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Erythrulose

    • Product Name Erythrulose
    • Alias D-Erythrulose
    • Einecs 253-048-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    778262

    CAS Number 533-50-6
    Molecular Formula C4H8O4
    Molecular Weight 120.10 g/mol
    Appearance Colorless to pale yellow liquid or solid
    Solubility Soluble in water
    Melting Point 121-123 °C
    Boiling Point Decomposes
    pH Approximately 7 (in 1% solution)
    Chemical Name 1,3,4-Trihydroxy-2-butanone
    Usage Commonly used in self-tanning cosmetic products
    Odor Odorless
    Synonyms D-Erythrulose; D-threosulose
    Density 1.24 g/cm³

    As an accredited Erythrulose factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Erythrulose is packaged in a 100g amber glass bottle with a screw cap, featuring clear labeling and safety instructions.
    Shipping Erythrulose is typically shipped in tightly sealed containers, protected from light, moisture, and extreme temperatures. It should be handled with care, following standard chemical transport regulations. The packaging must be clearly labeled, and shipping documentation should comply with local and international safety guidelines to ensure safe and efficient delivery.
    Storage Erythrulose should be stored in a tightly closed container, protected from light and moisture, in a cool, dry, and well-ventilated area. Ideally, storage temperatures should be below 25°C (77°F). Avoid exposure to heat and strong oxidizing agents to prevent degradation. Proper labeling and adherence to safety regulations are essential for safe handling and storage of erythrulose.
    Application of Erythrulose

    Applications of Erythrulose in Industrial Manufacturing

    Erythrulose finds specialized use in a range of regulated manufacturing sectors, particularly in formulations requiring mild, controlled reactions with biomolecules. Our plant-grade Erythrulose supports precise process integration across pigment chemistry, custom dermal product bases, and advanced skin-contact materials. Below we detail several industrial application routes validated in established chemical and personal care industries globally.

    1. Self-Tanning Ingredient for Cosmetic Formulations

    Cosmetic manufacturers incorporate Erythrulose into self-tanning emulsions, serums, and lotions due to its ability to produce a gradual, natural-looking skin tone through a Maillard-type reaction with keratin proteins. In these systems, suppliers distribute active ingredient blends directly to dermal product lines, where they combine Erythrulose with dihydroxyacetone (DHA) for a balanced color effect and improved skin compatibility. Manufacturers conduct rigorous microbial and purity controls, ensuring compliance and batch stability throughout the production cycle to support both European and North American regulations.

    Industry compliance standards

    • EU Cosmetic Regulation (EC) No 1223/2009
    • Cosmetic Ingredient Review (CIR) Panel Monographs
    • US FDA 21 CFR 700 Subpart B Cosmetic Product Regulations
    • ISO 22716 GMP for Cosmetics

    Typical usage ratio

    • 0.5% – 3% by weight in the aqueous phase of final emulsion
    • Ratio typically adjusted based on application area and combined DHA content

    Downstream process integration

    • Added during cold-phase or cool-down stage after emulsification
    • Requires pH adjustment (range 4.5–5.5) to maintain solution stability
    • Protected from direct light and excess temperature throughout blending
    • Integrated QC includes color index and microbial load testing

    Final product types

    • Self-tanning lotions and creams
    • Sunless bronzing sprays
    • Professional skin-tinting drops
    • Gradual tan moisturizers

    2. Colorant Precursor for Personal Care Biopigments

    Leading pigment technology companies use Erythrulose as a selective precursor for custom biopigments in leave-on skin products and certain medical skin devices. When reacted under controlled conditions, it generates stable, semi-permanent chromophores which provide consistent coloration. Formulators choose precise ratios and initiate reactions post-emulsification to enable uniform dye development. The mechanism avoids heavy metal salts, meeting stringent safety and heavy metal release requirements for skin-contact ingredients.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006—Annex XV for pigment precursors
    • ISO 16128 Natural Ingredients Standard (where applicable)
    • Japanese Ministry of Health, Labour & Welfare (J-MHLW) for quasi-drugs
    • US FDA 21 CFR Parts 73 & 74 on color additives for external use

    Typical usage ratio

    • 1% – 2.5% in pigment generation systems
    • Lower or split-dosing protocols applied for device-coated or patch products

    Downstream process integration

    • Added to pre-mixed water phase with strict temperature/time controls
    • Staged oxidation process post blending to fix color precursor
    • Requires nitrogen blanketing for bulk synthesis
    • QC includes spectrophotometry for color saturation and unreacted residue analysis

    Final product types

    • Biobased color additives for skin-contact medical devices
    • Pigmented creams and gels
    • Specialty pigment serum concentrates
    • Temporary tattoo transfer films

    3. Intermediate in Advanced Biochemical Research Reagents

    Biotechnology and life sciences manufacturers apply Erythrulose as a tracer carbohydrate and mild reducing agent in non-clinical diagnostic kit developments. Here, it serves as a control molecule for validating Maillard reaction kinetics, enabling developers to benchmark enzymatic browning or glycation in synthetic test matrices. Material specification and handling strictly follow Good Laboratory Practice (GLP) and chemical purity requirements, with traceability at every blend and dispense stage.

