Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

3,4-Xylenol

    • Product Name 3,4-Xylenol
    • Alias 3,4-Dimethylphenol
    • Einecs 202-423-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    933614

    chemical_name 3,4-Xylenol
    cas_number 95-65-8
    molecular_formula C8H10O
    molecular_weight 122.17 g/mol
    appearance Colorless to pale yellow liquid
    boiling_point 218°C (424°F)
    melting_point −1°C (30.2°F)
    density 1.03 g/cm³ at 20°C
    solubility_in_water 1.6 g/L at 20°C
    flash_point 91°C (196°F)
    odor Phenolic
    refractive_index 1.531 at 20°C

    As an accredited 3,4-Xylenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for 3,4-Xylenol, 500g, features a sealed amber glass bottle with a secure screw cap and hazard labeling.
    Shipping 3,4-Xylenol should be shipped in tightly sealed containers, protected from physical damage and separated from incompatible substances such as oxidizers and acids. Transport in accordance with local and international hazardous material regulations, using proper labeling and safety documentation. Store and ship under cool, dry, and well-ventilated conditions to prevent leakage or vapor release.
    Storage 3,4-Xylenol should be stored in a tightly closed container in a cool, dry, well-ventilated area away from incompatible substances such as oxidizing agents and acids. Protect the chemical from direct sunlight and sources of ignition. Ensure storage area is clearly labeled and that spill containment is in place. Handle with appropriate personal protective equipment to prevent skin or eye contact.
    Application of 3,4-Xylenol

    Applications of 3,4-Xylenol in Industrial Manufacturing

    As a direct manufacturer of high-quality 3,4-xylenol, we supply this versatile intermediate to leading industrial producers across specialist chemical value chains. Our material integrates into established downstream formulations and processes, supporting consistent performance and regulatory compliance from initial raw material stage through to final customer products.

    1. Agricultural Fungicide Synthesis

    In modern agrochemical production facilities, 3,4-xylenol serves as a key phenolic intermediate for formulating targeted fungicidal actives. Producers rely on its aromatic backbone to achieve strong antifungal performance in broadacre and specialty crop protection agents. Raw material quality and traceability directly impact batch reproducibility, compliance with international residue standards, and product registration worldwide.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • REACH (EC) No 1907/2006 Registration
    • EPA 40 CFR Part 180 (US tolerance exemptions for inert ingredients)
    • China National Standard GB 2763 (Maximum Residue Limits for Pesticides in Food)

    Typical usage ratio

    • 5–15% w/w as precursor content, adjusted based on specific fungicide molecule synthesis pathway and regulatory restrictions on phenolic by-product formation

    Downstream process integration

    • Chlorination or etherification reaction of 3,4-xylenol in multi-step synthesis of agricultural active ingredient, followed by formulation into emulsifiable concentrate or wettable powder

    Final product types

    • Triazole-based fungicide technical concentrate
    • Commercial fungicide suspension concentrates (SC)
    • Seed treatment solutions
    • Protective agrochemical spray formulations

    2. Industrial Disinfectants & Phenolic Cleaners

    Disinfectant formulators incorporate 3,4-xylenol as an active germicidal component in medical, institutional, and industrial surface cleaners. The phenolic ring structure delivers effective microbial kill, while enabling compliance with specific biocidal product directives. Dosage depends on targeted spectrum (bacteria, fungi, viruses), required contact time, and regulatory limit values for residual phenols in the end use environment.

    Industry compliance standards

    • EN 1276 (European Standard for bactericidal activity)
    • EPA FIFRA 40 CFR § 158.2200 (US Antimicrobial Products Efficacy Test Standards)
    • China GB 27950-2020 (Disinfectant Safety Technical Specification)
    • Health Canada DIN guidance for disinfectant drugs

    Typical usage ratio

    • 0.2–2.5% w/w in finished aqueous or solvent-based concentrate, varying by formula for intended spectrum and required kill time

    Downstream process integration

    • Direct addition of 3,4-xylenol into aqueous blending and emulsification steps; dissolved into surfactant phase or solvent matrix prior to packaging

