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2,3-Dichloroaniline

    • Product Name 2,3-Dichloroaniline
    • Alias 2,3-Dichlorobenzenamine
    • Einecs 220-527-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    213945

    Cas Number 608-27-5
    Molecular Formula C6H5Cl2N
    Molecular Weight 162.02 g/mol
    Appearance Light brown to beige solid
    Melting Point 45-49°C
    Boiling Point 245°C
    Density 1.36 g/cm³
    Solubility In Water Slightly soluble
    Flash Point 120°C
    Purity Typically ≥98%
    Synonyms 2,3-Dichlorobenzenamine
    Refractive Index 1.634
    Vapor Pressure 0.025 mmHg at 25°C

    As an accredited 2,3-Dichloroaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle labeled "2,3-Dichloroaniline, 99%, 100 g." Features hazard symbols, product details, and manufacturer information.
    Shipping **Shipping Description for 2,3-Dichloroaniline:** 2,3-Dichloroaniline should be shipped as a hazardous chemical according to regulations. It must be packed in tightly sealed, labeled containers, protected from physical damage and moisture. Transportation should follow UN 2209 guidelines, including required hazard labels. Avoid contact with incompatible materials and handle with appropriate personal protective equipment.
    Storage 2,3-Dichloroaniline should be stored in a tightly closed container, in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizers and acids. Protect from moisture, heat, and direct sunlight. Store in a designated chemical storage area, with clear labeling and secondary containment to prevent leaks. Always follow appropriate safety guidelines for toxic and hazardous substances.
    Application of 2,3-Dichloroaniline

    Applications of 2,3-Dichloroaniline in Industrial Manufacturing

    As the original manufacturer of 2,3-dichloroaniline, we focus on consistently supplying reliable raw material for complex downstream synthesis in specialty chemical industries. This section details the main application sectors, with a focus on core downstream formulations, process stages, and end product classes. Each segment reflects these applications as established by major industrial users, providing essential details for manufacturers integrating this material into production systems.

    1. Agrochemical Intermediate for Herbicide Synthesis

    Major herbicide manufacturers in the agrochemical industry rely on 2,3-dichloroaniline for the synthesis of selective and non-selective herbicidal compounds, including acetanilide and substituted aniline-based actives. The raw material enters multi-step synthesis where precise stoichiometry influences active concentration and field persistence. Compliance with residue and impurity standards is mandatory due to agricultural and food safety regulation. End products include herbicides registered globally.

    Industry compliance standards

    • FAO/WHO specifications for pesticide technical materials
    • EU Regulation (EC) No 1107/2009 (plant protection product approval)
    • US EPA 40 CFR Part 180 (tolerances for pesticide residues)
    • Good Laboratory Practice (GLP) and ISO 9001 for traceability

    Typical usage ratio

    • 0.2 – 0.6 molar equivalent per batch; adjusted based on target molecule and yield optimization

    Downstream process integration

    • Added during initial amination or condensation stages to form substituted aniline intermediates, followed by cyclization, alkylation, or acylation according to specific herbicide synthesis route

    Final product types

    • Technical grade herbicides (e.g., propanil, butachlor intermediates)
    • Formulated crop protection products (EC, SC, WG formulations)
    • Pre-tilled and post-emergence weed control actives
    • Active substance concentrates for regional product registration

    2. Dye and Pigment Manufacturing Intermediate

    Producers of high-performance dyes and pigments utilize 2,3-dichloroaniline for the creation of azo and anthraquinone derivatives, valued for lightfastness and specific color shades within textile, leather, and plastics manufacturing. Its unique dichlorination pattern enables coupling reactions, securing batch-to-batch reproducibility and chromatic consistency as required by international textile colorfastness and eco-certifications.

    Industry compliance standards

    • OEKO-TEX Standard 100 (textile dye safety)
    • REACH Annex XVII (substances of very high concern restrictions)
    • ZDHC Manufacturing Restricted Substances List (MRSL) for dyes
    • ISO 105 series (color fastness in textiles)

    Typical usage ratio

    • 4–15% by dry weight, depending on chromophore target and color depth sought

    Downstream process integration

    • Charges as a diazo component or substituted aniline precursor in coupling reactions, followed by purification, crystallization, and granulation for pigment formulation

    Final product types

    • Disperse and acid dyes for synthetic and animal fibers
    • Pigments for masterbatch plastics and coatings
    • Colorants for inkjet, aqueous inks, and automotive finishes
    • Process dyes for leathers and technical textiles

