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Methanimine

    • Product Name Methanimine
    • Alias formaldimine
    • Einecs 207-898-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    161024

    ChemicalName Methanimine
    MolecularFormula CH2NH
    MolarMass 29.04 g/mol
    CASNumber 2054-29-3
    Appearance Colorless gas
    Density 0.776 g/L (at 25°C and 1 atm)
    MeltingPoint -90 °C (estimated)
    BoilingPoint -64 °C (estimated)
    SolubilityInWater Moderately soluble
    IUPACName Methanimine
    Structure H2C=NH
    PubChemCID 123122
    SMILES C=NH

    As an accredited Methanimine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Methanimine is supplied in a 250 mL amber glass bottle, tightly sealed, with hazard labeling and proper ventilation instructions displayed prominently.
    Shipping Methanimine should be shipped in tightly sealed containers under an inert atmosphere, such as nitrogen, to prevent polymerization and decomposition. It must be handled as a hazardous material, with proper labeling, and shipped according to relevant regulations. Transport in cool, well-ventilated conditions, away from heat, moisture, and oxidizing agents.
    Storage Methanimine should be stored in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances like oxidizers and strong acids. Use tightly sealed containers, preferably under inert gas such as nitrogen, to prevent moisture absorption and polymerization. Properly label storage containers and ensure they are kept at low temperatures to minimize decomposition and maintain chemical stability.
    Application of Methanimine

    Applications of Methanimine in Industrial Manufacturing

    Methanimine, a vital nitrogen-containing intermediate, plays a critical functional role in several industrial chemical processes. As a direct manufacturer, we support downstream production with consistent quality and supply, enabling our partners to achieve precise formulation targets and compliance with demanding operational requirements. Below are the verified industrial application scenarios backed by sector standards and concrete process information.

    1. Agrochemical Intermediate Synthesis

    In the agrochemical manufacturing sector, producers utilize methanimine as a key building block for synthesizing specific herbicide and fungicide actives, particularly those based on triazine and other nitrogen-rich heterocycles. This raw material supports dedicated multi-step synthetic sequences where introducing an imine group is required for constructing ring systems central to agriproducts. Process integration focuses on in-situ generation and immediate downstream reactions to maximize yield and reduce secondary impurity formation, directly influencing the performance and regulatory compliance of the final agrochemical product.

    Industry compliance standards

    • FAO/WHO Specifications for Agricultural Pesticides
    • REACH Registration (EC 1907/2006) for chemical intermediates
    • ISO 9001:2015 for process management
    • China GB/T 1605-2006 (Pesticide Technical Material Quality Standards)

    Typical usage ratio

    • Adjusted between 0.3 molar equivalents to 1.2 molar equivalents per batch depending on the target ring structure and impurity control demands

    Downstream process integration

    • Introduced during the condensation step with cyanuric acid or ketone precursors in closed-loop reactor systems
    • Utilized under controlled pH conditions to facilitate selective imination and downstream cyclization

    Final product types

    • Selective triazine herbicides (e.g., atrazine, simazine intermediates)
    • Fungicide active ingredients with heterocyclic cores
    • Custom agrochemical intermediates for contract synthesis

    2. Pharmaceutical API Synthesis (Antiviral Drug Intermediates)

    Methanimine serves as a practical imine nitrogen donor in the multi-stage synthesis of certain antiviral active pharmaceutical ingredients (APIs) where precise functional group installation is mandated by process chemistry. Manufacturers rely on its controlled reactivity to introduce imino moieties during scaffold elaboration, maximizing purity and minimizing downstream rework or purification costs. Strict adherence to pharmaceutical-grade controls and documentation is essential to ensure regulatory acceptance and lot traceability for use in human health applications.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • United States Pharmacopeia (USP) for ingredient handling
    • European Pharmacopoeia reference procedures
    • FDA 21 CFR Part 210/211 (cGMPs for Drugs)

    Typical usage ratio

    • Varies from 0.05 to 0.25 equivalents relative to the precursor in batch syntheses, controlled by reaction pathway to avoid side product formation

    Downstream process integration

    • Dosed in solution-phase amidation or imination steps under nitrogen blanketing
    • Reacts with aldehyde- or ketone-functionalized scaffolds in mid-stage API routes

