Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2-Cresol

    • Product Name 2-Cresol
    • Alias o-Cresol
    • Einecs 200-453-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    133054

    ChemicalName 2-Cresol
    OtherNames o-Cresol, ortho-Cresol, 2-methylphenol
    MolecularFormula C7H8O
    MolarMass 108.14 g/mol
    CASNumber 95-48-7
    Appearance Colorless to yellowish liquid
    MeltingPoint 30.8 °C
    BoilingPoint 191 °C
    Density 1.05 g/cm³ (at 20 °C)
    SolubilityInWater 22 g/L (at 20 °C)
    RefractiveIndex 1.5399 (at 20 °C)
    VaporPressure 0.23 mmHg (at 25 °C)
    FlashPoint 81 °C (closed cup)
    Odor Medicinal, phenolic

    As an accredited 2-Cresol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 2-Cresol is packaged in a 500 mL amber glass bottle with a secure, chemical-resistant screw cap and caution labeling.
    Shipping 2-Cresol should be shipped in tightly sealed, corrosion-resistant containers, protected from heat, sparks, and open flames. It is classified as a hazardous material and must be handled according to local, national, and international regulations. Proper labeling, documentation, and use of secondary containment are required to prevent leaks and environmental contamination.
    Storage 2-Cresol should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from heat, sparks, open flames, and incompatible substances such as oxidizing agents and acids. The storage area should be clearly labeled and access restricted to trained personnel. Protective measures should be taken to prevent leakage or spills, as 2-Cresol is toxic and flammable.
    Application of 2-Cresol

    Applications of 2-Cresol in Industrial Manufacturing

    2-Cresol serves as a vital intermediate in various chemical industries. Its reactivity, purity, and industrial availability support major downstream manufacturing processes. As the original producer, we ensure uniform material characteristics suited to each application.

    1. Agrochemical Intermediates

    2-Cresol is widely processed into herbicides, insecticides, and fungicides. It participates in the synthesis of cresoxyacetic acid and other phenolic agrochemicals. Manufacturers require consistent purity to prevent side reactions during chlorination and etherification stages. Our grades facilitate direct integration into batch synthesis lines for crop protection agents.

    Industry compliance standards

    • REACH (EC 1907/2006) for chemical safety in EU markets
    • US EPA TSCA Inventory for agricultural intermediates
    • China GB 2763 for allowable residues in pesticides
    • ISO 9001:2015 certified process control

    Typical usage ratio

    • Applied in 15–25% molar ratio, based on target molecule structure and desired yield during downstream coupling or alkylation. Adjusted according to process optimization and required product selectivity.

    Downstream process integration

    • Introduced during nucleophilic substitution or etherification step following base-catalyzed deprotonation.
    • Handled in closed reactors to minimize emissions.

    Final product types

    • Herbicides (e.g., phenoxyacetic acid derivatives)
    • Insecticides (chlorinated cresol-based active ingredients)
    • Fungicides containing cresol derivatives
    • Plant growth regulators produced from phenolic precursors

    2. Resin and Polymer Manufacturing

    Downstream producers use 2-cresol in the condensation polymerization to form specialty phenolic and cresol-formaldehyde resins. These resins serve high-heat and electrical insulation uses. Stringent control of cresol isomer ratios maintains resin performance in demanding applications such as brake pads and circuit board substrates. Our pure-feed material supports repeatable polymer chain length and crosslinking density.

    Industry compliance standards

    • UL 94 Flammability Standard for resins in electronics
    • IEC 60216 thermal endurance for insulation materials
    • RoHS Directive (2011/65/EU) for restricted substances
    • ASTM D1610 for phenol-formaldehyde resin quality

    Typical usage ratio

    • Incorporated at 10–18% by weight relative to total monomer mix in resin copolymerization; manufacturers adjust depending on desired crosslink density and final hardness.

    Downstream process integration

    • Added to reactor prior to aldehyde feed during bulk or emulsion polymerization.
    • Quality monitored via residual monomer content and glass transition temperature (Tg) measurements.

