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2,4,6-Trichloroaniline

    • Product Name 2,4,6-Trichloroaniline
    • Alias 2,4,6-Trichlorophenylamine
    • Einecs 209-481-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    942273

    Chemical Name 2,4,6-Trichloroaniline
    Cas Number 634-93-5
    Molecular Formula C6H4Cl3N
    Molecular Weight 196.46 g/mol
    Appearance White to pale yellow crystalline solid
    Melting Point 71-74 °C
    Boiling Point 285 °C
    Density 1.56 g/cm3
    Solubility In Water Slightly soluble
    Flash Point 140 °C
    Synonyms 2,4,6-Trichloro-1-aminobenzene
    Pubchem Cid 12138
    Ec Number 211-222-6
    Odor Slight aromatic odor
    Refractive Index 1.65 (estimated)

    As an accredited 2,4,6-Trichloroaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle labeled "2,4,6-Trichloroaniline, 100g," featuring hazard symbols, lot number, and manufacturer’s details; securely sealed.
    Shipping 2,4,6-Trichloroaniline should be shipped in tightly sealed containers, clearly labeled, and cushioned to prevent breakage. It must comply with local, national, and international hazardous materials regulations, such as those set by DOT, IATA, or IMDG. Store and transport the chemical in a cool, dry, and well-ventilated location, away from incompatible substances.
    Storage 2,4,6-Trichloroaniline should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizers and acids. Protect it from moisture and direct sunlight. Clearly label the container, and ensure it is kept away from heat sources or open flames. Follow all local regulations and safety guidelines for hazardous chemicals.
    Application of 2,4,6-Trichloroaniline

    Applications of 2,4,6-Trichloroaniline in Industrial Manufacturing

    We have supplied 2,4,6-Trichloroaniline to multiple downstream sectors as an intermediate with defined technical requirements. Our material is manufactured under strict quality controls to support specialized integration in the production of agrochemical actives, dyestuff intermediates, pharmaceutical precursors, and specialty chemical synthesis. Explore the principal industrial scenarios below, including detailed compliance, processing, and finished product information.

    1. Agrochemical Active Ingredient Synthesis

    Major agrochemical manufacturers incorporate 2,4,6-Trichloroaniline as a critical intermediate during the synthesis of certain triazole and anilide herbicides and fungicides. The compound enters as a chlorinated building block within multi-step reactions that establish the desired aromatic backbone required for selectivity and field stability. Adherence to traceability and impurities profiling is essential throughout this value chain.

    Industry compliance standards

    • FAO/WHO Specifications for Pesticide Products
    • REACH Regulation (EC) No 1907/2006
    • ISO 9001:2015 Quality Management for Agrochemicals
    • OECD Good Laboratory Practice (GLP) Principles

    Typical usage ratio

    • 0.4–0.9 mol per mol of final active ingredient, adjusted based on molecular yield and side reaction control requirements within the intermediate synthesis stage.

    Downstream process integration

    • Integrated as a coupling partner in aromatic substitution and amide formation during the mid-stage synthesis of selective herbicides and fungicides.
    • Undergoes subsequent chlorination or condensation, depending on finished molecule design.

    Final product types

    • Triazole fungicides (e.g., tebuconazole derivatives)
    • Anilide herbicides
    • Pre-emergent weed control actives

    2. Dyestuff Intermediate Manufacturing

    Producers of organic pigments and vat dyes depend on 2,4,6-Trichloroaniline as a targeted amino source during the multi-stage production of complex colorants. The material’s electronic profile supports key diazotization and coupling steps, directly influencing hue stability and tinctorial value in the resultant dyes.

    Industry compliance standards

    • ETAD (Ecological and Toxicological Association of Dyes and Organic Pigments Manufacturers) guidelines
    • OEKO-TEX Standard 100 for textile chemical inputs
    • GB/T 21866-2008 for industrial dye quality in China
    • ISO 9001:2015 for pigment synthesis plants

    Typical usage ratio

    • 30–55% of theoretical amino equivalent in batchwise diazotization processes, with precise metering to balance chromophore development and process color control.

    Downstream process integration

    • Introduced in early-stage diazotization followed by coupling with aromatic compounds to build chromogenic backbones; primary input during vat and disperse dye synthesis.

