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Metalaxyl-m

    • Product Name Metalaxyl-m
    • Alias Mefenoxam
    • Einecs EINECS 256-145-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    669161

    common_name Metalaxyl-m
    chemical_name Methyl N-(methoxyacetyl)-N-(2,6-xylyl)-DL-alaninate
    synonyms Mefenoxam, Metalaxyl-M
    cas_number 70630-17-0
    molecular_formula C15H21NO4
    molecular_weight 279.33 g/mol
    physical_state Solid (crystalline powder)
    color White to pale yellow
    melting_point 71–72°C
    solubility_in_water 26 g/L (20°C)
    mode_of_action Systemic fungicide
    main_usage Control of oomycete fungi (e.g., downy mildew, Pythium spp.)
    toxicity_class Class III (slightly hazardous)
    stability Stable under normal conditions
    application_methods Seed treatment, foliar spray, soil drenching

    As an accredited Metalaxyl-m factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The Metalaxyl-m packaging is a sturdy, white 1-liter plastic bottle with a secure cap, labeled with hazard symbols and product information.
    Shipping Metalaxyl-m should be shipped in tightly sealed, labeled containers, protected from moisture and direct sunlight. Transport in accordance with local regulations for hazardous chemicals. Avoid extreme temperatures. Ensure containers are upright and secure during transit. Use protective packaging to prevent leaks or spills, and include proper hazard warnings on all shipping documents.
    Storage Metalaxyl-m should be stored in its original, tightly closed container in a cool, dry, well-ventilated area, away from direct sunlight and sources of heat or ignition. Keep it separate from food, animal feed, and incompatible materials. Store at temperatures between 0°C and 40°C, and ensure the area is secure, clearly labeled, and inaccessible to unauthorized personnel, children, and animals.
    Application of Metalaxyl-m

    Applications of Metalaxyl-m in Industrial Manufacturing

    As a specialist producer of Metalaxyl-m, we supply formulation-grade material to leading industrial partners focused on advanced crop protection. Below, we detail sector-specific applications, process integration points, required compliance standards, working concentrations, and typical finished products for Metalaxyl-m in professional manufacturing environments.

    1. Agricultural Fungicide Formulation for Seed Treatment

    Metalaxyl-m serves as an essential active for industrial seed treatment formulators targeting oomycete disease control in high-value crops such as maize, cereals, and oilseeds. Manufacturers typically apply slurry or film-coat processing using automated batch blending. Strict stewardship protocols control worker exposure and environmental emissions during formulation. Downstream, treated seeds undergo mandatory residue analysis before market release to comply with international export requirements. Only registered, audited facilities incorporate Metalaxyl-m in ready-to-use seed treatment lines.

    Industry compliance standards

    • EU Regulation (EC) No 1107/2009 on plant protection products
    • US EPA PRIA standards for seed treatments
    • OECD GLP and ISO 9001:2015 QMS for pesticide formulation
    • FAO/WHO Maximum Residue Limits (MRLs) for treated seeds

    Typical usage ratio

    • 0.1–0.5% w/w based on active content relative to seed mass, adjustable per crop variety, target pathogen, and seed size

    Downstream process integration

    • Added during aqueous or solvent-based mixing prior to film application or pellet coating
    • Participates in co-formulation with colorants, binders, and flow agents
    • Monitored by HPLC during in-process QC to verify uniform loading
    • Final packaged seeds pass two-stage laboratory residue screening

    Final product types

    • Treated maize, wheat, sunflower, and rapeseed seeds
    • Dosed hybrid and parental lines for certified seed distributors

    2. Commercial Crop Protection Suspension Concentrate Production

    Major crop protection manufacturers incorporate Metalaxyl-m into high-volume suspension concentrates (SC) focused on foliar use in potato, tobacco, grapevine, and other high-value crops susceptible to downy mildew and phytophthora. SC lines employ high-shear dispersion, multi-stage homogenization, and standardized particle sizing protocols for shelf stability. Formulators precisely meter Metalaxyl-m and test each batch for active content, dispersibility, and agrochemical compatibility. Finished SCs support farmer application by boom sprayer following strict label rates and re-entry intervals.

