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1,2,3,5-Tetrachlorobenzene

    • Product Name 1,2,3,5-Tetrachlorobenzene
    • Alias Tetrachlorobenzene
    • Einecs 210-855-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    467414

    Cas Number 634-66-2
    Molecular Formula C6H2Cl4
    Molar Mass 215.89 g/mol
    Appearance White to off-white solid
    Melting Point 148-149°C
    Boiling Point 282°C
    Density 1.67 g/cm³
    Solubility In Water Insoluble
    Flash Point 134°C (closed cup)
    Purity Typically ≥98%
    Chemical Structure Benzene ring substituted with chlorine atoms at positions 1, 2, 3, and 5
    Synonyms 1,2,3,5-Tetrachlorobenzol
    Refractive Index 1.608 (at 20°C)
    Vapor Pressure 0.002 mmHg at 25°C
    Ec Number 211-213-3

    As an accredited 1,2,3,5-Tetrachlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1,2,3,5-Tetrachlorobenzene is packaged in a 100 g amber glass bottle, labeled with hazard warnings and product details.
    Shipping 1,2,3,5-Tetrachlorobenzene should be shipped in tightly sealed containers, kept away from heat and direct sunlight. It must be labeled as hazardous and handled according to local, national, and international transport regulations. Use appropriate UN packaging, ensure compatibility, and include safety documentation. Protect from physical damage during transit.
    Storage 1,2,3,5-Tetrachlorobenzene should be stored in a tightly closed container in a cool, dry, well-ventilated area away from sources of ignition, heat, and incompatible substances such as strong oxidizers. Avoid exposure to sunlight and moisture. Proper chemical labeling and secondary containment are recommended to prevent accidental spills or leaks. Use corrosion-resistant shelving and store away from food and drink.
    Application of 1,2,3,5-Tetrachlorobenzene

    Applications of 1,2,3,5-Tetrachlorobenzene in Industrial Manufacturing

    As a specialized producer of 1,2,3,5-Tetrachlorobenzene, we supply this chlorinated aromatic compound to several advanced manufacturing sectors. Applications focus on established industrial processes where its chemical structure, reactivity, and purity are integral to production outcomes and regulatory compliance.

    1. Intermediate for Agrochemical Synthesis

    Agrochemical manufacturers use 1,2,3,5-Tetrachlorobenzene as a controlled intermediate when synthesizing high-performance herbicides and specific insecticides. The compound contributes crucial chlorine atoms during stepwise halogenation, supporting active ingredient development while maintaining strict tracking and handling measures. Integrating this material supports batch consistency under regulated environments, aiding the preparation of downstream intermediates that define biological activity in crop protection agents.

    Industry compliance standards

    • REACH Registration (EC No. 1907/2006, Annex IX/VII, Intermediate use)
    • China National Standard for Production of Pesticide Intermediates (HG/T 3950-2018)
    • ISO 9001:2015 Quality Management for Chemical Synthesis
    • EPA TSCA Inventory Tracking (US)

    Typical usage ratio

    • Batch formulations incorporate at 0.5%–2% by total reaction mass, adjusted based on downstream halogenation demand and desired impurity profile

    Downstream process integration

    • Introduced at the controlled chlorination phase for manufacturing of triazine- and aniline-based active ingredients; reaction temperature and time tailored for targeted substitution

    Final product types

    • Selective herbicide technicals (e.g., atrazine intermediates)
    • Insecticide intermediates for formulation of commercial and agricultural products
    • Defoliant ingredient bases

    2. Precursor in Dye Manufacturing

    Dye industry specialists use this compound as a core raw material to synthesize chlorinated intermediates that impart fastness properties in vat, disperse, and solvent dyes. The chlorine pattern in the benzene ring enables downstream nucleophilic aromatic substitution and coupling reactions, giving rise to dye molecules with high stability under light and wash-fastness conditions. Companies must maintain strict purity and isomer control at this stage to ensure reliable color characteristics and regulatory acceptance of system dyes.

