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3,3,5-Trimethylhexamethylenediamine

    • Product Name 3,3,5-Trimethylhexamethylenediamine
    • Alias TMD-3,3,5
    • Einecs 246-675-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    520048

    Cas Number 25620-58-0
    Molecular Formula C9H22N2
    Molecular Weight 158.29 g/mol
    Appearance Colorless to yellowish liquid
    Boiling Point 220-223°C (428-433°F)
    Melting Point -27°C (-16.6°F)
    Density 0.823 g/cm³ at 20°C
    Solubility In Water Miscible
    Flash Point 102°C (216°F)
    Refractive Index 1.444 at 20°C
    Odor Amine-like
    Vapor Pressure 0.23 mmHg at 20°C

    As an accredited 3,3,5-Trimethylhexamethylenediamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500 mL amber glass bottle with a secure screw cap, labeled with safety warnings and product details for 3,3,5-Trimethylhexamethylenediamine.
    Shipping 3,3,5-Trimethylhexamethylenediamine is shipped as a hazardous chemical under UN 2280. It should be packed in approved containers, clearly labeled, and accompanied by safety documentation. During transport, avoid exposure to heat, direct sunlight, and incompatible substances. Proper personal protective equipment and spill control measures are essential for safe handling and shipping.
    Storage 3,3,5-Trimethylhexamethylenediamine should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from sources of ignition, oxidizing agents, and acids. Protect from moisture and direct sunlight. Ensure the storage area has appropriate spill containment and is equipped with safety showers and eyewash stations, and that all containers are clearly labeled.
    Application of 3,3,5-Trimethylhexamethylenediamine

    Applications of 3,3,5-Trimethylhexamethylenediamine in Industrial Manufacturing

    As a reputable chemical raw material producer, we supply 3,3,5-Trimethylhexamethylenediamine to downstream customers in several core industrial sectors. Below are the main application scenarios, each with unique compliance requirements, technical process placements, usage ratios, and resultant finished goods.

    1. Polyamide Polyurethane Elastomer Production

    This diamine is valued as a chain extender in the formulation of polyamide-based thermoplastic polyurethanes (TPUs) and cast urethane elastomers. End users select it for its influence on mechanical strength and elasticity, especially where high thermal stability is demanded, such as in automotive and industrial drive belts. Its isomeric structure provides balanced flexibility and impact resistance at elevated temperatures, influencing the polymer network cross-link density. Producers incorporate this raw material during prepolymer chain extension, adjusting the stoichiometric balance with isocyanates such as MDI or HDI, according to product specifications.

    Industry compliance standards

    • ISO 9001:2015 Quality Management for Polyurethane Manufacturing
    • REACH Regulation (EC) No 1907/2006 for chemical handling
    • Automotive OEM Material Standards (e.g., General Motors GMW15572)
    • UL 94 Flammability Testing for Polymeric Materials

    Typical usage ratio

    • 8-20 parts per hundred resin (phr), dosed relative to isocyanate equivalent weight and targeted polymer hardness; process engineers fine-tune the ratio based on required tensile properties and resistance profiles of the elastomer.

    Downstream process integration

    • Introduced during the chain extension step after prepolymer formation; thermally mixed for uniform molecular distribution, then immediately shaped by casting or extrusion under controlled moisture and temperature to prevent premature cure.

    Final product types

    • Automotive timing belts and drive belts
    • Industrial conveyor belts
    • High-flex wear-resistant technical parts (gaskets, bushings)
    • TPU-based flexible tubing for engineered machinery

    2. Epoxy Resin Curing Agent for High-Performance Composites

    Epoxy formulators use this raw material as a curing agent to impart rapid reactivity and glass transition temperature improvements in structural composites. Its steric effects provide controlled exothermic profiles and reduce brittleness, which is critical for aerospace and wind turbine composite matrix resins. Technicians dose it based on epoxy equivalent ratios, and adjust ambient cure temperature for achieving uniform polymerization and minimized shrinkage. Its performance benefits relate to improved handling time and enhanced fracture toughness in high-strength composites.