    Industry compliance standards

    • ISO 9001:2015 and 14001 for agrochemical manufacturing
    • China GB 2763 for pesticide MRLs
    • Brazil ANVISA pesticide registration guidelines
    • JAPAN N-Pesticide Law for import/export

    Typical usage ratio

    • 5–8% w/w active material in SC bulk concentrate, adjusted for desired dilution rates and field application targets

    Downstream process integration

    • Wet-milled with surfactants and anti-settling agents during concentrate preparation
    • Formulated post-synthesis with micronization for improved bioavailability
    • QC checks include viscosity, particle analysis, and chemical stability
    • Packaged as liquid concentrate for commercial distribution

    Final product types

    • 250 g/L or 480 g/L Metalaxyl-m SC for field application
    • Private-label and branded agrochemical SCs for regional distributors

    3. Granular Fertilizer Coating for Nursery and Horticulture

    Professional horticulture solution providers use Metalaxyl-m for protective coating of slow-release granules applied in nursery and floriculture. Automated drum coaters or fluidized-bed granulators add the active in a polymeric carrier to control leaching in soilless cultivation and greenhouse environments. Every production batch undergoes retention and release performance trials to avoid root zone off-target movement. Only pre-approved carriers and polymers are permitted based on biodegradability and crop safety validations. Compliance with target crop residue regulations is mandatory.

    Industry compliance standards

    • EU Fertilising Products Regulation (EU) 2019/1009
    • US FIFRA regulations for specialty fertilizer co-packaged pesticides
    • ISO 17323:2014 for controlled release fertilizer products
    • REACH Annex I registration for co-formulants

    Typical usage ratio

    • 0.2–1.2% w/w active ingredient relative to total granule mass, tailored based on application interval and irrigation regime

    Downstream process integration

    • Spray-applied to pre-formed fertilizer granules prior to packaging
    • Polymeric encapsulation ensures delayed active release
    • Release kinetics monitored via accelerated dissolution studies
    • QC sampling for both surface and embedded active content

    Final product types

    • Ornamental nursery slow-release granules
    • Landscape professional blends for turf and amenity greens

    4. Water-Dispersible Granule (WG/WDG) Formulation Manufacturing

    Formulation plants engineer Metalaxyl-m into water-dispersible granules (WG/WDG) suited for bulk commercial application in high-acreage field crops. Upstream, formulated blends contain wetting agents, clay carriers, and binders that undergo controlled extrusion and drying. Manufacturing controls granule hardness, dust generation, and dispersibility for operational safety and consistent tank-mixability in large-scale spraying equipment. Only certified WDG lines integrate full traceability, and trial data must demonstrate environmental safety and effective dispersion under field conditions.

    Industry compliance standards

    • WHO FAO specification for WDG formulation quality
    • ISO 9001:2015 certification of formulation facility
    • GHS labeling for hazardous mixtures
    • Regulatory registry in accordance with importing country’s pesticide law (e.g., India CIB&RC Guidelines)

    Typical usage ratio

    • 10–15% w/w active content in WDG, variance based on regional registration requirements and dosage tables for different crops

    Downstream process integration

    • Active blended with inert carriers, followed by controlled granulation
    • Final granules sized and screened before packaging
    • QC includes suspension stability, dispersibility in standard test media, and dust content
    • Each batch serialized for traceability to production records

    Final product types

    • Market-ready fungicidal WDG formulations for row crop growers
    • Custom-labeled granules for contract clients in regulated markets

    5. Export-Grade Wettable Powder Concentrate Production

    International agrochemical export operations require specialized wettable powder (WP) production lines, integrating Metalaxyl-m for distribution in jurisdictions favoring dry products for challenging logistics or climate. Critical attention centers on fine powder dispersion, shelf-stable blending with antifoam and anti-caking excipients, and dust reduction protocols to protect operator health. The WP process integrates in-line sieving, automated batching, and vacuum deaeration immediately prior to packing. Each lot’s performance undergoes validated suspension and dispersibility tests per local import standards.

