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Cis-Miyabenol C

    • Product Name Cis-Miyabenol C
    • Alias Vitisin B
    • Einecs NA
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    334076

    product_name Cis-Miyabenol C
    CAS_number 95402-67-6
    molecular_formula C42H32O12
    molecular_weight 728.69 g/mol
    appearance Off-white to pale yellow powder
    purity ≥ 98% (HPLC)
    solubility DMSO, Methanol
    storage_temperature -20°C
    source Natural plant polyphenol
    chemical_class Stilbenoid dimer
    IUPAC_name (2R,3R,8R,9R)-2,8-bis(4-hydroxyphenyl)-3,9-bis(3,5-dihydroxyphenyl)-2,3,8,9-tetrahydro-1,10-dioxaanthracene-6,7,14,15-tetrol
    synonyms cis-Miyabenol C, cis-ε-Viniferin Dimer

    As an accredited Cis-Miyabenol C factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Cis-Miyabenol C is packaged in a 10 mg amber glass vial, tightly sealed, with detailed labeling for chemical identification and storage instructions.
    Shipping Cis-Miyabenol C is securely packaged in sealed, inert containers to prevent contamination and degradation. It is shipped in compliance with international chemical transport regulations, typically under controlled temperature conditions. All shipments include appropriate labeling, safety documentation, and handling instructions to ensure safe and regulatory-compliant delivery to the destination.
    Storage Cis-Miyabenol C should be stored in a tightly sealed container at -20°C, protected from light and moisture. It should be kept in a dry, cool, and well-ventilated area, away from sources of ignition and incompatible materials. Proper labeling and chemical safety protocols should be observed to maintain stability and ensure safe handling.
    Application of Cis-Miyabenol C

    Applications of Cis-Miyabenol C in Industrial Manufacturing

    Cis-Miyabenol C is a polyphenolic compound extracted and refined under GMP controls, with advanced purity for global B2B supply. Our technical grade supports production operators in pharmaceutical synthesis, nutraceutical formulation, and cosmeceutical innovation, meeting the evolving quality and compliance needs of regulated industries.

    1. Pharmaceutical Intermediate for Anti-inflammatory APIs

    Pharmaceutical manufacturers use cis-Miyabenol C as a phenolic intermediate in the synthesis of targeted anti-inflammatory drug substances, particularly where oxidative modulation pathways are critical. In these operations, integration occurs at the early-stage reaction vessel step, enabling the downstream creation of more complex molecules. Consistency in purity and impurity profile is crucial for batch traceability and regulatory submission. The raw material supports both preclinical and commercial scale processes, with full audit trail documentation provided to meet pharmaceutical QA requirements.

    Industry compliance standards

    • ICH Q7A Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • US FDA 21 CFR Part 211 for Drug Product GMP
    • European Pharmacopoeia Monographs
    • US Pharmacopeia (USP) Reference Standards

    Typical usage ratio

    • Weighted as 0.1%–3%, adjusted according to molecular yield and product impurity thresholds;
    • Optimization depends on specific target molecule and downstream synthetic steps;
    • QC labs validate inclusion ratio throughout clinical to final commercial scale-up.

    Downstream process integration

    • Dissolution in ethanol or suitable organic solvent in upstream reactors;
    • Chemical coupling with ketone or amide functional reactants;
    • Filtration and recovery protocols for post-reaction purification;
    • Analytical verification prior to further chemical transformation.

    Final product types

    • Bulk APIs (Active Pharmaceutical Ingredients) for use in anti-inflammatory drugs
    • Oral solid doses (tablets/capsules)
    • Injectable solutions
    • Pharmaceutical intermediates for licensed CMO clientele

    2. Nutraceutical Supplement Ingredient

    Nutraceutical producers incorporate this compound as a botanical antioxidant in dietary supplement blends, with full traceability for health claim substantiation. It finds use in plant-extract tablets, capsules, and functional foods, demanding microbiological and heavy metal compliance due to user ingestion. Blending protocols require controlled dry mixing and granulation to ensure even distribution, targeting consumer wellness applications. Supply partners must maintain rigorous batch analysis and supply chain transparency to support successful new product registration.

