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1,5-Dichloropentane

    • Product Name 1,5-Dichloropentane
    • Alias pentamethylene chloride
    • Einecs 203-927-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    306858

    CAS_Number 111-44-4
    Molecular_Formula C5H10Cl2
    Molar_Mass 141.04 g/mol
    Appearance Colorless to pale yellow liquid
    Odor Sweet, chloroform-like
    Boiling_Point 178-180 °C
    Melting_Point -42 °C
    Density 1.10 g/cm³ at 20 °C
    Refractive_Index 1.449 at 20 °C
    Flash_Point 69 °C (closed cup)
    Solubility_in_Water Insoluble
    Vapor_Pressure 2.2 mmHg at 25 °C

    As an accredited 1,5-Dichloropentane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500 mL amber glass bottle with a screw cap, labeled “1,5-Dichloropentane,” displaying safety pictograms, batch number, and CAS.
    Shipping 1,5-Dichloropentane should be shipped in tightly sealed containers, protected from light, heat, and incompatible substances. It must be labeled as a hazardous material (UN 1993, flammable liquid, n.o.s.). Transport in compliance with local, national, and international regulations, using approved packaging to prevent leaks and spills. Handle with appropriate PPE.
    Storage **1,5-Dichloropentane** should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from heat, sparks, open flames, and incompatible substances such as strong oxidizing agents. Keep the container away from direct sunlight and sources of ignition. Ensure appropriate chemical labeling and use secondary containment to prevent leaks or spills.
    Application of 1,5-Dichloropentane

    Applications of 1,5-Dichloropentane in Industrial Manufacturing

    1,5-Dichloropentane is a key specialty intermediate widely adopted in the synthesis of value-added chemicals across select industrial fields. The following application scenarios reflect the material’s actual integration points, addressing industry-specific requirements for compliance, formulation, production, and downstream finished goods.

    1. Synthesis of Ciprofibrate and Other Fibrate Pharmaceuticals

    Downstream pharmaceutical manufacturers select 1,5-dichloropentane as a controlled alkylating agent for producing ciprofibrate intermediates and other related drugs. Its dihalide structure positions it for direct utility in molecule elongation steps within active pharmaceutical ingredient (API) manufacturing. Extensive material traceability and process validation ensure end-product purity meets international medicinal use protocols.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • United States Pharmacopeia (USP) monographs for finished APIs
    • European Pharmacopoeia (Ph.Eur.) quality specifications
    • 21 CFR Part 211 – FDA Current Good Manufacturing Practice for Drugs

    Typical usage ratio

    • Typically 0.9–1.2 mol equivalents relative to key condensation substrates; adjusted for process yield optimization and regulatory impurity controls.

    Downstream process integration

    • Charged during the alkylation stage for the bifunctional modification of phenoxy acid intermediates in multi-step syntheses.
    • Introduced post-purification for final API formation or for subsequent transformation in side-chain modification steps.

    Final product types

    • Ciprofibrate API (hyperlipidemia treatment)
    • Fibrate-class lipid-lowering pharmaceuticals
    • Registered finished drug forms: tablets, capsules

    2. Production of Long-Chain Polyamines for Epoxy Curing Agents

    Epoxy resin system manufacturers utilize 1,5-dichloropentane as a versatile precursor to produce long-chain aliphatic polyamines used as coreactants. These polyamines enable controlled crosslinking density and heat resistance for industrial coatings and adhesives. Strict quality and environmental protocols regulate every batch throughout batch or continuous polycondensation processes.

    Industry compliance standards

    • ISO 9001:2015 Quality Management System
    • REACH Regulation (EC) No 1907/2006 – chemical safety requirements for supplied polyamines
    • EN 13980 – requirements for epoxy system ingredients in civil coatings
    • RoHS Directive (2011/65/EU) for electrical/electronic adhesive systems

    Typical usage ratio

    • Often 15–28% by weight as a dialkylation agent in polyamine chain extension; proportional to targeted molecular weight and desired viscosity.

    Downstream process integration

    • Added at initiation of amination or polycondensation with diamines under controlled temperature and pressure, minimizing side reaction byproducts.
    • Subjected to distillation and solvent removal stages to achieve high-purity polyamine curing agents.

