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2-Chloro-M-Cresol

    • Product Name 2-Chloro-M-Cresol
    • Alias 3-Chloro-6-methylphenol
    • Einecs 202-588-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    962085

    Chemical Name 2-Chloro-M-Cresol
    Cas Number 87-60-5
    Molecular Formula C7H7ClO
    Molecular Weight 142.58 g/mol
    Appearance White to off-white crystalline powder
    Boiling Point 234-236°C
    Melting Point 56-58°C
    Density 1.31 g/cm³
    Solubility In Water Slightly soluble
    Flash Point 110°C
    Smiles CC1=CC(=C(C=C1)O)Cl
    Iupac Name 2-chloro-3-methylphenol

    As an accredited 2-Chloro-M-Cresol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 2-Chloro-M-Cresol is packaged in a sealed, amber glass bottle containing 100 grams, with a clear hazard label and lot number.
    Shipping 2-Chloro-m-Cresol should be shipped in tightly sealed containers, clearly labeled with hazard information. Store and transport in a cool, well-ventilated area away from incompatible substances. Handle according to regulations for hazardous materials, ensuring appropriate packaging and documentation for ground, air, or sea freight. Wear suitable protective gear during handling.
    Storage 2-Chloro-m-cresol should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers. Keep it away from heat, sparks, and open flames. Store in a designated chemical storage area with proper labeling, and avoid exposure to moisture and direct sunlight. Always follow local regulations for chemical storage.
    Application of 2-Chloro-M-Cresol

    Applications of 2-Chloro-M-Cresol in Industrial Manufacturing

    2-Chloro-M-Cresol serves as a specialized chemical intermediate and preservative in select industrial manufacturing sectors. As direct producers, we highlight distinct application routes proven in downstream chemical and materials industries, emphasizing authentic process information and compliance with sector-specific regulations.

    1. Pharmaceutical API Intermediate Synthesis

    Pharmaceutical manufacturers use 2-Chloro-M-Cresol as a core intermediate during the synthesis of antibacterial and antifungal active pharmaceutical ingredients. Its ortho-chloro substitution pattern introduces desirable reactivity in specific heterocyclic compounds formation, such as for antimycotic agents, where controlled halogen content is critical to meet finished API quality. Strict quality control governs initial charge purity, and stagewise monitoring ensures reaction selectivity. Batch-to-batch reproducibility relies on precise millimole-level measurement at each condensation or alkylation process.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) for APIs
    • United States Pharmacopeia (USP) Monograph for related APIs
    • European Pharmacopoeia (Ph. Eur.) Intermediate Quality Guidelines
    • FDA 21 CFR Part 210/211 for finished pharmaceuticals

    Typical usage ratio

    • 0.5–2.0 molar equivalents depending on target API formation step
    • Adjusted based on stoichiometry and impurity control of condensation reactions

    Downstream process integration

    • Dosed directly into initial synthesis vessel during heterocyclic ring assembly
    • Reacted via nucleophilic substitution or coupling reactions under controlled temperature and pH
    • Purity confirmed by HPLC and NMR prior to next process transfer

    Final product types

    • Antifungal drug intermediates
    • Benzoxazole-based antimicrobial APIs
    • Chlorinated phenol-derived pharmaceutical compounds
    • Preservative agents for topical formulations

    2. Industrial Preservatives for Metalworking Fluids

    Metalworking fluid manufacturers incorporate 2-Chloro-M-Cresol as a biocidal preservative to inhibit bacterial and fungal contamination in water-miscible cutting oils and coolants. Its efficacy against gram-positive and gram-negative microorganisms fits stringent health and safety regulations, particularly where exposure to high humidity and organic debris accelerates spoilage. Process engineers select the dosing ratio through microbial challenge studies, balancing longevity with occupational safe limits.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 Biocidal Products Directive (BPD)
    • U.S. EPA FIFRA Listed Antimicrobial Use in Metalworking Fluids
    • ASTM E2169-13 Standard Guide for Microbicides in Aqueous Metalworking Fluids
    • OSHA Hazard Communication Standard for chemical safety

    Typical usage ratio

    • 0.05–0.15% w/w in concentrate formulations, adjusted per fluid matrix and performance testing
    • Final in-use concentration between 200–600 ppm

    Downstream process integration

    • Blended as a concentrate with emulsifiers, lubricants, and corrosion inhibitors
    • Added post-emulsification to prevent degradation by thermal or shear stress
    • Subjected to stability and compatibility testing as per end-user specification

    Final product types

    • Water-miscible metalworking fluids (coolants, cutting oils)
    • Milling and turning fluid concentrates
    • Hydraulic and lubricating fluid biocide packages
    • Maintenance cleaners for metalworking system sanitation

    3. Active Ingredient in Wood Preservation Formulations

    Wood protection solution manufacturers utilize 2-Chloro-M-Cresol as an active ingredient in preservative blends targeted at mold, fungi, and wood decay prevention. Its phenolic structure disrupts enzymatic degradation pathways in lignocellulosic substrates, delivering extended preservation under high moisture exposure. Compliance with national and international wood treatment regulations is mandatory, with finished formulation screening for leaching and long-term environmental profile.

