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2-Ethylhexylamine

    • Product Name 2-Ethylhexylamine
    • Alias Ethylhexan-2-ylamine
    • Einecs 206-235-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    613505

    Cas Number 104-75-6
    Molecular Formula C8H19N
    Molar Mass 129.24 g/mol
    Appearance Colorless to pale yellow liquid
    Odor Amine-like
    Melting Point -70 °C
    Boiling Point 184-186 °C
    Density 0.79 g/cm³ at 20 °C
    Solubility In Water Moderate (1.9 g/L at 20 °C)
    Flash Point 69 °C (closed cup)
    Vapor Pressure 1.7 hPa at 20 °C
    Refractive Index 1.425 at 20 °C

    As an accredited 2-Ethylhexylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 2-Ethylhexylamine is packaged in a 500 mL amber glass bottle with a screw cap, clearly labeled with hazard warnings and details.
    Shipping 2-Ethylhexylamine is shipped in tightly sealed containers, typically drums or intermediate bulk containers (IBCs), under ambient conditions. It should be transported in compliance with regulations for flammable and corrosive liquids. Containers must be clearly labeled, protected from physical damage, and stored upright to prevent leaks or spills during transit.
    Storage 2-Ethylhexylamine should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from heat, sparks, open flames, and incompatible substances such as acids and oxidizing agents. Protect from direct sunlight and moisture. Store on spill containment trays and clearly label containers. Use secondary containment and ensure appropriate chemical-resistant shelving and storage areas.
    Application of 2-Ethylhexylamine

    Applications of 2-Ethylhexylamine in Industrial Manufacturing

    2-Ethylhexylamine supports a wide range of value chains in the chemical industry, serving as a critical intermediate in multiple downstream applications. As a direct manufacturer, we ensure strict quality controls and product consistency to fulfill complex process and compliance requirements.

    1. Agrochemical Synthesis (Herbicide and Pesticide Production)

    Producers of agricultural chemicals utilize 2-ethylhexylamine primarily as an intermediate for the synthesis of active ingredients in herbicide and pesticide formulations. In these processes, amination reactions using this chemical generate a variety of acid amine salts that exhibit strong weed and pest control properties. Advanced purification ensures compliance with restrictive impurity profiles. Production batches typically adjust amine content to optimize reactivity and downstream product yield based on crop-specific formulation portfolios and regional agronomic conditions.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • REACH Regulation (EC 1907/2006) Registration and Use Restrictions
    • China GB 2763 Maximum Residue Limits
    • ISO 9001:2015 Quality Management for Agrochemical Intermediates

    Typical usage ratio

    • 5–20% by reaction mass in amine salt formation; formulation and application rate determined by specific active ingredient synthesis and intended formulation strength

    Downstream process integration

    • Added during condensation or neutralization stage for direct salt formation, following in-process amine quality testing
    • Purification and solvent stripping steps before transfer to formulation for precise dosing
    • Quality control assays measure amine purity and potential side-products

    Final product types

    • 2-Ethylhexylamine salt herbicides (e.g., 2,4-D 2-ethylhexylamine salt)
    • Selective pesticide active intermediates
    • Agrochemical amine adducts for improved crop coverage
    • Formulated herbicide mixtures for large-scale agriculture

    2. Rubber Vulcanization Accelerator Manufacture

    In rubber processing, downstream manufacturers employ 2-ethylhexylamine in the synthesis of vulcanization accelerators, such as sulfenamides and thiurams. These accelerators require precise amine-to-thioacid ratios. The reaction affords rapid curing systems for technical rubber goods, maintaining performance at elevated temperatures. Stringent batch traceability and impurity controls are necessary due to the critical role of accelerators in industrial rubber mechanical properties.

