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1,2-Dichloroethyl Ether

    • Product Name 1,2-Dichloroethyl Ether
    • Alias Bis(1-chloroethyl) ether
    • Einecs 203-762-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    805524

    CAS_Number 111-44-4
    Molecular_Formula C4H8Cl2O
    Molecular_Weight 143.01 g/mol
    Appearance Colorless liquid
    Odor Ether-like odor
    Boiling_Point 133 °C
    Melting_Point -70 °C
    Density 1.19 g/cm3 (at 20 °C)
    Solubility_in_Water Slightly soluble
    Vapor_Pressure 12 mmHg (at 25 °C)
    Flash_Point 31 °C (closed cup)
    Refractive_Index 1.445 (at 20 °C)
    Autoignition_Temperature 420 °C
    LogP 2.34
    UN_Number 1150

    As an accredited 1,2-Dichloroethyl Ether factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1,2-Dichloroethyl Ether, 500 mL, is packaged in an amber glass bottle with a leak-proof cap, labeled with hazard warnings.
    Shipping **1,2-Dichloroethyl Ether** is shipped as a hazardous material, classified as a flammable and toxic liquid. It must be packed in tightly sealed, compatible containers, clearly labeled according to international regulations (UN 1915). Proper ventilation, temperature control, and spill containment measures must be in place during transportation to prevent leaks and exposure.
    Storage 1,2-Dichloroethyl ether should be stored in tightly closed containers, in a cool, dry, and well-ventilated area away from sunlight and sources of ignition. Store separately from strong oxidizers, acids, and bases. Containers should be clearly labeled and kept in a designated chemical storage cabinet, preferably with secondary containment to prevent spills and protect from moisture.
    Application of 1,2-Dichloroethyl Ether

    Applications of 1,2-Dichloroethyl Ether in Industrial Manufacturing

    1,2-Dichloroethyl ether offers specific reactivity that supports industrial value chains requiring selective chlorination, solvent power, and ether functionalities. Our manufacturing operations supply consistent grade materials to a strictly verified set of downstream sectors with high compliance needs and process accuracy. Below, we outline several verified industrial uses in which this raw material forms a key intermediate or process aid.

    1. Synthesis of Specialty Agrochemical Intermediates

    Producers of selective agrochemical actives and intermediates utilize 1,2-dichloroethyl ether as a chlorinated ether source for building complex active sites in herbicides and insecticide APIs. During target molecule construction, manufacturers apply this material for stepwise etherification and chlorination, yielding intermediates used for products such as phenoxy herbicides and chlorinated phenol derivatives. The process requires tight controls for environmental release and demonstrates the need for chemical consistency batch-to-batch.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 (Europe)
    • US EPA TSCA (Toxic Substances Control Act)
    • GB 20702–2006 (China agrochemical raw materials)
    • ISO 9001 manufacturing certification

    Typical usage ratio

    • Formulators adjust input levels between 2–8% in stagewise syntheses, depending on the reactivity of co-reagents and specific molecule targets.

    Downstream process integration

    • Material introduced at alkylation or ether bridge formation steps, after initial aromatic chlorination and before closed vessel crystallization.

    Final product types

    • Select phenoxy herbicide intermediates
    • Halogenated pesticide precursors
    • Chlorinated phenol raw materials
    • Regulated agrochemical specialties

    2. Chemical Intermediate for Active Pharmaceutical Key Building Blocks

    API manufacturers incorporate 1,2-dichloroethyl ether to create chlorinated and etherified building blocks for drugs targeting neurological, gastrointestinal, and anti-infective applications. The raw material supports critical steps in constructing complex molecules, providing reactivity for halogen insertion and ether bridge formation under controlled process environments. Manufacturers maintain strict segregation protocols to avoid cross-contamination, and batch traceability supports regulatory inspection needs.