    Industry compliance standards

    • FAO/WHO Codex standards for pesticide formulation
    • Good Manufacturing Practice (GMP) for agrochemical powders
    • Importing-country specific pest management programs (e.g., South Africa DAFF, Indonesia KPPI)
    • Controlled workplace dust exposure under local OHS regulations

    Typical usage ratio

    • 8–12% w/w active ingredient in WP bulk, varied by target market labelling and in-field dilution protocol

    Downstream process integration

    • Active pre-mixed with mineral carriers, followed by dry blending or pin-milling
    • Batch control based on gravimetric dosing and blend uniformity
    • Sieving step for powder flow and reduction of coarse particles
    • Finished goods packed in export-compliant, moisture-proof packaging

    Final product types

    • WP-concentrated fungicide for African and Asian field crops
    • Contracted bulk powder for localized re-packaging or direct farmer use
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    Certification & Compliance
    More Introduction

    Metalaxyl-m: A Closer Look from the Manufacturer’s Bench

    Introduction to Metalaxyl-m and Our Approach

    After decades of hands-on work in crop protection chemistry, we have learned what truly makes a fungicide stand out. Metalaxyl-m, sometimes referred to as Mefenoxam, stands out because it answers problems that every farmer and grower faces on the ground. Developed with an improved isomeric profile compared to standard metalaxyl, Metalaxyl-m delivers targeted disease control where it counts.

    Our manufacturing team controls every step, right from sourcing intermediates. We operate our production lines under tightly regulated conditions, so every batch meets stringent consistency standards. The purity matters not just to us, but to all the growers and formulators relying on this active ingredient.

    Understanding the Chemistry: What Sets Metalaxyl-m Apart

    From a chemist’s perspective, Metalaxyl-m is the enantiomerically enriched form of metalaxyl. This small shift in molecular structure impacts how plants metabolize the compound and how fungal cells are targeted. In practical fields—potatoes, grapes, tobacco, and vegetables—a farmer might only see healthier roots and stable foliage, but behind those results lies decades of process refinement that produces an active ingredient with higher bioactivity and lower use rates than earlier generations.

    Unlike racemic metalaxyl, Metalaxyl-m relies on the R-enantiomer, achieving the same or greater effect with nearly half the amount. Growers who have shifted to Metalaxyl-m formulations mention how they manage disease with lower environmental load. For a manufacturer, this change improves raw material usage, reduces manufacturing waste, and helps both ends of the supply chain meet stricter agrochemical regulations.

    Production Quality—A Closer Look at Specifications

    We know field performance begins at the synthesis reactor. Each lot is monitored for isomer ratio, active content, and byproducts. Metalaxyl-m comes off our lines as a white to off-white crystalline powder, typically packaged for bulk transport at purity levels above 97 %. Moisture, ash, and other technical parameters are continually tracked because even a small slip in consistency can lead to formulation headaches downstream.

    Growers and formulating partners often ask about visible differences: compared to generic metalaxyl, Metalaxyl-m flows more uniformly in powder mixes, and the dissolution rate in typical co-formulants speeds up tank prep in the field.

    Application and Use in Crop Protection

    Our customers operate in more than fifty countries, but the in-field stories follow a familiar thread. Growers struggle against seedling damping-off, downy mildew, late blight, and Pythium root rot, many of which cause losses before harvest even starts. Metalaxyl-m integrates into preventative and curative spray programs across dozens of crops—from soybeans to ornamentals—forming the backbone of best-practice Integrated Pest Management.

