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2,4-Dichloronitrobenzene

    • Product Name 2,4-Dichloronitrobenzene
    • Alias 1-chloro-2-nitro-4-chlorobenzene
    • Einecs 202-749-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    982847

    CAS_Number 611-06-3
    Molecular_Formula C6H3Cl2NO2
    Molecular_Weight 192.00 g/mol
    Appearance Yellow crystalline solid
    Melting_Point 66-68 °C
    Boiling_Point 273-274 °C
    Density 1.56 g/cm3
    Solubility_in_Water Slightly soluble
    Refractive_Index 1.603
    Flash_Point 143 °C
    Purity Typically ≥99%
    Synonyms 2,4-DCNB; 1-Nitro-2,4-dichlorobenzene
    EC_Number 210-255-8

    As an accredited 2,4-Dichloronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 2,4-Dichloronitrobenzene is packaged in a 500g amber glass bottle with a secure screw cap and hazard labeling.
    Shipping 2,4-Dichloronitrobenzene is typically shipped in tightly sealed containers to prevent leaks and contamination. It should be labeled as hazardous material, protected from heat, moisture, and incompatible substances. Transport must comply with local and international chemical safety regulations, ensuring proper documentation and handling to minimize exposure risks during transit.
    Storage 2,4-Dichloronitrobenzene should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers and reducing agents. Protect from direct sunlight, heat, and moisture. Ensure proper labeling and keep away from sources of ignition. Use appropriate secondary containment to prevent environmental release in case of spills.
    Application of 2,4-Dichloronitrobenzene

    Applications of 2,4-Dichloronitrobenzene in Industrial Manufacturing

    2,4-Dichloronitrobenzene serves as a critical nitroaromatic intermediate for several specialized sectors, supporting synthesis workflows in regulated downstream production. Our direct manufacturing expertise ensures that every supply batch meets industry-driven requirements for formulation, processing, and final product consistency. Below, we detail actual industrial applications across chemicals, pharmaceuticals, and pigment manufacture, with clear information on standards, ratios, processing steps, and end-use products.

    1. Synthesis of Agrochemical Active Ingredients (Herbicides)

    Large-scale herbicide manufacturing relies on this raw material for the preparation of chlorinated aniline derivatives, which act as building blocks for selective weed control compounds. Chemical plants use this intermediate for multi-step transformations, enabling precision engineering of proprietary agroactive molecules under controlled safety and quality systems.

    Industry compliance standards

    • ISO 9001 Quality Management
    • REACH Registration (EC No. 1907/2006, Annex IX–herbicidal substances)
    • FAO/WHO International Code of Conduct on Pesticide Management
    • China GB 20810–2006 (Quality standard for technical herbicide)

    Typical usage ratio

    • 6–12% of total reaction mass, adjusted based on the chlorination stage requirements, target herbicide structure, and downstream conversion efficiency

    Downstream process integration

    • Batchwise or continuous introduction after raw base neutralization, followed by reduction and amination steps to access chloroaniline intermediates
    • Quality control checkpoints for residual nitroaromatics prior to condensation or coupling reactions

    Final product types

    • Selective pre-emergent herbicides (e.g., Pendimethalin, Trifluralin technical concentrate)
    • High-purity active ingredient for suspension concentrates and emulsifiable concentrates

    2. Production of Dyes and Pigments (Azo and Disperse Dyes)

    Textile dye manufacturers use this compound as a key nitro precursor for diazo coupling processes, particularly in the development of high-stability azo dyes and solvent-resistant disperse pigments. Its chloronitro structure gives unique chromophoric properties, supporting vivid color shades and resistance profiles demanded by regulated clothing and plastics sectors.

