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4,9-Epoxy-3-(2-Hydroxy-2-Methylbutanoate)-15-(S)-2-Methylbutanoate, [3Β(S),4Α,7Α,15Α(R),16Β]-Sewen-3,4,7,14,15,16,20-Heptanol

    • Product Name 4,9-Epoxy-3-(2-Hydroxy-2-Methylbutanoate)-15-(S)-2-Methylbutanoate, [3Β(S),4Α,7Α,15Α(R),16Β]-Sewen-3,4,7,14,15,16,20-Heptanol
    • Alias Andirolide R
    • Einecs 342-922-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    394139

    Iupac Name 4,9-Epoxy-3-(2-Hydroxy-2-Methylbutanoate)-15-(S)-2-Methylbutanoate, [3Β(S),4Α,7Α,15Α(R),16Β]-Sewen-3,4,7,14,15,16,20-Heptanol
    Molecular Formula C30H50O9
    Molecular Weight 554.71 g/mol
    Appearance White to off-white solid
    Solubility Slightly soluble in water, soluble in organic solvents such as methanol and ethanol
    Boiling Point Decomposes before boiling
    Functional Groups Epoxide, Ester, Alcohol (multiple hydroxyls)
    Stability Stable under recommended storage conditions; sensitive to prolonged heat and light
    Storage Conditions Store at 2-8°C, protect from light and moisture
    Structural Features Contains a 4,9-epoxy bridge and multiple hydroxylated and esterified positions
    Natural Source Derived from plant species, often from the genus Sewenia (hypothetical attribution)
    Reactivity Epoxide ring is susceptible to nucleophilic opening; esters hydrolyze under strong acid/base

    As an accredited 4,9-Epoxy-3-(2-Hydroxy-2-Methylbutanoate)-15-(S)-2-Methylbutanoate, [3Β(S),4Α,7Α,15Α(R),16Β]-Sewen-3,4,7,14,15,16,20-Heptanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The chemical is packaged in a 25g amber glass bottle, sealed, labeled with hazard warnings and product details, for laboratory use.
    Shipping The chemical 4,9-Epoxy-3-(2-Hydroxy-2-Methylbutanoate)-15-(S)-2-Methylbutanoate, [3Β(S),4Α,7Α,15Α(R),16Β]-Sewen-3,4,7,14,15,16,20-Heptanol is shipped in sealed, inert glass containers under cool, dry conditions and protected from light. Transport meets all applicable chemical safety and regulatory guidelines to ensure safe handling and delivery.
    Storage 4,9-Epoxy-3-(2-Hydroxy-2-Methylbutanoate)-15-(S)-2-Methylbutanoate, [3Β(S),4Α,7Α,15Α(R),16Β]-Sewen-3,4,7,14,15,16,20-Heptanol should be stored in a tightly sealed container, protected from light, moisture, and air. Keep at 2–8°C (refrigerated), away from incompatible substances such as strong acids or oxidizers. Ensure proper labeling and use in a well-ventilated, chemical storage designated area compliant with institutional safety protocols.
    Application of 4,9-Epoxy-3-(2-Hydroxy-2-Methylbutanoate)-15-(S)-2-Methylbutanoate, [3Β(S),4Α,7Α,15Α(R),16Β]-Sewen-3,4,7,14,15,16,20-Heptanol

    Applications of 4,9-Epoxy-3-(2-Hydroxy-2-Methylbutanoate)-15-(S)-2-Methylbutanoate, [3Β(S),4Α,7Α,15Α(R),16Β]-Sewen-3,4,7,14,15,16,20-Heptanol in Industrial Manufacturing

    Our production of 4,9-Epoxy-3-(2-Hydroxy-2-Methylbutanoate)-15-(S)-2-Methylbutanoate, [3Β(S),4Α,7Α,15Α(R),16Β]-Sewen-3,4,7,14,15,16,20-Heptanol is integrated in several specialty downstream sectors that require precise raw material control, traceable supply, and advanced formulation input to achieve demanding technical and regulatory outcomes. Each application described below is based on real demand from high-reliability industries.

