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HS Code |
130176 |
| ChemicalName | 2,5-Xylenol |
| CASNumber | 95-87-4 |
| MolecularFormula | C8H10O |
| MolecularWeight | 122.16 g/mol |
| Appearance | White to pale yellow crystalline solid |
| MeltingPoint | 57-59°C |
| BoilingPoint | 210-212°C |
| Density | 1.04 g/cm3 |
| SolubilityInWater | 1.38 g/L at 25°C |
| FlashPoint | 87°C (closed cup) |
| Odor | Phenolic |
| pKa | 10.22 |
| VaporPressure | 0.15 mmHg at 25°C |
As an accredited 2,5-Xylenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 2,5-Xylenol is packaged in a 500 mL amber glass bottle, sealed with a screw cap, and labeled with safety and hazard information. |
| Shipping | 2,5-Xylenol should be shipped in tightly sealed containers, protected from physical damage and moisture. Transport in compliance with local, national, and international regulations for hazardous chemicals. Label containers clearly with hazard information. Store upright, away from incompatible substances, and ensure good ventilation during transit to minimize vapor buildup and risk of exposure. |
| Storage | 2,5-Xylenol should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from sources of heat, sparks, or open flames. Keep it away from strong oxidizing agents and acids. Store at room temperature and protect from direct sunlight. Use appropriate secondary containment to prevent spills and ensure containers are clearly labeled. |
Applications of 2,5-Xylenol in Industrial ManufacturingAs an established primary producer, we supply high-purity 2,5-Xylenol for demanding sectors where reliability in formulation, process performance, and product quality are paramount. Our technical team ensures customers receive material engineered for precise industrial integration. Below, you will find detailed examples of how our product supports specialized downstream manufacturing worldwide. 1. Synthesis of Agricultural Fungicide IntermediatesMajor agrochemical manufacturers use 2,5-Xylenol as a core intermediate for synthesizing essential active agents in fungicide production. The phenolic structure of the molecule allows targeted substitution reactions to generate specific methylated phenol derivatives, supporting scalable synthesis of modern pesticides with high field stability. Manufacturing sites incorporate the raw material directly into multi-step coupling and cyclization reactions under controlled temperature and pH conditions, ensuring purity profiles that meet demanding global agrochemical regulations. Industry compliance standards
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2. Manufacture of High-Performance AntioxidantsAntioxidant formulators in the polymer and rubber sectors use 2,5-Xylenol to build sterically-hindered phenolic stabilizers, which protect high-value materials from thermal and oxidative degradation. Our material enters proprietary condensation and alkylation routes, integrating at the monomer level to deliver consistent quality and performance. Accurate dosing ensures finished antioxidants meet tight melt-point and solubility specifications required by automotive, footwear, and electronics customers. Industry compliance standards
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3. Formulation of Phenolic Resins for Industrial CoatingsCoatings and resin manufacturers employ 2,5-Xylenol to engineer phenolic resins with tailored cure profiles and adhesion properties. The material’s methyl substitution affords precise control over resin cross-linking and solvent resistance—particularly important for industrial baking enamels, can coatings, and fast-dry primers. Integrators leverage our stringent quality controls to achieve batch-to-batch consistency in high-shear mixers and reactor vessels, supporting stringent coatings performance claims. Industry compliance standards
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4. Production of Pharmaceutical Preservative IntermediatesOur 2,5-Xylenol is engineered for pharmaceutical-grade synthesis, supplying active intermediate manufacturers with a purified phenolic precursor for parenteral and topical preservative systems. Pharmacopoeial QC ensures absence of critical impurities and consistent specific gravity. Production teams apply this material in targeted methylation and halogenation reactions—minimizing side-chain formation and optimizing yield, in compliance with GMP and pharmacopeia standards. Industry compliance standards
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5. Synthesis of Industrial Dye IntermediatesDye houses and pigment makers utilize 2,5-Xylenol as a key precursor in azo and anthraquinone dye synthesis. The positional methylation enables the construction of high-fastness chromophores for textile, leather, and plastic coloration. Our precise QC and lot traceability provide pigment manufacturers with confidence in hue control and consistency across large-scale batches, supporting integration with sulfonation or diazotization routes under high-shear conditions. Industry compliance standards
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6. Production of Specialty Lubricant Additives2,5-Xylenol functions as an essential building block in the synthesis of phenolic additives for high-performance lubricant formulations. Its structural reactivity enables oil-soluble antioxidants suitable for blending into industrial and automotive lubricants with elevated thermal and oxidative stability. Production lines implement our product in clean-room alkylation, ensuring controlled side-product levels and compatibility with base oil systems. Accurate dosing and in-process QC support formulating blenders in meeting demanding OEM and device manufacturer requirements worldwide. Industry compliance standards
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Producing 2,5-Xylenol starts with careful attention to both raw materials and process control. As a chemical manufacturer, we see every batch as an opportunity to reinforce our standards. Unlike traders who touch only finished goods, we shape the starting materials, chart every heating stage, measure each purification step, and stand behind the consistency of the end product. Our hands-on approach drives the reliability chemists expect once this intermediate reaches their hands.
