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HS Code |
394427 |
| Chemicalname | 2,3,4-Trichloro-1-butene |
| Molecularformula | C4H5Cl3 |
| Molecularweight | 159.44 g/mol |
| Casnumber | 56051-49-7 |
| Appearance | Colorless to light yellow liquid |
| Boilingpoint | 155-158°C |
| Meltingpoint | -40°C (approximate) |
| Density | 1.35 g/cm3 (at 20°C) |
| Refractiveindex | 1.484 (at 20°C) |
| Solubilityinwater | Insoluble |
| Flashpoint | 60°C (closed cup) |
| Vaporpressure | 2.5 mmHg (at 25°C) |
As an accredited 2,3,4-Trichloro-1-Butene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 500 mL amber glass bottle, tightly sealed, labeled **2,3,4-Trichloro-1-Butene**, with hazard warnings and manufacturer details. |
| Shipping | **Shipping Description:** 2,3,4-Trichloro-1-butene should be shipped in tightly sealed, chemical-resistant containers, stored upright, and clearly labeled. Transport under cool, well-ventilated conditions, away from heat, sparks, and incompatible materials. Comply with local, national, and international hazardous materials transportation regulations, including appropriate hazard labeling and documentation. Handle with suitable personal protective equipment (PPE). |
| Storage | 2,3,4-Trichloro-1-butene should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from sources of ignition, heat, and direct sunlight. Keep away from incompatible substances such as strong oxidizers and acids. Use proper grounding and bonding to avoid static discharge. Clearly label containers and restrict storage access to trained personnel only. |
Applications of 2,3,4-Trichloro-1-Butene in Industrial Manufacturing2,3,4-Trichloro-1-butene plays a significant role in the synthesis of specialty chemical building blocks across various segments of the chemical industry. As a primary manufacturer, we supply this intermediate to multiple sectors with tailored specifications according to downstream manufacturing needs. 1. Agrochemical Synthesis: Herbicide and Fungicide IntermediateLeading agrochemical producers use 2,3,4-Trichloro-1-butene as a chlorinated alkene precursor in proprietary herbicide and fungicide active ingredient synthesis. Its well-defined structure enables selective halogenation and alkylation processes crucial for formulating actives such as substituted pyridine and pyrimidine derivatives. Strict batch traceability and impurity control ensure compliance with agricultural health regulations. Producers adjust usage ratios based on the targeted ring-substituted profiles during multi-step synthesis. Industry compliance standards
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2. Pharmaceutical Intermediate for Antiviral and Anticancer APIsSpecialty API manufacturers incorporate 2,3,4-Trichloro-1-butene in the custom synthesis of building blocks for both small-molecule antivirals and anticancer drugs. It is used in substitution and ring closure steps to introduce chlorine atoms at defined positions, critical for the bioactivity of certain heterocyclic scaffolds. Pharmaceutical-grade lots maintain ultralow impurity thresholds, documented batch records, and tight process control to satisfy global drug registration requirements. Industry compliance standards
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3. Fine Chemical Intermediate for Polymer CrosslinkersHigh-performance polymer and resin formulators use 2,3,4-Trichloro-1-butene as a reactive crosslinker precursor. The unique trichloroalkene functional group facilitates the formation of specialized crosslinking agents via addition or substitution reactions, improving the heat and chemical resistance of engineered resins. Optimal feed rates and reaction temperatures are set to control molecular weight distribution and end-group composition. Industry compliance standards
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4. Intermediate in Custom Synthesis of Performance AdditivesManufacturers of lubricant, plastic, and paint additives utilize 2,3,4-Trichloro-1-butene for constructing functionalized performance enhancers. The material’s chlorine-substitution pattern is leveraged in targeted syntheses, such as introducing flexible or flame-retardant side groups on additive molecules. Feedstock ratios are carefully optimized to ensure functionalization efficiency and minimize side product generation. Consistency in physical parameters is maintained for downstream blending in finished formulations. Industry compliance standards
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5. Synthesis of Photoresist Monomers for Semiconductor ManufactureChemical suppliers to the electronics industry use this raw material to prepare chlorinated monomers incorporated in high-purity photoresist formulations. The high electron density imparted by the three chlorine atoms influences resist sensitivity and fine feature definition during micro-lithographic etching. Ultrapure batches and narrow composition ranges meet the severe requirements of semiconductor material quality systems. Industry compliance standards
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Manufacturing 2,3,4-Trichloro-1-Butene as a direct producer gives us a front-row view on how this compound shapes specialty chemicals. With the structure C4H5Cl3 and a model known in the market as 2,3,4-TCB-1-ene, this chemical answers the need for both reactivity and selectivity among butene derivatives. For years, our teams have focused on producing this compound with consistent purity so downstream processors count on predictability whether they work in pharmaceutical synthesis, agricultural intermediate development, or advanced chemical research.