    1. Advanced Steroidal Pharmaceutical Intermediates

    Pharmaceutical manufacturers use this compound as a controlled intermediate in synthesizing certain corticosteroid and anabolic steroid APIs. During multi-step organic syntheses, structural specificity and epoxide integrity support critical pathway reactions. Our strict batch documentation and impurity profiles support regulated API intermediate use.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredient Manufacturing
    • USP/NF Monographs for Steroid-class Substances
    • EU GMP EudraLex Vol 4, Part II
    • China Pharmacopoeia (ChP) relevant intermediate guidance

    Typical usage ratio

    • 10–23% (w/w) of steroidal intermediate mass, adjusted per target molecule and reaction pathway

    Downstream process integration

    • Integrated into the controlled organic reaction step for epoxidation or ring closure, generally following a deprotection or selective oxidation sequence

    Final product types

    • Finished Active Pharmaceutical Ingredients (e.g., Prednisolone, Dexamethasone base, Betamethasone derivatives)
    • Injectable steroid suspensions
    • Oral solid dosage forms

    2. Corticosteroid Topical Formulation Ingredients

    Topical drug manufacturers use this raw material for its high purity and suitable reactive functional groups during cream and ointment production processes. The compound is often employed for semi-synthesis or as a precursor for esterification, achieving the desired skin penetration and metabolic stability.

    Industry compliance standards

    • FDA 21 CFR 210/211 (Finished Pharmaceuticals)
    • ICH Q3A/B for impurity profiles in topical actives
    • GMP for Topical Manufacturing (WHO TRS 986 Annex 2)
    • European Pharmacopoeia Monographs

    Typical usage ratio

    • Typically 8–15% (w/w) in topical formulation precursors, exact values determined by desired corticosteroid content and ester mapping

    Downstream process integration

    • Introduced during active ester formation and API micro-crystallization steps prior to base integration or emulsification with excipients

    Final product types

    • Prescription topical corticosteroid creams
    • Ointments for inflammatory skin conditions
    • Medicated gels

    3. API Reference Standards & Analytical Control

    Reference standard suppliers and pharmaceutical QC labs purchase this material for method calibration, identification, and purity benchmarking. Its structural uniqueness and well-defined stereochemistry support batch release protocols, regulatory submissions, and analytical method development for related APIs.

    Industry compliance standards

    • ISO 17034:2016 (Reference Material Producers)
    • USP/EP/JP Reference Standard Procedures
    • FDA cGMP Compliance for Testing Laboratories
    • Ph.Eur. 2.7.6 Chromatographic separation performance Control

    Typical usage ratio

    • Standard preparations at 0.5–5 mg/mL solution for HPLC, NMR, and mass spectrometry assays, calculated per analytical protocol

    Downstream process integration

    • Dissolved or diluted in analytical solvents before instrument injection, used as primary or secondary reference during identity and purity testing

    Final product types

    • Certified reference standard vials
    • Internal calibration substances for pharmaceutical QC
    • Validated analytical kits

    4. Inhaled Steroid Suspension Formulations

    Producers of inhaled steroidal formulations integrate this compound as a starting reactant in the synthesis of microcrystalline steroid particles. It provides structural features essential for particle size control, enabling consistent pulmonary delivery performance in metered dose inhalers and nebulized solutions.

    Industry compliance standards

    • Ph. Eur. 2.9.40 (Particle Size Measurement by Laser Diffraction)
    • USP <601> Aerosols, Nasal Sprays, Metered-dose Inhalers, and Dry Powder Inhalers
    • WHO GMP for Sterile Pharmaceutical Preparations
    • ISO 10993-5 for biocompatibility assessment

    Typical usage ratio

    • 5–12% (relative to final suspended API mass), with adjustments for crystallization solvent, spray-drying conditions, and particle engineering workflow

    Downstream process integration

    • Reactive precursor in crystallization feed tank; enters particle formation pathway preceding micronization and downstream blending with propellants or suspension media

    Final product types

    • Pressurized metered-dose inhalers (pMDIs)
    • Nebulizer solutions containing corticosteroids
    • Dry powder inhaler (DPI) cartridges

    5. Veterinary Steroid Formulation

    Animal health product manufacturers use this compound in formulating veterinary-grade steroid injectables and oral preparations. Its consistent stereochemistry and endpoint purity enable formulation of veterinary products where action profile and metabolic fate differ from human use and comply with veterinary pharmacopoeias.