We manufacture 2,5-Xylenol with a focus on purity and payload, since unnecessary impurities disrupt downstream chemistry and put plant safety at risk. Laboratories and plants relying on 2,5-Xylenol for intermediates notice these differences, even if they can be hard to quantify on a simple data sheet. For us, the product leaves our site only after it crosses a certain threshold in GC analysis—not just at a single time, but every cycle, every batch. Trusted reputation in the chemical world depends on more than a single test; it takes years of repeat quality and transparency.
The 2,5-Xylenol we supply carries our internal model code, but users care about core details: molecular formula C8H10O, CAS 95-87-4. Most of our output ranges above 99.0 percent purity by gas chromatography, as lower purities can introduce interference in applications. The melting point lands between 116 and 118°C, and those few degrees matter when downstream temperature control is strict. Density sits at around 1.05 g/cm³ at 25°C. We bottle in drum, steel container, or bulk tank depending on regular demand and project scale.
Packing for 2,5-Xylenol is always evaluated with practical shipping risks in mind. Leakage costs too much—not only lost material but also time and possible environmental damage. We never leave secondary containment and transport stability as afterthoughts. Over decades, we’ve seen how inadequate drum materials, seal failure, or careless stacking can lead to costly spillage on arrival, which leaves lasting impressions that quality assurance can't mend with just an apology.
2,5-Xylenol stands as a key intermediate, with its placement of methyl groups and hydroxyl ring making it far more than a laboratory chemical curiosity. The shape and reactivity attract the agrochemical industry, where it finds utility in synthesizing specific crop protection agents. Anyone who works in chemical process design knows how finicky aryl intermediates can be—2,5-Xylenol resists side reactions better than many close analogs, giving more predictable results and easier downstream purifications.
In the world of polymer developers, 2,5-Xylenol's ortho-para substitution pattern offers a stable building block, encouraging chain growth reactions or specific cross-linking without inviting excessive branching. Phenol resins derived from 2,5-Xylenol bring particular toughness and heat resistance—attributes easily traced back to the clean feedstock. We hear directly from plant technicians when variations affect curing profiles of their batches. This feedback keeps our team focused on reliable composition.
Developers in pharmaceuticals pursue 2,5-Xylenol for advanced intermediates. Its precise pattern lets process chemists append other substituents, targeting molecules they cannot reach from the more common phenol or cresol feedstocks. Demand from this sector rises and falls with innovation cycles, but requests for extra impurity profiling or packaging in glass always signal experiments that matter. We take the responsibility to meet those needs seriously, and avoid substituting batches without thorough disclosure.
Most users at scale know the practical distinction between 2,5-Xylenol and its isomers, such as 2,4-xylenol or 2,6-xylenol. The placement of methyl groups on the benzene ring—two units apart as in 2,5-x versus neighboring as in 2,4-x—translates to real-world effects on reactivity, solubility, and downstream product structure. Experienced chemists choose 2,5-Xylenol where thermal and chemical stability balance with the need for controlled substitution elsewhere on the ring. Shortcuts cost more than they save; using cheaper isomers as substitutes often results in lower yields or costly reprocessing.
Differences surface in melting point profiles, color stability, and storage sensitivity. For example, 2,6-xylenol often brings a lower melting point and higher volatility, which influences process engineers during plant operation. Over the years, we’ve seen downstream users forced to redesign steps or adjust solvent mixes after shifting away from true 2,5-Xylenol. Such forced adaptations usually cost time that can’t be recovered. Mistaking one isomer for another based on paperwork rather than firsthand inspection leads to lab and plant frustration—something we work hard to avoid by tracking every batch back to its original synthesis lot.