    Industry compliance standards

    • Oeko-Tex® Standard 100 (for textile auxiliaries)
    • EN 71-3 (Toy Safety – migration of certain elements for pigments)
    • ZDHC Manufacturing Restricted Substances List (MRSL)
    • ISO 105-C06 (Textiles–tests for color fastness to domestic laundering)

    Typical usage ratio

    • 4–10% relative to total coupling agents, ratio varies for target dye concentration, desired color strength, and final hue intensity

    Downstream process integration

    • Direct addition to nitrobenzene conversion reactors for reduction to corresponding anilines, which then enter diazotization or coupling reactions
    • Intermediate purification steps to control by-product formation and standardize batch chromaticity

    Final product types

    • Azo dyes for cotton and polyester applications (e.g., Disperse Yellow 54, Solvent Red 24)
    • Heat- and light-resistant pigment dispersions for plastics, fibers, inks, and coatings

    3. API Intermediate for Pharmaceutical Synthesis (Paracetamol and Related Drugs)

    Pharmaceutical API plants rely on this chemical as a chlorinated nitrobenzene intermediate during the multistep synthesis of paracetamol analogues and certain antipyretic-amino drugs. The material’s high assay specification supports tightly regulated hydrogenation and downstream amination steps, which are critical for API batch integrity meeting pharmacopeia requirements.

    Industry compliance standards

    • ICH Q7A (GMP for active pharmaceutical ingredients)
    • Ph. Eur. and USP monographs for intermediate control
    • China GMP (2020 Revision) for chemical synthesis plants
    • FDA 21 CFR Part 211 (Finished pharmaceuticals)

    Typical usage ratio

    • Up to 7%, typically controlled within 5–7% of the API synthesis batch, depending on yield and purity standards for subsequent reduction and hydrolysis reactions

    Downstream process integration

    • Charged at intermediate stage post-nitration, subjected to catalytic hydrogenation for selective reduction to aminobenzene derivatives, with in-process analytical monitoring for trace chlorinated residues
    • Final batch purification aligned to pharmacopeial specifications before conversion into finished APIs

    Final product types

    • Pharmaceutical intermediate for bulk paracetamol (acetaminophen)
    • Starting block for antipyretic and analgesic active compounds intended for tablet and solution formulations

    4. Manufacturing of Specialty Chemicals for Rubber Accelerators

    Rubber chemical producers convert this compound to substituted anilines, which function as precursors for rubber vulcanization accelerators used in tire, conveyor belt, and industrial rubber processing under hazardous-substance-controlled protocols. The traceable purity of the starting material plays a role in downstream batch uniformity and accelerator performance.

    Industry compliance standards

    • ISO 14001:2015 (Environmental management for chemical plants)
    • EU Regulation 2019/1021 (Persistent Organic Pollutants, Annex I–Aromatic amines)
    • GB/T 23147-2008 (China rubber accelerator quality)
    • REACH (for permitted arylamine compounds in downstream rubber additives)

    Typical usage ratio

    • 8–15% relative to batch mass of base reactants, fine-tuned according to specific accelerator grades and impurity control protocols

    Downstream process integration

    • Feeds into pressurized or catalytic reduction units for aniline conversion, followed by condensation/polymerization to target accelerators like DCB or DCBS
    • Emission control and batch sampling checkpoints for residual organochlorines

    Final product types

    • Primary accelerator chemicals (e.g., N,N’-Dicyclohexyl-2-benzothiazolsulfenamide (DCBS))
    • Specialty performance additives for elastomer compounding in tire, hose, and technical rubber manufacturing

    5. Intermediate for Optical Brightener Synthesis

    This material serves optical brightener manufacturers as a key starting block for benzoxazole-based compounds, integral to formulating agents imparting fluorescence in textiles and paper. Quality-controlled production enables downstream synthesis steps to meet fastness, toxicity, and performance specifications crucial for regulated end-use sectors.

