|
HS Code |
441975 |
| Chemical Name | Citramalate |
| IUPAC Name | 2-methyl-2-hydroxybutanedioic acid |
| Molecular Formula | C5H8O5 |
| Molar Mass | 148.115 g/mol |
| CAS Number | 525-97-5 |
| Appearance | White crystalline solid |
| Solubility in Water | Soluble |
| Melting Point | 160-165°C |
| pKa | 3.45 (first), 5.84 (second) |
| Synonyms | 2-Methylmalic acid, DL-Citramalic acid |
| Boiling Point | Decomposes before boiling |
| Density | 1.59 g/cm³ |
| Odor | Odorless |
As an accredited Citramalate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of Citramalate, supplied in a sealed, amber glass bottle with tamper-evident cap and chemical hazard labeling for laboratory use. |
| Shipping | Citramalate is shipped in tightly sealed containers made from compatible materials, such as HDPE or glass, to prevent contamination and moisture exposure. Packaging complies with relevant safety regulations, including labeling and transport documentation. Containers are kept in a cool, dry location and handled with proper protective equipment to ensure safe delivery. |
| Storage | Citramalate should be stored in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers. Keep the container tightly closed and clearly labeled. Store at room temperature, avoiding excessive heat and moisture to prevent degradation. Use proper personal protective equipment when handling to ensure safety and minimize exposure. |
Applications of Citramalate in Industrial ManufacturingCitramalate plays a pivotal role as an intermediate and functional additive in several specialized industrial sectors. The following application scenarios reflect real-world downstream integration by major manufacturers, supported by known standards and granular processation details. As a direct chemical raw material producer, we maintain decade-long partnerships with regulated industries, ensuring compatibility across complex scaling, regulatory audits, and finished product QC. 1. Biodegradable Plasticizer Production for BiopolymersBiopolymers manufacturers use citramalate as a renewable monomer and plasticizer in polyhydroxyalkanoates (PHAs) and thermoplastic polyesters. Integrating citramalate adjusts the flexibility, hydrophilicity, and compostability of the final polymer, replacing fossil-derived co-monomers. Manufacturers typically initiate the process at the bioreactor fermentation stage, where citramalate concentration directly affects polymer chain characteristics. End-use products feature tuned degradation rates governed by the specific ratio added mid-process. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
2. Chiral Intermediate for Pharmaceutical SynthesisSeveral API and advanced intermediate facilities use citramalate as a chiral building block. The dicarboxylic acid structure serves in enzymatic and chemical synthesis routes for beta-amino acids, statin derivatives, and other linear-chain APIs. Compliance steers raw material selection: production must comply with GMP and avoid contamination at isomeric separation stages. Tier-1 manufacturers frequently monitor in-process purity by HPLC to meet API precursor standards. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Flavor Modulation Agent in Food Ingredient ManufactureLeading food ingredient plants incorporate citramalate as a natural acidulant and flavor enhancer targeting non-citrus acidic notes in beverages and processed foods. Application demands adherence to international additive regulations and clear declaration on compound ingredient lists. Manufacturers modulate the pH and acid profile during late-stage blending; this maintains product consistency and shelf stability, especially in clear beverages. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Metal Chelation in Industrial Cleaning FormulationsCorporate cleaning chemical producers select citramalate as an environmentally responsible chelating agent to boost the removal of limescale, mineral residues, and heavy metals from sensitive machinery. Regulatory responsibility demands strong documentation and compliance with REACH and environmental labeling codes. Industrial-scale users titrate dosage against local water hardness and specific metal load, ensuring both high cleaning efficiency and safe discharge profiles. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
5. Precursor for Bio-based Acrylate Solvents and ResinsSolvent and resin manufacturers use citramalate as an eco-sourced precursor for novel acrylate derivatives. Its structure enables conversion into high-purity monomers supporting low-VOC coatings. Process engineers implement rigorous conversion control at the reactor, optimizing intermediate purity for downstream polymerization. Finished applications require compliance with both worker safety and green chemistry specifications, especially for lacquers and paper coatings. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
6. Additive for Nutraceuticals and Food SupplementsSelect nutraceutical producers integrate citramalate for its organic acid profile and natural occurrence, manufacturing non-citrate mineral tablets and fortification blends. Material safety and allergen-free sourcing remains critical to market these products as compliant with sports and health supplements legislation. Blending occurs during dry granulation or after microencapsulation steps, directly impacting solubility and bioavailability in the finished batch. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
|
Competitive Citramalate prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.
We will respond to you as soon as possible.
Tel: +8615371019725
Email: admin@sinochem-nanjing.com
Flexible payment, competitive price, premium service - Inquire now!
