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HS Code |
956111 |
| Productname | 2-Aminophenol Hydrochloride |
| Casnumber | 600-23-7 |
| Molecularformula | C6H8ClNO |
| Molecularweight | 145.59 g/mol |
| Appearance | White to off-white crystalline powder |
| Meltingpoint | 174-178°C |
| Solubility | Soluble in water |
| Purity | Typically ≥98% |
| Odor | Odorless |
| Storagetemperature | Store at 2-8°C |
| Ph | Acidic in water solution |
| Synonyms | o-Aminophenol hydrochloride |
| Boilingpoint | Decomposes before boiling |
| Stability | Stable under recommended storage conditions |
| Hazardclass | Irritant |
As an accredited 2-Aminophenol Hydrochloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 2-Aminophenol Hydrochloride, 100g: Supplied in a sealed amber glass bottle with tamper-evident cap and clear hazard labeling. |
| Shipping | 2-Aminophenol Hydrochloride is shipped in tightly sealed containers to prevent moisture absorption and contamination. The packaging complies with hazardous materials regulations, including appropriate labeling and cushioning to avoid breakage. It is transported in cool, dry conditions and handled by trained personnel, ensuring safety during storage and transit. |
| Storage | 2-Aminophenol Hydrochloride should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from moisture and incompatible substances such as strong oxidizers. Protect it from light and avoid prolonged exposure to air. Store at room temperature and ensure the storage area is clearly labeled and compliant with relevant chemical safety guidelines. |
Applications of 2-Aminophenol Hydrochloride in Industrial ManufacturingAs a chemical raw material producer, we supply 2-Aminophenol Hydrochloride to manufacturers operating in demanding industrial fields. Below, we detail key downstream applications, compliance standards, manufacturing ratios, integration steps, and typical finished products in each sector. 1. Dye and Pigment Intermediates in Fine ChemicalsLeading dye and pigment manufacturers use 2-Aminophenol Hydrochloride as an essential intermediate for synthesizing azo and sulfur dyestuffs, specially targeted for textiles, leather, and paper coloration. The compound enters dye synthesis via nucleophilic substitution or coupling processes, enabling the controlled development of custom chromophores and precision-shaded dyes. Quality control requires traceability for each batch entering multipurpose fine chemical facilities. Industry compliance standards
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2. Pharmaceutical Intermediate for Paracetamol SynthesisPharmaceutical companies source 2-Aminophenol Hydrochloride for use as a key intermediate in paracetamol (acetaminophen) production via acetylation processes. Controlled conversion ensures purity and yield, with trace impurity analyses carried out at each stage to comply with global pharmacopoeias. Batch records and GMP-compliant documentation are mandatory throughout the active ingredient manufacturing chain. Industry compliance standards
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3. Antioxidant Additive in Industrial Lubricant FormulationProducers of industrial lubricants and metalworking fluids utilize 2-Aminophenol Hydrochloride as a functional antioxidant to suppress oxidative degradation at elevated temperatures and in harsh environments. Process engineers incorporate this additive at precise concentrations following solvent blending or base oil pre-treatment to ensure long-term stability and metal compatibility, validated through accelerated aging and corrosion resistance tests. Industry compliance standards
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4. Developer Component in Photographic Chemical ProcessingPhotographic and imaging industry manufacturers use 2-Aminophenol Hydrochloride as a developer agent for black-and-white photo processing, contributing its reductive properties in silver halide reduction. It is formulated in proprietary mixtures after dissolution in aqueous or buffered solutions to achieve uniform image contrast and tonal quality. Handling and processing align with environmental and occupational safety standards for darkroom chemicals. Industry compliance standards
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5. Corrosion Inhibitor Synthesis for Water Treatment ChemicalsManufacturers of corrosion inhibition products for industrial water treatment utilize 2-Aminophenol Hydrochloride as a precursor in the synthesis of anti-corrosive agents targeting steel and copper systems. In these formulations, precise molecular modification enables the production of water-soluble inhibitors that extend asset life in boilers, cooling towers, and heat exchangers, under strict monitoring of amine residuals and treatment compatibility. Industry compliance standards
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Across decades of hands-on manufacturing, we’ve seen the difference that well-controlled 2-Aminophenol Hydrochloride (model: APH-HCl, CAS 137-08-6) brings to chemical processes. In our production lines, APH-HCl stands out for its purity and batch-to-batch consistency. Our engineers focus on minimizing metallic contaminants and adjusting particle size to fit processes in dyes, pharmaceuticals, and specialty chemicals. It doesn’t just fill a spot on a shelf — real value lies in how it supports reliable yields and fewer headaches down the line.