Our production lines run batches of 2,3,4-Trichloro-1-Butene at controlled atmospheres, keeping the water content and organic residue in check. We know once a product leaves our facility, whoever receives it depends on stable composition. Industries that synthesize more complex molecules often turn to this butene for its unique reactivity at the trichlorinated positions. Our technical staff members have examined this compound side-by-side with mono- or di-chlorinated butene options, and the pattern of functional group placement across the carbon chain unlocks new synthesis routes. In practice, this can shorten multi-step procedures or improve yields—both highly prized results among manufacturers trying to reduce production time and lower costs.
2,3,4-Trichloro-1-Butene isn’t a shelf-filler; each drum represents a decision by chemists who know what chain length and halogen arrangement buy in terms of reactivity. Over years of conversations with technical buyers and production chemists, we’ve heard how this butene handles as a coupling agent, a halogenated building block, and, in regulated labs, even as a model compound for studying addition and substitution.
In agrochemical synthesis, for instance, the three chlorine atoms along the chain create a versatile platform. Downstream manufacturers have improved their processes for selective substitution, introducing amines or other nucleophiles at specific carbons. This feeds directly into pesticide intermediates or specialty protective agents. Pure 2,3,4-Trichloro-1-Butene sidesteps problems sometimes reported with 1,2-dichlorobutene or 3,4-dichlorobutene, where reaction control can slip, leading to product variability. Our customer feedback makes it clear: predictable chlorination helps reduce waste, especially when projects involve high-volume batch runs.
Pharmaceutical research teams look for similar reliability. Multi-step synthesis courses rely on tight control over starting materials, not just for product quality but for regulatory compliance. With 2,3,4-Trichloro-1-Butene, they gain a platform for introducing complexity into small-molecule drug candidates, in a way that leaves less room for side reactions that complicate purification or fail to scale.
Our hands-on processing knowledge sets us apart from traders or secondary handlers. Years upgrading our purification columns and fine-tuning distillation steps cut down on unpredictable impurities that otherwise prompt rework or equipment cleaning downstream. Rather than filtering finished batches through bulk adsorbents, we tune process temperature and residence times so the output meets strict purity benchmarks from the start.
On production days when 2,3,4-Trichloro-1-Butene is running, technicians monitor every drum for both visual and chromatographic signals—ensuring each meets accepted isomer ratio and water content indicators. Reports and tracking become more meaningful for end users aiming to validate their supply chain from raw material to finished product.
2,3,4-Trichloro-1-Butene stands out for the specialty positions of its chlorine atoms. With chlorines at the 2, 3, and 4 positions along the butene chain, selectivity in chemical reactions increases compared to options such as 1,2-dichlorobutene or 1,3-dichlorobutene. The extra chlorine, specifically positioned, allows for targeted substitutions, supporting advanced synthesis where functional diversity is necessary.