    Final product types

    • Nucleoside/nucleotide antiviral APIs (e.g., remdesivir intermediates)
    • Pyrimidine- and triazine-based therapeutic agents
    • Pharma-grade fine chemicals for contract manufacturing

    3. Industrial Gas Treatment and Flue Gas Purification

    Methanimine is adopted as a key intermediate in the synthesis of specialty amines used for acid gas scrubbing systems, especially in upgrading or custom blending amine absorbents for CO₂, H₂S, and NOx capture in energy and petrochemical processes. Its reactivity profile supports formation of tailored amine agents required by facility-specific emission control mandates, and batch reproducibility directly impacts removal efficiency and permit compliance in downstream gas treatment operations.

    Industry compliance standards

    • US EPA Clean Air Act (CAA) regulations for hazardous air pollutant removal
    • EN 14181 (Quality Assurance of Automated Measuring Systems, EU)
    • API Standard 941 for amine system integrity management
    • ISO 14001:2015 for environmental management systems

    Typical usage ratio

    • Employed at 10-20% of total amine formulation mass on a dry basis, depending on targeted acid gas loading and process configuration

    Downstream process integration

    • Reacted with primary amines or polyols to generate proprietary gas scrubbing agents in batch or continuous synthesis reactors
    • Fed directly into on-site blending units or toll compounding lines

    Final product types

    • Selective and tailored amine absorbents (for CO₂, H₂S, NOx removal)
    • Industrial flue gas purification blends
    • Gas treatment consumables for refinery and power plants

    4. Resin and Polymer Modifier Production

    Manufacturers use methanimine in the modification of phenolic and amino resins, where it introduces reactive imino groups that enhance crosslinking properties and compatibility with reinforcing materials. This approach is particularly favored in the fabrication of advanced composites and adhesives intended for high-performance applications, such as electrical insulation, industrial coatings, and engineered wood products. The performance yield and downstream curing profile must meet both chemical and physical certification regimes to satisfy the value chain quality needs.

    Industry compliance standards

    • ASTM D1610 (Standard Specification for Phenolic Resins)
    • UL 94 Flammability Standard for polymeric materials
    • RoHS Directive 2011/65/EU (for electrical applications)
    • ISO 9001:2015 documented process controls

    Typical usage ratio

    • Optimized within 0.5–2.0% by weight of total resin mass, based on targeted glass transition temperature and end-use stress resistance

    Downstream process integration

    • Added post-polycondensation during resin modification
    • Subjected to in-process QC to verify imine incorporation and batch homogeneity

    Final product types

    • Modified phenolic resins for circuit boards and insulation panels
    • High-bond adhesives used in engineered timber
    • Composite pre-pregs for structural and automotive applications
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    Certification & Compliance
    More Introduction

    Methanimine: Our Approach and Experience With a Unique Building Block

    Understanding Methanimine—A Building Block Rooted in Experience

    Methanimine stands out in the family of simple organic compounds, not only for its structure but also for the practical challenges and solutions that come with its manufacture and use. Over the years, we’ve taken a hands-on approach from the reactor floor to the storage facility, recognizing the potential of truly basic molecules like methanimine, CH2NH. We meet every batch with more than standard protocol; here, raw material quality, catalytic path, temperature, and containment aren’t abstract factors—they’re everyday realities. This direct experience shapes both product and process.

    Physical and Chemical Specifics—Why Details Matter

    Methanimine belongs to the imine family, essentially the nitrogen analog of formaldehyde. Its molecular weight, volatility, and reactivity make it an unusual presence in the lineup of reactive intermediates. As a gas at room temperature, methanimine responds sharply to changes in pressure and temperature. This aspect dictates not only plant layout but also the way we contain and move the material. Even a minor lapse in pressure control can lead to losses or additional hazards, so we’ve built systems that adjust automatically and allow operators to intervene early.

    The grade and purity of our methanimine matter just as much as its physical state. Impurities, especially water or oxidants, alter its behavior in downstream reactions. We route all streams through carefully selected adsorbents and keep the production environment dry and oxygen-free. This minimizes byproducts, leaving methanimine in the form we promise—useful, reactive, and reliable.

