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2-Aminophenol

    • Product Name 2-Aminophenol
    • Alias o-Aminophenol
    • Einecs 200-453-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    899286

    ChemicalName 2-Aminophenol
    CASNumber 95-55-6
    MolecularFormula C6H7NO
    MolecularWeight 109.13 g/mol
    Appearance White to light purple crystalline solid
    MeltingPoint 174-176 °C
    BoilingPoint 174 °C (decomposes)
    SolubilityInWater Soluble
    Density 1.293 g/cm³
    pH 7.2 (10 g/L, 20 °C)
    FlashPoint 164 °C
    Odor Odorless or slight phenol-like odor

    As an accredited 2-Aminophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 2-Aminophenol is packaged in a sealed, amber glass bottle containing 500 grams, featuring a chemical-resistant screw cap and hazard labels.
    Shipping **2-Aminophenol** should be shipped in tightly sealed containers, protected from moisture and incompatible substances. It should be labeled according to regulatory requirements (e.g., UN2651 for hazardous materials), and handled by trained personnel. Ensure proper documentation, and transport in accordance with local, national, and international regulations for hazardous chemicals.
    Storage 2-Aminophenol should be stored in a tightly closed container in a cool, dry, well-ventilated area, away from sources of ignition, heat, and incompatible substances such as oxidizers and acids. Protect from light and moisture. Use secondary containment to prevent leaks or spills, and clearly label the storage area. Ensure appropriate safety practices and access restrictions for authorized personnel only.
    Application of 2-Aminophenol

    Applications of 2-Aminophenol in Industrial Manufacturing

    2-Aminophenol plays a key role in several critical chemical manufacturing segments. With precise composition and controlled purity, our facility supports large-scale formulation and downstream integration for a range of established industries. Below are major application sectors, with specific compliance, formulation requirements, in-process roles, and resulting end products.

    1. Dyes and Pigments Manufacturing

    Major dye producers rely on 2-aminophenol as a core intermediate in the synthesis of azo dyes, sulfur dyes, and metal-complex colorants. Production requires strictly monitored input ratios and precise reaction timing. We maintain contaminant controls and batch-traceable documentation to enable use in high-performance textile and leather dyes. During colorant manufacture, chemical reactivity, isomer content, and residual impurities directly influence downstream uniformity and shade reproducibility.

    Industry compliance standards

    • REACH (EC 1907/2006) Registration and Substance Evaluation
    • OEKO-TEX Standard 100 requirements for dye intermediates
    • ZDHC MRSL (Zero Discharge of Hazardous Chemicals Manufacturing Restricted Substance List)
    • ISO 9001:2015 Quality Management System certification for raw materials

    Typical usage ratio

    • Ranges from 5% to 12% by molar ratio in diazotization and coupling reactions for azo dye synthesis
    • Adjusted according to target dye load and desired color intensity

    Downstream process integration

    • Charge 2-aminophenol to the reaction vessel during the initial condensation or diazotization stage
    • Monitor pH and temperature to avoid side reactions and optimize conversion rates
    • Analyze intermediate purity before further coupling or sulfonation steps

    Final product types

    • Dyes for synthetic fibers and cotton
    • Leather colorants and printing inks
    • Paper colorants
    • Technical pigment dispersions

    2. Pharmaceutical Active Ingredient Synthesis

    2-Aminophenol forms an essential building block for several non-steroidal anti-inflammatory drugs, cold remedies, and muscle relaxants. It undergoes condensation, etherification, or amidation under cGMP protocols. Our plant secures medical-grade traceability with controlled residual solvent analysis and compliance paperwork for regulatory audits. Lot selection addresses critical process impurity carryover requirements imposed by pharma intermediates and final APIs.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • USP-NF (United States Pharmacopeia–National Formulary) ingredient monographs
    • EDQM CEP (Certificate of Suitability) for API starting materials
    • 21 CFR Part 210/211 for process and packaging controls

    Typical usage ratio

    • 0.6 to 1.3 molar equivalents relative to other reactants in intermediate synthesis for acetaminophen and related analgesics
    • Adjusted based on process step and impurity control targets

    Downstream process integration

    • React in closed reactor systems, with online monitoring of amino group conversion and hydrolysis byproducts
    • Purify by crystallization or recrystallization where dictated by downstream processing specs
    • Quality release after residual solvent and impurity panel confirmation

    Final product types

    • Paracetamol (acetaminophen) bulk drug intermediate
    • Muscle relaxant active ingredients
    • Antipyretic and analgesic compounds
    • Intermediate precursors for pharmaceutical fine chemicals

    3. Rubber Chemical Additive Production

    Downstream manufacturers of antidegradants and stabilizers incorporate 2-aminophenol for its oxidative and photoprotective properties. It acts as a precursor for products such as p-phenylenediamine antioxidants. During synthesis, careful control of amination, solvent removal, and side-product elimination directly determines additive efficacy and batch-to-batch reproducibility. Our technical team supports direct consultation for compound formulation and supply chain validation.

