Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

4-Amino-N,N-Dimethylaniline Oxalate

    • Product Name 4-Amino-N,N-Dimethylaniline Oxalate
    • Alias 4-ADMA Oxalate
    • Einecs 223-677-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    337729

    chemical_name 4-Amino-N,N-Dimethylaniline Oxalate
    cas_number 33321-14-9
    molecular_formula C8H12N2·C2H2O4
    molecular_weight 238.25 g/mol
    appearance Light brown to brown powder
    solubility Soluble in water
    melting_point 176-180°C (decomposes)
    storage_conditions Store at room temperature, in a tightly closed container, away from light
    synonyms 4-(Dimethylamino)aniline oxalate, N,N-Dimethyl-1,4-benzenediamine oxalate
    purity Typically ≥98%
    hazard_class Irritant
    usage Intermediate for dyes and chemical synthesis

    As an accredited 4-Amino-N,N-Dimethylaniline Oxalate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, 25 grams, sealed with a screw cap, featuring a printed hazard label and product information in black text.
    Shipping 4-Amino-N,N-Dimethylaniline Oxalate is shipped in a tightly sealed container, protected from light and moisture. It is classified as a chemical substance and must be handled following relevant safety regulations. Proper labeling and documentation are included, with transit under standard temperature conditions unless otherwise specified by the manufacturer’s guidelines.
    Storage Store 4-Amino-N,N-Dimethylaniline Oxalate in a tightly sealed container, protected from light and moisture, in a cool, dry, and well-ventilated area. Keep away from incompatible substances such as strong oxidizers and acids. Ensure storage under chemical safety protocols with appropriate labeling, and avoid exposure to direct sunlight or sources of ignition. Regularly check for signs of degradation or contamination.
    Application of 4-Amino-N,N-Dimethylaniline Oxalate

    Applications of 4-Amino-N,N-Dimethylaniline Oxalate in Industrial Manufacturing

    4-Amino-N,N-Dimethylaniline Oxalate serves as a critical raw material in several industrial sectors. Our factory supplies this material direct-to-producer for incorporation into established processes, with controlled specifications supporting high yields and downstream compliance. Below are the principal application tracks structured by real-world use, process practices, and regulatory expectations.

    1. Dyes and Pigments – Intermediate for Cationic Dyes

    Producers leverage 4-Amino-N,N-Dimethylaniline Oxalate as a key intermediate in the synthesis of cationic (basic) dyes, particularly for acrylic and polyacrylonitrile fibers. The aromatic amine structure allows direct integration into quaternization reactions, yielding high-tinctorial-strength blue and green dyes. Close control of impurity levels minimizes final product color defects vital for QC in the textile coloration chain. Batches target low salt content and precise amine index range to meet high-purity grade requirements demanded by fiber coloration plants.

    Industry compliance standards

    • REACH (EC) No 1907/2006
    • OEKO-TEX® Standard 100 (restricted substances list)
    • ZDHC MRSL v3.1
    • ISO 9001:2015 Quality Management System

    Typical usage ratio

    • 10–20% by mass of total dye intermediates mix, depending on desired shade intensity and target molecular structure. Formulators adjust input within this range based on downstream dyestuff solubility and lightfastness requirements.

    Downstream process integration

    • Introduced post-nitrosation and reduction steps, directly reacted under controlled temperature conditions in closed reactors during the formation of basic dye bases. Oxalate form allows lower dust generation and precise charge control.

    Final product types

    • Cationic acrylic fiber dyes (blue and green range)
    • Basic paper dyes
    • Printing inks for textiles
    • Direct-use pigment pastes for copolymer fiber blends

    2. Pharmaceutical Impurity Marker Synthesis

    Major pharmaceutical manufacturers employ this compound as a precursor in analytical synthesis, specifically for impurity reference standards required in API quality and stability studies. The amine group offers diverse points for aromatic substitution, useful in preparing potential degradation products or identification markers per regulatory validation plans. During the synthesis of analytical standards, materials must conform to targeted impurity limits, and all process steps demand strict documentation for traceability.

