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Cresotic Acid

    • Product Name Cresotic Acid
    • Alias Cresol
    • Einecs 202-710-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    896161

    Chemical Name Cresotic Acid
    Other Names o-cresotic acid; 2-Hydroxy-3-methylbenzoic acid
    Molecular Formula C8H8O3
    Molar Mass 152.15 g/mol
    Appearance White to off-white crystalline solid
    Melting Point 162-164 °C
    Solubility In Water Slightly soluble
    Cas Number 118-66-3
    Density 1.28 g/cm³
    Pka 3.59
    Hazard Classification Irritant

    As an accredited Cresotic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Cresotic Acid, 500g, is packaged in a robust amber glass bottle with a secure cap and detailed hazard labeling for safety.
    Shipping Cresotic Acid should be shipped in tightly sealed, corrosion-resistant containers, clearly labeled according to hazardous material regulations. Store and transport it in a cool, well-ventilated area away from incompatible substances. Comply with local, national, and international shipping regulations, including proper documentation and emergency response information for the safe handling of hazardous chemicals.
    Storage Cresotic acid should be stored in a cool, dry, well-ventilated area, away from sources of ignition or heat. It must be kept in tightly closed containers that are clearly labeled and made of compatible materials. Protect from moisture and direct sunlight. Store separately from oxidizing agents, strong acids, and bases to prevent hazardous reactions. Use secondary containment if possible.
    Application of Cresotic Acid

    Applications of Cresotic Acid in Industrial Manufacturing

    Cresotic Acid serves as a specialized aromatic intermediate within multiple industrial sectors, supporting targeted production processes that require fine-tuned performance attributes and controlled impurity profiles. As a direct manufacturer, we supply Cresotic Acid for carefully defined applications, ensuring consistent quality and compliance with industry-specific regulations.

    1. Synthesis of Agrochemical Herbicides

    Manufacturers in the agrochemical sector utilize Cresotic Acid as a key intermediate for formulating select phenoxy herbicides. The controlled reactivity and ortho-para isomeric ratio provide stable scaffolding for etherification processes, facilitating scale-up of proprietary molecules like MCPA and MCPB. Process reliability relies on impurity control to avoid undesirable byproducts affecting field performance and environmental compliance.

    Industry compliance standards

    • FAO and WHO specifications for technical grade herbicide intermediates
    • European REACH registration for precursor substances
    • ISO 9001-certified quality management systems specific to crop protection chemicals

    Typical usage ratio

    • 5–18% of total batch weight for phenoxy herbicide synthesis, ratio adjusted based on target molecule and desired impurity threshold. Adjustments depend on chain extension and side group reactivity.

    Downstream process integration

    • Introduced during esterification or etherification response, directly upstream of halogenation or neutralization steps.
    • Dosed after solvent preparation and pH adjustment to maintain catalyst efficiency throughout batch processing.

    Final product types

    • MCPA (2-methyl-4-chlorophenoxyacetic acid)
    • MCPB (4-(4-chloro-o-tolyloxy)butyric acid)
    • Related phenoxyalkanoic acid herbicides

    2. Industrial Dye and Pigment Production

    Dye and pigment manufacturers react Cresotic Acid with organic coupling partners in azo and anthraquinone colorant synthesis. Reliable color shade and purity start with consistent precursor purity and correct isomer selection. Production teams must precisely sequence the sulfonation and diazotization steps to avoid incomplete reactions and ensure chromophore stability.

    Industry compliance standards

    • OEKO-TEX® Standard 100 for dyestuff input chemicals
    • REACH Annex XVII and XIV for limiting restricted aromatic impurities
    • ZDHC Manufacturing Restricted Substances List (MRSL) for textile chemicals

    Typical usage ratio

    • 7–12% relative to total dye mass; ratio modified by molecular weight and target absorbance strength. Fine-tuned to control shade depth and cost efficiency.

