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2,3-Dichloro-1,4-Naphthoquinone

    • Product Name 2,3-Dichloro-1,4-Naphthoquinone
    • Alias DCNQ
    • Einecs 211-295-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    349958

    name 2,3-Dichloro-1,4-Naphthoquinone
    chemical_formula C10H4Cl2O2
    molecular_weight 227.05 g/mol
    CAS_number 82-48-6
    appearance Yellow crystalline powder
    melting_point 180-182°C
    solubility_in_water Insoluble
    solubility_in_organic_solvents Soluble in chloroform, ether, and benzene
    density 1.61 g/cm³
    purity Typically ≥98%
    storage_conditions Store in a cool, dry place, tightly closed

    As an accredited 2,3-Dichloro-1,4-Naphthoquinone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 25g amber glass bottle features a tight-sealed cap, clear hazard labeling, and displays "2,3-Dichloro-1,4-Naphthoquinone" prominently.
    Shipping 2,3-Dichloro-1,4-Naphthoquinone should be shipped in tightly sealed containers under cool, dry conditions. It is classified as a hazardous material and must be handled according to relevant chemical safety regulations. Ensure clear labeling, use secondary containment, and follow all shipping guidelines for oxidizing or environmentally hazardous substances.
    Storage 2,3-Dichloro-1,4-Naphthoquinone should be stored in a tightly sealed container, away from direct sunlight, heat, and moisture. Keep it in a cool, well-ventilated area, separate from incompatible substances such as strong oxidizing agents and bases. Ensure the storage area is clearly labeled and equipped for handling hazardous chemicals, following local regulations for chemical safety and containment.
    Application of 2,3-Dichloro-1,4-Naphthoquinone

    Applications of 2,3-Dichloro-1,4-Naphthoquinone in Industrial Manufacturing

    As a primary manufacturer of 2,3-Dichloro-1,4-Naphthoquinone, we supply this specialty intermediate to a range of advanced chemical industries requiring precision raw materials. Below are the leading downstream application sectors, with detailed compliance, formulation, integration, and end-use perspectives relevant for procurement, quality management, and technical production teams.

    1. Agrochemical Synthesis – Herbicide and Fungicide Intermediate

    Agrochemical firms utilize 2,3-Dichloro-1,4-Naphthoquinone as an essential building block in the synthesis of selective herbicides and fungicidal actives. Its dichlorinated naphthoquinone structure provides the core for halogenated crop protection molecules, supporting targeted field performance and resistance management profiles. Advanced synthesis routes incorporate this intermediate during key condensation and halogenation stages, with process operators controlling concentrations to optimize target molecule yield while meeting trace impurity guidance in regulated markets.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • ISO 9001:2015 Certified Quality Management Systems for Agrochemical Manufacturing
    • EU Regulation (EC) No 1107/2009 on Placing of Plant Protection Products
    • US EPA Pesticide Registration Requirements (40 CFR Part 158)

    Typical usage ratio

    • 3–8% w/w as a structural intermediate, depending on the downstream active ingredient formulation; technical teams adjust ratios according to desired halogenation degree and reaction kinetics

    Downstream process integration

    • Added during stagewise condensation or cyclization in multi-step synthesis for aryl-substituted herbicides or naphthoquinone-based fungicides
    • Feeds directly into C–C or C–O coupling reactions under controlled anhydrous conditions

    Final product types

    • Selective pre- and post-emergence herbicides for cereals, legumes, and specialty crops
    • Systemic and contact fungicides for fruit, vegetables, and industrial crops

    2. Dye and Pigment Manufacturing – Halogenated Quinone Coloring Agents

    Specialty dye and pigment plants incorporate this dichloro naphthoquinone compound as a critical intermediate to produce vivid, lightfast quinone-based colorants. The molecule’s electronic properties enable coupling with aromatic amines and phenols, yielding stable pigments for high-value applications. Operations incorporate the intermediate into both batch and continuous synthesis lines, with QC teams monitoring residuals and color strength in accordance with sector regulations for technical textiles and coatings.