    Industry compliance standards

    • AWPA P8 Standard for Oilborne Wood Preservatives
    • EN 599-1 Wood Preservatives – Performance against fungi and microorganisms
    • US EPA Pesticide Registration for wood preservatives
    • OECD 303A Biodegradability Testing for leachate assessment

    Typical usage ratio

    • 0.2–0.6% w/w in preservative concentrate, increased for tropical or exterior applications
    • Ratio based on wood species porosity and projected exposure category

    Downstream process integration

    • Mixed with carrier oils, fungicides, and dispersants before autoclave impregnation
    • Applied to timber products via vacuum-pressure or double-vacuum treatment
    • Post-treatment conditioning ensures toxin stabilization within timber matrix

    Final product types

    • Pressure-treated utility poles
    • Outdoor construction timber
    • Packaging and shipping pallets
    • Landscape and fencing lumber

    4. Specialty Dye and Pigment Manufacturing Intermediate

    Manufacturers of specialty dyes and industrial pigments leverage the phenolic and chloro functionalities of 2-Chloro-M-Cresol in the synthesis of azo and phthalocyanine colorants. Its incorporation facilitates chromophore development with targeted hue and fastness properties, essential for technical textile, ink, and polymer coloration. Production requires precise control of substitution and coupling steps, with downstream QC verifying washability and lightfastness in finished pigment applications.

    Industry compliance standards

    • ISO 105 Series: Textile Colorfastness Standards
    • EN 71-3:2019 Safety of Toys – Migration of certain elements (pigments in toys and inks)
    • ETAD Code of Practice for Responsible Dye Manufacturing
    • REACH Annex XVII: Restrictions on use in consumer products

    Typical usage ratio

    • 0.1–0.8 equivalents per colorant synthesis, tailored by target chromophore structure
    • Precise adjustment in multi-step azo or phthalocyanine pigment syntheses

    Downstream process integration

    • Introduced as a starting phenol for diazotization or direct coupling reactions
    • Combined with nitro/aromatic amines, followed by coupling to generate final dye molecule
    • Isolated intermediates purified by recrystallization prior to pigment milling

    Final product types

    • Industrial textile dyes (acid/azo dyes)
    • Specialty printing ink colorants
    • Polymer-compatible pigment dispersions
    • Leather finishing agents
    Free Quote

    Competitive 2-Chloro-M-Cresol prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

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    Certification & Compliance
    More Introduction

    2-Chloro-M-Cresol: Real-World Insights from a Chemical Manufacturer

    Precision Chemistry Meets Practical Application

    Out here at our plant, 2-Chloro-M-Cresol has become a mainstay in our lineup for good reasons. Unlike generic cresols, this compound, also known as 3-chloro-5-methylphenol, brings a unique blend of reactivity and stability. Our process fine-tunes every stage, starting from raw material selection to the final purification, to produce a chemical that performs with consistency. When clients receive their shipment, they’re not rolling the dice—they’re getting a material built for reliability and measured to spec every time. We run our batches for tight control on impurity levels, aiming for purity above 99%, which directly influences product performance downstream.

    Clear Model, Reliable Specifications

    We produce 2-Chloro-M-Cresol under a process model that’s been refined by hands-on chemists and engineers. Our crystalline powder comes off the reactor with a white to pale yellow appearance. Typical melting point sits close to 63°C, a signature trait helping formulators keep control over their own production parameters without unexpected flux. Moisture content and heavy metal levels stay well within the safe range, confirmed by direct lab analysis batch after batch. Flash point checks and GC purity tests go beyond paperwork for us—they’re part of the daily rhythm.

    How 2-Chloro-M-Cresol Earns Its Spot in Manufacturing

    Every user arrives at this compound for different reasons. One finds in it a strong antimicrobial punch, using it as a preservative in disinfectants and antiseptics. Another likes its efficiency as an intermediate for pharmaceutical synthesis. Some come from the dye sector, chasing its chemical backbone for producing specific pigments. A handful turn to its proven track record in agrochemical preparations, benefiting from its reactivity and relative shelf stability. Unlike some less stable isomers, this molecule doesn’t give off stubborn odors nor does it readily degrade in reasonable storage conditions. We see demand from markets where tight regulatory oversight means no leeway for off-quality materials, so we keep our spec sheet short, clear, and never window-dressed.