    Industry compliance standards

    • ASTM D4678 Vulcanization Accelerator Quality Standards
    • ISO 9001:2015 Rubber Additives Quality Control
    • EU REACH SVHC Certification (Substances of Very High Concern)
    • China GB/T 2941 Rubber Compounding Ingredient Standards

    Typical usage ratio

    • 3–10% by weight in precursor reaction mixtures, adjusted based on end-use accelerator activity and rubber compound design requirements

    Downstream process integration

    • Charged during sulfenamide or thiuram synthesis via batch or continuous reactor
    • Post-reaction extraction and filtration for accelerator purification
    • QC verification of accelerator purity before compounding with elastomer matrices

    Final product types

    • Accelerators for tire manufacturing (e.g., CBS-2EH)
    • General-purpose rubber accelerator blends
    • Technical rubber parts (seals, hoses, belts)
    • Automotive and industrial rubber goods

    3. Fuel Additives and Lubricant Formulation

    The fuel and lubricant industry incorporates 2-ethylhexylamine as a key intermediate in the production of ashless dispersants and fuel additive packages. Manufacturers synthesize polyisobutylene succinimide derivatives using the amine for improved engine cleanliness and particulate suspension in modern combustion systems. The dosage depends on the specific product’s performance grade and the intended base oil characteristics. Strict controls ensure no residual amine remains in the finished package to conform with emission and ash content regulations.

    Industry compliance standards

    • API SN/CF and ACEA Lubricant Quality Specifications
    • ASTM D2887 Fuel Additive Compatibility
    • US EPA Registration for Fuel Additives
    • ISO 9001:2015 Lubricant Manufacturing Quality Control

    Typical usage ratio

    • 2–8% by mass within additive concentrate synthesis; adjusted based on dispersant molecular weight and engine test requirements

    Downstream process integration

    • Fed into polyisobutylene anhydride imidation and subsequent blending with additive components
    • In-line quality monitoring for complete reaction and purity assurance
    • Blending and filtration before packaging and distribution

    Final product types

    • Diesel and gasoline detergent additives
    • Heavy-duty engine oil dispersants
    • Low-ash lubricant additive systems
    • Combined multifunctional lubricant additive packages

    4. Corrosion Inhibitor Intermediate for Water Treatment

    Industrial water treatment formulators use 2-ethylhexylamine as a core building block in the synthesis of organic corrosion inhibitors, especially in the preparation of fatty amine derivatives for closed-loop and open recirculating systems. The material reacts with fatty acids or phosphate esters, yielding high-film-strength inhibitors. Formulators calculate the amine-to-acid feed ratio to balance inhibitor hydrophobicity with strong surface adsorption, critical for industrial cooling and boiler operations. All output undergoes rigorous effluent and toxicity testing.

    Industry compliance standards

    • ANSI/AWWA B511 Standard for Corrosion Inhibitors
    • REACH Annex XVII Water Treatment Substance Restrictions
    • US EPA TSCA Certification for Environmental Acceptability
    • ISO 14001:2015 Environmental Management System Compliance

    Typical usage ratio

    • 5–15% by weight during inhibitor synthesis; selection based on water system scale, desired protective film thickness, and anticipated pH fluctuations

    Downstream process integration

    • Added in batch esterification or amidation stage with fatty acid or phosphate raw materials
    • Post-reaction purification and pH adjustment prior to inhibitor blending
    • QC includes inhibitor performance and environmental safety assays

    Final product types

    • Organic amine-based closed-loop corrosion inhibitors
    • Cooling water additive blends
    • Industrial boiler anti-scalant packages
    • Customized film-forming inhibitor concentrates

    5. Pharmaceutical Intermediate for API Synthesis

    The pharmaceutical sector relies on 2-ethylhexylamine in the manufacture of certain active pharmaceutical ingredient (API) intermediates, especially within local anesthetic and antihistamine production. The amine group enables selective alkylation and amide bond formation steps. Precise monitoring of input quantity and reaction purity is mandatory for compliance with pharmacopoeial monographs and GMP batch release criteria. Equipment cleaning validation prevents potential cross-contamination in multipurpose manufacturing settings.

