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3,4-Dichlorophenol

    • Product Name 3,4-Dichlorophenol
    • Alias 3,4-DCP
    • Einecs 203-405-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    921010

    CAS_Number 95-77-2
    Molecular_Formula C6H4Cl2O
    Molar_Mass 163.00 g/mol
    Appearance Colorless to pale yellow solid
    Melting_Point 52-56°C
    Boiling_Point 210°C
    Density 1.5 g/cm³
    Solubility_in_Water 0.5 g/L (at 20°C)
    Vapor_Pressure 0.17 mmHg (at 25°C)
    Flash_Point 92°C
    Odor Phenolic
    pKa 8.03
    LogP 3.06

    As an accredited 3,4-Dichlorophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500g amber glass bottle labeled "3,4-Dichlorophenol," features hazard symbols, chemical details, manufacturer info, and tightly sealed cap.
    Shipping 3,4-Dichlorophenol should be shipped as a hazardous chemical in accordance with relevant regulations (e.g., DOT, IATA, IMDG). Use suitable, tightly sealed containers, label clearly, and package to prevent leaks. Store and ship away from incompatible substances, and ensure proper documentation and Safety Data Sheet (SDS) accompany the shipment.
    Storage 3,4-Dichlorophenol should be stored in a tightly closed container in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizing agents and bases. Keep away from heat and sources of ignition. Store away from direct sunlight. Clearly label the container and ensure secondary containment to prevent spills or leaks. Use corrosion-resistant shelves if possible.
    Application of 3,4-Dichlorophenol

    Applications of 3,4-Dichlorophenol in Industrial Manufacturing

    3,4-Dichlorophenol serves core functions as a chemical intermediate in multiple sectors. As direct manufacturer, we ensure tailored integration, downstream purity, and consistent batch traceability for value-added industrial workflows.

    1. Agrochemical Synthesis Intermediates

    This material is primarily used to manufacture specific herbicides and fungicides. Our clients employ it in multi-step syntheses, where its dichloro-substitution pattern supports targeted halogenation and subsequent functional group incorporation. Key products include phenoxy acids and complex heterocyclic agrochemicals made via chlorinated coupling reactions. Compliance with export controls and safe handling systems are mandatory throughout the process.

    Industry compliance standards

    • REACH (EU Regulation No 1907/2006), registration and use restrictions for precursors
    • US EPA Pesticide Registration and Manufacturing Quality Control Standards (40 CFR Part 158)
    • China National Standard GB 20784 for Pesticide Intermediates
    • ISO 9001 certified QC protocols for traceability

    Typical usage ratio

    • Intermediate batches: 0.8–1.3 molar equivalents relative to final active compound; precise proportion adjusted according to desired substitution yields and target molecule framework.

    Downstream process integration

    • Batchwise introduction during phenol halogenation or ether synthesis stage
    • In/at coupling with carboxylic acids or aromatic amines for active ingredient formation
    • Purification by distillation or crystallization for active isomer isolation

    Final product types

    • Herbicides (e.g., dichlorophenoxyacetates)
    • Systemic fungicides
    • Soil treatment chemicals

    2. Pharmaceutical Intermediate for Active Ingredient Synthesis

    Pharmaceutical manufacturers utilize 3,4-Dichlorophenol for synthesizing several APIs, notably within anti-infective and anti-inflammatory compound families. Its application primarily lies in aryl halide reactions, offering reliable precursor quality for stringent medicinal chemistry. Each batch undergoes validated source verification and meets internationally harmonized impurity specifications for drug synthesis.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredient Manufacturing
    • USP-NF/BP reference monograph for intermediates
    • FDA cGMP (21 CFR Part 210/211) for pharmaceutical ingredient supply
    • EDQM CEP standards on traceability

    Typical usage ratio

    • Usually 0.75–1.1 equivalents relative to precursor aryl components. Adjusted according to specific molecule pathway and target impurity profile during stepwise synthesis.