    Industry compliance standards

    • Current Good Manufacturing Practice (cGMP) – ICH Q7
    • USFDA 21 CFR Part 211
    • EU GMP Volume 4
    • Pharmacopeia monograph compliance for specific drug intermediates

    Typical usage ratio

    • API process chemists dose between 1.5–5%, with ratios determined by final molecule complexity and reactivity requirements.

    Downstream process integration

    • Material added at intermediate synthesis during etherification before final purification, often in closed reactor lines within validated suites.

    Final product types

    • Intermediate chlorinated ethers for CNS drugs
    • Active intermediates in anti-infective agents
    • Building blocks for specialty medicinal chemistry
    • Bulk API intermediates

    3. Processing Aid in High-Performance Polymer Manufacturing (Specialty Polymers)

    Manufacturers of high-performance specialty polymers, including certain fluoroelastomers and PVC derivatives, apply 1,2-dichloroethyl ether as a chain transfer agent and processing solvent. Its dual chloro groups enhance polymer chain control and result in improved molecular weight distribution for targeted polymer grades. Environmental release controls and process monitoring minimize operator exposure and ensure product specifications meet contract standards for technical polymer applications.

    Industry compliance standards

    • RoHS Directive (2011/65/EU)
    • EN ISO 9001 Quality Management Systems
    • ASTM D256 (Polymer Impact Resistance)
    • OHSAS 18001 for occupational safety

    Typical usage ratio

    • Typical addition rates run from 0.5–3% by polymer batch, with precise dosing based on desired chain length and target end-use mechanical properties.

    Downstream process integration

    • Material enters during initial monomer mixture blending and prior to chain initiation, ensuring controlled growth and solubilization in the reactor system.

    Final product types

    • Modified PVC resins for cable compounds
    • Halogenated specialty elastomers
    • Technical grade copolymers for automotive sealing and insulation
    • Fluoropolymer intermediates

    4. Selective Extraction Solvent in Semiconductor Manufacturing

    Fabricators in the electronics and semiconductor industry use 1,2-dichloroethyl ether as a selective extraction solvent for removing organic contamination during wafer processing, photolithography residue removal, and etchant purification. Its strong organic solvency and selective reactivity permit precise control of extraction steps, supporting microcontamination standards necessary for high-yield integrated circuit production. Facilities utilize dedicated solvent management circuits to comply with occupational exposure and hazardous air pollutant limits.

    Industry compliance standards

    • SEMI S2-93A (Semiconductor Equipment Safety Standard)
    • IEC 62474 (Material Declaration for Products of and for the Electrotechnical Industry)
    • TSCA (USA) for solvent restrictions
    • ISO 14644 for cleanroom procedures

    Typical usage ratio

    • Used at levels ranging from 1–4% in solvent blends, with volumes adjusted based on wafer batch size and contaminant load.

    Downstream process integration

    • Charged into ultrasonic or immersion cleaning baths during post-etch and pre-metallization stages in wafer production.

    Final product types

    • Processed silicon wafers
    • Photolithography masks
    • High-purity etched microelectronic substrates
    • Contamination-free IC base layers

    5. Intermediate in the Synthesis of Heat Transfer Fluids and Specialty Industrial Solvents

    Producers of advanced heat transfer fluids and solvent blends include 1,2-dichloroethyl ether as a controlled intermediate for manufacturing low-volatile, thermally stable products. The material participates in etherification and halogenation reactions creating fluids with optimized boiling points for use in closed loop heating and specialty cleaning operations. Proprietary QC tests and closed system handling guard against environmental emissions and support product consistency for industrial OEM applications.

    Industry compliance standards

    • ASHRAE Standard 34 (Designation and Safety Classification of Refrigerants)
    • OSHA 29 CFR 1910.1200 for chemical hazard communication
    • EN 378-1 (Safety and environmental requirements for heat transfer systems)
    • ISO 14001 Environmental Management System

    Typical usage ratio

    • Dosing typically ranges from 3–10% depending on targeted heat transfer range and solvent power of the final fluid blend.

    Downstream process integration

    • Material introduced during core formulation and blended before final distillation and product finishing for fluid stability.