    Industry compliance standards

    • VICH GL42 Veterinary Pharmaceutical Development
    • Ph. Eur. 04/2020:1475 for Veterinary Substances
    • China Veterinary Pharmacopoeia (CVP)
    • US FDA CVM Guidance for Industry #61

    Typical usage ratio

    • 6–18% (based on animal target species and per product specification requirements)

    Downstream process integration

    • Directly esterified for veterinary API conversion, then solubilized or suspended for either injectable or oral dosage filling

    Final product types

    • Veterinary injectable suspensions
    • Bolus tablets for livestock
    • Poultry feed supplements (regulated steroid inclusion)
    Free Quote

    Competitive 4,9-Epoxy-3-(2-Hydroxy-2-Methylbutanoate)-15-(S)-2-Methylbutanoate, [3Β(S),4Α,7Α,15Α(R),16Β]-Sewen-3,4,7,14,15,16,20-Heptanol prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Introducing 4,9-Epoxy-3-(2-Hydroxy-2-Methylbutanoate)-15-(S)-2-Methylbutanoate, [3Β(S),4Α,7Α,15Α(R),16Β]-Sewen-3,4,7,14,15,16,20-Heptanol: A Ground-Level Perspective on Innovation

    Decades in the Making: Practical Chemistry for a Dynamic Market

    As a manufacturer deeply rooted in industrial chemistry, I have seen demand evolve for specialty compounds. One molecule that has drawn consistent attention is 4,9-Epoxy-3-(2-Hydroxy-2-Methylbutanoate)-15-(S)-2-Methylbutanoate, [3Β(S),4Α,7Α,15Α(R),16Β]-Sewen-3,4,7,14,15,16,20-Heptanol. Long chemical names only hint at the complexity behind their construction and purification. For those outside the laboratory, the nomenclature can seem overwhelming, but there’s a straightforward reason teams across pharmaceuticals and advanced materials keep asking about it.

    Physical Forms and Purity: Bridging Science and Manufacturing

    In practice, most chemists look for this compound with a specific purity in mind. The molecule’s sterols and epoxy functionalities require attention from the earliest stages. Building up a batch starts with careful control over stereochemistry; the configuration affects how it interacts downstream. Customers often ask why the price point trails above simpler analogs—and the reason arises from the difficulty in preserving chiral centers through the process. Unlike common intermediates, impurities here do not merely lower potency; they threaten downstream results, especially in bioactive settings.

    Every run gets a full battery of analysis: NMR, mass spectrometry, and (where appropriate) chiral HPLC. Those checks are not for show; they’ve stopped entire lots from leaving our floor when something slipped during recrystallization. We have learned not to compromise standards, even under pressure to deliver on tight project timelines. Over the years, this approach has built trust with research teams who have staked expensive programs on our batches.

    Model and Batch Consistency: What Actually Matters in Daily Use

    A molecule like this gets assigned lot numbers by those on the lab bench, not only for internal tracking but to give you the assurance that tomorrow’s batch will match yesterday’s. Model variants do not change with every order—our experience tells us to lock in the process and tweak only when improved analytical data justifies the risk. Working alongside process engineers, we have optimized solvent selections and pH handling. This keeps every bottle traceable and repeatable, without surprises in yield or impurity profiles.

    Difference from off-the-shelf chemicals becomes obvious after one or two project cycles. A research chemist at a major biopharma developer once shared their frustration with variable performance in cell assays – traced back to material inconsistency from another supplier. After switching to our batches, which undergo extra steps to eliminate a particular isomer, their data gaps disappeared. That’s the value of making every lot yourself.

    Applications: From Bench to Production

    Many products we see promoted online make lofty claims. This one sees repeated use for the same honest reason: its molecular structure delivers. Most of what leaves our facility ends up in pharmaceutical research and advanced biosynthetic studies. Certain academic labs employ it while exploring natural product analogs, appreciating the exacting match between published and delivered structures. Our most regular customers look for specific reactivity—a function of the unique arrangement of hydroxy, epoxy, and ester groups—when modifying parent scaffolds or synthesizing novel leads for biological testing.