    Industry compliance standards

    • OEKO-TEX® Standard 100
    • REACH Regulation (EC) No 1907/2006 for Substances of Very High Concern (SVHC)
    • ISO 9001:2015 for Dye and Pigment Production
    • GHS Labeling and Safety Standards (UN Globally Harmonized System)

    Typical usage ratio

    • 8–15% by mass within pigment synthesis stages or chromophore modifications; formulation chemists select input level based on color concentration and purity targets appropriate for final application

    Downstream process integration

    • Enters as a coupling or condensation reactant after pre-filtration and solvent adjustment in pigment synthesis
    • Facilitates formation of extended π-systems during aromatic amine/phenol coupling under mild acid or base catalysis

    Final product types

    • Naphthoquinone-based colorants for automotive coatings, inks, and plastics
    • Reactive and disperse dyes for textiles, fiber, and paper manufacturing

    3. Pharmaceutical Intermediate for API Synthesis – Antimicrobial and Antineoplastic Agents

    Pharmaceutical manufacturers leverage chlorinated naphthoquinone derivatives as building blocks in the synthesis pathway of certain antimicrobial and oncology drug substances. The intermediate’s chemical stability and electrophilic nature allow for regioselective introduction of functional groups that form the active cores of specialized APIs. GMP production sites employ validated purification and traceability protocols to comply with global regulatory frameworks while selecting precise loading levels to minimize side reactions.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • USP/NF and Ph. Eur. Monograph Guidelines (where applicable to intermediates)
    • 21 CFR Parts 210/211 (US FDA cGMP)
    • EU Directive 2001/83/EC for the Safety of Medicinal Products

    Typical usage ratio

    • 0.5–2.5 molar equivalents per downstream API, tuned according to catalytic efficiency and the specific synthetic sequence for the active substance

    Downstream process integration

    • Acts as the core halogenated scaffold during the early or middle synthesis stage, often as the acceptor in nucleophilic substitution or oxidative coupling with heterocycles
    • Subject to intermediate purification and inline QC release before further derivatization of the API

    Final product types

    • Semi-synthetic antimicrobial agents for dermatological and systemic use
    • Naphthoquinone-derived antineoplastic agents for targeted cancer therapies (investigational and approved)

    4. Specialty Polymer Additives – Crosslinking and Charge-Transfer Complex Formation

    Advanced polymer material producers adopt dichlorinated naphthoquinone compounds as functional additives to introduce crosslinkable sites or modify electronic characteristics in specialty plastics and resins. Its quinone structure interacts with electron-rich co-monomers, promoting efficient network formation and enhancing stability for use in technical films, ESD materials, and photoconductive layers. Process engineers integrate the additive during in situ polymerization or masterbatch compounding, guided by endpoint property requirements and batch consistency targets.

    Industry compliance standards

    • ISO 14001:2015 for Environmental Management in Polymer Manufacturing
    • RoHS Directive 2011/65/EU (for electronics-related plastics)
    • ISO 9001:2015 for Polymeric Additive Production
    • UL 94 Flammability Standards (if used in electronic or automotive applications)

    Typical usage ratio

    • 0.3–1.2% by total polymer mass, adjusted for degree of functionalization, desired crosslink density, and additive dispersion quality

    Downstream process integration

    • Added to monomer blends or pre-polymers before polymerization
    • Integrated via melt blending or solvent dispersion during compounding to assure even additive distribution in advanced functional materials

    Final product types

    • Antistatic films and coatings for electronic packaging
    • Photoconductive polymer sheets and microelectronic substrate laminates
    • Specialty engineering plastics with increased crosslinking and thermal stability

    5. Organic Synthesis – Catalyst Component in Fine Chemical Manufacturing

    Producers of complex fine chemicals utilize this dichloro quinone as a redox-active catalyst in selected organic reactions, such as oxidative coupling, halogen exchange, and electron transfer-mediated syntheses. The intermediate’s halogenation pattern enables fine-tuning of redox potential, providing highly selective catalytic performance in the formation of custom molecules for next-generation material, fragrance, and chemical reagent markets. Chemists weigh precise input based on substrate electron density and scale to optimize both conversion and downstream safety compliance.

    Industry compliance standards

    • ISO 17025:2017 Accredited Analytical Laboratories for Process Control
    • Responsible Care® Program Certification
    • National and regional workplace chemical safety regulations (OSHA, REACH, local equivalents)
    • Internal QC Protocols for Low-Trace Heavy Metal and Residual Solvent Limits

    Typical usage ratio

    • 0.8–3.0 mol% relative to limiting substrate; adjusted per kinetic rate, desired conversion efficiency, and required product purity

    Downstream process integration

    • Introduced with substrates at the reaction setup for catalytic oxidative coupling
    • Employed under controlled temperature and solvent conditions to maximize selectivity and minimize byproduct formation

    Final product types

    • Specialty fragrance molecules and aroma chemicals
    • Intermediates for functional advanced materials
    • Precision laboratory reagents for research and analytical markets
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    Certification & Compliance
    More Introduction

    2,3-Dichloro-1,4-Naphthoquinone: Direct Insights from the Manufacturing Floor

    Introduction: Working with 2,3-Dichloro-1,4-Naphthoquinone

    In our experience as chemical manufacturers, handling 2,3-Dichloro-1,4-Naphthoquinone isn’t just another day at the plant. This material commands respect on several levels—chemically, physically, and in its substantial usefulness across a spectrum of industrial processes. Our years in this business have shown us which naphthoquinone derivatives hold genuine value for manufacturers and researchers alike, and this compound stands out for good reasons rooted in reliable performance and chemical versatility.