    Industry compliance standards

    • United States Pharmacopeia (USP) and European Pharmacopeia (Ph. Eur.) Standards
    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • China Pharmacopoeia (ChP) API Purity Guidelines
    • US FDA 21 CFR Part 210/211 cGMP Regulations

    Typical usage ratio

    • 1–5 molar equivalents relative to carboxylic acid/ester precursors; optimized to ensure complete conversion and minimal by-product formation, as confirmed by HPLC analysis

    Downstream process integration

    • Introduced during selective alkylation or amidation reaction steps
    • Registered in electronic batch manufacturing records and traceability databases
    • Residual amine monitoring by validated chromatographic methods before API purification

    Final product types

    • Amide intermediate for anesthetic APIs (e.g., articaine, lidocaine derivatives)
    • Intermediates in antihistamine synthesis
    • Other specialty amine-based pharmaceutical intermediates
    • Quality-verified fine chemicals for further pharmaceutical synthesis

    6. Flotation Agent in Mining Processing

    Mineral processing plants apply 2-ethylhexylamine in the preparation of specialty flotation agents designed for the separation of rare earths and non-ferrous metal ores. The unique alkyl chain promotes selective adhesion to target mineral surfaces in alkaline process conditions. Dosing rates must account for ore composition, pulp density, and downstream dewatering requirements. Application protocols require on-site adjustment according to ore body variability and ensure environmental discharge meets strict regional standards.

    Industry compliance standards

    • China GB 20416.1–2006 Standards for Flotation Chemicals
    • ISO 9001:2015 for Mining Reagents Manufacturing
    • EU REACH Compliance for Mining Agents
    • National Environmental Discharge Permits (e.g., China MEP)

    Typical usage ratio

    • 0.1–0.5 kg reagent per ton of processed ore; values optimized by laboratory bench flotation trials and plant-scale performance feedback

    Downstream process integration

    • Dosed directly into ground ore slurry during rougher and scavenger flotation stages
    • Field-monitoring for residual amine levels in process water and tailings
    • On-site adjustment of dosage based on ore feed mineralogy changes

    Final product types

    • Rare earth mineral concentrates
    • Non-ferrous metal sulfide and oxide concentrates
    • By-product flotation agent blends
    • Mine site flotation chemical supply programs
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    Certification & Compliance
    More Introduction

    2-Ethylhexylamine: A Closer Look from the Manufacturer’s Perspective

    What Sets Our 2-Ethylhexylamine Apart

    Manufacturing chemicals is an art grounded in science and shaped by experience. Every batch tells a story, and with 2-ethylhexylamine (2-EHA), that story begins with careful synthesis and attentive purification. Over years in the chemical manufacturing landscape, we've learned how critical material consistency and purity are for downstream processes, especially in demanding sectors like pharmaceuticals, agrochemicals, rubber processing, or coatings. Our 2-ethylhexylamine—CAS number 104-75-6—emerges as a clear, colorless to pale yellow liquid with a characteristic amine odor, and our production practices focus on maintaining low impurity profiles to ensure reliability for our customers’ needs.

    Model and Specifications: Built on Experience

    Our core product specification developed from listening to formulators and process chemists who need confidence in every intermediate they handle. We produce 2-ethylhexylamine with a minimum purity threshold of 99% by GC. Moisture control is key, so we monitor water content closely, typically below 0.3%. This focus directly responds to issues observed in the field, where excess water can lead to unwanted side reactions—particularly in sensitive syntheses or when forming salts. By stringently controlling this, we help minimize waste and troubleshooting time at the user end.

    Amines, especially aliphatic ones like 2-EHA, have a tendency to absorb carbon dioxide and moisture from the atmosphere, which can cause yellowing or create off-spec profiles. To address this, we invest in robust drum and IBC sealing technology, not as an afterthought, but as a direct response to feedback from users who have faced disappointing product stability with other sources. This packaging focus means customers find the material in a usable state, drum after drum, even after transit across seasons and climates.