    Final product types

    • Chlorinated azo dyes for polyester fabrics
    • Vat dyes for cotton textile dyeing and printing
    • Construction colorants and specialty pigment dispersions

    3. Pharmaceutical Intermediate Production

    API manufacturers rely on 2,4,6-Trichloroaniline as a precursor for certain aniline-type pharmaceutical intermediates, mainly within custom syntheses of anti-inflammatory and antimicrobial actives. The selection of this starting material ensures specific substitution patterns, minimizing downstream purification steps and byproduct complexity.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice Guide for Active Pharmaceutical Ingredients
    • USP–NF (United States Pharmacopeia–National Formulary) for intermediate quality control
    • European Pharmacopoeia (Ph. Eur) monographs for controlled impurities
    • GMP Annex 1 (EU) for synthesized intermediates

    Typical usage ratio

    • 0.6–1.0 mol per mol of target intermediate, depending on the complexity of substitution and multistep conversion yield in the specific pharmaceutical route.

    Downstream process integration

    • Employed during key amination and reduction steps in aniline core assembly; further transformed within closed-system operations for API development.
    • Material QC includes in-process HPLC and GC analysis for residual solvent and impurities tracking.

    Final product types

    • Custom pharmaceutical intermediates for NSAID synthesis
    • Precursors for antimicrobial agent APIs
    • Intermediates for antimalarial compound development

    4. Specialty Chemical Synthesis

    Manufacturers of fine chemicals and engineering polymers utilize 2,4,6-Trichloroaniline as a site-selective nucleophile in reactions demanding strict isomeric control, such as the preparation of halogenated aromatic compounds used in lubricants, corrosion inhibitors, and performance monomers.

    Industry compliance standards

    • ISO 14001:2015 for Environmental Management in specialty synthesis
    • REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) for imported/exported specialty chemicals
    • Globally Harmonized System (GHS) for classification and labeling
    • Responsible Care® Management Framework (chemical industry code)

    Typical usage ratio

    • 10–35 wt% in batch or continuous specialty applications, tailored based on the activity of competing nucleophiles and reaction selectivity requirements.

    Downstream process integration

    • Fed into aromatic nucleophilic substitution or step-growth polymerization reactions for selective substitution; typically under controlled temperature and pressure for risk management.

    Final product types

    • Halogenated specialty monomers for high-performance resins
    • Corrosion inhibitor additives for industrial metalworking fluids
    • Intermediates for electronics-grade fine chemicals
    Free Quote

    Competitive 2,4,6-Trichloroaniline prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Introducing Our 2,4,6-Trichloroaniline: Confidence Built On Decades Of Production Know-How

    Experience Shapes Our Quality

    We run reactors every week that produce 2,4,6-Trichloroaniline with a focus on reliability, consistency, and scale. Decades spent at the interface of practical chemistry and demanding client applications have taught us what delivers true value in this sector. Our process engineers understand every step, from the selection of high-purity feedstocks to the final crystallization wash, trimming off those last traces of unwanted isomers. Equipment modifications and reactor design tweaks grew out of our direct production experience. These technical adjustments produce a material that continues to meet real-world needs, not just check boxes in theoretical documents.

    Purity Isn’t Just A Number—It’s What Makes Or Breaks Downstream Applications

    Unlike technical-grade batches common in global markets, our standard material holds a purity well above 99%. Trace monochlorinated or dichlorinated contaminants cause headaches for dye formulators and pharmaceutical chemists. Direct feedback from pigment houses and API manufacturers led us to emphasize the reduction of these impurities during both the chlorination and amination stages. Careful in-process sampling and robust final analysis keep unseen batch-to-batch drift from disrupting syntheses further along the chain. Chemists know that even minute contaminants can introduce color inconsistency or API instability, so the drive for a clear product specification isn’t just sales talk—it grew out of long hours in both plant and lab.

    Physical Form: Free-Flowing, Non-Caking, Ready For Batch Or Continuous Use

    Most orders arrive in a practical off-white to pale yellow crystalline form. Our material resists caking even in humid environments due to subtle control of moisture during drying and packaging. Packing specialists rotate stock thoroughly and manage temperature during bagging. That matters if you’re blending charges for an automated feed system or drawing aliquots in a busy kilo-lab, since clumped material wastes time and leaves room for error with scale-up processes. We have learned that operators prefer a product that pours easily, doesn’t build up static, and can be handled without specialized tools.