    Final product types

    • Thermoset molding compounds (brake pads, gear wheels)
    • Electrical laminates and circuit board substrates
    • Adhesive resins for automotive industry
    • Coatings and films for corrosion resistance

    3. Antioxidant Additive Synthesis

    Industrial producers synthesize various phenolic antioxidants from 2-cresol, particularly for use in lubricating oils and rubber. The process frequently involves alkylation or condensation to create hindered phenol structures. Quality and color stability depend on cresol feed consistency. Our supply supports continuous, high-volume antioxidant manufacturing with minimized impurity carry-over.

    Industry compliance standards

    • ASTM D611 for aromatic compound identification
    • FDA 21 CFR 172.615 for antioxidants in food-contact lubricants
    • ISO 21469 for safety of machinery lubricants
    • Automotive OEM material specifications (e.g., VW TL 52145)

    Typical usage ratio

    • Consumed at 23–35% molar ratio depending on target antioxidant; higher ratios may apply to hindered phenol synthesis for improved heat resistance.

    Downstream process integration

    • Charged into batch reactors alongside alkyl chains or co-reactants during main condensation step.
    • Purity monitored to avoid color instability in finished lubricants.

    Final product types

    • Phenolic antioxidants (BHT analogues, alkylated phenols)
    • Lubricant stabilizers for engines and turbines
    • Polymer and rubber compounding antioxidants
    • Food-grade lubricant additives (with food-safe grades)

    4. Disinfectant and Preservative Formulations

    2-Cresol serves as an active precursor and blending component in industrial disinfectants and wood preservatives. Producers use it for its broad-spectrum biocidal effect and water solubility manipulation. Our high-purity grades allow manufacturers to formulate emulsions and concentrates with consistent standardized activity levels for healthcare, livestock, and construction industries.

    Industry compliance standards

    • EN 1276:2019 for bactericidal activity in disinfectants
    • US EPA 40 CFR 180 for antimicrobial chemical registration
    • WHO Model List of Essential Chemicals for Health Sector
    • BS EN 13986 for wood-based panel preservatives

    Typical usage ratio

    • Employed at 5–12% by weight in disinfectant concentrates and 3–7% in wood treatment solutions, adapted to required biocidal spectrum and regulatory maximum limits.

    Downstream process integration

    • Dosed during final blending alongside surfactants and emulsifiers in continuous or batch mixers.
    • Subject to in-process quality checks for active content and flash point.

    Final product types

    • Hospital-grade surface disinfectants
    • Livestock barn-cleaning solutions
    • Antifungal wood preservatives (creosote oils, cresol emulsions)
    • Industrial machinery wash fluids

    5. Dye and Pigment Intermediate

    2-Cresol acts as a key raw material in the synthesis of azo and triphenylmethane dyes for leather, textile, and printing segments. The aromatic hydroxyl group enables sulfonation and coupling with diazonium salts. We guarantee narrow impurity profiles and controlled isomer ratios to support reproducible dye properties and vivid color outcomes.

    Industry compliance standards

    • OEKO-TEX Standard 100 for restricted dye substances
    • EU REACH Annex XVII for azo dye precursors
    • ISO 105-B02 for color fastness testing
    • ZDHC MRSL for sustainable textiles

    Typical usage ratio

    • Participates in 10–20% molar ratio in dye coupling reactions, adjusted per hue intensity and desired fastness level. Lower ratios apply when used as a coupling component rather than as the main chromophore base.

    Downstream process integration

    • Fed directly into sulfonation or nitration steps before diazotization.
    • Material handled in glass-lined or stainless steel vessels for purity retention.

    Final product types

    • Acid and direct dyes for wool, silk, and cotton
    • Leather finishing colorants
    • Printing inks (solvent-based and water-based)
    • Azo pigment intermediates

    6. Pharmaceutical Intermediate

    2-Cresol provides an essential starting material for antiseptic drugs, expectorants, and synthetic APIs. Its hydroxyl and methyl substituents allow efficient halogenation, etherification, and condensation for pharmaceutical intermediate production. Our strict QC protocols assure trace-level impurity control and documentation under applicable pharmacopeial guidelines.

    Industry compliance standards

    • USP–NF for pharmaceutical raw materials
    • European Pharmacopoeia (Ph. Eur. 10.0)
    • ICH Q7 GMP for APIs
    • FDA 21 CFR Part 211 for finished pharmaceuticals

    Typical usage ratio

    • Processed at 8–15% molar ratio in synthesis of targeted active or antiseptic ingredient, strictly based on reaction route and yield requirements.

