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2,3-Xylenol

    • Product Name 2,3-Xylenol
    • Alias 2,3-Dimethylphenol
    • Einecs 202-453-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    686792

    CAS_number 526-75-0
    IUPAC_name 2,3-dimethylphenol
    Molecular_formula C8H10O
    Molar_mass 122.16 g/mol
    Appearance Colorless to pale yellow liquid
    Melting_point −2 °C
    Boiling_point 210 °C
    Density 1.02 g/cm³
    Solubility_in_water Slightly soluble
    Flash_point 87 °C
    Odor Phenolic
    Vapor_pressure 0.25 mmHg (25 °C)
    Refractive_index 1.529 (20 °C)

    As an accredited 2,3-Xylenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 2,3-Xylenol is packaged in a 500 mL amber glass bottle with a secure screw cap and chemical hazard labeling.
    Shipping 2,3-Xylenol should be shipped as a hazardous chemical in compliance with local, national, and international regulations. It must be packed in tightly sealed, chemically-resistant containers, labeled appropriately, and protected from heat, sparks, and open flames. Ensure proper documentation accompanies the shipment and only qualified personnel handle transport and storage.
    Storage 2,3-Xylenol should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers and acids. Protect from moisture and direct sunlight. Use safety cabinets designed for flammable liquids. Ensure proper labeling and keep away from heat or open flames to prevent fire hazards.
    Application of 2,3-Xylenol

    Applications of 2,3-Xylenol in Industrial Manufacturing

    As a direct manufacturer of 2,3-xylenol, we supply high-purity material tailored for advanced synthesis, performance modification, and specialty production processes. Below, we detail verified downstream industrial application segments and usage models, providing practical insight for procurement and R&D professionals.

    1. Synthesis of Antioxidant Intermediates for Lubricants

    Chemical manufacturers select 2,3-xylenol as a key methylphenol component for producing alkylated diphenylamines and hindered phenol antioxidants. These compounds improve oxidative stability in high-end lubricants and greases for automotive and industrial use. Through controlled alkylation, companies achieve specific molecular weights and steric profiles, required for long drain interval lubricants. Material integration occurs in dedicated synthesis reactors with real-time monitoring for impurity profile control and batch traceability.

    Industry compliance standards

    • ASTM D4951: Additive content determination in lubricating oils
    • SAE J183: Engine oil performance classification
    • REACH Regulation (EC) No 1907/2006: Substances registration and chemical safety
    • ISO 21461: Lubricant additives — Phenolic antioxidants analytics

    Typical usage ratio

    • 10–25% by mass of phenolic feedstock for target antioxidant synthesis
    • Ratio adjusted by molecular design for volatility resistance and solubility in finished lube base

    Downstream process integration

    • Direct feed into alkylation or condensation reactors as the phenolic source
    • Process steps include catalytic alkylation, neutralization, solvent extraction, and vacuum distillation
    • Batch or continuous flow reactors depending on capacity and process control requirements

    Final product types

    • Diphenylamine-based lubricant antioxidants
    • Phenolic antioxidant packages for synthetic and mineral oils
    • Grease additive concentrates

    2. Manufacture of Industrial Biocides and Fungicides

    2,3-xylenol serves as an essential phenolic precursor for the synthesis of cresol-based biocide actives. Agrochemical and specialty chemical makers employ specific methylation and halogenation chemistries to develop active ingredients for sanitizers, wood preservatives, coatings fungistats, and slime control in paper mills. Reliable purity and controlled trace element content from our production ensure consistency in formulation and regulatory acceptance.