    Industry compliance standards

    • OECD GLP Principles
    • ISO 13485 for medical device laboratories (where applicable)
    • US FDA QSR for Lab Developed Tests (LDTs)
    • Analytical reagent grade specifications (ACS, Ph. Eur., JP)

    Typical usage ratio

    • 0.1% – 1% in research buffer or model system
    • Adjusted based on experimental design and analytical detection limits

    Downstream process integration

    • Measured addition to assay buffer or reconstitution solution
    • Final dilution specified before colorimetric or analytical test application
    • QC based on batch HPLC and certificate of analysis per lot
    • Packaging with desiccant under low moisture conditions

    Final product types

    • Research-only biochemical kits
    • In vitro skin glycation testing solutions
    • Bioanalytical Maillard reaction controls
    • Diagnostic reagent set components

    4. Reactant for Functional Sugar Polyol Synthesis

    Specialty chemical plants utilize Erythrulose as a feedstock in the synthesis of customized polyols and sugar-derived monomers. Manufacturing processes convert it through catalytic hydrogenation to erythritol or subsequent chemical reduction steps for high-purity intermediates. Process parameters undergo regular monitoring to prevent byproduct formation and ensure consistent physical properties in downstream polymers and plasticizers. Manufacturers ensure compliance with quality and food contact directives for materials entering indirect contact supply chains.

    Industry compliance standards

    • European Commission Plastics Regulation (EU) No 10/2011 (where monomers used in food contact)
    • US FDA 21 CFR 177 indirect food additive regulations
    • ISO 9001 certified process quality systems
    • Japanese Positive List for Food Contact Materials

    Typical usage ratio

    • Feed rate based on catalytic reactor load, typically 100 g/L–300 g/L for hydrogenation batches
    • Process engineers adjust input based on conversion yield and final purity specifications

    Downstream process integration

    • Pumped in as aqueous or concentrate solution to hydrogenation reactors
    • Reaction conditions strictly regulated (temperature, catalyst type, pH)
    • Post-reaction purification by crystallization or ion-exchange chromatography
    • Quality tests for residuals and byproduct sugar alcohols at discharge

    Final product types

    • Food-grade polyols (e.g. erythritol)
    • Eco-friendly co-monomers for bioplastics
    • Low-calorie sugar substitutes (as intermediates)
    • Technical-grade sweetener blends
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    Certification & Compliance
    More Introduction

    Erythrulose: Experience, Quality, and Performance You Can Measure

    Our Long Road with Erythrulose

    Our team has been making erythrulose for more than a decade. Over those years, we’ve seen sunless tanning shift from a niche market to a mainstay of skincare. Early on, options for high purity erythrulose remained limited, and real consistency was hard to come by. We set out to do better using steady hands, simple equipment, and careful planning. This isn’t a distributor’s opinion—it’s daily work, from packing to quality testing. We have shaped every step ourselves, keeping standards high and listening to feedback from labs and formulators who care about the end user.

    Our erythrulose model is manufactured using a microbial fermentation process, followed by a series of filtrations and crystallizations. We’ve chosen not to use plant extracts or fruit waste in our workflow, as they often bring unpredictable by-products that interfere with clean results. This choice delivers erythrulose as a fine, free-flowing powder that measures above 99% purity in our post-production analysis, supported by robust HPLC testing. Some others in the industry settle for 95–98% with a more visible pink or brown hue. Ours instead comes out as a colorless to faintly off-white powder, proving itself both in the chemistry and in daily use.

    Why Our Approach Matters to Your Application

    Erythrulose draws a line in the sunless tanning market. Most formulas pair it with DHA to create a deeper, more lasting skin tone. On its own, erythrulose produces a gradual, coppery glow that doesn’t streak quite as easily as pure DHA-based options. Skin irritation stays low, and the aroma after application is muted compared to single-DHA blends. Our own samples wind up in leading lotions and sprays specifically because our process keeps heavy metals, residual solvents, and proteins out of the final product. The reality in this industry remains simple: even a few percent difference in impurity profile shows up instantly on pale skin, with spotty results or uneven fades. Years of feedback and batch improvements drive our process today. We prioritize eliminating these headaches before the ingredient ever leaves our floor.

