Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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2-Butyne

    • Product Name 2-Butyne
    • Alias Dimethylacetylene
    • Einecs 207-334-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    259468

    chemical_name 2-Butyne
    cas_number 503-17-3
    molecular_formula C4H6
    molar_mass 54.09 g/mol
    appearance Colorless gas
    boiling_point 27 °C
    melting_point -76 °C
    density 0.681 g/cm³ (at 25 °C)
    flash_point -36 °C
    solubility_in_water Insoluble
    iupac_name But-2-yne
    pubchem_cid 7849
    structure CH3C≡CCH3
    vapor_pressure 450 mmHg (at 20 °C)
    flammability Highly flammable

    As an accredited 2-Butyne factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 2-Butyne is supplied in a 1-liter high-pressure steel cylinder with secure valve, labeled with hazard warnings and handling instructions.
    Shipping 2-Butyne is shipped as a flammable compressed gas in high-pressure cylinders or tanks. It must be handled and transported under strict safety regulations, avoiding heat, open flames, and strong oxidizers. Shipping containers must be clearly labeled, and ventilation is required to prevent hazardous vapor accumulation during transit.
    Storage 2-Butyne should be stored in a cool, well-ventilated area, away from sources of ignition or heat, as it is highly flammable. Keep it in tightly closed, properly labeled containers made of compatible materials. Protect from sunlight, moisture, and oxidizing agents. Use approved gas cylinders if stored as a compressed gas, and ensure proper grounding to prevent static discharge.
    Application of 2-Butyne

    Applications of 2-Butyne in Industrial Manufacturing

    2-Butyne, a linear alkyne hydrocarbon, serves as a specialized intermediate in multiple industrial processes. As a manufacturer, we focus on well-established downstream segments based on proven application data and real production requirements.

    1. Synthesis of Pharmaceuticals (API Intermediate)

    2-Butyne functions as a key building block in active pharmaceutical ingredient (API) synthesis, especially for compounds needing terminal or internal alkynes. During hydrogenation, halogenation, or coupling, it enables molecular frameworks that underpin various antiviral and anticancer agents. Its reactivity in Sonogashira and Cadiot-Chodkiewicz couplings supports fine-tuned API manufacturing where consistency and purity drive GMP compliance.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for APIs)
    • USP/NF (United States Pharmacopeia/National Formulary)
    • European Pharmacopoeia (Ph. Eur.)
    • China Pharmacopoeia (ChP)

    Typical usage ratio

    • Ranges from 0.8–1.4 mole equivalents, adjusted by process scale and target reaction yield. Ratio depends on API synthetic pathway and byproduct minimization.

    Downstream process integration

    • Direct charging into batch or continuous reactors during early or middle API synthesis
    • Fed-batch input for coupling reactions under inert atmosphere
    • Integration with hydrogenation lines for conversion to butenes or secondary alcohol intermediates

    Final product types

    • Antiviral and oncology APIs (e.g., containing alkynyl fragments)
    • Intermediates for cardiovascular drugs
    • Research compounds for medicinal chemistry

    2. Polymer Modifier in Specialty Rubber Manufacturing

    Industrial rubber producers use 2-Butyne as a functional monomer or chain modifier, especially in making nitrile and acrylonitrile-butadiene rubbers. Its triple bond improves crosslink density and modifies mechanical properties such as tensile strength, processing temperature, and resistance to heat aging. Optimizing addition timing and concentration is vital to prevent gelation and control molecular weight.