    Industry compliance standards

    • ASTM D4679 for rubber compounding materials
    • ISO 9001:2015 QA for specialty chemical production
    • Regulation (EU) 2019/1021 (POPs - Persistent Organic Pollutants), especially PAH monitoring
    • National and international tire industry safety protocols (e.g., ECE-R30 for passenger car tires)

    Typical usage ratio

    • 3% – 9% by weight in synthesis of rubber antioxidants, depending on the final compound structure
    • Dosage varies with targeted protection level against heat, UV, or ozone exposure

    Downstream process integration

    • Melt or solution blending in presence of base or acid catalysts
    • Sequential batch processing with close monitoring of conversion and by-product profile
    • Downstream purification before final product formulation

    Final product types

    • Rubber antioxidants (e.g., 6PPD, IPPD intermediates)
    • Heat and light stabilizers for tire and industrial rubber products
    • Compounded elastomer additives
    • Protective coatings for rubber profiles

    4. Photographic and Imaging Chemical Production

    Producers of photographic developers incorporate 2-aminophenol in metol-type and black-and-white printing formulations. Analytical QC on purity and trace metals content is essential, as small dosage shifts influence image tone, grain, and developer longevity. Our process lines provide color index tracking and fine crystal control to match performance requirements set by photographic chemical brands. Safe materials handling procedures align with specialized storage rules and batch isolation for these high-purity imaging intermediates.

    Industry compliance standards

    • ISO 18913:2012 Imaging materials — Stability of photographic color images
    • ANSI IT 9.1 (Photographic Processing Chemicals — Specification for Photographic-Grade Chemicals)
    • RoHS Directive (2011/65/EU) for hazardous substance limitation
    • Company-specific chemical purity and trace contamination specs for professional photographic products

    Typical usage ratio

    • Ranges from 0.5% to 3% by weight in finished developer working solutions
    • Dosing depends on image contrast performance and replenishment rates

    Downstream process integration

    • Direct dissolution into aqueous powder blends during developer manufacturing
    • Controlled addition prior to final mixing and pH buffering
    • Storage in light- and moisture-resistant packaging to prevent premature oxidation

    Final product types

    • Black-and-white paper developers
    • Film development concentrates and ready-to-use kits
    • Photographic printing solutions for commercial labs
    • Analytical-grade imaging reagents

    5. Agrochemical Intermediates Production

    The agrochemical sector utilizes 2-aminophenol as a starting intermediate for synthesis of select herbicides and plant protection agents. Material purity, low-halogen contaminant profile, and controlled particle size are critical for scale-up and downstream formulation. Our operations comply with agricultural safety and environmental standards, supporting traceable batches for regulated pesticide intermediates.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • ISO 9001:2015 production traceability requirements
    • EU Regulation (EC) No 1107/2009 (placing of plant protection products on the market)
    • GLP (Good Laboratory Practice) for intermediate validation

    Typical usage ratio

    • 4% to 10% by weight relative to total precursor mass during initial condensation and ring-substitution steps
    • Formulation adapted based on downstream active ingredient pathway

    Downstream process integration

    • Batch charging with direct-inlet addition during agro-intermediate chemical synthesis
    • Monitored for reaction selectivity, temperature, and impurity generation
    • Purification to target technical or analytical grade depending on formulation need

    Final product types

    • Selective herbicide intermediates
    • Plant growth regulator active ingredient precursors
    • Crop protection formulation bases
    • Technical pesticides requiring aminophenol intermediates

    6. Specialty Resin and Polymer Production

    Producers of specialty phenolic resins use 2-aminophenol to introduce high-resistance structural elements into molding compounds, electronics encapsulants, and adhesive binders. The input quality directly impacts heat resistance and mechanical strength metrics. Facility-level batch separation and pre-conditioning manage internal handling risk given the material’s reactivity profile. All resin production follows documented procedures to align with electronics, automotive, and construction resin application standards.