    Pushing Technical Boundaries—Production Experience That Counts

    Unlike many chemicals, methanimine doesn’t come with the luxury of easy storage or transport. As a manufacturer, we don’t just assemble what’s on a formula sheet. Our engineers have refined both batch and continuous processes, often pushing equipment design to its limits. Using methanol or other precursors, and employing specialized catalysts, we manage process conditions in a carefully balanced sequence.

    There’s no room for error. Overshooting temperature or letting trace air slip in might lead to runaway polymerization or side reactions. These real-world concerns have forced our team to rethink process safety at nearly every step. Safety systems get tested, component materials get reviewed for slow degradation, and maintenance routines aren’t left as an afterthought. Success means years without incident, not just a compliant audit report.

    Usage—Meeting Specific Demands in Industry and Research

    Methanimine’s reactivity makes it a favorite for synthetic chemists and industrial producers working at the edge of innovation. The molecule acts as a precursor to various specialty amines and heterocycles, particularly in pharmaceutical and agrochemical routes. Where conventional aldehydes or amines lag, methanimine adds a sharper, more selective path. Its ability to introduce C=N functionality cleanly proves essential for building both simple and advanced molecules.

    In resin manufacturing, methanimine takes part as a crosslinker, reaching into areas untouched by other simple imines or aldehydes. For these clients, batch-to-batch uniformity doesn’t just save time—it protects expensive downstream chemistry from spoilage. Our consistency translates to predictable outcomes and minimal headaches for operators managing multi-day reaction runs.

    Academic labs often call for custom volumes as small as a few tens of grams, while large-scale industrial clients expect a steady flow at consistent pressure and purity. That flexibility isn’t theoretical; it grows from years tracking nitrogen and carbon throughout diverse production schedules, matching output to need rather than pushing one-size-fits-all quantities.

    Real-World Differences from Other Products

    Some think of methanimine as simply another member of the imine group. Our experience says otherwise. In production, its volatility and sensitivity separate it sharply from more familiar analogues like acetaldehyde or even methylamine. Equipment designed for those materials doesn’t always translate. Methanimine interacts unpredictably with common metals, requiring careful selection of containment and transfer lines. Small leaks or minor design shortcuts quickly turn into operational headaches—sometimes weeks after an installation.

    The simplicity of the molecule hides a layered complexity in both synthesis and downstream transformation. Compare it to methylamine: methylamine can be stored more easily in aqueous solution or pressure cylinder, handled through established supply chains. Methanimine resists this treatment. Only longstanding relationships with logistics providers who know the challenges can keep the supply chain from breaking down.

    Products like formaldehyde bring a set of hazards and requirements, but the way methanimine responds to temperature, pressure, and light is even less forgiving. Experience with one does not guarantee a smooth relationship with the other. We adapt plant-wide procedures, from scale-out plans to emergency response, because legacy protocols written for different compounds miss subtle behaviors unique to methanimine. Much of the learning happens through careful observation, regular review, and not repeating mistakes remembered from prior campaigns.

    Challenges and Solutions in Daily Handling

    Methanimine doesn’t allow shortcuts in handling, so we adopt practices that go deeper than regulatory minimums. Sealing joints, inspecting valve seats, and calculating thermal loads might sound routine, but with this product, even a minor error multiplies. During transfer, operators monitor both system integrity and real-time process analytics. Relying on experience, not just standard operating procedures, keeps everyone alert to the signs of drift or an early-stage leak.

    Alternative storage strategies might promise greater stability. We’ve tested auxiliary scavengers and designed buffered storage systems that postpone polymerization and limit emissions, all while keeping the active material on-hand for immediate use. Each approach gets reviewed and improved, drawing from long conversations with front-line staff who know exactly what can go wrong—and how to catch it early.

    Supporting Innovation, Not Just Supply

    Our work with methanimine doesn’t end with shipment. Teams support partners by sharing operational stories, design tweaks, and lessons learned from incidents that never reached public notice. Startups exploring electric-field catalysis or new imine-derived monomers approach us for more than commodity supply—they want the wisdom that comes from seasons of hands-on trial and error. Some customers bring new reaction schemes that push boundaries, and we help by adjusting specification targets, offering advice on alternative purification paths, or modifying packaging to fit new test rigs.