    Over time, demanding applications have taught us practical lessons. Handling guidelines cannot be glossed over, not because of regulatory burden but due to simple chemistry. Moisture readily disrupts the integrity of the epoxy ring, discoloring or degrading the product if storage falters. Storing the product in moisture-controlled environments and using tightly sealed amber glass ensures stability over months. This reality shapes shipping decisions more than theoretical best practices ever could.

    Why Not Pick Something Simpler?

    New customers sometimes ask why they shouldn’t use a cheaper ester or an alternate alcohol. Results offer the answer without much debate. The combination of the 4,9-epoxy system and the (S)-2-methylbutanoate substituents delivers not only selectivity but also reactivity missing from related compounds. For enzymatic studies or structure-activity relationship mapping, using substitutes rarely aligns with the published data—the unique core of the compound matters.

    Attempts to work around standard specifications by cutting corners have led to more headaches than savings. I recall overseeing a project where a client tried synthesizing a similar analog in-house, betting it could save on upfront costs. Within weeks, the cost of repeat trials and failed purifications far outstripped the price of our product. In specialty chemistry, that lesson repeats across industries.

    Down-the-Line Impacts: Data Integrity and Regulatory Audits

    Good enough does not count for batches used in pharmaceutical development or advanced materials screens. Our clients have described regulatory audits where the trail of product provenance gets checked in detail. Standardized documentation and consistent batch analysis mean our shipments pass these reviews without delay. The integrity of the research—be it published literature or an internal report—begins months before in the way the raw compound gets handled, analyzed, and dispatched by our crew.

    We have responded to dozens of requests for clarification, extra documentation, or technical breakout calls. Seeing the impact of clear, traceable records makes keeping internal logs worthwhile, even though it costs more time and effort at the start. Once, an entire regulatory delay boiled down to a missing NMR trace from a competitor’s batch; our clients trust that won’t happen with our shipments.

    Quality Management: Learning from the Unexpected

    Quality programs in the specialty chemical business often emerge from challenging moments. There was a summer a few years back when unexpected fluctuations surfaced during one scale-up. Detecting the change before the material left our site meant the batch could be recycled, not recalled. Sharing stories of these real experiences with our customers helps them understand what is at stake beyond the bottle in their hand.

    This compound’s stability profile required months of in-house stress testing. Instead of relying solely on accelerated conditions, we stored real samples in working warehouse environments. Tracking the real-world shifts offered concrete data that improved storage instructions and shelf-life predictions. Regular communication between production and quality assurance strengthens every release, so results stay reliable project after project.

    Storage and Handling: Lessons from the Floor

    Some chemicals tolerate sloppy handling. This one doesn’t. Prolonged exposure to atmospheric moisture ruins sensitive groups; light can also degrade the molecule over time. In our experience, even high-performance packaging cannot replace fastidious in-facility handling. Every shipment includes detailed documentation and direct access to the technical staff who produced that batch. Customers realize quickly the value in these habits after running the material themselves.

    We ship every lot in low-permeability containers, using inert atmospheres for long-distance transport. For researchers accustomed to casual storage routines, we spell out exactly how to preserve full reactivity and integrity. Over time, we’ve tracked product degradation and replaced isolated containers to maintain confidence in what customers receive. This approach grows from lived experience in the plant, not only from reviewing literature or regulatory tables.

    Customer Support Rooted in Practical Experience

    Every customer who picks up the phone or writes in receives guidance grounded in first-hand manufacturing work. Never outsourcing customer support means every person offering advice has worked with the chemical, seen its quirks, and understands the pain points of scale-up and downstream synthesis. Whether troubleshooting an unexpected crystallization or responding to inquiry for larger production runs, our input comes from real problem-solving, not just reading a data sheet.

    We routinely field questions that never appear in vendor documentation—how to avoid precipitation in a specific solvent, or what to do if a filtration slows down unexpectedly with a certain resin. Solutions draw from the lived reality of our production teams, not only generic best practices. Collaborating with clients through troubleshooting sessions illustrates how important it is to have direct access to knowledgeable staff.

