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HS Code |
121699 |
| Cas Number | 106-88-7 |
| Iupac Name | 1,2-Epoxybutane |
| Molecular Formula | C4H8O |
| Molar Mass | 72.11 g/mol |
| Appearance | Colorless liquid |
| Density | 0.861 g/cm3 at 20°C |
| Boiling Point | 63°C (145°F) |
| Melting Point | -111°C (-168°F) |
| Flash Point | -18°C (0°F) |
| Solubility In Water | Soluble |
| Vapor Pressure | 183 mmHg at 25°C |
As an accredited 1,2-Epoxybutane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1,2-Epoxybutane is supplied in a 500 mL amber glass bottle with a tightly sealed cap and hazard labeling. |
| Shipping | **1,2-Epoxybutane** should be shipped as a hazardous chemical according to UN1993 regulations for flammable liquids. Use appropriate, tightly sealed containers compatible with epoxides, and ensure clear labeling. Transport with proper documentation, in compliance with local and international regulations, and avoid exposure to heat, sparks, or open flames during transit. |
| Storage | 1,2-Epoxybutane should be stored in a cool, dry, well-ventilated area away from heat, sparks, flames, and direct sunlight. Keep the container tightly closed and away from incompatible materials such as strong acids, bases, and oxidizing agents. Ensure containers are labeled properly and protected from physical damage. Use approved containers, and keep away from sources of ignition, as it is flammable. |
Applications of 1,2-Epoxybutane in Industrial ManufacturingAs an established chemical raw material producer, we supply 1,2-epoxybutane to high-value downstream sectors where its unique structure delivers functional performance in specialty synthesis. Below, we outline the principal industrial applications, with detailed formulation approaches, industry compliance requirements, manufacturing integration, and representative end-products. 1. Synthesis of Pharmaceuticals IntermediatesPharmaceutical synthesis processes use 1,2-epoxybutane as a controlled epoxidation reactant, especially in the construction of key molecular scaffolds for active pharmaceutical ingredients (APIs). Its bifunctionality supports regioselective nucleophilic addition, which is essential in the development of diverse intermediates, such as beta-blockers, antihistamines, and local anesthetics. Precision in handling, purity control, and process optimization play a direct role in meeting global cGMP standards for medicinal use. Industry compliance standards
Typical usage ratio
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2. Manufacture of Fine Chemicals and Agrochemical IntermediatesChemical plants utilize 1,2-epoxybutane as a reactive building block for targeted syntheses in the fine chemicals sector, particularly for the creation of agrochemical reagents and precursors to active crop protection molecules. The material’s tailored reactivity enables stepwise functionalization, facilitating direct alkylation reactions which are instrumental for generating select insecticides, fungicides, and herbicide intermediates. End-user requirements for stability, activity, and environmental fate heavily influence the integration strategy on the production floor. Industry compliance standards
Typical usage ratio
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3. Production of Surfactant and Specialty Polymer PrecursorsThe surfactants and specialty polymers industries incorporate 1,2-epoxybutane into precision chain-extension or grafting processes, taking advantage of its epoxide group to introduce controlled branching or reactive functionality. This is particularly critical for manufacturing non-ionic surfactant head groups, compatibilizer resins for adhesives, and intermediates for waterborne polymer dispersions. Accurate dosing and temperature control prevent side reactions and ensure batch-to-batch consistency, supporting product reproducibility in high-throughput settings. Industry compliance standards
Typical usage ratio
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4. Additive in High-Performance Lubricant SynthesisSpecialty lubricant manufacturers explore the selective reactivity of 1,2-epoxybutane to prepare tailored additive packages and functionalized base stocks. Its controlled ring-opening behavior enables synthesis of molecules with fine-tuned polarity and oxidative stability, supporting the engineering of transmission fluids and process lubricants that meet stringent OEM lifecycle benchmarks. Dosing and blending precision directly influence viscosity index improvement and long-term anti-wear attributes. Industry compliance standards
Typical usage ratio
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Working in the field of chemical manufacturing, challenges rarely pause. Every process step impacts the next, every feedstock or reagent can set the tone for shifts running smoothly or setting production back. Out of the lengthy list of glycidyl ethers and epoxides available, experienced production teams turn again and again to 1,2-Epoxybutane. Called by some as butylene oxide, this clear, colorless liquid holds its own in a portfolio often crowded with similar molecules.
Time on the plant floor has shown the distinct qualities of 1,2-Epoxybutane. For our teams, clarity in physical behavior and performance means fewer complications during storage, transfer, and use. 1,2-Epoxybutane brings true versatility as an intermediate. Its molecular weight and boiling point cut down on the volatile handling issues that sometimes arise with epichlorohydrin or propylene oxide, yet the ring strain of the epoxide function still lends itself well to active chemistry.
