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Cis-Megastigma-5,8-Diene-4-One

    • Product Name Cis-Megastigma-5,8-Diene-4-One
    • Einecs 699-541-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    251955

    chemical_name Cis-Megastigma-5,8-Diene-4-One
    molecular_formula C13H18O
    molecular_weight 190.28 g/mol
    CAS_number 81786-73-4
    appearance Colorless to pale yellow liquid
    odor Woody, floral, fruity
    boiling_point About 265°C
    density Approximately 0.95 g/cm3
    solubility Insoluble in water, soluble in organic solvents
    refractive_index 1.509 - 1.515 (at 20°C)

    As an accredited Cis-Megastigma-5,8-Diene-4-One factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Cis-Megastigma-5,8-Diene-4-One is supplied in a 1g amber glass vial, tightly sealed with a tamper-evident cap.
    Shipping Cis-Megastigma-5,8-Diene-4-One should be shipped in tightly sealed containers, protected from light and moisture. Handle with care, avoiding excessive heat or direct sunlight. Comply with all local chemical transport regulations and include appropriate safety labeling and documentation. Store in a cool, dry place upon arrival.
    Storage Cis-Megastigma-5,8-Diene-4-One should be stored in a cool, dry, and well-ventilated area, away from direct sunlight and incompatible substances such as strong oxidizers. Keep the container tightly closed when not in use. Store at a controlled room temperature, ideally between 2–8°C, to maintain stability and prevent degradation. Ensure proper labeling and follow standard chemical storage protocols.
    Application of Cis-Megastigma-5,8-Diene-4-One

    Applications of Cis-Megastigma-5,8-Diene-4-One in Industrial Manufacturing

    As a direct producer of Cis-Megastigma-5,8-Diene-4-One, we support high-volume industrial clients across multiple targeted sectors. The compound’s unique molecular structure drives performance, compliance, and sensory outcomes in specialized manufacturing processes. Below, we detail its use in core markets and product workflows based on our direct supply experience.

    1. Fine Fragrance Compounding

    Cis-Megastigma-5,8-Diene-4-One acts as a key aroma material, imparting natural fruity and floral notes in high-end perfume and cologne formulations. Perfumers utilize its vibrant, long-lasting character for top and heart note creation, especially in premium blends targeting Western and Asian consumers. The raw material’s consistency, traceability, and organoleptic profile help fragrance houses meet regulatory and branding needs from ideation through bottling. Our strict QC ensures stable supply for global production runs.

    Industry compliance standards

    • IFRA Standards (current amendment)
    • EU Cosmetics Regulation (EC) No 1223/2009
    • REACH Registration (EC) No 1907/2006
    • RIFM safety evaluations

    Typical usage ratio

    • 0.01% – 0.15% of total fragrance concentrate
    • Adjustment based on desired intensity and target application (e.g., EDP vs. EDT)

    Downstream process integration

    • Added during initial compounding alongside other aroma chemicals and solvents
    • Filtration and stabilization post blending
    • Batch-wise QC sensory checks for each batch

    Final product types

    • Luxury perfumes
    • Eau de toilette
    • Body mists
    • Signature line colognes

    2. Flavour Additive in Beverage Concentrates

    The compound provides characteristic fruity and tropical taste notes in industrial-scale beverage flavour bases. Leading food manufacturers incorporate it into citrus and exotic blends for ready-to-drink juices, sodas, and non-alcoholic cocktails. Our material ensures batch-to-batch flavour reproducibility and is supported by full traceability documentation for regulatory audits and global exports. The high sensory threshold and thermal stability allow for use in pasteurized and UHT processed beverages without off-note formation.

