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3,4-Dichlorotoluene

    • Product Name 3,4-Dichlorotoluene
    • Alias 1,2-Dichloro-4-methylbenzene
    • Einecs 210-118-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    689678

    ChemicalName 3,4-Dichlorotoluene
    CASNumber 95-49-8
    MolecularFormula C7H6Cl2
    MolecularWeight 161.03 g/mol
    Appearance Colorless to pale yellow liquid
    BoilingPoint 208-211 °C
    MeltingPoint -11 °C
    Density 1.27 g/cm3 at 25 °C
    RefractiveIndex 1.553 at 20 °C
    FlashPoint 85 °C (closed cup)
    Solubility Insoluble in water, soluble in organic solvents

    As an accredited 3,4-Dichlorotoluene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1-liter amber glass bottle with a tight-sealed cap, labeled "3,4-Dichlorotoluene," hazard symbols, and handling instructions clearly displayed.
    Shipping 3,4-Dichlorotoluene is shipped in tightly sealed containers to prevent leaks and evaporation. It should be stored in a cool, well-ventilated area, away from heat and ignition sources. During transport, it must meet applicable hazardous materials regulations, ensuring proper labeling, secure packaging, and appropriate documentation to guarantee safe and compliant handling.
    Storage 3,4-Dichlorotoluene should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from direct sunlight, heat sources, and incompatible materials such as strong oxidizers. Ensure containers are clearly labeled and protected from physical damage. Access should be restricted to trained personnel. Store at room temperature and avoid exposure to moisture to prevent degradation or hazardous reactions.
    Application of 3,4-Dichlorotoluene

    Applications of 3,4-Dichlorotoluene in Industrial Manufacturing

    3,4-Dichlorotoluene is an essential intermediate widely adopted by downstream manufacturers as a chlorinated aromatic compound in various chemical synthesis workflows. Our material consistently meets the strict quality and purity standards required for direct incorporation into advanced formulations. Below, we outline several distinct end-use manufacturing sectors where 3,4-Dichlorotoluene plays a critical role, detailing compliance requirements, recommended formulation ratios, industrial process integration points, and the types of final products produced.

    1. Agrochemical Active Ingredient Synthesis

    Major crop protection product manufacturers use 3,4-Dichlorotoluene as a key building block for the synthesis of selective herbicides and fungicides, especially where targeted chlorinated benzene derivatives are essential for biological activity. The compound's controlled reactivity and reliable availability enable precise coupling reactions and functionalization steps during active ingredient preparation, ensuring batch consistency from pilot to commercial scale.

    Industry compliance standards

    • FAO/WHO Technical Specifications for Pesticides (FAO, WHO)
    • EU Regulation (EC) No. 1107/2009 on Plant Protection Products
    • ISO 9001:2015 certified quality management for batch traceability
    • REACH Registration (EC 1907/2006)

    Typical usage ratio

    • Usually 8–15% by mass as a core intermediate substrate; adjusted according to target molecule yield and side-chain functionalization requirements.

    Downstream process integration

    • Introduced during initial aryl chlorination and subsequent coupling steps, commonly via Friedel-Crafts alkylation or selective substitution in the early stages of agrochemical active molecule assembly.

    Final product types

    • Selective pre- and post-emergence herbicides (e.g., chlorinated anilides, triazines)
    • Systemic fungicides derived from dichlorotolyl moieties
    • Intermediates for insecticidal agents

    2. Pharmaceutical Intermediate Manufacturing

    The pharmaceutical sector employs 3,4-Dichlorotoluene for the preparation of advanced intermediates during the synthesis of specific APIs, notably those requiring ortho/para dichloro substitution on the aromatic ring for selectivity, pharmacokinetic modulation, or patent-defined molecular architecture. Automated process control ensures purity at all synthetic stages, supporting the production of pharmaceutical-grade materials in regulated environments.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • European Pharmacopoeia and US Pharmacopeia residual solvent and impurity limits
    • 21 CFR Part 211 (FDA cGMP for finished pharmaceuticals)
    • GMP facility certification for process intermediates

    Typical usage ratio

    • Ranges from 5–10% weight as a precursor, precisely optimized based on the molecular route for each pharmaceutical target.