    Users report that Metalaxyl-m—unlike older chemistries—moves more efficiently through the plant’s xylem, protecting both treated parts and new shoots. In our own greenhouse trials, we see reduced lesion counts on treated tomatoes compared to untreated controls. Farmers tell us that treated seed lots show stronger emergence and better stress resistance, especially in wetter seasons.

    Many growers employ Metalaxyl-m as a wettable powder, suspension concentrate, or granule, selecting a formulation that fits their equipment and water conditions. Our team consults directly with formulation scientists, making adjustments based on field input. Sometimes this means tweaking surfactant blends or particle sizing for uniform dispersion, so that in the field, spray rigs finish clean and well-mixed, whether handling a thousand hectares or a garden plot.

    Field Impact and Resistance Management

    Over years of experience, we have seen how repeated use of any single active ingredient can lead to diminishing returns. Some fungi, especially Phytophthora and Pythium species, adapt quickly. For this reason, Metalaxyl-m only reaches maximum lifetime potential when integrated into a rotation plan. We always recommend alternation or co-application with other modes of action—ideally as part of a well-designed resistance management strategy.

    We work alongside agricultural extensionists and participate in field demos. Many times, growers bring us samples from their own operations, showing both successes and emerging challenges. Whether in potato blight belts or vineyard mildew hotspots, the message is the same: stewardship is key.

    Comparing Metalaxyl-m to Other Active Ingredients

    On the manufacturing floor, differences between actives go far beyond the chemical warehouse. For instance, compared to other systemic fungicides like azoxystrobin or fosetyl-Al, Metalaxyl-m targets a different biochemical pathway inside the fungus. This difference allows formulators to design combination products that tackle resistance head-on.

    Growers have often asked us about the practical impact of these differences. With Metalaxyl-m, rain fastness and soil mobility both matter. In direct comparison trials, Metalaxyl-m maintains its protective effect even after irrigation or heavy dew, thanks to its high uptake and movement inside the crop. Other fungicides may remain more surface-bound, limiting their reach to the treated spray zone. Our feedback loop with users has led us to continually improve on microencapsulation and slow-release technologies, aimed at extending intervals and reducing the number of applications needed through a season.

    Some might notice that generic metalaxyl still floats in global markets, often as a cost-saving option for low-spec applications. Our view, based on years in production, is that the improved performance profile per gram of Metalaxyl-m far outweighs short-term savings from using older molecules. In disease-prone environments or under regulatory scrutiny, re-treatment costs and crop loss carry far more weight than the small cost difference at purchase.

    Manufacturing Realities and Regulatory Drivers

    Producing Metalaxyl-m is not just a matter of running a batch reaction and filling drums. Audit trails, process validation, and batch traceability are woven into our daily routine. Every process must withstand scrutiny from both domestic and international regulators. In recent years, we have faced tighter limits on impurities, stricter worker exposure standards, and frequent residue monitoring programs in export markets. Our team works closely with compliance experts to adjust and refine processes long before regulations change. This forward planning controls recall risks for our customers—an essential part of earning trust.

    For us, product stewardship means more than supplying an ingredient. We maintain regular training programs for dealer staff and agronomists, and issue field bulletins on responsible use. If an application error or out-of-spec batch ever shows up downstream, we treat the incident as a process improvement opportunity, not a public relations exercise.

    Environmental and Worker Safety Initiatives

    The conversation about crop protection has shifted over the past decade. Farmers and consumers expect not only strong yields, but proof that safeguards are in place for water, pollinators, and farm workers. To address these needs, we have reengineered our Metalaxyl-m line with multiple containment steps, in line with ISO and GACP standards. We designed our drum-filling lines for dust minimization and automate our packaging area to keep operators safely distant from active material.

    In formulation, we routinely test for leachable fractions and carry out simulated rainfall experiments to model runoff risks. This data helps growers develop their own management plans, keeps field exposure in check, and reduces environmental footprint on sensitive watersheds.

