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1-Diethylamino-4-Aminopentane

    • Product Name 1-Diethylamino-4-Aminopentane
    • Alias 1,4-DEAAP
    • Einecs 221-573-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    500873

    IUPAC_Name 1-(Diethylamino)pentan-4-amine
    CAS_Number 72634-41-6
    Molecular_Formula C9H22N2
    Molecular_Weight 158.29 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling_Point 217 °C (estimated)
    Density 0.84 g/cm³ (estimated)
    Melting_Point Unknown
    Solubility_in_Water Miscible
    pKa Estimated 10.0-10.5
    Flash_Point 85°C (estimated)
    Synonyms N,N-Diethyl-4-aminopentylamine

    As an accredited 1-Diethylamino-4-Aminopentane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging is a 250-gram amber glass bottle, tightly sealed, labeled with hazard symbols and the name "1-Diethylamino-4-Aminopentane."
    Shipping 1-Diethylamino-4-aminopentane is shipped in tightly sealed chemical containers to prevent moisture and air exposure. It must be labeled according to hazardous material regulations, and transported under cool, dry conditions. Protective packaging and documentation should accompany each shipment, ensuring compliance with local, national, and international chemical safety transportation standards.
    Storage **1-Diethylamino-4-Aminopentane** should be stored in a tightly sealed container, away from moisture, heat, and direct sunlight. Keep in a cool, dry, well-ventilated area, separated from oxidizing agents and acids. Ensure all containers are clearly labeled and handle under a chemical fume hood if possible. Follow all safety guidelines for storing amines and potentially hazardous organic chemicals.
    Application of 1-Diethylamino-4-Aminopentane

    Applications of 1-Diethylamino-4-Aminopentane in Industrial Manufacturing

    1-Diethylamino-4-aminopentane serves as a multi-function intermediate in specialized chemical synthesis. We supply this compound to global industry leaders for advanced formulations in high value sectors. Our technical support covers regulatory compliance, dosage formulations, and manufacturing integration for these specific downstream scenarios.

    1. Pharmaceutical Intermediate in Active Pharmaceutical Ingredient Synthesis

    Pharmaceutical manufacturers select 1-Diethylamino-4-aminopentane for use as a key building block in the multi-step synthesis of certain CNS active agents and antihypertensive medications. The compound’s amine functionality enables targeted alkylation and amide coupling during controlled API production. Use mandates strict batch traceability, residue monitoring, and verified impurity profiles to satisfy regulatory agency inspections. Both custom and standard processes employ this material under clean-room protocols with automated feed systems.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for APIs
    • 21 CFR Part 211 (US FDA cGMP regulations)
    • European Pharmacopoeia (monograph compliance for APIs)
    • WHO GMP Certification for international markets

    Typical usage ratio

    • 0.5–2.5% relative to the starting material mass; adjusted by target molecular yield and reaction route optimization

    Downstream process integration

    • Charged as a raw amine feedstock in the first or mid-stage condensation step
    • Enters directly into batch reactors under nitrogen
    • Incorporated by automated metering in validated GMP suites

    Final product types

    • Active pharmaceutical ingredients (APIs) for cardiovascular or neurological drugs
    • Advanced intermediates for contract development pipelines
    • Regulatory-submitted APIs for ANDA/NDA filings

    2. Corrosion Inhibitor Component in Metalworking Fluids

    Producers of soluble oil, semi-synthetic, and full-synthetic metalworking fluids formulate with 1-Diethylamino-4-aminopentane to enhance amine-based corrosion inhibition. Precise dosing prevents ferrous ion oxidation and stabilizes pH in high-load machining operations. The material must comply with workplace health regulations and environmental approvals, including registration for use under regional chemical inventory systems. Custom formulation tuning accommodates both direct coolant blending and post-synthesis neutralization stages.

