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1,2-Ethylenediamine

    • Product Name 1,2-Ethylenediamine
    • Alias Ethylenediamine
    • Einecs 203-468-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    439485

    Chemical Name 1,2-Ethylenediamine
    Formula C2H8N2
    Molar Mass 60.10 g/mol
    Cas Number 107-15-3
    Appearance Colorless liquid
    Odor Ammonia-like
    Melting Point 8.5 °C
    Boiling Point 116-118 °C
    Density 0.899 g/cm3 (20°C)
    Solubility In Water Miscible
    Pka1 6.89
    Pka2 9.93

    As an accredited 1,2-Ethylenediamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1,2-Ethylenediamine is typically packaged in a 1-liter amber glass bottle with a secure screw cap and hazard labeling.
    Shipping **1,2-Ethylenediamine** should be shipped in tightly sealed containers, stored in a cool, dry, and well-ventilated area. It is classified as a hazardous material and must be transported according to relevant regulations (such as DOT, IATA, or IMDG). Proper labeling and documentation are required, and personal protective equipment should be used during handling.
    Storage 1,2-Ethylenediamine should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from heat, sparks, and open flames. Keep it separate from acids, oxidizing agents, and moisture. Use corrosion-resistant storage materials. Store away from incompatible substances, and ensure proper labeling. Protect from physical damage and access by unauthorized persons.
    Application of 1,2-Ethylenediamine

    Applications of 1,2-Ethylenediamine in Industrial Manufacturing

    As a direct manufacturer with decades of experience supplying high-purity 1,2-ethylenediamine to industrial customers, we focus on value-added downstream applications where this diamine plays an integral and irreplaceable role. Below we highlight real-world manufacturing scenarios with application-specific compliance standards, recommended inclusion levels, process integration, and corresponding end-use products. Our technical team supports customers globally in meeting precise requirements for each unique sector.

    1. Epoxy Curing Agents for Industrial Coatings and Composites

    In epoxy resin systems, 1,2-ethylenediamine acts as a reactive curing agent, promoting rapid crosslinking for high-performance coatings and composite components. Formulators adjust ingredient ratios based on target pot life, gel time, and mechanical strength requirements for heavy-duty protective finishes, floorings, and advanced composites. We provide technical support covering the entire chain from resin admixing to QC testing of the final product.

    Industry compliance standards

    • ASTM D5895 (Standard Test Methods for Evaluating Curing Properties of Thermosetting Coatings)
    • ISO 8130 (Powder Coatings – General Test Methods)
    • REACH Regulation (EC 1907/2006, Annex XVII restrictions for workplace safety)
    • EU Directive 2004/42/EC (VOC limitations for coatings)

    Typical usage ratio

    • Commonly 2-8 phr (parts per hundred parts resin); adjust based on resin type, targeted cure speed, and application thickness.

    Downstream process integration

    • Introduced during the epoxy resin blending stage, with careful temperature and mixing controls to ensure uniform dispersion and reactivity.

    Final product types

    • Heavy-duty industrial floor coatings, corrosion-resistant tank linings, tooling composites, and structural adhesives.

    2. Chelating Agent Manufacturing for Water Treatment Chemicals

    1,2-Ethylenediamine serves as a key intermediate in the synthesis of chelating agents, providing nitrogen-donor sites essential for complexes like EDTA. Major water treatment formulation plants use this raw material to produce high-purity chelators that enhance metal ion control in potable water, industrial process streams, and municipal wastewater systems. Consistent quality and traceability are required at every batch step.

    Industry compliance standards

    • EN 120 (Chemical used for treatment of water intended for human consumption)
    • NSF/ANSI Standard 60 (Drinking Water Treatment Chemicals – Health Effects)
    • ISO 9001:2015 (Quality management for chemical manufacturing)
    • REACH Annex XVII (Chemical restrictions)

    Typical usage ratio

    • Feed ratio depends on target chelator type: for EDTA synthesis, 1,2-ethylenediamine is typically charged at a stoichiometric 1:2 mass ratio with monochloroacetic acid; minor variations accommodate plant-scale and yield optimization.

    Downstream process integration

    • Fed into high-temperature alkylation reactors as a core diamine building block at the initial chelator synthesis stage, followed by purification and formulation.

