Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

1-Propanethiol

    • Product Name 1-Propanethiol
    • Alias Propyl mercaptan
    • Einecs 214-478-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    380858

    Cas Number 107-03-9
    Molecular Formula C3H8S
    Molar Mass 76.16 g/mol
    Appearance Colorless liquid
    Odor Strong, unpleasant odor (like rotten eggs)
    Melting Point -110 °C
    Boiling Point 67 °C
    Density 0.832 g/cm³ (20 °C)
    Solubility In Water Slightly soluble
    Flash Point -18 °C (closed cup)
    Vapor Pressure 410 mmHg (20 °C)
    Refractive Index 1.434 (20 °C)
    Autoignition Temperature 368 °C
    Pubchem Cid 7929
    Un Number 2402

    As an accredited 1-Propanethiol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1-Propanethiol is supplied in a 500 mL amber glass bottle with a sealed cap and hazard labeling for safe laboratory handling.
    Shipping 1-Propanethiol should be shipped in tightly sealed containers made of compatible materials, protected from physical damage and away from sources of ignition. It should be transported under proper ventilation, with correct hazard labeling as a flammable and toxic substance. Regulatory guidelines (such as UN2347, Class 3/6.1) must be strictly followed.
    Storage 1-Propanethiol should be stored in a cool, dry, well-ventilated area, away from sources of heat, sparks, or open flames. Keep the container tightly closed and protected from light. Store separately from oxidizing agents, acids, and bases. Use proper, labeled containers made of compatible materials, and avoid contact with copper or copper alloys. Ensure spill containment and provide access to safety equipment.
    Application of 1-Propanethiol

    Applications of 1-Propanethiol in Industrial Manufacturing

    We supply 1-Propanethiol (n-propyl mercaptan) for specialized industrial applications where its unique reactivity and organosulfur characteristics are critical to downstream product performance. Below, we detail established application sectors, focusing on technical use cases, compliance adherence, operational processing, and end product formats that rely on this material.

    1. Agrochemical Synthesis: Selective Herbicide Intermediates

    In agrochemical manufacturing, downstream users employ 1-Propanethiol as a key intermediate in synthesizing thiol-containing herbicide actives. The compound introduces sulfur moieties required for target molecule selectivity during active pharmaceutical ingredient building steps within batch and continuous production schemes. High purity requirements are essential to ensure process stability and downstream bioactivity, making origin traceability and supply-chain quality controls fundamental in pesticide formulation lines.

    Industry compliance standards

    • FAO/WHO Joint Meeting on Pesticide Specifications (JMPS)
    • ISO 9001:2015 Quality Management for agrochemical manufacturing
    • REACH (EC) No 1907/2006—Substance Registration
    • China GB 2763 Maximum Residue Limits in Foods — relevant for downstream use

    Typical usage ratio

    • 5–18% by mass in intermediate coupling stages, adjusted based on target herbicide molecule and reaction scale; optimization relies on desired sulfur incorporation and side reaction minimization.

    Downstream process integration

    • Charged in as a nucleophilic sulfur component at the initial or mid-phase of heterocycle or thioether linkage formation, usually under controlled temperature and inert gas conditions before subsequent purification.

    Final product types

    • Sulfur-containing selective herbicides (e.g., thiocarbamate and thiourea actives)
    • Agrochemical technical concentrates for formulation houses
    • Pre-formulated spraying solutions (after further finishing steps)

    2. Aroma and Flavor Compound Production (Industrial Non-food Use)

    Industrial fragrance and flavor facilities apply 1-Propanethiol in the formulation of strong, characterful base notes for animal feed additives and odor marker solutions. It serves as a key precursor for the synthesis of organosulfur aroma compounds, especially in streams where potent, controlled-release scent features are crucial, but not intended for direct food consumer contact. Precision in impurity management and traceability through batch records is required to satisfy quality and safety expectations for contact materials.