Packing methods, too, differ subtly for xylenol isomers. 2,5-Xylenol demands careful temperature control in all seasons, as caking or partial melting during humid storage can create measurement errors and loss of product. Our team learned the hard way how small lapses in warehouse AC maintenance cause issues—monomers that cake together hurt downstream measurement and make clean transfer a challenge. Prompted by this, we shifted storage approaches years ago, specifying appropriate temperature bands and clearly labelling all drums with required storage instructions.
Years in chemical production teach lessons that reach beyond reference manuals. Early on, we relied heavily on supplier purity certificates, which seemed complete until a few color complaints and sticky drums surfaced. Analytical routines expanded quickly—GC, HPLC, melting point, water content, and trace element analysis all became non-negotiable. Just a few batches with high impurities create headaches, so tightening controls is a daily commitment. Nobody wants customers tuning their reactors mid-plant run just to accommodate a slightly off-standard batch.
Our production teams walk every lot through round-the-clock checks. Anything falling outside agreed limits triggers batch hold and root cause review—usually before the drums leave the packing area. Emphasis on real-time monitoring matters more for phenolic compounds because oxidation and slight byproduct formation happen surprisingly fast once exposed to air and light. Packaging follows controlled, inert conditions, so that every container opened at a partner’s site reflects what left our floor, down to the color and crystal structure.
Raw material selection in 2,5-Xylenol production quietly shapes end-user experience. Low-quality feedstock bumps up minor byproducts—chlorides or traces of toluene derivatives—which eventually work their way into coatings, resins, or pharmaceutical intermediates. Over the years, we’ve worked to strengthen raw supplier screening, even if that means higher input costs. The gain in batch purity and reliability makes the initial investment worthwhile.
Shipping specialty chemicals can’t take shortcuts. A few years back, reports of loose caps and underfilled drums sparked an overhaul. Unstable containers in long-haul transit, especially at seasonal temperature extremes, led to costly on-site cleanup at customer storage. Today, our 2,5-Xylenol logistics include tamper-evident seals, secondary bundling, and regular audits at every handoff. Staff at transit points receive training on both routine inspection and emergency response.
Customers working at plant scale want just-in-time delivery to minimize storage risk, so shipments go out on a strict schedule. Unpredictable climate adds challenges, so we build buffer time into all transit plans. Our logistics team coordinates so customers never face a production halt waiting on raw materials. Regular feedback from partners gives us headlines: a missed shipment can delay not just one stage but a whole cascade of operations. The back-and-forth communication and ability to triage real issues—no matter when they arise—makes a bigger difference than any stock list or brochure.
We work with container suppliers to select gaskets that resist phenolic compounds specifically. Several years ago, we found subtle incompatibility between common rubber types and 2,5-Xylenol; slow leaching contaminated the contents. After testing and switching to PTFE-lined seals, complaints vanished. This kind of direct feedback cycle happens only when a manufacturer owns both the problem and the solution—an approach hard to find with indirect supply chains.
Handling phenolic intermediates creates risks, so priorities always include worker safety and waste minimization. Our plant setup includes continuous air scrubbing at production and packing points. This prevents low-level phenol fumes from escaping, a critical step as they pose health risks and unpleasant odors. Investing in better ventilation draws from direct experience; the subtle discomfort of spending hours near packing lines made this upgrade an obvious step years ago.
Waste treatment practices play a central role. A decade ago, simple solvent flushes sufficed, but as regulations and stewardship standards toughened, we installed multi-stage scrubbing and incineration. The change came partly after neighbor feedback—offsite odors after rainfall signaled incomplete neutralization. Now, we recycle or incinerate byproducts before releasing any water or air effluent. Manufacturing accountability drives long-term relationships and protects the workers who rely on us.
Packaging improvements contribute to sustainability as well. By moving away from single-use drums and introducing reusable tote options, we cut down on landfill waste and lower shipping costs over the project lifecycle. Direct requests from customers looking to shrink their environmental footprint push us to test new containers and collection programs, including rinsing stations and closed-loop returns.