    Final product types

    • Hospital surface disinfectant concentrates
    • Institutional germicidal cleaners
    • Phenolic household disinfectant liquids
    • Industrial sanitation fluid blends

    3. Antioxidant Additives in Lubricant Manufacturing

    Lubricant and grease formulators use 3,4-xylenol derivatives as phenolic antioxidants, protecting finished oils from oxidative degradation during extended service intervals. Oxidation inhibitors based on this molecule stabilize mineral and synthetic basestocks, reduce sludge formation, and extend drain intervals, especially under high-temperature and high-shear operating conditions. Adoption depends on compatibility with food-grade or non-food industrial specifications and blend stability.

    Industry compliance standards

    • API 1509 (Engine Oil Licensing and Certification System)
    • ASTM D4951 (Performance of Additive Packages)
    • REACH Annex XVII – Regulation on hazardous substances in lubricants
    • NSF HX-1 (Lubricant components for incidental food contact, if applicable)

    Typical usage ratio

    • 0.5–1.8% w/w in additive package; adjustment according to base oil composition and targeted oxidation resistance specifications

    Downstream process integration

    • Synthesized as antioxidant component and blended with dispersants, detergents, and other performance additives at additive blending stage before final oil compounding

    Final product types

    • Automotive crankcase oils
    • Industrial gear lubricants
    • High-temperature synthetic greases
    • Compressor and hydraulic fluids

    4. Chemical Intermediate for Pharmaceutical Actives

    Advanced pharmaceutical manufacturers utilize 3,4-xylenol as a building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) including certain anesthetics and antiseptics. The phenolic precursor enters tightly controlled GMP-compliant synthesis lines, where strict impurity and residual solvent criteria apply. Downstream conversion requires validated processing methods to achieve API-grade material, maintaining consistent quality for regulatory submission and batch release.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice Guide for APIs
    • USP–NF/Ph. Eur./JP Monographs (where applicable for intermediates and APIs)
    • 21 CFR Part 210/211 cGMP for Finished Pharmaceuticals
    • EU EC No 1901/2006 (Pediatric Regulation, for pediatric APIs containing this phenolic precursor)

    Typical usage ratio

    • Variable: 1–12% mol/mol in reaction mass, depending on synthetic route and desired conversion yield for targeted pharmaceutical molecule

    Downstream process integration

    • Initial reaction step via etherification, halogenation, or amination using 3,4-xylenol, followed by sequential purification steps (including crystallization and column chromatography) in GMP suite

    Final product types

    • API intermediates for anesthetics (e.g. hexylresorcinol derivatives)
    • Pharmaceutical antiseptics/formulated topical solutions
    • Bulk API batches for further tableting or formulation
    • Medical-grade wound cleansers

    5. Resin and Polymer Modifier in Epoxy Systems

    Epoxy resin formulators use 3,4-xylenol as a reactive modifier to tailor molecular crosslinking density and mechanical properties in advanced coatings, adhesives, and composite matrices. This phenolic agent reacts during the prepolymer stage, impacting viscosity, cure rate, and heat resistance of the finished polymer material. Manufacturing precision and trace purity significantly affect product consistency and end-use safety.

    Industry compliance standards

    • ISO 9001 (Quality Management for Resin Production)
    • REACH SVHC guidelines (Europe, for chemical substances in resins)
    • China HG/T 3668 (Technical Conditions of Epoxy Resin)
    • ASTM D1652 (Epoxy Content in Epoxy Resins)

    Typical usage ratio

    • 0.5–3.0% by resin weight, optimized during pilot formulation for targeted thermal and mechanical properties

    Downstream process integration

    • Incorporation into prepolymer mixing step before curing agent addition, enabling chemical grafting onto backbone structure during crosslinking

    Final product types

    • Structural adhesives for automotive and electronics
    • Advanced protective coatings (marine, industrial)
    • Composite materials for aerospace tooling
    • Encapsulation and potting compounds
    Free Quote

    Competitive 3,4-Xylenol prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    3,4-Xylenol: Practical Insights from Our Chemical Plant

    What Our Team Knows About 3,4-Xylenol

    Walking through the synthesis line at our facility, you get a true sense of what it takes to put 3,4-xylenol in the drums. For years, our operation honed its process to deliver consistent, high-quality batches of this vital intermediate. In our hands, 3,4-xylenol is born from robust methylation and selective separation techniques, each step watched over by staff who know the smell, color, and behavior of pure product. The finished material—crystalline, faintly redolent—carries the unmistakable signature of careful chemical handling. Experienced technicians, backed by laboratory screening at every production checkpoint, keep purity locked in, batch after batch.