    Industry compliance standards

    • BPR (EU) No 528/2012: Biocidal Products Regulation
    • 40 CFR Part 180 (EPA): Tolerance exemptions for pesticides
    • WHO/FAO: Specifications and evaluations for plant protection products

    Typical usage ratio

    • 30–60% by weight in phenol source blend for active intermediate synthesis
    • Adjustment based on halogenation degree and target spectrum of activity

    Downstream process integration

    • Initial charge in reaction vessels for methylation, halogenation or etherification
    • Followed by quenching and purification for downstream formulating
    • Quality checked for residual mono- and dimethylphenols

    Final product types

    • Cresol-based biocidal actives
    • Disinfectant concentrate formulations
    • Anti-fungal wood and paint additives

    3. Advanced Polymer and Resin Modifier Synthesis

    Producers of specialty resins and thermosetting polymers utilize 2,3-xylenol as a core precursor for tuning crosslinking density and thermal/UV resistance. Integration focuses on phenolic resin synthesis for high-performance electronic laminates, as well as in modified epoxy and novolac resins used in electrical insulation, circuit boards, and adhesives. Controlled addition into reaction step ensures compatibility, lowers free formaldehyde, and imparts extended service life in demanding thermal environments.

    Industry compliance standards

    • UL 94: Standard for safety of flammability in plastics
    • IPC-4101: Base materials for printed circuit boards
    • RoHS Directive 2011/65/EU: Restriction of hazardous substances
    • IEC 61249-2-7: Epoxy resin woven glass base for electronic assemblies

    Typical usage ratio

    • 5–20% by weight in phenolic content of resin formulations
    • Higher percentages for specific electrical or dimensional stability targets

    Downstream process integration

    • Introduced during resin pre-polymerization along with formaldehyde
    • Function: Modifies crosslinker structure; enables precise tuning of Tg and mechanical properties
    • Batch reaction and continuous resin finishing equipment

    Final product types

    • High-modulus phenolic resins for PCBs and FR-4 prepregs
    • Thermosetting electrical potting compounds
    • Resin systems for industrial adhesives and heat-resistant composites

    4. Synthesis of API Intermediates for Pharmaceutical Manufacturing

    Leading pharmaceutical companies engage 2,3-xylenol as an initial phenolic intermediate in multi-step synthesis of certain active pharmaceutical ingredient (API) building blocks, including aryl ether and substituted aniline derivatives. Strict batch documentation and controlled residual solvent levels from our production align with international quality metrics for regulated pharma applications. Integration can involve nitration, halogenation, followed by cross-coupling chemistry while maintaining product identity and impurity profiles within pharmacopoeial limits.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP-NF and EP monographs for intermediates
    • 21 CFR Part 210/211: FDA current GMP
    • ICH Q3A/B: Impurities in new drug substances

    Typical usage ratio

    • As low as 1–10 molar equivalents in API intermediate reaction pathways
    • Precise calculation based on stoichiometry of stepwise synthesis procedure

    Downstream process integration

    • Initiating agent or coupling partner in multistep organics lab-scale and pilot plant synthesis
    • Handles via closed system reactors with QC sampling and full traceability
    • Identifiable in impurity profiles of downstream API batches

    Final product types

    • Benzoxazole, benzanilide, and diaryl ether intermediates
    • API precursors for analgesic and anti-inflammatory drugs
    • Building blocks for antipyretic and antimicrobial agents

    5. Precursors for Dyes and Pigment Synthesis

    Specialty dye and pigment manufacturers employ 2,3-xylenol for diazotization and azo coupling reactions, leading to tailored colorants for plastics, printing inks, and textile applications. The ortho dimethyl configuration supports selective coupling and improved color fastness. Consistent isomer purity and minimized trace metals from direct manufacturing strengthen downstream color reproducibility and compliance with heavy metal restrictions.

    Industry compliance standards

    • EN 71-3: Safety of toys — migration of certain elements
    • Oeko-Tex Standard 100: Harmful substances in textiles
    • GHS/CLP Regulation (EC) No 1272/2008: Classification, labeling, packaging of dyes
    • REACH Annex XVII: Restricted substances in pigments and dyes

    Typical usage ratio

    • 5–20% by mass as phenolic compound feeding into azo synthesis reactions
    • Varies with intended dye shade and pigment load

    Downstream process integration

    • Acts as the starting phenol in diazotization and azo coupling reactors
    • Undergoes subsequent sulfonation and/or metallization for color modulation
    • Integrated online analysis to control shade and residual ortho-methylphenol

    Final product types

    • Azo dyes for plastics and polymers
    • Metal complex pigments used in automotive and industrial coatings
    • Dispersed dyes for polyesters and synthetic fibers

    6. Specialty Chemical Synthesis for Flavour and Fragrance Compounds

    Producers of specialty aroma and flavor chemicals use 2,3-xylenol as a controlled building block for synthesizing complex phenolic ethers and vanillin analogues. The compound enters sites where high-purity phenol sources are essential to maintain batch-to-batch reproducibility and meet food contact and aroma safety standards. Advanced functionalization chemistries enable both industrial-scale and laboratory-scale production of odor-active or masking agents.