    Downstream process integration

    • Charged in initial or intermediate step, typically in halogenation or ether-substitution reaction chains.
    • Batch records and full traceability supplied per cGMP practice.

    Final product types

    • Pharmaceutical antiseptics (e.g., chlorocresol)
    • Mucolytic agents (expectorants)
    • API intermediates for cough syrups and topical antiseptics
    • Preservatives for ophthalmic and injectable formulations
    Free Quote

    Competitive 2-Cresol prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2-Cresol: Trusted Quality from the Manufacturer’s Bench

    From Our Reactors: What Sets Our 2-Cresol Apart

    2-Cresol begins as a clear-to-yellowish crystalline solid, its phenolic sharpness distinct as any chemist who’s handled it will tell you. We produce 2-Cresol in several purity ranges from 98% to 99.5%, and over decades in synthesis and distillation, we focus heavily on controlling the meta/para isomer ratio and residual water levels. Every batch is realized through continuous distillation under nitrogen blanketing, minimizing oxidation and impurities. We stick to this because 2-Cresol as an industrial intermediate can turn up abnormalities if the storage or transfer lines allow the slightest air ingress. When you ship a drum, customers expect the same raw purity and minimal off-note content that originally left the reactor—lax handling isn’t an option if you want to keep reaction profiles predictable.

    Why Specifications Matter in Everyday Production

    In alkylated phenols and copolymer resins, any deviation in 2-Cresol composition translates directly into batch-to-batch drift. Too much moisture and customers see frothing in their reactors; too much ortho isomer and antioxidant performance changes in rubber vulcanization. That’s why we stick to closed systems and invest in good in-process analytics. GC-FID runs for every lot catch even slight co-boiling tails or impurity peaks other methods might miss. Consistency lets downstream customers avoid fiddling with recipe adjustments, which keeps overall production costs—and cumulative downtime—down to a dull roar.

    How We Use Our Experience to Raise the Bar

    Over years of customer feedback and performance audits, we’ve seen recurring pain points. Some users—especially those formulating agrochemical intermediates—run into polymerization or tinting problems with off-spec 2-Cresol. Residual iron or copper, even at single ppm levels, can taint the oxidative stability of finished goods. We reengineered our equipment for full stainless-steel contact and zero non-ferrous contamination. Water content, often an afterthought, gets tracked with Karl Fischer titration on every drum, since even half a percent can throw off sodium cresolate formation or disrupt certain coupling reactions. Getting these details right helps us build repeat reliability for formulators who can’t afford lost batches.

    What Makes 2-Cresol a Pillar in Chemical Synthesis

    Anyone operating a phenolic plant knows that 2-Cresol—chemical name ortho-cresol or 2-methylphenol—underpins a lot of value chains. Its ability to act as a nucleophile and stabilize intermediates means it finds its way into flame retardants, pesticide active ingredients, and major polymer backbones. In antioxidants (like BHT and related stabilizers), small variances in 2-Cresol feed purity can make a night-and-day difference in long-term color retention and shelf life. A few customers make their own phenol-cresol-formaldehyde novolacs; they report noticeable improvements in adhesive bond strength and clarity when switching from unlined mild-steel drums to our internal epoxy-lined packaging, where 2-Cresol stays free of trace contaminants. These are the kind of details we’ve come to know from overseeing hundreds of reaction campaigns, not gleaned from catalogs.

    Direct Handling Keeps Quality in Our Hands

    We handle the full lifecycle of 2-Cresol from feedstock to shipment. Our process starts with methylation of phenol using carefully dried feedstocks, using nickel-catalyzed vapor-phase routes rather than older batch alkali fusion methods. This persistence on vapor-phase methods gives tighter control on cresol homolog distribution, slashing meta- and para- content and delivering a cleaner ortho cut—something smaller outfits with batch glass-lined reactors can’t manage at scale. Every batch is tracked, logged, and sampled according to a protocol refined over years of actual production headaches, not software templating.