    Industry compliance standards

    • ISO 9001:2015 (Quality Systems in Polymer Production)
    • ASTM D3182 (Mixing and Vulcanization)
    • EU REACH (Regulation EC 1907/2006)
    • Japanese Industrial Standards (JIS K 6320 for rubber)

    Typical usage ratio

    • 0.01–0.5% by mass, tuned according to desired polymer chain length and mechanical property profile

    Downstream process integration

    • Co-feeding with butadiene or acrylonitrile latex streams during polymerization
    • Added before or during emulsification to functionalize backbone structure
    • Reactive blending for high-performance elastomer applications

    Final product types

    • Oil-resistant rubber gaskets
    • Specialty hoses and belts
    • Automotive and aerospace polymer components

    3. Fine Chemical Synthesis (Agrochemical Intermediates)

    2-Butyne appears in the synthesis of regulated agrochemicals, especially as a precursor for propargylic or acetylenic intermediates in herbicide and insecticide production. It facilitates additions and cyclizations that create unique molecular architectures. Reaction parameters must support compliance with downstream product registrations and residue requirements.

    Industry compliance standards

    • FAO/WHO Specifications for Pesticides
    • OECD Principles of Good Laboratory Practice
    • ISO 17025 (Testing and Calibration for Agrochemicals)
    • China ICAMA registration (for agricultural chemicals)

    Typical usage ratio

    • 0.03–1.2 molar equivalents depending on reaction specificity and conversion efficiency requirements

    Downstream process integration

    • Dosed as primary reactant in closed vessel alkynylation reactions
    • Introduced pre-purification stage for synthesis steps requiring high acetylenic purity
    • Purge and recovery protocols integrated to control volatile organic emissions

    Final product types

    • Pre-emergent herbicide actives
    • Acetylenic insecticides and fungicides
    • Plant growth regulator intermediates

    4. Gas-Phase Alkylation and Dehydrogenation Catalyst Feedstock

    Major chemical producers deploy 2-Butyne as a feedstock in selective alkylation or dehydrogenation, where it enhances yield of C4 and C5 olefins. Careful process control in fixed-bed or fluidized-bed reactors prevents coking and enables integration with unit operations for separating methylbutenes. The compound's reactivity must match catalyst activity profiles and regeneration intervals for economic operation.

    Industry compliance standards

    • API Standard 560 (Fired Heaters for Refineries)
    • ASME BPVC Section VIII (Pressure Vessels)
    • OSHA 29 CFR 1910.119 (Process Safety Management)
    • Responsible Care (International Council of Chemical Associations)

    Typical usage ratio

    • Feedstock concentration 2–5% molar in combined hydrocarbon stream, adjusted for plant size and catalyst performance targets

    Downstream process integration

    • Pumped via manifold pipes directly into alkylation reactors under continuous flow regime
    • Integrated online with product gas analysis for yield monitoring
    • Linked to distillation columns for real-time separation of olefin products

    Final product types

    • Methylbutene isomers and pentene derivatives
    • High-octane blending components for gasoline
    • Feedstock for specialty monomers in polymer chains

    5. Synthesis of Specialty Solvents and Electronic Chemicals

    2-Butyne serves as a precursor for high-purity solvent manufacture, crucial in electronic-grade and semiconductor processing. Through selective hydrogenation or oxidation, it leads to butanediol, ethers, or specialty alcohols necessary for microfabrication, photoresist formulation, or cleaning processes. Control over trace impurities and quality assurance aligns with strict downstream purity audits and lot-traceability requirements.

    Industry compliance standards

    • SEMI C27 (Grade for Electronic Chemicals)
    • ISO 14644 (Cleanroom Requirements)
    • RoHS Directive (2011/65/EU)
    • Quality system audits per IATF 16949 (Automotive Electronics)

    Typical usage ratio

    • Feed input from 0.5–3.5% w/w in multi-stage synthesis blends, based on solvent grade and final use specification

    Downstream process integration

    • Charged as feedstock in catalytic hydrogenation units
    • Introduced to reactor train with in-line solvent purification and monitoring
    • Transferred to final distillation or blending with stabilizing agents

    Final product types

    • Ultra-high purity 1,4-butanediol
    • Electronic cleaning solvents
    • Photoresist developer base fluids
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    Certification & Compliance
    More Introduction

    2-Butyne: Inside the Production and Real-World Uses

    Introduction to 2-Butyne from the Source

    Every day in our chemical plant, we work with 2-Butyne — a colorless, flammable gas. It is sometimes called dimethylacetylene by chemists, but among our crew it’s known simply as “2-Butyne.” We manufacture it under strict conditions, using reliable feedstocks and routine batch verification, because experience has taught us that even small variances can change the outcome at the next step of a process. At the core, our focus is on maintaining a standard that the labs and industrial teams can trust, with little deviation batch to batch.

