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2-Tert-Butyl-4,6-Dinitrophenol

    • Product Name 2-Tert-Butyl-4,6-Dinitrophenol
    • Alias Dinitrobutylphenol
    • Einecs 221-273-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    747810

    Cas Number 88-85-7
    Molecular Formula C10H12N2O5
    Molecular Weight 240.21 g/mol
    Iupac Name 2-tert-butyl-4,6-dinitrophenol
    Appearance Yellow crystalline powder
    Melting Point 108-110 °C
    Solubility In Water Poorly soluble
    Density 1.37 g/cm³
    Synonyms Dinoseb, Dinosebe, DNBP
    Odor Characteristic phenolic odor
    Flash Point 170 °C (closed cup)
    Hazard Statements Toxic if swallowed, harmful to aquatic life
    Pubchem Cid 8750
    Logp 4.2

    As an accredited 2-Tert-Butyl-4,6-Dinitrophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle labeled "2-Tert-Butyl-4,6-Dinitrophenol, 100g." Includes hazard warnings, CAS number, and safety instructions.
    Shipping 2-Tert-Butyl-4,6-Dinitrophenol is shipped as a hazardous material, typically in tightly sealed containers to prevent moisture and contamination. It must be packaged according to regulations for toxic and potentially explosive substances, with appropriate labeling and documentation. Transport is carried out by authorized carriers with safety precautions to minimize risk during transit.
    Storage 2-Tert-Butyl-4,6-Dinitrophenol should be stored in a tightly closed container, in a cool, dry, well-ventilated area away from heat, ignition sources, and incompatible substances such as strong oxidizers or acids. Protect from light and moisture. Clearly label the container, and restrict access to trained personnel. Use appropriate secondary containment to prevent spills or leaks.
    Application of 2-Tert-Butyl-4,6-Dinitrophenol

    Applications of 2-Tert-Butyl-4,6-Dinitrophenol in Industrial Manufacturing

    2-Tert-Butyl-4,6-Dinitrophenol has specialized roles in several segments of the chemical industry, serving as an essential component in controlled synthesis and technical formulations. Below we present detailed application fields, each following specific regulatory, compositional, and production requirements for quality downstream utilization.

    1. Polymerization Inhibitors for Vinyl Monomers

    This compound functions as a polymerization inhibitor in the storage and transport of acrylate, styrene, and other reactive monomers, reducing unwanted self-polymerization during transit and extended holding at production sites. Our customers employ it in both bulk and continuous processing within polymer plants, requiring precise addition to maintain monomer purity and prevent process line blockages. Manufacturers must dose the inhibitor based on monomer reactivity, system temperature, and expected storage duration. Quality management includes ongoing residue analysis to avoid excess carryover into downstream resin synthesis.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006—Annex XVII restrictions
    • OSHA CFR 1910.1200—Hazard Communication Standard
    • ISO 9001:2015 quality management for chemical intermediates
    • American Chemistry Council Responsible Care® guidelines

    Typical usage ratio

    • 5–100 ppm, adjusted based on monomer type, temperature, and anticipated storage period

    Downstream process integration

    • Added to monomer storage tanks prior to shipment or during bulk unloading at the polymer plant
    • Monitored through inline detection systems or regular sampling for inhibitory content analysis

    Final product types

    • Market-grade methyl methacrylate monomer (MMA)
    • Industrial styrene monomer batches
    • Functionalized acrylate monomers for paints and adhesives

    2. Intermediate for Synthesis of Agricultural Chemicals

    This raw material acts as a nitroaromatic intermediate in multi-step synthesis routes of specific substituted phenol herbicides and limited high-selectivity molluscicides. Agrochemical manufacturers integrate the compound in controlled reaction sequences, where strict conditions minimize byproduct formation and environmental release. The institute safety data, waste stream remediation, and compliance with application-specific agrochemical regulations form the core parts of the production process for downstream technical concentrate synthesis and further formulation.