    Final product types

    • Long-chain aliphatic polyamines for epoxy curing
    • Two-component industrial epoxy adhesives
    • Protective and anticorrosive epoxy coatings
    • Electrical casting resins

    3. Manufacture of Quaternary Ammonium Salts for Phase Transfer Catalysts

    Chemical process plants employ 1,5-dichloropentane to synthesize specialized quaternary ammonium salts that function as phase transfer catalysts (PTCs). Its five-carbon dihalo structure provides a customizable scaffold for preparing Cationic surfactants used in multiphasic organic reactions, especially in pharmaceutical and agrochemical synthesis. Extensive documentation and traceability support import-export controls and process audits.

    Industry compliance standards

    • ISO 14001 Environmental Management Systems for chemical manufacturing
    • REACH preregistration and substance notification (if supplied to EU customers)
    • OECD Good Laboratory Practice for substance analysis
    • Responsible Care Management System for hazardous intermediates

    Typical usage ratio

    • Standardly 1:1 molar ratio with amines to obtain mono- or bis-quaternary ammonium salts; adjusted per the alkylation degree and downstream purity specifications.

    Downstream process integration

    • Fed in controlled increments during the amination and quaternization stage.
    • Reaction mixtures undergo aqueous work-up and crystallization to isolate high-purity catalyst products.

    Final product types

    • Bis-quaternary ammonium salts (e.g., pentamethonium derivatives)
    • Phase transfer catalysts for industrial organic synthesis
    • Ion-exchange materials

    4. Creation of Cyclic Aliphatic Compounds for Specialty Monomers

    Advanced polymer producers integrate 1,5-dichloropentane as a starting material to cyclize and form cyclopentane- or piperidine-based monomers, which support development of high-performance polymers with tailored thermal and mechanical properties. Individual process parameters and stringent monomer quality controls ensure material compatibility for electronic and specialty engineering plastics markets.

    Industry compliance standards

    • ASTM D5630 for polymer additive purity determination
    • ISO 9001 Quality Management
    • RoHS and REACH for restricted substance content in plastic additives
    • UL 94 flame retardancy standards (for polymers)

    Typical usage ratio

    • Ranges from 10–22% by weight of the initial reaction charge, depending on targeted ring closure yields and subsequent monomer structure complexity.

    Downstream process integration

    • Introduced as the primary dihalide during intramolecular cyclization reactions under catalyzed conditions.
    • Subsequent purification yields the cyclic intermediates for copolymerization or further functionalization.

    Final product types

    • Cyclic aliphatic monomers (e.g., N-substituted piperidines)
    • High-temperature resistant specialty polymers
    • Engineering plastic grades for automotive and electronics
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    Certification & Compliance
    More Introduction

    Introducing 1,5-Dichloropentane from a Manufacturer’s Point of View

    Production Rooted in Experience

    In the chemical manufacturing world, experience grounds every process — from the first step of synthesis to filling the drum. Our teams have spent decades refining the synthesis of specialty chlorinated hydrocarbons, and 1,5-Dichloropentane has always demanded careful attention to detail. The product goes through several stages of distillation, purification, and stringent quality checks. Many laboratories and production plants have found that slight shifts in reaction temperatures or impurity profiles during synthesis can have dramatic effects on the downstream performance of this product. Drawing on extensive bench chemistry and full-scale production experience, we consistently meet the purity levels that specialty users expect.

    About 1,5-Dichloropentane

    1,5-Dichloropentane offers a unique backbone structure with chlorines placed on each end of a five-carbon chain. That arrangement enables the molecule to act as an impressive building block for more complex chemical syntheses. The two terminal chlorines frequently lend themselves to selective substitution, making it popular among customers developing specialty surfactants, reactive intermediates, and custom polymers.

    On our lines, batches come out as a clear liquid, ranging in purity from around 98% up to reagent grades. We routinely test for trace byproducts, including both higher and lower molecular weight chlorinated alkanes, since even minuscule contamination can interfere with downstream conversions or throw off analytical readings. These checks became standard years ago as low-level contamination led to unpredictable crashes in customer reactions. Troubles like fouling or inhibition often trace back upstream, so our QC group never lets a shipment out without fully documented GC and titration reports.