    Industry compliance standards

    • OEKO-TEX® Standard 100 (regarding restricted compounds in textile dyes)
    • ZDHC MRSL (Manufacturing Restricted Substances List) for textile chemicals
    • ISO 9001:2015 Certified Processes
    • EU Regulation 1907/2006 (REACH)—Annex XVII substance control where applicable

    Typical usage ratio

    • Added at 1%–5% of total dye intermediate mass, depending on the required degree of chlorination for specific color index targets

    Downstream process integration

    • Used during condensation and chlorination steps prior to final coupling; process parameters determined by target dye fastness and chromophore design

    Final product types

    • Disperse dyes for polyester textiles
    • Vat dyes with enhanced fastness for cotton applications
    • Solvent dyes used in plastics and printing inks

    3. Raw Material for Specialty Halogenated Aromatics

    Producers of specialty fine chemicals employ 1,2,3,5-Tetrachlorobenzene in synthesizing higher-value halogenated aromatics, including pentachlorobenzene and hexachlorobenzene. It provides a reliable source of tetra-chlorinated benzene as feedstock for further chlorination or nucleophilic substitution reactions, where obtaining the correct substitution pattern is crucial for final product purity and function. Synthesis routes require thorough QC to prevent cross-contamination and control residual isomer content, as final products often serve as advanced intermediates in electronics and research applications.

    Industry compliance standards

    • ISO 9001:2015 for Fine Chemical Production
    • Responsible Care® Global Charter for chemical stewardship
    • REACH compliance for intermediate handling and tracking
    • UN GHS (Globally Harmonized System) for chemical labeling and safety

    Typical usage ratio

    • Input varies 2%–8% by batch size and desired degree of halogen substitution; adjusted by downstream reaction throughput and product yield requirements

    Downstream process integration

    • Feeds directly into controlled batch or continuous chlorination reactors; precise feed rate and temperature management ensures efficient conversion and limits polychlorinated by-product formation

    Final product types

    • Pentachlorobenzene and hexachlorobenzene intermediates
    • Advanced polychlorinated compounds for electronics industry needs
    • Reference standards for chemical analysis

    4. Use in Polymer Additive Masterbatches

    Producers of high-performance plastics and technical resins incorporate 1,2,3,5-Tetrachlorobenzene as a base material for synthesizing specific polymer additives, such as chlorinated flame retardants and anti-oxidant boosters. The raw material enters downstream synthesis of additive masterbatches where thermal stability and regulatory requirements on halogen content are tightly monitored. Its consistent purity supports reproducible dispersion within polymer matrices, resulting in finished goods that meet global safety and performance certifications.

    Industry compliance standards

    • UL 94 Standard for Flammability of Plastic Materials
    • RoHS Directive 2011/65/EU (regarding restricted substances in electrical/electronic applications)
    • ISO 14001:2015 Environmental Management for manufacturing sites
    • ASTM D5630 for halogen content in polymers

    Typical usage ratio

    • Introduced at 0.2%–1% of final polymer mass via masterbatch compounding; adjusted by polymer type and target flame-retardant or anti-ageing performance

    Downstream process integration

    • Undergoes upstream chlorination to produce specific additive molecules, which blend with carrier resins during masterbatch extrusion prior to molding or extrusion of finished parts

    Final product types

    • Flame-retardant polyolefin and engineering resin masterbatches
    • Chlorinated additive concentrates for technical thermoplastics
    • Polymeric components for electrical and building applications
    Free Quote

    Competitive 1,2,3,5-Tetrachlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

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    Certification & Compliance
    More Introduction

    Introducing 1,2,3,5-Tetrachlorobenzene: Consistent Quality from an Experienced Manufacturer

    Understanding 1,2,3,5-Tetrachlorobenzene in the Chemical Industry

    For businesses invested in the evolution of specialty chemicals, 1,2,3,5-Tetrachlorobenzene remains one of those compounds that anchors both established operations and emerging sectors. As a manufacturer with decades behind us, we’ve learned to focus on the fundamentals: purity, handling, and reliability. The molecular structure, featuring four chlorines on a singular benzene ring at 1,2,3,5 positions, sets this compound apart from its other tetrachlorinated counterparts.

    Production Experience Directs Every Batch

    Manufacturing 1,2,3,5-Tetrachlorobenzene is no shortcut process. Our practice has always relied on controlled chlorination, always paying attention to temperature and catalyst loading. Over countless batches we’ve observed that slight variations in starting material quality ripple through to the final product. The result of tight process controls shows in uniform melting points and the absence of off-odor, two small markers industry insiders recognize immediately.

    Purity sits at the core of specialty aromatic production. Inconsistencies might not shout from a quick test report, but impurities can challenge downstream processing. Facilities using this product for organic synthesis or as a reference standard in analytical work rely on consistent physico-chemical properties, more than any brochure could ever convey. We’re as strict with trace impurities and isomeric composition as we are with our own process audit trails.