    Industry compliance standards

    • ISO 9001 and 14001 for agrochemical intermediate handling
    • EU Regulation (EC) No 1107/2009—Plant Protection Product approval
    • China GB 2763—Maximum Residue Limits for Pesticides in Food
    • FIFRA (US EPA Federal Insecticide, Fungicide, and Rodenticide Act)

    Typical usage ratio

    • As a synthetic intermediate—stoichiometric quantities; varies 0.3–1.2 molar ratio depending on target product pathway

    Downstream process integration

    • Used in stepwise nitration, reduction, and coupling reactions in chemical synthesis lines
    • Levels monitored for precursor exhaust and trace compliance in technical concentrate output

    Final product types

    • Selective herbicide active ingredients
    • Specialty pesticide technical concentrates

    3. Photographic Chemicals and Dye Manufacture

    The product serves as a chemical auxiliary in the formulation of high-performance photographic developer baths and select organic dyes, especially in processes where controlled redox properties are vital. Manufacturers in this sector follow tight dosage regimens to prevent unintentional overexposure or color shift during emulsion treatment and dye coupling. Continuous quality oversight is required to keep impurity profiles within accepted photographic industry specifications and colorant standards.

    Industry compliance standards

    • ISO 9001 for fine chemical manufacturing
    • ISO 18902:2013—Imaging materials—Processed photographic papers
    • EN 71-3:2019+A1—Migration of certain elements in dyes
    • REACH Annex XVII for dye additive restrictions

    Typical usage ratio

    • 10–40 mg/L in developer baths, adjusted to silver halide sensitivity and desired image stability
    • 0.2–3% w/w for dye synthesis, based on color base reactivity

    Downstream process integration

    • Blended into developer bath concentrates during mixing phase
    • Introduced to dye precursor solutions under controlled pH and temperature

    Final product types

    • Gelatin-based photographic print and film developers
    • Custom azo and anthraquinone dyes for textile and paper application

    4. Performance Additive in Lubricant Formulations

    Chemical process engineers apply this substance as an antioxidant and stability modifier for industrial grease and select specialty lubricants intended for high-load or high-temperature use. Proper handling and metering at blending sites prevent excessive oxidation and thermal degradation of the formulated lubricant. Technical users ensure all operators adhere to safety and environmental protocols, given the potential toxicity of nitroaromatic compounds in finished lubricant systems.

    Industry compliance standards

    • ISO 21469—Hygiene requirements for lubricant formulation
    • REACH Regulation Annex XIV-XVII as applicable to lubricants
    • ASTM D4951—Phosphorus, Calcium, Zinc, and Sulfated Ash in lubricants
    • API 1509/ACEA engine oil standards (for industrial lubricants)

    Typical usage ratio

    • 0.01–0.09% w/w based on base oil type, target oxidation stability, and application stress conditions

    Downstream process integration

    • Dosed directly during grease compounding or lubricant concentrate mixing
    • Stability and dispersal of additive verified via lab oxidation and performance tests

    Final product types

    • Extreme-pressure industrial greases
    • Specialty compressor and turbine lubricants

    5. Controlled Laboratory Reagent or Reference Standard

    Chemical laboratories and accredited QC facilities utilize the compound as a specialized reference standard or reductive agent during analytical method development and calibration in industrial hygiene, environmental testing, and synthetic route verification. Accurate weighing and documentation ensure result traceability and method reliability, with all handling and storage performed following laboratory-specific safety protocols and validated method requirements.