    Applications: More Than a Building Block

    2-Ethylhexylamine finds its way into a wide range of end uses. In working with clients from agriculture to healthcare, we hear time and again that supply consistency spells the difference between a process that scales and one that whimpers out in the pilot stage. Our involvement doesn't end with shipping a drum; we routinely discuss reaction outcomes and troubleshoot color issues, odorous byproducts, or solubility challenges that may stem from trace impurities in amine streams.

    In the rubber industry, for example, 2-EHA comes up often as an accelerator. By delivering high-purity material, we help keep polymerization reactions predictable. There’s little room for error—side products or excess moisture in the amine can hamper polymer length and elasticity, so our QC team monitors every batch with these real-world effects in mind.

    Paint and coatings manufacturers use 2-ethylhexylamine in the synthesis of fungicides, pesticides, and corrosion inhibitors. Product consistency shows its value most clearly when clients remark on batch-to-batch color uniformity, reactivity in downstream syntheses, and manageable amine odors during blending. These outcomes stem from years of in-house process improvements—backed up by regular user feedback and iterative product adjustments.

    In the pharmaceutical and agrochemical spheres, synthetic intermediates demand tight control over byproducts. Here is where our continual improvement process kicks in; we implement extra purification steps, not due to regulatory pressure, but because clients experimenting with tiny changes in synthetic routes have brought us credible, data-driven insights showing the negative effects from even parts per million of certain side products. These lessons make their way back to our plant floor and analytical lab workflows.

    Why 2-Ethylhexylamine Offers Unique Solutions

    We often get asked to compare 2-ethylhexylamine with other aliphatic or branched amines—like n-butylamine, isopropylamine, or dodecylamine. The distinction is not academic. In practice, the bulky, branched C8 structure of 2-EHA means it brings a lower volatility and a higher boiling point compared to lighter amines—attributes that lend stability and slower evaporation. That helps when a process needs an amine present through a heated or extended reaction cycle.

    From a reactivity standpoint, the steric hindrance introduced by the ethylhexyl group can make 2-EHA less nucleophilic than smaller alkylamines, which often reduces unwanted side reactions, especially in the manufacture of amide linkages or during quaternization stages. In finishing applications where odor matters, like treating textiles or formulating cleaning agents, this translates into a less aggressive smell profile. This nuance has grown from our close collaboration with customers seeking to balance effectiveness and work environment quality.

    We’ve seen multiple clients try to switch out 2-ethylhexylamine for other primary amines in order to cut costs. Many end up returning, having found that the reaction selectivity, product shelf life, or odor management fall short when using substitutes. Learning directly from these challenges has prompted us to streamline our customer support, supplying not just material but the underlying chemical understanding that saves time and reduces trial-and-error in the lab or production hall.

    From Core Process to Reliable Supply

    Our commitment to manufacturing excellence goes beyond merely meeting a spec sheet. Each process step, from hydrogenation to final distillation, invites careful monitoring and real-time adjustments. If a batch strays even slightly from expected odor or color, our team investigates cause and effect. For instance, high-pressure hydrogenation requires exacting control over catalyst lifetimes and feed rates—a lesson that only comes from running hundreds of campaigns and noting the subtle links between process tweaks and end-use behaviors.

    On the shop floor, operators track not only throughput but also the evolving demands of downstream applications. One learning that stands out: process reliability today depends on anticipating tomorrow’s regulatory or market shifts. Increasing scrutiny on amine purity in food or pharma settings has pushed us to invest in higher-end instrumentation, like GC-MS and advanced water content analyzers. Clients benefit through traceable, consistent product that meets obligations beyond the minimum spec—especially under changing legislative frameworks in Europe, the Americas, and Asia.