    Industry compliance standards

    • UL 94 Flammability Standard for Plastics Materials
    • ISO 14001 Environmental Management Systems (for chemical processes)
    • IEC 60695-2-11: Fire hazard testing of polymer materials
    • RoHS compliance and SVHC registration for electronics components

    Typical usage ratio

    • 1% to 7% by weight relative to total monomer mass for modified resin synthesis
    • Adjustment based on targeted rigidity and insulation performance

    Downstream process integration

    • Introduce during pre-polymerization step or with co-monomers in batch reactors
    • Tightly regulate exotherm and polymer chain termination during resinification
    • Post-synthesis blending with fillers and curing agents before molding or casting

    Final product types

    • High-performance phenolic and epoxy resins
    • Encapsulation materials for electronic assemblies
    • Industrial adhesives and sealants for automotive and circuit board construction
    • Heat-resistant foam and molding compounds
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    Competitive 2-Aminophenol prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    2-Aminophenol: Experience, Application, and Reliability from the Manufacturer’s Floor

    From Raw Material to Specialty Chemistry—A Story of Practical Application

    Chemistry always finds its champions among those who test it in real process streams amid pressure, heat, and the steady rhythm of reactors. 2-Aminophenol traces its way through our plant floors, starting as an unassuming white to grayish crystalline powder, punching far above its weight in a sprawling list of real-world contexts. We manufacture this product under controlled batch conditions, keeping impurities low, and maintaining color and consistency across every lot. Across the years, every drum leaving our facility holds the result of thousands of hours fine-tuning not just yields, but workability on customer lines in dyes, pharmaceuticals, and fine chemical production.

    Physical Assurance: Purity, Moisture, and Color as Reliability Markers

    End-use behavior rests on tangible properties. Our 2-Aminophenol typically clocks in at above 99% purity, confirmed by HPLC methods and reinforced by routine lot tracking. Moisture is not an afterthought; it can shift performance in downstream manufacturing, so finished stock rotates through a desiccation protocol and rapid test schedule. Most customers who work in dye synthesis or in intermediate formation for paracetamol surf through the batch data, comparing color, granule distribution, and caking tendency. We keep tight control on the color index because processes downstream—like azo dye couplings—demand clarity and minimal background interference.

    Practical Chemistry: Batch Records and Traceability

    Serious manufacturers never operate on hope—batch records anchor every kilo of product. Our 2-Aminophenol carries legible manufacturing trails, from raw aniline source, nitrosation points, reduction conditions, all the way to packaging. This doesn’t just serve compliance. It protects customers whose final product gets scrutinized in regulatory or pharmaceutical contexts. Any deviation—even before a problem arises—can mean thousands in lost time. Traceable origins save these costs before they even have a chance to build up.

    On-site Experience Defines Our Perspective

    Chemist, operator, and logistics manager each see 2-Aminophenol in a different light. Batch development teams work in fume hoods, verifying crystallization times with scrutiny; the operators know deviations in particle size can choke a feeder. We’ve worked with clients whose filtration steps gummed up because of minor, but real, shifts in physical properties. We welcomed visits to our site to test their critical tests against our outgoing stock, using their own process water and blend ratios. More than one technical success came out of these hands-on sessions, catching micro impurities or solubility hiccups before they became broader failures.

    Specifity over Versatility—How This Product Fills Its Unique Role

    2-Aminophenol does not try to fight for space as a general-use intermediate. It fits meticulous specifications found in dye manufacturing (especially for metal-complex dyes and developers), specialty rubber chemicals, and certain pharmaceutical syntheses where nothing else does the job as efficiently. We have spent months side-by-side with end-users optimizing their outcome—not just pushing lots. Pharmacopoeial-grade batches solve unique issues in acetaminophen (paracetamol) synthesis. The difference from synthetic alternatives—like para-isomers or substituted phenols—shows up in yield, ease of purification, and downstream safety profiles.

    Batch Consistency: The Manufacturer’s Constant Challenge

    Seasonal fluctuations, feedstock differences, minute environmental shifts—all play havoc with outcomes if left unchecked. What separates the benchwork from real production lies in diligence more than clever chemistry. Each tank wash, each transit container, every change in steam quality—these show up as subtle batch differences. Our years of production uncovered that filtration speed or an extra rinse sometimes leap to the foreground in the customer’s process, especially in ton-scale dye houses. Trading stories with plant managers and R&D chemists sharpened our approach. Challenges do not get buried under paperwork: Real feedback, usually in the form of phone calls about unusual reactivity or unexpected residues, drives direct corrections at the manufacturing line.