    Industry compliance standards

    • ISO/IEC 17025 laboratory competence
    • Good Laboratory Practice (GLP) OECD Series
    • USP and BP reference standard control where analytical chemistry applies
    • GHS/CLP hazard communication for laboratory reagents

    Typical usage ratio

    • 1–50 mg per calibration or test run, dependent on method sensitivity and test volume

    Downstream process integration

    • Dosed during analytical standard preparation for method calibration
    • Stored and logged under controlled environment for traceable use

    Final product types

    • Certified reference standards for environmental, health, and industrial quality testing
    • Analytical batch controls for custom method development
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    Certification & Compliance
    More Introduction

    2-Tert-Butyl-4,6-Dinitrophenol: Our Perspective as Makers

    Introduction to 2-Tert-Butyl-4,6-Dinitrophenol

    Walking through the plant, the distinct, pungent smell of dinitrophenol lingers in the air, signaling another batch of 2-Tert-Butyl-4,6-Dinitrophenol taking shape. Anyone who’s handled it day in and day out knows the yellow powder by touch and sight. The model that sees the most action in our lines is the direct result of work done on batch purity, crystallization methods, and continual tuning of reaction conditions to balance product consistency with scalable output. We know how much users in polymers, specialty intermediates, and advanced materials depend on a grade they can trust, and our operations reflect years of feedback from chemists in the field and process engineers on the ground.

    Our main focus stays fixed on purity, particulate uniformity, and reproducibility. Here, every lot is checked for contaminants, residual solvents, and expected melting point. Feedback from partners who synthesize antioxidants, stabilizers, or initiators has taught us how even small shifts in impurity levels can shift colorimetric readings or trigger unexpected byproducts. It took repeated rounds of solvent selection and post-filtering to reduce not just nitrophenol isomers, but metal traces left from old filter bags. Many years ago our team moved away from single-pass syntheses to more staged, multi-reactor refining to get the active component above the 99% purity mark preferred in technical and research markets today.

    Real-World Usage

    People often ask what sets this compound apart in complex molecule synthesis, plastics, or as a stabilizer. There’s no trick, just experience—drawn from years seeing how researchers and industrial end-users actually use 2-Tert-Butyl-4,6-Dinitrophenol. Its role as a building block for specialty additives in plastics and specialized adhesives is common. The bulky tert-butyl group on the phenol ring, combined with two nitro substituents at the ortho positions, creates a blend of steric protection and electron-withdrawing effect. This makes it favorable for formulations needing resistance to oxidative breakdown, and for cases leaving standard dinitrophenols vulnerable.

    Colleagues in polymer R&D have used this molecule to give polymers better high-temperature endurance, or to improve safety in flame retardant blends. It's not simply a case of swapping in another phenolic stabilizer—its chemical architecture does something unique. Technicians who have struggled with degradation of less-substituted analogs note the difference right away, especially under heat-laden extrusion cycles or UV exposure. In our feedback logs, one theme comes up again and again: better stability, more predictable end results, fewer surprises when scaling up production.

    Specification Matters: What We Measure and Why

    Anyone in chemical manufacturing knows every lot needs to hit exact standards. Our team controls batch temperature, reaction time, and pressure with real-time monitoring, keeping impurity levels as low as practical. Even though it takes more effort and cost, we sample at each stage—reactant input, nitro substitution, isolation—checking for color, melting range, and active ingredient percentage.

    One key practical lesson: color alone isn’t a reliable purity predictor. Early in operations, samples with similar pale yellow hues showed starkly different GC profiles. Continued solvent washing and staged crystallization had a direct impact, not only reducing color variability but eliminating masked impurities that hampered downstream reactions in customer labs. Labs relying on HPLC or GC, whether in university or on a polymer plant floor, send direct feedback when off-spec material disrupts processing. We’ve stopped nearly a dozen batches before shipment just from slight shifts in our detector response, based on these end-user reports.

    Researchers often spot the odd batch out through changes in melting point. Our plant protocol flags even a minor shift below 109°C for further investigation. People working in flame retardancy or high-end polymer applications have no tolerance for batch-to-batch differences. Long-term, this diligence has shrunk customer complaints, improved product traceability, and kept our figures for rejected inventory lower than industry averages.