    Model and Consistency

    The most requested version matches the analytical monograph for industrial 1,5-Dichloropentane — a compound with a precise boiling point, narrow refractive index, specific gravity within tight bounds, and a defined colorimetric profile. Consistency here isn’t just about meeting numbers on a sheet. If we deliver the same batch to two R&D labs on different continents, both should land the same reaction yields and side-product profiles. Over the years, we’ve optimized column packing, distillation rates, and takeoff points based on what actually causes product variances, and it’s not always what textbooks predict. Engineers watch the entire operation around the clock, and we review every batch certificate before it ever leaves our gates.

    Applications: How the Product Proves Itself

    Few customers buy 1,5-Dichloropentane as an end in itself. Most value it for its role in multi-step syntheses, especially when building specialty surfactants, polymers, or coupling agents where twin chlorines on a flexible chain give unique properties. For years, manufacturers of quaternary ammonium salts and amine-alkylated resins have relied on our batches to give predictable conversions, reduced unwanted byproducts, and longer shelf-life to finished goods.

    The molecule sees use in alkylation reactions where the symmetrical arrangement is favored by research chemists tailoring bespoke surfactants or intermediates. Several of our pharmaceutical clients use it as a linker in active molecule assembly, where a stable, reproducible supply chain means they avoid regulatory delays during validation runs. In polymer chemistry, its bifunctional nature grants customizability for those manufacturing block copolymers, expanding the range of mechanical and chemical properties in finished plastics.

    Comparisons with Other Dichlorinated Alkanes

    For buyers new to dichlorinated pentanes, the distinction between 1,5- and other isomers such as 1,2- and 1,4-dichloropentane sometimes confuses procurement and technical teams. Structure makes all the difference: 1,5- keeps the chlorines at opposite ends of the chain, producing an entirely different reactivity profile from, say, 1,2-dichloropentane, where both halogens neighbor each other. In the lab, these differences show up quickly.

    We’ve seen downstream reactions fail to proceed or yield unwanted side products if substitutions are made among isomers, since placement of the chlorine affects everything from substitution rates to steric hindrance and overall chain length flexibility. For polymer applications, the uniform spacing in 1,5-dichloropentane often yields linear structures with distinctive rheological (flow) properties that the other isomers can’t match. Over time, research teams return to the 1,5- isomer when they need that symmetry or seek to avoid cross-linked or branched byproducts in their final materials.

    Handling and Practical Lessons from the Shop Floor

    Safe handling and reliable delivery always matter. Operators on our floor know the characteristic odor and volatility, taking steps that keep the workplace below occupational exposure limits while reducing cross-contamination between chloride streams. Years ago, our QA team worked alongside safety officers to develop handling practices based on real-world incidents, rather than just relying on the literature. Proper ventilation and individualized protective equipment remain non-negotiable.

    Seasoned technicians have learned to inspect fittings and storage tanks frequently, recognizing 1,5-Dichloropentane can react over time with certain gasket materials or improper seals if exposed for prolonged periods. Our logistics group ensures that all bulk transport complies with regional and international standards, and tanks or drums go through cleanliness verification between fills to minimize the risk of carryover or contamination.

    Correcting Misconceptions: What Really Matters in Sourcing

    Outsiders sometimes imagine that chlorinated alkanes are all interchangeable or that cut corners in purification won’t matter at scale. Our long experience tells a different story. Developing and making 1,5-dichloropentane at production scale involves attention to purity thresholds other suppliers overlook. Impurities might pass casual inspection, but they can derail processes later — causing yield loss, unexpected color in finished materials, or worse, reactivity problems during scale-up. The cash and labor saved by skipping purification steps rarely compensate for the lost productivity and reputational risk when something goes wrong downstream.

    We support teams during scale-ups or switchovers. Our R&D technicians work directly with customer chemists, reviewing NMR, GC, and product performance results to make sure there’s no mismatch between lab and plant. Years of troubleshooting have shown that many lab mishaps trace directly back to off-spec dichloropentane from inconsistent or low-grade suppliers — not to high theory or complicated kinetics as most believe.