    Contaminant and Impurity Control

    The difference between a reliable 2-Aminophenol and a compromised one often lies in milligrams per kilo of off-specification compounds. We did not set out solely to meet commercial specs; we committed to exclusion of chlorinated byproducts, residual aniline, and transition metal residues that foul reactions or introduce risk in pharmaceutical use. Each batch undergoes spectral purity checks—by UV, IR, and targeted wet chemistry—because downstream science or regulatory inspection rarely forgives oversights. In recent years, project partners demanded even tighter quantification for nitrosamine precursors after heightened regulatory attention. We adapted, integrating new testing to avoid byproduct nightmares for their final dose-formulation.

    Storage, Handling, and Kirsty’s Story

    Few people appreciate how quickly 2-Aminophenol darkens or cross-reacts if mishandled. One of our earliest sales supervisors, Kirsty, learned this first-hand. Years ago, a warehouse trial left a shipment exposed to high humidity. Not only did the surface oxidize, but the client’s production lines suffered blocked filters for weeks. We responded with strict pallet shrink-wrapping, smaller drum units, and a no-shortcut storage protocol. This hands-on lesson paid dividends for every kilo shipped since. No process step sits untouched by operator-focused packaging and real feedback loops.

    Human Scale: Training and Process Safety

    We have trained every operator on phenolic handling, with documentation not for bureaucracy but for confidence at 3 AM, mid-run, when a batch smells off. Strict adherence to safety—proper exhaust, skin protection, and emergency procedures—go beyond regulatory statements. People who handle these materials daily understand instantly why respirator and glove policies are more than paperwork. Routine drills and anonymous feedback channels caught near-misses well before they grew into incidents. By grounding chemical safety in daily realities, not blame, we keep both product and people in optimal condition.

    Comparing 2-Aminophenol to Similar Products—Experience Over Labels

    No two phenols behave identically. The ortho isomer carries unique reactivity for coupling reactions—try substituting paracetamol campaigns with cheap alternatives and yields, color, or safety profiles deteriorate. Competing products—like 4-aminophenol or substituted cresols—do not slide seamlessly into every recipe. Years of feedback from dye manufacturers and pharmaceutical syntheses cemented the case: cost savings through one-size-fits-all intermediates backfire with off-shades, poor filtration, or unexpected impurities. We encourage formulation trials with our own product and alternatives side-by-side. Every batch we ship has been compared in our own pilot work-ups against market norms. This hands-on data from extrusion lines, analytical labs, and the unforgiving scale of solution reactors offers more than catalogue assurances.

    Continuous Testing and Real-World Data

    Theory rarely holds up without hard-nosed verification. Regular side-by-side testing against international and local standards forms the backbone of our production process. Some customers request full spectra for every lot, others just a certificate and the drum. Either way, our reputation follows the physical product, not just a report. Our in-house lab team, many of whom started on the actual plant lines, understand the minute process tweaks that appear trivial on a spec sheet but balloon into multi-day shutdowns in reality.

    Feedback: Correction, Not Hype

    We treat complaints as production assets. In the early years, more than one large dye house flagged solubility variability, only for us to uncover solvent residues in a new drier we had commissioned. That learning found its way into every subsequent shipment form, and we changed the way we verified lot transitions. The best optimization stories come from these unplanned hurdles. Open communication channels, on-site troubleshooting, and a willingness to tweak at scale turn complaints into technical steps forward.

    The Future of Manufacturing for 2-Aminophenol

    Quality standards evolve, not because paper requirements change, but because the chemistry used on the other end of the supply chain advances. We maintain constant dialogue with end-user R&D teams and technical groups—tracking regulatory changes, green chemistry trends, and new analytical protocols. Recent industry shifts push toward lower residual aniline thresholds and demand for environmental data tracking. We interpret these not as table stakes, but signal flares for real process change—sometimes reworking core steps, integrating in-line monitoring, or replacing long-used solvents after decades. Customer needs do not follow fixed playbooks; we keep expertise close to the process floor to adapt without losing production rhythm.

    Sourcing and Supply—Navigating Global Fluctuations

    Sourcing aniline and nitrite reagents from trusted vendors weighs on our management daily. The practicalities of bulk chemistry mean raw material shortages, transport hiccups, or new customs regulations have broad ripples. Over time, multi-year partnerships with upstream suppliers cut through most surprises, yet the relationship rests on honesty: delays, quality deviations, or packaging errors do not remain hidden. Each market wave prompts supply chain reviews, secondary vendor vetting, and sometimes investment in on-site stockholding above just-in-time needs. The direct result: the stability of our 2-Aminophenol deliveries—even in peak demand cycles—often wins loyalty more than marginal price discounts ever did.

