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2-Butenal

    • Product Name 2-Butenal
    • Alias crotonaldehyde
    • Einecs 200-621-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    290330

    name 2-Butenal
    chemical_formula C4H6O
    molecular_weight 70.09 g/mol
    cas_number 4170-30-3
    appearance Colorless to light yellow liquid
    boiling_point 75-76 °C
    melting_point -81 °C
    density 0.845 g/cm³
    solubility_in_water Miscible
    flash_point 1 °C
    refractive_index 1.419
    iupac_name but-2-enal
    pubchem_cid 7855

    As an accredited 2-Butenal factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 2-Butenal is packaged in a 500 mL amber glass bottle with a secure screw cap, labeled with hazard symbols and handling instructions.
    Shipping 2-Butenal (crotonaldehyde) should be shipped in tightly sealed containers, away from heat, sparks, and oxidizing agents. It must be labeled as a flammable and toxic liquid, following all applicable hazardous material regulations. Proper ventilation and secondary containment are recommended to prevent leaks during transit, and emergency response information should accompany the shipment.
    Storage 2-Butenal should be stored in a cool, dry, and well-ventilated area, away from heat, sparks, or open flames. Keep containers tightly closed and protected from light. Store separately from oxidizing agents, acids, and bases. Use explosion-proof electrical equipment and grounding methods. Ensure proper labeling and restrict access to trained personnel only. Avoid prolonged storage to minimize polymerization and decomposition risks.
    Application of 2-Butenal

    Applications of 2-Butenal in Industrial Manufacturing

    As a specialized producer, we support industrial partners with high-purity 2-Butenal for advanced manufacturing processes. Our applications section outlines verified scenarios where 2-Butenal is directly incorporated as a key raw material in downstream value chains. Each segment below details exclusive industry standards, formula ratios, integration steps, and tangible end products established in operational environments.

    1. Pharmaceutical Intermediates: Synthesis of Active Pharmaceutical Ingredients

    2-Butenal functions as a core building block in several pharmaceutical synthesis routes, notably for creating intermediates in antihypertensive and antimicrobial APIs. Its reactive unsaturated aldehyde structure makes it valuable in aldol-type condensations, underpinning regulated production of select active ingredients. Formulators precisely dose 2-Butenal during the intermediate step to ensure quality control and compliance, while downstream process data is tightly integrated for batch record traceability and regulatory submission.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for APIs
    • US Pharmacopeia (USP) guidelines pertaining to impurity profiles
    • European Pharmacopoeia (Ph. Eur.) monographs for relevant APIs
    • FDA 21 CFR Part 211 – Current Good Manufacturing Practice (cGMP) for Finished Pharmaceuticals

    Typical usage ratio

    • 5–20 mol% relative to total reactants in pharmaceutical synthesis; selected ratio based on desired intermediate yield and purity requirements

    Downstream process integration

    • Introduced during the key condensation stage of API intermediate synthesis; addition time and temperature tightly regulated as per validated SOPs

    Final product types

    • Antibiotic active pharmaceutical ingredients (e.g. β-lactams precursor)
    • Antihypertensive agents (e.g. ACE inhibitor intermediates)
    • Synthetic intermediates for anti-infective drugs
    • Homologation intermediates in cardiovascular medication production

    2. Agrochemical Synthesis: Manufacture of Pesticide Precursors

    2-Butenal serves as a principal carbonyl compound in chemical transformations leading to various pesticide active ingredients and their precursors. In large-scale agrochemical facilities, technicians employ 2-Butenal in enantioselective routes, optimizing reaction sequences to meet global registration standards for crop protection. Quality assurance teams monitor formulation ratios and residual levels to comply with established regulatory maximums in finished pesticide actives.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • OECD Guidelines for the Testing of Chemicals (for pesticide ingredients)
    • ISO 9001:2015 for Quality Management in Agrochemical Production
    • China GB/T 1604 standards for pesticide raw material quality