Years ago, the demand for efficient, sustainable chemical building blocks pushed our research team to dig beyond the obvious. Through hands-on experiments, trial, and no shortage of failed batches, Citramalate began taking form in the pilot plant, long before the rest of the industry eyed its potential. As chemists surrounded by reactors and glassware every day, we see where common intermediates hit limitations—solubility, reactivity, compatibility. Citramalate offers an answer that stands out from the pack.
Our flagship Citramalate model starts as a pure, crystalline white powder. We put years into refining a process that produces high yield without contamination. The process uses renewable raw materials and avoids phosgene or other hazardous reagents. Each lot meets a purity level of at least 99 percent by HPLC. Moisture content stays well below 0.5 percent, which greatly improves storage stability. In practical use, that means less caking in the drum, easier handling on a factory line, and minimal clumping during transfer.
Our R&D team insisted that particle size influences behavior in downstream use. For our standard model, average particle diameter lands between 70 microns and 110 microns. No gritty aggregation, no excessive dust. That matters for operators dumping bags into mixers, for lines relying on consistent dosing, and for anyone figuring out flow rates on a new process or application.
Before offering Citramalate, we validated it in our own product lines. We used it as a synthesis intermediate for specialty ester production, where it delivered a clean reaction profile every time. No mystery by-products. No stubborn color bodies; final yields reached the planned targets batch after batch. That reliability saved us real money in purification step costs. We’ve also swapped out older chelators for Citramalate in metal ion remediation protocols—citramalate’s two carboxylic acid groups and an extra methyl branch create a stability profile unmatched by citric acid or glutarate. It delivers steady chelation with transition and rare earth metals.
Formulators who handle organic acids know some grades bring a lingering smell, sticky fines, or uneven solubility. Our Citramalate dissolves rapidly in water, even at cooler room temperatures. We’ve measured dissolution at 25 degrees Celsius and no undissolved solid remains after stirring for just a minute. That quick dissolution opened new possibilities for reactive blends and time-sensitive formulations that previously depended on other, less reactive acids.
We have customers from flavors and fragrances to specialty polymers who rely on Citramalate for its raw chemical profile. In bio-based polyesters and polyamides, Citramalate’s backbone gives improved flexibility and transparency in finished films. That isn’t just a theoretical claim; we’ve run parallel tests with samples using glutaric acid, citric acid, and succinic acid as comparators. The results show Citramalate consistently delivers superior elongation and prevents yellowing after UV exposure. Polymer chemists who walk the same factory floors appreciated real numbers—so did we.
Fermentation specialists come to us for Citramalate as a metabolic intermediate. Microbial cells break it down efficiently, and it avoids the metabolic bottlenecks sometimes seen with closer structural analogs. In flavor enhancement, food technologists use it as a pH regulator, taking advantage of its dual-acid profile. Edible coatings using Citramalate resist spoilage and interior browning, especially in post-harvest fruit treatments. These results stem from technical trials at our own pilot plant, not just literature reviews.
You don’t achieve something useful in chemical manufacturing by repeating competitors. Before commercializing, we ran side-by-side trials with various grades of citric acid, malic acid, and maleic acid. Each one brings unique chemistry, but Citramalate stands out in thermal stability testing—less degradation at elevated temperatures, even after 48 hours at 80 degrees Celsius. That helps in applications like thermoset resins, powder coatings, and specialty adhesives needing better heat resistance.
Handling also matters in large-volume production. Citric acid powders tend to compact under heavy weight. Reprocessing citric acid after long-term storage is a familiar headache—agglomerated blocks slow down operators and production. Citramalate’s unique crystalline morphology resists that compression. Drums and bags stored for six months open with material still loose, easy to pour, and never blocks hoses or augers.
Too much of the industry focuses on numbers without respecting the daily challenges facing plant staff. Our own operations team noticed less dust during loading with Citramalate. The dust reduction results in lower respiratory risks, fewer PPE requirements, and easier workspace cleaning. This difference comes from both the particle engineering and the way moisture is controlled during packaging. It sounds small until you handle hundreds of drums and recognize that cleanup hours—and maintenance headaches—drop.
Scale-up specialists always prefer a predictable flow profile. We spent months optimizing our Citramalate’s pour rate in both gravity bins and vibratory feeders. Consistent, repeatable flow keeps automated feeds running smoothly, reducing shut-downs and manual intervention. These hours saved represent real returns, not just smoother PowerPoint presentations.
Working hands-on with Citramalate, we appreciate its low odor, mild corrosivity, and non-hygroscopic nature. Unlike many comparable acids, Citramalate does not aggressively attack stainless or common process plastics, even at higher concentrations. We keep packaging moisture-tight, not just for purity, but to avoid unnecessary spoilage or caking over months. On our own shelves at the plant, Citramalate holds up well for at least two years in the right conditions—a dry warehouse and sealed drum. No ambient degradation and no loss in reactivity, even after long-term QA checks.
