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Oxanilic Acid

    • Product Name Oxanilic Acid
    • Alias N-Phenylglycine
    • Einecs 207-864-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    671376

    Chemical Name Oxanilic Acid
    Cas Number 537-59-7
    Molecular Formula C8H7NO3
    Molecular Weight 165.15 g/mol
    Appearance White to faintly pink crystalline powder
    Melting Point 205-210°C
    Solubility In Water Slightly soluble
    Boiling Point Decomposes before boiling
    Density 1.435 g/cm³
    Pka 3.5 (carboxylic acid group)
    Synonyms N-Phenylglycine, 2-Phenylaminoacetic acid
    Ec Number 208-678-4

    As an accredited Oxanilic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Oxanilic Acid is supplied in a 500g amber glass bottle with a secure screw cap, labeled with hazard and handling information.
    Shipping Oxanilic Acid should be shipped in tightly sealed containers, protected from moisture and incompatible substances. Store in a cool, well-ventilated area. Follow all local, national, and international regulations for chemical transport. Use appropriate hazard labeling and shipping documentation, handling packages with care to prevent spillage or exposure during transit.
    Storage Oxanilic acid should be stored in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizers. Keep the container tightly closed when not in use to prevent moisture absorption and contamination. Store in a chemical-resistant, labeled container, and avoid exposure to direct sunlight, heat, or sources of ignition. Ensure access is limited to trained personnel only.
    Application of Oxanilic Acid

    Applications of Oxanilic Acid in Industrial Manufacturing

    Our manufacturing expertise in Oxanilic Acid supports a range of specialized industrial sectors, providing this raw material to key downstream users who depend on its unique chemical properties for quality, safety, and regulatory compliance. Below, we detail major application scenarios with in-depth technical insights for each downstream segment.

    1. Azo Dye Intermediates for Textile Pigmentation

    Major textile pigment producers utilize Oxanilic Acid as a crucial coupling component in the synthesis of high-performance azo dyes, especially for dispersion and acid dye classes. This intermediate ensures stable chromophore development after diazotization and coupling reactions, supporting the manufacture of colorants with excellent wash and light fastness for synthetic fibers. Processing teams maintain strict control on additive integration at the coupling phase to achieve batch consistency, chromatic accuracy, and compliance with global safety limits for aromatic amines.

    Industry compliance standards

    • ZDHC Manufacturing Restricted Substances List (MRSL)
    • OEKO-TEX® Standard 100
    • EU REACH Annex XVII (Aromatic Amines Restrictions)
    • ISO 105 series for textile color fastness testing

    Typical usage ratio

    • 0.25–1.5 mol Oxanilic Acid per mol diazonium salt; formulation ratio depends on target dye class and pigment shade

    Downstream process integration

    • Enter at azo coupling stage: aqueous solution mixed directly post-diazotization phase during production of dye intermediates

    Final product types

    • Synthetic fiber dyes (e.g., Disperse Red 17, Acid Red series)
    • Textile pigment concentrates
    • Granular and liquid dye blends for polyester, acetate, and nylon
    • Industrial textile inks and coloration pastes

    2. Photographic Chemicals (Color Developer Modifiers)

    Within the photographic chemical sector, R&D teams integrate Oxanilic Acid into the synthesis of color developer modifiers and stabilizers. Its function as a nuanced substituent alters the sensitivity and fading resistance of silver-halide materials used in both analog and digital photographic paper. Quality assurance tracks strict impurity thresholds, as trace byproducts impact image clarity and color balance in end-user applications.

    Industry compliance standards

    • ISO 18902: Imaging materials – Processed photographic films and papers
    • ANSI/NAPM IT9.1: Stability of photographic images
    • RoHS (Restriction on Hazardous Substances) for consumer photo products

    Typical usage ratio

    • 0.1–0.4% w/w in developer modifier formulation; precise addition calibrated on batch size and target color stability parameters

    Downstream process integration

    • Added during developer or stabilizer compounding, prior to filtration and quality testing in photographic chemistry manufacture

    Final product types

    • Color developer concentrates for film processing
    • Photographic print stabilizers
    • Pre-formulated color processing kits for laboratories

    3. Synthesis of Pharmaceutical Intermediates

    Oxanilic Acid acts as a specialized building block in the production of select non-steroidal anti-inflammatory drug (NSAID) intermediates and related compounds. Custom synthesis lines employ it in amide bond-forming reactions, with precise stoichiometric control required to minimize residual organics. Manufacturing operates under strict cGMP and pharmacopoeial environments to eliminate the risk of impurity carry-over into active pharmaceutical ingredients (APIs).