    Downstream process integration

    • Fed during initial coupling reactions, following base neutralization and before the chromophore-forming condensation stages.
    • Used to stabilize intermediate color forms prior to crystallization or spray drying.

    Final product types

    • Direct azo dyes for cellulose fibers
    • Anthraquinone-based disperse dyes for polyester
    • Specialty pigments for printing inks
    • Coloring agents for plastics

    3. Pharmaceutical Intermediate Manufacturing

    API manufacturers receive Cresotic Acid for synthesis routes of select antipyretic and analgesic agents. The ortho-methylphenol structure enables specific substitutions and controls unwanted positional isomers, integral for meeting pharmacopeial monographs. Trace impurities and heavy metals must be documented and limited according to regionally relevant pharmacopeial purity criteria, requiring vigilant batch certification.

    Industry compliance standards

    • United States Pharmacopeia (USP) for API intermediates
    • European Pharmacopoeia (Ph. Eur.) monographs applicable to synthetic starting materials
    • Current Good Manufacturing Practices (cGMP) per ICH Q7

    Typical usage ratio

    • 3–10% by weight in initial coupling or condensation steps, with actual levels defined by target synthetic pathway and downstream derivatization protocols.

    Downstream process integration

    • Utilized after solvent selection and catalyst charging, often introduced just before closed-system methylation or amidation reactions in multi-step synthesis.
    • Supports positional selectivity during core ring functionalization prior to crystallization or salt formation.

    Final product types

    • Acetaminophen (paracetamol) intermediates
    • Ibuprofen precursor compounds
    • SARMs and non-opioid analgesic intermediates

    4. Antioxidant Additive Manufacturing for Polymers and Lubricants

    Specialty additive producers incorporate Cresotic Acid as a core building block in the production of hindered phenol-type antioxidants. These stabilizers counteract thermo-oxidative degradation in plastics and industrial oils. Batch-to-batch consistency in isomer and residual metals is critical, as variations may trigger premature yellowing or reduced oxidation resistance in automotive or packaging end uses.

    Industry compliance standards

    • ASTM D6386 for polymer antioxidants
    • FDA 21 CFR 178.2010 for indirect food contact additives in polymers
    • EN 71-3 safety standard for toy plastics

    Typical usage ratio

    • 0.2–2.5% of total additive system mass, depending on polymer matrix and targeted stability hours. Adjustments based on specific base oil or resin type.

    Downstream process integration

    • Charged into reaction vessels prior to alkylation or condensation with acetone or formaldehyde for antioxidant synthesis.
    • Precisely metered during compounding of masterbatch or additive concentrate to assure uniform distribution.

    Final product types

    • Phenolic antioxidants for polyethylene and polypropylene
    • Lubricant oil stabilizers
    • Masterbatch antioxidants for extrusion processes
    • Heat-resistant packaging films

    5. Wood Preservative and Antifungal Agent Manufacturing

    Leading formulators in the timber treatment sector leverage Cresotic Acid for synthesis and blending of phenolic wood preservatives. Its bacteriostatic and fungistatic activity depend on isomer composition and minimal residual solvent levels. Production must manage emission controls and meet mandatory composition criteria defined in treated wood standards.

    Industry compliance standards

    • EN 1390 and AWPA P8 for wood preservative composition
    • EPA FIFRA requirements for active ingredient registration (United States)
    • BPR Regulation (EU) No 528/2012 for biocidal products

    Typical usage ratio

    • 3–12% w/w in concentrated preservative blends, variable with timber density and local environmental exposure classification.

    Downstream process integration

    • Blended into water-borne or oil-borne concentrates post-solubilizer addition and before emulsion or solution adjustment.
    • Monitored across blending tanks to track homogeneity prior to filling into bulk treatment systems.