    Industry compliance standards

    • FEMA GRAS (Flavor and Extract Manufacturers Association)
    • Codex Alimentarius Food Additive Standards
    • GB 2760 (China National Food Safety Standard for Food Additives)
    • 21 CFR §172.515 (FDA Food Flavoring Substances)

    Typical usage ratio

    • 1 – 12 ppm in finished beverage, depending on flavor profile requirements
    • Adjusted in pilot trials based on masking needs and matrix

    Downstream process integration

    • Direct dosing into beverage syrup or concentrate tanks
    • Homogenization followed by thermal processing (pasteurization/UHT)
    • Final QC via GC and sensory analysis before packaging

    Final product types

    • Juice drinks
    • Functional bottled beverages
    • Flavoured sparkling water
    • Cocktail mixer syrups

    3. Natural Ingredient in Premium Food Flavourings

    Cis-Megastigma-5,8-Diene-4-One offers nuanced tropical and peachy notes valued in natural food flavour formulations. Food additive suppliers and major F&B brands utilize the molecule to deliver authentic taste in bakery fillings, dairy desserts, and confectionery products. Attention to purity and non-GMO sourcing supports clean label trends and certification requirements vital for premium retail and export markets. Trace residual solvent and allergen absence records available for all industrial lots.

    Industry compliance standards

    • ISO 22000 Food Safety Management System
    • EU Food Flavour Regulation (EC) No 1334/2008
    • FCC (Food Chemicals Codex)
    • USDA Natural Flavor Guidelines

    Typical usage ratio

    • 2 – 30 ppm in final food product, depending on matrix (dairy, bakery, confection)
    • Precise calibration based on interaction with high-fat, low- or high-water matrices

    Downstream process integration

    • Incorporation in pre-mix or as a top-note additive in late-stage processing
    • Batch mixing followed by low- or high-heat treatment as required
    • Post-process QC for aroma retention and sensory panel validation

    Final product types

    • Yogurts and dairy desserts
    • Pastry and bakery fillings
    • High-end confectionery (candies, chews, jellies)
    • Shelf-stable fruit purées

    4. Aroma Standard for Analytical Laboratories

    Leading reference labs and quality control centers use Cis-Megastigma-5,8-Diene-4-One as a certified aroma standard. The compound enables accurate calibration in gas chromatography-olfactometry (GC-O) and flavor/fragrance panels. Traceable to ISO and ASTM specifications, each batch undergoes multi-step purification and COA validation for use in specialized analytical routines. Our direct manufacturing capability assures reliable supply for both external proficiency testing and internal QC method development.

    Industry compliance standards

    • ISO/IEC 17025 Laboratory Accreditation
    • ASTM E2886-13 (Sensory Analysis for Aroma Compounds)
    • Good Laboratory Practice (GLP)
    • Certificate of Analysis with full spectral and purity data

    Typical usage ratio

    • Standard preparation at 0.1 – 100 ppm for calibration solutions
    • Selected concentration based on target matrix and instrument sensitivity

    Downstream process integration

    • Weighing and dilution for analytical reference blends
    • Use as odor marker in SPME and GC-MS evaluations
    • Panel training for threshold and identification programs

    Final product types

    • GC reference standards
    • Sensory evaluation kits
    • Proficiency testing panels
    • Instrumental calibration mixes

    5. Specialty Ingredient in Tobacco Flavour Development

    Tobacco blending and flavour technology firms leverage this compound to engineer modern cigarette and novel oral product notes, delivering desirable stone fruit and creamy nuances in both heated tobacco and zero-combustion products. Tight controls on purity, thermal degradation byproducts, and allergen markers have made it viable for use in export blend innovation and regulatory registration. Process documentation supports compliance in tightly regulated geographies.

    Industry compliance standards

    • ISO 12863 (Cigarettes — Determination of ignition propensity)
    • Tobacco Products Directive 2014/40/EU (flavouring component rules)
    • US FDA Tobacco Product Ingredients Listing Guidance
    • Export market-specific disclosure requirements (e.g., PMTA for US)

    Typical usage ratio

    • 0.05 – 8 ppm in final tobacco blend or filler matrix
    • Concentration set based on blend type and local sensory regulations

    Downstream process integration

    • Mix-in with flavour pre-blend before spray-application onto tobacco sheet
    • Final QC checks for aroma persistence post-processing
    • Compliance documentation filed with regulatory authorities

    Final product types

    • Flavoured cigarettes
    • Heated tobacco sticks
    • Oral nicotine pouches
    • Tobacco flavour capsules

    6. High-Purity Reference Material for R&D and Academic Studies

    Public and private research organizations utilize this compound for sensory evaluation, metabolite tracing, and biosynthesis pathway analysis. Direct supply of high-purity lots with detailed spectral data meets strict study reproducibility and peer review standards. Documentation includes isotopic purity (if applicable), residual solvent, and impurity profiles facilitating advanced academic publishing and patent application data integrity.