    Physical Properties and Manufacturing Practice

    Every time we produce a batch of 2,3-Dichloro-1,4-Naphthoquinone, the process speaks to both challenge and reward. Achieving the required white to slightly yellow crystalline appearance signals the reaction has proceeded as it should. From a technical point of view, this compound features a molecular formula of C10H4Cl2O2 and a molecular weight just under 245 g/mol. Those numbers translate into a product that functions efficiently without unnecessary byproducts, which always helps with reproducibility. Purity typically exceeds 99%, and our analytical teams can verify melting points above 190°C—rounded off after decades of fine-tuning process controls and operational discipline.

    Impurities matter here. Low-level impurities can skew polymerization reactions or downstream syntheses significantly. Experienced operators at our production site monitor not only yields, but crystalline uniformity and byproduct removal, tackling solvent purification and even fine filtration with hands-on adjustments. We emphasize hands-on because naphthoquinones don’t always behave predictably; subtle changes in moisture, pH, or temperature during synthesis affect final properties, so only experienced manufacturing crews assure that each kilogram meets specification.

    What 2,3-Dichloro-1,4-Naphthoquinone Does Differently

    Among those working in organic synthesis or polymer chemistry, comparisons often surface between this compound and related naphthoquinones or other chlorinated quinones. After decades of customer feedback and long-term application studies, some differences become clear from our vantage point. While para-benzoquinones draw interest for milder reactions or lower toxicity, 2,3-Dichloro-1,4-Naphthoquinone positions itself in that sweet spot between strong reactivity and manageable handling properties. Two chlorine atoms at the 2 and 3 ring positions tweak the electron density significantly, making this quinone a more potent electrophile in certain substitutions or redox steps than its close relatives.

    Chemists reach for this material when they need something more assertive than plain naphthoquinone, but more predictable than higher chlorinated versions that can scorch reaction conditions or skew regioselectivity. Many polymer manufacturers experiment with dozens of aromatic diketones, and we see a clear preference for this compound because it threads the needle between solubility and reactivity. Getting solid, powder, or granular forms has helped synthetic chemists design scalable processes—whether for medium-scale batch reactors or pilot synthesis runs.

    Usages Rooted in Real Industrial Demands

    We see our product leave the factory floor for a wide set of applications, but certain end uses come up again and again—each with stories behind them. Synthetic chemists prize this quinone for introducing chlorine functionalities into molecules that have to withstand heat, oxidation, or photo-degradation. In practical terms, that means our compound finds its way into specialty dyes and pigments—where molecular stability translates into colorfastness. We ship material to companies building organic semiconductors, where chain uniformity and predictable redox properties allow them to tune electronic and optical performance in device components. Polymer science teams consume kilos for use in crosslinking steps, especially in fluoropolymers or elastomers.

    Pharmaceutical and agrochemical developers come to us with even more demanding needs. While the compound does not serve as an API, it supplies crucial building blocks—adding reactive chlorine atoms to ring systems that will bear much heavier molecular responsibilities downstream. Often, this single step saves countless hours and halves purification costs in research timelines. Our role involves not just shipping drums of material, but working out custom purity or particle size distributions, knowing that a minor change in micron size or water content determines whether an intermediate project hits its yield targets or gets scrapped.

    Having worked alongside research chemists at plant scale, we listen carefully to requests for small pilot lots or modifications, documenting not just lot numbers but batch stories. Is the customer concerned about trace solvent carryover? Are there downstream hydrogenation steps where a slightly less crystalline form could reduce clogging in filter beds? Maintaining an open technical dialogue, we meet these challenges by modifying reaction conditions, purification techniques, or packaging. Over time, best practices evolve directly from customer feedback and our own hands-on learning. These changes never come from a manual, but through dialogue, experimentation, and a straightforward commitment to improvement.

    Environmental and Handling Perspectives

    Managing a chlorine-bearing aromatic quinone means understanding the intersection of safety, environmental impact, and regulatory expectation—not just for finished goods but through every step, from raw materials to waste stream. Manufacturing at scale, we tackle environmental stewardship head-on. Chlorinated aromatics sometimes carry baggage from other industries, with legacy stories of mishandled waste and off-spec batches causing headaches for years. Our operation has invested in air abatement systems and solvent recovery towers that minimize emissions, backed up by third-party audits and operator training that focuses on spill prevention and worker protection.