    3. Pharmaceutical Intermediate for Active Pharmaceutical Ingredient (API) Synthesis

    GMP-compliant pharmaceutical manufacturers incorporate 2,3-dichloroaniline as a critical intermediate in synthesizing specific APIs, notably in the anti-infective and antipyretic categories. Its controlled use is essential to meet pharmacopeial purity thresholds and manage residual solvent limits, while traceability is ensured via validated batch production records and qualification audits.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for APIs
    • European Pharmacopoeia (Ph. Eur., relevant monographs for APIs)
    • US Pharmacopeia (USP)
    • Chinese Pharmacopoeia (ChP) and DMF registration for regulated markets

    Typical usage ratio

    • 1.0–1.2 molar equivalent in key condensation or substitution steps per batch, with close monitoring for intermediate purity

    Downstream process integration

    • Input into initial N-chloroaniline syntheses, followed by further functional group modifications (e.g., amide formation, halogenation), prior to final API purification, crystallization, and milling

    Final product types

    • API intermediates for antipyretics such as acetophenetidin derivatives
    • Active pharmaceutical ingredients with dichloroaniline fragments
    • Bulk drug substances for oral or topical finished dosage forms
    • Contract-manufactured intermediates for regulated markets

    4. Synthesis of Specialty Organic Chemicals for Polymer Additive Manufacturing

    Manufacturers of specialty polymer additives and functional materials implement 2,3-dichloroaniline as a foundational block for heat stabilizers, UV absorbers, and chain terminators in engineered plastics. Its dichlorinated aromatic structure confers thermal stability and compatibility for polymer blends, maintaining compliance with plastics industry additive restrictions and RoHS regulations.

    Industry compliance standards

    • EU RoHS Directive 2011/65/EU and amendments (hazardous substances in electronics)
    • FDA 21 CFR 177 (additives for polymer contact with food)
    • ISO 1043-5 (polymer additives classification)
    • UL 94 (fire safety for polymers, where additive performance is validated)

    Typical usage ratio

    • 0.1–2.5% by weight in additive blending; dosing based on target property improvement, regulated limits, and final application environment

    Downstream process integration

    • Incorporated in synthesis of additive masterbatches via melt compounding or solvent blending, prior to extrusion, molding, or film blowing operations for end-use plastics

    Final product types

    • Polymer stabilizers for polyolefins, ABS, PVC
    • UV-absorbing masterbatches for outdoor films and packaging
    • Heat-resistant additives for automotive and electrical housing
    • Chain regulators for high-performance engineering plastics

    5. Intermediate for Agricultural Fungicide Production

    Leading fungicide producers utilize 2,3-dichloroaniline to build substituted anilinic structures central to modern protective agents used on high-value fruit, vegetable, and cereal crops. Its selection affects both final compound bioactivity and environmental safety, with production governed by international agricultural chemical standards and end-use registration dossiers.

    Industry compliance standards

    • Codex Alimentarius MRL standards (pesticide residues)
    • ISO 23101 (requirements for pesticides in agricultural use)
    • China GB 2763 (National Food Safety Standard - pesticide MRLs)
    • Global GAP, SQF, and HACCP where fungicide use impacts food production chains

    Typical usage ratio

    • 0.18–0.45 mol/mol relative to the specific core reactant; optimized per fungicide molecular structure

    Downstream process integration

    • Introduced in substitution and cyclization steps for synthetic triazole, dicarboximide, or strobilurin fungicide frameworks, followed by crystallization and formulation into market-ready products

    Final product types

    • Active fungicidal ingredients for field and postharvest protection
    • Suspension concentrate (SC) and water-dispersible granule (WG) formulations
    • Ready-to-use crop protection solutions for export markets
    • Bulk actives for contract formulation and regional compliance testing
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    Certification & Compliance
    More Introduction

    Understanding 2,3-Dichloroaniline: Manufacturer Insights on its Value and Applications

    Direct Knowledge from the Factory Floor

    Every year, our production teams work with a wide range of chlorinated aniline derivatives, but there’s a distinct interest surrounding 2,3-Dichloroaniline. It’s a versatile, pale yellow crystalline compound with the molecular formula C6H5Cl2N, and through steady process innovations, we keep refining its synthesis. Years of hands-on experience with its manufacturing and quality control have taught us how tightly regulated production maintains a clean profile, minimizing unwanted isomers and impurities that would otherwise trouble our customers downstream.

    In the plant, synthesis starts with careful selection of chlorinated precursors. The reactions need a stable, controlled environment, not just to achieve a high yield, but to avoid generating too much 3,4- or 2,4-dichloroaniline, which can complicate purification. Over time, investments in precise instrumentation and batch analytics have reduced the risk of these byproducts, ensuring 2,3-Dichloroaniline comes off the line with reliable purity. What matters most here is predictability: chemists and engineers don’t want surprises, and neither do end users.