    Industry compliance standards

    • ISO 22000:2018 Food Safety Management System
    • FSSC 22000 Certification Programs
    • China Food Additive Standards (GB)
    • Dietary Supplement Health and Education Act (DSHEA, USA)

    Typical usage ratio

    • Typically 10–120 mg per daily serving in finished dosage forms;
    • Percentage by blend mass: 0.05%–1.0%, determined by regional regulatory limits;
    • Analytical verification by HPLC prior to packaging.

    Downstream process integration

    • Direct addition to mixing and compounding stage for powder blends;
    • Wet or dry granulation prior to tablet compression or encapsulation;
    • Coating step to control release profile in multi-layer tablets;
    • Integrated QA/QC checks for active compound content.

    Final product types

    • Botanical supplement tablets
    • Vegetarian capsules
    • Functional food powders
    • Premix sachets for wellness beverages

    3. Cosmeceutical Active in Advanced Skin Care Formulations

    Cosmetic and personal care manufacturers adopt cis-Miyabenol C as a specialized active in anti-aging, brightening, and antioxidant skin formulations. It enters at the high-shear mixing stage after water-soluble and oil-phase actives are pre-blended. Regulatory submissions require accurate INCI documentation as well as demonstrated purity and safety data for rapid product testing approval. Quality-focused formulators perform stability testing to adapt pH and emulsifier systems, securing both immediate and extended shelf life for global distribution.

    Industry compliance standards

    • EU Cosmetics Regulation EC No. 1223/2009
    • US FDA Cosmetic Labeling and Good Manufacturing Practice Guidelines
    • ISO 22716:2007 Cosmetics GMP
    • Health Canada Cosmetic Ingredient Hotlist

    Typical usage ratio

    • Commonly 0.02%–0.3% w/w in finished creams and serums;
    • Concentration dependent on formula viscosity and desired antioxidant capacity;
    • Performance testers determine ideal levels via accelerated stability trials.

    Downstream process integration

    • Introduced as solution or dispersion in post-heating cooling phase;
    • Solubilization with glycols for uniform distribution in emulsions;
    • Microbial challenge tests after batch mixing;
    • Filling under inert or nitrogen conditions for high-end packaging.

    Final product types

    • Facial serums
    • Day and night creams
    • Sheet mask solutions
    • Anti-aging emulsions for professional SPA use

    4. Plant-Derived Polyphenol for Food Preservative Systems

    Food manufacturers utilize cis-Miyabenol C in specialty preservative blends aimed at extending shelf-life in high-value products prone to oxidative spoilage. Incorporation typically occurs during formulation of oil-rich or ready-to-eat items, leveraging the antioxidant properties for color and aroma retention. Downstream process demands include stringent allergen and trace contaminant analysis. Quality assurance documentation is mandatory to ensure compliance with global clean-label food standards and market access requirements.

    Industry compliance standards

    • FAO/WHO Codex Alimentarius General Standard for Food Additives (GSFA)
    • US FDA CFR 21, Part 172, Food Additives Permitted for Direct Addition to Food
    • EU Regulation (EC) No. 1333/2008 on Food Additives
    • China National Food Safety Standard GB 2760

    Typical usage ratio

    • Added as 30–200 ppm in finished food mass, adjusted to product fat content and water activity;
    • Blending trials establish minimum effective dose for regulatory approval in target regions;
    • Periodic laboratory checks to meet maximum residue limits (MRLs).

    Downstream process integration

    • Incorporation at wet mixing or emulsion formation stage for uniform dispersion;
    • Thermal stability checks after pasteurization or sterilization;
    • Finished goods analyzed for preservative distribution before final packaging;
    • QC release based on validated antioxidant assay methods.