    The model we supply regularly is 2-Butyne with a purity exceeding 99%. The vapor pressure, density, and boiling point have all been measured countless times here by our team, and every batch is checked for residual moisture and the presence of common byproducts like 1-Butyne or methylacetylene. While those names sound similar, the minor differences in their chemical structure really matter during synthesis or actual use. Manufacturing 2-Butyne means working with tight equipment tolerances; even a slight pressure shift during separation will tip off our monitoring system, and process engineers don’t ignore those alarms.

    Daily Use in Synthesis and Industry

    2-Butyne’s appeal comes from its unique properties as an alkyne. The triple bond makes it reactive with several catalysts, so it fits well in specialty syntheses. Over years in the plant, we’ve watched customers use it mostly as an intermediate, especially when they need carbon-carbon coupling or a clean syn addition. We send most drums to organic chemists in the pharmaceutical and agricultural sectors. If you’ve worked through a Grignard reaction or a transition-metal catalyzed cross-coupling, there’s a good chance someone on our floor helped craft that key intermediate.

    We notice that 2-Butyne is chosen for its selectivity in research projects and pilot plants. In our own post-synthesis analysis, the higher electron density at the triple bond leads to fewer byproducts when compared to some other alkynes. Manufacturing teams prefer this because it cuts down on waste and the need for costly purification. Most requests for increased purity come from researchers pushing new frontiers, who need every bit of reproducibility and consistency they can get.

    Our longtime partners in the semiconductor field use 2-Butyne as a carbon feedstock for some CVD processes. They appreciate the gaseous form and volatility for surface treatments. The gas flows cleanly and decomposes predictably, so layers form with less risk of impurities or unwanted deposits. In these high-precision spaces, any deviation in the gas stream composition can cause headaches weeks down the line, so our team works directly with their process managers to align collection and trans-shipment schedules.

    Differences from Other Similar Alkynes

    With so many chemical options available, clients occasionally ask about the difference between 2-Butyne and isomers like 1-Butyne or methylacetylene. From our experience, these differences matter. In 2-Butyne, both triple-bonded carbons sit in the middle of the chain. This seemingly small shift changes reactivity, boiling point, and even handling requirements. 1-Butyne, as its name suggests, places the triple bond at the end of the chain, opening up the possibility for very different side reactions. Our reactors are finicky enough to remind us often how a small isomer position will disrupt a catalyst, raise a thermal runaway risk, or lead to blocked pipelines. That simple shift from terminal to internal triple bond is not just theory to us — it’s what keeps our alarms quiet.

    We avoid mixing streams of 2-Butyne and 1-Butyne for this reason. If our reaction vessel receives the wrong isomer, the chemistry may stall or give unwanted products. 2-Butyne also behaves differently on storage, where the vapor pressure remains slightly lower than methylacetylene under the same temperature and tank setup. These differences come from how the molecule distributes its electrons and, over time, we’ve learned this knowledge pays off in more streamlined operations.

    Users sometimes compare 2-Butyne to acetylene, another alkyne, but it’s not a simple substitute. Acetylene’s terminal bond, instability under pressure, and greater reactivity make it prone to decomposition unless carefully stabilized. Even the smallest contaminants or improper cylinder handling have led to costly downtime for end users. In contrast, 2-Butyne offers a steadier experience for many synthesis reactions — especially where selectivity and control outweigh pure reactivity.