    Usage: Where 2,4,6-Trichloroaniline Makes A Technical Difference

    Our primary customers work across the manufacture of specialty dyes, pigments, and certain high-value active pharmaceutical ingredients. The high reactivity of the aniline group, tempered by three chlorine atoms at the 2, 4, and 6 positions, makes this molecule a useful intermediate for coupling and substitution reactions. Binyl, azo, and phthalocyanine platforms often start with our product as a key feedstock. In pharmaceutical research, our 2,4,6-Trichloroaniline offers a streamlined route to complex heterocycles, especially when researchers aim to avoid unwanted positional isomers that would otherwise slow down purification steps. In agricultural chemistry, formulators prefer consistent color and purity in their intermediates, which is where our experience speaks directly to the needs of practical, ongoing processes.

    Our own technical support lab tracks client feedback and application issues. For example, a pigment factory once flagged a subtle off-color in their blue-violet line. Testing showed trace 2,6-dichloroaniline left in our outgoing batch. After isolating the source to a coolant leak, we overhauled equipment gaskets plant-wide. In the next survey, the pigment ran true and the QA team signed off with confidence. These small moments keep us grounded in the real-world impacts of every shipment.

    Difference Built On Process Control—And Real-World Incentive

    It’s easy to declare grade quality or to recite purity numbers; making sure every shipment aligns with a customer’s exact end-use is much more challenging. We avoid the pitfalls of variable solubility and melting points—common among batches sourced from smaller or non-dedicated producers—by standardizing time, temperature, and solvent exchange parameters at each step. Years of pilot studies and scaled production cycles reveal the subtleties in handling—slow addition rates minimize local overheating, and careful agitation stops heavy crystal formation.

    Unlike some generic lots, our 2,4,6-Trichloroaniline holds a melting point that sits tightly between 54-56°C with low-mass balance drift across batches, verified by differential scanning calorimetry. Solubility profile remains predictable, which supports operators during scale-up or process transfer between regions. Impurity fingerprints—something too many overlook—are mapped in our lab with both standard HPLC and custom GC-MS methods established in-house, not simply checked off at a toll laboratory.

    Comparison with bulk-sourced or merchant-traded product shows distinct differences. Many broad-market samples include variable amounts of 2,4-dichloroaniline or even four-chloro derivatives, pushing downstream users to double their filtration runs or increase solvent usage for standard purification. Both routes carry hidden operational costs—downtime, lost batches, and excessive solvent expense. We commit resources to precise raw material sourcing and keep a tight grip on process timelines to overcome these very practical challenges.

    Scale, Volume, And Reliable Delivery

    Running multiple reactors across different lines means our plant supports bulk requirements for continuous industrial production as well as smaller, specialty orders. This scale translates into buffer capacity. If an emergency order comes in because a pigment plant upstream faces unexpected demand, we adjust campaign schedules and divert inventory without missing established commitments. Inventory staff keeps digital logs and physical count up-to-date so logistics interruptions don’t put your production line at risk.

    Packaging teams use industrial-grade LDPE bags double-lined and sealed inside steel drums for protection against atmospheric contamination and rough handling. We track all shipments by lot number and always retain reserve retains of outgoing batches, ready to support any claims or technical troubleshooting. Documentation aligns with public standards, but we supplement with real-world best practices developed over years of direct feedback from end-users. Quick response on supply chain adjustments and raw material sourcing shifts ensures your downstream project stays on-time and on-spec.

    Real-World Compliance And Worker Safety

    Our plant teams participate in regular HAZOP reviews, monitoring both acute and chronic risks associated with handling arylamines containing multiple chlorines. Operators wear chemical-resistant gloves, goggles, and use vacuum-equipped handling tables to keep airborne contaminants within globally accepted limits. Supervisors run random environmental sampling, with routine updates to local regulatory bodies. Our in-house training modules reflect real events—like reducing open transfer steps after a minor spill, or swapping valve types after a sticking incident during a humid season. We invest in engineering controls not just for compliance, but to ensure each package ships without unexpected contamination or unplanned downtime.