    Environmental Awareness: Waste, Water, and Sustainable Operation

    Manufacturing 2-Aminophenol carries environmental duties beyond the fence-line. A large portion of process development time—sometimes entire fiscal quarters—spends on effluent reduction, water recycling, and safe waste neutralization. We learned hard lessons years back when a spike in biological oxygen demand flagged by the local authority forced rapid process overhaul. The investment in advanced wastewater treatments, regular soil and water monitoring, and employee-led green initiatives did not simply meet compliance. They preempted later headaches and built trust with both nearby communities and buyers auditing for sustainable sourcing.

    Practical Partnership: Supporting Downstream Process Needs

    Every buyer of 2-Aminophenol expects a foundation of quality, but it’s the immediate support that usually matters most. We offer detailed dissolution comparisons, particle testing, and on-call troubleshooting teams. R&D chemists regularly ship us their blends to run on our own pilot reactors, not just to sell more but to catch incompatibilities before they scale. In one case, a client’s unique pH tolerance surfaced as a latent yield killer—solved within the week after reworking one precipitation step on our line. These collaborations save vendors hidden costs and avoid downstream equipment fouling or lost batches.

    Managing Change: Regulatory Shifts and Rapid Adaptation

    Across the last decade, regional rules on chemical composition, residual contaminants, and safety classification of 2-Aminophenol have sharpened. Delays in adapting destroy more than revenue—they eat into reputation. By keeping regulatory advisors inside our main decision-making, we gained agility as new REACH or FDA expectations came up. No process change happens in isolation. We test, document, and communicate shifts, involving customers early. Customers facing audits or new market entries feel the value in cleared paperwork and batch certifications under reformed rules.

    Differentiating with Data, Not Just Promises

    In practice, many buyers separate reliable supplies from cost-led commodity offerings by the thoroughness of data support. We never shy from sharing process maps, impurity profiles, and analytical reports—carefully protecting proprietary steps but building buyer confidence. Open data tracks win more repeated business than slogans. Transparent technical facts, demonstrated after months of pilot batch feedback, build robust partnerships. We encourage customer audits and performance reviews, making sure every number matches practical use, not just paper theory.

    Technical Backup: Analytical, Pilot and Scale-up Support

    Most buyers who move from lab to pilot scale run into questions about scale-responsive reactivity or unexpected byproducts. Recognizing this, we maintain scaled reactor setups, offering test runs under real-world conditions. Analytical data flows straight from these runs to customers, who often spot fine points that textbook batch testing misses. Some of the best improvements—a more rapid crystallization, reduced oxidation potential, or easier separation—come from these on-the-ground collaborations, not from catalog literature.

    The End-User Difference: Listening and Adapting

    The day-to-day language of global manufacturing carries its own rhythm. Where traders talk in volumes and shipment cycles, we talk in deviations, downtime, and real chemical applications. End-users—who see lab mishaps or batch failures up close—bring questions and requirements rooted in reality. Every hour spent on their process floors, every lot tested under their actual conditions, brings us closer to practical improvements. We keep this focus central, resisting the temptation to drift too far into hype or abstract marketing.

    Risk Management: Beyond Traditional Quality Control

    Any large-scale chemical operation juggles risk: accidents, market shocks, or legal exposure. We see enterprise risk control not as a compliance checkbox but as an active, shifting reality. Multi-stage QA audits, cross-department process reviews, and regular safety walkdowns build institutional memory. When either the product or surrounding market threatens disruption—such as an unforeseen supply interruption or customer recall—practice counts. Experience teaches flexibility; response plans change, backup lots clear, and transparency always takes priority over blame.

    Why We Keep Making 2-Aminophenol Despite Shifting Markets

    Markets change—raw material costs swing, regulatory standards tighten, and buyers chase lower offers. The reason we continue to invest in 2-Aminophenol is not habit, but clear technical value. This product occupies crucial space in specialty chemistry. No near-term replacement duplicates its reactivity or cost-advantage in metal-complex dye and pharma synthesis. Our experience shows demand for rigorous, repeatable, and traceable product—even as cheap substitutes filter into the market—remains robust. Buyers who value end-to-end control know the difference in day-to-day usage.

    Building Toward Sustainable Operation and Partnerships

    We aim beyond daily production metrics, focusing efforts on responsible operation and real results for partners. While trends point to greener chemistry and digitalized batch tracking, core practical issues—consistency, direct technical support, environmental stewardship—anchor every process step. Manufacturing 2-Aminophenol ties us both to the chemistry community and to those who count on reliable transformer products in downstream industries. By placing staff, partners, and application scenarios at the center of process development, we continue not just as suppliers but as full partners in specialty chemistry’s evolving story.