    Downstream process integration

    • Feeds directly into Grignard reactions, aromatic amination, or oxidative functional group conversion steps; reacts under controlled temperatures and atmospheric conditions to limit by-products and achieve repeatable intermediate quality.

    Final product types

    • Chlorinated pharmaceutical intermediates for antipsychotic drugs
    • API side-chain building blocks for cardiovascular and CNS medications
    • Reference standards for method validation

    3. Dye and Pigment Precursor Production

    Manufacturers of high-performance dyes and specialty pigments rely on 3,4-Dichlorotoluene for its utility in generating custom chlorinated aromatic substrates. The material enters the supply chain for diazo and azo dye intermediates, providing color fastness and light stability features necessary for automotive, textile, and coatings applications. Quality assurance teams monitor isomeric purity and residual halogens to ensure compliance with downstream performance targets.

    Industry compliance standards

    • OEKO-TEX® Standard 100 compliance (textile sector)
    • EN 71-3:2019 Safety of Toys—Migration of Certain Elements
    • ISO 14001:2015 Environmental Management for chemical processing
    • European BAT (Best Available Techniques) Reference Documents for pigment and dye manufacture

    Typical usage ratio

    • As high as 12–20% by total batch mass, depending on the chromophore structure and additional halogenation reactions intended.

    Downstream process integration

    • Engaged in the initial halogenated aromatic feedstock charge, often followed by sulfonation, nitration, or amination steps to introduce azo linkages or extended π-systems required for application-specific pigmentation.

    Final product types

    • Reactive and disperse dyes for synthetic and natural fiber coloration
    • Specialty organic pigments for automotive and industrial coatings
    • Colorants for inkjet and laser printing technologies

    4. Specialty Monomer and Polymer Synthesis

    In the advanced materials sector, 3,4-Dichlorotoluene serves as a controlled functional unit for synthesizing fluorinated and chlorinated specialty monomers. These feedstocks enter copolymerization sequences where tailored halogen content imparts unique thermal, flame-retardant, and chemical resistance properties to finished polymers demanded in electronics, construction, and wire insulation industries.

    Industry compliance standards

    • UL 94 Flammability Standard for Plastic Materials
    • RoHS Directive (EU) 2011/65/EU for restricted substances
    • ASTM D638 for polymer tensile property characterization
    • ISO 9001:2015 process control for consistent monomer supply

    Typical usage ratio

    • Typically 3–8% in copolymerization feeds, adjusted based on polymer target specification and desired halogen incorporation per repeat unit.

    Downstream process integration

    • Charged during monomer synthesis, followed by catalytic coupling or Friedel-Crafts alkylation to generate the target polymerizable unit, then introduced to bulk or solution polymerization reactors.

    Final product types

    • Chlorinated engineering plastics for electronic housings
    • High-performance films and insulation coatings for cables
    • Specialty resins for composites and corrosion-resistant linings

    5. Fine Chemical Custom Synthesis

    Contract and custom fine chemical companies select 3,4-Dichlorotoluene as a starting material for multistep syntheses, especially for constructing rare chlorinated aromatics that serve as proprietary molecular scaffolds in research reagents, advanced analytical standards, and high-purity calibration compounds. Stringent process documentation and analytical method validation are maintained at all steps to comply with customer and regulatory requirements.

    Industry compliance standards

    • ISO 17034:2016 for reference material producers
    • Good Laboratory Practice (GLP) guidelines (OECD, EPA)
    • ISO 9001:2015 certified traceability for every synthesis lot
    • REACH registration and notification for research applications

    Typical usage ratio

    • Between 1–5% in multi-gram to kilo-lab scale syntheses, chosen according to target compound structure and stepwise yield optimization.

