Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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DL-Ornithine

    • Product Name DL-Ornithine
    • Alias Ornithine
    • Einecs 210-510-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    912685

    name DL-Ornithine
    chemical_formula C5H12N2O2
    appearance White crystalline powder
    CAS_number 3184-13-2
    solubility_in_water Freely soluble
    melting_point Approximately 223°C (decomposes)
    pH_value 5.0–7.0 (1% solution)
    odour Odourless
    storage_temperature Room temperature
    stability Stable under recommended storage conditions
    purity Typically ≥98.0%

    As an accredited DL-Ornithine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White plastic bottle labeled "DL-Ornithine, 100g." Features tamper-evident seal, batch number, storage instructions, and supplier information.
    Shipping DL-Ornithine is shipped in tightly sealed, clearly labeled containers to prevent moisture and contamination. Packaging complies with relevant safety regulations, and the chemical is typically transported at ambient temperature. It is classified as non-hazardous, but care is taken to avoid exposure or inhalation during handling and delivery to ensure safe transit.
    Storage DL-Ornithine should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area. Protect it from moisture, heat, and direct sunlight. Avoid exposure to strong acids, bases, and oxidizing agents. Store at room temperature unless otherwise specified by the manufacturer. Always follow local regulations and safety guidelines for chemical storage.
    Application of DL-Ornithine

    Applications of DL-Ornithine in Industrial Manufacturing

    DL-Ornithine serves as a specialty intermediate in several targeted industrial sectors, supporting biochemical synthesis, animal nutrition, medical product preparation, and lab-scale research. Here we detail verified downstream usage from the perspective of a primary manufacturer, covering strict industry standards, process workflows, and practical end-product types.

    1. Amino Acid-Based Pharmaceutical Synthesis

    DL-Ornithine functions as a protected building block and precursor in the multi-step chemical synthesis of complex amino acid derivatives for pharmaceutical ingredients. Companies use it for peptidomimetic design, specialty APIs, and as a starting unit in prodrug manufacturing. Compliance with pharmacopeial purity and traceability is required during integration into GMP batch records and process validation for pharmaceutical supply chains. DL-Ornithine typically enters at the intermediate or protected-amino stage, following precise weighing and dissolution protocols ahead of coupling or elongation reactions in peptide synthesis suites. Downstream end products include ornithine-based APIs, semi-synthetic enzyme substrates, and injectable formulation components.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • USP/NF monograph specifications (if applicable for intermediate)
    • EDQM CEP submission requirements
    • 21 CFR Part 211 for finished dosage compliance

    Typical usage ratio

    • 0.5–5% w/w in the total synthetic mixture depending on molecular weight of target product and reaction stoichiometry
    • Adjustment based on peptide chain length and coupling efficiency

    Downstream process integration

    • Charged as an intermediate in automated or manual peptide synthesizers
    • Pre-conditioned through pH adjustment and filtration before acylation or condensation steps
    • Batch records record material identity and lot traceability per API requirements

    Final product types

    • Peptide and polypeptide APIs (Active Pharmaceutical Ingredients)
    • Ornithine-based drug intermediates
    • Prodrug compounds using ornithine linkers
    • Diagnostics reagents containing labelled ornithine residues

    2. Animal Feed Additive Formulation

    DL-Ornithine is employed in nutritional supplements and premixes for livestock and aquaculture feed, particularly where L-ornithine monohydrochloride is not specified or when cost drives use of the racemic form. Its role includes ammonia detoxification in non-ruminant diets and as a growth performance modulator in specialized feed formulations. Compliance is critical with national and global feed additive directives. Actual inclusion occurs as a microingredient in premix blending facilities following precise metering, sometimes paired with other amino acid supplements in total mixed ration (TMR) integration. Animal feed products use DL-Ornithine heterogeneously, with intake ratio set by nutritional guidelines and species-specific performance trials.

    Industry compliance standards

    • EU Feed Additive Regulation (EC) No 1831/2003
    • AAFCO (Association of American Feed Control Officials) listings
    • FSMA Animal Food standards for traceability and safety
    • ISO 22000 Food Safety Management Systems (premix plants)

    Typical usage ratio

    • 10–500 mg/kg of total feed, adjusted by animal species and performance outcome
    • Dosage set via veterinarian recommendation or nutritionist optimization, often lower for initial supplementation formulations

    Downstream process integration

    • Dosed directly into vitamin-amino acid premix tanks as a free-flowing powder
    • Homogenized with base meal and pelletized using low-heat extrusion to maintain functional integrity
    • Final QC for blend uniformity and batch retention samples for regulatory audit

    Final product types

    • Poultry and swine amino acid premixes
    • Aquaculture pellet feeds (e.g., for shrimp and marine finfish)
    • Specialized amino acid boluses for calves or pets
    • Livestock growth-promoting feed concentrates

