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2-Benzylpyridine

    • Product Name 2-Benzylpyridine
    • Alias 2-Benzylpyridine
    • Einecs 212-273-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    321659

    name 2-Benzylpyridine
    CAS_number 1008-30-6
    molecular_formula C12H11N
    molar_mass 169.22 g/mol
    appearance Colorless to pale yellow liquid
    density 1.055 g/cm3
    boiling_point 282-284 °C
    melting_point -18 °C
    refractive_index 1.603
    flash_point 139 °C
    SMILES c1ccc(cc1)Cc2ccccn2
    InChI InChI=1S/C12H11N/c1-2-6-11(7-3-1)9-12-5-4-8-13-10-12/h1-8,10H,9H2
    pubchem_CID 78248
    solubility Slightly soluble in water, soluble in organic solvents

    As an accredited 2-Benzylpyridine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 100 grams of 2-Benzylpyridine, tightly sealed, labeled with hazard warnings, supplier details, and batch number.
    Shipping 2-Benzylpyridine is shipped in tightly sealed containers to prevent leakage and contamination. It should be protected from light, moisture, and extreme temperatures. Packages comply with relevant regulations for hazardous chemicals and are clearly labeled with hazard and handling information. Proper documentation accompanies the shipment to ensure safe and legal transportation.
    Storage 2-Benzylpyridine should be stored in a cool, dry, well-ventilated area, away from sources of ignition and incompatible substances, such as strong oxidizing agents. Keep the container tightly closed when not in use. Store at room temperature and protect from direct sunlight. Use appropriate chemical storage cabinets, ensure proper labeling, and avoid excessive heat or moisture to maintain stability and safety.
    Application of 2-Benzylpyridine

    Applications of 2-Benzylpyridine in Industrial Manufacturing

    As an integrated manufacturer, we supply 2-Benzylpyridine for multiple established chemical industries with strict regulatory and process requirements. Our raw material supports specialized downstream syntheses across advanced intermediates, agrochemicals, and pharmaceutical building blocks, ensuring application-specific consistency, traceability, and technical guidance throughout customer production chains.

    1. Pharmaceutical Intermediate Synthesis

    2-Benzylpyridine acts as a key scaffold for the preparation of specialized heterocyclic intermediates used in the synthesis of antihypertensive, anti-inflammatory, and central nervous system APIs. Leading pharmaceutical plants incorporate it during early-stage route design to introduce the benzyl-substituted pyridine motif, favoring high selectivity reactions for improved downstream yield. Its inclusion directly impacts molecular architecture for final drug candidates.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • United States Pharmacopeia (USP) and European Pharmacopoeia (Ph. Eur.) impurity controls
    • FDA 21 CFR Part 211 for finished pharmaceuticals
    • REACH registration for substances supplied above 1 tonne/year

    Typical usage ratio

    • 0.1–0.8 molar equivalents relative to core reactant, adjusted based on desired intermediate yield and impurity profile

    Downstream process integration

    • Introduced during Grignard-type reactions or transition metal-catalyzed arylation as a nucleophilic partner
    • Subjected to hydrogenation, halogenation, or ring-closure steps to achieve API-relevant intermediates

    Final product types

    • Pyridine-derived pharmaceutical intermediates
    • API fragments for antihypertensive drugs
    • Precursors for CNS and anti-inflammatory medications

    2. Agrochemical Synthesis

    Chemical producers formulate 2-Benzylpyridine as a reactive raw material for the generation of key pyridine-based herbicides and pesticide intermediates. It enables functional group introduction at the benzylic position, facilitating the development of selective crop protection agents. Production plants use it to streamline the construction of novel active ingredient backbones, supporting evolving regulatory and efficiency demands in agricultural markets.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • ISO 9001:2015 Quality Management, focusing on traceability for export
    • Regulation (EC) No 1107/2009 (EU Pesticide Regulation)
    • US EPA 40 CFR Part 158 Data Requirements

    Typical usage ratio

    • 5–15% w/w in reaction batch, dependent on targeted pesticide molecule and required conversion rates

    Downstream process integration

    • Charged to condensation or alkylation steps to form agrochemical actives
    • Further transformed through oxidation or amination for end-use activity tuning

    Final product types

    • Herbicide technical concentrates
    • Intermediates for insecticide and fungicide synthesis
    • Pyridine-based pesticide precursors

    3. Specialty Chemical and Fine Chemical Building Block

    Industrial fine chemical manufacturers adopt 2-Benzylpyridine to serve as a customizable aromatic and heterocyclic feedstock, critical for the creation of specialty ligands and advanced organic intermediates. Enterprises leverage its defined substitution pattern during multi-step syntheses, often where tailor-made ligands, charge-transfer complexes, or fluorescent probes are needed for electronics, research, or material science sectors. This route supports high-purity, customer-specific requirements found in advanced functional material workflows.