    Downstream process integration

    • Introduced in initial step as the stable aromatic starting point for halogen exchange, followed by custom arylation, nitration, or derivatization reactions as per customer specification.

    Final product types

    • Analytical grade chlorinated aromatic standards
    • Building blocks for research molecule libraries
    • Synthons for advanced computational chemistry and spectroscopic validation
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    Certification & Compliance
    More Introduction

    Introducing 3,4-Dichlorotoluene: Practical Insights from the Chemical Manufacturer

    Real-World Use and Experience with 3,4-Dichlorotoluene

    The chemical industry constantly grows in complexity, and effective building blocks make a big difference. On the production line, 3,4-dichlorotoluene stands out for its steady performance and the critical role it plays in multiple downstream applications. Chemists in our facility pay close attention to the fine details that distinguish this compound from the crowd. Experience has taught us that a reliable supply of 3,4-dichlorotoluene often determines the pace and success of projects from agrochemicals to specialty polymers.

    Our operations focus on 3,4-dichlorotoluene with a purity exceeding 99.5%—a threshold set not for marketing appeal but because lower grades tend to cause unpredictable outcomes in demanding syntheses. With a molecular formula of C7H6Cl2, 3,4-dichlorotoluene distinguishes itself by its two chlorine atoms at the meta and para positions. This exact substitution pattern creates unique reactivity that is hard to mimic with related compounds such as 2,4- or 2,6-dichlorotoluene. From batch to batch, we regularly analyze our product by GC-MS and FTIR so chemists using our material get consistent results. Over the years, our own process engineers have learned to spot the impurities that often slip past the untrained eye, and by reducing these, the finished chemical performs better in further reactions—especially halogen exchange and acylation steps.

    Meeting Application Challenges in the Field

    3,4-Dichlorotoluene supports a surprising range of industrial and specialty uses. Synthetic dye manufacturers rely on the stable halogen positions for reliable intermediate formation, and custom polymer producers appreciate how these same features steer molecular branching in their resins. It takes years of real-world experience to pick up on the subtle differences between isomers in downstream processing. For example, agricultural firms developing next-generation herbicides find the meta-para arrangement in 3,4-dichlorotoluene especially beneficial; certain target molecules call for this exact structure to introduce further substitutions without tedious and expensive protection-deprotection steps.

    Not all dichlorotoluenes perform alike. Lab-scale tests demonstrated that isomers with ortho substitution often run into steric hindrance, and reactions intended for the 3,4-isomer simply fail with 2,4- or 2,6-dichlorotoluene. Factories committed to continuous improvement notice fewer waste streams and rework batches when sticking to the 3,4 variant for sensitive syntheses. Analytical feedback from several longtime customers confirms that our version yields higher overall recovery rates due to the tighter boiling range and reduced tar fractions in distillation.

    Technical Considerations: Specifications and Handling

    In real manufacturing environments, ease of handling counts. Workers appreciate that our 3,4-dichlorotoluene shows low viscosity and a manageable odor profile, which means safer loading and minimal downtime for air filtration maintenance. With a boiling point around 211 °C and a melting point well below room temperature, it stays liquid in typical plant conditions, removing headaches about solidification in drums or transfer lines. Our facility stores this material under nitrogen to limit oxidation, drawing on lessons learned during summer humidity spikes, as trace hydrolysis or light exposure can introduce off-spec upshots—hard-earned insight from previous production runs.

    Most fields using 3,4-dichlorotoluene, whether large multinationals or focused process shops, value technical steadiness over mere availability. Our analytical chemists frequently check chlorine content and toluene impurities because these often trip up downstream catalysts or poison reaction media. During plant trials, we noticed that even minor contamination with monochlorotoluene can undercut the desired reactivity in cross-coupling steps, so our plant team runs an extra purification pass during campaign production. Over decades, what looks like an extra cost up front proves economical once time and waste savings are tallied.