    Industry compliance standards

    • EN 9100 (AS9100) for Aerospace Composite Materials
    • ASTM D1652 & D638 for Epoxy Resin Systems
    • EN 13121 for GRP Vessels and Tanks
    • ISO 14001:2015 Environmental Management for chemical plants

    Typical usage ratio

    • 0.8-1.2 mole equivalents per epoxy group; processors may adjust lower to control exotherm in large volume castings or when extended pot-life is required.

    Downstream process integration

    • Blended into epoxy monomer systems directly prior to lay-up or filament winding; vacuum degassing and temperature ramp procedures optimize composite part quality and resin cross-linking, especially for aerospace tooling and blades.

    Final product types

    • Aerospace composite laminates and sandwich structures
    • Wind turbine blades
    • High-performance pressure vessels
    • Aerospace tooling blocks and fixtures

    3. Isocyanate-Free Polyurea Spray Coating Systems

    This amine forms the backbone of specialized polyurea coatings where rapid moisture-tolerant curing and environmental resistance are primary requirements. Industrial applicators rely on its fast reaction and formation of dense, chemically resistant films used for secondary containment linings, tank coatings, and bridge deck waterproofing. The molecule reacts immediately upon spray application with functional resins, minimizing downtime and environmental ingress in field operations.

    Industry compliance standards

    • ANSI/NSF 61 for potable water contact
    • ASTM D16 Terminology Relating to Paint, Varnish, Lacquer, and Related Products
    • ISO 12944 for Protective Paint Systems
    • EPA 40 CFR 63 Subpart PPPPPP for emission standards

    Typical usage ratio

    • 10-18 phr as a co-curing agent in the hardener component of spray-applied polyurea, balancing reactivity and final film flexibility; actual proportion adjusted to substrate type and environmental exposure risk.

    Downstream process integration

    • Stored pre-mixed in Part B of two-component spray systems; dispensed through heated, high-pressure spray guns; reacts instantly with isocyanate or resin streams to build coating thickness in seconds; field technicians monitor gel and tack-free times for full cure assessment.

    Final product types

    • Waterproofing membranes for bridge decks
    • Chemically resistant tank linings
    • Industrial floor topcoats
    • Secondary containment coatings in wastewater plants

    4. Reactive Intermediate in Specialty Polyamide Synthesis

    Downstream specialty polymer producers use this diamine as a key building block in modified aliphatic polyamides. Its steric configuration alters crystallinity and imparts improved flexibility over standard hexamethylene diamine. Used especially for high-clarity hot-melt adhesives and flexible packaging films, it is integrated in the salt formation stage prior to polymerization. Process optimization is crucial for melt stability, color retention, and extrudability, demanding strict control of feed ratios and polymerization kinetics.

    Industry compliance standards

    • FDA 21 CFR 177.1500 for Polyamide Resins in Food Packaging
    • EU Plastic Regulation (EU) No 10/2011
    • ISO 1133-1 Melt Flow Index for Polyamides
    • GMP Regulation (EC) No 2023/2006

    Typical usage ratio

    • 15-35 mol% of total diamine component, depending on balance required between softening point and film flexibility; precise proportioning is adjusted downstream by QC based on melt viscosity and mechanical test results.

    Downstream process integration

    • Added to monomer reactor with appropriate dicarboxylic acid or its salt; reacted under inert gas followed by molecular weight build-up under vacuum; post-polymerization pelletizing and quality inspection ensure batch-to-batch consistency for further extrusion or compounding.