    Industry compliance standards

    • ISO 9001:2015 Quality Management
    • IUPAC recommendations for reference materials
    • Good Research Practice (GRP) principles
    • Institutional Review Board (IRB) or ethics panel standards for study compounds

    Typical usage ratio

    • 1 – 1000 ppm based on test protocol and experimental design
    • Bench-level adjustment tested via GC-MS, LC-MS, or sensory threshold analysis

    Downstream process integration

    • Direct dissolution for test feeds or panel sensory dosing
    • Use as isotope-labeled tracer in metabolic studies (where available)
    • Authentication and reference spike in analytical runs

    Final product types

    • Peer-reviewed research results
    • Biosynthetic pathway mapping datasets
    • Sensory analysis reports
    • Intellectual property submissions
    Free Quote

    Competitive Cis-Megastigma-5,8-Diene-4-One prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

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    Certification & Compliance
    More Introduction

    Cis-Megastigma-5,8-Diene-4-One: A Distinct Aroma Ingredient Straight from Our Production Line

    Our Experience With Cis-Megastigma-5,8-Diene-4-One

    Years on the plant floor have shown that the smallest molecules can lead to the biggest leaps in flavor and fragrance design. Cis-Megastigma-5,8-Diene-4-One fits this perfectly. As a manufacturer, we see every step, every bit of raw input, every subtle challenge in purification, and most importantly, the power of a well-made molecule in action. It's not just about turning out kilos; getting this chemical right means hitting the precise notes our customers need—no strange off-notes, no instability, no batch variation creeping in. Reliable output isn't a marketing promise for us—it's a daily responsibility.

    Molecular Model and Production Know-How

    This compound, cis-Megastigma-5,8-diene-4-one, stands out due to its structure and sensory profile. The backbone features the classic C13 megastigmane structure, made famous by its close relatives in natural aroma chemistry. Achieving a consistent cis/isomer ratio remains a challenge in bulk production, but we've invested in processes that let us correct course at every step. In the lab, analytical GC and NMR assays guide our technicians; on the floor, purification and distillation runs get fine-tuned using actual olfactory checks—not just numbers on a report. Small differences in isomer content can produce massive changes in the final aroma impression. Our years in the field taught us to never cut corners with cyclization. The right balance gives you a delicate yet persistent fruity, tea-like, slightly woody strength that works both in classic flavor tonality and new modern bases. Ash content gets carefully tracked before every isolation step to avoid trace residues that could dull its brightness in application.

    Specifications and Batch Consistency Matter

    For us, specifications are not just lines on a certificate—they’re hard-won know-how. Purity by GC spans the upper nineties, side impurities drop below the sensory threshold, and no stabilizer interferes. Production runs yield material in a light, almost water-clear state, with a volatility profile familiar to perfumers who know traditional megastigmane derivatives. Olfactometry confirms every batch; our teams sample for consistency because we’ve seen how nature-inspired volatiles lose their character when contaminated, even at parts-per-million levels. Stability remains a constant focus. The packaging standard grew out of our early experience: supply in inert-gas-flushed drums stops the product from picking up unwanted oxygen or off notes. No unnecessary add-ons, just pure material with an unmistakable aroma identity intact from factory to formulator. This detail pays off for customers blending in concentrate or re-bottling for their own finished mixtures; everything holds its profile batch after batch.