    Industry compliance standards

    • OECD chemical registration (e.g., REACH, TSCA)
    • TRGS 611 (Germany) for water-miscible metalworking fluids
    • ASTM D4627-16 test methods for corrosion inhibitors
    • ISO 4871 occupational safety limits

    Typical usage ratio

    • 0.25–1.0% in concentrate phase; adjusted by coolant type and end-user protection goals

    Downstream process integration

    • Added during final blending in stainless mixing tanks
    • Dosed at the chemical concentrate mixing stage
    • Compatibility checked with biocides, defoamers, and other amines

    Final product types

    • Low-foam cutting fluids
    • High-performance synthetic machining coolants
    • Specialized semi-synthetic emulsions for high-pressure operations

    3. Ion Exchange Resin Manufacturing

    Ion exchange resin facilities consume 1-Diethylamino-4-aminopentane in the post-crosslinking amination process for weak base resin production. The compound provides a diethyl functional group suited for unique selectivity in water treatment and sugar refining applications. Operators conduct rigorous leachability testing and monitor amine content to meet potable water and food contact standards. Strict process documentation ensures batch reproducibility and controlled residual monomer content.

    Industry compliance standards

    • NSF/ANSI 61 (Drinking Water System Components – Health Effects)
    • EU Regulation (EC) No 1935/2004 (Materials in contact with food)
    • ISO 9001:2015 (for QC batch release)
    • FDA 21 CFR 173.25 (Ion exchange resins in food processing)

    Typical usage ratio

    • 3.0–8.0% w/w relative to polymer mass; refined by target amine exchange capacity

    Downstream process integration

    • Charged as part of the post-crosslinking functionalization
    • Grafted onto chloromethylated resin beads at 60–85°C
    • Excess is quenched and removed by wash cycles

    Final product types

    • Weak base anion exchange resins
    • Demineralization resins for potable water plants
    • Sugar purification resin beads

    4. Polyurethane Catalyst Precursor

    Polyurethane system formulators use 1-Diethylamino-4-aminopentane as a reactive amine precursor in multi-component catalyst blends. The compound initiates and controls polyol/isocyanate reactions, crucial in flexible and rigid PU foam applications. All processing observes sector-specific environmental and workplace exposure limits, including regulatory record-keeping for catalyst content and emissions. Ratio adjustments account for polyol composition, isocyanate index, and required curing speed in both slabstock and molded products.

    Industry compliance standards

    • REACH Annex XVII (Amine use in PU reactions)
    • OSHA 40 CFR 1910 (worker exposure monitoring)
    • China GB/T 26572 (PU foam catalyst restrictions)
    • ISO 9001 (production QC documentation)

    Typical usage ratio

    • 0.02–0.15% on total system weight; refined for foam structure and density requirements

    Downstream process integration

    • Pumped in-line during polyol preparation
    • Metered to high-shear batch reactors with real-time viscosity monitoring
    • Introduced prior to final exothermic expansion

    Final product types

    • Flexible PU furniture foams
    • Automotive seat cushions
    • Rigid PU insulation panels and appliance cores

    5. Fine Chemical Intermediate for Agrochemical Synthesis

    Agrochemical production plants employ 1-Diethylamino-4-aminopentane as a specialized building block during the elaboration of certain pest control actives and plant growth regulator compounds. The amine functionality facilitates precise condensation and ring formation steps in multi-stage organic synthesis under validated hazard-control conditions. Process streams undergo exhaustive purity analysis and compliance checks with agricultural chemical registration guidelines.