    3. Cell Culture Media and Bioprocessing Reagents

    DL-Ornithine is widely included as a component of basal or custom cell culture media in research and commercial bioprocessing. It supports cell growth, differentiation, and metabolic pathway studies, especially in the production of recombinant proteins and monoclonal antibodies. Regulatory compliance with laboratory reagent purity (often ≥99%) is essential, with some applications requiring cell-culture tested certification. DL-Ornithine is solubilized and sterile-filtered into media concentrates prior to large-scale or small-scale inoculation. Media manufacturers carefully adjust dose based on published cell line requirements and experimental protocols. Finished goods are distributed to research, diagnostics, and biomanufacturing organizations.

    Industry compliance standards

    • ISO 13485 for medical device and reagent manufacturers
    • USP <1043> Ancillary Materials for Cell, Gene, and Tissue-Engineered Products
    • EMEA Guidelines on raw material traceability for biological therapeutics (EMA/CHMP/BWP/429241/2013)
    • Certificate of Analysis and Endotoxin Control (per LAL test)

    Typical usage ratio

    • 5–40 mg/L in complete cell culture media, with adjustment for suspension versus adherent cell types
    • Optimization required for specific cell strains or bioprocess parameters

    Downstream process integration

    • Added to powdered or liquid base media during batch mixing
    • Introduced prior to sterile filtration and aseptic filling
    • Subject to quality control for solubility, pH, and endotoxin prior to shipment

    Final product types

    • Complete DMEM or RPMI media variants for mammalian cell culture
    • Recombinant protein manufacturing media supplements
    • Tissue culture reagent kits for research labs
    • Cell therapy and vaccine production media

    4. Diagnostic Reagent and Enzyme Substrate Manufacturing

    Industrial manufacturers utilize DL-Ornithine as a standard substrate for calibration, assay development, and reagent production in clinical chemistry and in vitro diagnostics (IVD). The compound acts as a measurable reactant in ornithine assay kits and is included in enzyme activity measurement protocols, particularly for ornithine transcarbamylase and related diagnostic tests. Regulatory compliance focuses on IVD-specific quality benchmarks and batch-to-batch reproducibility. Users introduce DL-Ornithine at the buffer or lyophilization stage during bulk reagent preparation and perform thorough QC on analytical purity and stability for kit assembly. Resulting products enter the medical diagnostics marketplace as complete kits or intermediate reagents.

    Industry compliance standards

    • IVDR (In Vitro Diagnostic Regulation (EU) 2017/746)
    • FDA 21 CFR Part 820 (Quality System Regulation for medical devices and diagnostics)
    • ISO 13485:2016 for design and manufacture of medical devices
    • Certificate of Analysis with HPLC and enzymatic activity validation

    Typical usage ratio

    • 0.01–1.5 mmol/L in aqueous buffers or lyophilized substrate preparations, customized by assay sensitivity
    • Concentration set by enzyme kinetics and manufacturer kit instructions

    Downstream process integration

    • Weighed and dissolved into diagnostic buffer matrices
    • Aliquoted with automated filling, followed by freeze-drying for stable kit assembly
    • Batch QC with reference enzyme to confirm substrate functionality

    Final product types

    • Clinical ornithine quantification kits for serum or plasma
    • Enzyme-based ammonia determination assays
    • Colorimetric substrate standards for laboratory analyzers
    • Automated biochemistry analyzer reagents
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    Certification & Compliance
    More Introduction

    DL-Ornithine: Experience from the Factory Floor

    At our site, DL-Ornithine is more than just a name scribbled on a barrel. It comes straight off our reactors, every batch built from decades of chemical experience and strict hands-on control. This alpha-amino acid, with the CAS number 3184-13-2, stands out in both research and industrial use for its unique structure, easy handling, and transparent quality. We see researchers and manufacturers come through for it, drawn by the consistent purity and straightforward, reliable performance. Our process follows up-to-date standards, carefully watched at every stage, from raw feedstock verification to drying and packing—all under the same roof, carried out under the same eyes every step of the journey.

    What Makes DL-Ornithine Special?

    DL-Ornithine wears its special touch in its versatility. Unlike L-ornithine or D-ornithine, which single out only one chiral form, DL-Ornithine brings both mirror-image forms together. This racemic mixture finds a home in synthetic chemistry, fermentation processes, and nutritional research. Both enantiomers show different biological responses, so using the pair allows wider screening in experimental setups. In microbial fermentation, the balance plays nicely with custom applications, where tweaking the amino acid source can make all the difference to yield.