    Typical usage ratio

    • 8–18% by weight in precursor synthesis stages; formulators calibrate based on crop target and regulatory residue limits

    Downstream process integration

    • Loaded into agitated reactors during the controlled alkylation or cyclization step leading to pesticide base structures, with batch analytics ensuring conversion and absence of unreacted aldehyde

    Final product types

    • Herbicide precursors for amide and keto-herbicide families
    • Insecticide intermediates (e.g. for neonicotinoid precursors)
    • Fungicidal actives manufactured via heterocyclic condensation
    • Growth regulator base molecules

    3. Flavor & Fragrance Ingredient Production

    2-Butenal brings a distinct unsaturated aldehyde note, contributing character to specialty flavor bases and certain fragrance aldehydes. Major compounding operations in the flavor and fragrance sector use this material in closely controlled micro-dosing as a reaction component in natural-identical aroma synthesis. Robust documentation and batch traceability ensure full compliance with regional and international additive regulations, particularly where downstream applications enter the human food or personal care supply chain.

    Industry compliance standards

    • FCC (Food Chemicals Codex) purity specifications for flavor ingredients
    • EU Regulation (EC) No 1334/2008 on flavorings and certain food ingredients
    • IFRA Standards for fragrance safety and allowable aldehyde use levels
    • US FEMA GRAS assessment for flavor ingredient acceptance

    Typical usage ratio

    • 0.02–0.20% by weight in finished flavor and fragrance batches; dosage defined by sensory impact, toxicological thresholds, and end-application exposure caps

    Downstream process integration

    • Added during stepwise blending in the compounding stage; often reacted with other aldehydes and alcohols to develop target flavor or aromatic notes; process incorporates in-line monitoring of volatile concentrations

    Final product types

    • Baked goods flavor concentrates (e.g. croissant, caramel top-notes)
    • Fragrance aldehyde bases for fine perfumes (e.g. woody-aldehydic accords)
    • Dairy and savory flavor emulsions for processed foods
    • Toiletries and soap fragrances with aldehydic freshness

    4. Fine Chemicals: Synthesis of Specialty Alcohols and Ketones

    In fine chemical manufacturing, 2-Butenal acts as an intermediate for producing specialty alcohols (e.g., 1,3-butanediol) and ketones via hydrogenation or aldol addition. Its use is crucial in routes where precise double-bond placement and aldehyde functions drive downstream molecular construction. Quality teams anchor each batch to standard operating procedures validated by international chemical quality benchmarks, maintaining consistent feeding ratios and capturing conversion rates at each stage.

    Industry compliance standards

    • ISO 9001:2015 Quality Management for Fine Chemical Manufacturing
    • REACH Registration, Evaluation, and Authorization of Chemicals (EU)
    • JIS K1557 standard for organic chemical purity (Japan)
    • Responsible Care Global Charter for safe chemical management

    Typical usage ratio

    • 12–25% by mass in precursor charge, depending on desired yield and downstream reduction step parameters

    Downstream process integration

    • Feeds continuously or batchwise into fixed-bed hydrogenation reactors or, in aldol processes, combined with alcohols under basic conditions for ketone production; monitored for aldehyde consumption and side product minimization

    Final product types

    • 1,3-Butanediol for polymer and cosmetic ingredient markets
    • 4-Hydroxy-2-butanone as a specialty solvent
    • Fine chemical ketone intermediates supplied to aroma and electronics sectors
    • Chain-extended alcohols for plasticizer formulations

    5. Polymer and Resin Manufacturing: Chain-Transfer and Cross-Linking Agent

    In select resin and functional polymer chains, 2-Butenal takes on a role as a chain transfer or cross-linking agent, particularly benefiting copolymer modifications where controlled molecular structure influences mechanical and thermal properties. Integration into polymerization occurs under monitored conditions that balance reaction efficiency with product safety, following stringent compliance reviews for use in specialty resins.