We don’t stop at purity figures. We monitor residual water content and keep chloride levels tightly controlled, as even minor fluctuations can throw off sensitive downstream reactions. In the dye industry, for example, APH-HCl remains in demand for its role in making azo dyes and developing color-forming intermediates. Product stability, especially during transit and storage, matters most to our clients. Our dedicated storage procedures and moisture-proof packaging keep the product free from caking or chemical degradation—problems that often show up with lower-grade sources.
From years in the business, we’ve learned that 2-Aminophenol Hydrochloride solves process headaches chemists face with oxidations, couplings, and condensations. In pharma synthesis, APH-HCl helps build essential intermediates for analgesics, antipyretics, and even hair dye ingredients. By keeping our pH targets strict and controlling the color index, we reduce the risk of batch failures, particularly during scale-up.
Compared with other starting amines, APH-HCl offers better solubility in water and lower dusting, which cuts down both respiratory hazards and clean-up time. We get fewer calls about clogged pipelines or material bridging during feed—reality-based advantages that stem from manufacturing choices at our facility. For custom projects, we can modify the particle size or supply the material in granulated form, based on hands-on experience with various reactor configurations.
Buyers often weigh 2-Aminophenol base against the hydrochloride salt. The salt form brings distinct advantages. It handles humidity better, which means no sudden clumping during humid shipping conditions. The hydrochloride version also mixes easily with aqueous systems, saving time during formulation steps. We’ve known customers in the pigment sector who switched to APH-HCl and reported a noticeable reduction in filtration time and product loss.
Unlike generic offerings sourced through layered resale channels, our APH-HCl ties back to controlled internal QA, and we give attention to every detail, from neutralization pH to final drying cycle. This discipline not only enhances reproducibility but limits unwanted side-products, which can cause regulatory or performance issues. Our product rarely triggers complaints about off-odors, which crop up in less refined batches.
Over years of running kilo to multi-ton batches, we’ve seen APH-HCl slot into a surprising range of chemistries. In dye manufacture, it stands as a building block for both basic and advanced colorants. Textile labs lean on it for diazo coupling reactions, while downstream veterinary pharmaceutical plants use it in antipyretic formulations. We’ve delivered shipments to labs developing antimalarial intermediates, where moisture stability kept rejections near zero. It’s also found a place in photo developers, antioxidants, rubber accelerators, and niche research settings.
End users reach out for help when troubleshooting unanticipated side-reactions. With direct manufacturing under one roof, we draw from real case experience, not just textbook examples. For instance, when a customer’s azo dye yield dropped unexpectedly, close scrutiny of trace metal content in our APH-HCl revealed a slight batch variation. Tweaking our recrystallization step restored their process yield. This sort of feedback loop between producer and user makes a deeper, practical difference.
Our internal specs cover color, content, and impurity profile. Yet, the truer story surfaces in user labs: high reproducibility means fewer do-overs and less waste. Returning customers often cite the "non-hygroscopic" property, a direct result of our drying process and dedicated packing line. Over time, we’ve tweaked our manufacturing to limit the aromatic amine impurity fraction, aiming at requirements well below what industry specs set as minimums.
This difference defines why some manufacturers attract steady, long-term partnerships while others chase spot price. Consistency of APH-HCl links directly to reduced rejects in dye coupling tanks and more reliable yields in pharmaceutical intermediates. Hard-won knowledge guides each production change—something not gained by brokers handling only paperwork.
Environmental responsibility isn’t just a slogan. Our approach focuses on solvent recycling and using closed systems for acidification and crystallization. These steps reduce waste acid discharge—a real challenge in aminophenol chemistry. Over the years, these improvements have also benefited product purity, as tighter controls on internal recycling limit cross-contamination and stabilize output.
Clients dealing with strict regulatory requirements, especially in pharma and veterinary sectors, often quiz us on traceability. Our lot tracking allows backward investigation down to raw material batches, removing the guesswork common among traders or contract packagers. These systems didn’t develop overnight. They evolved from real-world audits and supplier qualification cycles, where gaps in traceability cost everyone time and effort.