    3,4-xylenol, often referenced by chemists as 3,4-dimethylphenol, stands out as a key building block. Our daily work with it ends up in products you might never guess: pesticides, disinfectants, resins, and more. Certain applications demand tight adherence to a high level of purity, which clears the way for smooth downstream reactions. Our technicians see the subtle changes in melting point or color as clues—when a batch is off-spec, they find out why, drawing on years of hands-on troubleshooting.

    Understanding the Heart of Purity and Performance

    Working with raw phenols always comes down to how clean you can get your output. The melting point for high-purity 3,4-xylenol generally approaches 62-64°C, with purity drifting above 99%. These aren't just numbers for the spec sheet. These values let downstream chemists predict reactivity and get repeatable performance—no guessing on side reactions, no waste of catalyst, no hidden surprises. It doesn’t matter whether our customers synthesize specialty resins or formulate crop protection products; undesirable isomers wreck efficiencies and can turn a winning process into a headache.

    Day in and day out, our staff checks each lot for water and heavy metal content. Even trace iron or copper, introduced by worn pumps or valves, can compromise color stability of derivatives made from xylenol. On processing lines, we invest in corrosion-resistant steel and real-time analytical tools, since cutting those corners leads to more than just a failed test—it causes headaches months down the supply chain. Our plant teams understand that by removing these impurities at the start, the rest of their supply chain runs smoother, and incidents down the road drop. Fewer batch failures, fewer product recalls, less long-term risk to brand value.

    3,4-Xylenol in Action: Onsite Stories and Best Practices

    Every seasoned production supervisor in our factory has stories about the ripple effects of one batch of off-purity xylenol. Maybe a 3,5-isomer creeped in, or the moisture content spiked after a humid week and inadequate storage. For soap and disinfectant producers, these minor changes in feedstock can show up as product haze, instability, or even odors that throw off the end-user. In resin synthesis, controlling the ratio of isomers prevents unwanted cross-linking; the right feed cuts the chances of downstream process upsets during high-temperature curing. The lesson is clear after years of output: reliable chemistry flows from rigorous control upstream.

    Our experts have also seen major differences in how customers use 3,4-xylenol compared to other isomeric phenols. For example, 2,4-xylenol may be more abundant on the global market due to different separation efficiencies, but it brings distinct reactivity patterns. Customers making advanced phenolic resins or biocidal formulas have told our application team that if the wrong isomer sneaks in, the product performance drifts—and not in a good way. Simple switches can cause foam problems in liquid cleaners, or incomplete polymerization. There’s a reason discerning users stick to 3,4-xylenol despite sometimes higher cost or additional lead time: it just works better for certain chemical transformations, and the differences show up in profit and reliability.

    How Model and Specification Choices Affect Production

    Our factory doesn't view 3,4-xylenol as a generic, one-size-fits-all supply. Depending on the intended use, distinct grades are requested by our buyers. Industrial grade material may calm concerns about trace solvents or intermediate color, as long as the xylenol does its job in non-critical applications. Pharmaceutical or fine chemical clients, by contrast, expect documentation tracing every batch back to the raw feed, with gas chromatography and moisture readings below 0.1%. This tracking reassures downstream partners that off-spec plant batches will never shadow them.

    Internally, our QC records hold years of physical data—melting range, color index, moisture levels, and impurity profiles. Each shipment matches these benchmarks, and in unusual weather, our plant managers know to run extra drying steps or retest before drumming. We learned over time that model and specification requirements do not just keep contracts in-line between seller and buyer. They help keep entire product lines on course—from a factory in China to a resin plant in California, the numbers in your COA (certificate of analysis) make or break a relationship with your customer. Nobody at our plant risks that trust for a quick shortcut. When a buyer calls us about a slight impurity, they talk directly to the lab that made that batch, not to someone in a call center. Hands-on chemical manufacturing always answers for the product it sells.