    Final product types

    • EDTA tetrasodium, EDTA disodium, biodegradable aminopolycarboxylate-based chelators, mixed chelator blends for municipal and industrial water conditioning.

    3. Intermediate for Pharmaceutical API Synthesis

    GMP-compliant pharmaceutical plants use 1,2-ethylenediamine as a core building block in the manufacture of select active pharmaceutical ingredients. It is involved in the synthesis of antibacterial, antiviral, and anti-tuberculosis medications where high purity and trace-level impurity control are critical. Our production process ensures ultra-low heavy metals, consistent moisture, and certified batch traceability to meet the regulatory requirements of international API markets.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice Guide for Active Pharmaceutical Ingredients)
    • European Pharmacopoeia (Ph. Eur.) specifications for process intermediates
    • US FDA 21 CFR Part 210/211 (Current Good Manufacturing Practice in Manufacturing, Processing, Packing, or Holding of Drugs)
    • China NMPA (Drug Master Files for chemical intermediates and APIs)

    Typical usage ratio

    • Calculated based on the targeted molecular yield during stepwise API building block condensation; small-scale examples use mole-mole basis with downstream step adjustment for purity, ranging from 1:1 to 1:2 with coupling reagents.

    Downstream process integration

    • Reacted during the early or intermediate synthetic stage, followed by purification, salt formation, or protective group addition according to the specific pathway for the target API.

    Final product types

    • Pharmaceutical actives such as ethambutol, hydroxyzine, and certain antiviral drug intermediates.

    4. Accelerator in Rubber Vulcanization

    Rubber compounding operations use 1,2-ethylenediamine as a secondary accelerator in sulfur vulcanization processes, particularly in the production of high-performance rubber goods. Its bifunctional amine structure modifies curing kinetics to improve flexibility and compression set in automotive, industrial, and oil-resistant elastomer formulations. Consistent granulation or liquid quality reduces formulation variability in batch or continuous kneader systems.

    Industry compliance standards

    • ISO 9001:2015 (Quality management systems for rubber compounding)
    • ASTM D3182 (Standard Practice for Rubber – Materials, Equipment, and Procedures for Mixing Standard Compounds)
    • RoHS 2011/65/EU (Restriction of hazardous substances, relevant for automotive and electronics elastomers)
    • REACH SVHC (if applicable for downstream use)

    Typical usage ratio

    • Typically added at 0.2-2.0 phr (parts per hundred rubber), with the precise amount adjusted according to rubber grade, sulfur content, and performance targets.

    Downstream process integration

    • Introduced during internal or open-mill mixing stages alongside other accelerators and crosslinking agents before molding and vulcanization.

    Final product types

    • Automotive weatherstripping, oil-resistant hoses, elastomeric seals, and industrial gaskets.

    5. Polyamide Engineering Plastic Synthesis

    Major engineering plastics producers employ 1,2-ethylenediamine as a chain extender and diamine component in condensation polymerization with adipic or sebacic acid to produce select polyamides. The ratio and introduction point of the material directly influence molecular weight and end-use mechanical properties, supporting the automotive, electronics, and performance industrial goods industries where dimensional stability and chemical resistance are demanded.

    Industry compliance standards

    • ISO 1874 (Plastics — Polyamides — General specifications for polyamide materials)
    • UL 94 (Safety of Flammability of Plastic Materials for Parts in Devices and Appliances)
    • QAS for food contact: EC 10/2011 (when used for food-contact PA materials)
    • Automotive OEM material standards (e.g., VW 50133 for polyamide components)

    Typical usage ratio

    • Charge ratio typically ranges from 0.8 to 1.2 mol per mol of dicarboxylic acid depending on desired chain length, polymer viscosity, and end application.

    Downstream process integration

    • Introduced into the polycondensation reactor at the initial monomer charging stage under high-temperature, inert atmosphere conditions, followed by extrusion and pelletizing.