    Industry compliance standards

    • FAO/WHO Joint Meeting on Pesticide Specifications (JMPS)
    • Directive 91/414/EEC (EU Plant Protection Products)
    • ISO 17025 analytical QC certification
    • Chinese Ministry of Agriculture (MOA) Product Registration Standards

    Typical usage ratio

    • 0.8–2.0% on batch mass; depend on synthesis yield and reaction pathway

    Downstream process integration

    • Added in-line during catalytic condensation steps in jacketed glass-lined vessels
    • Fed under strict nitrogen blanketing to prevent decomposition
    • Integrated with continuous analytical monitoring for target purity

    Final product types

    • Active agrochemical ingredients for insecticides and herbicides
    • Intermediate compounds for plant growth formulations
    • Precursor blends for controlled-release agrochemical granules
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    Certification & Compliance
    More Introduction

    1-Diethylamino-4-Aminopentane: A Critical Ingredient for Modern Synthesis

    Our Journey with 1-Diethylamino-4-Aminopentane

    Producing 1-Diethylamino-4-Aminopentane has shown us what matters most in specialty chemical manufacturing. Developing a stable, high-purity, and reliable supply demands patience, strict quality control, and tight process oversight. Since we began synthesizing this compound, feedback from our partners and lab technicians has shaped how we run every batch, from raw material handling all the way through purification, distillation, and packaging.

    Our product, with the most-recognized chemical structure featuring a primary amine group at one end and a diethylamino substituent on the other, demonstrates just how subtle changes in a molecule can create distinct advantages in real-world applications. For us, being the company that physically weighs, distills, analyzes, and ships each drum or bottle, means we see first-hand what impurities do to performance and what changes customers truly notice.

    Purity, Consistency, and Reliable Performance

    1-Diethylamino-4-Aminopentane (frequently called DEAPAN in certain industries) enters the stage as an intermediate bridging organic and specialty chemical sectors. Our biggest takeaway in more than a decade of production: inconsistent lots cause reaction failures down the stream. For end users, an off-color, off-odor sample usually means abandoned runs, scrapped material, or off-spec finished product. Every batch from our reactors is subject to gas chromatography and NMR observation to confirm specification. Each lot routinely tests at or above 99% purity by area, and we keep water content and residual organic acids below thresholds that can trigger unwanted side reactions.

    The molecule’s dual amine structure provides substantial reactivity and selectivity in forming bonds. Customers appreciate that our 1-Diethylamino-4-Aminopentane transitions easily from laboratory-scale research to pilot and full-scale synthesis without surprising shifts in behavior or yield. The product’s physical state—a clear, colorless to pale yellow liquid—makes it easy to handle and dispense. Uncomplicated sampling lets researchers work without extra steps, while tight purity means downstream chemistry proceeds as planned.

    Differentiation: Not All Aminopentanes Behave Alike

    Over years of manufacturing, we have run control syntheses using similar aminoalkanes including 1,4-Diaminopentane, 1-Piperidinopentane, and Diisopropylamino homologues. Our bench chemists quickly discover that even minor variations in the amine pattern impact not only reactivity but also physical handling, thermal stability, and even odor signature in finished products. Where 1-Diethylamino-4-Aminopentane excels is in balancing nucleophilicity with steric bulk; this offers advantages in selectivity when forming carbon-nitrogen bonds in both pharmaceutical and polymer applications.

    Comparing to simpler analogs like 1,4-Diaminopentane, users find our compound introduces less risk of crosslinking and side-reaction, which matters greatly for scale-ups in pharmaceutical intermediates. The diethylamino substituent not only boosts solubility in organic media but often prevents hydrogen bonding that otherwise gums up equipment. Practical chemists seeking versatile chain extenders, adduct formers, or building blocks for surface-active agents typically ask for repeated shipments after their first test batch, as they notice far lower clean-up time and better control.

    Meeting Modern Industrial Challenges with 1-Diethylamino-4-Aminopentane

    Every plant operator, pilot plant chemist, or formulation specialist faces new pressures, whether regulatory, cost-driven, or technical. Our experience has shown us how a single molecule’s source and quality can mean the difference between regulatory compliance or a costly recall. Traceability and documentation build trust; we back every lot with measured analytic data, including impurity profiles and detailed trace analysis. When customers face batch-tracking audits or extensive registration demands in pharmaceutical or agrochemical arenas, our records let them move forward without hesitation.