    Safety, Handling, and Hard-Earned Lessons

    Our crews have handled 3,4-xylenol long enough to understand the difference between reading a SDS and actually staying safe on the job. It’s not enough to say “use PPE” or “store in a cool, dry place.” At scale, chemical compatibility, ventilation, and spill management all matter. We’ve learned that xylenols, especially when stored warm or exposed to moisture, can lead to caking and discoloration over even a few days if conditions are off. Regular drum rotation, desiccant use in storage, fast turnover schedules—these are simple but hard-learned disciplines in our warehouse.

    There isn’t much tolerance in modern industry for incident-driven management. Our safety officers track every handling error, no matter how small, using records stretching back decades. If a valve seizes or a gasket fails, it gets replaced that shift—downtime beats a spill every time. This commitment gives our downstream partners peace of mind, since they know their production won’t be thrown by careless chemical transfer or off-gassing in transit. Every safe batch comes from a factory where safety is routine, and trace records aren’t just for show.

    The Distinct Benefits of Our 3,4-Xylenol Compared to Other Phenolic Intermediates

    For process chemists and purchasing managers, the temptation to treat all phenolic intermediates as interchangeable can cause bottlenecks. From first-hand conversations with our regular buyers, we know most are looking for particular performance traits: melting behavior, color stability, and predictable reactivity. The key differences between 3,4-xylenol and its siblings lie in reaction selectivity and downstream versatility.

    Here’s a case from our resin clients: 3,4-xylenol delivers more uniform polymer branches and higher yield in modified phenolic resin systems, compared to 2,6-xylenol or mixed isomer cuts. Control over curing time—important for coating strength and appearance—tightens up, so QC passes more batches without rework. Our own technical staff tested competitive lots from several regions, and we saw variances of up to 10% in side product formation depending on source and purification method. This isn’t just trivia: one customer running a continuous phenol-formaldehyde line swapped suppliers in a pinch and paid by wasting a third of their catalyst stocks. Our choice to keep strictly to purified 3,4-xylenol has helped long-term buyers avoid these hidden costs.

    Another difference appears in biocidal and disinfectant blends. The potency and longevity of certain preservatives draw on the precise substitution pattern found in 3,4-xylenol. We’ve entered multiple field trials with industry partners, finding that even slight contamination with other xylenol isomers can shift the active spectrum or shorten shelf life. Nobody likes to recall a whole run of product because a main input decayed days before promised shelf stability. This is where we see end users sticking with our tightly controlled batches—even in cutthroat price markets—because the chemistry and real-world performance agree.

    Lessons Learned from Years on the Production Floor

    There’s nothing abstract about the challenges faced by chemical producers. Each batch tells its own story: how raw materials responded to upstream purification, how pumps ran on extra-humid days, what happened after a minor change in filtration protocol. Our approach to 3,4-xylenol supply keeps evolving. Years ago, an upstream supplier sent in a batch with trace sulfur contamination—a near-miss we caught because our staff knows the yellowish coloration that sneaks into the solution. Washed and rechecked, the material never made it to a customer.

    This dedication to detail doesn’t just shield us from recalls. Our regular dialogue with large and small downstream buyers lets us update methods to meet shifting regulatory limits or keep up with new market demands. Major users in electronics chemicals urged us to reduce water and trace organic solvents further; we invested in in-line moisture analyzers that flag deviations the moment they arise, not days later. Agricultural chemical buyers ask for rapid packaging and turnover, so our logistics team keeps inventory moving, not sitting.

    A plant manager who started as an operator still walks the line, remembering tight deadlines and production snags. New staff shadow experienced techs for weeks before operating a reactor solo. It’s not just about reading gauges; hands-on care and decades of collective know-how keep standards high. Our culture passes this knowledge on, so every batch reflects hard-won lessons and shared responsibility.