    Downstream process integration

    • Reacts during aromatic substitution to introduce dichloro moiety within the API molecular backbone
    • Integrated into multistage synthesis of phenolic pharmaceuticals
    • Subjected to purification prior to kinase inhibitor or non-steroid anti-inflammatory agent synthesis

    Final product types

    • Antimicrobial APIs
    • Intermediate for analgesics
    • Precursors to anti-inflammatory drugs

    3. Dye and Pigment Production

    Industrial colorant factories use dichlorophenol as a key precursor in synthesizing specialty azo and phthalein dyes. Its electronic structure facilitates coupling reactions giving specific chromatic properties, particularly in the yellow, orange, and brown color spectrum. End-users require tight control of chlorine content and isomeric purity for high-stability pigment batches used in plastics, inks, and coatings.

    Industry compliance standards

    • EN 71-3 (Safety of Toys – migration of pigment chemicals)
    • ISO 9001 for colorant manufacturing traceability
    • Restricted Substances List (GADSL) compliance for automotive applications
    • ASTM D5398 for pigment purity and composition

    Typical usage ratio

    • Colorant reaction: 0.6–1.0 equivalents based on target color intensity and shade; precise dosage set by intended pigment chemical structure.

    Downstream process integration

    • Dosed during initial diazotization and coupling phase of dye synthesis
    • Used in Friedel–Crafts alkylation steps for pigment manufacture
    • Incorporated before pigment dispersion or granulation

    Final product types

    • Azo dyes for textiles and inks
    • Phthalein pigments for plastics compounding
    • Coating colorants with enhanced UV resistance

    4. Synthesis of Polymer Additives and Stabilizers

    Manufacturers of specialty plastics introduce dichlorophenol as a precursor for antioxidant and UV absorber additive production. Structural features of this phenolic allow formation of high-stability stabilizers, protecting polymer chains in high-temperature or high-exposure applications. QC requires sub-500ppm trace halides and full organics screening for downstream compounding compatibility.

    Industry compliance standards

    • EU Regulation (EC) No 10/2011 for food-contact plastics components
    • RoHS Directive (2011/65/EU) for restricted substance content
    • ISO 14001 Environmental Management for manufacturing footprint
    • ASTM D6280 for plastics additives

    Typical usage ratio

    • 0.1–0.25 wt% in additive synthesis before blending into polymer matrix; level varies by polymer type and final application environment stress.

    Downstream process integration

    • Introduced before condensation polymerization or additive esterification
    • Processed in batch reactors for stabilized phenolic antioxidant formation
    • Blended post-reaction into masterbatch for film, fiber, or molded part production

    Final product types

    • Phenolic antioxidants for polyethylene and polypropylene
    • UV absorber masterbatches for outdoor-use polymers
    • Stabilizing agents in PVC and other thermoplastics

    5. Wood Preservative Formulations

    Timber treatment plants incorporate dichlorinated phenols in formulations for both preventive and remedial wood protection. The compound acts as a precursor for synthesizing formulations against fungal decay and insect attack. Quality oversight addresses in-situ transformation products and ensures residual chemical remains below mandated migration limits for construction and outdoor exposure materials.

    Industry compliance standards

    • EN 599-1 (Efficacy of wood preservatives, EU Biocidal Product Regulation BPR)
    • US EPA 40 CFR 152 for wood preservation active substances
    • ISO 22196 for effect on surface antifungal performance
    • China GB 18580 for wood products and hazardous substance limits

    Typical usage ratio

    • Applies at 0.2–0.6 wt% in concentrated wood treatment solutions before dilution and impregnation. Dosage strictly adapted per timber species and end-use category (structural, exterior, marine).