Manufacturing partners talk often about the challenges of using the more common mono- or di-chloro alternatives. Mono-chlorobutene, for example, usually reacts too readily or produces mixtures hard to separate. Di-chlorinated variants sometimes stall in substitution steps, requiring harsher conditions or excess reagents, which then impact environmental controls or downstream processing costs. The tri-chloro arrangement on 2,3,4-Trichloro-1-Butene avoids many of those headaches, giving the operator greater freedom to perform transformation reactions in more forgiving conditions, whether batch or continuous process.
We’ve met specialty polymer and surfactant producers who previously struggled with inconsistent conversion rates or uneven incorporation of functional groups. The move to our 2,3,4-Trichloro-1-Butene, with assured chlorination at each targeted carbon, provided a path forward. This saved them not only in raw material waste, but also in time tracking down causes of off-spec product.
Handling 2,3,4-Trichloro-1-Butene brings practical challenges, particularly regarding stability and containment. Direct experience dictates strict control over temperature and transfer equipment. Unlike less chlorinated butenes, this molecule exhibits greater volatility and demands sealed, corrosion-resistant storage. Our facility implemented double-valved drum systems for liquid transfer, reducing loss and environmental risk.
In manufacturing, we’ve found regular employee training to be just as crucial as equipment updates. Spills can escalate rapidly with chlorinated intermediates, so process controls and fast incident response keep both operators and local infrastructure safe. During transport season, coordination with certified logistics companies ensures no part of the supply route is left to chance, minimizing delays and exposure risk.
The environmental footprint of chlorinated intermediates remains an ongoing focus. Our approach balances efficiency with responsible waste treatment. Residual streams receive on-site neutralization in a closed reactor, followed by expert analysis before discharge. By designing our system this way, we satisfy local environmental agencies and manufacturer partners who face parallel compliance requirements downstream. These practices support not only safer product handling but also enhance transparency to customers seeking reliable supply partners.
Working directly with buyers and research teams over the past decade, we’ve adapted our offering for the realities faced at every stage of the supply chain. Early shipments of 2,3,4-Trichloro-1-Butene sometimes fell short in stability if temperature spikes occurred in transit. Since then, we developed “just-in-time” batch production for some partners, sending smaller, more frequent shipments to align more closely with inventory turn and avoid stock expiration. This fine-tuning led to reduced order lead times, fewer product returns, and higher satisfaction among specialty chemical buyers who manage sensitive formulations.
Shared problem-solving also led to upgraded analytical documentation. With reports covering not just GC profile but trace impurities, water levels, and container history, downstream partners maintain confidence in every drum received. This documentation doesn’t just please auditors—it helps end users avoid unplanned downtime caused by uncertain raw material quality.
In the years spent refining our formulation and delivery practices for 2,3,4-Trichloro-1-Butene, one lesson stands out: supply chain reliability is built in production, not paperwork. Quality checks are timed close to the final drum or ISO container, not just in early process samples. We coordinate regularly with customers to understand how long the product remains in storage at their facility, so packaging matches the expected life cycle.
By using nitrogen blanketing and food-grade seals, we reduce the risk of atmospheric moisture seeping into containers. On some occasions, customer labs faced cloudy product or uneven purity due to condensation from unlined steel packaging. Our shift to polymer-coated drums and improved headspace management effectively ended those complaints. These small changes in the manufacturing pipeline cut down on customer rework, and the lessons pass from one generation of process engineers to the next inside our facility.
Years after we began offering 2,3,4-Trichloro-1-Butene, input from applied research firms keeps shaping our improvement efforts. Feedback from users in synthetic organic chemistry has shown consistent spectrum correspondence and minimal batch-to-batch variability. As a result, process engineers gained the confidence to plan large-scale syntheses without resorting to excess raw material as a safety margin.