    Our facility never takes shortcuts—every shipment of DL-Ornithine comes with batch data to track not just purity, but also physical characteristics: appearance, particle size, and solubility. The powder is off-white, easy to process, and handled in high-precision batches. Consistency truly matters. Clients rely on a product they can weigh, dissolve, and blend into new media without drama.

    Our DL-Ornithine: Specifications Learned by Hard Experience

    Through in-house testing, we've zeroed in on the spec that matters: a purity greater than 98%, with moisture content below 1%. Density, particle flow, and absence of heavy metals come tested each batch on our own lines. Every new lot carries these signatures, stamped by our engineers in the lab right next to production. The feedback we get—good and bad—drives each tweak. Early on, “caking” became a frustration for some customers. Instead of applying a generic solution, we traced the issue to trace water in local air, then sealed our packaging more tightly and dehumidified our packaging rooms. That’s made an immediate improvement for everyone downstream.

    We pay attention to solubility and residue. In biochemical work—enzymatic assays, microbial broth enrichment, diagnostic kits—our clients tell us that residue left behind in solution creates noise and failed controls. So, we filter relentlessly, double-test at dissolving, and run baseline analytical checks again before shipping.

    DL-Ornithine Uses Our Researchers Track

    Scientists studying the urea cycle or nitrogen metabolism seek DL-Ornithine to run reaction comparisons, benchmark enzyme profiles, and compare uptake. The pure racemate offers researchers the broadest look at enzyme systems, since both L- and D-forms pass through as substrates, inhibitors, or controls. That opens new possibilities when running kinetic experiments or screening microbe cultures.

    Nutritional supplement makers have used our DL-Ornithine in formula testing. We always clarify: synthetic DL-form is not identical in metabolism to L-ornithine alone, and we recommend customers engineer their blending in line with local regulation and intended use. In feed applications, both animal researchers and feed millers come to us looking for that fine balance between bioavailability and cost. The DL-form flows clean into granules, fits right into feed premixes for aquaculture or poultry, and gives reliable nitrogen supply.

    In chemical synthesis labs, DL-Ornithine steps in as a starting block. The twin enantiomers offer unique branching points for building new molecules. In peptide synthesis, our material serves as a protected starting amino acid or as a backbone for active analogs. This mirrors our own roots—years ago our first application came from a pharmaceutical intermediate order, and every run since has deepened our mastery of reproducibility and purity.

    Comparison with L-Ornithine and D-Ornithine

    Some buyers ask why not just use the pure L-form? There’s a place for that, especially where biological activity hinges on a single chiral molecule. But the racemate offers a technical simplicity and a lower cost. Our process creates both enantiomers in one run, which skips expensive separation steps and minimizes waste. DL-Ornithine stays more affordable for applications where selective chiral interactions are not the target. For those who need exclusively L- or D-ornithine for chiral selectivity, we recommend parallel sourcing or custom synthesis routes—something we advise on, but keep DL-form as a tougher, more flexible workhorse for more general use.

    Our Staff’s Look at Purity and Quality Control

    Every operator in our plant learns why batch purity matters. We repeat purity checks at every logical stage. Testing happens on equipment we've fine-tuned for this molecule: HPLC, FTIR, and trace metal analysis run in sync with visual inspections. Even a tiny deviation on purity charts brings a visit to the reactor or dryer. In the past, a single off-color batch led to switching suppliers for our catalyst—no exceptions. We’re always hands-on, never farming out job steps to cut costs.

    Our team ran into foreign particle contamination eight years ago—fibers from an upstream solvent drum. Since then, staff training covers not just production, but also handling of every consumable that touches the product. We keep logs of every shift; traceability links back to the original lot of every additive and solvent. This nuts-and-bolts approach lets us stand by every ton that leaves the dock.

    We build for tight moisture control. High humidity spells trouble for shelf life in amino acids. Our process rooms use monitored dehumidifiers, with daily logs pinned to the entry. Reactors, dryers, mills, and filling stations use clean-room procedures when switching lot runs. These steps show in the test results for every bag. We mark the control sheets with signatures and keep archives because memory alone—especially over years—won’t catch slow slips.

    User Feedback Shapes Each Batch

    Customers who buy straight from our plant bring tough demands. We’ve shared feedback loops with clients in Europe running cell culture media pilot tasks, as well as laboratories in Southeast Asia refilling stocks every quarter. Direct lines to process engineers on both sides mean we see almost every field problem first-hand.

    One research partner, working on diagnostic reagent kits, flagged non-dissolving specks in one batch, which turned out to be hard-to-spot process residue. Their feedback pushed us to upgrade to finer post-drying filters and double-rinse the packing tools. Batch reviews now include hands-on sediment checks on representative samples. Clients using our DL-Ornithine in fermentation have pointed out the need for fast flow in robotic feeders, so we added anti-clump steps post-milling, weighed best against flow rate, and kept the hydration spot checked to avoid overdrying.