    Specifications Grounded in Real-World Use

    Standard practice presses us to meet specifications adopted by longstanding players in the sector. Our product arrives as a white crystalline powder or flakes, depending on shipment scale and storage. Melting points cluster tightly between 140°C and 143°C, underpinned by GC and IR checks that leave little to chance. We maintain moisture content and residual solvents below thresholds set by major users in advanced intermediate and reference applications. Every batch must meet these bars, not by external mandate, but because users depend on predictability batch after batch.

    We’ve leaned into robust packaging and handling guidelines—sealing moisture out, using lined drums—simply because we’ve seen losses that stem from missteps in storage. A clean lot, transported in secure, stable packaging, spares customers unplanned downtime and reputation headaches.

    Why Specific Isomers Matter: The 1,2,3,5 Difference

    Benzene chlorination produces several isomers, and we’ve learned through feedback and our own process engineering where differences show up. 1,2,3,4-Tetrachlorobenzene and 1,2,4,5-tetrachlorobenzene share a molecular formula but diverge in physical and chemical properties. From experience, 1,2,3,5-Tetrachlorobenzene’s reactivity profile often lines up more neatly with requirements in specialized syntheses and standard-setting initiatives, especially in the agrochemical and polymer industries.

    Analytical chemists needing sharp, reproducible chromatographic signals will tell you: isomeric purity does more than fill a tick box. The wrong isomer blend compromises interpretability or yields unexpected byproducts in derivatization. Years of reporting from colleagues using various tetrachlorobenzenes confirm how even seemingly minor impurities creep into multistep chemistry or stability work.

    Applications Drawn from Industrial Practice

    We routinely supply 1,2,3,5-Tetrachlorobenzene for roles spanning from raw material in dye manufacture to advanced organic synthesis. Its function as a reference material in environmental laboratories hinges on narrow chemical tolerances and reliable supply. Many of our partners in the pigment and agrochemical sectors have shifted to this isomer based on its ring substitution pattern, which guides subsequent reactions more predictably than alternatives.

    Downstream, 1,2,3,5-Tetrachlorobenzene proves valuable in preparative routes for specialty herbicides and intermediates. Years ago, one manufacturing partner moved away from mixed tetrachlorobenzenes, prompted by process inefficiency traced to byproduct formation. By focusing on the 1,2,3,5 isomer, they trimmed waste streams, slashed cleaning downtime, and tightened product assay specs with fewer surprises.

    Beyond process chemistry, we’ve seen uptake for trace-level analysis in environmental monitoring, particularly in projects focusing on chlorinated contaminants in soil and sediment. Our product’s repeatable purity profiles and stable shelf life have enabled reliability in lab calibration, an often-overlooked advantage when comparing suppliers.

    Tangible Differences from Other Tetrachlorobenzene Products

    Not all tetrachlorobenzene products behave the same in real-world plants and labs. Our own work with diverse clients has highlighted sharper contrasts over the years. The 1,2,3,4- and 1,2,4,5- isomers react differently in nucleophilic aromatic substitution steps; yields fall or new impurities arise if users substitute one isomer for another. Quality control teams have flagged these tricks of the trade, particularly in high-throughput settings where deviation causes cumulative issues.

    Cutting corners on isomeric composition also invites problems for anyone preparing analytical standards. Calibration drift in GC or HPLC arises when trace amounts of the wrong tetrachlorobenzene isomer muddy the chromatograms. Recognizing and resolving even slight product drift has become second nature for experienced users, but our production controls aim to make that vigilance a backstop, not a first line of defense.

    Lessons from Decades of Hands-On Manufacturing

    The finished product embodies every step up and down the synthesis line. Raw material sourcing—selecting only the cleanest monochlorobenzene and dioxane solvents—has eliminated persistent, low-level contamination seen back in earlier decades. Each time we invest in updated distillation or filtration, the impact ripples outward: faster throughput, less feedstock loss, more reproducible lot-to-lot analysis, and fewer client callbacks chasing unexpected results.

    Those steps forward grow out of hard-earned lessons. Even the smallest leaks in transfer or venting systems amplify across hundreds of kilos, and the learning curve from older plants to newer equipment proves how investment in engineering pays off. Our approach in the plant always returns to a simple question: does a given step improve the lives of those who use our product? When cleaning protocols lag, or a tank ages out of spec, everyone downstream shoulders the cost. So we keep a relentless look at the details, item by item.