We focus equally on safe handling instructions and support materials, sharing incident histories with new users and updating our partners with any change in process. While chemical plants often compete fiercely on cost, we’ve found reputation grows from open conversation about safety routines and adjustments—sometimes inspired by mishaps, but more often from staying ahead of trouble before it hits.
The best adjustments come from end users. Over years in the field, patterns become clear—certain coatings firms prefer a slightly finer crystal, pharmaceutical partners request extra screening to reduce trace organics. Trends in requests help us predict where our customers’ industries are heading. Last year, repeated questions on melt blockages prompted a review of our drying process and tighter control on moisture content. Updates were rolled out in production not from market research, but from direct, honest ongoing conversations with users.
We also host annual sessions at our facility where users walk the line, see the actual steps, and offer their perspective. This feedback—what matters on their side of the pipeline, what we could adjust—grows more nuanced each year, and shapes both short-term fixes and future investment. Several partners have pointed out how supply surges or shortages elsewhere highlight the value of having a manufacturer truly tuned to changing requirements. Large-volume projects often involve joint planning for inventory management and forecasting, which helps both sides avoid costly surprises.
Continuous improvement runs deeper than published standards. Internal review after off-spec batches or delivery hiccups generates not just reports, but training adjustments and equipment upgrades. For instance, installing a second redundancy circuit on our chiller system came after a one-off blockage incident. The upfront cost saves time and trust—elements even more valuable than daily production throughput.
The landscape for advanced phenolic intermediates like 2,5-Xylenol grows more dynamic every year. End-users are prioritizing traceability—knowing not just what’s in the barrel, but where each gram comes from, how it was made, and who certified it along the way. Automation in production and analytics, while valuable, can’t fully replace the role of a hands-on team. The repeated tweaking and human inspection give the reliability major plants depend on. Some shifts toward greener chemistry promise lower emissions and resource use down the line; already, we’re exploring new catalyst systems and waste heat recovery based on customer demand and evolving standards.
Formulators ask more often for detailed impurity breakdowns, driven by tighter pharmaceutical and electronics specifications. This change means manufacturers must invest consistently in better analytics and documentation. Over the past year, we’ve upgraded our in-line monitoring, worked with partners to build shared audit trails, and rolled out more transparent tracking. While this raises costs, it also builds trust—the kind that shields partners from regulatory surprises or performance issues down the line.
Smaller-batch and specialty users now look for custom packaging, longer shelf life, and assured change-management protocols. Our own facility now blocks out reserve production hours for these smaller but often high-value projects. By listening directly to production partners, batch engineers, and R&D labs, we keep pace with industry needs and respond faster than slower-moving distributors or resellers.
Beyond current processes, we’re investigating bio-based routes to 2,5-Xylenol, aiming to cut dependence on petroleum feedstocks. While still at pilot stage, preliminary yields look promising and early stakeholder visits highlight how much value this shift could unlock for brand-conscious end users—especially in the specialty chemical and pharma space. Such transitions only succeed when built on solid foundations of quality, reliability, and transparent performance metrics, all anchored in the day-to-day understanding of production challenges and end-user needs.
For users downstream, working directly with the source offers more than price advantages. Real-world chemical production doesn’t always follow textbook patterns. Variations—seasonal, procedural, or packing-related—leave their mark on final results. By engaging with a manufacturer, partners gain early warning of any run changes, access to backup batches on short notice, and the peace of mind that comes from knowing the same team answering inquiries makes and ships the material.
Certifications and extensive documentation only tell part of the story. Site visits, discussions with the plant team, and joint troubleshooting build the kind of connections that outlive staff or contract changes. We’ve spent years exchanging troubleshooting notes, refining joint sampling protocols, and building downtime reporting—not out of obligation, but from seeing how productivity grows when both sides invest for the long view.
Every kilogram of 2,5-Xylenol we produce reflects years of iteration, learning, and direct engagement with problems and their solutions. The process sits at the intersection of chemistry, engineering, and partnership. The trust built through open records, swift reaction to feedback, and investment in safer, more sustainable production sustains both the integrity of our plant and the performance of our partners’ products.
For those seeking reliability, responsiveness, and in-depth technical support, a manufacturer-led approach to chemical sourcing offers clear advantages. The foundation rests not just on technical sheets, but on lived commitment to quality, safety, and ongoing improvement—made visible in every drum, every shipment, and every open line of communication.