    Industry compliance standards

    • FEMA (Flavor and Extract Manufacturers Association) non-food technical grade protocols
    • ISO 9001 traceability for feed additive processing
    • EU Regulation (EC) No 1831/2003 for feed additive use
    • OSHA 29 CFR 1910.1200, chemical hazard labeling and safety data

    Typical usage ratio

    • 0.01–1% by mass in aroma intermediate blends; exact rate varies by scent intensity requirement and downstream offsetting components.

    Downstream process integration

    • Added as a raw material for alkyl mercaptan synthesis, and incorporated in controlled esterification or oxidation reactions for desired aroma compound generation, then blended into base notes for animal feed aroma enhancers or technical scent markers.

    Final product types

    • Feed additive aroma blends (non-food or pet nutrition only)
    • Industrial odorant marker solutions (e.g., detector calibration)
    • Environmental scent monitoring reference materials

    3. Gas Odorization: Natural Gas and LPG Safety Markers

    Utility-grade supply sectors and odorant formulation plants introduce 1-Propanethiol as one of several calibrated compounds to impart warning scents to otherwise odorless fuel gases. Accurate metering, stability, and purity control prevent pipeline corrosion, customer complaints due to off-odors, or disruptions from volatility. Downstream pipeline companies require fully traceable sourcing, strict compositional transparency, batch documentation, and rigorous analysis to comply with national odorization requirements.

    Industry compliance standards

    • EN 13725 (European Reference Method for Odor Concentration Measurement)
    • NFPA 58 Liquefied Petroleum Gas Code
    • 49 CFR Part 192.625 (US DoT Pipeline Safety: Odorization of Gas)
    • ISO 9001:2015 quality management throughout dosing and supply chain

    Typical usage ratio

    • 2–25 mg/m³ in delivered fuel gas, defined by pipeline length, anticipated dilution, and regulatory minimum odorant threshold detection requirements.

    Downstream process integration

    • Injected in the odorization skids or dosing systems at city gate stations or LPG bottling points; blending with secondary odorants (e.g., tert-butyl mercaptan) to calibrate final scent signature per jurisdictional rules.

    Final product types

    • Odorized natural gas (in transmission pipelines)
    • Odorized LPG for industrial and residential use
    • Calibration standards for pipeline leak detection systems

    4. Pharmaceutical Intermediate Manufacturing: Thioether Linkage Synthesis

    Original API and advanced intermediate manufacturing facilities utilize 1-Propanethiol to introduce propylthio groups required for pharmaceutical moieties, particularly in small-molecule drugs with synergistic organosulfur scaffolds. Strictly controlled GMP environments demand accurate batch-to-batch quality, low impurity profiles, and full reagent qualification to safeguard final product purity and regulatory approval for human or animal applications.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • US Pharmacopeia/NF for process intermediates
    • EU GMP Directive 2003/94/EC for medicinal production
    • ISO 17025 analytical testing certification for QC labs

    Typical usage ratio

    • 1–5 molar equivalents relative to halo-precursor; specific use rate depends on selectivity of target API and side product minimization requirements in the synthesis.

    Downstream process integration

    • Added after precursor activation or amidation procedures as the nucleophilic reagent for thioether linkage closure, followed by precise work-up and in-process analytical testing for intermediate qualification.

    Final product types

    • Advanced thioether intermediates for API synthesis
    • On-patent and off-patent small molecule APIs with sulfur fragments (e.g., propylmercapto analogs)
    • Veterinary pharmaceutical precursors

    5. Rubber Processing Chemicals: Sulfur-Donor Component in Accelerators

    Rubber compounding operations and specialty chemical formulators select 1-Propanethiol as a sulfur-donor agent in certain thiazole or sulfenamide vulcanization accelerator systems. Its controlled release of sulfur in curing stages helps optimize crosslinking kinetics and finished rubber properties. Proper industrial hygiene procedures and accurate dispensing prevent premature vulcanization and improve physical attributes of automotive and industrial rubber goods.

    Industry compliance standards

    • ASTM D3182/ISO 2393 for rubber compounding
    • REACH (Annex XVII) compliance for safe chemical handling in EU
    • ISO 9001:2015 process controls at mixing facilities
    • Corresponding national occupational health and safety codes

    Typical usage ratio

    • 0.05–0.3 phr (parts per hundred rubber) within accelerator blends; dosage optimized for required cure speed and mechanical characteristics.