    Industry compliance standards

    • FCC (Food Chemicals Codex) requirements for aroma intermediates
    • EC Flavour Directive 1334/2008: Flavourings and certain food ingredients
    • IFRA Code of Practice for fragrance raw materials
    • ISO 9235: Aromatic natural and synthetic derivatives

    Typical usage ratio

    • 1–10% by weight for specialty aroma ether synthesis in bulk production
    • Tailored to reactivity and target note strength

    Downstream process integration

    • Chemical feed for etherification, methylation or aldehyde formation
    • Analytical control to verify trace contaminants for food or perfume use
    • Collected and purified for compounding into blends

    Final product types

    • Synthetic vanillin or guaiacol derivatives
    • Odorant enhancers for detergents and cosmetics
    • Flavoring agents for food and beverage industry
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    Competitive 2,3-Xylenol prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    2,3-Xylenol — Product Insights from the Chemists Who Make It

    Introduction to 2,3-Xylenol

    In our daily routines in the chemical plant, 2,3-xylenol represents more than just another output. Every shift, we see what goes into creating a reliable raw material, one that faces real-world pressure across various sectors. Known by its chemical name as 2,3-dimethylphenol, it stands out among the isomer series for its consistency and profile. Our team tracks everything from purity levels to physical handling, because the margin for error in specialty chemistry leaves little room for improvisation. Over the years, our hands-on experience has shown which process variables demand extra attention and how minor adjustments can impact the final makeup.

    Day in, day out, the facility pulls in toluene and streams reactants through carefully managed catalytic reactors. Temperatures and feed rates rarely swing far before our monitoring systems flag the shift. Our model for 2,3-xylenol refinement has matured through decades on the line, with best practices shaped by both lab data and field incidents. From the first blend batch to the final drum seal, we treat this isn’t just a chemical — in pharmaceutical syntheses, resins, agrochemical intermediates, and high-grade solvents, its role keeps evolving with industry needs.

    Quality, Consistency, and Purity — How We Manage 2,3-Xylenol Production

    Inside the plant, we see more than raw numbers on a spec sheet. The typical model specification for 2,3-xylenol stays above 99% purity, with water and impurity levels measured in much finer detail; minor fluctuations can affect downstream reactions and equipment. Our experience says lab samples never tell the whole story without frequent on-line checks and careful storage protocols. For high precision jobs—such as intermediate synthesis for active pharmaceutical ingredients—slight variations in ortho and para isomer content mean the difference between a product that makes the grade and one that’s rejected.

    In early days, inconsistencies crept in when left unchecked. Repetition and smart troubleshooting closed those gaps. Crystallization temperature, for instance, needs steady watch, since 2,3-xylenol’s melting point differs from its close cousins. Tracking batches and instituting rapid-response cleanups after process upsets proved vital. Factory engineers and plant chemists talk shop every week, calibrating both reactors and operator skills. No automated line fixes itself—every analytical report gets paired with a memory of what happened on the floor.

    Why Customers Specify 2,3-Xylenol for Their Work

    Direct feedback from formulators tells us that 2,3-xylenol outperforms other isomers in several key applications. Its methyl placement suits certain sulfonation pathways and makes it a preferred starting material where para-substitution doesn’t fit the bill. Resin producers and dye houses notice how 2,3-xylenol handles well at elevated temperatures but avoids excessive volatility; this reliability reduces rework and off-spec batches.