    Industry compliance standards

    • ISO 18314-1:2015 (Analytical color measurement techniques for optical brighteners)
    • EU Regulation (EC) No 1272/2008 (CLP) for classification and labeling of chemical substances in paper and textile auxiliaries
    • OEKO-TEX® Standard 100 (for restricted substances in consumer textile products)
    • GB 28007–2011 (Safety for fluorescent whiting agents in paper and board)

    Typical usage ratio

    • 3–8% of total synthesis batch, varied based on target molecular structure of final brightener and conversion pathway efficiency

    Downstream process integration

    • Introduced at the initial condensation reaction to yield aromatic diamine or diaryl ether intermediates, which are then cyclized to form benzoxazole rings
    • Batchwise filtration and recrystallization to minimize color impurities and maximize fluorescence intensity

    Final product types

    • Optical brightener OB-1, OB-2 for polyester, nylon, and paper
    • Fluorescent whitening agents for laundry and pulp processing

    6. Synthesis of Antimicrobial Agents (Specialty Fine Chemicals)

    Producers of specialty antimicrobials for coatings and polymer additives use this nitro compound as a platform for further functionalization reactions. Its chlorinated structure allows streamlined access to biocidal moieties that demonstrate stability in aggressive industrial environments.

    Industry compliance standards

    • BPR (EU Biocidal Products Regulation, Regulation (EU) 528/2012)
    • US EPA Antimicrobial Pesticide Registration (FIFRA standards)
    • GHS SDS (Globally Harmonized System–biocide hazard classification)
    • ISO 22196:2011 (Measurement of antibacterial activity on plastics/surfaces)

    Typical usage ratio

    • 5–11% by formulation batch, tweaked according to target antimicrobial spectrum and surface compatibility of downstream product

    Downstream process integration

    • Feeds into substitution or reduction reaction modules where the aromatic ring forms the backbone for biocidal side chains, followed by formulation into polymer masterbatches or coatings
    • QC analytics deployed for residual nitro/chloro functionality and biocidal efficacy in the final matrix

    Final product types

    • Antimicrobial masterbatches for plastics
    • Bacteriostatic coatings for industrial equipment and public-use surfaces
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    More Introduction

    2,4-Dichloronitrobenzene: From Manufacturing Floor to Industry Backbone

    Introduction

    The industrial world relies on compounds like 2,4-Dichloronitrobenzene to power everything from basic chemical synthesis to advanced agrochemical solutions. Working here at the production end, we see this substance move through its journey—raw materials, transformation, inspection, and packing—before landing on customer benches, ready for application. For many outside the chemical sector, it’s easy to miss how a single small-molecule aromatic like 2,4-Dichloronitrobenzene underpins entire value chains. But inside our plant, every bag and drum represents chlorination and nitration steps done right, each batch representing the cumulative result of hard-won experience and process refinement.

    Our Product: Model, Form, and Consistency

    We manufacture 2,4-Dichloronitrobenzene as a crystalline powder, with consistent pale yellow coloring and a sharp, recognizable odor. Our production uses high-purity chlorobenzene as a base, subjecting it to controlled nitration, thereby achieving tight control on isomer content. Ensuring the consistency of 2,4- over 2,6- isomer ratios marks the difference between commodity outputs and specialty batch quality. Staff on our line know that even minor process shifts—temperature, agitation rate, pH, and dosing speed—affect isomer distribution, and this expertise doesn’t get replaced by automation. Final purity averages above 99%, with each lot verified using in-plant GC and titration. Moisture and contaminant monitoring operates at all scales: minor spikes trigger operator intervention long before quality would fall outside the range that professional applications can accept.

    Our typical product ships in 25 kg woven bags, with drum options at higher volumes for major accounts. These formats help maintain stability and minimize risk of degradation. Over the years, we’ve learned that some customers want even stricter lot traceability, so we offer digital lot histories compiled in our plant, tying back every shipment to source batches, production data, and date of packing. Recognizing that physical integrity matters as much as chemical purity, we use packaging resistant both to mechanical stress and moisture ingress, based on real shipping environments rather than textbook standards.

    Applications: In-House Experience Supporting End Use

    On our side, 2,4-Dichloronitrobenzene usually leaves the plant for two groups: chemical manufacturers focused on downstream synthesis, and agrochemical companies expanding herbicide lines. In the pharmaceutical sector, this compound serves as a precursor for various APIs. Chemists, development teams, and production lines depend on our product’s stability and batch reproducibility, which affect both output quality and process economics. Having worked with clients from the very foundations of their process scale-ups, we’ve seen how this one intermediate takes on value—no matter if the project is a decades-old pesticide factory or a small molecule R&D line at a new bio-plant.