    We produce erythrulose in batches measuring from 5 kg pilot runs to commercial 200 kg productions, storing it at controlled temperature and humidity. Some have tried to cut corners by mixing in more maltodextrin or bulking agents, hoping to smooth out cost swings or make handling easier. Instead, we focus on full recovery of erythrulose with minimal binders, guiding customers who want to blend their own carrier systems instead of working around someone else’s shortcut.

    Model and Specifications: Built for Modern Formulations

    In the early years, most erythrulose batches on the market carried an average moisture content of 2–3%. We have invested in rotary vacuum dryers and custom crystalline sieves, dialing our finished product to under 1% moisture on average. Lower moisture not only keeps the material free-flowing and easy to dissolve, but also protects against clumping in storage. Color, odor, and flowability matter during bulk handling, not just in the lab. As for solubility, our product dissolves in cold or warm water. Some partners in climate-controlled filling rooms have run tens of thousands of units without encountering caked residues in their mixing tanks.

    Our model supports pH ranges from 4 to 8—not just the textbook 5 to 7 window—making it friendly for formulators chasing new product textures or milder pH profiles. Stability testing stretches past six months under accelerated conditions, with little loss of color or tanning activity even in polyethylene packaging. We document every batch and archive golden standards so that every box heading out the door matches, whether it’s for spray tan booths in a chain of salons or high-speed bottling in a contract manufacturer.

    Quality Assurance Without Excuses

    Few things cause more headaches than inconsistency in high-value cosmetic ingredients. We’ve learned that lessons don’t always show up in the certificate of analysis. Our in-house lab checks not only assay and moisture but also looks for subtle contaminants—such as low-level aldehydes or sugars that sneak in during fermentation gone wrong. Supply chain partners have sent us samples with as much as 4% mixed saccharides or over 30 ppm lead content, assuming it wouldn’t be picked up during normal skin testing or cosmetic batch analysis. Those surprises risk more than profits. They threaten brands’ reputations and customer safety. That’s not a risk we entertain.

    With us, batches aren’t released without careful LC-MS scans for trace contaminants and a cross-check against both EU and US cosmetic ingredient rules. We hammer away at the uncomfortable details of trace analysis, and we’re always ready to jump on the call with a customer’s lab team to troubleshoot odd results or run custom validation. We also handle batch recall communication directly if anything ever arises—a process we’ve rehearsed but, thanks to proper diligence, never had to carry out in over 60 combined years of production experience across our facility leads.

    Differences That Add Up

    We don’t treat erythrulose as a commodity. The differences extend far beyond just the assay number on the COA. Microfine sizing reduces dusting and improves dispersibility in powder pre-mixes for skincare products. We avoid the musty, off-sweet aroma sometimes left by incomplete fermentation steps from other makers, which our in-house trained panel picks up in blind pairwise testing. Rapid-turn logistics help us ship fresh lots instead of aged stock that’s passed through three warehouses and months of uncontrolled storage, facing air, humidity, and temperature swings that slowly reduce shelf life and increase polymerization risks.

    Some blends in the market tout “stabilized” versions, including extra antioxidants or surfactant residues, but those additions often create more compatibility challenges in finished skin products. We stick to the basics, shipping erythrulose with no added preservatives or carriers unless specifically requested. For brands who understand what real purity means, that difference rises to the surface in test batch after test batch. Even after years in the field, we’re available to audit or consult with formulation improvements, often working with our partners’ R&D managers side-by-side to squeeze out the last wrinkle or spotty finish that could cost them reputation and revenue.

    Meeting Modern Safety and Regulatory Demands

    Cosmetic ingredient scrutiny continues to tighten. New EU restrictions on glyoxal content in suntan solutions have forced some suppliers to rework formulations or bounce batches back to their fermentation partners. We meet these detailed requirements by constant review of both our process and external guidelines. Certificates of analysis detail glyoxal, heavy metals, and bioburden for every lot shipped. For clients in North America, our documentation lines up with FDA monographs and INCI requirements, setting aside tempting shortcuts that could lead to hold-ups or red tape downstream. We stay ahead of the changes not just for compliance, but with a clear goal: to protect the hard-earned trust built from years of reliable supply and open communication with our customers.

    In addition, many large brands want allergen-free, vegan, and GMO-free solutions. Our erythrulose ticks those boxes by virtue of our controlled fermentation and exclusion of animal-derived enzymes or feedstocks. That commitment grew out of serious conversations in our own operations meetings after seeing label risk stories in the news. Nobody here wants to read a headline about product recalls traced back to their batch of raw material, and we work to make sure our partners never have to have those conversations, either.