    Downstream process integration

    • Synthesized as a biocidal intermediate before onsite dilution into waterborne or solvent-based preservative blends
    • Impregnated by vacuum-pressure method into wood substrates
    • Post-treatment monitoring for leachables and chemical stability

    Final product types

    • Indoor and outdoor pressure-treated timber
    • Fence and decking materials
    • Industrial wooden pallets and packaging
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    Certification & Compliance
    More Introduction

    3,4-Dichlorophenol: Quality from the Manufacturer’s Perspective

    Understanding Our Commitment to Pure 3,4-Dichlorophenol

    As a chemical manufacturer with long-standing expertise in chlorinated aromatic compounds, we have seen expectations for product consistency and safety climb sharply. Among the lineup, 3,4-Dichlorophenol (CAS No. 95-77-2, C6H4Cl2O) draws particular attention in both specialty chemical synthesis and industrial processing. Chemists and downstream buyers rely on us to deliver a compound that meets rigorous standards while addressing needs that go beyond the specification sheet. Drawing insight from years running commercial-scale reactors, we understand not just the chemical but the practicality of using 3,4-Dichlorophenol across industries—from downstream fine chemical synthesis to active ingredient development.

    Consistent Production, Reliable Quality

    Our typical batch sizes remain flexible, ranging from pilot runs for research customers to full-scale drums for major buyers. The physical form stands out— customers receive a fine, white to tan crystalline solid, free of foreign particulates and unwanted color impurities. We prioritize minimal trace hydroquinone, monochlorophenols or organic solvents in the finished material. Using hydrochloric acid catalysis, chlorination, and distillation, our process technology trims nominal content of related isomers to distinctly low levels.

    In the lab, chemists look for easy solubility in organic solvents, low melting point range (approximately 68 to 71°C), and prompt reactivity toward nucleophilic aromatic substitution. Production teams regularly check purity by GC and HPLC analysis, targeting at least 99% content by weight. During years of routine scaling, we have optimized filtering and drying steps. This yields product that remains free-flowing in storage without suffering from caking or clumping, simplifying handling for anyone using both manual and automated dosing systems.

    From Synthesis to End-Use—In the Trenches

    Years in the manufacturing trenches have shaped how we view 3,4-Dichlorophenol’s role. A major application is as an intermediate for pharmaceuticals and agrochemicals. The molecule’s ortho-para chlorination pattern makes it a crucial starting material for producing certain herbicides, antiseptics, and polymer additives. Some of our largest buyers channel it into further halogenation or etherification steps. They emphasize that trace byproducts can stall reactions, so our strict material handling during drying and packing has become just as vital as initial reaction purity.

    Researchers at leading institutions also report success using our 3,4-Dichlorophenol when working on flame retardant development. This application places tight controls on purity and demands reliable, scalable supply. Downstream users mention that a batch-to-batch variation as small as 0.2% can spell trouble for yields—especially in closed-loop, continuous reactor systems. As the original producer, our close monitoring at each process stage translates to tight quality bands. Feedback loops between our analytical lab and main production line prompt real changes, not just paper corrections. Countless hours spent resolving customer complaints had taught a clear lesson: only a manufacturer who controls both chemistry and logistics can secure long-term stakeholder trust.

    Comparing to Other Chlorophenols: Real-World Impact

    Compared to monohalogenated phenols—such as 4-chlorophenol or 2-chlorophenol—3,4-Dichlorophenol supplies a distinct chemical profile. Structurally, those single-chlorine analogs present alternate reactivity that influences their use as electrophiles or leaving groups in advanced syntheses. Dichlorination at the 3 and 4 positions in our product increases electron-withdrawing effects, making for a more activated aromatic ring. Synthesizing ether derivatives or acylated products from 3,4-Dichlorophenol often proceeds under milder conditions with higher yields, a point that process chemists press upon us frequently. This subtle boost in reactivity can shave days off a multi-step synthetic campaign, especially across dozens of 500-liter reactors striving for output consistency.

