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2,4,5-Trichlorophenol

    • Product Name 2,4,5-Trichlorophenol
    • Alias TCP
    • Einecs 204-428-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    612652

    Cas Number 95-95-4
    Molecular Formula C6H3Cl3O
    Molecular Weight 197.45 g/mol
    Appearance White to light tan crystalline solid
    Melting Point 69-71 °C
    Boiling Point 246-247 °C
    Solubility In Water 250 mg/L at 25 °C
    Density 1.583 g/cm³ at 20 °C
    Vapor Pressure 0.02 mmHg at 25 °C
    Odor Phenolic
    Pka 6.06
    Flash Point 120 °C (closed cup)
    Logp Octanol Water 3.72

    As an accredited 2,4,5-Trichlorophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g of 2,4,5-Trichlorophenol supplied in a sealed amber glass bottle, labeled with hazard symbols and handling instructions.
    Shipping 2,4,5-Trichlorophenol should be shipped in tightly sealed, corrosion-resistant containers, clearly labeled as hazardous material. It is regulated as a toxic substance (UN2020), requiring compliance with local, national, and international transport regulations, including proper documentation. Packages must be protected from physical damage, heat, and incompatible materials during transit to ensure safety.
    Storage 2,4,5-Trichlorophenol should be stored in a cool, dry, well-ventilated area, away from sources of ignition, heat, and incompatible substances such as strong oxidizers and acids. Keep the container tightly closed and clearly labeled. Store in a corrosion-resistant, chemical-resistant container. Use secondary containment to prevent spills. Access should be restricted to trained personnel only, with appropriate safety signage displayed.
    Application of 2,4,5-Trichlorophenol

    Applications of 2,4,5-Trichlorophenol in Industrial Manufacturing

    2,4,5-Trichlorophenol is a strategically significant chemical intermediate with established roles in several specialty chemical sectors. The following are verified industrial applications where this raw material plays a critical function in downstream manufacturing workflows.

    1. Herbicide Intermediate for 2,4,5-T Production

    Downstream agrochemical producers rely on this material as a key intermediate for synthesizing 2,4,5-Trichlorophenoxyacetic acid (2,4,5-T), which has been used as a selective herbicide for broadleaf plant control. The integration of this intermediate into the phenoxyacetic acid family of herbicides demands strict process control and adherence to regulatory purity targets, with trace dioxin content tightly regulated due to legacy health and environmental concerns. Manufacturers formulate batch reactions under sealed, inert conditions to minimize side-product formation. Finished 2,4,5-T semi-products enter dilution, granulation, or emulsifiable concentrate stages for field application.

    Industry compliance standards

    • US EPA 40 CFR Part 180: Tolerances for Residues of Herbicide Chemicals
    • EU Regulation 1107/2009 on Plant Protection Products (historical use)
    • FAO/WHO Joint Meeting on Pesticide Specifications (JMPS)
    • ISO 9001:2015 Quality Management Systems

    Typical usage ratio

    • 80–100% as a primary phenolic precursor, stoichiometric ratios determined by the target yield of 2,4,5-T synthesis; exact formulation adjusted to account for purity, dioxin-free requirements, and molar conversion rates.

    Downstream process integration

    • Enters as the phenol component in alkylation/esterification with monochloroacetic acid under basic catalysis, followed by workup and purification before further transformation into active herbicidal ingredients.

    Final product types

    • Technical-grade 2,4,5-T for large-scale herbicide manufacturing (historical/legacy use)
    • Bulk herbicide intermediates for export (as raw material, subject to local regulation)

    2. Intermediate for Hexachlorophene Synthesis

    Producers of specialty disinfectants utilize this raw material in the controlled manufacture of hexachlorophene, an antibacterial compound historically used in medical and hygiene products. This transformation requires precise chlorination and condensation steps under cGMP production environments. Feedstock selection, including purity and impurity control, directly impacts downstream product safety and biocidal activity. Although many countries now heavily regulate or restrict hexachlorophene in consumer goods, regulated production persists for specific industrial and regulated healthcare settings.

    Industry compliance standards

    • United States Pharmacopeia (USP) Monograph for Hexachlorophene (for medical/regulated use)
    • 21 CFR Part 358—Over-the-Counter Human Use; Antimicrobial Products
    • ICH Q7 Good Manufacturing Practice Guide for Active Pharmaceutical Ingredients
    • REACH Regulation (EC) No 1907/2006 for chemical safety and traceability in the EU

    Typical usage ratio

    • Roughly 70–90% as the primary condensation phenol input; ratios depend on downstream plant capacity, desired reaction scale, and batch purity specifications.

    Downstream process integration

    • Introduced during chlorination/condensation reaction with formaldehyde, followed by purification, crystallization, and drying, prior to micronization or direct formulation into end-use antimicrobial agents.