    Final product types

    • Hot-melt adhesive pellets
    • Flexible retort packaging films
    • Polyamide-based cable jacketing compounds
    • Technical textile coatings for filtration
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    Certification & Compliance
    More Introduction

    Meeting Industry Needs with 3,3,5-Trimethylhexamethylenediamine: Manufacturer’s Perspective

    Why This Diamine Matters in our Industry

    Many chemical processes lean on aliphatic diamines for stability, performance, and end-use durability. As a manufacturer committed to consistency and reliability, we have spent years refining 3,3,5-Trimethylhexamethylenediamine production, not just to meet expectations but to anticipate where performance makes a real difference. Engineering teams across coatings, adhesives, polyurethane elastomers, and specialty resin sectors keep seeking improvements in reactivity and final product characteristics. From our experience, nothing quite matches the unique combination of structural stability, ease of incorporation, and accelerated reactivity that 3,3,5-TMHD brings to their systems.

    Experienced Manufacturing Yields Consistent Performance

    Producing diamines at high purity starts with feedstock selection and critical operational control. Our 3,3,5-Trimethylhexamethylenediamine emerges from an established synthesis process using tightly controlled temperatures, pressure regimes, and purification steps. Over time, we invested heavily in automation and dosage accuracy, which brings clarity to our product—from colorless to light yellow liquid, low amine number deviation, and minimized moisture. The model we primarily supply reflects a purity parameter at or above 99%, with each batch tracked for amine content using direct titrimetric methods.

    Impurities such as water, secondary amines, and related linear diamines get managed below strict thresholds because even small traces can initiate side reactions in isocyanate-based systems. That extra vigilance shows in batch-to-batch reproducibility, which partners count on. Feedback from industry formulators shows a clear preference for diamines with less than 0.2% water since every fraction above this can cause internal bubbles and impaired crosslinking. In high-performance epoxy and polyurethane resins, the significance of water and other low-level impurities becomes obvious—not only do mechanical properties suffer, but shelf stability and application lifetime also drop. Each specification reflects these operational hard lessons, not market requests alone.

    Usage in Polyurethanes, Epoxies, and High-Performance Polymers

    Urethane and epoxy system formulators pursue a narrow range of polyamine reactivities. 3,3,5-Trimethylhexamethylenediamine supports the design of fast-reacting, impact-resistant coatings and cast parts. Its branched structure—three methyl groups at strategic positions on the hexamethylenediamine backbone—delivers unique reactivity that outpaces standard linear diamines. Compared with common hexamethylenediamine, the three methyl groups disrupt crystallinity and increase molecular free volume. The shift in structure helps customers who require faster gel times, reduced brittleness, or greater chemical resistance after full cure.

    Every year, advancements in construction and automotive polyurethanes ask for improved cure speed and flexibility. Using our 3,3,5-Trimethylhexamethylenediamine allows formulators to shorten pot life without sacrificing workable open time. Coating manufacturers report higher gloss retention and better performance against UV light in accelerated weathering trials. In composite resin systems, end users achieve denser, crack-resistant profiles—especially important in specialty flooring and marine parts. Electronics encapsulation and high-voltage insulation specifiers also point to TMHD for improved tracking resistance and electrical insulation, which come from its unique ability to reduce water absorption.

    What Sets 3,3,5-Trimethylhexamethylenediamine Apart

    A common question from downstream specialists involves the direct performance comparison between 3,3,5-Trimethylhexamethylenediamine and more familiar diamines such as hexamethylenediamine or isophoronediamine. In our long production history, it has become clear that TMHD carves out its own category. The extra methyl substituents bring tangible benefits in several areas. Manufacturers of structural adhesives admire its ability to accelerate post-cure without promoting run-away exotherms. Those working in cast polyurethane elastomers note improved long-term resilience at both low and high temperatures.

    Processing plants serving electronics demand diamines with specific glass transition properties and low ionic contamination. Our product’s low nitrogenous by-product content ensures that post-cure conductivity does not stray outside tolerance, and electrical resistivity remains high. Unlike standard hexamethylenediamine, which tends to introduce excess rigidity or hydrolytic instability, TMHD’s branched structure responds well to both dynamic and static stress. Molders handling advanced composites have shared accounts of its easier polyol incorporation, with less phase separation and fewer surface imperfections. Product runs stay cleaner, and part rejections drop.