    Troubleshooting, Customer Support, and the Realities of Chemical Supply

    After years in this business, we’ve learned that open, technical conversations keep customers coming back. If an end user flags even a minor shift in their production results, our technical support crew gets right into the plant records and analytical data. We don’t just ship material and vanish—we track performance trends, help troubleshoot where things change, and sometimes even tweak our purification steps to solve an issue. In one instance, a resin manufacturer flagged a small change in polymer clarity traced to a subtle bump in our chlorinated byproduct trace. Our team isolated the source, adjusted our post-reactor wash, and saw immediate improvement the next batch. This kind of agility sets apart true manufacturers from trading houses, and people see the difference in real costs and reliability.

    The feedback loop between our operation and the customer floor runs both ways. Our field reps gather honest feedback and challenge our lab staff to solve practical problems—not abstract purity goals, but real-world challenges like resin gelling, phase separation, or storage caking. When a new regulation emerges, we field the requests right at the manufacturing line, not months later through a chain of intermediaries. Our reputation lives and dies by these fast, knowledgeable responses.

    In every case, transparency forms the backbone of these relationships. Customers see real data, accurate to the lot, with explanations that make sense. We own every shipment—good or bad. No passing the buck. This is how trust gets built and why many of our buyers have stuck with us for decades.

    Enabling Sustainable Processes with 3,4-Xylenol

    Sustainability has turned from a buzzword into a daily grind at our plant. Over the last decade, we’ve faced mounting pressure to cut hazardous waste, minimize solvent use, and lower energy draws. Not every step is glamorous or headline-worthy. In practice, this means optimizing methylation efficiency so fewer unwanted byproducts end up as waste. Solvent recovery systems—expensive and sometimes temperamental—let us recycle most of our process fluids, slashing both cost and emissions.

    Our production engineers also focus on responsible water use. At commercial scale, demisting, cooling, and washing eat through thousands of liters weekly. By tracking water quality metrics and investing in closed-loop rinse systems, our water use per ton dropped by a factor of two in just five years. This isn’t just good for compliance; it keeps us competitive as utilities hike rates or new environmental rules come in.

    Every improvement makes our 3,4-xylenol a lower-impact option for downstream products. Some of our multinational customers now require supply chain disclosures on energy and water use, plus traceability for key intermediates. Our ability to meet and document these requirements comes from steady, incremental improvements across the facility. Responsible production isn’t an isolated project; it’s woven into every measurement and every operator shift log.

    Looking Ahead: Adapting Production for Future Demands

    Chemical manufacturing never stands still. Global demand for high-quality 3,4-xylenol keeps rising as more specialty applications emerge and regulatory pressure tightens. Each market shift brings new requirements, and our teams pivot to meet them—not by shortcut, but by continuous improvement and troubleshooting. We’ve survived downturns, raw material squeezes, and regulatory overhauls by anchoring our business in technical expertise and practical flexibility.

    Our regular process reviews, open communication with customers, and willingness to invest in plant upgrades not only protect our margins—they keep our operation aligned with the next wave of challenges, whether it’s a new application or a tighter impurity profile. As new uses for phenolic intermediates develop, we draw on the wisdom built through years of day-to-day work. Every buyer, whether working in a legacy chemical plant or a cutting-edge materials startup, relies on this combination of know-how and adaptability.

    What distinguishes us as a direct manufacturer always circles back to hands-on experience and proven delivery. We’re not just supplying a commodity—we’re building a partnership where both sides understand the risks, rewards, and realities of producing top-grade 3,4-xylenol. The names and faces may change, but the results and commitment stay the same.

    Putting 3,4-Xylenol to Work Today and Tomorrow

    To sum up what we bring to the table: the journey of 3,4-xylenol in our plant doesn’t end in a drum leaving the warehouse. It shows up in every downstream innovation enabled, every prevented recall, every confident purchase order that keeps supply chains running. Reliable, well-documented batches are born from real-world experience and a refusal to settle for shortcuts. As production challenges shift, our approach to 3,4-xylenol evolves to meet new expectations. Partnering with a hands-on maker, not just a box-mover, puts stable, responsible chemistry within reach for all stakeholders.