    A manufacturer’s perspective rarely matches a distributor’s. We see firsthand why specific end users ask for our variant, not just any isomer blend. They rely on defined boiling point, lack of halogenated byproducts, and the straightforward separation from closely related compounds, something our continuous improvement efforts reinforce every quarter. Customers working with polymers see color stability and less unwanted crosslinking than with 2,4-xylenol; pharma customers tie product safety to both the absence of certain trace residues and consistent solubility profiles.

    The Subtle Differences: Comparing 2,3-Xylenol With Other Xylenols

    Across the xylene-derived phenols, small changes in chemical structure drive different results in practical use. The meta-positioned methyl groups in 2,3-xylenol influence both reactivity and physical behavior. Unlike 2,4-xylenol, which the plant also manufactures, 2,3-xylenol reaches a higher degree of resistance to unwanted side-chain reactions, a trait that makes a difference in pigment synthesis and agricultural chemical extraction.

    From the manufacturing side, separating the isomers takes precise control. Overlapping boiling points complicate downstream purification, especially during multi-ton campaigns. The process keeps us busy reading GC traces and responding to shifts, since a small drift can cascade into off-grade splits that challenge plant scheduling and waste management. Not every operator sees the point until the reject drum arrives, but quality assurance teams review every anomaly and feed that knowledge into process tweaks.

    There’s no shortcut; fractional distillation, solvent extraction, and selective crystallization each demand constant checks and operator know-how. As output increases each year, we keep bringing in new analytical tools, yet on-the-floor observations—smell, viscosity, crystal appearance—still catch plenty the instruments miss.

    Lessons From the Factory Floor: Challenges and Solutions Over Time

    On any given day, 2,3-xylenol reacts a bit differently than its isomer neighbors. Staying ahead means investing in both technology and people. We run a four-step QC process: feedstock assessment, reactor monitoring, post-reaction analytics, and pre-shipment review. Out in the lab, minor impurities can hint at a shift in feedstock origin or catalyst life span, so every batch triggers both routine and random sampling.

    One lesson our oldest operators hand down concerns batch-to-batch consistency. Even after two decades, thermal cycling during distillation can warp results. Procedures changed as we correlated subtle pressure blips with later off-odors in drum storage. People learn quickly when a trend emerges—so we make open feedback at the operator level a rule, not a suggestion. Production meetings feature front-line stories about “what just doesn’t look right.” Plant managers encourage this, knowing that a costly recall starts with overlooking a small process slip.

    Plant safety links closely to product handling. Even minor leaks or spills cause cascading effects, both in lost product and days spent cleaning unit ops. Our fire safety drills draw from incidents with phenolic compounds. The practical take—all tasks work better with a routine built around not just documentation, but habit. Operators log minor events in real time, not hours later. Spills drop sharply under this approach, and fewer incidents lead to better uptime for downstream blending and loading.

    End Uses — Bridging the Factory With Downstream Industry

    2,3-xylenol rarely serves as a final product; most of it flows into other syntheses. Resin manufacturers value its role as a crosslinker in high-performance adhesives. Paint and coating chemists talk about pigment dispersion improvement and superior film-forming characteristics. The pharmaceutical sector depends on its unique substitution pattern for targeted reactions, such as in intermediate steps to create more complex molecules.

    We pay attention to these final uses through reverse engineering failure cases. Customer complaints come direct; few complaints ever trace back to shelf life when our storage recommendations get followed. Instead, solution behavior, purity shifts, or unwanted tint usually tie back to feedstock or handling at the users’ end. Regular communication with large customers—by video call or site visit—gives our technical team deeper insight than spec sheets alone. These partnerships guide us to adapt entire procedures, often leading us to segregate production for especially demanding jobs, such as regulated pharmaceutical intermediates.

    Our records show that upstream supply issues—like a regional toluene shortage—lead to difficult choices on batch scheduling and alternate feed management. We don’t always have perfect control, but we prioritize contracted commitments to keep downstream production on track. In lean periods, open dialogue with customers helps reset expectations before supplies tighten. Transparency here earns long-term trust, even if it comes at short-term cost.