    Industry compliance standards

    • ASTM D3983 for Aldehyde-Functional Monomer Quality
    • ISO 9001 for Polymeric Process Quality Controls
    • 2011/65/EU RoHS Directive (for electronics-related resins)
    • UL 94 Flammability Standards (for downstream polymer products)

    Typical usage ratio

    • 0.3–2.5% by weight of the total monomer charge, with adjustments suited to the degree of cross-linking or chain transfer required in downstream resin formulation

    Downstream process integration

    • Injected during pre-polymerization under controlled pH and temperature, facilitating branching or functional cross-link points within acrylic, vinyl, or styrene resin matrices

    Final product types

    • Acrylic impact modifiers for high-performance plastics
    • Specialty resins for adhesives and automotive coatings
    • Functionalized polymers for electronics encapsulation
    • Cross-linked copolymers used in 3D printed applications
    Free Quote

    Competitive 2-Butenal prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Understanding and Using 2-Butenal: Insights from a Chemical Manufacturer

    Real Experience with 2-Butenal Production

    We’ve worked with 2-Butenal for years, watching its importance grow across both chemical research and specialized manufacturing. This compound doesn’t just offer another building block for our customers. It represents a reliable tool for many in organic synthesis, fragrance creation, and specialty resins. Our day-to-day focus remains on the purity and consistency chemists expect, and that’s how 2-Butenal (also known as crotonaldehyde) earns its place on our product line.

    Model, Specifications, and Practical Details

    Our technical staff handles each batch with direct oversight, controlling parameters from raw material input through final sealing. The colorless to pale yellow liquid comes with a pungent, distinct aldehyde scent. We usually deliver 2-Butenal at a purity of over 99% (GC), water content under 0.3%, and trace impurities tightly monitored. These details matter day in, day out, because downstream reactions depend on narrow margins. Over the years, we’ve witnessed how even slight deviations set off headaches for formulators.

    2-Butenal’s boiling point falls around 104°C, and it carries a density near 0.846 g/cm3. Most of our packaging sits in secure drums of either 180kg or custom quantities as requested. Stability across transport and storage always demands airtight, moisture-free containers—crotonaldehyde reacts with water and oxygen, so we take those safeguards seriously. In real-world operations, we recommend a cool, well-ventilated storage area away from acids and strong bases. Protective gear is standard in our facilities, both for handling and for maintenance staff who work near the filling lines. This comes straight from experience; crotonaldehyde’s reactivity makes caution more than just a regulatory checkbox.

    Common and Critical Applications in Industry

    From our position as a direct manufacturer, the picture is clear—2-Butenal isn’t a vanity product. Customers use it mainly in multi-step organic syntheses where the α,β-unsaturated structure provides unique reactivity. We see it most frequently as a key intermediate for sorbic acid, a widely used food preservative. Some of our longtime clients produce pesticides, tackling the challenge of pest control in agriculture. Another group works with vitamins and pharmaceutical compounds, where this molecule forms the backbone of more complex bioactive substances.

    Requests for technical support often revolve around conjugate addition reactions, for which 2-Butenal delivers unmatched flexibility. Chemists come to us looking for insights on handling the aldehyde—it's more challenging to work with compared to simpler straight-chain aldehydes, largely due to its tendency to polymerize if mishandled. In fragrance chemistry, its strong odor limits direct use, but downstream conversion builds the subtle base notes so many perfumers seek. Our team frequently assists with scaling questions and troubleshooting, ensuring batches run smoothly at kilogram or ton-scale.

    Reliable Quality: What Sets Ours Apart

    A lab can get by with material from various sources, but large-scale users depend on reliability. We control the synthetic route from the ground up, using controlled oxidation of crotyl alcohol or carefully tailored aldol condensations. Each route has its nuances; processing conditions influence not just purity, but also stability in storage. Our years in the business taught us that minor upstream tweaks amplify downstream, so we focus on batch-to-batch reproducibility. It’s not only about hitting a spec on paper—we watch color, volatility, and even subtle shifts in odor during QC assessment. Feedback from returning buyers shows that long-term partnerships grow where surprises stay rare.