    Routine engagement with partners informs improvements. Analytical staff, production chemists, and procurement specialists have all contributed insights that we’ve baked into how we make and deliver 1,2,3,5-Tetrachlorobenzene. From refining filtration media to piloting bulk-flake packaging, the process reflects a real-world give and take. We don’t chase new process tweaks for their own sake—the driver remains easier handling, better shelf life, and consistent purity.

    Regulatory Context and Practical Realities

    Continuous operation means staying inside a shifting landscape of chemical compliance and stewardship. We’ve watched regulations evolve, especially around chlorinated aromatics, and the nuances touch everything from labeling to reporting requirements. Rather than push those burdens downstream, facilities like ours build in documentation trails and transparency upfront, clearing the way for client audits, and removing compliance guesswork.

    Where permitted by law, end-users find added confidence in documented batch traceability, and our experience proves that audit readiness drives fewer project delays. Comprehensive handling protocols—rooted in both compliance expectations and field experience—translate directly to workplace safety and environmental protection.

    The 1,2,3,5-Tetrachlorobenzene we produce supports customers whose business relies on meeting local and global standards. Reliable traceability, thorough records, and attention to safe packaging reinforce the cycle of trust built across industries over the years.

    Pushing for Practical Solutions in the Supply Chain

    Secure availability has become as pivotal as purity. Any manufacturer with long-haul clients knows the headaches introduced by misscheduled logistics or uneven product quality. Coordinating shipping partners, preparing for customs documentation, anticipating shifts in international regulations: these infrastructure investments smooth out nearly invisible friction for downstream customers.

    Through scrutinizing shipping routes, forecasting inventory with plants, and managing buffer stocks, we mitigate supply interruption risks—as production stoppage, re-formulation, or regulatory violation due to unplanned batch delays can ripple through more than a single operation. The value of stable supply unfolds every time a client launches a new product or faces a regulatory change that prevents alternatives from reaching their line.

    Customer Collaboration Shapes Product and Practice

    Field-driven adaptation paces much of our ongoing evolution. Over decades of manufacturing, feedback from users curbs unnecessary complexity. We work closely with technical leads who demystify where the product shines, and just as importantly, where it needs improvement. These insights drive upgrades—smarter packaging, more granular documentation, or tweaks in analytical testing tailored to a customer’s pain points.

    Shared problem-solving—debugging a crystal polymorph issue, or investigating bleed-through in intermediate production—yields not just a better product, but a more realistic understanding of how it will function across daily use cases. Of particular note, we regularly adjust product form (powder vs. flakes) and shipment batch size to match client systems, not to chase convenience in our own plant.

    Addressing Emerging Industry Trends

    As markets for specialty chemicals move, so does demand for tailored aromatic building blocks. Our ongoing research teams keep eyes on new routes to improve throughput, raise purity standards, or streamline downstream purification needs. We reevaluate standard tolerances as downstream partners tighten their specs; every change on our end resolves directly into their success.

    Sustainability no longer sits on the fringe of manufacturing. Cleaner process choices—solvent recycling, emissions abatement, resource-efficient energy—directly feed into compliance and reputation. Our plant embedded such improvements not simply for regulatory satisfaction but also because it keeps local environments and staff safer, and by experience, reveals hidden efficiencies otherwise unrealized.

    Agile adaptation in manufacturing ties directly into how 1,2,3,5-Tetrachlorobenzene fits major industrial shifts—new herbicide formulations, advanced pigment manufacturing, next-generation environmental standards, and even high-throughput screening protocols. Each isomer’s defined property opens or closes doors for innovators in these spaces.

    Looking Forward: Reliability Backed by Expertise

    Long-term customers consistently ask for more clarity around traceability, documentation, and product consistency. Over years of supply, met expectations build loyalty. We see every new project as a chance to reaffirm this approach, using direct communication and open technical dialogue as a foundation. Cross-disciplinary teams in procurement, production, quality control, and R&D work together, feeding a feedback loop that ensures ongoing improvement.

    For those buying 1,2,3,5-Tetrachlorobenzene, it’s the sum of small, practical steps—a controlled batch record, an exact melting point assay, moisture-tight packaging, and responsible logistics—that turns a simple molecule into a promise kept. As demands and regulations shift, our manufacturing mindset keeps faith with the end user, rooted in the details that matter and an eye towards the future.