    Handling bulk volumes of an amine product with both secondary and primary groups brings challenges in shipping regulations and safe storage. We learned early that antistatic additives, low-moisture packaging, and robust container selection decrease the risk of oxidation or moisture ingress. Over time, our team’s careful selection of lining materials and closure methods minimized both contamination and evaporative loss. Storage in climate-controlled spaces preserves activity, something smaller repackers rarely promise.

    Applications That Benefit From Integrity

    Our product walks into many doors as a core building block for synthesis of specialty polymers, resins, and pharmaceutical intermediates. For many of these customers, getting an amine source that behaves predictably matters more than any other specification. The extra molecular bulk of the diethylamino group allows for custom-tailored pharmacophores when exploring novel CNS-active or cardiovascular agents. On the industrial side, our DEAPAN finds use as both a chain modifier and stabilization agent in epoxy resin and polyurethane systems. The chemical’s strong basic character, combined with its limited volatility at typical process temperatures, lets plant operators work continuously rather than battling with evaporative losses, reactivity swings, or changing viscosities.

    Clients in the agrochemical sector rely on our material for synthesis of urea and amide-based crop protection ingredients. Here, avoiding minor impurities that act as plant antagonists matters. Our strict control of key contaminant classes—especially aldehydes and residual solvents—means that even large-acreage applications proceed without measurable phytotoxicity. Direct feedback from the field led us to refine our drying and final filtration steps to ensure compatibility with the most sensitive crop delivery systems.

    Why Analytical Rigor Makes a Difference

    Years spent supporting customer audits taught us to document and share process analytics in real time. Modern users, whether in a regulatory-pressured pharmaceutical firm or high-throughput polymer plant, do not want guesswork. With each batch, we provide certified results of chromatographic analysis, including not just a single-point purity figure but full impurity breakdowns. For customers scaling up from gram to ton quantities, these records provide the confidence to commit resources and avoid late-stage surprises.

    Organoleptic inspection, such as clarity and odor, still matter on a day-to-day basis. Our on-site teams note that any deviation from the target appearance usually signals a shipping or storage breach. Tight container closure methods and atmospheric controls mean a customer’s sample on arrival matches what left our plant, not just on paper, but physically in-hand. Over time, rapid user feedback about subtle changes in color or scent prompted practical adjustments in stabilization and filtration steps, in ways that a third-party trader might never know to try.

    Serving Innovators and Traditional Producers Alike

    Whether our customer is a research group looking for a platform molecule for CNS drug discovery, or an industrial resin plant seeking to adapt to new regulatory rules, we respond to ever-changing needs using experience built on real production data. Some specialty chemical houses adopt a one-size-fits-all approach to amines; our team, as both manufacturer and hands-on problem solver, often goes back to the synthesis route to optimize yield or purity based on end-use discussions.

    When carrying out multi-step syntheses, process chemists in R&D appreciate our willingness to share full reactive impurity maps, right down to detection limits. Industrial customers who once faced foaming or color instability found that our improved purification steps—introduced based not on market research, but real-world plant-side discussions—solved headaches in a way off-the-shelf material never could. For our own process team, this interactive feedback loop means every bottle shipped has a chain of accountability and support unavailable when using a generic commodity supplier.

    Environmental and Regulatory Considerations

    Today’s standards require every chemical manufacturing decision to account for environmental impact and compliance with expanding safety guidelines. Our synthesis route for 1-Diethylamino-4-Aminopentane uses reagents and solvents chosen with recyclability and end-of-life concerns at the forefront. By minimizing hazardous byproducts and recycling process streams where feasible, we reduce both waste footprint and costs, savings which we pass along in pricing rather than marketing.