    Contrast this to 2,4-dichlorophenol, which often arises as a byproduct in the large-scale chlorination of phenol. Removal of trichlorinated and mixed isomers remains a persistent challenge. Our process line specifically tailors the reaction mix and temperature profile to favor 3,4-dichloro over the 2,4-variant. Rigorous fractional distillation then mops up the remaining unwanted isomers. Internal documentation shows off-spec runs when temperature calibration slips by as little as 2 degrees. Substandard competitors commonly pass through broader impurity bands, but as an original manufacturer, we have the technical discipline, and incentive, to stop these lots from leaving the site.

    Safe Handling and Operator Realities

    Daily life in production facilities has underscored certain occupational realities with 3,4-Dichlorophenol. The material, while solid at room temperature, emits a sharp, medicinal odor that signals both volatility and potential for operator exposure. Employees across packaging and handling lines receive in-depth training on personal protective equipment. We see risk mitigation as a fundamental responsibility—beyond regulatory checkpoints. Choosing robust fume hoods, closed transfer systems and modern ventilation infrastructure, we minimize airborne concentration spikes during storage or repacking. These engineering controls stem not from compliance demands, but lived workplace incidents. Our maintenance logs track any trace leaks, which we tackle aggressively to keep incident rates at zero.

    On transport, we select HDPE-lined steel drums with vapor-tight closures for long-distance road and sea shipments. Over the years, we’ve switched away from poorly-lined containers after fielding claims about surface corrosion or vapor release at destination. As a manufacturer who directly faces the consequences of leaks or lost product, our teams double down on packaging material qualifications—verifying compatibility through simulated aging and exposure trials. Every change emerges from an event or a near-miss, reinforcing the link between thorough in-house testing and shipment stability.

    Market Demand, Supply Chains and Traceability

    Over the last decade, pressure on global supply lines has put manufacturers of critical intermediates like 3,4-Dichlorophenol under the microscope. Our raw material purchasing team now sources phenol and chlorine only from a roster of vetted primary producers with transparent traceability systems. Full batch tracking accompanies each lot from tanker unloading to finished solid discharge. Regular third-party audits of our quality management system confirm process integrity—companies who purchase direct expect this level of oversight. Any suggestion of trace contamination or unapproved substitution triggers an immediate root cause analysis.

    Cycles of supply instability in the global chemical industry have pushed us toward longer-term offtake agreements and local buffer stocks. We keep several months of core input chemicals on hand, insulating regular customers from disruptions caused by hurricanes, port strikes or sudden regulatory changes. Our supply planning reflects years of navigating the chaos of upstream shortages, absorbing price spikes and capacity bottlenecks to fulfill contractual shipment schedules. Production planners meet every week with logistics coordinators, pre-empting snarls with live market data rather than reacting after delays creep up. For our direct buyers, this collaboration yields surety of supply that resellers and traders cannot match.

    Downstream Integration and Application Feedback

    One thing often overlooked in the chemical supply chain is the feedback nexus between we, the original manufacturer, and the product user. Our technical staff frequently support scale-up and application work, addressing challenges that arise only in a manufacturing or R&D environment. Several partners in the active pharmaceutical ingredient (API) space meet with us to analyze process bottlenecks when using 3,4-Dichlorophenol in intermediate steps. Adjustments to the drying profile or slight tweaks to residual moisture levels in the product have repeatedly raised yield and improved subsequent crystallization or filtration events on their lines.

    Environmental specialists working with us have conducted emissions studies tailored to their site specific use of our product, particularly for facilities converting 3,4-Dichlorophenol to downstream flame retardants or specialty polymers. By sharing in-depth impurity profiles and supporting tailored ventilation recommendations, we save our partners significant time during environmental permitting. This kind of direct engagement stands as a benefit only achievable by working with the primary manufacturer, as opposed to brokered agents or secondary resellers.

    Environmental Responsibility: Manufacturing with Awareness

    Siting and operating a multi-step chlorination and distillation facility brings environmental stewardship to the fore. We manage residual process streams containing chlorinated aromatics in on-site wastewater treatment systems designed for this class of organic pollutant. Frequent coordination with local wastewater authorities ensures our effluent levels stay well below regulatory discharge thresholds. Decades in the trade and a track record of compliance serve as proof points that original manufacturers not only build relationships on quality, but environmental responsibility as well.