    Final product types

    • Nylon-2, Nylon-2,10, specialty polyamide copolymer pellets for automotive engine covers, cable ties, and industrial pump housing materials.
    Free Quote

    Competitive 1,2-Ethylenediamine prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Introducing 1,2-Ethylenediamine: Experience from the Manufacturer’s Bench

    Over years of hands-on work inside our own manufacturing halls, 1,2-Ethylenediamine has proven to be one of the most versatile and dependable molecules for several key industries. Sitting at the core of our production stream, this diamine—recognized by its sharp, ammonia-like odor and unmistakable reactivity—finds its way into everything from chemical synthesis to water treatment, pharmaceuticals, adhesives, textiles, and agricultural chemicals.

    Our Ethylenediamine, Under the Microscope

    Standing in the plant, observing each reactor run, the difference between theoretical purity and what actually comes off the line is crystal clear. We produce 1,2-Ethylenediamine in large volumes with tight control on its purity, usually meeting or exceeding 99.5% by GC when supplied for most industrial uses. Color plays a role too. We keep a close eye on visual clarity—our process yields a water-white or very pale yellow liquid, free from suspended matter, and no visible contamination enters the product streams. Moisture is another critical concern. High water content starts trouble downstream for many users, particularly in polymer or pharmaceutical synthesis, so our batches stay below 0.2% water as measured by Karl Fischer titration.

    Once in storage, proper handling matters. We’ve worked through more than one case where an overlooked gasket allowed trace oxygen to sneak in, yellowing the product and raising the pH as peroxides formed—troubles easily avoided with welded stainless tanks, robust nitrogen blanketing, and solid discipline on drums and IBCs. Out the gate, specifications do matter, but no spec sheet ever tells the whole story about a product’s behavior in real industrial conditions. It’s the sort of knowledge that comes from years of both production and seeing where batches end up, whether in textile softener lines or amine curing agents.

    Practical Experience: Applications that Drive What We Make

    Decades as the original manufacturer give a different view of 1,2-Ethylenediamine’s value. This compound drives more chemistry than most outsiders expect. Its two primary amine groups make it a vital link in polymer chains, chelating agents, epoxy resin hardeners, corrosion inhibitors, and rubber vulcanization accelerators. U.S. and European markets often draw on our streams for the production of EDTA, itself indispensable in everything from water softening to food preservation. On the pharmaceutical side, certain antihistamines and local anesthetics depend on this diamine scaffold—missions that leave no room for off-odors, colored impurities, or trace chlorides.

    For those formulating fuel and lubricant additives, we’ve learned purity alone is not enough. Our line operators have dealt with complaints about off-ratio amines in previous years; even a slight deviation from tight molar excess leads to unpredictable blends in finished additives. The same goes for chelating agents, where minuscule levels of chloride or iron cause problems with product shelf life, performance, or stability. Those lessons drive why our process engineers monitor trace metals with atomic absorption and iron (III) content well below 1 ppm in premium grades.

    Comparing Our Product: Details Matter More Than Claims

    Sitting through enough customer audits, it becomes obvious—”commodity” doesn’t mean “all suppliers are equal.” While other vendors may promise equivalent specifications for 1,2-Ethylenediamine, years in the business reveal nuances in viscosity, color stability, and low-odor profiles that end up making a difference far downstream. Degraded or colored material can foul reactors, create off-grade batches, or force customers into reworking production runs. We learned early that careful washing, dedicated distillation columns, and absolutely clean storage tanks guarantee a material that performs as intended.

    Some suppliers blend batches or market downgraded streams as technical grade; our customers grew frustrated with blend lines, stale odor, or problems during downstream distillation. Our production, based on dedicated lines, avoids trace contamination from previous products. These measures prevent mix-ups and give real consistency from drum to drum. That means fewer surprises for users processing hundreds of tons per year and fewer costly delays during plant operations. Consistency is earned, not written into existence.

    Distinct From Other Amines: What Actual Producers Notice

    The basic structure of 1,2-Ethylenediamine sets it apart from analogs like 1,3-propylenediamine or hexamethylenediamine. We spend time with chemists sorting out choices depending on reactivity, boiling point, and the effect of chain length or branching on the downstream polymer or complex. Our product has a boiling point close to 117°C, which means careful attention to heat tracing and venting in customer facilities; lower chain diamines call for different handling, and the evaporative loss or cross-over during storage looks nothing like the behavior of amines even a few carbons longer.