    On the logistics side, repackaging for long-distance shipment requires care. In our experience, special attention to moisture control during filling and transportation really pays off for customers manufacturing pharmaceutical intermediates. Rust formation in bulk containers can alter trace metal content, a small detail that means a lot for those with strict regulatory hurdles. We use lined drums and regular container inspections, avoiding the false economy of bare steel under humid conditions. Our technical staff keeps an open line for all client feedback, recognizing that practical input is more valuable than a simple specification sheet.

    Real Differences Compared to Other Chlorotoluenes

    Chemists and engineers on our staff receive plenty of questions about whether one isomer can substitute for another in a pinch. Textbooks provide general guidance, but decades of experience show that real-world results often tell another story. Products such as 2,4-dichlorotoluene and 2,6-dichlorotoluene share the same formula, but reaction profiles and solvent compatibility do not overlap as much as theory suggests. During extension research, we observed cleaner product streams using 3,4-dichlorotoluene in nucleophilic aromatic substitution and oxidative coupling, while its isomeric counterparts tended to generate byproducts requiring time-consuming purification. This cleaner operation also reduces need for excessive solvent washes, supporting both plant efficiency and sustainability goals directly.

    Researchers developing new fine chemicals point out that steric and electronic effects in 3,4-dichlorotoluene open routes impossible or impractical with other isomers. Feedback from our partners highlights superior yields in specific pharmaceutical syntheses, where substitution at defined ring positions controls bioactivity and minimizes off-target effects. As producers, we monitor these end-use results closely, studying returns and customer reports, then use this data to tune our reactors, catalysts, and workup sequences. This focus results in fewer recalls or post-delivery adjustments, saving both us and our partners from costly downtime.

    Supporting Safe and Reliable Use: Lessons from the Plant Floor

    Daily handling shapes our perspective far more than literature ever could. Employees at our site receive focused safety training, with direct attention to containment during filling and draining. Chlorinated aromatics can cause headaches if handled carelessly, so our success comes from a commitment to minimizing exposure and maintaining a tidy shop. Regular air monitoring and leak checks go beyond compliance—these habits prevent workplace issues and keep production on schedule. Over years of operation, these measures led to lower staff turnover and a stronger safety record—an advantage rarely seen in statistics, but clear in morale and output.

    Waste management also matters. Our plant converts off-spec streams into lower tier products, using managed recovery processes. By reclaiming usable material, we've driven down costs and shrunk waste output. In operations, the mantra becomes clear: every kilogram wasted is a kilogram too many for both profit and environmental stewardship. Policy changes may push sustainable processes, but it is those on the shop floor who innovate to reclaim and refine streams once treated as disposable.

    From Raw Material to Finished Goods—A Manufacturer's View

    Experience reveals that customers want more than a raw chemical. We listen carefully when formulators highlight sensitivity to certain byproducts, or when their reactors display quirks around trace impurities. Lead chemists on our staff take this feedback and work backwards, improving steps in our chlorination and purification, sometimes adjusting feedstock suppliers or reactor residence times to hit tighter purity goals.

    Established buyers notice when batches flow well and perform reliably, which comes down to small choices made every day in the plant. We track shelf life by monitoring color, acidity, and impurity levels over months, not weeks. Problems like yellowing—a sign of breakdown or air ingress—prompt immediate root-cause review, not a shrug and a discounted offer. Being a manufacturer, we don’t have the luxury of cutting corners; the cost always resurfaces somewhere else down the line.

    Our teams find that industries aiming for scale—whether water treatment, coatings, or crop protection—prefer a partner willing to troubleshoot with them, not just supply to order. Plant engineers often open up about the hurdles met during pilot scale-up, and we respond by sharing our own process knowledge. Often, tweaks in feed temperature or solvent use can make a huge difference in reactivity, so we keep lines of discussion open all the way from lab concept to filling tanker trucks.

    Facing Future Demands: Adapting for Quality, Compliance, and Growth

    New regulatory expectations continue to shape chemical manufacturing. Rules around emissions and trace impurity disclosure always seem to catch changing winds, and each shift means re-examining not just paperwork, but real plant conditions. Frequent audits and process reviews ensure that our 3,4-dichlorotoluene keeps pace with these changes. Our quality team stays updated on European REACH, U.S. TSCA, and APAC directives, not out of obligation but because we know that trusted supply depends on awareness, not surprise.