    From the Operator’s View: Practical Benefits and Handling Insights

    Commercial plant operators have a direct relationship with this diamine’s handling properties. Since its boiling point and viscosity enable clear metering, even in large-volume systems, transfer losses become negligible with standard heated lines. No strong amine odor pervades working areas due to advanced bottom-nitrogen stripping during our process. Formulators running semi-automated mixlines appreciate the mild volatility and uniform flow through dosing pumps. Transparent supply chain reporting stands behind every drum—real-time batch analytics, full trace documentation, and responsive quality support keep operations on time.

    Every technician knows the frustration of out-of-specification purity or variable amine basicity, especially with the growing focus on consistent polymer morphology. We dedicate significant plant time to calibration and amine-value checks that directly impact downstream reaction kinetics. The reality for commercial users: reliable TMHD shipments keep downstream reactors from foaming, eliminate inconsistent gel points, and reduce the adjustment cycles needed to achieve specification polymer properties. From an industrial perspective, solvent compatibility matters—TMHD works smoothly with common organic solvents, and minimal fouling occurs in mixing vessels.

    Feedback Loops: Listening to Real-World Needs

    Continuous feedback from customers running high-throughput lines has shaped every update to our process. For example, customers processing large casting volumes raised concerns about trace impurities leading to microbubble formation in final products. We responded by integrating multi-stage water removal and adding in-line spectrometry to tighten control beyond classic Karl Fischer titrations. Years of these process optimizations have built trust. Resin manufacturers scaling from pilot to full production value predictable viscosity and color, so we invested in advanced monitoring and inner drum lining to preserve stability until use.

    Further up the value chain, specialty adhesive developers describe the lower color index of TMHD as a game-changer for optically clear applications. Consistency in hue and performance parameters has prompted engineering groups to switch from traditional linear diamines. For polyurethane elastomer use, end-users look for a balance of fast reactivity and end-use flexibility. Field trials highlight improved rebound resilience and enhanced compression set after long-term use. These observable improvements emerge from our plant-level control of methyl branching and elimination of high-boiling side products during purification.

    Addressing Key Challenges in Diamine Manufacturing

    Running a production plant has taught us how even tiny variations can multiply across downstream synthesis. Protecting against oxidation during storage matters, not only for product shelf life, but also for minimizing amide formation in final applications. We store our diamine under dry inert gas to avoid nitrogenous oxidation, and every drum gets date of fill and seal-tamper evidence. From our experience, the market’s move toward higher automation and digital process integration means less room for error—so every bit of plant data, from raw materials to final fill, is continuously monitored and traceable.

    Customers in regions with temperature extremes rely on stable product handling. TMHD’s modest melting point and stability under moderate heating mean that the product stays flowable in both cold and warm climates. We learned—after years of worldwide shipments—that material handling teams want straightforward dosing, with no fuss over phase changes during transfer. Adding anti-static drum liners and improved tight-head closures has solved shipping safety complaints in export markets, which keeps the supply chain moving.

    Comparing 3,3,5-Trimethylhexamethylenediamine to Other Diamines

    Technical comparisons reveal that traditional diamines such as hexamethylenediamine offer lower viscosity and less chain branching, leading to stiffer, more crystalline network formation. This profile fits commodity resins but falls short for specialty elastomers and impact-resistant adhesives. By contrast, isophoronediamine yields strong mechanical stability but suffers from increased color formation over time and higher UV sensitivity.

    In practical terms, teams using TMHD see improved resistance to embrittlement and better chemical tolerance across acidic and alkaline exposures. Not every application needs these advantages, but for performance-critical products in automotive, marine, and electronics, choices based on structure and purity matter most. Our process refines the product to a clarity and amine number range that avoids pitfalls of linear analogues and provides meaningful differentiation in demanding roles.