Over the years, investing in purification systems has paid dividends. The model of 1,2-Epoxybutane that leaves our reactors typically offers purity grades from technical to high, suitable for both large-scale industrial conversions and high-demand applications where traces of byproduct or water can set off downstream fouling or cause catalyst decay. Customer requests focus as much on consistent batch-to-batch performance as on targeted impurity profiles, and this keeps our quality control lab busy analyzing every tank and drum.
Some facilities take advantage of our offering to customize batch sizes and shipping formats to fit unique handling or storage requirements, but no matter the configuration, our standard here never shifts. Tanks and lines measured and flushed according to script, reactors validated for cleanout, and raw materials certified for trace contaminants — it ends up in the finished product, in how reliably 1,2-Epoxybutane behaves at the end user’s site.
Plenty of our longtime customers run polyol plants, coating production, or perform surfactant synthesis. 1,2-Epoxybutane acts as a fundamental building block because its epoxide ring opens readily with both acids and bases, making it reactive enough for many organic transformations. Several major reactions use this epoxide as a source for creating butanediols, especially 1,2- and 1,4-butanediol variants, offering routes into plasticizers, polyurethanes, and resins. Chemists appreciate the selectivity in these transformations, saving troublesome byproduct purification steps that can drag out cycle times.
Anyone working on specialty surfactants knows how necessary it is to access compact, functionalized molecules that result in desirable hydrophilic-lipophilic balance. 1,2-Epoxybutane’s structure, balanced by its practical hydrophobic alkyl backbone and its strained epoxide group, gives formulators more room for fine-tuning properties, whether aiming for detergents or nonionic emulsifiers. We see its use spread into agrochemical adjuvants and textile auxiliaries, not only because of its chemistry, but because it processes well under both batch and continuous feed—our shop floor setup guarantees the reliability these partners count on.
Downstream plastics and rubber industries continue to draw from our larger lot sizes, taking in 1,2-Epoxybutane for chain-extension chemistry. Under controlled catalyst, the oxide ring opens and incorporates smoothly onto growing polymer chains. Where flexibility and impact resistance matter—like thermoplastic elastomers or rubbery blocks in copolymers—this small molecule often changes the product’s performance. Our technical teams hear plenty from production engineers who value a reagent that resists clogging, scales well, and stores steadily under appropriately managed conditions.
While propylene oxide or ethylene oxide may crop up as alternatives on paper, our hands-on experience reveals genuine differences with 1,2-Epoxybutane. Its moderate boiling point limits excessive evaporation during charge and dump cycles, a noticeable benefit in keeping our filling areas cleaner and our solvent recovery lines less overworked. This stability spares some of the headaches often found with higher volatility glycidyl ethers.
Compared to epichlorohydrin, 1,2-Epoxybutane does not introduce chlorinated residues that can later affect material compatibility or environmental downstream. Our customers in electronics and advanced coatings choose this option because there’s less concern about halogen contamination—a critical requirement for hundreds of highly sensitive end-uses. Biocidal or regulatory compliance favors butylene oxide when chlorinated byproducts are to be avoided, supporting a smoother workflow when it comes to waste stream handling as well.
Another factor often raised in our conversations with application chemists focuses on the nuanced reactivity of 1,2-Epoxybutane. Its four-carbon skeleton lends a unique blend of flexibility and chemical reactivity that’s not always present when using the smaller epoxides. Polyols and ethers achieved from this molecule differ in response to temperature, viscosity, and chemical resistance, giving R&D teams more opportunity to dial in desired properties. Our line technicians especially notice how reaction rates, heat generation, and solubility can be matched more closely to the downstream needs, saving energy and simplifying safety protocols.
Through thousands of hours spent planning, loading, and maintaining our equipment, safe and effective handling tips become nearly second nature. Storing 1,2-Epoxybutane requires tight control of temperature and exclusion of moisture, keeping it dry and segregated from acids and strong bases to avoid runaway reactions. We have insulated storage tanks and nitrogen blanketing—what matters most is keeping oxygen out, avoiding unwanted polymerization or slow degradation. Each loading crew member follows written process sheets that draw on hard-won experience, reducing the chance of incidents during transfer or sampling.
Cylinder and drum storage needs dedicated, ventilated areas, so that minor leaks or spills can be contained and recovered easily. Every year, we invest in training new staff and auditing our loading lines. Even small oversights—leaving a valve slightly open, or mislabeling a drum—carry too much risk for facilities housing highly reactive chemicals. Regular drills and close observations produce tight protocols, which benefit customers by ensuring their product reaches them untouched by environmental or cross-contamination.
Acute awareness of the chemical’s volatility and reactivity, honed over years of production and shipment, teaches teams to track batch numbers closely. This way, issues—rare as they are—can be traced and corrected without long downstream pauses. No one wants a surprise in the polymerization reactor because of an unnoticed contaminant or outdated batch, and our record keeping reflects that lesson.