    In some regions, buyers place stricter requirements on residual heavy metals or banned solvents—a detail only obvious to those who’ve navigated real export challenges. Our track record shows that close relationships with accredited external labs, unannounced sample draws, and honest reporting make compliance a shared goal instead of a burden. Several times, early detection via our GC-MS routines allowed us to fix a potential compliance snag before a customer ever noticed. Lessons like these push us to keep raising our own standards.

    Anticipating Industry Trends and Customer Needs

    Global markets push manufacturers to adapt. End users increasingly ask about sustainability, lifecycle impacts, and future supply risks. We hear these concerns frequently, so we reduced our reliance on water-intensive post-chlorination washes and invested in solvent recycling systems. Collaborating across the value chain, we now capture both energy and ingredients once lost in vent systems or discarded as spent catalysts. Larger buyers appreciate these efforts, pointing to sustainability report requirements and shareholder expectations. Even smaller shops—when processing niche pharmaceuticals—value the clear audit trails we maintain. It reflects not just compliance, but a mutual respect built on transparency.

    Traditionally, advances in process chemistry came from academic labs and then scaled up. Our staff takes a different approach, drawing from hands-on learning in live production settings. Practical chemistry reveals unexpected pitfalls or opportunities, and we rapidly transfer insights from one line to another. Sometimes process upgrades—like in-situ purification or automated vent balancing—develop after a late-night troubleshooting call, not in a published paper. This practical wisdom guides our continuous improvement far better than any isolated R&D plan.

    As the downstream world evolves, we help customers balance performance, cost, and complexity. In the last five years, we’ve seen more multi-step syntheses request tighter impurity control and higher reaction consistency. Our response draws directly on plant experience and long-term testing. As our feedstocks shift and market availability fluctuates, we maintain steady quality through careful inventory control and backup supply contracts. This gives both us and our customers a cushion during supply chain shocks—something theory can't always predict.

    Community, Collaboration, and Lasting Value

    Manufacturing high-value chemicals like 3,4-dichlorotoluene relies on more than equipment and recipes. It becomes a community effort, where plant operators, analytical chemists, engineers, and end users all share a stake. We’ve learned that open lines of communication build real trust. Early notification of production issues allows partners to plan alternate runs or adjust logistics. Shared project reviews sharpen everyone’s expertise and reduce costly misunderstandings.

    This spirit of collaboration extends into problem solving. When a customer flags an unexpected reduction in yield, our team dives in with fresh samples, root-cause analysis, and data from our control chart archives. Together, we sort out whether the issue stems from material, method, or machinery, always taking responsibility for our own piece of the puzzle. In several instances, our early troubleshooting tips helped avoid shutdowns or recall headaches, which pays off in hard-won loyalty.

    Our commitment means taking feedback seriously, good or bad. We make it a point to send technical staff, not just sales representatives, to customer visits. This philosophy has led to product improvements and higher reliability throughout the chain, a benefit that shows in strong, repeat relationships rather than occasional spot sales.

    What All This Means for You

    As a manufacturer with deep roots in chemical production, our perspective centers on how choices in process, purity, and service lead to better outcomes for all parties—whether raw materials end up in high-stakes crop protection, demanding electronics, or advanced specialty materials. Working daily with 3,4-dichlorotoluene sharpens our focus on real usefulness, not just theoretical advantages. By paying close attention to the construction of our own product and its downstream impact, we help partners build success into every batch.

    The lessons drawn from real manufacturing experience—attention to input quality, investment in plant and people, and a spirit of shared improvement—combine to make a stronger offering. Buyers who demand performance, safety, and reliability find value in our 3,4-dichlorotoluene not because of a marketing plan, but because of the teamwork, careful listening, and technical knowhow that goes into every delivery.