    Main Uses: Inside Flavors, Fragrances, and More

    Cis-Megastigma-5,8-diene-4-one gets noticed in the industry for its genuine aroma strength and versatility. Everyone in our sector knows it as a core character in fruit and tea profiles, with natural close relatives found in blackcurrant buds, osmanthus, and several exotic fruits. From my past life in the flavor lab, I remember how formulators found weak spots in compositions lacking this specialized ketone. One or two drops transform a dull green-tea accord into something with real, freshly brewed nuances; a stone-fruit note jumps to life with a bit of this material sitting at the heart. Flavorists often reach for cis-Megastigma-5,8-diene-4-one to fill in that grated, zesty top-note that doesn’t come simply from linalool or straight decenal. It fits comfortably in peach, apricot, mango, and tea flavors, not by brute strength but by complexity—an edge you can’t fake using standard esters. I’ve worked with creative perfumers who insist on this molecule for high-end floral accords (think osmanthus and freesia), where its green-fresh transparency comes through, yet doesn’t overpower. In beverage and confection formats, our food-grade production process becomes vital. It must consistently meet strict purity needs—tiny traces of byproducts can throw a whole flavor system out of balance. Over the years, customer feedback led us to further fine-tune our filtration and distillation, helping flavor houses add our product to clear beverages or delicate syrup blends without a hitch. That’s been a real evolution, shaped by actual application, not just internal targets.

    Distinctive Differences Compared to Other Megastigmane Compounds

    Formulators often ask how cis-Megastigma-5,8-diene-4-one diverges from well-known counterparts like beta-ionone or damascone derivatives. The answer comes back to nuance. Where beta-ionone delivers a classic violet-floral profile, and beta-damascone explodes with more obvious berry and rose notes, the cis-5,8-diene-4-one skirts the edge—leaning lighter, fresher, with a certain tea-leaf dryness and trace fruit tartness. It’s much less weighty, almost never “muddy” if used with restraint, and gives a much-needed boost when the floral heart gets cloying or too sweet. Unlike ionones, it will not overload a formulation or bury delicate green notes in floral or fruity blends. Its persistence stays for hours without clinging too tightly to the base, so it shines in middle-to-top-note layering. Perfumers crafting luxury or artisanal scents turn to it for this—the transparent lift, the clarity, the authentic fruitiness without a hint of artificiality, something years in hands-on blending have made clear.

    Working Direct From The Production Source

    Customers working with cis-Megastigma-5,8-diene-4-one depend on product integrity at every stage. Coming straight from a manufacturing setup like ours, transparency and technical support aren’t add-ons; they underpin every order. Our technical teams, not just sales staff, regularly talk with clients about real-life behavior in compound formulation. Over the years, we’ve helped trouble-shoot solubility glitches, trace off-note problems, and optimize dosing guidelines. Sometimes a simple adjustment in pH or blending protocol can unlock the real potential of this molecule, but only if you get it from people who understand both chemistry and aroma design. International regulations now push producers to go way beyond basic compliance—clean sourcing, full process traceability, and built-in batch security. On the floor, this means documenting every run, archiving samples, and keeping analytical screens open to new emerging contaminants other suppliers sometimes overlook. Our clients get near-real-time quality reports and know that every container started at one verified production point, not a patchwork of intermediaries.

    Sustainability: Sourcing and Scale

    Over two decades in industrial aroma production, we’ve seen the demand for clean-label, traceable, and sustainable aroma chemicals rise faster than ever. Sourcing megastigmane raw materials for cis-5,8-diene-4-one used to mean chasing scarce plant-derived feedstock. Our current process leans on established synthetic routes, cutting dependency on natural harvest cycles, and letting us overlay strict quality control at every step. This matters for ethical sourcing and for giving customers long-term consistency—no wild seasonal spikes in aroma, no unpredictable flavor shifts. There’s a lot of talk about biocatalytic routes and green chemistry. We’ve invested in R&D here, not just for regulatory compliance, but to cut our own waste and energy use. A new catalytic step slashed solvent waste by half, and by recycling process heat at scale we dropped electricity use across the batch plant—a quantifiable impact on footprint, not just marketing spin. These realities drive our pricing position, our reliability, and our ability to commit to long-term flavor partnerships, even as global rules keep shifting.

