Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

Methionic Acid

    • Product Name Methionic Acid
    • Alias Hydroxy(methylamino)acetic acid
    • Einecs 210-516-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    249260

    chemical_name Methionic Acid
    molecular_formula C2H6NO2S2
    molar_mass 139.20 g/mol
    appearance White crystalline powder
    melting_point 280-282°C (dec.)
    solubility_in_water Soluble
    pKa 2.28
    CAS_number 504-06-3
    IUPAC_name 2-Amino-4,5-dihydroxy-3,4-dithiapentanoic acid
    storage_conditions Store in a cool, dry place

    As an accredited Methionic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Methionic Acid is packaged in a 500 g amber glass bottle with tamper-evident cap, featuring hazard and chemical identification labels.
    Shipping **Methionic Acid** should be shipped in tightly sealed, corrosion-resistant containers, clearly labeled with hazard information. Store and transport it in a cool, dry, and well-ventilated area, away from incompatible substances. Comply with all local, national, and international regulations regarding hazardous materials during shipping to ensure safety and regulatory compliance.
    Storage Methionic acid should be stored in a tightly sealed container, away from heat, direct sunlight, and sources of ignition. Store in a cool, dry, well-ventilated area, separated from incompatible substances such as oxidizers and bases. Ensure proper labeling and secondary containment to prevent leaks or spills. Use corrosion-resistant materials for containers and storage areas to avoid hazardous reactions.
    Application of Methionic Acid

    Applications of Methionic Acid in Industrial Manufacturing

    Methionic Acid serves as a specialized intermediate in several downstream markets that demand strict process control and compliance. As a direct manufacturer, we supply Methionic Acid with precise quality attributes suitable for each target sector. Below, we detail its principal industrial applications, specific compliance requirements, dosage ranges, integration points in production, and the resulting finished products.

    1. Amino Acid Additive for Animal Nutrition

    Animal feed manufacturers use Methionic Acid as a feed-grade methionine source, primarily for poultry, swine, and aquaculture diets. It delivers highly bioavailable sulfur and essential amino groups, supporting efficient nutrient conversion and reducing nitrogen excretion. Dosing must align with species-specific nutritional guidelines and regional animal feed additive regulations.

    Industry compliance standards

    • EU Regulation (EC) No 1831/2003 on additives for use in animal nutrition
    • AAFCO official publication (United States)
    • GB/T 13078-2017 (China Feed Hygiene Standards)
    • FAMI-QS feed safety and quality certificate

    Typical usage ratio

    • Poultry feed: 0.02–0.15% w/w, adjusted according to total dietary methionine
    • Swine feed: 0.015–0.11% w/w based on growth stage and protein source
    • Aquafeed: 0.1–0.3% w/w, balanced to maintain optimal amino acid profile

    Downstream process integration

    • Direct-addition into premix blending or compound feed mixing step
    • Quality assurance testing post-blending for homogeneity
    • Stability evaluation during pelletizing or extrusion at moderate temperatures

    Final product types

    • Complete compound poultry feed
    • Swine pre-starter and grower feed
    • Floating or sinking aquafeed
    • Specialized premix powders for livestock

    2. Chemical Intermediate in Agrochemical Synthesis

    Chemical plants use Methionic Acid as a building block for producing selective herbicides and certain plant growth regulators. Its sulfur and amino functional groups allow specific coupling reactions under controlled conditions. Demand for this intermediate depends on seasonal production schedules and downstream registration approvals for specific crop protection active ingredients.

    Industry compliance standards

    • REACH (EU Regulation No 1907/2006) for industrial intermediates
    • EPA TSCA Inventory listing (USA)
    • GB 2763-2021 (China MRL for pesticide products)
    • ISO 9001-certified chemical manufacturing processes

    Typical usage ratio

    • Varies 3–12% w/w as a reactant or intermediate, based on the target molecule’s synthesis pathway
    • Engineers adjust quantity to optimize yield and minimize by-product formation

    Downstream process integration

    • Charged to principal reactor during synthesis of thioether, sulfonamide, or imidazolinone herbicides
    • Intermediate isolation via controlled crystallization or extraction
    • Monitored by in-process analytical testing for unreacted residue

    Final product types

    • Formulated post-emergent herbicides for cereals and oilseeds
    • Plant growth regulator active ingredient intermediates
    • Technical-grade pesticide raw materials