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for API Synthesis
    • USP-NF, Ph. Eur. (European Pharmacopoeia) for intermediate purity
    • 21 CFR Part 211 (US FDA cGMP for Finished Pharmaceuticals)

    Typical usage ratio

    • 1.0–1.2 mol per mol of target amine or acid reactant; adjusted during process scale-up and in response to analytical QC findings

    Downstream process integration

    • Charged into amidation or esterification reactors during multi-step synthesis of pharmaceutical intermediates, under inert atmosphere

    Final product types

    • Advanced intermediates for NSAID manufacture
    • Key side-chain functionalization blocks
    • Custom contract synthesis intermediates

    4. Dye Intermediates for Specialty Paper Manufacturing

    Specialty paper converters deploy Oxanilic Acid as a precursor in high-value anionic dye systems for carbonless copy, security, and thermal papers. Its precise molecular structure supports optimal acid dye formation, favoring clear tone development and non-migrating color change properties critical for tamper-evident applications. Comprehensive trace analysis validates chemical purity to ensure process compatibility and minimal interference in automated coating lines.

    Industry compliance standards

    • DIN ISO 9241-12: Color application in office and security papers
    • EU Toy Safety Directive 2009/48/EC (where paper used in toys)
    • EN 643: European list of standard grades of paper and board

    Typical usage ratio

    • 0.5–2.0% w/w of pigment system; formulation ratio set by target color density and specific paper substrate absorbency

    Downstream process integration

    • Blended into dye precursor solutions prior to paper machine headbox dosing, followed by in-line pH adjustment and drying

    Final product types

    • Carbonless copy paper dye layers
    • Security feature-embedded specialty sheets
    • Thermochromic and self-copying paper substrate

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    Certification & Compliance
    More Introduction

    Oxanilic Acid: Backbone of Precision Chemistry

    Our Experience With Oxanilic Acid

    Making oxanilic acid every day, we experience the entire journey from raw material selection to final product shipment. Each batch reflects careful monitoring and years of technical refinement. Synthetic pathways differ across the industry, but in our facility, we depend on reliable starting materials to avoid variable yields or unwanted impurities. Our technicians monitor the reaction environment closely, balancing temperature and pH, using experience instead of guesswork. Speculative chemistry doesn’t cut it; what lands in the customer’s hands must match the intention behind every step at our reactors.

    Most chemists chasing oxanilic acid need consistent quality, not surprises. We keep the product’s water solubility and crystalline habit in a tight range, avoiding ambiguity in downstream reactions. Our team tracks the particle size and flow for each lot, not just a random sample. If the acid runs clumpy, it slows customer processing or disrupts feeding equipment. Reliable handling eases workflow — those are the details manufacturers think ahead about.

    Why Oxanilic Acid Matters

    Looking back at decades in chemicals manufacturing, we see how oxanilic acid forms a dependable staple for dye production, pigments, herbicide building, and specialty chemical intermediates. Customers come to us after trying off-spec batches from resellers. They see ink formulations blotch or pigment dispersions drift without warning; poor purity and contaminants create expensive headaches. Our staff fields calls when cheap batches throw a plant out of calibration. Fixing those problems after shipping often costs more than sourcing right from the beginning.

    Manufacturers need more than a chemical with the correct label. They want predictable solubility, precise melting points, and a particle structure that doesn’t gum up mixing tanks. One research chemist told us unexpected moisture content from other sources clogged the feeder on his continuous processing line, wasting hours of production. These challenges come back to how the product is made, not just sold. That’s why we track and archive every production run, tying every lot back to original raw materials and process logs. This habit shelters our customers from mismatches they might face elsewhere.