    Final product types

    • Industrial-grade hexachlorophene powder
    • Pharmaceutical bulk chemicals for restricted medical, surgical scrub, or veterinary use

    3. Preservative and Fungicide Intermediate for Wood Protection Formulations

    Wood preservation chemical manufacturers use this compound as a core building block to create chlorinated phenolic fungicides. The product enters the formulation of industrial-grade wood preservatives where selective toxicity against mold and decay is required. The subject material is involved in synthesis pathways for compounds providing extended performance in outdoor timber, marine pilings, and railway tie preservation. The integration focuses on ensuring penetration depth and leach-resistance for treated wood, with quality benchmarks set by stringent environmental protocols.

    Industry compliance standards

    • AWPA (American Wood Protection Association) P9, P11: Standards for Wood Preservatives
    • US EPA 40 CFR Part 152: Pesticide Registration
    • EN 599-1: European Efficacy Requirements for Preventive Wood Preservatives
    • ISO 9001:2015 Quality Management Systems for chemical processing

    Typical usage ratio

    • Typically 10–30% in composite preservative concentrate; exact percentage calibrated to meet specific decay-resistance targets, timber cross-section size, and regionally allowed application levels.

    Downstream process integration

    • Converted into formulated emulsions, concentrates, or water-dispersible granules by reaction with auxiliary agents and carriers; subsequently applied to timber through vacuum-pressure impregnation or dipping processes.

    Final product types

    • Industrial treated lumber for construction
    • Marine-grade pilings and railway sleepers with anti-fungal treatment

    4. Precursor for Chemical Synthesis of Specialty Polymers (Epoxy Curing Agents)

    Chemical manufacturers employ this material to generate exclusively substituted phenols used as reactive components in the synthesis of epoxy curing agents. Its ability to confer thermal and chemical resistance enables the design of advanced resins for flooring, adhesive, and protective coating applications. Reactivity, purity, and chlorination profile are verified by in-process control to guarantee downstream compatibility during curing and polymerization steps.

    Industry compliance standards

    • EN ISO 9001:2015 for QMS in chemical and polymer production
    • REACH Regulation (EC) No 1907/2006
    • US EPA TSCA Inventory for raw material approval
    • ASTM D1652—Standard Test Methods for Epoxy Content of Epoxy Resins (for downstream QC)

    Typical usage ratio

    • 5–20% for formulated epoxy curing agent systems; concentration optimized according to polymer backbone design, viscosity management, and desired crosslink density in the final cured system.

    Downstream process integration

    • Transformed via controlled functionalization (e.g., Mannich-type reactions or further substitution) before incorporation into polymer compounding and subsequent blending with base epoxies during resin formulation.

    Final product types

    • High-performance epoxy adhesives for industrial bonding
    • Protective floor coatings and chemical-resistant linings

    5. Dye and Pigment Intermediate for Chlorinated Azo Compounds

    Manufacturers in the high-performance pigment sector use this material to synthesize certain chlorinated azo dyes, particularly those used for plastics, textiles, and specialty coatings. The input plays a key role during azo-coupling reactions where structural substitution modulates color hue and fastness properties. Processing controls address volatility and safety, with final pigment dispersions tested for heavy metal compliance.

    Industry compliance standards

    • EN 71-3: Safety of Toys—Migration of certain elements (for pigments in children’s materials)
    • OEKO-TEX Standard 100: Product Class I–IV (textile pigments)
    • REACH SVHC and Annex XVII (Azo restriction requirements in the EU)
    • ISO 1248:2019—Pigments—Requirements and test methods

    Typical usage ratio

    • 1–8% based on total pigment mass; addition level adjusted according to targeted chroma, substrate compatibility, and end-use color depth requirements.

    Downstream process integration

    • Undergoes diazotization and subsequent azo coupling within controlled batch reactors, yielding pigment intermediates which are then filtered, washed, and finished as dispersible powders or pastes for plastics and inks.

    Final product types

    • Chlorinated azo pigments for plastics coloring
    • Specialty dye dispersions for fiber, film, and coating applications
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    Certification & Compliance
    More Introduction

    2,4,5-Trichlorophenol: Insights from the Production Floor

    Direct Perspective from Chemical Manufacturing

    Crafting 2,4,5-Trichlorophenol starts with careful handling of its raw materials. Our years of experience working with chlorinated phenolics let us dig deep into the challenges and intricacies that come along with high-purity production. In practice, not every batch turns out easy. Small changes in temperature or impurity levels can require adjustments from the operators on the line. We train our crew to spot potential deviations that may affect downstream uses, especially since consistency means everything for customers in pharmaceuticals, agrochemicals, and industrial processes.