    DL-Ornithine Storage Based on Our Practice

    Amino acid stability often hinges on storage. Through our own warehousing and collaboration with downstream users, we have learned the best outcomes come by shielding DL-Ornithine from moisture and direct heat. Packages are sealed in multi-layer polyethylene, then cased in cardboard drums. In our plant, we keep the drums at 15-25°C, with humidity under 60%. We avoid high racks close to skylights that can bake the contents over months. One summer, a batch stored too close to an aging heater picked up a faint yellow tint—small, but enough to trigger discards and remind us that these details can make or break quality assurance.

    Small labs and factories working off our product see the same stability, provided they follow tight sealing and cool, dry placement. We encourage partners to avoid decanting into unlined containers. Our shipping team monitors conditions during long transit, providing data loggers on major export deliveries by sea, so temperature spikes or humidity surges get caught early.

    Regulatory and Safety Observations

    We keep our files straight for local and international guidelines—our safety data book is built in-house for each batch. Our staff participate regularly in chemical handling and emergency response updates, which include not just spill control, but also proper labeling, handling, and disposal. We encourage users to refer to both our SDS sheet and local rules before scaling up use, and we always stand ready to support with technical insight backed by deep familiarity with official standards.

    For workers on the floor and users at the lab bench alike, DL-Ornithine behaves with low acute toxicity. Air and dust management remains a core focus in our plant, since powder can spread fast if a bag rips or a valve jams. Our personnel rotate through annual fit-testing for masks. All filling stations use local air capture to keep exposure to a minimum. We have taken cues from direct OSHA/REACH training, and these steps have translated directly into cleaner product and safer work shifts.

    The Role of DL-Ornithine in Industrial and Academic Progress

    Many university labs still use our DL-Ornithine in teaching and research. Years of feedback confirm that consistency and clear material identification help drive reproducible outcomes. We learned early that student projects often fail not for lack of effort, but for inconsistency in base chemical purity. These lessons guide not only how we produce, but also how we ship. Each drum comes with not just a typical certificate of analysis, but full run records. This “paper trail” shows real data, handwritten logs, and, when needed, a direct line for investigating odd results in the lab.

    Pharmaceutical companies and specialty chemical firms rely on DL-Ornithine building blocks for flow chemistry and multi-step syntheses. Our long-term clients stress fast response times and technical transparency. If a lot doesn’t track the theoretical purity, or if odd spots crop up on analysis, our phone always rings—and those calls don’t sit unanswered. We adjust, re-test, and, if needed, re-run. The partnership with these firms has steered several continuous improvements in reactor setup and drying lines, all aimed at guaranteeing every batch performs to textbook standards in commercial pipelines.

    DL-Ornithine from Our Perspective: Reliability and Accountability

    Outsiders sometimes view chemical manufacturing as little more than moving powder from bin to bag. For us, the story behind DL-Ornithine means knowing precisely how the molecule is built, checked, and moved. It shows in feedback we get from nutritional additive blenders, peptide synthesis labs, and fermentation engineers. The trust they show keeps us vigilant and keeps every pair of hands trained and retrained.

    We don't cut corners, and we don’t ship product unless it meets every data point from appearance to residue check. The values stamped on our test reports come from batches mixed, filtered, and bagged under one roof, by a team that knows each step affects the customer’s time and downstream work. Direct experience trumps speculation, which is why we stay as open as possible about what works and where improvements need to land.

    Continued Collaboration and Looking Forward

    Every new year, we revisit every detail—raw material source, batch yield ratios, machine calibration, and process validation—inviting feedback from current partners and prospects. The aim is not just to keep up with global demand or meet the latest certification standard, but to embody trust earned from years of shared success and mutual problem-solving.

    Our approach has always built on tough lessons. Suppliers who promise “cheap and cheerful” corners rarely stick around. We’ve replaced valves, reset controls after minor leaks, swapped out drum types, and, when feedback demands it, changed grading screens on the mill to add just the right level of flow. Through each small step, the product improves not only in test numbers, but also in the eyes of those who use it for mission-critical research or production.

    Your DL-Ornithine Journey Starts Here

    If DL-Ornithine is part of your process, our team stands ready to share experience, batch data, and field-proven solutions. Years of continuous learning, open dialog, and technical curiosity shape every lot we ship from our gate. We’re proud to offer more than a powder—we offer reliability, tested results, and the support of an experienced crew that knows the difference between specs on a page and results in the real world.

    In the hands of our customers, DL-Ornithine drives research, boosts yields, or simply acts as a stepping stone toward new discoveries. Reach out if you seek a product born of real practice and steady commitment, delivered straight from the source.