    Sustainability and Safe Manufacturing: Looking to Tomorrow’s Standards

    Modern manufacturing shifts increasingly toward minimizing environmental footprint. We have cut vented emissions and energy usage per ton of TMHD produced by optimizing catalyst recovery, heat exchangers, and waste water recycling loops. Processing teams inside our plant know that solvent management impacts permit compliance and workplace safety. Using in-process abatement units, we capture fugitive amines during distillation, which pays back through both regulatory compliance and improved site health.

    We partner with supply chain and waste partners to keep container reuse and safe cleanout routines. Each run goes through multiple safety and performance checks, including simulated shipment vibration and temperature cycling, to confirm stable delivery. Our warehouse and filling teams monitor every unit for leak-tightness and unexpected contamination, preventing issues before product leaves the plant. Years of independent audits across occupational and environmental safety standards have confirmed our closed-loop approach.

    End-User Insights and Application-Specific Stories

    The varied feedback from our long-term partners provides a clear picture. Polyurethane process engineers often mention reduced cycle time and fewer finishing defects on flexible foam and elastomer lines. Rigid foam formulators track density and closed-cell content improvements, attributing much of this progress to reliable TMHD supply. Electronics encapsulation experts consistently report improved dielectric properties in side-by-side testing, citing both lower ion contamination and enhanced hydrolytic resilience. Every one of these gains ties back to practices developed and refined inside the plant, not theoretical changes.

    Paint and coatings chemists highlight the importance of color stability and storage life in competitive markets. Our product’s consistent color and low haze make it a favorite for specialty clear coatings and high-quality anti-graffiti paints. Outside the lab, contractors praise the reliable cure and lack of residual odor, speeding up job completion in public and sensitive environments. The feedback loop between direct users and our plant leads to new procedures, frequent specification reviews, and continual equipment updates.

    Supply Reliability and Commitment to Partner Support

    Downtime costs everyone throughout the value chain. Our shipping, technical, and sales teams understand the cost of stockouts, so we run expanded storage and logistics management. Every drum of TMHD in our warehouse is tracked digitally from incoming raw material to outgoing shipment, with full backup supply available during seasonal demand spikes. This kind of process transparency keeps communication lines open and supports production planning for our partners.

    Beyond simple delivery, our technical specialists offer on-site support, troubleshooting, and tailored blend recommendations. Each year brings new challenges as requirements shift—efficiently screening new applications for TMHD in partnership with customers keeps our team at the front line of industry needs. From the view of the plant floor to the application chemist, establishing open exchange has proven most effective in solving real-world processing and product quality problems.

    Innovation and Product Development: Direct from the Source

    Chemical manufacturing means persistent experimentation and constant adaptation. We watch trends in flexible coatings, faster-setting adhesives, and more durable composite materials not from afar, but alongside those developing and using them. Every process improvement in TMHD production—whether better water removal technologies, advanced impurity tracking, or smarter packaging—comes from listening to partners and solving specific processing pain points.

    Our product development does not end at standard specification sheets; it runs in step with downstream trials and ongoing support after the shipment arrives. Whether it’s feedback about a newer catalyst where TMHD’s specific steric profile improves selectivity or a resin system in need of tighter gel time controls, every challenge drives our R&D team to push further.

    Closing Reflections from Within the Industry

    No two days in chemical manufacturing look quite the same. Direct responsibility for product quality and consistency gets forged on the plant floor, between equipment adjustments and periodic specification reviews. The trust we build through careful TMHD production persists through countless downstream product launches—some successful, some demanding new approaches or incremental improvements.

    Our experience, from the earliest trial runs to the widest commercial distribution, has repeatedly shown that 3,3,5-Trimethylhexamethylenediamine bridges real market needs with technical performance demands not met by standard offerings. Every process control point, each documented specification, and all customer feedback loops speak to a deep investment in producing more than just a commodity chemical. The story continues—with every drum leaving our plant fueled by a drive for quality, partnership, and purposeful improvement in specialty manufacturing.