    Downstream process integration

    • Incorporated during mastication or final mixing in open mills or internal mixers along with other curatives before calendaring, extrusion, or injection-molding stages, followed by hot curing under pressure.

    Final product types

    • Automotive tires (specific tread or sidewall applications)
    • Industrial conveyor belts
    • Specialty rubber rolls and elastomeric gaskets
    Free Quote

    Competitive 1-Propanethiol prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Understanding 1-Propanethiol: Insights From the Production Floor

    The Value of 1-Propanethiol in Industrial Chemistry

    Most people haven’t heard of 1-Propanethiol, but it makes its mark all the way from flavor synthesis to specialty chemicals manufacturing. This isn’t a fancy, complicated compound; 1-Propanethiol brings real power through its simple molecular arrangement. Known chemically as C3H8S, it stands out in the thiol family because the three-carbon chain carries a strong yet manageable odor profile and shows impressive reactivity in versatile organic syntheses. Because we handle the entire process, from sourcing propylene feedstock to fine purification, we can vouch for its true character and performance.

    Consistent Production Yields Reliable Results

    At our facility, we do not delegate or outsource production. This means every kilogram can be traced through our hydrogenation units, distillation towers, and storage—no uncertainty and not a drop wasted. We do not cut corners at any stage. The work begins with carefully controlled alkylation of hydrogen sulfide under pressure, employing equipment built to robust industrial standards. This chemistry demands care, and we meet it head-on every day with operators who have handled reactive sulfur compounds throughout their careers. The end result comes through as a clear liquid with a distinct, familiar odor signaling authentic 1-Propanethiol. Purity checks confirm the material consistently hits GC standards that the market expects.

    Key Specifications: Our Approach in Numbers

    We focus on 1-Propanethiol available in technical and high-purity grades. For most synthesis routes, customers rely on our >99.0% product, where water, by-products, and residual organics fall under tight thresholds. We achieve this not just by mechanical separation but by continuous tweaking, monitoring batch to batch, and running multiple onsite analyses. The boiling point hovers around 67 °C at ambient pressure—our tanks and loading bays are designed around this specification, so handling and shipping remain safe and predictable.

    Refining propanethiol is less about theoretical metrics and more about steel-willed discipline on the shop floor. We do not ship unless gas chromatography and odor panel confirmations meet our internal expectations. Our confidence builds over years, with processes refined through trial, not guesswork. Customers who visit can see the effort: freshly distilled product comes off the line, cools in airtight systems, and gets packed inside drums or IBCs clean and dry, every time.

    Industrial Uses Shaped by Practicality

    Our main buyers use 1-Propanethiol chiefly for chemical synthesis. For example, in pharmaceutical intermediates, the propyl group confers desirable flexibility in constructing larger molecules. The material shows up in certain agrochemicals, where selective thiol reactivity creates specialty compounds that otherwise stay out of reach. We’ve supplied custom-engineered grades for flavors and fragrances, too, where only a few grams alter the background note of savory flavors during Maillard reactions or add backbone to commercial flavorings for food processing. These are not bulk markets, but they demand consistency—something only a manufacturer who controls every valve and pipeline can guarantee.

    In research settings, universities and R&D labs prize 1-Propanethiol for developing catalysts and testing surface modification reactions. The ability to rapidly add a SH group under mild conditions unlocks applications not just in traditional organic synthesis but in cutting-edge material science—think nano-coatings, polymer stabilization, or even controlled-release pharmaceuticals. Our direct insight into customer application experiments provides important feedback: minor impurities in our product can derail entire tests, so we adjust purification methods based on real customer experiences, not theoretical purity.