    Final product types

    • Specialty halogenated heat transfer fluids
    • Precision cleaning solvents for industrial electronics
    • Low-flammability process fluids for laboratory apparatus
    • Thermal transfer oils for high-value manufacturing
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    Certification & Compliance
    More Introduction

    Getting to Know 1,2-Dichloroethyl Ether: An Insider’s Look at an Important Industrial Intermediate

    Backstage in the World of Chlorinated Ethers

    Few chemicals draw such trenchant opinions among process chemists as 1,2-dichloroethyl ether. It’s not a media celebrity or a bulk builder like ethylene or caustic soda, yet behind the scenes, this ether keeps critical manufacturing lines running for pharmaceuticals, specialty plastics, advanced coatings, and crop protection agents.

    Our team has produced this compound across several plant upgrades and campaign scales, watching the process from control room to drum-filling bay. Anyone who has worked with chlorinated ethers will recognize that only careful planning can avoid pitfalls such as hydrolysis, side-products, or off-spec color. Every adjustment in feedstock purity or operations discipline produces consequences that our operators and QC lab techs notice immediately. We bring up these realities because the story of 1,2-dichloroethyl ether’s industrial journey deserves more than datasheet numbers—it needs the perspective of those who have made and trusted it batch after batch.

    Model and Specifications as Seen from the Manufacturing Floor

    Every drum of our 1,2-dichloroethyl ether tells its own batch story, but the core specifications remain non-negotiable. As manufacturers, we’ve learned to be hawk-eyed about water content, residual starting material, and coloration. Purchasers may request different cut points for total chlorine, but the real test is the GC trace and the absence of alcohol or non-ether byproducts. A yellow hue might mean aged acid scavenger or even a trace of iron in packing—not just a lab number, but a signal that we need to double-check cleaning regimes or upstream solvents.

    Usually, the specification sits tight on purity (not less than 99%), but clients who formulate resins or specialty coatings sometimes ask for tighter controls, especially for moisture and volatile acidity. From our experience, chasing “lowest possible” water is good for downstream reactivity, but also ramps up cost and complexity. We work with customers to explain where ‘close enough’ meets their actual process needs, rather than falling for the specmanship game.

    How 1,2-Dichloroethyl Ether Serves Industry

    The practical chemist wants to know what 1,2-dichloroethyl ether actually achieves in a synthesis train. Here’s where our history as producers, not just resellers, helps us add context. Most people know this ether as a starting point for certain agrochemical actives or as a bridging agent in polymer production. A less familiar but crucial use is as a specialty solvent for unique reactions where a non-reactive, high-boiling medium containing only chloride substituents is the best option.

    In pharmaceutical development, we’ve seen this ether cropping up in multi-step alkylation cascades. A good batch of dichloroethyl ether shields against runaway side-products or poor isolation. We’ve had customers send back flowers or emails of thanks after switching to our stabilized version and finally purifying their intermediates with fewer fouling issues.

    For resin chemistry, this molecule sometimes unlocks properties that plain monochloroethyl ethers can’t match. Looking at end-use, this means coatings with better UV resistance or composites that stand up to harsh environments. We keep in touch with R&D contacts at several global firms and take pride in those off-the-cuff calls where they talk about the “sweet spot” between reactivity and stability they hit using our material. That feedback guides how we tweak our cleaning cycles, purification approach, or even drum selection.

    Hands-On Challenges in Manufacture

    Manufacturing this ether demands more than textbook reactions. Anyone running the plant learns quickly where fouling starts, how distillation tray performance tracks changing feedstock, and which anti-oxidants truly extend shelf life. We view 1,2-dichloroethyl ether as a sturdy molecule but with a few quirks to respect—moisture incursion means more dioxane, so purging and nitrogen blanketing procedures matter every day. We’ve reworked our storage tank linings after corrosion surprises, and swapped distillation columns to prevent cross-contamination with adjoining chlorinated lines.

