a ketone with a secondary alcohol – strikes a blend of solvency and reduced aggressiveness that sits well with sensitive resins and finishes.
Regulatory and consumer pressure dishes out new mandates each year about volatile organic compounds (VOC) and workplace safety. Years ago, users shrugged at two-digit VOC scores. Now, every gram matters, and we see chemists hunt for options that slide under stricter regional thresholds. Here, our 4-Hydroxy-4-Methyl-2-Pentanone earns its keep: it brings moderate vapor pressure, with a relatively low odor profile, making it easier to formulate low-emission coatings and inks.
Some try glycols or even newer bio-based solvents, but feedback often points them back to diacetone alcohol for its blend of solvency, price point, and regulatory compliance. Our technical team tracks international standards, watching for updates from EPA, REACH, or emerging markets. We regularly update our documentation and support users who need to meet unique export or compliance demands. Unlike some new alternatives, diacetone alcohol has already cleared decades of regulatory hurdles. That provides real-world assurance, not just theoretical compliance.
We get the most detailed reviews from customers in automotive and high-performance OEM coatings. These users put our batches to the test in roller application, dip tanks, electrostatic spraying, and even automated flow lines. Water miscibility delivers a big advantage for hybrid resin systems. High solubility for resins lets them formulate stable, non-separating dispersions without endless trial and error.
We’ve worked with thermal paper and inkjet ink manufacturers who require minimal residue and consistent evaporation. They measure drying time, print resolution edge, and the chemical’s compatibility with reactive dye stocks. Even trace acidity from a poor separation will bleed color performance or wreck head nozzles in printer systems. In this field, there’s no hiding from a missed spec; feedback arrives fast, and so does reputational risk.
Our team stays hands-on, whether it means running pilot batches, dialing in column temperatures, or benchmarking our output against both American and Asian competitors. Problems surface in two places: inside inspection labs and on end-user lines. We set up double-screening on key impurities after a string of customer complaints about competitors’ product turning resin batches hazy. Out-of-spec product never leaves our storage tanks. That kind of zero-tolerance culture developed from decades of lost sleep tracking down the source of a flawed batch.
Chemists on our floor use their own senses – not just instruments – to catch off-spec tanks. A sharp odor or a cloudy appearance means a process needs attention. Human eyes and noses work alongside analytical gear, and that stops bad lots before they leave our hands. Years of experience hammered home that nothing escapes experienced operators’ notice. We keep investing in training and upgrades for safety and process control rather than just scaling up output at any cost.
From production tanks to customer warehouses, diacetone alcohol’s journey brings its own logistics challenges. It’s not always about getting drums from point A to point B. We monitor temperature, prevent exposure to humid air, and avoid prolonged journeys that risk quality shifts. Drums sealed tight at our plant reach customers with the same physical properties we certify. Any drift opens doors for dispute, so traceability and batch integrity anchor every shipment. Tracking every lot number, storage time, and point of transfer helps us investigate and resolve any anomalies customers report.
For export customers, particularly those facing long ocean routes, we safeguard against moisture ingress, which diacetone alcohol absorbs readily. In one instance, an overseas shipment faced customs delay and high heat, so we flagged additional retention samples and checked product upon arrival. Frequent stories from importers center on swings in water content or off-odors, but customers who work directly with us rarely face such incidents.
Continuous improvement isn’t just jargon—customers push us there, often with pain points no off-the-shelf product solves. We’ve developed custom purification steps for users making pharmaceutical intermediates, removing not just bulk impurities but also low-ppb traces that disrupt high-sensitivity syntheses. This commitment stems from direct feedback loops, where the same engineer troubleshooting a reactor is speaking daily with the customer team. Our onsite lab does more than routine QC; it handles process-scale samples, cross-checks customer returns, and benchmarks global brand standards.
Incoming raw material quality continues to grow in importance as new sources enter the supply chain. Synthetic acetone remains the backbone, but regional variations in process technology can affect the downstream profile. Over the years, we broadened our own sourcing base, buffering against market swings and keeping the process stable while others scrambled.
Years ago, “environmental compliance” sounded like a bureaucratic box to tick. Today, between community expectations and real regulatory weight, those efforts permeate every decision. We run closed-loop solvent recovery, drawing down waste loads and minimizing unintentional emissions well below common industry benchmarks. Onsite scrubbers, waste minimization, and energy tracking built themselves into our routine decisions more than any external mandate ever could.
Teams conduct monthly audits, not waiting for annually scheduled compliance checks. Operators buy in because accidents and local community backlash directly impact their daily lives, not distant managers. Over time, this ethos spreads to our partners and customers, who depend on a transparent, well-verified source. The knock-on benefits go well beyond regulatory reports; they build the reputation on which customer loyalty rests.
Our success depends on partnership more than just large-scale production. We bring our practical understanding to formulation teams that often struggle with transitions—such as emissions reductions, performance improvements, or switching base resins. Every challenge on our shop floor finds an echo in customer problems. We share field notes, solvent compatibility charts, and even custom performance data to help customers get the result right the first time.
Once, a client in a new digital ink system asked for rapid troubleshooting after a competitor’s solvent failed under heat. Close cycle analysis traced the errors to residual aldehydes, which we could control down to clean-room specs. A follow-up collaboration adjusted both our process and their application parameters, saving them a costly recall. These relationships build a shared resource pool, keeping innovation a continual, hands-on process rather than a one-off transaction.
Raw material shocks, supply chain meltdowns, and shifting regulatory costs hit all producers. Yet our focus stays on protecting product integrity. Some market players stretch inventory with lower-cost imports, diluting consistency. Years of experience taught us that cutting process corners quickly unravels a brand’s reputation. We invest in consistency and technical support, rather than discounts, knowing that repeated success earns business more reliably than flash sales.
Our customers see transparency not as a box to tick but as a long-term value driver. Direct communication about supply swings or lead time delays—even if the answer isn’t perfect—makes the real costs and limitations clear. Production plans on the user side benefit from accuracy more than wishful promises.
We’ve learned over decades that chemical manufacturing rewards steady hands and clear-eyed commitment. 4-Hydroxy-4-Methyl-2-Pentanone continues to hold a valued spot in countless formulations not because of theoretical advantages, but thanks to performance proven by real-world users.
We place trust in transparent processes, tight quality controls, and technical collaboration. These create products that deliver practical results and navigate industry changes season after season. If better results matter, direct knowledge and accountability from the actual manufacturer always come out ahead of repackaging or trading layers. Our entire production—from sourcing and analysis to customer support—reflects this principle with every kilogram shipped.