In downstream synthesis, the unique electronic profile from having three chlorines on the butene system changes how nucleophiles attack, compared to alternatives. Lab trials run at contract research organizations demonstrated higher selectivity for targeted substitution, especially on shorter reaction timelines. Pharmaceutical development groups, in particular, cited reduced byproduct load in post-reaction filtration—vital for minimizing both operational cost and environmental treatment overhead.
We keep on top of new regulatory guidance, adjusting both internal cleaning protocols and end-user advisories as legislation evolves. By sharing best-practice handling guides and product change notifications, our partners stay compliant through changing requirements without the need for extra third-party audits.
Market demand for halogenated intermediates fluctuates with global trends in agriculture, pharmaceuticals, and material science. As a manufacturer, tracking these shifts means adjusting raw material buying and batch scheduling throughout the year. When global supply strains occur for key precursors, steady communication with upstream suppliers helps us predict bottlenecks before customer orders run short.
On the sustainability front, direct engagement with environmental agencies prompted us to invest in vapor recovery from storage tanks and enclosed reaction systems. Rather than venting excess gases or liquid purge streams, we route them into in-plant neutralization units or material recycling operations. The decision to handle things this way stemmed from customer requests and years witnessing the impact of chemical leaks in industry news.
Customers pursuing green chemistry initiatives have asked about alternative feedstocks. While halogenated butenes remain petrochemical in origin, we continue to assess pilot projects using recovered industrial chlorides. Though technological and cost hurdles remain, close partnership with innovation labs allows us to keep options open when new methods reach commercial feasibility.
Shipping 2,3,4-Trichloro-1-Butene in high-volume containers involves careful planning. Thermal cycling creates expansion and contraction, so drum selection and headspace calculation must anticipate local climate swings in the receiving region. After our teams observed several incidents of product thickening under extreme temperature exposure, we started using insulated pallets during peak summer and heat-traced storage bays during winter.
Besides packaging, direct dialogue with end-users about on-site integration proved valuable. Large batch operators sometimes need blanketing gas hookups compatible with their transfer equipment. By standardizing our drum flange design to fit both U.S. and international connections, we shortened their prep time and improved transfer safety. Such changes only become clear through frontline experience, not through abstract design.
We take extra steps in verifying each outgoing batch, running full-spectrum analysis beyond the typical GC-FID. Customers deploying 2,3,4-Trichloro-1-Butene for high-purity applications require clear assurance on residual solvent, isomer ratios, and trace element content. Our quality control lab includes periodic cross-validation with third-party labs, so customers and auditors alike receive data backed by independent checks.
Technicians capture detailed process logs for every batch run. These logs become a reference for troubleshooting if a user site reports unexpected results. In such cases, we can pinpoint whether process parameter drift, packaging failure, or raw material substitution played a role.
The challenge of producing a high-purity chlorinated intermediate grows as environmental and safety requirements tighten year after year. By layering process automation with experienced operator oversight, we maintain quick response capability during upsets without losing control of emissions or quality.
We’re examining continuous reaction pathways as part of technology upgrades, which promise less variability and lower waste than traditional batch runs. Early results show promise for raising yields and cutting turnaround times for our frequent buyers, particularly those scaling up production for new product launches.
Advances in reaction modeling, including computational tools, also allow us to anticipate impurity formation and adjust batch conditions in real-time, streamlining the path from raw material to customer.
Producing 2,3,4-Trichloro-1-Butene carries a distinct set of challenges and responsibilities. Over the years, customer demand for transparency, reliability, and technical support has steered our operation toward greater rigor and more open communication. Our investment in improved packaging, real-time batch monitoring, and attentive documentation comes from years on the manufacturing floor—where every shipment matters to a broad range of industries.
Reliance on direct feedback, regulatory cues, and on-the-ground collaboration with buyers shapes our approach, keeping 2,3,4-Trichloro-1-Butene a dependable solution for complex synthesis. Whether the need centers on agricultural, pharmaceutical, or material science applications, each batch produced reflects the lessons of experience and ongoing conversation between manufacturer and end user.