    There’s a lot of attention on environmental and worker safety now. We offer guidance, drawn from our own handling protocols, on how best to work with 2-EHA’s vapors, skin contact risks, and the right static management in the warehouse. Beyond talking safety, we share knowledge in waste minimization practices—for users keen on reducing solvent loads or seeking greener reaction conditions. These innovations don't spring from thin air; they are the direct output of our team’s willingness to revisit root process design and open conversations with users, regulators, and local communities.

    Supply Chain, Storage, and the Realities of Bulk Handling

    Most people in labs focus on grams in a beaker, but our crew manages tankers, IBCs, drums—sometimes hundreds of tons at a time. Storage forces us to confront realities that don’t show up in textbooks. 2-Ethylhexylamine, for all its stability, will yellow and thicken over time if left exposed to the air. That’s why every shipment gets a fresh nitrogen blanket and desiccant inserts, especially for overseas journeys. Our logistics team tracks seasonal temperature shifts and modifies shipping schedules so that no barrel sits near freezing or under fierce sun on an airport tarmac.

    We also recognize that each end-user faces unique onsite restrictions. Many have told us stories of off-spec or difficult-to-open packaging causing downtime and additional labor costs. These conversations push us to invest in easy-drain drums, robust locking mechanisms, and anti-tamper seals—incremental improvements emerging directly from practical, on-the-ground feedback.

    Handling questions rarely feel theoretical. During the COVID-19 era, global supply chains buckled. We found ourselves fielding urgent requests to resupply major clients at short notice, forging new regional stockpiles and backup partnerships. A reliable amine source keeps production lines moving for manufacturers who can’t afford to pause operations. Our flexibility and transparency—on batch traceability, anticipated lead times, and quality retesting—proved essential to maintaining trust through market upheaval.

    Challenges: Keeping Purity High and Costs Manageable

    Maintaining the delicate balance between purity, batch consistency, and cost drives much of our internal debate. The push for higher purity specifications carries both production and analytical cost implications. Distillation cuts, storage tank maintenance, and in-process water removal build up the cumulative expense, yet returning to a lower bar isn’t feasible—the performance of the end product suffers. So, we keep our operations lean, with regular training for every reactor and filtration operator, so they spot anomalies before they become compliance risks or safety hazards.

    Waste management represents another challenge. Every kilogram of unwanted byproduct burdens our treatment units and impacts the local environment. Engineers constantly review reaction yields, separation efficiency, and vent gas capture rates. Recovery and reuse programs for offcuts or distillation residues continue to grow, fueled by regulatory changes and our own commitment to responsible manufacturing. The lessons learned through waste audits end up improving next year’s process, often in small, underappreciated ways that quietly reduce both footprint and cost.

    Rising raw material prices ripple through the whole operation. In response, we negotiate long-term supply contracts for starting materials like 2-ethylhexanol, and diversify sources for hydrogen and catalysts. This allows us to dampen market volatility and pass on fewer surprises in our pricing. We keep open channels with both suppliers and end users to warn about anticipated changes, drawing from our market intelligence not just to cushion risk for ourselves but also for our clients.

    Regulatory and Environmental Footprints

    2-Ethylhexylamine falls under many watchful eyes in regulatory circles. Experience tells us that documentation and traceability are as crucial as the molecule itself. We invest now to pre-register, maintain up-to-date REACH documents, and formalize transport safety protocols. Many users come to us with urgent requests for data sheets or toxicological data ahead of a new tender or downstream audit. We're able to respond in hours, not days, because our compliance staff keeps meticulous files and updates every finished batch’s documentation and MSDSs as soon as standards change or new studies emerge.

    From an environmental angle, our plant upgrades target emission cuts and water treatment improvements. Amine emissions carry both odor and toxicity risks, particularly in densely populated zones. We’ve installed vapor scrubbing systems and work with local committees to keep operations accountable. By monitoring how small procedural changes influence output—both inside the plant and outside in the community—we turn practical experience into continual improvements.