    Application Insights: Bringing Out The Best

    Cis-Megastigma-5,8-diene-4-one isn’t a plug-and-play ingredient—it works best in the hands of skilled formulators who understand the trick of balancing complex fruit and floral profiles. Through direct feedback and our own trial blends, we found that dosing levels as low as two or three parts per million in the final blend can create a dramatic natural lift, especially in tea, peach, and lychee cases. It's about connecting the molecule’s inherent brightness with the pulse of the rest of the composition, not just layering on power. Our customers continually surprise us with new applications—from boosting authenticity in “clean label” fruit preparations, to making non-alcoholic drinks taste more like freshly picked produce. There’s a world of difference between a basic flavor that mimics fruit and one that genuinely evokes the complexity of nature. That’s the gap this molecule bridges. In many beverage systems, its volatility needs careful handling during processing and filling—heat and oxygen management from mixing to final packaging can help run its performance up a notch. That’s where close collaboration between the manufacturer and the flavor house pays off, both technically and in final consumer experience.

    Challenges, Realities, and Solutions on The Production Floor

    No aroma chemical reachers the market without challenges worth mentioning. Early on, we encountered technical hurdles in achieving complete separation of isomeric impurities. Tuning reaction conditions—temperature, catalyst profile, and exact reactant ratios—needed long periods of iteration. We’ve seen how a seemingly minor change in upstream substrate can knock the final aroma profile off track, so every major parameter got stress-tested. Taste panels at every point guide adjustment steps, not just numbers from machines. Transportation can challenge this molecule’s stability too; it doesn’t ask for coddling, but keeping headspace oxygen in the drum low and the product cool stops any trace oxidative drift. Sometimes simple process tweaks, such as swapping seals or changing the order material is drawn, made the difference between lasting freshness and a slight, unwanted top-note. All of these fixes came from experience and honest troubleshooting sessions between plant technicians and clients, never from remote corporate policy.

    Supporting Real Transparency, Not Just Buzzwords

    Anyone in the field can print a specification sheet or talk about purity. Consistent performance, real documentation, traceability through each batch, open access to technical teams—these are the benchmarks that separate direct manufacturers from impersonal trading companies. Over the years, we’ve taken the long view: open our doors to client visits, share technical data as it comes off the line, and empower R&D partners with more than just samples—real insights into process, supply stability, and potential touchpoints for co-development. It’s not just a matter of keeping up with certifications or compliance: it’s about building a long-term, experience-backed relationship where every molecule meets its promise from batch one to batch hundred. For a molecule as distinctive as cis-Megastigma-5,8-diene-4-one, standing behind the origin story matters, because a flavor house or perfumer only needs one small miss in supply or aroma profile to lose the trust of their end customer.

    Why This Product Matters Now More Than Ever

    The search for authentic, stable, and high-impact aroma ingredients pushes manufacturers like us to the frontlines of quality, transparency, and technical problem-solving. With global supply networks stretched and consumer expectations rising, the standards for flavor and fragrance ingredients climb ever higher. Producers have to dig deep—regular audits, strategic investments in greener tech, robust technical training right on the shop floor—to stay ahead. Across our customer base, demand shifts fast. Applications move from traditional flavor houses and fragrance compounding into new clean-label drinks, unique confectionery lines, niche perfumeries, and even innovative culinary blends. The bar for authenticity keeps rising, and every time a customer down the chain tastes or smells a finished product, that’s the ultimate test of our work. As origin manufacturers, we shoulder this responsibility in every kilo we deliver—knowing that each one carries a signature built from honest, hands-on production, not cut corners or shortcuts.

    Looking Ahead: Partnering for Quality and Innovation

    Cis-Megastigma-5,8-diene-4-one occupies a unique spot among aroma chemicals—not for mass-market flavor, but for applications where detail, accuracy, and technical support mean the difference between average and remarkable. For brands pushing the edge of fruit and floral authenticity, and perfumers seeking rare, transparent nuances impossible from more common megastigmane derivatives, direct access to a solid manufacturing partner becomes mission-critical. With every new regulatory challenge, every shift in consumer taste, and every customer innovation, we’re committed to bringing not only a reliable product, but genuine insight, transparency, and support. Our experience means we don’t just understand this molecule—we’ve shaped it, optimized it, and delivered it to the world’s best flavorists and perfumers. For us, that’s both the challenge and the long-term reward of making aroma chemistry direct, accessible, and truly dependable.