    Compared to monoethanolamine or diethylenetriamine, Ethylenediamine’s two closely-spaced primary amines lead to strong chelating ability and higher reactivity in many condensation and curing reactions. In our manufacturing environment, switching lines between these products requires full washout to prevent carryover; each amine finds its own market, and while they share a family name, they rarely substitute for each other without side effects in the final application. When customers mistakenly employ another diamine, conversion yields tank, product stability drops, and reactivity goes sideways; it’s the kind of risk that becomes apparent only through actual, not theoretical, experience.

    Real-World Handling Lessons

    Volume producers feel the weight of mishandling long after a spill. The pungent odor of 1,2-Ethylenediamine leaves no doubt if containment breaks, and we know small leaks rapidly escalate into corrosive hazards. With hundreds or thousands of drums moving each year, we keep training cycles tight so every operator recognizes proper PPE and knows exactly how to deal with a drum in distress. Spills and vapor exposures are both health and quality concerns—recontamination means lost lots, extra waste charges, and hours spent on remediation. Over the years, investing in hard-piped systems and secondary containment cut our incident rate to a fraction of what it was, making for a safer, cleaner environment and reliable supply to our customers without interruption.

    Anyone using this amine on a production scale immediately faces the challenge of ventilation. On a muggy summer day, production bays fill with vapor if airflow isn’t up to code. Early batches we made in under-ventilated lines left operators with watery eyes and headaches. Forced upgrades—bigger fans, higher extraction rates—now keep both ambient air and working conditions within safe limits. Consistent air monitoring prevents problems before they drift from nuisance to hazard. That’s not theory; it’s how seasoned plants avoid costly shutdowns and workplace claims.

    A Commitment Beyond the Drum

    Our relationship with 1,2-Ethylenediamine stretches from precursors to packed drums and beyond. We have worked through global supply chain swings—feedstock shortages, shipping delays, and changes in environmental policy—without cutting corners. When circling around compliance with ever-tougher safety and registration frameworks, we’ve modified procedures, updated labeling, and retooled reactor controls to ensure every litre shipped meets domestic and international benchmarks. Down the road, we field feedback, track near-misses, and tweak packaging based on real use data, not marketing reports. It’s a feedback loop that tightens standards and narrows the margin for error over years, not weeks.

    Customers with demanding requirements found in us a partner who gets the real difference between paper specs and delivered value. If a downstream processor calls us at 2:00 AM about trace fouling in a reactor, we pull samples, review logs from the relevant batch, and dig into root causes—often turning up hidden storage issues or genuine process improvement opportunities. That work produces actionable tweaks, not excuses or passing blame to third-party logistics.

    Supporting the Circular Economy

    Persistence pays off in waste reduction and improved lifecycle management. Early on, spent 1,2-Ethylenediamine streams simply became hazardous waste, but newer projects loop recovered amine back into manufactured output or supply it to outside recyclers. Today, a growing side business emerges from spent amine reclamation, lowering net purchase cost for users and shrinking environmental footprints. Achieving this closed-loop model took years of trial and error, but the benefit in reducing both raw consumption and disposal liability helps everyone up and down the chain. Regulations inch tighter on VOCs and hazardous organic emissions; real-world producers need to be both more inventive and more disciplined.

    Practical solvent recovery from contaminated amine mixtures is non-trivial. There’s no one-size-fits-all solution. We run custom distillation programs based on composition analysis for our customers needing circular solutions—offering tank rental for intermediate holding, technical support with demulsifiers, and plant trials for recycling. Not every batch is a candidate for return, but collectively the fraction that is has made a measurable dent in both overall raw material sourcing and long-term operating costs.

    Remaining at the Forefront of Safety and Stewardship

    1,2-Ethylenediamine’s reactivity is one of its greatest strengths, but it puts experienced producers on their toes. In many shops, replacement of older gasket material, upgrades from unlined carbon steel to stainless accessories, and stricter drum labeling policies became part of our routine schedule. Each upgrade responds not to paperwork, but to incidents seen on the ground—material degradation from hot summer storage, seal failures under pressure, or misdelivery with unmarked containers. We focus closely on staff competency, updated MSDS distribution, and prompt response to any customer query about handling or compatibility.