    Our Approach to Quality and Consistency

    Every industry talks about quality but achieving it takes more than paperwork. In our lab, quality means pulling samples at every stage, cross-checking against reference standards accumulated across years. We run HPLC, FTIR, and titration measurements on every lot. If anything looks off, we investigate before release. Sometimes the difference shows up as a residue that throws off a coloring process or a trace impurity that messes with an active pharmaceutical ingredient. Our staff knows to scrutinize what matters: moisture, trace inorganics, and visual clarity. A handful of percentage points in purity can mean the difference between smooth downstream synthesis and an unscheduled plant shutdown.

    Working as the actual producer, our relationship with customers doesn’t end at the sale. We field detailed technical questions from industrial and academic labs. A pigment manufacturer wanted a customized particle size distribution for better dispersion — we re-tuned our crystallization protocol, not because it was easy but because we understood his process needed it. Another customer flagged a hydrolysis issue in his final application; our technical team suggested pre-drying his process stream, which solved the problem. This kind of collaboration only comes with full control over production and a willingness to discuss real details, not scripted talking points.

    Specifications and Real-World Implications

    A typical batch leaves our lines at greater than 99% purity, with tight control on water content and trace metals. Wild swings in purity or particle structure disrupt downstream chemistry. Suppliers further down the value chain sometimes gloss over the difference between 98% and 99.5%. From our perspective, that half-percent keeps a dye process clean, allows for more exacting synthesis, and avoids ugly surprises at scale-up.

    Talking “specs” without context misses the point. We’ve watched as some batches outside specification clog automated dispensers or cause unwanted shades in pigments. A few tenths of a percent of an unknown impurity can shut down a pharmaceutical trial. We retain per-batch process data, so end-users can trace any anomaly. Compliance with REACH, K-REACH, and TSCA matters to export markets; our documentation builds trust, but the real assurance comes from our ability to address questions directly, as the producer.

    Oxanilic Acid: Practical Usage in Industry

    Our long-term clients use oxanilic acid in colorant streams, organic synthesis, surfactant modification, and herbicide manufacturing. They look for a solid, free-flowing, white crystalline acid with just the right consistency to dose in precise quantities. Results matter more than product gloss. Customers using less controlled material report sticky residues or mismatched reactivity under standard reaction conditions. That’s not a theoretical risk; we’ve evaluated returned lots from clients frustrated by these challenges after trying lower-priced goods.

    We test our own oxanilic acid for both lab and production scale-up compatibility. For dye and pigment makers, tight color tolerance and solubility parameters shape the ultimate end-use. In herbicides, off-odor or unwanted side reactions create regulatory headaches the user cannot afford. Our technical support staff have remedied agrochemical plants plagued by inconsistent raw material attributes, working side by side to address both formulation and regulatory compliance.

    Comparing Oxanilic Acid to Other Intermediates

    Many confuse oxanilic acid with anilino acetic acid or other similar-sounding intermediates. We’ve found direct product substitutions rarely pan out. Users attempting “drop-in” replacements often run into unexpected downstream consequences, whether from minor solubility differences, melting point drift, or trace contaminants unique to another compound’s synthesis pathway. Our technical staff helps teams model such changes, running comparisons with side-by-side analyses.

    Some customers come to us after disappointing experiences with generic or brokered versions, believing all synthetics are comparable. In practice, the differences reveal themselves under real production pressures. Subtle distinctions in the acid group’s orientation or the presence of specific side-products change reaction kinetics and yield. Dye manufacturers often see color deviations, pigment plants struggle with residue during drying and filtration. These nuances only show up in scale, but they matter most for the daily operations of our buyers.

    Sourcing Direct from the Manufacturer

    The biggest concern for industrial users is not just price, but reliability over the long term. Resellers and distributors might shuffle stock from warehouse to warehouse, losing track of provenance or blend in material from mixed production streams. As the manufacturer, every kilogram originates from our controlled environment. Our technical team fields complicated requests — for instance, customers with novel applications request batch samples for pilot trials, and sometimes invite us onsite for troubleshooting. Being the original producer means we don’t need to wait for permissions from suppliers; we can deliver both the technical explanation and, if needed, a new production run tailored to new requirements.

    We work with multi-year supply agreements, so customers never wonder about batch-to-batch variation. If a customer’s process evolves, our R&D team collaborates directly to update parameters and documentation together. This stability ripples through the supply chain — inventory teams forecast with more confidence, production downtime drops, and operators avoid the confusion of troubleshooting issues that stem from poorly characterized lots.