    Handling and Safety From a Manufacturer’s Perspective

    We cannot talk about 1-Propanethiol honestly without mentioning its smell—sharp, penetrating, sulfur-heavy. This isn’t a product to be handled by accident or with poor ventilation. On our site, containment is critical. Double-sealed hoses, direct-draw sampling, and sulfur-resistant gloves create a work environment where exposure risks drop drastically. Our approach to safety isn’t driven by paperwork but from working alongside operators who know what a single leak means. The smell alone would clear a room in seconds. Training focuses on equipment checks, odor detection thresholds, and active monitoring: no exceptions, no half-measures.

    Offsite, once drums leave our yard, we recommend buyers pay close attention to storage and handling advice honed over decades. Drums stay sealed unless in use, storage areas must be well-ventilated, and emptying lines call for positive displacement pumps with proper seal material. We rarely hear of incidents because our customers take handling as seriously as we do—but anyone working directly with 1-Propanethiol respects what happens when you don’t follow the rules.

    Comparing 1-Propanethiol to Other Thiols

    People often ask how 1-Propanethiol stacks up against other thiols like 2-Propanethiol or Ethanethiol. From a manufacturer’s viewpoint, each thiol tells a different story. Ethanethiol brings volatility and the strongest possible odor; its two-carbon backbone makes it ideal for applications like odorization of natural gas, but the smell overpowers everything in the plant. 1-Propanethiol, in contrast, delivers practical reactivity with a little more control on the volatility front—lower vapor losses, easier containment, and more straightforward separation from by-products. Chemical reactivity remains high, allowing downstream processes to add or modify functional groups with confidence.

    2-Propanethiol (isopropyl mercaptan) emerges during similar synthesis routes, but it features a branched structure that changes both odor and performance in synthesis. The steric hindrance of its isopropyl group gives different selectivity in certain reactions. Between these, 1-Propanethiol often provides the blend of manageable odor, moderate volatility, and reliable backbone for further chemistry. Because our plant can run both linear and branched isomers, we’ve seen directly how subtle differences in structure change everything from distillation to final uses.

    Market Realities: What Customers Actually Need

    Trade journals talk a lot about ‘market demand’ or ‘driving efficiencies’, but on our production floor, we hear more practical requests. Customers want two things: material that works every batch, and answers when something goes off-spec. 1-Propanethiol does not sell in commodity volumes like gasoline components, but its buyers tend to return year after year, trusting us to deliver precisely what they ask for. We receive challenge samples and requests for low-water, low-acid grades—sometimes odorless, always packed for easy transfer. Our facility tracks every lot, runs additional in-house testing for long-term partners, and listens when anyone says the product changed outcome in their own process. This direct feedback closes the circle between plant and end-user.

    Unlike distributors, we do not blend batches or reload cargos from third-party tanks. What leaves our gate was made here, by our people, in our equipment. Anyone who’s had a project stall from off-grade mercaptan knows those realities deeply. We exist to remove that uncertainty, with traceable, accountable material from propylene input to packed drum outbound.

    Improving Quality Over Decades, Not Quarters

    Our relationship with 1-Propanethiol didn’t start with spreadsheets and market forecasts. It grew from building, troubleshooting, and modifying a real chemical plant through years of hands-on work. There are no shortcuts for experience gained from hundreds of batches, unexpected run-stoppers, and deep-clean maintenance that only comes after midnight scrambles on the production line. Each process change—updated dewatering tanks, improved column reflux controls, better sulfur handling—comes about from small, sometimes costly lessons that add up to reliable output over decades.

    We believe customers see the difference. Some batches carry trace markers from upstream propylene, which our in-house GC picks up within seconds. It’s tempting to think that a single impurity or a hint of moisture won’t matter in downstream chemistry, but we have seen first-hand how those small problems snowball. Over the years, we’ve invested in new drying beds, upgraded filtration, and better vapor recovery systems not only because it meets a spec on a paper order, but because it matters to real people’s real processes.

    Supply Chain as a Responsibility, Not a Buzzword

    People rely on 1-Propanethiol to show up when they need it, at the right spec, and packed in clean, secure containers. Our plant runs with tough supply chain standards; it’s not just a matter of moving inventory. If a tank is out of service, or if we spot an unexpected dip in quality mid-run, we stop and fix it. Our steady production means customers do not sit idle waiting for imports or unknown-origin drums. Many long-term customers keep direct lines with our production crew, not just a logistics manager, because they know answers come faster when they talk to the people who make the product.