Not all 2-Aminophenol hydrochlorides are equal. Variations in production routes—reduction of nitrophenol in batch versus continuous lines—leave hard-to-predict fingerprints on purity and side product pattern. We've compared our output with commercial lots from both domestic and global suppliers. Some showed inconsistent moisture content, and others failed at stability during long sea journeys.
Through holding direct control over reduction, neutralization, and filtration, we hold responsibility in-house. If an issue does come up, we resolve it ourselves, not through a web of emails to upstream providers. That’s a difference many downstream processors appreciate, especially those that can’t afford batch failures caused by incoming material drift.
We’re equipped for both bulk tanker loading and custom-packed laboratory lots. After client feedback, we shortened lead times and offer buffer storage for repeat contracts. That way, urgent lines never stall due to raw material gaps. Bulk customers who switched to us from fragmented resellers report sharper production scheduling and lower holding costs, since our lot-to-lot uniformity reduces surge ordering for blends or rechecks for quality.
Supporting R&D means more than just small deliveries. We've answered direct technical questions—about downstream color reactions, solubility in non-aqueous solvents, and even pilot plant troubleshooting. Our team draws from first-hand manufacturing and application backgrounds so conversation isn’t just sales talk.
No product line stays free from issues. In APH-HCl production, atmospheric oxidation control, filter efficiency, and consistent acidification levels top our list. Years ago, we faced shipment returns due to excessive chlorine odor. That wake-up call led us to update our ventilation and neutralization protocols. Now, chlorine volatilization sits far below actionable limits by international guidelines.
Clients processing APH-HCl into advanced intermediates sometimes face filtration slowdowns during rainy seasons. Early batches would cake inside drums from unplanned humidity spikes. We overhauled our storage and drying operations, and we added humidity indicators in each drum. It cut off complaints and reduced time spent breaking up material at customer sites.
Waste minimization matters both for cost and community acceptance. Closed-loop filtration and investment in acid recovery tanks came from practical problem solving—government fines and rising effluent costs provided the push. Over a few years, we dropped our waste output by nearly half, making operations more stable and projects easier to sustain.
Year-round, we run application tests using our current-lot APH-HCl in real chemical formulations. These go beyond mere compliance checks—they show if small-scale adjustments on the line made a difference in color strength, solution clarity, or reaction time compared to competitor products. This loop, connecting plant engineers, lab chemists, and technical sales, keeps us close to user realities and pins down what buyers actually find valuable, instead of just quoting out-of-context specs.
We see some labs using the base form and converting it in-house to the hydrochloride. That route looks cheaper on paper. Direct use of APH-HCl, though, eliminates an extra neutralization and drying cycle, saving overhead and lowering exposure in plant rooms that struggle with aromatic amine odors. That’s not theory—we’ve seen clients realize both safer workspaces and tighter material controls.
As synthesis and regulatory rules evolve, APH-HCl faces new demands. Some buyers now specify even lower levels of trace metal contamination. We invest in high-sensitivity detection—atomic absorption, ion chromatography—so our output meets tomorrow’s standards. These upgrades don’t just satisfy inspectors; they stem from long-term feedback cycles with researchers who regularly stretch chemical performance limits.
Moving forward, reduction in process solvents, greener acids, and even bio-based synthesis options come under discussion at our facility. Some of these changes need more research to match the quality of current routes, but we pursue these directions not as PR, but out of genuine necessity to keep production both safe and competitive.
People in the chemical business know products like 2-Aminophenol Hydrochloride can get treated as simple raw material lines. Our approach comes from knowing that process failures, operator concerns, or regulatory surprises crop up not from a lack of data but from unseen differences in how materials are made, handled, and delivered. Through every shipment, we build in lessons learned, whether about improved filtration, longer shelf life, or reduced hazardous waste.
Chemical users in dyes, pharma, or specialty intermediates rely on producers who stand behind their batches. Years of staying close to the shop floor and listening to user struggles helps us deliver material that minimizes trouble where it actually occurs. That’s the story of our APH-HCl—not just another amine salt, but a product kept reliable through real-world experience, process tuning, and ongoing investment in the small details technical teams count on.