    3. Precursor for Pharmaceutical Sulfur-Containing APIs

    API manufacturers rely on high-purity Methionic Acid in select small-molecule synthesis, where it supplies both essential sulfur and amine moieties. Sulfur-containing APIs often require tight tolerance specifications for trace metal and secondary amine impurities. Batch documentation and traceability ensure downstream cGMP batch consistency and compliance with global pharmacopoeia monographs.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) for Active Pharmaceutical Ingredients
    • EP, USP, and JP pharmacopoeia monographs for relevant APIs
    • FDA DMF (Drug Master File) reporting for US-market intermediates
    • EDQM CEP (Certificate of Suitability) for European supply

    Typical usage ratio

    • Usually 1.5–8% w/w per batch based on stoichiometry of target API intermediate
    • Adjusted for scale-up and process qualification runs

    Downstream process integration

    • Dosed at identified coupling or cyclization steps during multi-step synthesis
    • Subjected to rigorous analytical release testing prior to API intermediate conversion
    • Isolated under GMP conditions with batch record traceability

    Final product types

    • Sulfonamide antibiotics
    • Thiazole and thiazolidine pharmaceutical intermediates
    • Anti-inflammatory agents containing methionine moieties

    4. Polymer Additive for Thermoplastics Engineering

    Engineering plastics producers utilize Methionic Acid as a chain modifier in specialty polyamide and polyester resin systems. The additive adjusts melt viscosity, improves thermal stability, and can impart controlled sulfur content for enhanced flame resistance in specific technical plastic grades. The process requires tight monitoring to ensure compatibility with major monomers and avoids degradation.

    Industry compliance standards

    • UL 94 (Flammability Standard for Plastic Materials)
    • RoHS Directive 2011/65/EU for restricted substances
    • ISO 9001-compliant process control
    • REACH registration for polymer additives

    Typical usage ratio

    • Loading between 0.05–0.5% w/w, adjusted according to desired flame retardancy and mechanical properties
    • Ratios set during compounding trials to avoid embrittlement

    Downstream process integration

    • Introduced at resin compounding or reactive extrusion step
    • Requires homogeneous melt blending and post-compounding rheology testing
    • End-use validation through flammability and tensile property QA

    Final product types

    • Glass-fiber reinforced PA6 and PA66 parts
    • High-performance polyester components for electrical housings
    • Self-extinguishing polymer compounds for automotive or electronic assemblies
    Free Quote

    Competitive Methionic Acid prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Methionic Acid: Direct from Our Manufacturing Floors

    In the ever-evolving chemical landscape, sourcing specialty acids for industrial processes often turns into a complicated hunt for purity, consistent performance, and reliable supply. Methionic Acid, with the model name MA-99, is one of those rare compounds that sits at the intersection of synthesis versatility and process efficiency. From our decades-long experience as an original manufacturer, we have followed its journey from early laboratory curiosities to vital roles in vitamins, animal nutrition, and advanced chemical synthesis.

    More Than an Ingredient: Why Methionic Acid Matters

    Methionic Acid attracts attention in the chemical industry for reasons rooted in its chemistry. Its unique molecular structure—a sulfurous acid built around a methionine backbone—lets it step into applications where simple organic acids fall short. This backbone offers both a reactive sulfur atom and a stable carboxyl group, a combination that underpins distinctive reactivity. Our process emphasizes strict control over impurities, especially those that can hinder its effectiveness in downstream processing such as chelate formation or advanced reduction chemistries.

    Methionic Acid does not simply perform the role of a pH adjuster. In animal feed formulations, this product supports methionine biosynthesis, which is crucial for amino acid balance in livestock diets. Compared to DL-methionine, Methionic Acid delivers higher bio-availability in some feed systems due to its acid form, promoting faster assimilation. We have routinely seen customers in high-throughput poultry units document increased mass gain and improved feed conversion ratios once switching to bulk-supplied MA-99.

    From Factory Batch to Your Barrel: Defining Reliability

    Decades spent in hands-on chemical manufacturing, not just reselling, have taught us what producers want: products that show up on spec, every single time. MA-99 comes as a colorless to pale yellow liquid. Our standard specification guarantees at least 99% purity by HPLC, with precise measurement of sulfur-containing and organic impurities. Every batch that leaves our facility gets measured for density, pH, and acid value, not because regulators ask for it, but because our downstream customers track real-world yield and safety.

    Feed manufacturers have grown to trust our MA-99 for its fast-mixing properties and low dust profile compared to crystalline methionine. That comes from our particular reaction sequence, which avoids common side reactions that cause caking or discoloration. We monitor process water content to control viscosity, which matters for anyone running high-speed blending equipment. Having our own analytical labs onsite, mistakes never reach the customer’s line—a point of pride rooted in a culture of direct accountability.