    We work closely with our logistics teams to ship material in packaging optimized for stability and safety, from small glass containers for R&D teams up to fiber drums and lined metallic barrels for bulk users. Transport regulations change, but safety best practices don’t: correctly packed material, complete documentation, driver education, and open lines to customers matter just as much as chemical properties. We track each order right down to the truck or container, logging storage conditions and transit histories, so issues rarely arise. Where possible, reclaimed solvent gets returned to the front end of the process; solid byproducts are managed according to strict regulatory frameworks, protecting both our team and the greater community.

    On the production floor, workers draw on real-world experience for everything from emergency preparedness to routine storage. Naphthoquinones don’t tolerate moisture or prolonged UV exposure well, so we install redundant climate control, humidity monitors, and low-wattage lighting in storage and transfer points. Our best operators know these controls better than automated alarms—nothing replaces hands-on vigilance in chemical manufacturing.

    Real-World Challenges and Down-to-Earth Solutions

    Like any long-time manufacturer, we see challenges in keeping the production of 2,3-Dichloro-1,4-Naphthoquinone both efficient and sustainable. Sourcing high-quality precursor chlorinated compounds can take more work than textbooks suggest, especially with global fluctuations in raw material markets. Price swings for base naphthols and solvents often hit in cycles, but our purchasing team stays nimble, cultivating several supplier relationships and routinely qualifying new sources to ensure continuity. Scaling up from laboratory routes to commercial reactors exposes new bottlenecks around heat management, agitation, and purity—our production engineers have refined parameters over years of incremental improvements, tuning not only reaction times but also work-up and crystallization sequences.

    Factory downtime from maintenance or audits creates pressure to ship on schedule. Our plant personnel, many of whom have worked with us for decades, strike a balance between meeting customer deadlines and never sacrificing product integrity. Batch records point out whether an August shift coped with high humidity or if a late winter run needed extra drying time. These details feed directly into predictive models, but human insight and pride in quality put the final stamp on each outbound lot.

    Customer needs push us to adapt—not once, but continuously. Innovations in pigment or semiconductor chemistry prompt requests for finer particle grading or lower residual solvent. We expanded our micronizing and vacuum drying capabilities not in anticipation of a speculative order, but in direct response to recurring customer feedback. Each new specification, whether for an aerospace client wanting even tighter impurity limits or a university lab looking for small research samples, becomes a learning opportunity. Troubleshooting any issues—dissolution rates, batch-to-batch color variation, thermal stability—means more than comparing COAs, it means hands-on investigation. Only the combination of technical understanding, practical know-how, and humble listening powers those improvements.

    Why Experience with 2,3-Dichloro-1,4-Naphthoquinone Matters in Practice

    Trust in chemical supply doesn’t come from paperwork alone. It grows across years and challenges—testing batches against tough incoming specs, helping researchers scale up a new process, or resolving a rare but costly shipping delay. Customers come back to us for material because they know we bring not just product, but expertise that stands up under scrutiny. Whether asked about solubility in non-polar solvents, compatibility in oxidative conditions, or behavior during a critical cross-coupling step, we rely on our manufacturing team’s direct observations and accumulated practical wisdom.

    This compound doesn’t exist in isolation. Regulatory landscapes shift, new research raises questions about long-term environmental fate, and novel applications demand tighter controls on particle size or purity profiles. Our commitment runs deeper than a product spec—by rigorously documenting every batch, investing in new purification and drying equipment, and maintaining robust relationships with both labs and production partners, we ensure customers can count on us. Documentation doesn’t lag behind process changes. Operators attending to a new purification protocol also consult with safety managers, QA inspectors, and environmental staff, so every procedural tweak keeps real-world priorities aligned: reliability, safety, and environmental responsibility.

    Direct Comparisons: 2,3-Dichloro-1,4-Naphthoquinone versus Related Compounds

    Years of experience have shown us that each naphthoquinone derivative brings its own personality to a reaction. For industrial users, the leap from benzoquinone to naphthoquinone sets the stage for deeper conjugation and altered redox behavior—this means that the naphthoquinone backbone, especially when decorated with chlorine atoms, can withstand more aggressive reaction conditions without decomposing. While other chlorinated naphthoquinones occasionally offer enhanced reactivity, they sometimes impose stricter handling needs or generate tougher byproducts to manage.