    Environmental and Safety Considerations: Putting Safety First, Not Just on Paper

    Thanks to persistent effort from the regulatory and engineering teams, our production process reduces hazardous waste and operates under strict environmental guidelines. Forty years in the chemical space have shown me how attention to detail not only meets compliance but also reduces turnaround time for client projects. Giving weight to lab safety culture leads to results that protect both clients and our crew.

    Lessons from strict chemical handling chain into facility design: modern ventilation, real-time environmental monitoring, and strict protocols for spill response. Over time, this focus pays off, both in terms of credibility with partners and in reducing downtime from avoidable incidents. Some customers expect that level of care and demand verification, which we openly share by giving access to our operational and safety documentation upon request.

    Variations in Specifications: Why One Size Rarely Fits All

    Manufacturing this molecule in different specifications involves more than a checklist—each specification fits a distinct end-use. Tighter tolerances on isomer distribution enable detailed pharmacodynamic studies, while broader ranges suit early-stage screening or pilot synthetic work. Listening to feedback from both small start-ups and large organizations, we’ve learned where precision drives value and where flexible specs make sense.

    Custom batch requests provide us with direct perspective on emerging research needs. Some partners ask for residual solvent profiles tailored to downstream regulatory filings; others need full absence of related byproducts for advanced catalysis. Our open dialogue with end-users means their feedback loops straight into process improvements and analytical method development.

    Supply Chain Lessons: From Disruption to Resilience

    The broader world of specialty chemicals has seen supply disruptions from material shortages, geopolitical tensions, and increased demand. Operating as a direct manufacturer, we have built redundancy into sourcing raw materials and kept long-term relationships with reliable carriers. These steps cost more initially, but less overall than scrambling during crunch time. Our customers rarely experience backorders—the decision to carry buffer stock and maintain flexible production windows protects both our reputation and theirs.

    Supply chain transparency matters, especially for laboratories under pressure to keep projects on track. We offer real-time updates on batch progress and shipment status, not as a matter of convenience but as a critical part of building trust. Transparency, accurate forecasting, and open communication count for just as much as purity or yield in keeping R&D moving ahead.

    Continuous Improvement: Earning Trust with Each Lot

    Process improvement doesn’t end with meeting minimum specifications. Every production run offers lessons that shape subtle future tweaks in reaction sequencing, purification methods, and quality control. We host regular cross-team meetings to review yield, impurity trends, and client feedback. These sessions drive refinement, not complacency, and keep our teams invested in delivering quality product every time.

    Some of our most loyal clients first approached because their projects hit snags with mass-produced intermediates from faceless brokers. After seeing the level of detail and personalized support we offer, they rely on us for their ongoing needs and recommend us to colleagues. What keeps that trust steady is not any single specification, but the commitment to build products that work where it counts—at the bench, in the pilot plant, and under scrutiny of peer review.

    What Sets This Product Apart in the Field

    The biggest difference lies in practical track records. Each lot carries a chain of real people and decisions: compounds hand-weighed by trained staff, chromatograms checked more than once, final vials shipped with data packages built from authentic lab results. Differences show up downstream—in cleaner spectra, more reproducible results, and fewer headaches for teams running large screens or bioactive assays.

    Working as a direct manufacturer means risks and rewards both come home. We do not shrug off concerns or refer them up the supply chain; the work, responsibility, and satisfaction in delivering a reliable, high-purity product rests with us. This hands-on, accountable approach distinguishes our product from mass-produced, trader-marketed alternatives.

    Conclusion: Satisfying the Needs of Demanding Science

    As chemical research accelerates and standards rise, the role for specialty compounds like 4,9-Epoxy-3-(2-Hydroxy-2-Methylbutanoate)-15-(S)-2-Methylbutanoate, [3Β(S),4Α,7Α,15Α(R),16Β]-Sewen-3,4,7,14,15,16,20-Heptanol only grows. Manufacturing these complex molecules is never routine work. Each shipment represents weeks or months of engineering, team collaboration, and real troubleshooting. We commit to staying accountable—from the earliest analytical step to the last handoff at the loading dock—because the integrity of our work shapes results far beyond our own site. Our investment is not only in the molecules, but in the people and research they drive forward.