    Industry compliance standards

    • USP–NF General Chapters (Residue Limits)
    • ICH Q3A(R2) – Impurities in New Drug Substances
    • 21 CFR Part 211 – cGMP for Finished Pharmaceuticals
    • ISO 17034:2016 for Reference Material Producers

    Typical usage ratio

    • Used in µmol to mmol scale per batch, adjusted according to analytical detection limit requirements. Formulators calculate precise input for N-aryl impurity analog development or stress testing batches.

    Downstream process integration

    • Added in the initial stages of small-molecule derivatization, prior to chromatography separation, enabling preparation of trace-level analogs and validating impurity peaks against API samples.

    Final product types

    • Pharmaceutical reference standards
    • Drug impurity analytical kits
    • Process validation markers for QC labs
    • Stability study reference mixtures

    3. Photo-Developer Formulation for Lithography

    In advanced photo-lithography, especially for PCB fabrication and microelectronics, producers utilize this compound as a component in photo-developer blends. Its electron-donating amine function aids in optimizing developer reactivity toward image reversal and contrast. Factories require rigorous control of metallic and organic trace impurities, as even low-level contaminants can impact line edge roughness and yield. Formulators often blend the oxalate form with proprietary stabilizers for wet-process stability and safety.

    Industry compliance standards

    • IPC-4101D Base Material for Rigid and Multilayer PCB
    • SEMI S2-1105 Environmental, Health, and Safety Guideline
    • RoHS Directive (2011/65/EU)
    • SCCS/1617/19 for purity in chemical mixtures used in consumer electronics

    Typical usage ratio

    • 5–17% solution strength relative to carrier solvent, adjusted per resist thickness and pattern resolution target. Technician calibrates each batch via titration and pilot panel testing.

    Downstream process integration

    • Integrated following resist exposure, introduced into automated developer baths as one component of multi-step developer sequence. Strict monitoring assures minimal carryover and controlled pH window.

    Final product types

    • Printed circuit boards (PCBs) for telecommunications
    • High-resolution photomasks for semiconductors
    • Microfluidic chip substrates
    • Photoresist remover formulations for industrial cleaning

    4. Chemical Reagent for Analytical Laboratories

    Certified reagent manufacturers blend this material into colorimetric reagent kits, analytical standards, and test solutions for industrial water, feedstock, and trace amine determination. Its reactivity in diazotization and azo coupling enables rapid formation of quantifiable color complexes, crucial for laboratory QC and regulatory testing. Batches destined for the analytical market require trace element certification with strict batch-to-batch reproducibility to prevent false results in end-user protocols.

    Industry compliance standards

    • ISO 17025:2017 (Testing and calibration laboratories)
    • ASTM D6299 (Quality System in Analytical Laboratories)
    • EPA 40 CFR Part 136 (Water Analytical Methods)
    • European Pharmacopoeia 2.2.2 (Absorption Spectrophotometry)

    Typical usage ratio

    • 0.02–0.15% w/w in analytical reagent mixtures, set based on calibration curve requirements and detection thresholds for the test type. Chemists define ratio via round-robin validation study.

    Downstream process integration

    • Used during preparation of azo dye test reagents, added as the amination agent in single-use or long-life color development vials. Integrated into kit packing lines for QC lot registration.

    Final product types

    • Field test kits for aromatic amines
    • Colorimetric cuvette solutions
    • Trace impurity standards for feedstock analysis
    • Analytical test panels for industrial water treatment

    5. Specialty Chemical Synthesis for Photographic Chemicals

    Producers in the photographic chemicals sector utilize this material in the formulation of image developers and stabilizers for silver-based film processing. The aromatic amine group participates in redox reactions controlling latent image amplification and background clearing. Raw material quality is tested for trace metal content and redox-active impurities to prevent fogging and avoid downstream batch scrap. Producers employ sealed-system charging for safety due to the sensitivity of film emulsions to amine variation.