    Differences From Other Dinitrophenol Compounds

    Some buyers ask why they shouldn’t just use other dinitrophenol variants. Anybody who has spent time on a synthesis bench with substituted phenols, or mixed batches for commercial processes, recognizes the quirks each structural tweak brings. The tert-butyl group in this molecule isn’t just a decorative tag—it sets the entire chemical behavior apart. Standard 2,4-dinitrophenol accepts nucleophilics at both ortho and para positions, often proving less stable in harsh processing environments. In contrast, the tert-butyl substitution raises the product’s resistance to side reactions, which matters in formulations exposed to light, ozone, or high heat.

    Technicians who have switched from unsubstituted dinitrophenols to our product in flame-retardant resins, for example, point to tougher resistance against yellowing, greater process latitude, and a notable drop in failure rates during long-term weathering tests. Direct feedback from coatings manufacturers also shows improved gloss retention and shelf stability, with less need for post-additive stabilization. Not every downstream chemist needs this higher resistance profile, but those who do now demand it as a routine part of their spec sheet. We’ve seen, from batch trials, how less-substituted variants can lead to discoloration or failure in late-stage processing, forcing unplanned downtime and waste.

    If price per kilogram is the only limit, undifferentiated technical dinitrophenol seems attractive. The real calculation unfolds only after factoring in yield, rework, and durability of finished goods. The higher initial cost of 2-Tert-Butyl-4,6-Dinitrophenol pays back through lower scrap rates and longer product lifespans—echoed widely by our commercial partners who share real-world figures after a year or two in full-scale operation.

    Industry Adoption and Regulatory Insights

    Spending time with environmental compliance officers, we’ve learned careful attention must be paid to product composition. Nitrophenol derivatives occasionally spark concern due to their reactivity and regulatory history. Over the years, international standards have shifted, focusing more narrowly on permissible impurity content and safe handling protocols. Rather than see this as a nuisance, our plant incorporates additional purification passes, scales up wastewater capture, and logs lifecycle-impact assessments for each synthetic step.

    Direct engagement with regional authorities, and hearing from end-users grappling with ever-changing restrictions, pushed us toward greener solvents and continuous-improvement audits on both emissions and waste treatment. While many in the industry try to skate by with the minimum, we’ve chosen to stay ahead, publishing batch analytics and supporting partners with environmental documentation that stands up to scrutiny in most advanced markets. This openness builds longer, steadier business—even if it means slower approvals or unplanned engineering upgrades.

    But regulations can flip without warning. Our shipping teams keep chemical hazard communication updated at all times, and during audits, our veteran operators can walk any inspector through every measured residual, test result, and corrective action if limits are exceeded. Someone looking for off-spec, gray-market product won’t find it coming from our dock doors.

    Scaling Production: On the Floor Realities

    Few outside manufacturing see the labor behind a high-purity dinitrophenol output. During busy months, our reactors run around the clock, and maintaining a safe, controlled synthesis demands both precision and experience. Bottlenecks don’t come just from complex chemistry, but from the delicate balance between throughput, cleaning cycles, and staff rotations. Equipment fouling, unexpected reaction runs, and raw material variability are facts of life. To tackle these, our site shifted to modular reactors years ago, letting us sidestep downtime if one line hits a snag.

    Plant operators, many of whom have grown with the company over decades, share a preference for preventive maintenance and detailed operational logs. Early warning sensors for temperature deviations, unusual pressure spikes, or off-color filtrates get logged and acted on in real time. The process improvements aren’t high-tech for technology’s sake—they directly reflect what saves batches and reduces rework. Only operators who have had to dump out half-cured product after an unnoticed condenser blockage truly appreciate systems that alert them to trouble before it ruins a shift’s output.

    Challenges and Continual Improvements

    Chemicals like 2-Tert-Butyl-4,6-Dinitrophenol draw attention for both their benefits and hazards. Internally, our safety team works hard to coach new hires—proper PPE, careful spill containment, and waste minimization are drilled into every crew. Lessons are often learned the hard way. Equipment upgrades such as closed transfer systems and vapor recovery reduce both risk to personnel and emissions to the environment.