    Real-World Applications and Feedback

    The list of applications using our erythrulose grows every year. Our regulars run classic sunless tan mousses and gels, but the ingredient also turns up in wash-off bronzers, pre-tan prep serums, and even a few color-correcting skincare creams. After talking with several smaller artisanal makers who had struggled for years to get even results at home, we reconfigured our pack sizes. Now, both contract manufacturers and indie boutique brands work from the same bulk barrels and smaller pails, because we’ve learned that great products shouldn’t just be for those ordering metric tons at a time.

    Direct feedback from users tells us where batch improvements matter. Faces or legs aren’t the only palettes. We get return data about ease of dissolution, shelf life in complex emulsions, and user outcomes. One clean batch can mean a new product launch for a startup, while a single failed supply can shut down a whole season’s lineup for even the biggest retail brands. Every real fix—such as tightening our humidity at packaging or introducing triple-sealed liner bags—has grown from these open conversations with R&D teams and production managers prioritizing what works over marketing flash.

    Ongoing Challenges and Our Solutions

    Producing erythrulose isn’t simple, and no one should claim it is. It’s a living process at every step—microbial strains throw curveballs, changes in water quality change the whole run, and unexpected logistics delays try to unravel careful planning. Scaling up to larger batches throws up new roadblocks, from managing heat distribution in crystallization tanks to ensuring no cross-contamination from other actives we might be producing in-house. We’ve met each problem with a blend of experience and willingness to reinvest. Our teams run test fermentations on new strains as backup, holding their performance up to years of archived samples and keeping honest records. We throw out a lot of substandard product because chasing every last kilogram rarely pays off for anyone in the long run—least of all the end user.

    Every now and then, a new ingredient trend shakes up the market, like blending erythrulose with sugar beet-derived actives or using it as a backbone for enzyme-tanning systems. We stay connected to formulation scientists around the world, sitting on advisory calls and trade association sessions, digging into what actually solves customers’ headaches and what’s just trend-chasing. We believe in the foundation first: do one thing right, then look for smart ways to move forward rather than chasing the latest craze.

    Supporting Sustainable Practices

    The green chemistry movement continues to grow in cosmetics and personal care. Our own supply chain reflects those values: water treatment onsite, careful tracking of fermentation inputs, and full traceability for every raw material. By mapping out waste streams and recycling as much as possible, we cut down environmental impact without sacrificing performance. Too many shortcuts in the name of cost savings backfire, harming both reputation and long-term business models. We’ve chosen to set up local partnerships with logistics providers, shrinking transit routes and working with regional recyclers. Our customers notice the difference, not just in a sustainability box on a website but in the reliability and accountability baked into every delivery.

    We approach sustainability as an evolving process. By staying honest about where gaps remain and sharing our own data on energy use or waste output, we invite scrutiny and new ideas. No one learns anything by hiding behind buzzwords. That means opening doors to customer site visits, third-party audits, and real conversations about carbon footprint for those who care about end-to-end responsibility. Transparency and hard data—rather than slogans—have helped us stay in business for years while others have come and gone.

    Why Erythrulose Remains Essential

    The skin care world doesn’t stand still. Market pressures, changing tastes, regulatory hurdles, and shifting supply lines all shape how sunless tanning and color cosmetic products evolve. Through it all, erythrulose offers a combination of stability, mildness, and predictability that no new entrant has managed to push aside. We’ve helped small brands launch with confidence and equipped multinational research teams as they adapt to consumer requests for subtler color, longer-lasting results, and lower risk. We can’t claim erythrulose as a silver bullet, but our long track record says plenty: handled right, it makes great products far more attainable.

    Today, erythrulose may not hold the market share of long-standing actives like DHA, but its presence in high-end self-tanners, salon solutions, and global skincare lines confirms its value. Our batches contribute to products praised for natural results, smoother fades, and better compatibility with sensitive skin. The difference isn’t accidental. We believe manufacturing should be personal, meticulous, and open to scrutiny. Trust comes from repetition, from owning mistakes, and from a commitment to doing things well—again and again.

    A Simple Promise

    Those of us in chemical manufacturing know small changes matter as much as big transformations. Our erythrulose is the result of ongoing conversations with brands, consumers, and regulatory partners. We listen, we adjust, and we keep quality as the main principle. Every time we inspect an outgoing shipment, check a raw material certificate, or walk through a batch test with someone’s R&D team, we’re reminded why this work matters. Years of problem solving and a refusal to cut corners form the backbone of what we send out the door every day. That’s our perspective, and it shapes every gram of erythrulose that leaves our site.