    Our customers often experiment with mono-chlorinated or higher-halo substituted analogs. Fine-tuning batch performance in these parallels comes down to striking a balance: too few halogens and you lose activity, too many and purification headaches mount. Over the years, we’ve accumulated direct evidence that the two-chlorine, 2,3-substitution pattern wins out for most scalable processes. It outpaces single-chlorine versions in electrophilic reactions, yet it doesn’t reach the volatility or unpredictability of tetra-chlorinated species, which can make storage and waste management more intense. That’s echoed in our own plant experience—stability during both storage and processing gives this compound an edge, reducing unexpected downtime and lowering the cost per use.

    Quality Assurance Rooted in Hands-on Practice

    Consistently delivering high-purity batches means building rigorous systems, both on paper and on the manufacturing line. Our laboratory staff routinely sample in-process material for multiple attributes—appearance, melting point, residual solvents, moisture, and trace-level impurities. Laboratory results trigger feedback loops straight to operators; if a test shows off-spec levels, action happens right away. Transparency from batch notes helps isolate the root cause of any deviation, allowing us to adjust temperature ladders, agitation rates, or solvent recovery steps.

    Walk into our QA lab on any production day and you’ll spot not only automated instrumentation, but also the well-worn notebooks filled out by hands that have run thousands of samples. When analytical chemists flag a sample for odd odor or cloudiness, corrective measures blend technical rigor with practical experience—tightening up vacuum stripping, tweaking crystallization timing, or even rotating storage containers to minimize oxidative exposure. Our QA built this way: high standards, hands-on accountability, and direct communication up and down the production flow.

    Customers sometimes request third-party validation or joint testing sessions. Our staff welcomes these opportunities—they serve as reality checks against our own procedures, while strengthening confidence in results. In these partnerships, technical transparency and trust carry real value, reflected in repeat orders and fast problem resolution if issues arise.

    Research Partnerships and Technical Support

    Research chemists call us not just for supply, but for direct technical input when new synthetic challenges arise. We regularly participate in joint studies, sharing not only process data but historical context for why specific approaches have worked. Questions about chlorination pathways or the quirks of 2,3-Dichloro-1,4-Naphthoquinone’s solubility in mixed solvents are routine. Our technical team fields requests ranging from batch-scale reaction optimization to assistance in developing analytical methods for trace contaminants.

    Behind every technical support inquiry runs a chain of internal expertise, years in the making. Material shipped to a research lab often comes with not only a certificate of analysis, but a direct contact for troubleshooting or consultative input. We track each request, closing the loop with validated answers and real solutions, adjusting manufacturing or packaging protocols if new patterns emerge across multiple users.

    Close relationships with academic labs enable cross-pollination of ideas: researchers sometimes report new applications that prompt us to adjust our production sequence, while we share insights about process limitations or where certain grades perform best. In these partnerships, knowledge flows both directions, ensuring our product remains a solution, not a stumbling block, in innovation.

    Continuous Improvement: Not Just a Buzzword

    Staying ahead in chemical manufacturing means avoiding complacency. Our update cycles don’t just satisfy regulations—they respond to years of customer advice, operator feedback, equipment audits, and hard-won batch data. Raw material purity standards rise whenever application needs sharpen. Plant processes expand as new drying, micronization, or blending equipment becomes available. Best practice doesn’t sit on a shelf; it evolves through everyday conversation between technical, production, and sales teams.

    By embracing customer-driven change, whether it comes through late-night troubleshooting calls or scheduled performance reviews, we uncover better ways of making and delivering 2,3-Dichloro-1,4-Naphthoquinone. Incremental tweaks—from tweaking crystallization times to adjusting shipping protocols—collectively raise quality and reduce cost, all without sacrificing worker safety or environmental compliance. Decades in the field taught us that products succeed or fail on practical results, not marketing rhetoric. Each drum shipped tells a story of practice, problem-solving, and respect for chemistry’s real-world demands.

    Looking to the Future

    2,3-Dichloro-1,4-Naphthoquinone continues to find new purpose as industry evolves. As end-market demands tighten—be it for cleaner pigments, higher-performance polymers, or greener reaction pathways—the product requires nothing less than full technical attention. Circular economy imperatives push us to explore new waste minimization strategies, invest in even tighter emission controls, and collaborate with customers on recycling or reclamation opportunities.

    Tomorrow’s requirements will almost certainly extend beyond today’s product profile. Regulatory frameworks will keep shifting, customers will keep raising the bar on purity and performance, and production economics will demand continual efficiency gains. Our history leads us to believe that partnership, transparency, and dedication to the craft of chemical manufacturing will remain the core strengths that allow this product—and our manufacturing practices—to evolve. Chemistry doesn’t stand still; neither do we.