     

    Challenges and Solutions in a Changing Market

    As more customers ask for higher purity or specialty blends, we see the strain of legacy production lines optimized only for bulk output. Moving above a 99.5% purity for certain pharmaceutical or electronics uses required adding new distillation steps, modern online analyzers, and tighter nitrogen-blanketed transfer lines. Old habits and legacy equipment make way for real upgrades—not always glamorous, but necessary as market demand shifts, standards tighten, and application requirements evolve. The demand for greener chemistry also drives real operational changes. Several years ago, chlorinated feedstocks began to fall out of favor, forcing a switch to cleaner alternatives and increased catalyst recovery in upstream synthesis runs. These moves brought production up to new environmental standards and eliminated some of the less controllable about downstream contamination risks.

    We have pressed our teams on the ground for creative input, not just from chemists, but also maintenance techs and shift supervisors who see first-hand how process realities affect final product quality. Troubles with unplanned shutdowns, trace corrosion, or off-ratio blends tend to surface in daily operation meetings long before the lab ever catches them on QC paperwork. Solutions often come from those closest to equipment—improved filtration, modified storage, or procedural controls on cleaning cycles—incrementally raising the baseline and building up trust with longtime customers who value the reliability this brings.

    The Reason Behind Our Consistent Supply

    Reliability doesn’t come from simply filling drums. Each phase—feedstock procurement, synthesis, isolation, purification, packaging, shipment—is a checkpoint shaped by prior crises and hard-won process improvements. Decades of operating our own reactors teach us where cost-cutting invites quality slip and where tighter quality assurance returns real long-run savings.

    Tracing every drum back to the production date makes it simple to run root cause analysis if a question comes up about odd product trace or specification drift. We make our own corrections and constantly learn from outputs. When supply chain disruptions threatened global amine pricing, established back-channels for emergency sourcing made all the difference—enabling us to maintain steady shipments, even rolling out safety stock strategies with customers forecasting unpredictable spikes in demand.

    Testing and Documentation Practices: Built from Experience

    Real trust comes through transparency, not theoretical documentation. Every batch leaves with full analytical data—GC purity, water content, color index, metal and chloride traces where relevant—and historical data on request for bulk users or regulated industries. Certificates help, but it’s the practical experience our teams have with each lot that reveals the reliability behind those numbers. Tracking which units or tanks yielded any issues, we provide relevant users with actual remediation guidance, including deep-clean or batch cut-out recommendations, rather than one-size-fits-all platitudes.

    We invest in regular audits—internal and sometimes conducted with customer participation—to ensure both equipment and operator readiness. Each audit identifies not just compliance gaps, but improvement opportunities—a sustained process that raises the bar with each cycle. Our lab managers and operators proudly present actual runs for review, open to questions and inspection from outside, confident in both our process and our product.

    Future Directions: Meeting Evolving Market Needs

    The market landscape changes each year, driven by shifting regulatory mandates, emergence of new end-user industries—think lithium battery electrolytes, advanced composites, and more advanced chelates—and a growing call for both higher purity and environmentally sensitive production. We share our expertise through technical exchanges with longtime customers, never hoarding process insights or quietly tolerating problems that will only surface downstream. Each upgrade to our process—from improved temperature staged reactors, to new distillation trays, to more accurate dosing pumps—is made with the practical needs of formulators, synthesizers, and compounders in mind.

    By drawing directly from real cases in our plant—what worked, where we struggled, and how those lessons become operational improvements—we provide not just a specification sheet, but the experience-backed assurance that delivered product will meet users’ expectations where it counts. Partners coming to us for 1,2-Ethylenediamine quickly learn the value of supply chain transparency, real-world technical support, and a true manufacturer’s accountability for every shipment, not just the first.

    Those searching for mere lowest cost per kilo may find dozens of options on the global market. Long-term customers tell us the ability to rely on consistent, tight-spec diamine—delivered on schedule and with beneath-the-hood knowledge at every stage—makes the difference between a robust operation and a series of fire drills. We bring the focus of decades in practical, technology-driven manufacturing of 1,2-Ethylenediamine, aiming always for safer operations, cleaner output, and greater reliability for each customer needing this unique and powerful intermediate.