    The product comes out as off-white to pale yellow crystal solids, distinctly sharp in odor, and often forms needle-shaped particles. We learned to balance particle size because customers in herbicide production trust our processed intermediate for reliable solubility and minimal residue. Every step—starting from the choice of solvents, the reaction time, right on through to vacuum filtration and drying—affects the final result. It’s not just about passing a specification on paper, but ensuring actual performance matches the expectations our customers build their businesses on.

    Why 2,4,5-Trichlorophenol Remains a Key Chemical Intermediate

    A good number of industries find 2,4,5-Trichlorophenol indispensable because of the chlorine atoms precisely placed at the 2, 4, and 5 positions on the phenol ring. For herbicides, this particular arrangement offers selective chemical reactivity crucial for further synthesis into more advanced compounds. Our quality control laboratory follows rigorous GC and HPLC screening protocols. These instruments help us catch trace impurities that could react unpredictably in later stages.

    On the production floor, things like batch temperature profile and reaction pH become the difference between meeting contract specs—or missing them entirely. A slight moisture increase in storage drums over a humid summer can cause clumping, and operators stay vigilant for these small but critical details. As a factory, we not only watch the chemistry inside the reactor but also the impact of weather conditions, raw material fluctuations, and downstream storage variables. We understand how downtime or a noncompliant lot can disrupt a customer’s manufacturing schedule, leading to extra costs or batch reworks.

    How Specifications Drive End-Use Performance

    Most customers look for 2,4,5-Trichlorophenol with purity above 99%. Achieving this means tight controls from input raw material selection all the way to final packaging. We never take for granted the role of analytical testing. Nitroaromatic impurities and trace metal residues each create real headaches in applications like pharmaceutical intermediates. Our plant relies on both real-time line sampling and final batch assays before any product leaves the warehouse.

    Certain applications, such as the production of specialty herbicides and anti-microbial agents, depend on the physical form as much as the chemical assay. Clumped or melted product may seem trivial, but as we’ve learned, it can cause metering issues, overdosing, or even safety incidents on automated feeding lines at our customer’s plants. That’s why we sweat the details: packaging material, drum sizes, even anti-caking agents for long-haul shipments to tropical regions.

    Comparing 2,4,5-Trichlorophenol with Related Chlorophenols

    Among the various chlorophenols, 2,4,5-Trichlorophenol’s molecular structure sets it apart. Colleagues working in downstream R&D have emphasized time and again that substituent position on the aromatic ring determines each compound’s suitability. For example, compared to 2,4,6-Trichlorophenol or pentachlorophenol, our product offers a more targeted reactivity. The placement of chlorine atoms gives distinct reactivity, solubility, and toxicity profiles.

    As a manufacturer, we don’t lump all trichlorophenol products together. Experience tells us that mixing up 2,4,5-Trichlorophenol with 2,4,6-Trichlorophenol often leads to failed syntheses or off-spec end products. Substitution impacts everything—from melting point and aqueous solubility, to the rate of hydrolysis and behavior with metal salts. Customers in the pesticide industry always confirm which product they’re getting because interchangeability is not possible without risking synthesis efficiency, yield, or even environmental compliance.

    Managing Safe Handling and Environmental Responsibility

    On the factory floor, everyone understands 2,4,5-Trichlorophenol’s chemical reactivity and toxicity. We don’t take shortcuts. Standard PPE, local exhaust, and closed-system equipment are a minimum. Many of us have seen what accidental exposures can do, so nobody cuts corners on safety drills or incident reporting. Waste effluent handling takes top priority, both for plant safety and for our environmental obligations. Years of managing waste treatment systems taught us to maintain strict separation between chlorinated process water and regular plant effluent, so that no contamination winds up in the municipal supply.

    Solvent recovery from the process helps keep environmental impact down. In the past, industry practices sometimes fell short—chromatographic monitoring revealed how even trace contamination could stack up over weeks or months. Engineers at our plant developed a routine for gas scrubbing and activated carbon capture, something we refine year by year. We’re straightforward about the traditional risks attached to producing halogenated aromatics, and learned that environmental protection takes just as much daily effort as chemical processing itself.

    Workplace Experience and Customer Demands

    The workers on our line often see beyond certificates or formal documentation. Many of us have handled the same type of product for decades, so we spot subtle visual or olfactory cues that signal a possible deviation in quality—even before the QC lab results come back. For our largest accounts—mainly specialty chemical formulators and plant protection companies—early warning on a quality issue can mean the difference between a smooth campaign and a pile-up of off-spec inventory.

    We field customer calls almost weekly about adjusting shipping drum size, anti-caking packaging, or shipping temperature controls, especially during hotter months. Clients with big batch processes appreciate up-front notification of any changes, and we understand how sudden supply chain interruptions can create cascading problems beyond our factory gates. Years working in the plant help us appreciate these realities and foster habits of transparent, proactive communication.