    Final product types

    • Oil-based and water-based wood preservatives
    • Antifungal coatings for outdoor wood structures
    • Deck and fence treatment chemicals

    6. High-Performance Resin and Adhesive Systems

    Producers of specialty resins and adhesive binders use Cresotic Acid for controlled ring modification, conferring enhanced chemical resistance and tailored flexibility in phenolic and epoxy resin systems. Fine control over isomeric distribution and residual solvents helps maintain curing speed and prevents phase separation during storage and application.

    Industry compliance standards

    • ASTM D3638 guideline for electrical insulation resins
    • UL 94 flammability requirements for adhesive applications
    • ISO 9001-certified quality control systems in polymer chemistry

    Typical usage ratio

    • 2–7% by weight for batch resin or adhesive, with ratio based on required glass transition temperature (Tg) and targeted mechanical properties.

    Downstream process integration

    • Added post-polyol blending but before curing agent injection in resin kettles.
    • Mixed into adhesive prepolymers to balance crosslinking rate and viscosity before final hardener addition.

    Final product types

    • Chemically resistant phenolic resins for molded parts
    • Structural adhesives for electronics assembly
    • Composite binder systems for construction materials

    Free Quote

    Competitive Cresotic Acid prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

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    Certification & Compliance
    More Introduction

    Cresotic Acid: Experience, Application, and How Our Manufacturing Approach Makes a Difference

    Years in Cresotic Acid Production: Practical Insights from the Source

    Every kilogram of cresotic acid that leaves our gates reflects countless hours in development, care, and field experience. Our team has specialized in the production of cresotic acid for decades, putting us in a position to see, daily, how the right approach in manufacturing changes the reliability of the chemical itself. In contrast to companies focused only on distribution, we see the full lifecycle—from raw material procurement to shipment—shaping how the product functions and how it holds up to the diverse demands of our customers.

    Understanding Cresotic Acid: Composition and Model Information

    This compound, known among chemists as hydroxy-methylbenzoic acid, exists in several distinct isomeric forms. What matters most to users is that each isomer brings its own strengths—most commonly, we manufacture and supply ortho-cresotic acid and para-cresotic acid, responding to specific customer requirements rather than standardized one-size-fits-all models. These substances differ from other carboxylic acids both in reactivity and in how they react under heat or in solvents.

    Inside our facilities, we maintain purity specifications above 99% for all pharmaceutical and fine chemical grades. Purity like this means more predictable performance in end-use. By taking control of the entire purification process, we keep heavy metals, moisture, and organic impurities far below internationally accepted limits. Our product is typically supplied as white to slightly off-white crystalline powder. Some grades may carry a faint odor, a natural characteristic of high-purity aromatic compounds rather than a sign of contamination.

    Our isomeric separation lines handle ortho- and para-cresotic acids as different products, depending on downstream demand. While the differences seem minor in textbooks, the structural orientation makes a real impact in synthesis. For example, ortho-cresotic acid finds heavier use in dye intermediates, and para-cresotic acid proves more effective in some pharmaceutical actives. Quality control takes place in-house through HPLC and titration, producing certificate of analysis documents that genuinely match each output batch—never generic.

    Why Our Approach Builds Better Cresotic Acid

    Many chemical producers rely heavily on bulk intermediates or less refined raw materials to cut costs. Over time we discovered that this philosophy brings surprises—not the good kind—for users down the line. We rigorously test incoming materials before they ever see the reactor, ensuring that each lot meets our internal guidelines long before production even begins. If the incoming stock is subpar, we either purify it ourselves or reject it outright. This quality-first approach does more than satisfy paperwork demands—it saves our clients from headaches in their own blending or synthesis.

    Our plant runs on closed-loop batch reactors with precise temperature and agitation control. Through experience, we've noticed temperature ramp rates and agitation speeds are not trivial. These factors determine yield but also influence crystal habit and the nature of trace impurities. Early on, we invested in reactor automation, which grants tighter control over conditions, less batch variability, and greater workplace safety. Our chemists resolve problems as they arise, not after a batch leaves. This hands-on management differs starkly from resellers who might only see the product after it's drummed up and labeled.