    Environmental Commitment: Managing Waste, Emissions, and Resource Use

    Any plant moving thousands of liters of aromatic chemicals faces real environmental hurdles. 2,3-xylenol synthesis produces both intended and unintended byproducts, calling for tight discipline around emissions and waste. Our process integrates closed-loop recovery wherever possible—solvents cycle back, and still residues head to dedicated treatment. Over the past decade, we scaled up vapor recovery and optimized condensers to catch fugitive losses. Operating permits grow steadily stricter, so nobody waits for the next inspection to fix an old valve or replace a worn gasket.

    We also share our waste reduction numbers with the public—stack emissions, effluent loads, mass balance closure—real data rather than adjusted projections. Our most effective step involved switching to lower-odor solvents, which reduced complaints in neighboring communities and cut measured VOCs in stack testing. Some process byproducts prove too persistent for in-house treatment; in these cases, we work with certified incineration partners, tracking chain of custody every step. This level of documentation supports both compliance and public confidence.

    Resource efficiency gets constant attention—not only for cost but for stewardship. Water recycling, heat exchangers recovering process energy, and automation that narrows tolerances all pay off in leaner operation. Over the years, the team learned that any waste points left unaddressed become future costs, whether in regulatory fees or neighbor trust.

    Safety and Regulatory Discipline at Every Turn

    Nothing about large-scale chemical manufacture stays risk-free, but our long view is that habitual safety builds both product quality and plant morale. We maintain regular review cycles for operational hazards, with both management audit and worker self-reporting. Engineering controls—like sealed transfer lines and over-pressurization interlocks—started as regulatory mandates but now anchor our own best practices, evident every day we avoid unplanned downtime.

    We maintain close records for batch traceability, supporting both customer queries and regulatory obligations. The evolution of global standards—toxicological studies, occupational exposure limits, labeling requirements—constantly pushes our review cycles. Each year, inspectors bring new interpretations of old laws, and we adjust documentation to match. Emergency procedures run alongside routine training; from a line supervisor’s perspective, this hybrid approach keeps both new hires and veterans ready for a rare plant upset.

    Continuous Improvement: Why Every Batch Counts

    One thing the manufacturing environment teaches is that change never stops. Over twenty years, automation took over large swathes of monitoring and sample handling, but hands-on intervention remains vital. The plant rewards attention to the little signs—an unexpected drift in product color, or a fraction of a percent change in purity reading. Quick analysis and open reporting turned near-misses into future safeguards. This culture of adjusting fast, backed by data and operator vigilance, pushed our plant output closer to zero-waste and allowed us to target higher-value markets.

    Learning doesn’t stop with the technical team. Customer returns, supply shifts, and plant downtime spur reviews. We keep a running log of every deviation—both on paper and in digital so operators from every shift can reference recent challenges. Over time, documentation evolved from formality to tool, helping every crew member to spot patterns and suggest smarter ideas.

    The message that sticks among new hires: every drum off the line carries our reputation, not only in specs but in dependable supply and trustworthy support. Getting this right calls for both technical skill and a willingness to rethink old routines when data—and hard experience—say the path forward shifted.

    Looking Forward — Shaping the Future of 2,3-Xylenol Production

    The next generation of plant upgrades aims at making cleaner, safer, smarter 2,3-xylenol. Digital process controls now spot deviations earlier, reducing yield losses and off-grade splits. New catalyst blends increase throughput with lower byproduct loads. Outside the plant, industry expectations keep shifting, with some sectors asking for enhanced traceability and others focusing on sustainable certifications. We prepare with transparent practices and rigorous self-assessment—long before auditors step through the door.

    While the technical benchmarks improve, soft skills grow just as important. Success hinges on building and maintaining the trust of both our internal teams and external partners. Chemical manufacturers shape the industrial backbone—a fact clear to every operator who spends their career getting each kilo of product right. The lessons we learned from years on the floor inform how we design, refine, and deliver every shipment of 2,3-xylenol to the world outside our gates.

    Far from just supplying a commodity, we see every batch as a commitment made real. From how we respond to a process upset, to the ways we work with downstream users on special requirements, the culture in the facility ensures the product we send performs in the field. We welcome new challenges—whether they come from emerging applications, tighter regulations, or global supply shifts—and the decades of experience behind our team means every solution is built on more than manuals and data points.