    Industry compliance standards

    • ISO 9001:2015 Quality Systems for lot-to-lot reproducibility
    • REACH/CLP compliance for European chemical supply
    • Chinese GB/T standard for organic intermediates
    • SHE (Safety, Health, Environment) audit conformity for major global buyers

    Typical usage ratio

    • 1–10% molar loading in syntheses, adjusted for ligand or dye development and functional group conversion efficiency

    Downstream process integration

    • Utilized at the initial coupling or cyclization stage for advanced organic transformations
    • Included in Suzuki/Miyaura, Heck, or similar catalytic protocols for ligand or probe synthesis

    Final product types

    • Electron transfer agents
    • Specialty ligands for catalysis and coordination chemistry
    • Fluorescent and colorimetric sensor components

    4. Corrosion Inhibitor Precursor for Oil & Gas Applications

    Oilfield chemical formulators integrate 2-Benzylpyridine derivatives as essential structural motifs in the design of tailored corrosion inhibitor molecules. Producers utilize this intermediate in synthetic schemes where nitrogen-containing aromatic cores are required for robust metal surface protection properties under high-salinity, variable pH, and elevated temperature conditions. Its inclusion supports downstream performance in oil extraction and pipeline operation environments.

    Industry compliance standards

    • API RP 14E (American Petroleum Institute Recommended Practice for corrosion control)
    • ISO 15544:2000 (Petroleum and natural gas industries)
    • REACH Annex XVII substances of concern for environmental safety
    • OECD Test Guidelines for ready biodegradability

    Typical usage ratio

    • Often 2–8% by weight in batch synthesis, ratio optimized for required film-forming and adsorption qualities

    Downstream process integration

    • Incorporated during quaternization, Mannich reaction, or alkylation to construct final corrosion inhibitor blends
    • Subject to cationization or surfactant modification for end-use formulation

    Final product types

    • Nitrogen-containing corrosion inhibitor concentrates
    • Pipeline flow assurance additives
    • Oilfield chemical packages for downhole and surface protection

    5. Intermediate for Dyes and Pigment Manufacture

    Manufacturers in the colorant industry employ 2-Benzylpyridine as a precursor to specialized mono- and bis-azo dye intermediates as well as functional pigments. The aromatic system provides both chromophoric and solubilizing features, making it valuable for downstream integration into textile dyes and high-performance pigment classes. Process engineers select the material for its compatibility with steered coupling and diazotization reactions, supporting both coloration strength and fastness properties required in modern applications.

    Industry compliance standards

    • OEKO-TEX® Standard 100 for restricted substances in textiles
    • EN 71-3 Safety of Toy Colorants (migration of certain elements)
    • ETAD guidelines for synthetic organic pigments and dyes
    • REACH Annex XVII limitations for aromatic amines

    Typical usage ratio

    • 3–12% mass fraction per step in dye development, adjusted for hue strength and chemical compatibility

    Downstream process integration

    • Applied at the diazotization/coupling or oxidative reaction step to build chromophore base
    • May undergo sulfonation or additional functionalization for enhanced water solubility

    Final product types

    • Mono-azo textile dyes
    • Pigment intermediates for paints and inks
    • Specialty colorants for plastics and polymers
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    Certification & Compliance
    More Introduction

    2-Benzylpyridine: Perspective from the Production Floor

    Introducing Our 2-Benzylpyridine

    At our facility, producing 2-Benzylpyridine means much more than churning out barrels of a chemical. It’s a process where every batch tells a story of planning, technical know-how, and constant attention to detail. 2-Benzylpyridine, identified by its CAS number 1612-54-8 and chemical formula C12H11N, shows up as a clear to slightly yellow liquid, easy to handle and stable under recommended storage conditions. Our customers in pharmaceutical research and specialty chemicals come to us because they know our product finishes its journey with the consistency, purity, and performance standards they expect—and we do not take their trust lightly.

    What Makes 2-Benzylpyridine Distinct in Chemical Synthesis

    Feature by feature, 2-Benzylpyridine offers a rare blend of reactivity and stability. For researchers, the structural configuration with a pyridine ring linked to a benzyl side chain opens specific doors in synthetic routes. In aromatic alkylation reactions, it presents a different pathway than other pyridines or simple benzyl analogues. Its reactivity as a building block in heterocyclic chemistry, ligand design, and as an intermediate for fine chemical synthesis sets it apart from generic pyridines, which may lack the benzyl functionality that drives certain targeted reactions forward.