    Packaging forms include fiber drums with polyethylene liners, smaller HDPE kegs, and tailored bulk packaging for larger clients. We chose these only after learning how moisture ingress during storage changes the handling characteristics and shelf-life. Over-tight packing can trap trace moisture; too loose and caking or air contamination becomes a concern. Our customers report real-world shelf lives exceeding two years when stored correctly.

    Direct Knowledge from Day-to-Day Performance

    As a manufacturer, we take daily calls from users whose requirements constantly evolve. This direct stream of feedback is what keeps our process grounded and not locked in the theoretical. Some customers need cresotic acid for resins, where melt-point consistency is non-negotiable. Others build it into corrosion inhibitors or as a coupling agent in plasticizers, where trace sulfur or iron levels can undo a full production run. By integrating feedback right back into our plant-level adjustments, we protect repeat buyers from ever having to revalidate or recalibrate their formulation because of drifting specs.

    We track lot performance in customer processes, watching for variables like filtration speed, solubility, and downstream conversion rates. If a shipment underperforms in terms of color or dissolves more slowly in end-use solvents, we trace the lot back through our own logs and, if warranted, rerun the batch. Many times, these cases result from subtle differences in crystallization—something that can only be managed at the manufacturing level. Distributors have little to say about production parameters, but being deeply invested in chemistry lets us shorten troubleshooting cycles.

    Comparison with Other Aromatic Acids and Commercial Alternatives

    Cresotic acid stands apart from the more common benzoic or salicylic acids in both chemical activity and industrial behavior. The substituted methyl and hydroxyl groups influence not just acidity but participation in condensation or nitration reactions. From our own data, cresotic acid displays mild hydrophobicity compared to its parent compounds. This property influences its success in applications such as paint hardeners or adhesives, where excessive moisture incompatibility can ruin a batch.

    Cresotic acid also competes with cresols and cresylic acids, especially in resin or phenolic syntheses. While all derive from similar aromatic chemistry, cresotic acid contains both a carboxylic and a hydroxyl group, setting up more complex reactions with components like aldehydes or formaldehyde. Over the years, clients have chosen cresotic acid over cresol in cases where thermal stability and acid function make a difference in product longevity. We have seen resin manufacturers achieve higher molecular weight polymers and sharper curing profiles by substituting cresotic acid for less pure or less defined cresylic blends.

    Unlike more generic phenolic acids, cresotic acid in our experience offers a lower tendency toward oxidation during storage, provided the environment remains cool and dry. This stability impacts cost-effectiveness for end users, who face fewer losses from batch spoilage. In terms of safety profile, cresotic acid—while requiring ordinary chemical hygiene—presents fewer volatility problems than pure cresols, leading to safer working conditions in busy facilities.

    Applications as Seen from a Manufacturer’s Point of View

    From our production floors, the demand for cresotic acid falls into distinct industries, each with its own nuances. Dye producers request ortho-cresotic acid for azo dye intermediates, relying on its selectivity in coupling reactions to deliver cleaner color and more stable shade development. Pharmaceutical companies approach us with tight impurity guidelines because they use cresotic acid to synthesize active components or as a starting point for fine-chemical intermediates in antihistamines or anti-inflammatories.

    We track frequent orders from resin and adhesive companies, who incorporate cresotic acid to modify glass transition temperatures or to improve crosslinking in phenolic polymers. Compared to low-purity or mixed-isomer sources, our material delivers repeatable performance—a value supported by our long-term customer relationships rather than marketing claims. Customers in water treatment and corrosion inhibition industries value the chelating ability, using it to stabilize formulations prone to metal-catalyzed degradation.

    What stands out from hearing directly from customers is that no two applications are identical, and success always rides on consistency. Recently, we worked with an adhesives formulator who struggled with inconsistent flow times due to off-spec supplier material. After a pilot run with our cresotic acid, their process stabilized—saving them both labor and raw material cost every quarter.