    Pricing Truths and the Value of Transparency

    Price fluctuations on 1,5-dichloropentane come down to real-world factors: supply of raw chlorinated feedstocks, plant availability, and energy costs. We keep a close eye on market movements, but refuse to substitute materials or cut production steps purely for short-term gain. Many buyers search for the lowest cost per kilogram, only to find that hidden costs come back in process interruptions, contaminated intermediates, or stricter downstream cleaning requirements.

    We’re upfront about costs and batch histories. Every shipment includes a detailed certificate of analysis — not just a compliance statement, but an audited, lot-traceable record with real purity numbers, test results, and histories of each analytic event. Many of our buyers have discovered problems after buying cheaper material elsewhere, and they return to us seeking the documentation and batch consistency we treat as standard practice.

    The Future of 1,5-Dichloropentane Applications

    Emerging research trends suggest even broader horizons for dichlorinated intermediates. Increasing interest in green chemistry and novel materials pushes companies to refine their production routes, requiring even tighter controls over halogen placement and purity. From our vantage point, continuous process improvement — including mild reaction conditions and minimized waste — has become more than a value-add, it’s a necessity.

    Some research groups have begun exploring anchor points for further functionalization of the pentane chain. We’re in long-term partnerships with innovators testing our product in developing next-generation ionic liquids, specialized coatings, and performance additives for plastics. Years of feedback tell us that being responsive — delivering the exact batch parameters that new synthetic routes require, documenting trace impurities down to ppm, and producing in a timely, reproducible fashion — lies at the core of helping R&D teams succeed.

    In the face of regulatory changes, particularly those affecting chlorinated hydrocarbon handling across different jurisdictions, we invest heavily in compliance. Our approach means proactively studying changes in environmental guidelines and updating product stewardship protocols accordingly. The chemical industry’s landscape shifts with each new directive or customer-driven safety review, but hands-on experience has taught us that transparency and continuous adaptation bring lasting trust in supply partnerships.

    Best Practices in Collaboration and Customization

    Manufacturing 1,5-dichloropentane isn’t a one-size-fits-all operation. Sometimes a customer requests tailored impurity profiles or a blend with specific stabilizers. Our technical support responds based on hard-won experience: not every batch is created equal, and consistent scale-up from bench to reactor often demands process tweaks. We’ve worked through countless process adaptation cycles — swapping out condenser configurations, tuning run temperatures, or adjusting column parameters — to meet non-standard specifications.

    Support never stops at the loading bay. Teams stay available for troubleshooting even months after delivery, whether a customer faces an unexpected process change or a new regulatory hurdle. That willingness to share our manufacturing reality, test reports, and lessons from the plant ensures that problems get solved and projects move forward.

    Working Toward More Sustainable Practices

    Environmental responsibility forms an everyday reality, not just a slogan tacked to company walls. The industry faces steady pressure to reduce waste, minimize emissions, and move toward closed-loop manufacturing. Over time, we’ve implemented solvent recovery, updated emission control systems, and developed recycling programs for chlorinated byproducts. These don’t just shrink waste — they deliver cost savings and allow us to offer competitive pricing without sacrificing quality.

    Years of feedback from both regulators and customers have forced innovation. As new purification technologies and raw material sources become available, our engineering teams weigh both the costs and real-world results. What looks perfect on paper rarely delivers in the plant until subjected to actual production stress and regular audits. It’s hands-on learning that keeps our operations resilient and customer partners confident.

    Closing Thoughts from the Plant Floor

    Daily operations remind us that small details in handling, sourcing, and consistency matter most. Experienced operators, vigilant quality control, and ongoing customer dialogue drive the reliability clients look for. Supply chain disruptions, regulatory pressure, and market swings can all influence how the product gets made and delivered, but focusing on practical experience every step of the way assures dependable performance.

    1,5-Dichloropentane’s value comes not just from its formula or price point, but from the manufacturing principles and transparency that support it. The end-users — chemists, process engineers, research groups, and production managers — all rely on a supply partner ready to back up claims with real data and real-world support. Decades of industry experience have shaped our approach, and it’s those hard-earned lessons that enable us to deliver to both established and emerging markets worldwide.