Securing the raw material stream for 1,2-Epoxybutane remains a cornerstone of reliable production. We maintain multiple supply lines for primary feedstocks, drawing from both petrochemical and, when feasible, bio-based origins. Recognizing how downstream partners face increasing pressure for lower carbon footprints, our procurement group also explores sourcing from facilities closer to the consumption point, cutting both lead times and the impact of transport emissions.
Automation in our plant, mixed with skilled operator oversight, leads to higher yield and lower waste, which is no small feat when handling such a reactive material. Vigilant process improvement—whether tweaking reaction parameters or enhancing purification columns—translates to fewer unwanted byproducts. Less off-spec product means less costly and energy-heavy reprocessing. These operational choices support both profitability and our commitment to safer, cleaner chemical production.
New uses for 1,2-Epoxybutane emerge regularly, but so do regulatory and environmental expectations. Over the years, the demand for documentation, both for import/export and for local compliance, has intensified. As manufacturers, we devote considerable resources to building transparent paperwork trails, maintaining up-to-date certificates, and validating analytical protocols beyond minimum requirements.
Environmental scrutiny rises especially when handling any molecule with recognized toxicity. We keep emissions, spills, and unplanned releases tightly monitored, using both automated sensors and trained personnel. Our waste recovery units collect rinse streams and vented vapors, treating them on-site before release. Communities near our facilities watch us closely, and we welcome their questions—hard-won trust depends on showing stewardship, not just claiming compliance.
The industry often discusses replacement paths for classic epoxides, seeking molecules with similar chemistry but lower hazard profiles. Through our own product stewardship programs, research continues into stabilizers and alternative synthetic methods that improve the overall safety without compromising product utility. Partnerships with academic teams and consultants broaden the base of knowledge, keeping us abreast of changes in regulations or best practices.
Direct communication with users informs much of the day-to-day at our facility. Those on the factory floor—our team included—know well how downtime, fouling, or contamination can cripple a batch. By sharing real-time feedback on reactivity issues, storage stability, or subtle shifts in impurity loads, we hold ourselves accountable and can adapt process lines to address concerns before they become critical.
Troubleshooting for clients often means getting technical colleagues involved early, providing batch records, or working out suitable storage tips for unique site conditions. Our goal has always been to see users get what they expect from the chemical, without wading through surplus paperwork or confusing spec sheets.
Technical professionals across industries share one consistent viewpoint: quality chemicals should integrate seamlessly with existing operations. Irregularities—even minor—create headaches and lost time. Our practical experience in large-batch synthesis, high-purity isolation, and day-to-day logistics helps us anticipate bottlenecks and flag possible mishaps, reducing scrambling when production scales up.
No one in chemical manufacturing ever stands still. With the market for 1,2-Epoxybutane shifting—sometimes subtly, sometimes dramatically—the need for continuous innovation cannot be ignored. We continue to track developments in green chemistry aimed at more sustainable and less hazardous epoxide preparations. Researchers within and outside our firm test new catalysts and greener purification agents that may eventually become standard. Bringing these innovations to a commercial reactor is no simple task, but the lessons learned from years of scaling up and troubleshooting put us in a strong position.
Alternative feedstocks are being investigated, especially bio-based routes to key intermediates. Some approaches promise lower emissions and less dependence on fossil fuels, but balancing cost, consistency, and downstream compatibility presents new puzzles. Each proposed change goes through small-scale testing, hazard screening, and stakeholder review before any larger roll-out. Our teams know shortcuts may cost more in the end, so no process changes are rushed.
There’s also keen interest in digitalization and process automation. Tools for real-time monitoring of purity, impurity load, or volatile release save time and reduce operator exposure, and our investments in these tools allow staff to spend less time in direct contact with raw chemicals. Through this blend of human expertise and digital oversight, tighter tolerances are reached, and fewer “what-went-wrong” meetings fill the calendar.
Most visitors to a chemical plant rarely see the everyday attention applied to a product like 1,2-Epoxybutane. Decades of handling this compound in bulk, across weather changes and fluctuating demand, have taught us the practical rules of safe, reliable production. Robust quality assurance—well beyond certificates and specification tables—forms the backbone of our offering. The training received by staff, the personal responsibility felt by those who load and unload, and the dedication with which we track containers as they travel, all speak to experience gained over years, not days.
Above all, serving a market that spans from small specialty batches to full-plant requirements, we recognize that consistency—batch after batch—matters to users far more than abstract definitions of purity. The difference between a well-delivered, stable shipment and one laden with warning signs impacts profit, reputation, and safety at every link in the supply chain. Our sense of accountability comes from seeing our products in action, knowing each container directly influences the outcomes of research, manufacturing, or product assembly far beyond our own site.
For us, 1,2-Epoxybutane represents not just a chemical compound, but a promise of reliability, clarity, and partnership throughout the countless processes it helps enable. Each improvement in our process reflects the confidence placed in us by those who rely on this building block for their own innovations, efficiencies, and breakthroughs. Through focused investment, responsible operation, and relentless customer support, we continue to see this product deliver value across applications and continents, one drum, shipment, and tank at a time.