    User Experience and Crop Value Arguments

    One reason users keep coming back to Metalaxyl-m lies in the outcome they see. Higher marketable yields in vegetables, more uniform emergence in corn, reduced risk of seedling stand loss—these are results that matter directly to the grower’s bottom line. Our staff regularly visit commercial farms and trial plots. We walk the rows, collect field data, and look at results alongside our partners. Direct feedback from users influences adjustments to both granule and liquid products.

    These discussions often uncover new questions or emerging issues. In regions where soil pH or mineral content differ, tweaks to application timing and mixture partners sometimes improve results. Our technical teams keep in touch with university extension researchers, sharing data and helping to validate application intervals or tank-mix partners in real-world conditions.

    In vegetable transplants, where root rot causes sudden and severe loss, Metalaxyl-m’s fast uptake minimizes the time plant roots spend unprotected. In grape vineyards, trials have shown that a properly timed application keeps downy mildew incidence low throughout the critical bloom and fruit set periods. These aren’t marketing claims—they’re repeated observations. We include site-specific recommendations in our guidance to reduce both overuse and under-dosing, reinforcing the principle that well-timed, target-focused application delivers the greatest return on investment.

    Supporting Ongoing Research and Adaptation

    Our manufacturing plant isn’t just a chemical factory. It doubles as a research site, where we investigate new formulation carriers, test compatibility with biological actives, and stress-test the product under simulated storage and transport conditions. Recent projects explore ways to embed Metalaxyl-m within granular fertilizer matrices, potentially offering even greater planting efficiency or root-zone targeting.

    Continuous feedback from agronomists and crop consultants influences how we refine the product for different regional needs. For example, in tropical growing zones, high rainfall presents run-off risks and necessitates faster soil absorption. In arid environments, compatibility with drip irrigation, seed treatment slurries, or minimal-tillage methods matters more. Several growers have reported less leaching and better rot suppression with our latest granular offerings compared to liquid tank mixes on sandy soils.

    Future-Proofing Crop Protection

    Pressure from both regulators and global food buyers makes today’s manufacturing environment more demanding than ever. We monitor global MRL (Maximum Residue Limit) requirements for vegetables and fruit crops, updating our processes as new standards take hold in import markets. Recent expansions in field residue testing have led us to review every step—from solvent selection to final packaging—to avoid carryover or cross-contamination.

    Reducing off-target exposure stands as a long-term priority. While Metalaxyl-m’s systemic movement inside crops improves its targeting, we continue to research encapsulation and co-formulant technologies that keep spray drift and user exposure down to the lowest possible levels. Collaboration with spray equipment suppliers ensures that our technical team understands the realities of nozzle choices and pressure variations, so growers can rely on consistent field results regardless of sprayer type.

    This attention to process and environmental compatibility delivers benefits beyond compliance. Buyers in retail and export channels increasingly seek proof of traceability, environmentally conscious production, and product stewardship. Documenting each batch and responding rapidly to trace-back requests reassures our customers and opens doors to added-value, certified crop programs.

    Final Thoughts from the Manufacturer’s Perspective

    Manufacturing crop protection products like Metalaxyl-m brings a unique vantage point: we witness both ends of the supply chain, from chemical synthesis through to the sprayer nozzle and harvest yield. Our years of experience have convinced us that stewardship, adaptability, and shared insight form the backbone of crop protection’s future.

    We meet challenges by keeping our process transparent, our support responsive, and our products consistent. We keep listening to users, testing in real fields, and investing in cleaner, safer manufacturing. With every lot of Metalaxyl-m we produce, we aim not just for regulatory compliance but for real value that meets growers’ changing needs.

    Colleagues in the field, thank you for the trust and candor you bring to each growing season. Every new question and unexpected field result pushes us to refine, adapt, and improve. In return, we commit to clear communication, continuous improvement, and shared progress.