    Industry compliance standards

    • ISO 18902:2013 – Photographic films and papers safety
    • ANSI/NAPM IT9.11–1993 (Imaging Materials, Storage, and Handling)
    • FDA 21 CFR Part 1330 (Chemical labeling for photographic processing)
    • EN IEC 60335 for chemical safety in processing equipment

    Typical usage ratio

    • 0.5–4% of total developer volume per recipe, varied based on film type, process cycle, and emission limit standards. Technicians confirm actual addition by batch QC titration.

    Downstream process integration

    • Charged at developer make-up stage, before mixing with silver halide solution. Factories monitor pH and redox potential to achieve target image profile upon film exposure and fix stages.

    Final product types

    • Film developer concentrates
    • Stabilizers for black-and-white photographic processing
    • Ancillary process chemicals for imaging labs
    • Specialized contrast enhancers for scientific film instruments
    Free Quote

    Competitive 4-Amino-N,N-Dimethylaniline Oxalate prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Introducing 4-Amino-N,N-Dimethylaniline Oxalate: Insights from a Manufacturer’s Perspective

    Our Hands-On Experience with 4-Amino-N,N-Dimethylaniline Oxalate

    4-Amino-N,N-Dimethylaniline Oxalate, known throughout the industry for its role as an intermediate in organic synthesis, has shown its value across diverse fields. Over years running production lines, controlling quality, and responding to shifts in customer needs, we've seen this compound anchor itself as a dependable choice, especially for those working at the intersection of dyes, analytical chemistry, and certain kinds of specialty reagents. Each batch taught us something new about consistency, handling, and the preferences of chemists and process engineers who rely on us.

    Specifications That Matter on the Factory Floor

    We learned quickly that meeting published standards does not always tell the whole story. Chemists demand specifications rooted in real experiences, not just catalog numbers. In our manufacturing environment, we prioritize purity that consistently reaches 98% or above, as lower grades often trigger downstream purification or quality issues. Controlled particle size and free-flowing texture help prevent clumps and dosing errors during scaling. The product remains stable under typical storage and transportation conditions, a quality we verify with every shipment that leaves the plant.

    Producing and Handling the Compound

    It takes technical know-how and a careful eye to produce 4-Amino-N,N-Dimethylaniline Oxalate at scale. The process is sensitive to moisture since the oxalate salt can pick up water if exposed for too long. Lab and pilot-scale production taught us that even slight deviations in humidity control can lead to caking, a challenge addressed by tight packaging and strict monitoring of warehouse environments. We consistently invest in staff training and robust lab equipment to minimize human error, which, in an operation based on precise chemical transformations, pays for itself many times over in reliability and safety.

    Application Knowledge: Our View at the Source

    Our technical staff frequently field questions from clients about what sets 4-Amino-N,N-Dimethylaniline Oxalate apart. Its primary use stems from its status as a useful intermediate. Chemists in colorant development select it for synthesizing dyes and pigments due to the structure, which allows for further substitutions. Analytical labs favor it as a reagent in specialized colorimetric assays. Some research groups apply it as a building block for exploring novel pharmaceuticals or specialty chemicals. We do not just ship drums and hope for the best; many end users request advice on process conditions, expected yields, and troubleshooting. Because we stay close to both the chemistry and the feedback from the field, these conversations feel less abstract and more grounded in practice.

    Comparing the Oxalate Salt with Other Forms

    Over the years, teams engage us with comparisons between the oxalate salt and alternative forms like the hydrochloride or free base. The oxalate salt handles better in many lab and factory environments due to its lower volatility and more manageable dusting. Processes that involve precise stoichiometry benefit from the salt’s solubility profile. On several occasions, powder handling—often overlooked in the theoretical literature—has made or broken a process. The oxalate version features more controlled static properties and tends not to clump in hoppers or feeders, a benefit discernible only once you have spent time on a processing floor watching operators struggle with a powder that refuses to flow.

    In dye synthesis, the oxalate salt can improve color consistency because of its behavior in solution, allowing better predictability batch after batch. Other forms can introduce variables like fluctuating free amine content or water uptake. Chemists focused on reproducibility appreciate the reliability that comes from using the oxalate over alternatives. These points come up often in conversations with process engineers who spend their days fighting variability.