    Most users transform 2,4-Dichloronitrobenzene through reduction, substitution, or cross-coupling reactions. Its chlorine groups present ideal handles for selective activation, while the nitro group opens the door for transformation either by catalytic or chemical reduction. In laboratories, process chemists prefer our material for its predictable purity, which they can trust to behave through multiple processing stages without introducing off-spec waste or introducing problematic side-products. Plants carrying out hydrogenation or nucleophilic substitution appreciate our consistency—because impurities at the starting line always show up as contamination, poor yields, or equipment fouling down the process. Drawing on regular feedback from reactors both large and small, we adjust our control methods when even rare problems appear, like trace isomer drift or residual acid contamination.

    Practical Manufacturing Considerations

    From our years of manufacturing, the handling and safety profile of 2,4-Dichloronitrobenzene remains a recurring theme. Most experienced handlers already know not to underestimate its toxicity and the need for controlled environments. We designed our production lines for both worker safety and environmental compliance, eliminating open transfers and maximizing closed handling right from the synthesis stage. Our floor workers monitor for fugitive emissions, skin contact risks, and storage hazards. Each year brings tighter regulatory pressures, and it falls to us to keep quality and safety moving in step, not just for ourselves, but for any customer downstream, who must demonstrate traceability and compliance.

    In every batch, trace dioxin levels draw our attention, and even though no regulatory push exists in some markets, our internal controls address it regardless—because customer trust grows slowly, but a single misstep sets whole shipments back. Having come up through the old days, when manual inspection set standards, we supplemented time-earned skill with modern analytics—HPLC, multi-point sampling, and bench-top MS—to ensure our customers avoid regulatory grief two years down the line.

    Comparisons: What Sets 2,4-Dichloronitrobenzene Apart

    Side-by-side with related compounds like 2,6- or 3,4-Dichloronitrobenzene, 2,4- shows distinct reactivity and isolation properties. Most plants—ours included—anchor their production to this isomer because of its higher demand footprint and wider end-use acceptance. During synthesis, any drift in reaction parameters can produce off-isomers, which do appear in some commercial feeds—especially from older or hastily scaled equipment. The real manufacturers get to know these differences not in catalog pages, but in pilot batches and QC tables: 2,4- runs cleaner through downstream chlorination and reduction than the 2,6- or 3,4- variants, meaning fewer headaches at scale.

    Compared to simple nitrobenzenes or monochloro-substituted families, the dual chlorine-anchored aromatic system in 2,4-Dichloronitrobenzene lends a balance of reactivity and feedstock stability. End users confirm that it stands out for its dual use: both as a halogen source for nucleophilic substitution and as a pre-built nitroaromatic for reduction chemistry. We observe customer projects needing cleaner reactions and fewer side-steps than those relying on less pure isomers or less tightly controlled materials. These differences grow larger during process upsets, when off-spec isomers throw downstream yields—and costs—out of line.

    Quality Control and Traceability in Real Practice

    Inside production, lab and shift teams continually debate where QC ends and production begins. True quality doesn’t come from inspecting finished goods alone; it starts with making the right choices in solvent recovery, feedstock sources, and reaction control. Our QC teams sample across the batch, and full traceability trails follow every kilogram out the door. Over the years, customer audits opened our eyes to the small details: batch traceability down to operator level, records for each pump cycle, solvent lots, and equipment cleaning logs. More than one customer built entire regulatory submissions on the back of those records, which keeps us accountable.