    Real Challenges, Real Solutions

    We’ve watched enough batches run to know the little problems can become big ones in this chemistry. Traces of unwanted phenolics can throw off antimicrobial efficacy or create hurdles when a downstream user tries to hit regulatory thresholds. Slight discoloration might not matter to everyone, but if your end product is a transparent liquid or a light cream, these aesthetic shifts become unacceptable. Our labs catch these before shipments ever leave, tweaking process variables or adding another recrystallization if the lot strays.

    Handling 2-Chloro-M-Cresol also gets practical attention. That means closed systems, direct venting, and grade-specific packaging that doesn’t absorb or transfer the product’s scent—no off-flavors, no residue. The crystalline nature of our product makes measuring and handling straightforward. Users in the field report easier integration and less clumping or caking compared to lower-grade materials. That keeps downstream lines running, formulas balanced, and finished products stable during storage.

    Comparing 2-Chloro-M-Cresol to Other Cresols

    Our history includes runs with plain m-cresol and other chloro-cresol isomers. 2-Chloro-M-Cresol stands apart in antimicrobial uses, as its chlorination at the meta position tunes efficiency without the harshness or volatility of the ortho form. Where o-chloro-cresol sometimes contributes a pungent note or causes compatibility headaches in emulsions, the meta isomer plays well with a wide array of solvents and excipients. We’ve seen formulators in the personal care industry gravitate toward this compound for that reason. Traditional cresols call for careful odor-masking strategies, but the 2-chloro variant tends not to interfere with delicate fragrance blends.

    Compared to p-chloro-m-cresol, often aimed at similar sectors, 2-chloro’s profile offers a more balanced compromise between reactivity and handling safety. Some clients balance raw material ordering based on price swings; we’ve learned through experience that switching between these isomers just for cost savings can backfire due to differences in solubility, volatility, or risk assessments. User feedback directly influenced our decision to standardize on 2-Chloro-M-Cresol as a core product—performance and predictability won out over penny-pinching.

    End-User Confidence and Transparency

    Trust isn’t built on slogans; it grows with shared results. Our buyers don’t just receive bags or drums—they get a batch ticket with full traceability including melting point, purity, moisture, and color confirmation. Phone calls and field visits matter when someone reports a concern. One year, a customer in the hospital disinfectant field noticed a color drift in their finished blend after a raw material switch from another supplier. Our product didn’t just beat the test; it solved the cosmetic issue outright. Instances like that come from consistency in plant practices, not shortcuts.

    We field questions about potential nitrosamine formation or residual solvents. Thanks to our direct involvement in every production step, we’ve refined the process to keep unwanted side products well below global limits. We use only approved solvents for synthesis and offer documentation on residual content measured against current ICH guidelines. Not every manufacturer can speak directly about how every raw material and auxiliary used at each stage affects the overall impurity profile—but we can, because we own and control the route from start to finish.

    Versatility Out in the World

    Some formulators run 2-Chloro-M-Cresol in surface disinfectants for public transit systems. Its broad-spectrum control over bacteria, fungi, and even certain viruses meets the regulatory bar without extra blending or pH adjustment. Others leverage it as a coupling agent in dye intermediates, timing its reactivity to achieve consistent yield and brightness. Veterinary products tap into its stable performance; shelf life runs long, and the compound resists breakdown during autoclave cycles or varying warehouse conditions.

    Paint and coatings specialists have reported its value in selective biocidal applications, where it outlasts conventional preservatives under damp storage conditions. Feedback from these industries pushes us to update our analytical tests and shipping practices to match how clients really use the product, rather than relying on textbook handling rules. We’ve reworked packaging designs for dust control in line with feedback from operators who stock hundreds of kilograms at a time.

    Addressing Potential Risks with Expertise

    Not every chemical is as forgiving as it looks on paper. We’ve seen new operators underestimate the irritation risks of cresol vapors. Our response was to develop tailored safety data sheets and hands-on training modules that reflect what happens in a real production line, updating recommendations as we learn more from field reports. Investing in accurate detection methods for air and surface contamination allows our clients to improve worker safety while avoiding unnecessary shutdowns.

    We partner with downstream users to monitor cumulative exposure—especially in high-throughput pharmaceutical and personal care lines where workers come in regular contact with base chemicals and intermediates. Routine audits of dust and vapor emissions have reduced lost-time incidents and built goodwill with local regulators. We’ve also set up buffer programs to help small and mid-sized users transition to automated handling, eliminating unnecessary manual steps without jacking up costs.