    Building Trust through Transparency and Knowledge

    As the original producer, we answer questions about synthetic route, impurities, drying, and handling procedures without hesitation. While all raw material suppliers claim transparency, our lab doors are open to customer audits as needed. Since we record and store process data for every lot, technical investigations rely on firsthand evidence. We publish impurity testing data, traceable back to individual raw materials, so chemists know exactly what enters their reactors.

    For clients in the environmental chemistry, dye, and pigment spaces, our track record lets them skip the costly stage of running pilot lines with uncertain input. Environmental groups ask for confirmation about by-product generation; we supply documentation to support full lifecycle analysis. Meeting regulatory authorities for emerging applications, especially food contact materials or active pharma intermediates, gets easier with direct factory-level technical reports. Working as the real manufacturer lets us support this depth — it’s knowledge built day after day on the shop floor, not pieced together from disparate warehouses.

    Addressing Industry Challenges

    The chemical sector frequently faces price fluctuations, raw material shortages, and the risk of unvetted intermediates. We deal with these realities by investing early in supply chain resilience and process optimization. Years of experience show that fast reactions to sourcing difficulties mean stable production for our clients. For oxanilic acid, our procurement team secures multi-year supplies from trusted partners, insulating the factory against volatility seen in spot markets. Down cycles in chemical demand don’t catch us unprepared; our facility runs with redundancy, and our experienced maintenance crew ensures uptime remains high.

    Technical issues sometimes hit even the best-run operations. Process upsets, environmental compliance changes, or shifts in regulatory priorities create real-world challenges. For oxanilic acid, batch-to-batch reproducibility is non-negotiable. Our analytical chemists regularly recalibrate methods, and we participate in inter-lab comparisons with prominent industry partners. Customer feedback loops track not just quality complaints, but also “silent” trends — such as gradual changes in material compatibility or critical impurities. By keeping lines of communication open, and controlling our own production, we maintain a buffer zone against unexpected shifts.

    Real-World Case Studies: Reducing Downtime and Increasing Confidence

    A major pigment manufacturer recently struggled with inconsistent color shades traced back to imported oxanilic acid. After switching to our material, they reported a measurable drop in lot failures and stopped mid-batch adjustments. Their engineers visited our plant, reviewing our particle size analysis and drying techniques. They adapted our protocol recommendations, and now mention improved throughput on their process line during regular technical meetings.

    At a herbicide blending plant, leftover metallic impurities from an externally sourced acid were contaminating product lines. We provided spec-to-spec assurance, digging through their analytical data to compare with ours. After switching, their regulatory reviews sailed through with no flagged deviations.

    Even academic labs benefit. A research group synthesizing novel intermediates observed poor crystallization and erratic yields from aggregator-bought oxanilic acid. After we shared our technical notes and supplied material from a freshly validated lot, their reproducibility jumped. We even invited their graduate students to observe the manufacturing sequence and consult with our analytical team, bridging laboratory curiosity with operational experience.

    Oxanilic Acid in the Broader Chemical Landscape

    Demand for highly stable intermediates only grows. Regulatory requirements tighten, and specification creep makes undifferentiated quality a liability. Today’s manufacturers need a product that performs predictably every shipment, regardless of destination. Supplying oxanilic acid means shouldering that responsibility. Our practice is not to chase the lowest prices but to anchor our production team to tangible value in reliability, technical trust, and practical troubleshooting.

    We see this reflected in the ways our long-term partners operate. They invest less time firefighting input variance and more on developing better processes. The savings from avoided downtime, quicker lead-time fulfilment, and smoother scale-up more than offset what some view as higher initial costs. By focusing on real data, shared process knowledge, and open dialogue, the result is less operational uncertainty and fewer reactive interventions downstream.

    Summary: The Manufacturer’s Perspective

    Oxanilic acid from our facility is not just a commodity. Each shipment embodies years of process discipline, technical refinement, and customer interaction. Direct production control allows us to keep batch quality high and document every deviation before it leaves our walls. Our support staff know the product as makers, not middlemen; this difference reshapes troubleshooting and real-world outcomes. Industries from dye to herbicide to research laboratories rely on hassle-free operations, and we craft oxanilic acid to fit into that expectation — consistently, with focus on the details that only the maker truly knows.