    As pressures on supply change—transport challenges, regulatory updates, or unexpected feedstock shortages—we keep lines of communication open. We believe in honest updates, flagging any risk before a shortage affects a project start. With regional networks for surges or backup raw materials, we build in redundancies rather than shuffle risk down the chain. If we promise a batch, we deliver, and we don’t walk away from questions that come up post-delivery.

    Regulatory Compliance from the Plant Worker’s View

    Compliance is not a formality for us. We spend real time training operators, updating process controls, and keeping up with changing sulfur compound regulations. 1-Propanethiol, handled wrong, can create environmental headaches. We run leak detection, emissions control, and containment systems continuously—not once per year at inspection but every day. Anyone who’s worked with these materials knows that the rules protect not only the environment but also every worker on the line.

    Because regulations stay dynamic, we keep both plant records and staff knowledge up to date. There is no shortcut for having a team ready to adjust if local or national rules shift. Our plant doesn’t just meet existing compliance standards—it’s set up to react quickly if next year’s standards raise the bar.

    True Cost: Beyond the Invoice

    The market price of 1-Propanethiol might get listed in industry reports, but the true cost ties back to reliability, safety, and the actual process outcome. We have watched too many projects stumble elsewhere from slow shipments, off-grade batches, or mystery impurities that creep in during blending. Our team gets calls from technical directors, not just purchasing departments, when unforeseen changes crop up. They ask straightforward questions: how much water sits below 100 ppm, how stable the SH group stays over a month, or whether an unusual odor note could hint at contamination. The answers only come easily because every step—from incoming raw material to the outgoing valve—is seen and touched by our crew.

    We now see customers factor in more than just bulk cost or delivery time. They understand what reliable 1-Propanethiol means for their own schedule. If the first reaction works, the entire project stays on track; if the base material slips, every step past that point gets harder. By handling everything in one place, we remove those variables and keep our partners’ trust longer than a single shipment ever could.

    Solutions for the Future of Specialty Sulfur Chemistry

    Innovation in our industry rarely shows up as a headline. More often, it builds slowly—new filters, better process analytics, or smarter control schemes that move quality data from instrument to operator without delay. As demand for specialty intermediates changes, new downstream customers appear in electronics, renewable materials, or fine pharmaceutical research. We work with these partners to tweak both grade and handling, adding custom packaging or modified stabilization if needed.

    Our knowledge grows with each project. Once, a customer asked for a nonstandard water content and we had to alter drying towers, rework cleaning schedules, and monitor product stability deeper into the supply chain. These internal changes turn into permanent upgrades; the next request draws on improved systems. We don’t chase trendy ‘solutions’—we solve for real-world obstacles our own workers face. Investments focus on reliability and scrutiny, not advertising slogans.

    We also stay alert on sustainability and waste reduction. Sulfur chemistry carries tough questions about odor, energy use, and emissions. Plant upgrades focus on real reductions—reclaiming vapor, neutralizing washwater, and capturing off-spec material for recovery instead of disposal. Years from now, the market will likely demand even stronger performances on waste and energy. The work must get done far away from boardrooms and review slides, but if the process fits today’s needs, upgrades flow naturally into tomorrow’s.

    Closing Thoughts From the Production Line

    1-Propanethiol has built a quiet but vital corner in modern chemistry. Everything we know about this material, we learned day by day in a real plant, where odor tells you if a seal holds and every GC trace carries history from yesterday’s run. We see 1-Propanethiol not just as a product, but as a promise—if the right compound lands in the right hands, work gets done that benefits every link in the chain. If mistakes get made, the best solution is to confront them at the source—fix them so they don’t reach the end-user.

    Anyone who uses 1-Propanethiol at scale appreciates the difference a genuine manufacturer brings. We carry the knowledge not from sales brochures but from boots on the concrete, tools in hand, and careful attention to each line of the process. Across every batch and every year, we strive to give the market a material as reliable as the people who make it.