    Customers Shape Our Adjustments, Not Market Fads

    Over years we’ve fielded questions about “dual-purpose” cresol blends or “universal” phenol intermediates. We find formulas built for everyone usually shortchange specific industrial outcomes. When a big surfactant producer had issues with herbicide emulsification, their analysis pointed to suboptimal cresol purity—residual para-cresol affected solubility behaviors. Fast-tracking a tighter ortho/para separation fixed their plant yields. In fungicide precursor chemistry, slight shifts in base titratable acidity (from moisture or phenolic autocondensation) can torpedo yield. Refining control over feed neutralization and expanding retention times in distillation columns gave them a reliably pure product without extra reworks or surprises.

    Physical Form and Packaging Tailored to Downstream Need

    Since 2-Cresol can solidify below 30°C, we offer both liquid and semi-solid drum types. Some customers in colder regions opt for mild warming blankets for drum storage, while others using large tote tanks demand ready-to-pump clear liquid. For customers using automated dosing, we engineered lined drums that prevent leaching, keeping finished product free from polymerization or color shifts after resealing. We notice that big jobs—latex modifiers or high-volume resin runs—run into less downtime with our bulk tank shipments, real-world experience from plant managers who have learned to avoid filters clogging with solidified cresol residue.

    Comparing 2-Cresol With Related Products

    Within the cresol family, each isomer—ortho, meta, para—delivers different reaction and physical properties. Some operations prefer meta-cresol or para-cresol for plasticizer or dye intermediates, chasing slight changes in boiling point or solubility. We stress that 2-Cresol’s methyl group at the ortho position gives unique reactivity in phenolic resins, especially where steric hindrance makes a difference in final chain architecture. For medical disinfectants or wood preservatives, the sharper antiseptic action and solvent miscibility of 2-Cresol edge out other isomers. We’ve seen customers attempt jobbing with generic cresol blends only to double back for dedicated ortho product purity to meet local regulatory limits or end-use requirements. A lesson repeated enough times that we design purification columns, not just to standard, but to customer-driven specifications.

    Our Safety and Environmental Stewardship—Drawn Directly from Plant Realities

    Any manufacturer in the phenolics trade knows the environmental and handling stakes: 2-Cresol is a skin/respiratory irritant and not something to treat lightly. We spent years designing storage and venting that prevent emissions, with direct recovery on vent streams and automated drum purging before shipment. It cuts our VOC losses and gives customers product that won’t set off alarms at their own sites. Wastewater isn’t an afterthought here—every production run routes spent wash first through stripping, then biological treatment, so the plant effluent meets or beats local regulations.

    A Word on Regulatory and Sustainability Challenges

    Our compliance teams work shoulder to shoulder with production to ensure our 2-Cresol meets global regulatory frameworks—REACH, EPA, and beyond. This isn’t paper shuffling; it means tracking precursor and waste flows, running quarterly full-spectrum impurity scans, and pulling in third-party auditors for random spot checks. Demand for renewable phenol sources is on the rise, and we’re running bench-scale pilots using bio-based routes to ortho-cresol. It’s early, and scale constraints remain, but customer priorities shift fast; our job as a direct producer is to keep ahead of these curves as processes mature.

    Applications: A Snapshot from Customer Uses

    Direct users span agrochem, resins, adhesive, stabilizer, and medical disinfectant markets. Downstream, our ortho-cresol goes into synthesizing fungicides, carving agents for polymer electronics, and stabilizers for lubrication oils. Resin labs often report that our narrower isomer cut allows more reproducible curing, whether for circuit board lamination or pressure-sensitive adhesives. One example: a tire compounder making antioxidant blends switched from imported multi-isomer cresol and shaved weeks off their production downtime because of the better shelf stability and less fouling of their mixing extruders.

    Reliability That Shows in Customer Uptimes

    Real-world plant managers talk about uptime, not certificates. Our most loyal customers aren’t persuaded by glossy brochures—they look at drift in product specs, downtime from out-of-spec drums, and avoidable color or odor issues showing up in the final product. After investing in tighter process controls and more robust analytical support, we cut average batch deviation by half in two years, translating to less rework downstream and fewer headaches for anyone trying to make time-sensitive intermediates.