    Handling the Real-World Challenges

    Plant experience has taught us not to underestimate 2-Butyne — it rewards vigilance and tight inventory controls. On any production line, leaks or vapors must be contained, not only because losses mean lost revenue, but also because this compound flashes at low energy and quickly vaporizes in air. We keep our tanks shielded, with redundant monitoring and continuous improvement schemes in place. Periodic audits dig into every shutoff switch, pressure relief valve, and sampling port. The challenge is not just making the compound, but ensuring it ships in a form our customers can actually use — without risk, without delay, and with a clear record of every hand that touched it.

    Transporting 2-Butyne has always required more than paperwork. We believe in close coordination with haulers, from pickup at our central dock to final delivery to a customer’s lab or process tank. Smaller customers sometimes ask if they can refill partial cylinders, but from experience, we recommend against it — every transfer can introduce air or contaminants that degrade the batch. Our standard response is to send single-use, pre-checked vessels when purity or trace analysis matters most. Batch-to-batch recall reports are available directly from our quality team, reducing hassle in any regulatory review or troubleshooting situation.

    Storage presents more day-to-day challenges than outsiders usually realize. Each gas cylinder must be checked regularly for corrosion, and our engineers often step in to refine storage protocols, especially for large-volume installations. Ambient temperature swings will affect vapor pressure inside a tank, and plant staff react quickly to unexpected shifts. We send field teams to help with on-site sorting or emergency offloading if someone’s monitoring system triggers an alarm. Direct support keeps supply lines open, builds trust, and gives us feedback that leads to process changes at our main site.

    Why Reliable Manufacturing Matters

    The success of our 2-Butyne comes from an approach that prioritizes stability over speed. We’ve seen competitors cut corners on purification and analytics, sometimes leading to interrupted runs or failed syntheses downstream. Our own data shows that investing in continuous batch monitoring cuts customer complaints and late-night repair requests dramatically. We spare no effort in routine maintenance; predictive analytics help us spot wear on column packing, detect out-of-spec feedstocks, or predict when a tank valve risks failure.

    We’ve also learned the importance of transparency. Our customers call directly about test data, run histories, and even production logs. The trust we build by opening our records helps universities gain regulatory approval for grant work and supports pharmaceutical projects working on new therapies. We make our purity certificates detailed, not just for compliance, but because every decimal point helps the next person make the right process tweak.

    For newer clients, we offer insights into unexpected quirks during the first weeks of operation. Some solvents extract 2-Butyne more efficiently, but others need extra agitation or chilling to keep losses minimal. Handling larger volumes in high-throughput reactors sometimes requires ground-level plant modifications to vent, chill, and recycle excess vapors. Any questions about scale-up get routed directly to our technical services group; no one wants to be caught off guard, especially when handling an alkyne.

    Innovation and Sustainability in the Field

    The real draw for clients working with new green chemistry projects is the flexibility 2-Butyne brings. Our years of feedback from R&D teams have shown us that innovation rarely follows a straight line. In catalysis labs, 2-Butyne offers alternative reaction routes, sometimes allowing for solvent-free processes or milder conditions. Solutions that work with 2-Butyne can reduce the amount of hazardous waste compared to some older synthetic methods. This environmental angle matters more with each passing year, as customers face tighter waste regulations and rising disposal costs.

    Our own process chemists frequently review literature to adapt new purification steps or analytic controls. We have tested small-scale solvent recoveries, membrane separations, and even explored renewable feedstocks for pilot runs of 2-Butyne. Some of these methods have made their way into regular production sequences, reducing solvent demand by a measurable amount. While change is never simple for an established manufacturing site, the efficiency gains support both our own business and our customers’ sustainability goals.

    Our partnerships with industry and academia have grown partly because we don’t wait for regulations before adjusting formulations or testing new packaging. We sponsor research into safer, smaller gas cylinders for critical laboratory work, including improved regulators and intelligent venting systems. Shared lessons from incidents in the field let us anticipate issues that others may still be catching up to — no one likes to lose a batch because of a valve failure or incorrectly cleaned drum.