    This molecule enters the lab or plant with a clear job: to serve as a bridging element between simpler and more complex structures. For clients specializing in custom pharmaceuticals, access to a well-characterized, uncontaminated batch of 2-Benzylpyridine translates directly into technical success and cost control. Sourcing directly from a manufacturer who controls the full synthetic process gives them confidence that both batch variation and trace impurity profiles stay tightly managed.

    Specifications That Matter to Practitioners

    We produce 2-Benzylpyridine to a minimum purity of 98 percent, as measured by GC and HPLC. This threshold isn’t arbitrary. Typical downstream applications—intermediates for API creation, catalyst development, and academic synthetic research—can stall or skew dramatically whenever an upstream impurity falls outside specifications. Our team patrols not only purity but identity—confirming every lot with spectroscopic fingerprints, especially 1H NMR and mass spec, before it ever leaves our plant.

    Physical details count. Practitioners in the lab appreciate our care in ensuring a narrow boiling range and consistent appearance across shipments. Packing in amber glass is standard, not just for compliance but because we know how light sensitivity, even for some days in transit, can lead to side reactions—something we learned by seeing subtle changes under less controlled shipments. Ultimately, whether a customer is scaling up a pilot or fine-tuning a research route, knowing the physical and chemical behavior of each shipment allows for repeatable, reliable performance.

    Safety, Handling, and Real-World Use Cases

    Sitting on our production benches and watching shipping crates head out, we rarely forget that real people handle our materials every day. 2-Benzylpyridine needs ordinary chemical precautions—nitrile gloves, splash goggles, careful fume hood use. Over time, we have tracked how customers use it: often in stepwise alkylation processes, selective functionalization, and as a scaffold in the creation of ligands for transition metal catalysis. Some R&D groups request custom volumes or concentrations, and our production line has been adapted to meet those asks without compromising batch-to-batch consistency.

    We have seen this molecule find new life in projects far from its original application. Researchers in electronic material development sometimes request it as a precursor for functionalized heteroaromatic monomers. There, every minor impurity matters; conductivity, film formation, and reproducibility can swing wildly based on seemingly trivial residues. Trust built from careful attention to those “minor” details has kept some of our earliest customers working with us for years.

    2-Benzylpyridine Vs. Other Pyridines and Benzyl Analogues

    In the large family of pyridine derivatives, many are sensible choices for nitrogen-containing intermediates. 3-Benzylpyridine and 4-Benzylpyridine exist, but if the target chemistry relies on electronic effects or positional selectivity provided by the 2-benzyl placement, no substitute works. We field questions from synthetic chemists who discover the nuances only after running side-by-side screening of various isomers. Over time, the reputation of 2-Benzylpyridine for delivering targeted effects—directing groups, influencing regioselectivity, or improving yields in cross-coupling—directs teams away from other variants, particularly where steric and electronic balance is critical.

    We sometimes receive requests comparing its performance with simple unsubstituted pyridine or with toluene-based scaffolds. What we’ve seen is that while generic pyridine often acts purely as a base or a ligand, 2-Benzylpyridine can actively participate in structure formation through the aromatic methylene group. That methylene gives a new handle for further modification or crosslinking. It’s not just another “nitrogen base”—it’s a carefully tuned intermediate that’s been matched to its contemporary challenges.

    Why Source 2-Benzylpyridine Directly from a Producer?

    Plenty of laboratory supply houses transact in 2-Benzylpyridine, but as a manufacturer, standing behind each batch matters. We control the upstream sources, including parent pyridine and benzyl halide stocks, so batch homogeneity and traceability don’t get lost between middlemen. Clients buying from traders sometimes encounter mystery returns, unexpected delays, or unexplained quality problems. Our direct relationship ensures users know exactly what went into each bottling—down to each solvent lot, reaction temperature range, and purification condition.

    This direct knowledge has another advantage: custom formulation and scale. We can shift from small research-grade bottles to multi-kilo drums, clean-room packing, or specific solvent blends if a customer’s protocol demands it. Years of hands-on problems—temperature shifts in reaction vessels, material incompatibility in container linings, loss of yield in shipping—have all shaped how our team runs the floor. There’s an ownership and immediacy that no secondary wholesaler can match.

    Real Problems, Real Solutions

    Occasionally, we see supply chain disruptions for key precursor chemicals. The effect flows downstream, impacting not only price but also purity and delivery predictability. We have modified our synthesis schedule and buffered by holding larger inventories. With honest communication, clients know ahead of time when scheduling challenges or input substitutions could occur. This transparency reduces research downtime and project delays for our partners.

    Keeping the conversation open means soliciting feedback on application challenges. Some research projects hit bottlenecks that generic specifications fail to solve. We have developed higher-purity and special-grade 2-Benzylpyridine for select projects, including ultra-low water content lots for moisture-sensitive organometallic routes. It took extra time and cost, but seeing a customer’s advanced catalyst program finally reach scale validated every hour invested.