    Lessons from Quality Control: Chasing Consistency

    Quality control is not just a checkbox for us. We learned that a single off-spec lot can disrupt schedules or disrupt a customer’s downstream process. At the plant level, each stage of synthesis receives in-process checks not because regulators ask for it, but because the consequences of inattention accumulate rapidly. Thin-layer chromatography and NMR spectrometry verify structure, but we also track subtle changes in appearance, from bulk color to the tiniest shift in texture. Sometimes, the feedback from a regular customer—a shift in dissolution time or a persistent haze in solutions—uncovers issues not apparent in lab-scale QC. Factoring real-world handling experience into our specifications remains a key element of every product we offer.

    Field Feedback and Continuous Improvement

    In working with R&D teams and large-scale users, ongoing feedback improves our process more than any isolated lab result ever could. Instances where a client encountered clumping during seasonal humidity swings spurred us to test anti-caking procedures and refine our packaging. Occasional reports of unexpected byproducts from unfamiliar synthetic routes prompted us to launch stability studies, tracing sources of contamination back to minor fluctuations in reagents or temperature. Correcting for these in real-time, not just after the fact, establishes trust with buyers who count on us to help keep their lines productive.

    Managing Safety and Regulatory Expectations

    Chemical manufacturing occurs in a complex regulatory environment. 4-Amino-N,N-Dimethylaniline Oxalate, as an aromatic amine salt, faces scrutiny regarding worker health and environmental impact. Our teams found that early investment in closed-system handling, dust collection, and personal protective equipment actually pays off through lower incident rates, smoother audits, and fewer production interruptions. Cutting corners to reduce costs only shifts problems down the line and damages relationships with both workers and customers. By maintaining transparency in handling practices, we help our partners anticipate their own regulatory hurdles and avoid costly oversights.

    Differences That Affect Outcomes: Our Perspective

    Purchase decisions often focus on purity and cost, but daily manufacturing experience shows that batch homogeneity and consistency in particle distribution play a bigger role in process efficiency. Minor differences between lots can lead to blocked lines or uneven color distribution in dyes, which never look good in high-end applications. Our painstaking approach to process optimization—by controlling cooling rates, mixing speed, and filtration pressure—leads to finished products that behave the same way every time. Those who have processed competing materials tell us that our tighter control over these physical characteristics delivers fewer surprises. Smoother flows, more reliable metering, and predictable solubility support operations aiming for high yield and reduced downtime.

    Supporting Users from Pilot to Industrial Scale

    Lab-scale chemists and process engineers face different challenges from plant managers running bulk synthesis. In smaller setups, solubility and storage often matter most. Technicians want assurances that the powder pours clean, stays dry, and does not interfere with glassware cleaning. In our early days, returning to the lab with feedback from operators often forced us to revisit granulation and packing choices. In larger settings, handling efficiency and process yield dominate conversations. Every gram lost to dusting or sticking represents increased costs and reduced throughput. By focusing on real-world handling dynamics rather than just lab analytics, we help both small and large users avoid common pitfalls. Our willingness to swap stories and field specific technical questions grows out of years spent listening to both sides of the scale.

    Reducing Environmental Impact with Smarter Production

    Our commitment to responsible manufacturing extends beyond compliance. We evaluate solvent usage, pursue recycling programs, and adjust our synthesis where possible to minimize waste. Environmental audits can cause stress, but proactive investment pays off. Efforts to reduce off-gassing during drying and to minimize transport packaging reduce both risk and material costs. Clients who share sustainability goals respond positively when we present data showing a meaningful drop in energy or solvent consumption per kilogram of product. Our goal focuses on supporting customer innovation without increasing environmental burden. These lessons, learned through years at the production site, shape every process improvement initiative we launch.

    Challenges and Solutions in Secure Transport

    Transporting chemical intermediates sometimes involves longer routes, variable climate control, and an unpredictable chain of custody. We select packaging materials and sealing methods after studying both mechanical transport risks and common warehouse storage pitfalls. Early on, we faced returns and customer complaints stemming from moisture intrusion and product agglomeration. Now, we seal every batch in moisture-proof bags and reinforce drums for shipping stress. Frequent communication with logistics partners ensures that handling instructions are followed and deviations get reported back to us. Real improvement came after visiting our partners’ loading docks and seeing our materials move through real-world distribution channels.