    Compliance and Documentation in the Modern Chemical Industry

    Working as a direct producer, we’re responsible for documentation covering every aspect of 2-Butyne’s life. Traceability stands out as a routine demand, not only from regulators but from any customer with audits tied to good manufacturing practice or international standards. We log every raw material lot, production step, analytic checkpoint, and shipment, keeping digital records cross-referenced and accessible on request.

    This careful recordkeeping has saved clients significant time during inspections. When laboratories or pilot plants face sudden recalls or spot-checks, we can furnish purity data, MSDS records, and full batch histories without delay. Our analytic reports include detection limits for all typical byproducts and impurities, along with full chromatographic traces to satisfy skeptical investigators. Feedback from customers has led us to refine our reporting process, making it easier for teams working on tight product launch schedules or with multiple regulatory bodies.

    Engagement with regulators goes deeper than paperwork. Our safety engineers work closely with national and regional bodies, helping shape safety and storage guidelines based on practical experience. When new shipping standards emerge for compressed gases, we adjust our supply lines, retrain shipping teams, and phase in compliant cylinder types well before deadlines loom. This level of preparation benefits customers and keeps costly delays from interrupting steady supply.

    Real-World Impact Through Customer Connections

    Stories from plant managers, chemists, and researchers using 2-Butyne have given us perspective on its everyday importance. In one recent research collaboration, a university team tested catalytic routes to fine chemicals, and minor changes to our purity specifications made the difference between reproducible yields and a string of failed runs. Working through issues like this in partnership, with open engineering logs and shared analytic results, shortens turnaround and lets new discoveries reach the market faster.

    For large-volume users in the electronics field, our regular feedback loops on gas quality have helped reduce downtime. Achieving critical layer uniformity in vapor deposition depends not just on chemical composition, but on physical consistency. By tuning our cylinder pressures and shipment scheduling to their needs, we help protect multi-million-dollar production investments.

    Sometimes, small startups and academic labs reach out with questions about first-time use — setting up regulators, tracking losses from venting, or connecting to microreactors. We make a habit of supplying practical guides, troubleshooting assistance, and on-call technical advisors. This direct channel not only builds loyalty, it brings back field observations that guide future product improvements and practical safeguard recommendations.

    Continuous Improvement and Leadership in Chemical Manufacturing

    Manufacturing 2-Butyne at a consistently high standard didn’t happen overnight. Our team has spent years mapping out every weak point in the supply chain, from feedstock selection to post-shipment cylinder tracking. We invest in analytics equipment, technician training, and hazard simulations — knowing that reliability pays off for everyone along the value chain. Equipment upgrades, lean process adjustments, and monthly staff safety reviews form the backbone of our ongoing improvement programs.

    Feedback from users has pointed to several shifts in 2-Butyne applications, especially the rise of selective catalysis and modern materials science. We stay agile, offering customization for volume, purity, and delivery method. Close ties with suppliers ensure that every incoming lot of feedstock meets strict internal benchmarks, blocking sources of unwanted trace impurities.

    Direct input from end users shapes our response to customer pain points. Rapid delivery for emergency restarts, custom batch documentation, and troubleshooting for field-scale reactors are daily business for our team. Building that relationship on technical accuracy and dependable logistics keeps projects running, research moving forward, and industrial sites humming along with fewer unexpected stops.

    Conclusion: The Value of Practical Expertise

    In the world of specialty alkyne production and application, details matter. At every turn, from plant floor to final user, our job is to keep risks minimal and performance consistently high. Years of direct chemical manufacturing experience drive an approach rooted in hands-on expertise, routine technical review, and a commitment to customer success. Working together with engineers, scientists, and technical managers, we keep finding ways to make 2-Butyne safer, cleaner, and more fit for purpose — supporting new discoveries and efficient production across industries.