    Process improvements undertaken recently include solvent recycling initiatives, heat integration of exothermic chlorination steps, and the substitution of re-circulated cooling water to reduce site-wide water consumption. Our engineering teams see these efforts not as add-ons to satisfy external auditors, but as vital means to cut costs over the long haul and build a site that can run reliably for decades without adverse local impact. We track metrics on solvent recovery and water re-use, making incremental gains that compound into longer-term wins. These measures, based on in-house innovation and application of best practices from global reference sites, distinguish a manufacturer rooted in both operational excellence and environmental ethics.

    Safety, Compliance, and End-User Confidence

    Long-term buyers care as much about the regulatory standing and documentation trail of 3,4-Dichlorophenol as they do about technical performance. Right from synthesis, we maintain detailed production logs, batch-specific Certificates of Analysis, and confirmatory third-party purity protocols where required for custom orders. Regulatory requirements governing chemical intermediates drift year by year as agencies add to restricted substance lists. Yet, our in-house compliance team keeps pace, immediately updating documents and registration files to reflect new international transportation rules or changes to safety labeling standards.

    We see it as our duty, not merely obligation, to communicate key updates to downstream partners. A recent example involved new guidance on permissible residual chloroaromatic levels for export to certain markets—our manufacturing chain adapted over a single turnaround period, swapping in upgraded condensers and improving packing systems to maintain compliance. Both process engineers and supply chain leaders invest the time and capital to ensure that 3,4-Dichlorophenol supplied under our banner supports customers’ own compliance journeys, reducing regulatory risk at every turn.

    Perspectives on Future Trends

    In our ongoing dialogue with researchers and industrial users, we see rising interest in greener synthetic protocols that use less hazardous feedstocks or enable milder reaction conditions. Some clients in the fine chemical sector investigate alternatives to halogenated aromatics, hoping for similar reactive patterns with improved ecolabel profiles. As manufacturers, we keep pace by collaborating on laboratory method development, exploring new catalytic pathways, and remaining open to pilot projects that test lower-impact processes. Authentic progress comes from hands-on collaboration, not from generic vendor declarations.

    Another evolving area involves digital monitoring and process optimization through automation. We integrate sensor feedback, automated control systems, and process data tracking into our reactor and finishing areas, spotting deviations before they hit product quality or safety thresholds. These investments do not only protect our bottom line, but directly improve the reliability and traceability of chemicals delivered to the field. As expectation for transparency grows, our customers value seeing the chain of custody and process data associated with their material. This positions us to supply not only a chemical, but a value proposition rooted in quality, safety, and continuous improvement.

    Expertise at Every Step: The Manufacturer Advantage

    End-users frequently ask what sets a genuine manufacturer apart in the supply of 3,4-Dichlorophenol. The answer comes from lived experience—witnessing how control at each production stage, engagement with feedback from the field, and willingness to invest in people and technology consolidate into a supply chain that delivers every time. The needs of researchers, process engineers, and EHS managers converge on a single point: unwavering supply of a compound with verified purity, safety, and real-world reliability. Years in the field and on the plant floor have equipped our teams with lessons that can’t be mimicked by traders or repackagers.

    The story of 3,4-Dichlorophenol at our facilities goes deeper than a technical data sheet. It is the accumulation of technical ingenuity, operational vigilance, close dialogue with users, and an ongoing responsibility toward people and the environment. Our approach remains hands-on, transparent, and responsive—qualities demanded by those who depend on our products for their own success.

    Conclusion

    The experience and dedication poured into every batch of 3,4-Dichlorophenol shape its value far beyond a commodity molecule. As manufacturers, we bring together technical insight, strong process control, robust environmental measures, and a commitment to customer outcomes—delivering a chemical that supports innovation and safe advances in research and industry.