    We run every shipment through a full in-house chromatography panel, looking for trace byproducts and confirming identity with both IR and NMR checks. Attempting shortcuts in production often results in unwanted side products, some of which will spoil a sensitive formulation if left unchecked. Our long-term supply contracts reflect that; downstream losses or equipment corrosion cost much more than any minor material savings. So, we keep impurities like propionaldehyde or acetaldehyde under control, even when this means stricter purification cycles and longer reactor time.

    Comparing 2-Butenal with Other Chemicals

    Clients sometimes ask how 2-Butenal compares to other readily available aldehydes—like acetaldehyde, or its isomer, butyraldehyde. The distinction, from our manufacturing bench, lies in the double bond’s position. Crotonaldehyde’s α,β-unsaturated character delivers a chemical handle not present in saturated aldehydes. This allows for Michael additions, Diels-Alder reactions, or further polymerizations. Butyraldehyde, while similar in elemental formula, lacks the double bond and wears a completely different reactivity profile. Customers working on flavorings or fragrance intermediates soon find differences at scale—2-Butenal’s volatility and strong odor make it unsuitable for direct use in many food or fragrance applications, but its chemical activity opens up pathways impossible with ordinary saturated aldehydes.

    Our operation has engineered both processes, and the catalyst handling alone differs between crotonaldehyde and butyraldehyde. You’ll find butyraldehyde appearing more often in plasticizer or solvent manufacture. For 2-Butenal, markets lean heavily toward specialty resins, food additives (after transformation), and fine chemicals. The correct choice depends on intended chemistry; we often walk clients through the pros and cons, drawing on our data from previous runs and stress tests.

    Challenges and Solutions in Handling 2-Butenal

    We’ve seen challenges arise during storage and transfer. Crotonaldehyde reacts easily with atmospheric moisture, forming unwanted polymers or even acids. Left unchecked, this can clog process lines or degrade a batch before it reaches the reactor. Our engineering team solved these issues by implementing nitrogen blankets, double sealing, and regular draining of sampling ports. This investment pays off—in reduced downtime, less maintenance, and higher yield for whoever receives the product next.

    Some clients face issues during the charge and vent steps. Since the vapor is both flammable and pungent, we designed our drum-filling stations with vapor recovery lines and dedicated fume hoods. This kind of detail doesn’t feature in most product brochures, but the plant-floor reality deserves honest treatment. We remain open with users—those planning long production runs should regularly check for micro-leaks, and use lined pipes for prolonged exposure.

    Transport between facilities prompts its own concerns, especially during hot summers. Crotonaldehyde tends to vaporize rapidly at temperatures over 30°C, so our logistics department coordinates temperature-controlled shipments when warranted. Labeling follows all regulatory requirements for hazardous substances, but our real priority is ensuring handlers down the supply chain recognize the product and treat it with the respect dictated by direct experience, not just compliance sheets.

    Safety and Environmental Responsibility

    Safety governs our factory floor policies. 2-Butenal carries both acute toxicity and severe irritant risks for skin, eyes, and airways. We draw on lessons learned over decades—installation of spill containment, full-face shields for operators, and regular air monitoring. Our relationships with neighboring facilities and local authorities ensure rapid communication if any incident occurs. Every tank runs with overfill alarms, and secondary containment keeps product from entering the environment in the unlikely event of a leak. These routines stem from practical, hard-earned knowledge, shared at every training session and reviewed annually.

    On the environmental front, we’ve invested in recovery and abatement units for any process vent streams or accidental emissions. While regulations fix the minimum, real-life scenarios demand backup plans and redundant controls. Our solvent stripping units reclaim volatile organics, cutting both emissions and costs for future batches. In-house waste handling supervisors oversee all hazardous streams, documenting every drum and verifying third-party disposal. Years in business taught us that mistakes compound quickly; vigilance pays off not just in fines avoided, but in the trust built both with regulators and the communities who share the industrial landscape.