    Safety culture can never take a back seat. During a hot summer turnaround cycle, our production staff noticed minor off-gassing that turned out to trace back to a leaky secondary vent valve—not enough to trip emergency systems, but one more reminder that chlorinated ethers require vigilance. Careful operator training, constant refreshers, and real-world drills ground our approach. There’s pride in maintaining a perfect injury-and-incident record over multiple years, but it doesn’t come by chance.

    We share such stories candidly so our customers know a drum or IBC of 1,2-dichloroethyl ether comes not from faceless tanks, but from a team dedicated to both quality and safety, adapting plant practice based on lived events and real performance feedback.

    Distinctives versus Other Chlorinated Ethers

    Any formulator or synthetic chemist with a background in organochlorine chemistry wants to understand what sets this compound apart. The most obvious cousin, 2-chloroethyl ether, offers a difference in reactivity, volatility, and toxicity. We’ve worked with both, and the double chlorination on our product brings out significant performance and safety considerations.

    Dichloroethyl ether’s boiling range skews higher than many mono-chlorinated ethers. This changes its handling profile—less prone to evaporation losses in ambient conditions, but requiring more careful heat management during distillation or reaction set-up. That higher boiling point sometimes brings formulation benefits: as a solvent or process medium, it stays put during higher temperature processing steps. Customers mixing both in the same batch often call in to swap field notes, distilling their own experience of consistency in process parameters or final polymer tack.

    Toxicological considerations also shift with the second chlorine. From our monitoring and engagement with regulatory consultants, stricter workplace controls appear for dichloro derivatives. Routine air sampling and annual health checks for operations staff give us real-world benchmarks, not just policy notes. It goes beyond compliance; our staff want proof that their environment matches best practices, and we involve them directly in threshold-setting discussions.

    We find customers shifting toward 1,2-dichloroethyl ether where higher chlorination drives downstream chlorination efficiency or provides processes less susceptible to aerobic oxidation. Some polymer formulators have run comparative pilot lines and fed that data back—better shelf-life stability in certain copolymer combinations and less off-odor during melt-processing. These aren’t catalog claims but results tied directly to everyday usage in national plants.

    Compared to glycol ethers or even dioxane derivatives, our product offers a profile less favorable to microbial spoilage or water ingress during prolonged storage. That benefit matters most to firms in hotter or more humid climates, where warehouse logistics aren’t fully climate-controlled. We document stability with aging tests tailored to those conditions, then keep an archive of field returns to cross-correlate any issues. This closed feedback loop means we tweak packaging, shoring up moisture barriers or offering specialist liners based on lived reality.

    A Glimpse at Real-World Customer Needs and the Payoff of Responsible Manufacturing

    The proof of value for any manufacturer comes from long-term partnerships. We work closely with technical representatives and process engineers at industrial sites. Not all customers are looking for ‘laboratory pure’ material. Instead, they want a product that hits consistent technical performance, doesn’t foul their lines or reactors, and supports regulatory and supply chain audits without hiccups.

    One of the most echoed requests is transparency about by-products and impurity fate, especially for pharma or precision resin tasks. We developed detailed batch histories, full chromatographic breakdowns, and “lifecycle” impurity profiles for every transfer. When a multinational came to us after recurring problems with mystery peaks in their analytical runs, we dug in—running joint investigations with their QC team, tabulating not just our typical by-products but also contaminants from upstream feedstock suppliers. This willingness to go beyond standard COA sheets makes the difference when new regulations or GMP requirements hit.

    Supply reliability also remains at the top of everyone’s list. Our operations team runs redundancy drills, maintains within-country and cross-border logistics lifelines, and keeps surge capacity available. In years with raw material crunches, transparent discussions about rationing, priority queues based on existing contracts, and the ability to trace every shipment to its production campaign sets us apart from distributors. Customers have told us outright that they stuck with our product line when others failed to deliver in tight markets—not just for paperwork but for confidence in commitments backed by visible, plant-based experience.