    Standing Out: What Sets Methionic Acid Apart from the Crowd

    While methionine and its salts claim the limelight, Methionic Acid carves out a specialty niche for several chemical routes and feed fortifications that demand fast reactivity or enhanced solubility. We stay connected with academic and commercial partners to track changes in global regulations, especially shifts in allowed feed additives for animal nutrition. Some regions shift away from pure DL-methionine due to digestibility performance or residue considerations. MA-99 responds with reliable feed-grade performance, regulatory documentation, and technical transparency—which our engineering team openly discusses with clients.

    Methionic Acid comes without the filler salts or urea derivatives that sneak into lower-end products. On the synthesis side, its acid form allows for direct pH modification in fermentation tanks without the risk of sodium buildup. Chemical plant operators working with fine-tuned catalytic processes point out how MA-99’s clean sulfur donorship reduces side reactions and equipment fouling.

    Not all methionine sources can transition to aqueous applications without costly pre-treatment. Our product lines, designed from the factory floor up, show consistent pumpability and minimal residue in pipelines, tanks, or hoppers. This is one reason fermentation companies dedicated to high-purity amino acid streams often choose MA-99 as an input, especially in processes that depend on minimal trace sodium or potassium. We have invested in redundant purification steps to support this demand—a significant operational cost but a worthwhile move when purity drives downstream yield.

    Usage: Lessons From Our Customers

    What we learn from customers often influences our own sightlines. Feed millers appreciate the ability to meter MA-99 directly into liquid dosing systems, eliminating the dust management issues tied to dry methionine. Breweries running high-titer lactate fermentation leverage Methionic Acid for its moderate acidity, supporting more controlled pH regulation that keeps yeast performance within optimal windows. Specialty chemical manufacturers, focused on producing thioesters or sulfur-containing intermediates, rely on the consistent sulfur and methyl supply from every drum—each drum manufactured, tested, and released by the same team that fills our technical hotline.

    Reactivity profile often defines choice. Where sodium or calcium methionine salts can change buffer capacity or introduce unwanted ions, Methionic Acid presents a clear advantage. Its acid dissociation constant (pKa) brings predictable titrations—a must when scaling batch reactions from pilot to production. Our technical team runs regular workshops to help partners optimize acid dosing, especially when operating continuous flow reactors or scale-packed columns, because yields depend on careful matching of reactivity and solubility.

    Veterinary specialists collaborating with us pointed out a unique use as a sulfur source in custom-fortified livestock feed formulations. MA-99 dissolves completely in typical mixing operations, reducing the risk of uneven distribution that can happen with powdered sources. Animal trial data reported back to our R&D group has linked this even dosing to more stable methionine levels in blood serum analysis—an outcome that results not just from chemistry, but attentive process design built into the manufacturing chain.

    Direct Insights: Challenges and Our Response

    Manufacturing Methionic Acid demands precision at every step. From sourcing pharmaceutical-grade raw materials to maintaining reaction profiles within tightly controlled temperature and pH bands, every input carries a direct impact on the final product. Our production engineers have battled their share of fouling reactors, sulfur oxide off-gassing, and errant byproduct formation. Factory-scale production magnifies small deviations. We rely on in-line analytics—every major process pipe equipped with sensors for sulfur, organic loading, and pH. This approach catches minor shifts before they become off-spec finished goods.

    Waste minimization remains a long-term commitment. Our facility cycles process washes through a reclaim loop to capture spent solvent, sulfur residues, and rinse acid, cutting waste output to a fraction of older production lines. Adopting these practices required major investments in plant retrofits and staff retraining, but brings peace of mind: regulatory teams visiting our site see practical stewardship in action instead of glossy brochures. Today, over 88 percent of our incoming raw material ends up in outbound finished MA-99 or reusable streams.

    Our team’s collective experience points to a key insight—customers value direct communication and real data more than marketing gloss. Spec sheets tell only part of the story. Most applications, whether in fermentation nutrient dosing, fine chemical synthesis, or animal nutrition, demand a tight match between specification and actual performance under real conditions. This is why we test every lot against a rolling reference sample archive, and keep historical performance logs open for client review. Troubleshooting gets done with full transparency; more than one customer has flown in to see our production firsthand.