    Environmental Responsibility and Worker Safety

    Producing specialty chemicals isn’t a closed loop—we live with the impact of every shift, spill, and emission. Our plant operates under clear environmental targets. For each 2-Benzylpyridine batch, we aggressively minimize solvent residues, recycle mother liquors where possible, and use scrubber technology to keep airborne pyridine and benzyl intermediate emissions below established guidelines. We’ve upgraded containment systems after learning firsthand how accidental releases affect not only our own work culture, but the neighborhoods nearby.

    Inside the plant, worker safety shapes every standard operating procedure. By limiting manual handling and automating transfers, exposure drops. Regular process reviews look for new ways to cut energy and material waste, too. Our goal—making sure each drum shipped means as little legacy waste as possible and that each team member heads home as healthy as they started.

    2-Benzylpyridine in Research and Industry: Beyond the Lab Bench

    The flexibility of this molecule stretches beyond synthesis for drug intermediates. Some material science groups find novel applications, from polymer modification to trace metal detection. We respond to pilot requests ranging from a few grams to hundreds of liters. For certain flavors or fragrance developments, 2-Benzylpyridine takes on the role of a trace precursor, contributing distinct notes to complex formulations—not as a direct additive, but as a transient, reactive species. Though these uses remain niche, each has required tweaks in purification and formulation specific to the task at hand.

    Our team enjoys collaborating with new fields. For example, electrochemical research groups in Europe have explored 2-Benzylpyridine as a precursor for heteroaromatic conductive materials. They ask hard questions about residual ions, trace halogen content, and stability under conditions outside ordinary storage. Over multiple rounds of feedback, we’ve improved our processes simply by listening and adapting, and this cycle of improvement means later researchers reap the benefits.

    Feedback, Traceability, and Continuous Improvement

    Constant vigilance—this almost sums up our attitude toward quality. Decades in chemical production taught us that traceability solves not only technical mysteries but also builds confidence with each shipment. Every label we attach links directly to a logbook recording the batch start time, raw material lot number, yield, and every analytical result.

    After each delivery, our technical team asks for direct feedback. If a user stumbles over solubility, volatility, or unexpected reactivity, we investigate, test, and document. A sharp-eyed researcher in Japan once caught a minor issue with headspace contamination. Our follow-up led to a process redesign in our purification section, helping us eliminate a class of low-level volatile byproducts permanently. Each issue—minor or major—gets faced with the same seriousness, and all customers benefit from these iterative improvements.

    Why End-Users Value Direct Manufacturer Relationships

    Researchers, process engineers, and formulation scientists want a product they can use with confidence—not one that brings guesswork into high-stakes projects. Being the manufacturer, we assure them a direct line to those who understand both the batch chemistry and the real implications of slight deviations. Our role begins not with marketing brochures but with a technical discussion of real needs. If we create a product for a novel organocatalysis application, for an emerging battery technology, or even for a classic ligand synthesis, we embed the accumulated knowledge of hundreds of previous users into each batch.

    Supply chain hiccups, inconsistent timelines, and unknown storage histories often plague buyers using indirect procurement. From our side, direct engagement is far more efficient—both sides save time and lower the risk of errors. Whether it’s urgent overnight deliveries or routine annual contracts, the connection to the whole production and technical support team pays off in customer trust.

    Commitment to Reliable, Science-Backed Solutions

    Our plant sits at the intersection of research needs and large-scale production realities. That responsibility means we track scientific trends and respond to regulatory changes, but most of all, we keep learning from those who use 2-Benzylpyridine day in and day out. If a global regulation tightens allowed impurity levels or bans a process solvent, we get to work on a new solution.

    Our journey with 2-Benzylpyridine is not static. Shifts in customer requirements, new analytical capabilities, and resource challenges keep us alert. We don’t rest on “good enough.” Whether it’s increasing batch purity, improving packaging integrity, or offering more lot-specific documentation, changes reflect a running dialogue with science.

    Looking Ahead: Building on Experience

    Day after day, producing 2-Benzylpyridine means more than overseeing reactors and paperwork. It’s collaborating with R&D teams, supply chain partners, and regulatory specialists to solve present and future challenges. Standing in a plant, surrounded by tanks and control panels, connects us persistently back to the labs and industries that transform our product into innovations we never imagined a decade ago.

    As demand changes, so will the needs of those who depend on our product. We’re preparing for greener chemistries, more detailed batch data, and support for more demanding applications beyond what’s “standard” right now. It’s about building a relationship with science—one where quality, safety, and experience lead the way, grounded in real production practices and honest communication.