    Final product types

    • Premium edible oils
    • Ready-to-eat convenience meals
    • High-moisture bakery and snack products
    • Dried fruit mixes for export markets
    Free Quote

    Competitive Cis-Miyabenol C prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

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    Certification & Compliance
    More Introduction

    Understanding Cis-Miyabenol C: What Sets Our Product Apart

    The Story Behind Our Cis-Miyabenol C

    Cis-Miyabenol C didn’t land in our catalog by accident. Our research team, working side-by-side with skilled production chemists, put in years isolating and characterizing natural resveratrol oligomers, with Cis-Miyabenol C standing out for its structure and reactivity. This compound caught the eye of organic chemists for a good reason—it displays characteristics quite unlike other polyphenols that regularly show up in our industry.

    Looking back to the first small-scale synthesis, the process started with sustainable plant sources, using extraction techniques we’ve refined over several decades. Our crew took on early purification challenges piece by piece, combining column chromatography with iterative crystallization steps. These efforts led to a reliable path for obtaining highly pure Cis-Miyabenol C at a scale that meets the needs of our clients in both research and industrial settings.

    Model and Specifications: More than Just Raw Numbers

    We produce Cis-Miyabenol C under the designation CMC-183, based on the first confirmed crystalline batch that met our internal benchmark for purity. Our routine QC runs confirm a purity above 98% by HPLC. You won’t see sticky residues or off-colors in our vials; each batch appears as a faint yellow to off-white powder, signaling the minimal oxidation and successful exclusion of tannic byproducts. The melting point falls within a very narrow range, and our analytical team keeps strict documentation for each lot produced.

    Attention to stability isn’t a throwaway feature. Cis-Miyabenol C tends to stick around as long as it’s kept away from direct sunlight and high humidity. We always remind lab staff—keep it sealed, store it at low temperature, and avoid repeated cycles of opening the container. The high-grade containers we use minimize moisture ingress, preventing clumping or hydrolysis that plagues lower-quality batches.

    Our Commitment to Transparency and Traceability

    We maintain complete records from raw material intake through to finished product packaging. These logs matter—not just for audits, but for anyone who wants to confirm batch integrity or track down the source of an anomaly. Our clients tell us they’ve spent too much time in the past chasing answers from suppliers who couldn’t verify the origin or purity of their compounds. We solve this by controlling every step inside our own facility.

    Shipments include a certificate of analysis based on results from our in-house infrared spectroscopy, NMR, and HPLC systems. These aren’t just checkboxes; our technical team reviews each chromatogram to guarantee that impurities stay well below industry-accepted thresholds.

    Real Uses, Everyday Impact

    Cis-Miyabenol C serves more than one niche. In multi-step organic synthesis, researchers choose it as a key intermediate due to its unique double bond configuration and reactive hydroxyl groups. It’s not just the molecule’s geometry at stake—this configuration directly affects downstream reactivity in coupling reactions, oxidation, and even hydrogenation steps.

    Pharmacology groups turn to it to probe structure-activity relationships across polyphenol classes. Its defined stereochemistry allows for comparisons against the trans isomer, revealing shifts in bioassay activity that raw extracts or mixed oligomers can’t provide. Some clients study its radical-scavenging activity, while others use it as a reference in antioxidant screening platforms.

    Food chemistry researchers see value in mapping its interaction with proteins and lipids. The subtle differences in configuration lead to different non-covalent bonding behavior in modeled digestive tracts. These kinds of studies push the field beyond qualitative “extract studies,” sharpens our understanding of polyphenolic uptake, metabolism, and efficacy.

    Differences from Other Polyphenols and Related Products

    One of the points we often drive home is that not all stilbenes or resveratrol oligomers behave the same way. Compare Cis-Miyabenol C against trans-Resveratrol, which gets most of the press in supplement markets. Cis-Miyabenol C has a trimeric structure that resists enzymatic hydrolysis better than the monomer. This isn’t just a matter of academic interest—clients working with in vivo systems report longer persistence and altered metabolic profiles, especially in microsomal stability assays.