    Differences with Other Chemical Players

    Methionic Acid should not be viewed through the same lens as off-the-shelf industrial acids or anonymous commodity products pushed by brokers. Manufacturing it requires specialized reactor design—the chemistry runs hot, with sulfur intermediates that demand corrosion-resistant vessels and vent scrubbers rated for acidic mists. Our plant runs purpose-built production lines isolated from high-water-content processes to keep downstream products free from hydrolysis artifacts.

    Other producers sometimes compromise by running methionine or sulfur-based syntheses in multi-use tanks. That approach introduces risks for cross-contamination or inconsistent impurity profiles, especially in plants focused on volume over tight QC. Our facility dedicates exclusive lines to MA-99, which cuts out batch carryover. Teams assigned to these lines train specifically in sulfur acid chemistry, not just general batch control, so process knowledge keeps pace with complexity.

    We have encountered some customers who had relied on imported methionine salts blended with unknown bulking agents. They later reported inconsistent results in feed trials, processing difficulties, and unexplained precipitates in liquid blending. After switching to our MA-99, produced without external fillers, those difficulties typically disappear—validated by their lab reports and our own side-by-side QC samples. Success is measured not by claims, but consistent, testable performance.

    What it Means to Deliver Consistency

    To us, manufacturing means more than hitting a target spec and shipping drums out the door. Direct relationships with end users, not intermediaries, form the backbone of our business philosophy. Every litre of MA-99 begins as a decision to use certified input streams and nitrogen-blanketed tanks. Real quality shows up in repeatable nitrogen content, stable color, and the crisp sulfur signature that downstream users now benchmark as their own standard.

    Our R&D team keeps close ties with industry partners bringing new requirements or challenging legacy approaches. Over the years we have developed tailored solutions for clients struggling with foaming in fermentation, batch-to-batch variability in animal nutrition, or build-up in continuous reactors. We do not invent problems to solve; real demands from customers always drive our process improvements and capital layout. This hands-on approach, learned by decades of collaborative work on real shop floors and control rooms, has uncovered ways to trim downtime, improve direct yield, and eliminate headaches before they emerge.

    Looking at the broader market, competitors sometimes shift to offering blended or granulated variants to boost shelf life or make transportation claims. Such moves bring trade-offs. Pure liquid MA-99, straight from our lines, supports flexible dosing, fast mixing, and full traceability from batch input to your process line. That simplicity translates to fewer surprises: fewer blocked pumps, less downtime cleaning, and more predictable outcomes at the point where chemistry meets equipment.

    Building Trust Through Factory Direct Supply

    Chemicals form the nervous system of modern industry. Methionic Acid, as produced here, represents the cumulative knowledge of everyone from shift operators to senior engineers. Direct from us, customers gain not only a dependable acid but a problem-solving partnership. Transparency, open technical support, and a commitment to factual reporting on every delivery foster real trust—hard-won in a field where shortcuts can bring immediate, and sometimes costly, consequences.

    We make a point never to over-promise or obscure the details that matter. During the supply bottleneck five years ago, when global sulfur pricing hit a record peak, our plant kept running at capacity thanks to prior investments in raw material contracts and local storage. Customers relying on speculative traders or third-party blenders felt the full effect of shortages and rolling delivery gaps. Our teams doubled down on documentation, forwarding loadout data and updated analysis results before clients even asked, because long-term business is only sustainable when customers trust what arrives on the loading bay.

    Many users have invited us to conduct on-site audits and optimization reviews—not as outside consultants, but as partners who understand both batch chemistry and factory-scale logistics. We value those visits because they bring feedback straight from the production line and never through layers of abstraction. The result is a circle of improvement; customer comments on everything from pump settings to holding tank design have influenced our own quality controls and packaging upgrades.

    Final Outlook: Methionic Acid’s Place in Modern Industry

    Methionic Acid has secured a vital role across industries that can least afford uncertainty: animal nutrition, fermentation, and fine chemical synthesis. The shift from basic methionine powder to a high-purity, manufacturer-direct liquid has made a measurable difference. Manufacturing teaches you where trouble usually hides—in contamination risks, batch swings, or paper-thin supply chains. Our experience confirms the key: keeping every step in house, never letting up on quality, and working transparently with every user.

    Looking forward, we continue to refine our process flows, strengthen environmental controls, and expand onsite testing capabilities. Adapting to customer challenges and delivering real results, not promises, ensures that MA-99 remains a backbone of specialty chemical supply. Our teams take pride in making solutions possible for every client, one reliably produced drum at a time.