    Sourcing: The Difference Manufacturer Involvement Brings

    Global supply chains throw curveballs—whether it’s shipping delays, regulatory changes, or surges in raw material prices. By owning our production facility, we control our ability to ramp up or pivot production to keep sales orders moving. We’ve maintained open lines with upstream vendors for decades, which has smoothed over shortages that would have stalled production or forced lesser material onto our customers.

    Custom orders for specific isomers or unusual impurity specifications come directly to our technical team. For example, specialty polymer clients sometimes require cresotic acid with ultra-low chloride or heavy metal content—needs we address by tightening the purification process rather than telling customers to accept “industry standard” grades.

    Because our expertise starts at the chemical reactor, not a spreadsheet, we know how small changes upstream—like reaction time or solvent fraction—affect how cresotic acid behaves in real applications. This level of insight means problems get solved on the production floor, not at the customer’s expense. Regular audits, product traceability, and continuous process records back up every shipment we supply, giving users a foundation for compliance and safe handling.

    Supporting Reliable, Transparent Chemical Sourcing

    Working as a manufacturer, we realize that communication stands as vital as raw material sourcing or reactor operation. Clients ask about everything from reach registration to food-contact compliance, and we review each requirement in light of real-world production records. Our team addresses questions with practical, detailed responses, sharing direct data rather than generic claims.

    Many years ago, some users felt forced to switch suppliers every six months, forever testing new material. Our company approach solves this cycle not by offering a one-size-fits-all chemical, but by building flexibility into purification and testing. If formulation requirements change, we talk directly to the laboratory staff or the plant manager—not through three levels of traders. We adjust product characteristics with new process runs or lab-scale batches, maintaining confidentiality and security for all involved.

    Our clients in regulated industries receive support with regulatory documentation, process change notifications, and full batch traceability. This kind of hands-on involvement is how we build the trust that keeps production managers coming back season after season.

    Quality, Traceability, and Risk Management from a Producer’s View

    Years of hands-on chemistry teach hard lessons. Even small deviations in production can trigger batch failures or trigger recall risks for downstream users. As manufacturers, we record every process variable, from raw ingredient log-in to final particle size. Batch numbers run sequentially and trace directly to reactor and worker data, making problem-solving immediate and reliable.

    Our technical support staff crosses over into the R&D lab and works with customers’ own technical staff. If a buyer’s downstream process shifts, we evaluate how our cresotic acid interacts with new operating parameters, solving problems before they scale up. For clients with strict regulatory obligations or those working in countries with evolving chemical policy, our internal logs and open-book operating style become not just a convenience but a necessity.

    Market conditions change faster than ever. As a producer directly involved in every process, from raw material inspection through shipment, we keep batch-to-batch variations low and recognize early warnings of shortage or process drift. This vigilance pays off as recurring business, open communication, and lower risk for everyone in the chain.

    Future Direction of Cresotic Acid Manufacturing

    Demand continues to shift as new end-markets develop. Applications in advanced materials, specialized pigments, and pharmaceuticals put tighter demands on both product purity and process transparency. We invest in new reactor controls and analytical equipment, because our customers’ requirements drive the improvements—not marketing trends or catalog copy.

    Environmental and workplace safety keeps climbing as a priority for buyers worldwide. We already meet or exceed prevailing standards with sealed systems, in-house emissions treatment, and zero-discharge handling. By building these protections into design—not as afterthoughts—we meet rising global expectations without disruption to buyers.

    On the technical front, we explore new separation and purification methods, including simulated moving bed chromatography and solvent-free crystallization. Improvements yield not only purer cresotic acid but also simplified downstream processing for our clients. As chemistry moves forward, we maintain direct control of our process and hands-on involvement with each new requirement.

    Our ownership of the manufacturing process—combined with consistent attention to customer feedback and regulatory trends—creates value in every batch. In sum, working directly as a producer means more than just chemical supply; it means real partnership in every kilogram shipped, every process improved, and every challenge solved alongside our clients.