    Batch Properties and Key Specifications

    Across each lot, we target purity levels above 99%, because trace contamination in intermediates tends to escalate problems as molecules move downstream, especially in pharmaceuticals or dye manufacture. Standard crystalline material comes with a melting point between 52°C and 54°C, meeting the tight reproducibility standards we demand in quality audits. Through years of refinement, trace moisture and low boiling residuals are tightly monitored—not just because specifications require it, but because these details shape final product consistency in customer applications.

    Particle size control makes a real difference, especially where dissolution performance or filtration speed matters. Our crystals are never left coarse or dust-like; grinding and sieving happens in lines with continuous monitoring. Dust can create problems in blending and can even raise safety questions during handling, so smoothing this part of the process took time, trial, and patience. Packaging standards changed over the years as well. Now, 2,3-Dichloroaniline leaves our facility in tightly sealed drums with anti-static liners, preventing ambient moisture pickup or charge accumulation during transport.

    How 2,3-Dichloroaniline Fuels Innovation

    From experience, the greatest demand comes from textile dye and pigment synthesis. The chemical cores of some of the most colorfast azo and anthraquinone dyes use 2,3-Dichloroaniline as a starting amine. Success stories in the field hinge on consistent input material; even minor changes in substitution patterns can show up as faded shades or reduced fastness on fabric. Our technical team spends a lot of time with manufacturers on-site, working to align process parameters and solve issues tied back to raw material quality.

    The compound pulls its weight as an intermediate in agricultural chemicals, too. Herbicides and fungicides with complex substitution require high-fidelity building blocks. Here, small impurities can disrupt catalytic reactions, so we take feedback from agrochemical developers seriously. Adjustments on our end—whether it’s to reduce trace isomers or tweak packaging to shield from light—came directly from conversations with downstream R&D teams. The lesson is straightforward: chemistry developed in the lab needs tight coordination with manufacturers to scale successfully.

    Some pharmaceutical syntheses also call out for 2,3-Dichloroaniline’s unique reactivity—whether in anti-infectives or as a scaffold for more complex molecules. The pharmaceutical industry’s strict regulations shape how we operate: batch traceability, archive retention, and supply chain visibility matter. Our experience has shown that pre-audit dialogue with customer QA makes these projects smoother on both sides, letting us adapt aspects of the process before any regulatory bottleneck appears.

    Compared with Other Dichloroanilines

    Working directly with both 2,3- and 2,4- isomers shows that small shifts in the position of chlorine atoms translate into major practical changes. 2,4-Dichloroaniline, for instance, finds its main role in manufacturing the herbicide 2,4-D. Its melting point and solubility differ from the 2,3- isomer, which means handling methods in our plant and in customer facilities can’t be one-size-fits-all. 3,4-Dichloroaniline, by contrast, can have more pronounced toxicity and doesn’t deliver the same balance of reactivity or downstream safety as the 2,3- version.

    Many buyers assume interchangeability if they’re new to these compounds, but practical experience in synthesis shows why each isomer gets its own dedicated production and storage lines. Small cross-contaminations between isomers in bulk lots set back entire projects, so we don’t cut corners in changeover or cleaning. Teaching new technical staff the differences takes time, but after a few mistakes in early days, fail-safes became second nature. Lessons from these learning curves helped tighten our process documentation, and today, line batch records track every step, every lot.

    Environmental and Safety Considerations

    Handling chlorinated anilines calls for respect and tight operational discipline. We saw early on that even short-term exposures to vapors—especially during drying or milling—demanded improved containment and air monitoring. Over several years, we upgraded HVAC and deployed better personal protective equipment, reducing both accident rates and employee turnover. These investments never seemed like a luxury. Keeping our workforce healthy not only builds trust, but also sustains the knowledge that decades on the floor bring.

    Waste treatment requires just as much attention. Our facility runs closed-loop solvent recovery units, slashing both disposal needs and environmental impact. The solid process residues that don’t fit our re-use routines get classified and directed toward licensed hazardous waste handlers. Adopting tougher in-plant controls followed increased scrutiny worldwide, and regulatory changes taught us to get ahead of the curve, not just match the letter of the law. If customers ask for documentation on effluent quality or zero-discharge practices, we have years of records to share.

    Sustaining Quality in a Volatile Market

    Markets for bulk organic intermediates like 2,3-Dichloroaniline don’t stand still. Shortages of chlorine or upstream feedstocks, shifting environmental controls, and major weather-related disruptions have all hit the industry over the years. We learned to insulate inventories by investing in storage and local sourcing, not just to maintain reliability, but also to keep pricing less exposed to swings on the global market. Stable relationships with raw material suppliers let us scale up or adjust scheduling ahead of uncertainties, and our customers see that in consistent lead times.