    This shared learning benefits the entire ecosystem. Synthetic routes and applications shift every year, but a central thread runs through all progress: the people closest to the reactor and tanker, spotting issues before they escalate and building extra capacity for the unexpected. Real innovation requires this nerve center, and as a manufacturer, we are committed to growing it.

    Managing Risk—Realities No Handbook Covers

    Methanimine production and handling invite hazards most lab texts barely mention. Polymerization risk hovers over every tank and transfer. Each new hire learns firsthand the difference between a pipedream protocol and the demands of real-world chemistry. Regular training, performance reviews, and technical cross-checks aren’t just paperwork—they’re defenses built from old stories and near-misses.

    Regulatory compliance serves as a floor, not a ceiling. Our systems follow local and international requirements, but extra layers come from walking the plant, reviewing incident logs, and asking uncomfortable questions about “what if.” Environmental containment, emergency shutdowns, air quality monitoring, and regular equipment upgrades have become part of daily routine. Customers and neighbors depend on us to exceed bare minimums every day, not just during inspections.

    Working With Customers—Collaboration In Practice

    Our partnerships grow from direct and continuous dialogue. No product stays unchanged; especially one as peculiar as methanimine. Lab-scale customers push for tighter specification margins, while industrial buyers want delivery formats that fit specialized equipment. We respond to feedback by adjusting process parameters, modifying delivery vessels, and introducing new analytical checkpoints. Dedicated technical liaisons keep dialogue open, investigate root causes of rejects, and help introduce new protocols based on field results rather than assumptions.

    Sometimes, even product complaints open doors to new improvements. If a partner faces an inconsistent yield or reacts to trace impurity profiles, we run parallel tests and share raw data. This openness doesn’t just fix problems one batch at a time—it identifies broader process changes that ripple across all operations.

    Insights From Scale-Up and Scale-Down

    Methanimine shows different faces at small and large volumes. On laboratory scale, the key issue usually lies in producing just enough without losing critical reactivity. Experimental apparatus with variable pressure control and quick-quench options often suit the role. On industrial lines, the story takes a new turn—risk balancing and quality tracking overshadow every step. We invest in modular skids and real-time analytical feedback to bridge the scale divide, allowing us to deliver consistent batches whether making a few liters or thousands of kilos.

    This scaling flexibility proves especially important for pilot plants and research partnerships, where both volume and timing fluctuate. Our experience dealing with raw material fluctuations, logistical hiccups, and sudden demand spikes has shaped a lesson: building redundancies and contingencies into every workflow, because methanimine never gives room for complacency.

    Environmental Impact—Sustainable Practice Born From Necessity

    Methanimine’s high reactivity brings environmental challenges as well as opportunities. Vent and fugitive emissions matter to us, so we’ve devoted significant resources to closed-loop handling and real-time emission capture. Over time, our efforts have shifted from end-of-pipe solutions to process-integrated containment, where leaks are detected and corrected before emissions leave the plant floor.

    Process optimization ties closely to environmental responsibility. Incremental upgrades—tighter gaskets, improved thermal management, and high-efficiency purification columns—lower waste and increase yield. Each modification is tracked in sustainability logs, and lessons feed back into both operations and customer support.

    We routinely invite external audits and share lessons with peers, knowing that pressure to improve never truly ends. This habit of openness and correction means methanimine supply chains under our care set a high bar for both performance and responsibility.

    Technical Support and Future Outlook

    Methanimine features in several future-facing research lines: new materials, renewable feedstock integration, and advanced pharmaceutical intermediates. Our teams spend time reading journals, visiting customer sites, and testing emerging technologies not yet ready for large-scale production. When partners return with new application ideas or patent literature, we often step into joint trials, adjusting operational variables to test outcomes at scale.

    This feedback loop shapes both our product and service roadmap. New requests lead to modifications in drying technology, automation, and trace analysis. Sometimes, today’s customer problem surfaces tomorrow’s market trend, setting the stage for a new wave of applications. As the field grows, we expect methanimine’s role to shift—from niche to staple in select chemistries—driven by both technical innovation and the lessons learned from working alongside persistent, hands-on teams.

    We value every conversation with researchers and industrial partners, knowing that trust and shared outcomes build a foundation stronger than any technical specification. With each new campaign, we stay close to the chemistry and the customers, setting standards for safety, reliability, and progress in the real world of methanimine manufacturing.