    Stacking Cis-Miyabenol C beside Miyabenol A or trans-Miyabenol C highlights specific conformational and electronic differences. These changes matter to medicinal chemists designing inhibitors for ROS (reactive oxygen species) pathways or as candidates in neuroprotection screens. The cis form blocks certain metabolic transformations, changing how the compound interacts with cytochrome P450 enzymes. These subtle shifts can tip the balance in preclinical outcomes, making reliable access to the right isomer a must for anyone publishing serious work.

    From a synthetic standpoint, our compound also tolerates higher base concentrations during coupling reactions. This trait means mid-scale synthesis for analog generation becomes faster and requires fewer purification cycles—a tangible benefit when time and solvent cost count against your budget.

    Other suppliers may offer “resveratrol trimer” or unnamed “stilbenoid oligomers,” but comparison runs make differences clear. We’ve analyzed samples labeled as Miyabenol C by other manufacturers, only to find mixed isomer content or incomplete purification. Our investment in isomer-specific chromatography addresses this shortfall, so researchers using our material don’t second-guess the peaks in their own NMR spectra.

    Meeting Challenges, from Bench to Pilot Plant

    One enduring challenge in natural product manufacturing lies in the unpredictability of source material. Over the years, we’ve learned to hedge against crop failures and seasonal swings by banking critical intermediates ahead of time. Our lab team clocks extra shifts during high-yield harvest periods, extracting and storing precursor stocks in low-oxygen environments. This habit has paid off more than once when supply lines grew tight, demonstrating the value of planning several cycles ahead.

    We don't take shortcuts in the downstream processing. Small impurities in input biomass can mean big headaches later if not removed promptly. By investing in high-performance preparative LC and regular equipment upgrades, we’ve reduced stepwise yield loss and improved lot-to-lot reliability. Chemists who buy Cis-Miyabenol C from us know the powder in their bottle will match the powder in their publications, batch after batch.

    Feedback from process chemists prompted us to fine-tune drying cycles, so customers don’t face excessive static cling, slow reconstitution, or unexplained artifacts in their downstream reactions. This isn’t a luxury—it’s about letting other scientists focus on discovery instead of troubleshooting raw materials.

    Absorbing Feedback, Delivering on Promises

    Clients in fields as diverse as analytical standards, pharmaceutical leads, and food chemistry contact us regularly with requests for custom packaging, different lot sizes, or even alternate solvents for sample preparation. We answer these calls directly without passing customers through endless distributor chains. In one recent instance, a partner university needed small aliquots in amber microtubes to avoid photodegradation during transit; we debugged and delivered a working solution in days, not weeks.

    Over the years, a few common threads have emerged from this ongoing dialog. Researchers want to see consistency in their NMR, LC-MS, and optical rotation readings with every order. They ask for documentation of freeze-thaw stability so they can plan around grant deadlines or shifting research priorities. Our technical notes—drafted and updated after each real-world inquiry—help clear up confusion and put precise guidance into customers’ hands.

    Patents and licensing inquiries highlight another corner of our work. For groups looking to develop analogs or process patents based on trimeric stilbenes, our lot documentation and purity evidence become critical exhibits. Law firms and tech transfer offices often turn to us for authenticated reference material—these requests aren't theoretical. We respond quickly and keep detailed paperwork to iron out IP questions before they become roadblocks.

    The Real-World Importance of Authentic, High-Purity Material

    In some labs, one bad bottle of material sets a project back weeks—or makes published data irreproducible. Having been in the industry for decades, we’ve seen labs waste months isolating and characterizing their own batches of natural products only to find out the workload pulled key talent away from higher-value tasks. We stepped up to supply pre-vetted, fully characterized Cis-Miyabenol C so researchers can spend time solving bigger problems, not cleaning up bad inputs.

    Journals and review committees push for detailed material sourcing—“from where, which lot, how verified?” We supply direct answers and can provide authenticated analytical printouts so reviewers don’t flag ambiguity. This builds not just confidence, but also scientific reproducibility. Some of the biggest research groups in the field switched suppliers after spotting unexplained deviations in their reference spectra courtesy of impure or misidentified compounds. They shared their data, and we incorporated their learning into our protocols.