    Investments in R&D Sharpen Product Reliability

    Years of handling complaints from users running specialized coupling reactions, where trace sulfur or halide contaminants can alter yields, led us to overhaul our purification train. By adding a dedicated sulfur scrubbing column and off-spec tank routing, we carved out a niche in high-purity, low-halogen cresol for pharma and advanced materials. This didn’t come from theory—it came from walking customer lines, collecting resin samples, troubleshooting plant polymerization anomalies, and folding those lessons back into our reaction monitoring logic.

    In-House Technical Support—A Direct Manufacturer’s Advantage

    Unlike brokers or holding companies, we keep technical staff right next to our synthesis lines, not in a remote office. If a batch doesn’t meet typical reactivity, or the customer’s process develops an unexpected color, our in-house technical team can run side-by-side bench trials with the actual material shipped. This proximity allows us to solve technical pain points with real, actionable tweaks—like adjusting distillation cut points, or tweaking packaging according to a user’s pump compatibility—instead of passing the buck or hoping a generic recommendation smooths things over.

    Trouble-Shooting in the Field: Lessons We Pass Down

    There isn’t a year that goes by without a customer running into an “unusual” incompatibility—2-Cresol clouding out in polymer blends if mixed too quickly, or micro-leaks in storage tanks causing stress cracking or off-odors. As direct producers, we maintain logs of field fixes: proper agitation rates, preferred types of drum gaskets, or dehumidification tips for storage rooms, drawn from plant audits and on-site troubleshooting, not a technical library. Many of our current best practices—using nitrogen blanketing on partial drums or setting up simple circulation heaters—trace back to fixes we’ve developed by getting our hands dirty alongside plant operators.

    Why Real-World Data Trumps Vendor Promises

    Every year, generic sellers flood the market with promises of “technical grade” or “high-purity” 2-Cresol. Customers eventually confront the gaps between specification sheets and actual field performance. We routinely run impurity mapping and track factors like acid value, color index under light storage, and non-volatile residue—critical for resin and adhesive makers. Customers who tried lower-priced, broker-sourced drums often find haze, unexpected polymerization, or color instability after a month on-site. Practiced buyers return to direct sources like us, looking for transparent auditing data and a clear chain of custody.

    Supply Stability Built from Ground Up

    Feedstock swings, global shipping delays, and new waste regulations have all upended the status quo in the phenolic intermediates world. Because we own our supply—from raw phenol to finished 2-Cresol—there’s backup at every node. On the production side this means redundant reactor lines, slack built into the maintenance schedule to prevent surprise shutdowns, and multi-region sourcing contracts that shield against spikes in phenol pricing or port blockages. We don’t just weather supply chain storms—we build against them, because consistency downward enables efficiency upward for our partners.

    Sample Testing for Process Critical Applications

    For customers taking 2-Cresol into new or highly sensitive synthesis, we encourage pilot sampling—sending not only a typical drum but off-take from different sides of the production campaign, so formulation chemists can verify reaction rates, spectral matches, and storage stability with confidence. A pharmaceutical intermediate customer once detected trace aldehyde content we hadn’t seen before; post-mortem tracked it to a minor spike in upstream phenol oxidation, prompting a protocol revision for pre-feed dewaxing and filtering. These learnings benefit not just one, but our entire downstream user base.

    Meeting Tomorrow’s 2-Cresol Demands: Innovation Born On-Site

    The world is shifting. Environmental scrutiny tightens, customer specifications become finer, and process automation drives expectations for lower manual intervention and higher traceability. From our vantage point on the production floor, innovation means blending classic engineering with digital monitoring—retrofitting distillation columns with inline spectrometers, integrating real-time water content checks, and using remote alarms to detect minor leaks before they lead to customer returns. The R&D roadmap isn’t about trend-watching; it’s about translating gritty production upsets and hard-won customer feedback into every new feature and improvement.

    Continuous Improvement—Driven By Those Who Rely On Our Product

    We keep a strong feedback loop open. Chemists who run precision blends for electronic polymers, plant managers overseeing hundreds of tons in adhesive or biocidal synthesis, and QA staff tracking impurity spikes rely on us to keep our standards high. We regularly revisit our process analytics, invest in better packing and storing safeguards, and open the plant floor to third-party audit—so the 2-Cresol our team ships tomorrow matches what customers count on today. This ethos has kept our product at the front line of demanding industrial use, not just as a raw commodity but as a partnership asset in the hands of innovators and line workers alike.