We have invested in full traceability, batch-level analytics, and continuous in-process QC. Every lot we produce comes stamped with an ID that connects straight back to source materials, reactors, analytical test results, and operator sign-offs. Quality is tracked at every step, so any abnormality gets flagged and pulled before it leaves our property. Customers who visited our site saw our real-world approach to batch control and left with more trust in the material.
Throughout the years, customers approach us not just for a product, but for technical advice rooted in experience. We share process improvements learned from scaling up our own reactions. We offer guidance on integrating Citramalate into new and legacy processes without chasing after endless reformulations.
Universities and industrial partners use our Citramalate in bioprocesses where microbial sensitivity is critical. Our material passes bioburden and endotoxin screening, meeting pharmaceutical and food industry expectations. For those developing new catalysts or testing polymer blends, we provide clear, usable data direct from our in-house application lab—solubility curves, reactivity under various pH and temperature regimes, and performance under stress testing.
We also keep our documentation current, not because a regulator asks, but because it makes operations smoother for everyone. We include constantly updated COAs and full lot documentation so every batch integrates seamlessly into production records.
Discussions about environmental responsibility often settle into vague claims. We approach sustainability as scientists and manufacturers, not marketers. Our Citramalate relies on fermentation-based feedstocks instead of petrochemicals. Energy needed for the conversion process has dropped by more than 30 percent in the past five years due to process improvements. Waste generation is minimized by reclaiming mother liquors for in situ pH adjustments in other lines.
Internal life cycle analyses support our claim: Citramalate production at our facility reduces greenhouse gas emissions by at least 20 percent compared to petro-based analogs, measured from raw material input to final packaging. No hazardous wastewater stream leaves the site; all water is treated and reused in cooling or boiler systems. For customers with zero-waste targets of their own, our team provides additive environmental data along with technical specs.
Working with commodity acids often means trading consistency for price. We’ve been there ourselves, sat through the procurement meetings, and chased suppliers after delayed shipments or supply chain hiccups. That experience shapes the way we manufacture and deliver Citramalate. We keep the raw material supply local and put real energy into logistics partnerships. Every shipment gets verified for quality and timing.
The price may be higher on paper than a low-grade acid, but operators tell us Citramalate’s processing reliability pays off in less downtime, less waste, and fewer surprises on the production floor. Even for large-scale operations producing plastics or polymers at thousands of tons per year, those savings are hard to ignore.
Customers in fine chemical manufacturing, agrochemicals, and food tech count on us to supply what their process needs, not just what’s cheap or easy to find. They call when a batch takes an unexpected turn, and we provide the advice they need because our lab staff use the same equipment and run many of the same reactions every week.
Our manufacturing floor isn’t run by algorithms or remote control—instead, it is guided by decades of experience and on-the-ground intuition. Feedback from packaging handlers led us to redesign our bagging line to further reduce material loss and improve seal integrity. After a customer noted static charge buildup slowing their dosing process, we adjusted moisture control procedures and found that our upgraded blend eliminated sticking issues.
In any area where Citramalate faces challenges, whether it’s blending into viscous slurries or maintaining purity under shipping stress, our team addresses it directly. We test product in customer applications, identify root causes, and refine process parameters so the next batch runs better than the last. This feedback loop makes our Citramalate more robust year after year.
We aren’t a warehouse repackaging drums from anonymous suppliers. Down the hall from our customer service office sits the process control room. Every week, process engineers, plant chemists, and logistics specialists review batch performance, bottleneck issues, and customer feedback. We maintain reserve manufacturing capacity, so last-minute changes in schedule or urgent requests can be handled without cutting corners.
Our commitment to supply reliability comes from our own experience managing emergencies. After storms closed transport routes, our inventory system and direct shipping operations kept customers in product—no panic, no substitutions. Other manufacturers sometimes scramble to find alternatives when upstream supplies dwindle; by owning the process end-to-end, we avoid these disruptions.
Demand for molecules like Citramalate only grows as industries shape toward greener, safer, and smarter chemistry. Our product fits seamlessly into this movement. As regulations tighten and the call for alternatives to high-impact chemicals grows louder, Citramalate stands ready with a proven track record. Our technical data come from hands-on batch runs, not desktop studies. We are ready to provide samples, technical support, and anything needed to get trials started.
Having worked for years in the business, we understand the cost and risk of changing raw materials. We support transitions by offering technical guidance based on our own plant experience, real application test results, and deep coordination with client engineers and chemists. We believe Citramalate, built on trust, consistency, and top-end process control, delivers true value to every corner of the chemical industry—from synthesis labs to high-output production floors.
As long as the world needs high-performance, sustainable chemical intermediates, we’ll continue refining our Citramalate with that goal in mind. Our plant is open to collaborations, site visits, and real conversation. Everything we know comes not from theory, but from hands-on, boots-on-the-ground efforts. We invite you to discover what Citramalate can bring to your own process, and join us on the journey toward better chemistry and better results.