    In regulatory filings and commercial R&D, robust documentation sets real manufacturers apart from one-off bulk resellers. We show full traceability from field to flask, publishable NMR and HPLC, and storage histories with each shipment. Our clients keep this data on file for audits or patent claims—it’s become part of the everyday workflow.

    Looking Ahead: Innovation Through Collaboration

    The field of polyphenol chemistry continues to evolve as new biological targets and synthetic challenges emerge. We keep pace by investing in joint projects with universities, where our Cis-Miyabenol C serves as a stepping stone to even more complex analogs and probe molecules. Our chemists don’t just fill bottles; they trade notes on method tweaks, pilot novel purification protocols, and benchmark emerging analytics.

    Some of our most important improvements originated with open-minded scientists on the receiving end: one team developed a new antioxidant delivery system and provided feedback on solubility challenges that led us to offer an alternate form; another required rigorous deuterium labeling, prompting our group to hone isotopic enrichment techniques. Because we own our process and facility, we adapt quickly—putting practical science ahead of sales.

    Practical Guidance for Scientists and Process Engineers Using Cis-Miyabenol C

    Every year, we field hundreds of technical questions. For anyone working on their first synthesis, remember to dissolve Cis-Miyabenol C in dry solvents, as water content above trace levels impairs reactivity and can seed byproduct formation. Short exposures to heat during coupling steps don’t damage the molecule, but extended high temperatures can risk partial isomerization. We advise storing all unused material under argon at -20°C for optimum shelf life and labeling vials meticulously as we do in-house.

    Our clients in analytical chemistry often calibrate their methods with our reference material. We produce multi-gram lots on a routine basis, so repeat orders never feel rushed or piecemeal. Scale-up teams in pharmaceutical process development benefit from the consistent behavior of every batch when running reaction optimization or column method transfer. This saves time and eliminates costly backtracking.

    End-users sometimes report clumping or static build-up in finely powdered samples received from other suppliers. By screening for particle size at the last stage before bottling, we’ve cut this issue practically to zero. Clear communication keeps fresh challenges from going unaddressed. As demand grows for larger lots, we've expanded our pilot-scale reactors and recruited more hands-on chemists, resulting in even tighter batch-to-batch uniformity.

    Why Working with a Real Manufacturer Makes a Difference

    Direct sourcing from the facility that actually produces Cis-Miyabenol C cuts out layers of ambiguity and risk. We control the raw inputs, oversee every batch, and take full responsibility for technical support—no intermediaries, no doc chasing. In a climate where fake or relabeled material has entered the market from unknown sources, this line of sight is more than a selling point; it’s a practical form of risk management.

    Our plant makes room for small-batch specialty runs as well as routine production. Clients often ask for adaptation—be it a tweak to the drying step to customize flowability for automated dosing, or adjusting packaging to meet specialized shipping regulations. As the manufacturer, we stay nimble, talking chemist-to-chemist, delivering an experience that simply doesn’t exist through generic catalog resellers.

    Each member of our team takes pride in the traceability of their work. Hands-on involvement at every step means technical questions or troubleshooting are answered by someone who knows the process, not just a product code. This approach, built up through years of hands-on practice, shields our clients from pitfalls and lets their research and discovery run further, faster.

    Final Thoughts on Value, Reliability, and Advancing Science

    Anyone can order a compound online, but only a few can count on getting material that matches published research—down to the spectral lines and physical properties. We built our operation to meet that need, driven by the demands of real researchers who can’t afford to gamble months of work on an unreliable supplier. This reliability has become non-negotiable for leading labs and development teams worldwide.

    Science pushes forward when barriers drop between supply and discovery. By delivering consistently pure, isomer-defined Cis-Miyabenol C, supported with transparent data and technical engagement, we aim to close that gap. Every improvement—every time a customer calls in with feedback, every tweak to our documentation, every fine-tuned run in our production facility—matters. Our story with Cis-Miyabenol C continues to evolve through each scientist, engineer, and collaborator who uses our product to move their field ahead.