    Packaging reflects modern realities: resistant to UV, moisture, and oxidation, and meeting the highest international transit standards. Hazard labeling and documentation follow GHS and REACH guidelines, with batch-based SDS and CoA data accessible for global users. Our compliance team stays in close communication with regulatory bodies to anticipate emerging restrictions and update safety protocols promptly, ensuring uninterrupted supply chains to customers in Europe, the Americas, and Asia.

    The Value of Direct Relationship Between Manufacturer and User

    Working face to face with formulators and researchers, we witness creative approaches to harnessing the features of 1-Diethylamino-4-Aminopentane. Unlike distributors who can only relay specs from an upstream producer, direct makers are in a position to act on feedback. When one pharmaceutical pilot plant flagged a subtle byproduct below USP limits, we traced the root to a single process variable and reengineered a portion of the work-up, improving outcomes across multiple lots and helping the customer pass tough agency inspections.

    In another case, a resin producer dealing with batch-to-batch reactivity swings found that micro-traces of a specific propylamine contaminant, undetectable at routine screening levels, altered curing dynamics. Deep analytics and willingness to provide process notes allowed their R&D to adapt quickly. These on-the-ground experiences underscore the real-world importance of tight integration between production floor, laboratory, and end user—not just to maintain quality, but to evolve the product as customers’ needs change.

    Beyond the Bottle: Supporting Technical R&D and Scale-Up

    Supplying 1-Diethylamino-4-Aminopentane requires more than turning valves and running QA checks. Many of our industrial clients move from bench screening to pilot batches in the span of a few weeks. By consulting directly on process design, impurity removal, and scale-up obstacles, we help avoid common pitfalls: solvent compatibility, filtration blockages, unexpected physical changes at larger volumes, or off-odors from slow oxidation. Our plant’s hands-on staff tests not just chemical compatibility, but long-term stability under actual use conditions.

    We refine our process in collaboration with users. Over years, small tweaks in drying temperature, distillation pressure, and stabilizer choice have improved shelf-life and shipping stability. These changes stem from real feedback—when a user in a humid coastal climate described unusual turbidity, our technical team simulated those storage conditions, discovered the interaction causing the problem, and improved packaging accordingly.

    Because chemistry in the real world often deviates from textbook predictions, our technical team speaks plain language—translating not just chromatograms and NMR spectra, but their impact on downstream steps. It is not uncommon for a resin customer to phone in with a challenge that leads to testing a new reaction quenching step or alternate solvent at our pilot facility. These shared lessons build value on both sides, and strengthen the process chain from raw material through finished goods.

    Key Lessons from Decades in Manufacturing

    Our experience makes clear the trade-offs between process efficiency, product quality, and customer needs. By running our own reactors and purification rigs, we see how shifts in feedstock purity, process speed, or finishing steps echo through product quality and cost. Maintaining best practices and continually investigating process improvements yields not just better chemistry, but fewer operational headaches for users further down the value chain.

    Having supplied 1-Diethylamino-4-Aminopentane for years, we have supported users through supply chain shocks, regulatory updates, and fast-evolving technical goals. We take pride in getting the details right—the ones that matter most: color, clarity, odor, reactivity, and actual field performance. As makers, we are accountable for every drop delivered.

    Future Perspectives: Supporting Innovation and Reliability

    Looking ahead, we expect further emphasis on product traceability and sustainable manufacture. By investing in automated analytics and real-time batch monitoring, we reduce error rates and free up chemist time for innovation. The next wave of applications for 1-Diethylamino-4-Aminopentane is likely to demand even tighter impurity profiles, tailored for advanced materials and bioactive molecule synthesis. We remain committed to adapting our process controls, synthetic methods, and customer support to meet the demands of tomorrow’s science and industry.

    Making this product has shown us that chemistry is both science and craft, driven by respect for research, careful process work, and open communication. Whether a customer’s needs sit in a pharmaceutical laboratory or the engine room of a large-scale polymer plant, direct manufacturing insight and steady partnerships offer the surest route to success with specialty amine products.