    Wastewater receives special treatment before discharge. Crotonaldehyde’s solubility in water means even trace quantities could impact receiving streams. We run dual-stage treatment, with both chemical oxidation and biological polish before effluent leaves the plant. These extra steps avoid downstream headaches, both for ourselves and for county treatment centers. We make these investments willingly, fully aware of our responsibility to the surrounding land and people.

    Supporting Innovation with Practical Know-How

    Many of our partners moved beyond old-school commodity chemistry; they require reliability and technical support from those who know the molecule inside out. Our R&D group regularly collaborates with formulation scientists, troubleshooting everything from pH drift in reactors to off-odors in downstream blends. Sometimes, the call is about a reaction not proceeding to completion; other times, a customer has new applications, such as biodegradable polymers. We learn from these partnerships, improving our production process based on concrete feedback. This loop strengthens both our product and the technical backbone supporting it.

    It’s not rare for chemists at our facility to devise custom purification strategies at a client’s request, balancing yield, speed, and the risk of decomposition. For those with niche needs—be it for isotopic labeling or tighter specifications—we develop protocols rooted in firsthand factory experience, not theoretical lab work. Continuous feedback flows both ways: adjustments that improve process safety or product stability get adopted into our operating procedures. This real-world, results-driven approach gives our clients an edge, and sets us apart from traders with no real stake in the outcome.

    Shaping the Future with Direct Manufacturing Input

    Direct production also gives us foresight into future market trends. Shifting consumer preferences toward safer and greener preservatives drive demand for sorbic acid, with crotonaldehyde as a keystone intermediate. Regulations on volatile organic compounds push us to refine our vent treatment technologies. Every regulatory update, from GHS clarifications to transport law tightening, ripples back to our storage, packing, and documentation systems. We adapt, drawing on both in-house and customer field experience, and keep modernization at the forefront.

    Several universities and industrial partners now explore renewable routes for crotonaldehyde synthesis, hoping to align with emerging bio-feedstock markets. We’ve started pilot programs, evaluating catalytic technologies and fermentation-based processes. These experiments take time to scale, yet the potential to shrink the environmental footprint energizes everyone in the plant. We don’t believe in static manufacturing; steady optimization—whether in batch sizes, energy input, or waste minimization—runs throughout our operations.

    Lessons from Long-Term Supply

    Years of supply chain management underscore the value of direct dialogue with end-users. Unexpected disruptions—be it feedstock instability or logistics bottlenecks—find solutions faster when buyer and manufacturer work as partners. We stick to open communication about projected batch times and address delays rapidly, based on the lessons earned from decades of contract fulfillment. Our customer base includes not just megacorporations, but also nimble, innovative firms eager to experiment and grow. Each has distinct requirements, but all benefit from our willingness to customize production or packaging, drawn from our direct bench chemistry and real flowsheet analysis.

    Because we’re on the manufacturing end, we witness the cumulative challenges of shipping, storage, and inventory directly. Batch traceability doesn’t just satisfy regulations; it enables root cause analysis if any customer issue appears, letting both sides reach resolution efficiently. Real expertise—earned and shared—drives progress in every link of the chain, from loading valves to end-of-pipe emissions controls.

    Final Thoughts on 2-Butenal’s Place in Specialty Chemistry

    Experience tells us that 2-Butenal finds its real strength where chemistry demands both reactivity and precision. Our commitment as a manufacturer reaches beyond the drum’s edge. We supply more than a liquid—users come to rely on hard-won skill, process stability, and ongoing support grounded in practical, daily handling of the chemical. Each batch carries with it lessons learned in both failure and success—shaping safer, more reliable, and more innovative practices for 2-Butenal users around the world.

    We see the process as a collaboration between those who create and those who transform—the chain between raw material and finished molecule powered by relentless refinement. Sharing this expertise openly, while keeping pace with technology and regulation, defines our ongoing work. For those in need of a reactive, high-purity 2-Butenal, a partnership with the direct producer remains the proven route to reliable, insightful chemistry.