    Investing in robust analytical platforms—especially GC-MS for trace impurities and HPLC for isomer allocation—costs in the short term, but saves shipments and relationships in the long term. We often run deeper impurity profiles than required on paper to satisfy our engineers’ need for assurance. Customers from pharmaceuticals sometimes ask for extended impurity sheets, with documentation signed by the lab supervisor: we provide these readily, because the consequences of hidden variation show up not only in rejections but in customer downtime, recalls, or expensive reruns. Our analytical routine includes not just snapshot sampling, but retention samples for every lot, held under controlled conditions, ready for reanalysis if questions arise farther down the timeline.

    Challenges and Hard Lessons Learned

    Manufacturing 2,4-Dichloronitrobenzene doesn’t reward shortcuts, either in sourcing or process. Cheap intermediates often tempt production teams, but that path leads to headaches down the line—whether in equipment fouling, filter blinding, or off-color product rejections. We learned, sometimes the hard way, that savings up front turn into cost increases through lower yields and higher waste disposal. Downstream end-users—especially those pushing for pharma or high-end agrochemical applications—make their own process decisions based on data integrity and historical quality, not price spread in the open market.

    Plant maintenance, raw material pricing swings, and skills retention play larger roles than most outsiders realize. During raw material price spikes, pressure grew to cut corners or source from new vendors—every substitution introduced new risk. Only years of experience, with records to back it up, protect long-term quality and customer confidence. Our senior operators, many with decades on the line, enforce these standards by mentoring new hands, teaching them to never let today’s efficiency undermine next quarter’s trust.

    Shipping and storage conditions matter, too. We switched up packaging after a few incidents—longer transport in humid months showed problems with clumping and offline color shifts that standard packs just couldn’t prevent. From these lessons, we adopted foil-lined sacks for higher risk shipments and invested in climate-controlled warehouses, despite higher overheads, after seeing first-hand how they dampened complaint calls and product loss during seasonal peaks.

    Moving Forward: Customer Partnership and Industry Trends

    As end-users demand more transparency and documentation, our plant invests in both digitized records and customer-facing reports. Modern regulatory frameworks—such as those for REACH or local environmental registries—expect not only purity assurance but full traceability. We keep records accessible, both for downstream audits and for customers seeking assurance that their own compliance doesn’t depend on guesswork. The dialog between line staff, QC, and customer reps keeps us sharp; with each new project, we deepen our understanding of real-world applications and process demands on every shipment of 2,4-Dichloronitrobenzene leaving our doors.

    Innovation in production now grows not just from equipment upgrades, but also operator skillsets. We upskill with regular in-house workshops, pushing our team to keep up with green chemistry trends, energy use reduction, and environmental safety advances. Process redesign—a topic that comes up every cycle—looks for both cost improvements and reduced waste emissions, but never at the expense of performance as proven in customer trials.

    Where customers look for greener, safer alternatives, we collaborate on re-engineering process steps or on developing lower-emission packaging. These partnerships lead to tangible process modifications, sometimes minor, sometimes sweeping; every new regulatory hurdle or customer audit brings lessons directly back to our operating procedures. Our experience as direct producers—not as traders or speculators—gives us a unique perspective on the upstream and downstream impacts of each improvement.

    Looking at the Road Ahead

    We recognize that no commodity stays the same for long. Each year, customer and regulatory requirements change, and new application methods test the limits of traditional chemistry. In response, our production focuses on flexibility and responsiveness: small changes in reaction conditions, quick adaptation to feedstock availability changes, and ongoing operator training. Our team wants each lot leaving the warehouse not only to meet specs, but to reflect incremental improvements over the previous runs. Sharing our accumulated knowledge, both successes and mistakes, with customers and partners remains the engine of our progress.

    Conclusion

    From process management to customer service, making and supplying 2,4-Dichloronitrobenzene means balancing demands—purity, safety, traceability, and responsiveness. We never view this product as just another standard intermediate. Instead, every shift, every adjustment, and every shipment reflects our belief in doing the job right, drawing on collective experience and a willingness to listen to both evolving industry needs and critical feedback from the field. The future of 2,4-Dichloronitrobenzene will keep rewarding those who dig into the process, respect the demands of their customers, and never stop improving, one batch at a time.