    The market gives us a push, too. Some years, demand swings high with a major run on specialty stabilizers or international customers seeking dual-sourcing for strategic supply assurance. Our sales team fields frequent questions about lead times, supply reliability, and post-delivery technical support. Drawing on decades in the business, we answer with real figures—how much output we can realistically promise, what reserve stocks exist, and what sorts of order variability can be absorbed without incident. Any promises we make stand behind a commitment to never ship substandard product.

    Supporting Partners in Innovation

    Our longest relationships have come from working side-by-side with partners pushing new industrial applications. Joint research efforts, on-site trials, and even customer-initiated reformulation projects have shaped how the product itself has evolved. In one case, field failures from a less robust antioxidant in a specialty polymer led a client’s R&D team to test 2-Tert-Butyl-4,6-Dinitrophenol as a substitute. After months of shared trials, modified dosing, and pilot-scale runs, their failures in field exposure testing dropped sharply, and their confidence in stable supply rose.

    Experience shows it is never about chasing the lowest price per kilo, but building a relationship where technical feedback flows freely and improvements get made in weeks, not years. New opportunities arise as partners design more demanding formulations. Transparency—about strengths, limitations, hazards—has become our strongest selling point.

    Moving Toward Sustainable Synthesis

    In line with environmental shifts across the sector, our plant has made steady progress toward greener chemistry. Classic nitration routes, though productive, yielded more hazardous byproducts and consumed more solvent. Recent years have brought process intensification, lower-emission catalysts, and on-site recycling modules that lower wastewater loads and improve energy efficiency. Technicians and plant engineers run on-site trials for every chemistry tweak—in several rounds, modifications trimmed solvent requirements by a quarter. Less hazardous waste leaves the fence line, and local water treatment worries have eased.

    Any move to improve the green profile tracks metrics in real time—kg waste per batch, solvent recovery ratio, and overall process energy per ton output. The business case doesn’t sit on blind guesswork, but on five years of internal metrics and honest environmental audits. Our management keeps one eye on regulatory risk, but more so, keeps an ear to staff feedback. Taking shortcuts rarely pays off, and frontline operators can spot trouble long before software triggers an alarm.

    What Collaboration Looks Like

    Some people outside chemical manufacturing assume all suppliers act the same—with rigid specs and closed-door process details. Our approach has always been open book. When new clients approach us with unusual solubility requirements or need to integrate the product into reactive extrusion processes, our technical teams visit, gather plant data, and act as problem solvers. Whether the challenge lies with downstream compatibility or unexpected functional group reactivity, deep technical experience makes the outcome less about selling product and more about helping customers build something truly novel.

    We have seen, through countless trials, where 2-Tert-Butyl-4,6-Dinitrophenol shines and where it runs into limitations. Instead of just shipping boxes, we share what works from our own and our partners’ trials—real numbers, actual failure cases, possible tradeoffs between purity and throughput. Many research partners have become friends and long-term collaborators. Shared wins grow business tougher than any one-off transaction.

    How User Experience Shapes Our Direction

    Longtime users talk about reliability, but what this means on the floor is flexibility in mixing, fewer unexpected downtime events, and certainty a process runs to the same endpoint batch after batch. Formulation specialists handling advanced resins notice fewer “mystery” side reactions, color drifts, or shelf-life failures. Troubleshooting batch inconsistencies, our support team draws on decades’ logs—comparing reaction conditions, material properties, and field performance of products produced years apart. Continuous engagement, not one-off product drops, builds the confidence that keeps our customers coming back.

    Conclusion: A Manufacturer’s Ongoing Commitment

    We produce 2-Tert-Butyl-4,6-Dinitrophenol for users who value reliability, transparency, and genuine partnership. The work doesn’t stop at meeting batch specs—it extends into everyday problem-solving, regulatory compliance, process safety, and collaborative advances in green chemistry. Nobody gets it right every time, but we hold ourselves to higher standards, constantly tuning not only products and processes but relationships with those who trust us as supplier, technical resource, and partner for the long haul. From plant floor to end-user application, every step reflects a dedication to quality that decades of experience have taught us cannot be replaced.