    Why Trust Grows from Experience

    Buyers face a crowded field of suppliers, all promising top quality and steady supply. Over time, it is not the boldest claims that win trust, but how quickly and effectively a partner responds to setbacks and solves real problems. In our experience, offering technical support and troubleshooting not only builds confidence, it educates our team about practical needs not visible from the synthesis vessel or the office. The value of a responsive chemical producer lies as much in their ability to adapt a process as it does in the technical details printed on a certificate of analysis. Honest communication about supply chain interruptions, recurring batch variations, or changing regulatory status for a compound like 4-Amino-N,N-Dimethylaniline Oxalate matters even more than consistency in any one batch.

    Process Innovation Shapes Product Value

    Continuous process optimization keeps us competitive, but real breakthroughs often originate out of needs articulated by end users. Equipment upgrades for better temperature control, new drying methods to reduce clumping, and packaging innovations directed at regional storage conditions come from active dialogue with people actually handling the product. By sharing performance metrics and tracking process deviations, we can demonstrate improvements not just for our own records but for every customer whose operations depend on smooth and dependable inputs.

    Navigating Cost Pressures Without Compromising Standards

    Cost fluctuations for starting materials and energy inputs challenge chemical producers. We have learned that short-term savings achieved by substituting lower-quality reagents or trimming testing steps produce much greater long-term costs. Our approach keeps to strict sourcing standards, even during periods of fluctuating market prices. Long-term relationships with trusted suppliers, combined with regular audits of raw material lots, prevent surprises. As a result, our partners spend less time troubleshooting and more time focusing on results. While competitive pricing remains part of every conversation, our approach focuses on total value—time saved, fewer rejected batches, easier handling, and lower maintenance costs—rather than on the price per kilogram alone.

    Educating New Users and Avoiding Common Pitfalls

    Some of our most valued relationships began as problem-solving sessions for new customers who inherited unfamiliar processes or switched from a different material type. We keep files detailing common pitfalls: excessive moisture leading to clumping, improper dosing because of variable powder density, or incompatible mixing regimes with certain solvents. These files do not sit idle—they serve as the basis for training new staff, sharing with buyers, and fielding technical support queries. The aim involves reducing wasted effort, lost product, and rework, all of which improve the reputation of both the customer and the producer. Suppliers who hide behind silence in hopes that users will not notice a problem tend to lose clients quickly.

    Future Trends: Anticipating Evolving Requirements

    Changes in downstream industries drive constant evolution in both product requirements and production standards. Whether driven by cosmetic, dye, or specialty chemical applications, end users demand higher purity, more granular quality reporting, and traceable supply lines. We stay ahead by scanning for new industry standards before they get enforced, investing in both analytics and documentation, and honoring requests for sample validation. Sometimes these trends require updating handling guidelines or investing in new containment systems years before regulations demand them. Forward-looking clients value this attitude since it supports their own compliance and secures continued innovation.

    The Manufacturer’s Commitment

    Standing behind every shipment of 4-Amino-N,N-Dimethylaniline Oxalate, our team brings decades of experience not only in the art of chemical synthesis but also in adapting to changing guidelines, applications, and client priorities. We succeed by keeping every member of the team involved, from operators who spot handling trends early to managers who track lot performance and field customer complaints. This blend of technical depth, humility before the process, and commitment to real-world needs shapes every improvement, every batch, and every relationship we build.

    Chemists, engineers, and process managers who work with us find more than a shipping document and generic certificate—they gain a partner invested in long-term reliability, grounded in actual factory and laboratory experience. This product introduction, drawn from direct involvement in the production, use, and optimization of 4-Amino-N,N-Dimethylaniline Oxalate, reflects what we have learned by walking plant floors, running synthesis in changing seasons, and listening intently to the needs of partners from every corner of the chemical industry.