    Technical Collaboration And Problem-Solving: It’s Never Just A Batch Number

    Consultation with end-users—often formulators, scale-up engineers, or academics—remains a big part of our day-to-day work. We act on feedback about odd sample reactivity, melting behavior, or residue levels, drawing on our lab team’s deep familiarity with local trends and device calibration. More than once, an issue that looked like a user-side malfunction traced back to a subtle change in our own process: a raw material supplier tweaked drying temperature, setting off slow shifts in impurity spectrum. We audit critical vendors face-to-face and share technical findings transparently—lessons drawn from these interventions have directly improved both product performance and user trust.

    On request, we’ll discuss application-specific modifications, like hydrophobic packaging for river-adjacent plants or pre-dissolved slurries for labs handling small charge runs. There’s no hidden fee for this. Reliable manufacturing means understanding the environment our product lands in, and adjusting accordingly.

    Supporting Research And New Application Development

    Our analytical lab develops internally validated methods suitable for routine in-process analysis—or regulatory submittals as needed by customers branching into new markets. Material supplied for pilot runs ships under strict chain-of-custody with electronic and hard-copy documentation linking back to individual reactor runs. This kind of traceability isn’t just a marketing checkbox; it grew from years responding to regulatory inquiries and industry audits.

    Researchers exploring alternative process chemistry—new dye routes, gridrol replacements, or advanced pharmaceutical synthesis—often rely on our engineering team for feedstock stability data or impurity risk analysis. If a pilot fails, and the cause lands back with us, we stand behind our product, open our records, and commit to corrective action with real-world solutions, not just boilerplate.

    Sustainability And The Next Generation Of Plant Chemistry

    Years operating at scale have shown the industry-wide reality—chemical manufacturing leaves footprints. We focus on minimizing waste streams by optimizing reaction yields, investing in multi-stage water treatment for chlorinated byproduct removal, and recycling process solvents where purity allows. Our waste treatment reports undergo regular independent review and our engineers look for incremental process improvements every campaign.

    Downstream users increasingly ask tough questions: Was this made with minimized energy use? Is there a plan to recapture chlorinated byproducts? We track these metrics and redesign process loops as we see the data. It isn’t hype; it’s the result of years grappling with disposal quotas and evolving client demands for responsible sourcing. Buyers don’t just want a spec sheet—they want proof of responsible stewardship, and as producers we bear that responsibility directly.

    Why Long-Standing Manufacturing Experience Matters

    In a field crowded with brokers, labs, and nameless third-party vendors, direct manufacturing gives us hands-on insight into both production efficiency and end-user headaches. We monitor each stage, log shift notes, and act on fresh data with each run. Our quality control managers have walked the lines, seeing both successful and problematic campaigns—learning where delays creep in and what preemptive steps matter.

    Product reliability grows from experience, not just inherited protocols. We train up our operators, involve technical support in routine meetings, and bring customer concerns all the way up to the plant manager. These aren’t abstract claims. It’s how we avoid disruption when incoming toluene carries an off-spec contaminant; or pivot packaging lines if regional transport sees a surge in humidity or vibration.

    Shifts in legislation or user trend—stricter environmental standards, new application fields, or sudden regulatory bans—don’t catch us flat-footed. We adapt with data, documented change control, and direct, person-to-person troubleshooting. Plant-level expertise ties every lot shipped to a tangible history of decisions, audits, and on-the-ground problem-solving.

    Summary: 2,4,6-Trichloroaniline Grounded In Real-World Manufacturing Reality

    We deliver 2,4,6-Trichloroaniline from the perspective of practical chemistry—a focus shaped not in theory, but from operating lines, balancing technical specs with hands-on user needs. Our strength lies in tight batch control, targeted analytical support, field-tested packaging and logistics, and an attitude shaped by repeated, real feedback from the industries relying on our product. Experience—from tightening up impurity profiles to supporting both troubleshooting and new application development—sets us apart from generic market competition. We approach every order, every challenge, and every partnership with a direct line back to our manufacturing roots. That’s what gives our users a reliable tool, batch after batch, shipment after shipment.