    Collaborative Product Development: Shaping Tomorrow’s Use Cases

    Our technical staff thrives on user input to improve both the process and the end product. A recent partnership with a specialty surfactants company led to subtle changes in how we stabilize 2-EHA for improved shelf life in non-polar solvent blends. By welcoming site visits from downstream application engineers, not just sending out drums, we've captured subtle but valuable insights—better antifoaming behavior, more controlled reactivity in epoxy curing, or decreased odor in closed-system blending.

    Each time our users describe a process hiccup or demand for a tighter impurity profile, that knowledge channels directly to our R&D bench. There’s no rigid wall between plant engineers and business development in our organization; every batch complaint or success story lands at the same desk. Years spent in this iterative loop teach us that 2-ethylhexylamine is not simply a commodity or a datasheet value—its real-world advantage comes from this flexible, attentive relationship between producer and user community.

    2-Ethylhexylamine: Facts That Matter

    From the eye of experience, the merits of 2-ethylhexylamine rest on details that shape every stage from tanker to test tube. Its balance of hydrophobic and hydrophilic character enables its use as an intermediate for emulsifiers, antiseptics, corrosion inhibitors, and flotation agents. Unlike many other amines, its scent profile is less volatile, often favored in settings where user comfort near open reactors can't be overlooked. Consistent feedback points to trouble with smaller amines flashing off or generating regulatory headaches in workplace safety audits—a headache 2-EHA mostly avoids.

    Boiling point sits at 158-160°C, which opens uses in applications demanding thermal stability alongside strong nucleophilicity. Its density and viscosity match up well with automated pumping and weighing systems, two process details that might sound minor until you’re the operator handling dozens of bulk transfers a week.

    Longevity matters for every buyer. Through years of supply to pharmaceutical plants and crop protection R&D groups, we’ve linked shelf life to container choice and storage location. With robust packing protocols, our 2-EHA keeps its clarity and reactivity over long periods, aligning quality with customer expectations, batch after batch.

    Differences That Count: User Feedback in Action

    Rather than list theoretical improvements, we focus on the most common user-driven comparisons with alternatives. The highly branched, bulky structure of 2-EHA unlocks slower evaporation and a more manageable vapor phase profile. Our clients in resin and rubber compounding report fewer issues with premature crosslinking or erratic viscosity shifts during scale-up versus materials like n-butylamine.

    There’s also the matter of side reactions. Chemists have detailed for us how certain branched amines, including 2-EHA, reduce polycondensation rates in specific polyurethane syntheses, widening the window for controlled process checks prior to curing—a tangible process benefit. End users producing biocides and surfactants cite improved final product clarity and longer shelf stability due to the lower presence of secondary and tertiary amines, achievable through our refined distillation steps.

    Many of these enhancements stem not from theoretical calculation but from persistent attention to user process feedback and in-plant observations over time. No two factories or labs have the same pain points, but recurring themes in odor, reactivity, or batch drift propel our upgrades and guide each investment.

    Toward a Strong Future: 2-Ethylhexylamine in a Changing World

    Industry never stands still. Regulatory climates, supply chain disruptions, and evolving chemistries shape what manufacturers need from primary aliphatic amines. Our 2-ethylhexylamine production process doesn’t remain fixed; each year brings fresh investment in cleaner processes, smarter purification workflows, and more transparent product documentation—all in direct response to the real-world requirements and practical advice of our global user base.

    Having supplied countless tons of 2-EHA to multiple continents, we understand every hiccup along the way—from drum swelling in tropical shipping, to off-color complaints linked to drum headspace oxidation. These experiences mold not only how we make and deliver every batch, but also how we collaborate with users, troubleshoot obstacles, and design the next generation of process improvements. For us, manufacturing means staying hands-on, open-minded, and always ready to adapt, so that every batch of 2-ethylhexylamine brings practical, measurable value to those who transform it day in and day out.