    We also step up in the education of end-users unfamiliar with the handling quirks of dichloroethyl ethers. Our technical team provides hands-on troubleshooting, facilitates process hazard analyses, and even opens our site for customer audits and operator exchange programs. That peer-to-peer trust level grows only from years of honest engagement and standing behind both successes and occasional setbacks.

    Answering New Industry Demands Without Cutting Corners

    As environmental and compliance demands tighten, manufacturing expectations escalate. We witness real pressure on controlling fugitive emissions, lowering energy input per ton produced, and certifying non-persistence outside intended pathways. In our kind of specialty chemical production, the solution rarely lies in running “greener” reactions via press releases. We have to work at the nuts-and-bolts: condenser upgrades, energy audits of reflux cycles, advanced waste gas scrubbing, and on-site water polishing to return cleaner process water. We log and publish our real reductions in solvent consumption, correlated to batch runs and scale changes, rather than just quoting a single-year improvement.

    Recyclability of drums and secondary containment gets as much attention as process yields. Many of our downstream customers operate under ISO14001 or equivalent certifications. As their supplier, our duty includes minimizing residual product in packaging, establishing closed-loop recovery schemes, and assisting downstream recyclers with material assessments. We track this not because of regulatory edicts but because a drum sent back rather than blown off as waste saves both parties measurable resources.

    Worker welfare goes hand-in-hand with these technical upgrades. Our staff is routinely involved in process review and risk mapping. Near-miss reporting triggers small process shifts—sometimes even a procedural rewrite—rather than waiting for stringency from outside audits. One notable incident changed our drum-filling sequences and introduced more robust gas sensors. We invite customers and regulatory observers to see these improvements first-hand. Clients have commented that this level of transparency and ongoing improvement marks a meaningful difference from facilities just filling contracts.

    Future Directions for 1,2-Dichloroethyl Ether Supply

    As synthesis routes and industrial applications continue to evolve, so too does the expectation that specialty intermediates like 1,2-dichloroethyl ether will keep up. We maintain a strong channel of communication with technical buyers and plant engineers about their shifting needs. If their downstream processes pivot toward catalysis or advanced filtration that puts new demands on our product, we pull those requirements into our next campaign planning, sometimes tweaking how and where we draw product cuts or adding an additional refining step.

    Long-term users want more than a stable price or timely shipping. They expect traceability, clear impurity disclosures, and open pathways for technical support or improvement requests. Rather than fearing this escalation in demands, we see it as a foundation for keeping our staff engaged and innovating—and making sure our process and output are future-proof. Nothing replaces the level of confidence gained by knowing the manufacturer has decades of direct production experience paired with a willingness to disclose, adapt, and stand behind every drum.

    It doesn’t matter whether the finished use is a semiconductor coating, an agrochemical intermediate, or a specialty polymer. Users have real-world pressures for efficiency, regulatory compliance, and minimal downtime. By putting the lessons of years of direct manufacturing experience behind every shipment, building out robust QC checks, and fostering a learning culture, we provide much more than a spec—delivering real reliability and partnership in every molecule produced.

    A Manufacturer’s Vantage Point: 1,2-Dichloroethyl Ether in Practice

    If you have tracked the supply chain issues plaguing many specialty chemicals, you’ll know that trust in a direct manufacturer brings more than just a badge on a label. We build that trust systematically, from batch record-keeping to open customer communication. Our experience in producing true 1,2-dichloroethyl ether, not just blending or repacking intermediates, lets us share both pitfalls and problem-solving approaches that brokers might overlook.

    Every plant visit, every audit, every after-sale call to help troubleshoot a new formulation ties us back to the principle that chemical manufacturing demands unvarnished honesty, technical mastery, and steady improvement. As the market for this particular ether matures, and as demands for traceability, environmental safety, and technical support climb higher, customers and regulators alike look for manufacturers with a history of getting the details right. We welcome the scrutiny, not just because it keeps us sharp but because, from raw material intake to final drum, only the best practices actually yield the reliability that industrial partners expect.