    Technical support isn’t just an add-on; it's central to how we work with customers big and small. Teams often call us in the midst of troubleshooting batch failures or adjusting downstream syntheses. Real-world process hiccups—like unexpected color drift in pigments or trace byproduct formation in fine chemicals—often get traced back to input quality. Open lines of communication mean these problems rarely linger once they’re exposed, and we value the trust built when companies know they’re dealing with the actual manufacturer, not an anonymous trader. Over time, small technical discussions, site visits, and audit support become the foundation for long-term alliances.

    The Role of Continuous Improvement

    Consistent investments in R&D allow our team to tweak manufacturing steps and raise both yield and quality benchmarks. Several years back, process engineers overhauled the catalyst systems for the chlorination stage, reducing energy usage and cutting particular impurity peaks that were harder to separate later. Even small energy savings or yield increases compound over hundreds of metric tons produced. Continuous improvement projects don’t just exist in management slogans; they’ve shaped how we compete and how new chemists build practical know-how on the plant floor. Ideas that show up in customer complaints or lab discovery cycles often become the backbone of future process upgrades.

    Supply chain transparency has become a frequent theme in conversations, especially as multinational buyers want to map out every node in their sourcing. Full traceability came through investments in ERP systems and batch tracking software, but a lot of the work still means someone in the plant digging through records or, sometimes, asking an older operator about a line issue from years ago. We keep those stories alive—lessons from a compressor failure or moisture incident—because customers benefit from a culture that prizes shared experience over just ticking compliance boxes.

    Challenges Unique to 2,3-Dichloroaniline

    Some organic products never stop challenging those who manufacture them, and 2,3-Dichloroaniline is no exception. Achieving high purity demands constant vigilance against process drift, equipment residue, or contaminants drawn in by atmospheric shifts between seasons. Unlike more forgiving chemicals, even slight mishandling during crystallization leads to color changes or loss of flow, setting back entire production runs. Our lab team learned to adapt solvent ratios and crystal growth conditions based on real-time seasonal data, not just fixed recipes from textbooks. Years of logging these parameters paid off, as small tweaks often spell the difference between wasted effort and a perfectly running lot.

    The value of 2,3-Dichloroaniline to our customers comes less from an abstract market profile and more from the direct downstream results they see. A pigment manufacturer doesn’t care for chemical trivia—they care that their finished dye binds tightly to fiber, lasts through repeated washing, and doesn’t leach trace contaminants that pose compliance hurdles. Agrochemical researchers ask pointed questions about reactivity or background noise in analytic tests: if a trace impurity crops up, their pilot batches can fail. Delivering product with that in mind makes honest dialogue and feedback loops from both sides a core part of our day-to-day quality operations.

    Reflections on Decades of Experience

    Stepping back after years of production, it’s clear that the story of 2,3-Dichloroaniline depends on knowledge exchanged between operators, chemists, customers, and sometimes even regulators. Years ago, process lines struggled with legacy equipment, leading to bottlenecks and inconsistent melt point readings. Those problems only got solved by blending field observations, structured process mapping, and—sometimes stubborn—experimentation by operators who saw where numbers didn’t line up with theory. Customers who worked with generic suppliers often reported missed delivery dates, unexplained specification drifts, or changing physical properties with each shipment. By emphasizing stability, predictability, and transparency, our facility built a reputation that outlasted those who cut corners for short-term gain. Contracts followed quality, not price alone, as buyers who needed their product to perform in high-stakes applications put their trust where long track records and responsiveness were proven facts.

    Looking Ahead: Meeting Tomorrow’s Standards

    Expectations for chemical manufacturing keep changing as regulatory, consumer, and technological forces evolve. Within our walls, green chemistry initiatives—using safer reagents, closed-loop operations, and energy recovery—are moving from corporate vision statements into everyday practice. 2,3-Dichloroaniline still demands careful material stewardship and robust supply lines, but every year, incremental advancements in process and policy mean lower emissions, safer workplaces, and tighter compliance records. Feedback from end-users fuels much of this progress. Customers testing new coatings, textiles, or compounds ask sharper questions and demand richer technical support. Teams work both in the lab and at production scale to backstop claims about purity, performance, and environmental impact. In a climate where brand reputation rides on the reliability of every molecule, open communication, rigorous documentation, and a proven manufacturing pedigree count more than ever.

    As a chemical manufacturer with decades of first-hand experience, we know that real value comes less from data sheets and more from the energy, skill, and institutional memory carried by our teams. The story of 2,3-Dichloroaniline is still being written with every batch we make, every customer issue we solve, and every process innovation we adopt. Focusing on real-world outcomes, we’re committed to keeping both our standards and our relationships strong—evolving alongside the industries and communities that depend on our work.