    Sustainability and Process Evolution

    Cost isn’t the only lens for evaluating chemicals. We continually revisit raw material sourcing to reduce waste, cut emissions, and improve yield. Recent upgrades led to recycling a fraction of the process solvents, dropping both costs and the plant’s overall footprint. Long-term relationships with upstream suppliers help us document provenance and minimize the chance of foreign residues or accidental contamination.

    Our waste treatment system was rebuilt based on feedback from peer networks and client concerns over visible discharge or odor near the plant. We saw an uptick in auditing requests from global clients; robust documentation and open plant visits quieted most worries. Users in regions with stricter discharge rules now rely on us for support in navigating compliance. We pass along best practices we’ve learned for handling washing waters, spent quench solutions, and drum cleanup, saving clients from repeating our growing pains.

    Collaboration and Continuous Improvement

    We never operate in a vacuum. Our production and QC teams regularly visit client sites to watch how real people interact with our product in the wild. These field trips spotlight subtleties that lab work alone can never fully simulate—like the effect of climate on storage, or how a blender operator controls dust with a particular scoop technique. We fold these insights into both manufacturing and technical support so every batch delivers more value than just chemical composition.

    Feedback loops result in real-world improvements. Examples include tighter spec controls after a large disinfectant producer documented issues during the monsoon; changes in process water treatment after an agrochemical blender traced a shelf-life drop to micro-level chloride uptake. Our technical service teams build relationships, not just checklists—they talk shop and trouble-shoot in real time with client process engineers. This builds a kind of peer trust rare in the chemical trade.

    Why 2-Chloro-M-Cresol Earns Repeat Business

    Most of our repeat clients didn’t come back because of glossy brochures or lowball pricing. They come back after seeing what consistent quality and open lines of communication can do for their bottom line. When a process batch goes right because the spec doesn’t drift or a regulatory inspection is passed without surprises, the relationship grows. Price matters, but predictable performance and practical support carry more weight with those who know the cost of downtime or failed batches.

    We encourage clients to use our lot testing as part of their own incoming QA. We offer second-sample archiving, open-book process overviews, and rapid-turnaround troubleshooting as part of every shipment. Transparency isn’t negotiable; we back every claim with hard data, not just a certificate.

    Looking Ahead: Adapting to Change

    Markets shift, customer requirements evolve, and new regulations emerge across industries where 2-Chloro-M-Cresol plays a crucial role. We don’t treat change as a threat, but rather as a prompt to revisit old assumptions, invest in better analytics, and stretch technical creativity. Fields like pharmaceutical synthesis demand ongoing adaptation, especially with new patient safety standards. Disinfectant formulators face pressure to deliver both broad-spectrum action and environmental acceptability. This feeds directly into our R&D investments—whether that means tuning impurity spec, trialing greener routes, or updating our handling manuals.

    Sourcing remains a core concern as political and economic tensions swirl globally. We keep supply chain risks front and center, holding extra stock and diversifying secondary vendor certifications. Our partners count on getting the right product at the right spec, on the right schedule. Lessons from the COVID-19 disruptions taught us that robust logistics planning can offset nearly any shipping slowdown or border hiccup.

    How We Support Innovation at Every Stage

    We value open dialogue from first inquiry to ongoing technical review. Our team members—plant operators, chemists, and QA managers—routinely take user input back to the shop floor, where it matters most. We’ve built new process controls in direct response to client-driven challenges, from dust mitigation on the filling line to tighter traceability for audits in the pharma and personal care sectors. No investment substitutes for real-world feedback or the firsthand problem-solving that comes from walking a line or troubleshooting at a client’s site.

    While many chemicals play background roles, 2-Chloro-M-Cresol brings value where performance, safety, and consistency overlap. Direct manufacturing experience puts us in a place to make claims backed by traceable data, honest field tests, and transparent dialogue. Our willingness to share insights, listen, and adjust not only retains business—it elevates partnership beyond commodity trading. We see the results in fewer batch failures, swifter compliance checks, and higher satisfaction throughout our client community.

    Conclusion: Real Value in Real Partnerships

    After years working hands-on with 2-Chloro-M-Cresol, our view focuses on doing right by the people using this compound in the field. Consistency and a down-to-earth approach let our clients build better products, reduce risks, and navigate industry shifts with fewer surprises. We don’t promise perfection, but we never stop short of honest data, clear support, or continual process improvement. This process-driven, responsive way of working defines who we are—not just as suppliers, but as genuine partners in growth and quality.