    Common Challenges and Practical Solutions

    Chlorophenol production doesn’t leave much margin for error. Many issues stem from variable impurity profiles in incoming phenol or sodium hypochlorite. Unchecked impurities can cause secondary reactions, affecting both yield and purity. Throughout each year, our technical team works directly with suppliers to test and qualify each raw material shipment. In our experience, separating suspect lots at the factory door saves days of troubleshooting down the line.

    Temperature and humidity in our region fluctuate a lot between seasons. This often leads to minor clumping during storage, even with sealed packaging. Our solution—continuous monitoring of ambient conditions in our warehouse and swift corrective action—helps us maintain high consistency. For global shipments, we coordinate with logistics teams to reduce exposure during long stretches at customs or on docks.

    In certain batches, we’ve seen a slight yellowing or an off-smell that indicates low-level impurities. Teams have developed quick, in-house testing routines—so production managers can halt questionable lots, investigate in real time, and prevent waste or customer rejection. Experience gave us the confidence to empower anyone on the production floor with the authority to call a pause, without waiting for top-down instructions.

    Regulatory Expectations and Industry Shifts

    Recent years brought stricter international regulations governing chlorinated compounds. Our compliance department works closely with production, not just checking boxes, but incorporating standards into production methods. Regulations from Europe and North America push us to drive residual contaminants far below former industry limits. We invested in more precise analytical equipment and stepped up solvent recovery, aiming to get ahead of the tightening standards.

    Shipper and end-user expectations now routinely include detailed traceability documentation and strict shipment labelling. Years ago, traceability mostly mattered for customer audits, but now, batch documentation and chain-of-custody records answer custom inspections on both import and export shipments, and prepare us for surprise regulatory audits. We treat these requirements seriously because skipping a step can mean seized shipments and lost business. Our staff maintains careful batch recording, lot segregation, and digital archiving.

    How 2,4,5-Trichlorophenol Fits into Global Markets

    The market for 2,4,5-Trichlorophenol has its cycles, reflecting shifts in agrochemical demand, regulatory changes, and plant expansion projects. Our experience lets us plan around these swings, adjusting batch frequency and raw materials procurement. Team members pay close attention to supply forecasts from both herbicide and specialty chemical manufacturers.

    The trend toward greener chemistry puts direct pressure on all chlorinated product manufacturers. Bottlenecks in chlor-alkali supply or in global shipping lines make flexibility important. In past years, we faced delays that called for quick formulation changes or temporary capacity increases. In these times, our willingness to run overtime shifts or retool packaging lines provided much-needed relief to key clients.

    Supporting Industry Innovation and Collaboration

    Smaller customers and new entrants often reach out for technical advice on integrating 2,4,5-Trichlorophenol into new formulations. Some want pilot batch quantities for evaluating new pesticide actives or specialty resins. Our experienced staff fields questions about solubility in various organic solvents, compounding with auxiliary agents, and adapts sample packaging for research projects. Many of us know from hands-on work which approaches shorten trial-and-error learning curves for starters in specialty chemicals.

    Collaborative projects also emerge from interactions with academic groups and institutional labs. We provide small or specialty batch variants suited to specific research applications, sometimes adjusting the physical form or purity to suit custom testing regimes. That hands-on responsiveness comes from a culture of direct problem solving—not from standard protocols alone.

    Addressing the Differences That Matter to Customers

    Customers across sectors rely on our ability to distinguish 2,4,5-Trichlorophenol from other halogenated phenols—on chemical, analytic, and packaging levels. Failure to make those distinctions costs real money. From our side, there’s no room for mistaken delivery or ambiguous product labeling; preparation for each outgoing shipment verifies the requested model, and internal double checks cut error rates above what automated processes alone can provide.

    Physical attributes such as melting point and particle structure carry practical significance. Our plant controls drying cycles and crystallization rates to maintain a narrow range of crystal habits, letting our customers avoid issues such as screen blockages or inconsistent dissolution in their own processes. Colleagues at customer plants praise shipments with tight color and granularity ranges—they’ve learned the hard way that minor deviations make a big difference.

    Final Reflection from the Manufacturing Team

    Producing 2,4,5-Trichlorophenol is as much about attention to process details as it is about chemical know-how. Each specification—be it assay, moisture, impurity profile, or physical consistency—reflects actual experience with the way these factors impact customers’ critical applications. Problems that look small on paper become big in real world settings: excessive fines in a drum, a slightly off-color batch, or minor delays in shipment.

    Our approach stems from listening to colleagues, learning from the production floor, and acting on field feedback rather than relying solely on technical manuals. Over the years, we’ve seen how consistently applying those lessons helps customers trust our brand, reduce their own costs, and streamline their operations. Direct practical experience informs every decision, and we keep striving to improve with every new batch. By holding true to this, we support the industries that rely on 2,4,5-Trichlorophenol today, and help shape the advances that will come tomorrow.